LOCUS       NZ_CP035434            41176 bp    DNA     circular CON 24-JUL-2024
DEFINITION  Streptococcus pyogenes strain emm75.1 chromosome, complete genome.
ACCESSION   NZ_CP035434
VERSION     NZ_CP035434.1
KEYWORDS    RefSeq.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1887700)
  AUTHORS   Davies,M.R., McIntyre,L., Mutreja,A., Lacey,J.A., Lees,J.A.,
            Towers,R.J., Duchene,S., Smeesters,P.R., Frost,H.R., Price,D.J.,
            Holden,M.T.G., David,S., Giffard,P.M., Worthing,K.A., Seale,A.C.,
            Berkley,J.A., Harris,S.R., Rivera-Hernandez,T., Berking,O.,
            Cork,A.J., Torres,R.S.L.A., Lithgow,T., Strugnell,R.A., Bergmann,R.,
            Nitsche-Schmitz,P., Chhatwal,G.S., Bentley,S.D., Fraser,J.D.,
            Moreland,N.J., Carapetis,J.R., Steer,A.C., Parkhill,J., Saul,A.,
            Williamson,D.A., Currie,B.J., Tong,S.Y., Dougan,G. and Walker,M.J.
  TITLE     Atlas of group A streptococcal vaccine candidates compiled using
            large scale comparative genomics
  JOURNAL   Nat. Genet. (2019) In press
REFERENCE   2  (bases 1 to 1887700)
  AUTHORS   Davies,M.R., McIntyre,L., Mutreja,A., Lacey,J.A., Lees,J.A.,
            Towers,R.J., Duchene,S., Smeesters,P.R., Frost,H.R., Price,D.J.,
            Holden,M.T.G., David,S., Giffard,P.M., Worthing,K.A., Seale,A.C.,
            Berkley,J.A., Harris,S.R., Rivera-Hernandez,T., Berking,O.,
            Cork,A.J., Torres,R.S.L.A., Lithgow,T., Strugnell,R.A., Bergmann,R.,
            Nitsche-Schmitz,P., Chhatwal,G.S., Bentley,S.D., Fraser,J.D.,
            Moreland,N.J., Carapetis,J.R., Steer,A.C., Parkhill,J., Saul,A.,
            Williamson,D.A., Currie,B.J., Tong,S.Y., Dougan,G. and Walker,M.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2019) Department of Microbiology and Immunology,
            University of Melbourne, The Doherty Institute of Infection and
            Immunology, Melbourne, Victoria 3000, Australia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 80x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_005163865.1-RS_2024_07_24
            Annotation Date                   :: 07/24/2024 01:48:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,868
            CDSs (total)                      :: 1,779
            Genes (coding)                    :: 1,714
            CDSs (with protein)               :: 1,714
            Genes (RNA)                       :: 89
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 36 of 65
            Pseudo Genes (incomplete)         :: 31 of 65
            Pseudo Genes (internal stop)      :: 25 of 65
            Pseudo Genes (multiple problems)  :: 24 of 65
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:28:47
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1152201
            Orig. end                         :: 1193377
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP035434.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..41176
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="T3PKS"
                     /region_number="3"
                     /rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /tool="antismash"
     cand_cluster    1..41176
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /kind="single"
                     /product="T3PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..41176
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:21176](+)"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..21176
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
     gene            complement(782..1432)
                     /locus_tag="ETT65_RS05965"
                     /old_locus_tag="ETT65_05965"
     CDS             complement(782..1432)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057640.1"
                     /locus_tag="ETT65_RS05965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_05965"
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_003061805.1"
                     /transl_table=11
                     /translation="MINIPLMKDSLGFVLSGLPYTLGISLLSFFTGLFLGLGLALLGRS
                     RQPLIHYLVRAYISIMRGVPMIVVLFVLYFGLPYYGLELPALLCAYLGFSMVSAAYISE
                     VFRSSIEAIDKGQWEAAKALGLPYALMVKKIILPQAFRIAVPPLGNVIIDMVKSSSLAA
                     MITVPDIFQNAKIIGGREWDYMSMYILVAFIYWLIAFLLERYQEFLENKLALV"
     gene            complement(1461..2324)
                     /locus_tag="ETT65_RS05970"
                     /old_locus_tag="ETT65_05970"
     CDS             complement(1461..2324)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061079.1"
                     /locus_tag="ETT65_RS05970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_05970"
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="WP_029713992.1"
                     /transl_table=11
                     /translation="MKKSVTLLSIGLASLLLAACAPHQSQKSSWDTIKEKGVLKVATPG
                     TYQPTSFYNDNNELVGYEVDMVKEIGKRLNIKVKFVETGFDQAFTSVDSGRVDISLNNF
                     DITPKRQKKYNISTPYKYGVGGMIVRADGSSNMAKKDLSDWKGKKAAGASGTEYMKVAQ
                     KQGAELVTYDNVTGDVYLNDVANGRTDFIPNDYPAQKLFVDYMLSQNPNLNVKMSDVQY
                     NPTEQGIVMNKKDDSLKKKIDAVIKDMIKDGSLKKISETYYAGQDLTKPFGKDKKIPVI
                     DTKDVN"
     gene            complement(2442..3896)
                     /locus_tag="ETT65_RS05975"
                     /old_locus_tag="ETT65_05975"
     CDS             complement(2442..3896)
                     /EC_number="3.5.1.4"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1105: amidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407508.1"
                     /locus_tag="ETT65_RS05975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_05975"
                     /product="amidase"
                     /protein_id="WP_002994017.1"
                     /transl_table=11
                     /translation="MTYQDATAMAIAVQTGQTTPLELVTQAIYKAKKLNPTLNAITSER
                     FEAALEEAKQRDFSGLPFAGVPLFLKDLGQELKGHSSTSGSRLFKEYQATKTDLFVKRL
                     EALGFIILGRSNTPEFGFKNISDSSLHGPVNLPKDNTRNAGGSSGGAAALVSSGISALA
                     TASDGGGSIRIPASFNGLIGLKPSRGRMPVGPGSYRSWQGASVHFALTKSVRDTRNLLY
                     YLQMEQMESPFPLATLTKDSIYQSLQRPLTIAFYQRLSDGSPVSLDTAKALRQAVTWLR
                     EQGHQLVELEEFPVNMTEVIRHYYIMNSVETAAMFADIEDTFGRPMTKDDMETMTWAIY
                     QSGKDIPAWRYSQVLQKWDTYSATMASFHETYDLLLTFTTNTPAPKHGELVPDSKLMAN
                     LAQAEIFSSEEQFNLVETMFGKSLAINPYTALPNLTGQPAISLPTYETKEGLPMGIQLI
                     AAKGREDLLLGIAEQFEAAGLLKIPQ"
     gene            complement(4093..4722)
                     /gene="pyrE"
                     /locus_tag="ETT65_RS05980"
                     /old_locus_tag="ETT65_05980"
     CDS             complement(4093..4722)
                     /EC_number="2.4.2.10"
                     /GO_function="GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pyrE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922180.1"
                     /locus_tag="ETT65_RS05980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_05980"
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="WP_002990137.1"
                     /transl_table=11
                     /translation="MTLASQIATQLLDIKAVYLKPEDPFTWASGIKSPIYTDNRVTLSY
                     PKTRDLIENGFVETIRAHFPEVEVIAGTATAGIPHGAIIADKMTLPFVYIRSKPKDHGA
                     GNQIEGRVLKGQKMVIIEDLISTGGSVLDAAAAASREGADVLGVVAIFTYELPKASQNF
                     KEAGIKLITLSNYTELIAVAKLQGYITNDGLHLLKKFKEDQVNWQQ"
     gene            complement(4780..5472)
                     /gene="pyrF"
                     /locus_tag="ETT65_RS05985"
                     /old_locus_tag="ETT65_05985"
     CDS             complement(4780..5472)
                     /EC_number="4.1.1.23"
                     /GO_function="GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA]"
                     /GO_process="GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="pyrF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984921.1"
                     /locus_tag="ETT65_RS05985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_05985"
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="WP_011184421.1"
                     /transl_table=11
                     /translation="MKEERPIIALDFSSFEETKAFLDLFPAEEKLYVKIGMELYYAQGP
                     DIVRYIKSLGHNVFLDLKLHDIPNTVRAAMAVLKELDIDMATVHAAGGVEMLKAAREGL
                     GQGPTLIAVTQLTSTSEDQMRGDQNIQTSLLESVLHYSKGAAKAQLDGVVCSAQEVEAI
                     KAVTPTGFTCLTPGIRPKGSNIGDQKRVMTPNQARRIGSDYIVVGRPITQAKDPVAAYQ
                     AIKAEWAG"
     gene            complement(5749..6285)
                     /locus_tag="ETT65_RS05990"
                     /old_locus_tag="ETT65_05990"
     CDS             complement(5749..6285)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990141.1"
                     /locus_tag="ETT65_RS05990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_05990"
                     /product="hypothetical protein"
                     /protein_id="WP_020905099.1"
                     /transl_table=11
                     /translation="MNVTEQNSHQILIQKLLVSIHYLTLFRDELKLVERTPSILGGEFP
                     AHLVQSELGDIVAAIDTLDMQQRLIESTFWYEESAFKLMNKTLDIVDNWIKGVDHLIDL
                     CQSKEVFQIIIGDKRIRVFGVLSDVFSSLKVSALSLKEAPIPDVLYEHIQRVNLEEEAF
                     IKYYQSPKIPTGEFE"
     gene            6507..7412
                     /locus_tag="ETT65_RS05995"
                     /old_locus_tag="ETT65_05995"
     CDS             6507..7412
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284709.1"
                     /locus_tag="ETT65_RS05995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_05995"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_023079084.1"
                     /transl_table=11
                     /translation="MRIQQLHYIIKIVECGSMNEAAKQLFITQPSLSNAVKDLEMEMGI
                     TIFNRNPKGITLTKDGVEFLSYARQIIEQTSLLEDRYKNHNTGRELFSVSSQHYAFVVN
                     AFVSLLKRTDMTRYELFLRETRTWEIIDDVKNFRSEIGVLFINDYNRDVLTKLFDDNHL
                     TASPLFKAQPHIFVSKSNPLATKSLLSMDDLSDFPYLSYDQGIHNSFYFSEEMMSQMPH
                     NKSIVVSDRATLFNLMIGLDGYTVASGILNSNLNGDQIVAIPLDVPDEIDIVFIKHEKA
                     NLSKMGERFIEYLLEEVTFD"
     gene            complement(7492..8280)
                     /locus_tag="ETT65_RS06000"
                     /old_locus_tag="ETT65_06000"
     CDS             complement(7492..8280)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984926.1"
                     /locus_tag="ETT65_RS06000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_06000"
                     /product="LytR family transcriptional regulator"
                     /protein_id="WP_136097850.1"
                     /transl_table=11
                     /translation="MTNNQTLDILLDVYAYNHAFRIAKALPNIPKTALYLLEMLKERRE
                     LNLAFLAEHAAENRTIEDQYHCSLWINQSLEDEQIANYILDLEVKVKNGAIIDFVRSVS
                     PILYRLFLRLITSEIPNFKAYIFDTKNDQYDTWHFQAMLESDHEVFKAYLSQKQSRNVT
                     TKSLADMLTLTSLPQEIKDLVFLLRHFEKAVRNPLAHLIKPFDEEELHRTTHFSSQAFL
                     ENIITLATFSGVIYRREPFYFDDMNAIIKKELSLWRQSIV"
     gene            complement(8273..8986)
                     /gene="deoD"
                     /locus_tag="ETT65_RS06005"
                     /old_locus_tag="ETT65_06005"
     CDS             complement(8273..8986)
                     /EC_number="2.4.2.1"
                     /GO_function="GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene="deoD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984928.1"
                     /locus_tag="ETT65_RS06005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_06005"
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="WP_136075104.1"
                     /transl_table=11
                     /translation="MSIHISAKKGDIADKILLPGDPLRAKFIAENFLEDAVCFNEVRNM
                     FGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKTLIRVGTAGAIDPEVHVRELV
                     LAQAAATNSNIIRNDFPEFDFPQIADFGLLDKAYHIAREMGVTTHVGNVLSSDVFYTNM
                     PERNMALGKLGVKAIEMEAAALYYLAAQHHVKALGIMTISDNLNNPTEDTTAEERQTTF
                     TDMMKVGLETLIAND"
     misc_feature    9358..9371
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.2"
                     /tool="antismash"
     gene            complement(9571..10380)
                     /locus_tag="ETT65_RS06010"
                     /old_locus_tag="ETT65_06010"
     CDS             complement(9571..10380)
                     /EC_number="2.4.2.1"
                     /GO_function="GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647060.1"
                     /locus_tag="ETT65_RS06010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_06010"
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="WP_003053715.1"
                     /transl_table=11
                     /translation="MSLMTKINETKDFLVAKGIEAPEFGLILGSGLGELAEEVENPVVI
                     DYADIPNWGKSTVVGHAGKLVYGDLAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKALG
                     CEGVLVTNAAGGIGYGPGTLMAITDHINMTGNNPLIGENLDEFGPRFPDMSDAYTKVYR
                     NKAHEVAEKMNIKLEDGVYMGLTGPTYETPAEIRAFKVLGADAVGMSTVPEVIVAAHSG
                     LKVLGISAITNFAAGFQSELNHEEVVEVTEHIKEDFKGLVKAILAEL"
     gene            complement(10364..10805)
                     /gene="arsC"
                     /locus_tag="ETT65_RS06015"
                     /old_locus_tag="ETT65_06015"
                     /pseudo=""
     CDS             complement(10364..10805)
                     /GO_function="GO:0008794 - arsenate reductase
                     (glutaredoxin) activity [Evidence IEA]"
                     /GO_process="GO:0046685 - response to arsenic-containing
                     substance [Evidence IEA]"
                     /codon_start=1
                     /gene="arsC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922177.1"
                     /locus_tag="ETT65_RS06015"
                     /note="This arsenate reductase requires both glutathione
                     and glutaredoxin to convert arsenate to arsenite, after
                     which the efflux transporter formed by ArsA and ArsB can
                     extrude the arsenite from the cell, providing resistance.;
                     frameshifted; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_06015"
                     /product="arsenate reductase (glutaredoxin)"
                     /pseudo=""
                     /transl_table=11
                     /translation="MEEITIYHNPNCGTSRNVLAMIRHAGIEPTIIEYLQTPPNRETLI
                     ELLQSMGISARELLRTNVPEFEAHGLANQAVAEKDIINAMLADPILINRPIVVTRKGVK
                     LCRPSETLLDILPVPLPSPYYERGWRECEPY"
     gene            complement(10821..12032)
                     /locus_tag="ETT65_RS06020"
                     /old_locus_tag="ETT65_06020"
     CDS             complement(10821..12032)
                     /EC_number="5.4.2.7"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008973 - phosphopentomutase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009117 - nucleotide metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184417.1"
                     /locus_tag="ETT65_RS06020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_06020"
                     /product="phosphopentomutase"
                     /protein_id="WP_136097849.1"
                     /transl_table=11
                     /translation="MSKFNRIHLVVLDSVGIGAAPDADKFFNAGVADTDSDTLGHISET
                     AGLSVPNMAKIGLGNISRPIPLKTVPTEDNPTGYVTKLEEVSLGKDTMTGHWEIMGLNI
                     TEPFDTFWNGFPEEILTKIEEFSGRKIIREANKPYSGTAVIDDFGPRQMETGELIVYTS
                     ADPVLQIAAHEDIIPVEELYKICEYARSITLERPALLGRIIARPYVGEPGNFTRTANRH
                     DYAVSPFQDTVLNKLADAGVPTYAVGKINDIFNGSGITNDMGHNKSNSHGIDTLIKTLQ
                     LPEFTKGFSFTNLVDFDANFGHRRDPEGYRDCLHEFDNRLPEIIANMKEDDLLLITADH
                     GNDPTYAGTDHTREYIPLLAYSVSFTGNGLIPQGHFADISATVAENFGVDTAMIGESFL
                     GHLK"
     gene            complement(12109..12792)
                     /gene="rpiA"
                     /locus_tag="ETT65_RS06025"
                     /old_locus_tag="ETT65_06025"
     CDS             complement(12109..12792)
                     /EC_number="5.3.1.6"
                     /GO_function="GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /gene="rpiA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881270.1"
                     /locus_tag="ETT65_RS06025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_06025"
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="WP_009881270.1"
                     /transl_table=11
                     /translation="MEALKKIAGVTAAQYVTDGMTIGLGTGSTAYYFVEEIGRRVKQEG
                     LQVVGVTTSSVTSKQAEGLGIPLKSIDDIDSIDLTVDGADEVDKDFNGIKGGGAALLME
                     KIVATPTKEYIWVVDASKMVEHLGAFKLPVEVVQYGADRLFRVFEKAGYKPSFRMKGDS
                     RLVTDMQNYIIDLDLGCIKDPVAFGHLLDGTVGVVEHGLFNGMVDKVIVASKDGVTVLE
                     APKAG"
     misc_feature    complement(13026..13039)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 22.77"
                     /tool="antismash"
     gene            13170..15269
                     /locus_tag="ETT65_RS06030"
                     /old_locus_tag="ETT65_06030"
     CDS             13170..15269
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1223: ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922175.1"
                     /locus_tag="ETT65_RS06030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_06030"
                     /product="AAA family ATPase"
                     /protein_id="WP_136097848.1"
                     /transl_table=11
                     /translation="MTHFSGKDPFVNMDDIFNQLMANMGGYRSENPRYLVNGREITPEE
                     FQHYRQTGQLPVATTKATNSQMLTPKADSVLTQLGTNLTQEARQGHLDPVIGRNKEIQD
                     TAEILARRTKNNPVLVGDAGVGKTAVIEGLAQAIVNGGVPAAIKNKEIVSIDISSLEAG
                     TQYRGSFEETIQNLIQEVKEAGNIILFFDEIHQIVGAGATSSDSGSKGLADILKPALSR
                     GELTLIGATTQDEYRNTILKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQHHHIT
                     LPDNVLKAAVDYSIQYIPQRSLPDKAIDLLDMTAAHLAAQHPVTDLKTLETEIAKQKER
                     QEKAVAKEDFEKALAAKTRIETLQKQIEQHNQSQNVTATVNDIAESVERLTGIPVSNMG
                     TNDLERLKGISSRLKSHVIGQDEAVAAVARAIRRNRAGFDDGNRPIGSFLFVGPTGVGK
                     TELAKQLALDLFGSKDAIIRLDMSEYNDRTAVSKLIGTTAGYVGYDDNNNTLTERVRRN
                     PYAIVLLDEIEKADPQIITLLLQVLDDGRLTDGQGNTINFKNTVIIATSNAGFGQQDTE
                     TSESNIMDRIAPYFRPEFLNRFNSIIKFNHLQKENLEEIVDLMLAEVNQTTAKKGISLT
                     IADDAKAHLIDLGYNHAMGARPLRRIIEQEIRDRITDYYLDHPEVKKLQAILKEGQLVI
                     RQNDQ"
     gene            complement(15327..16070)
                     /locus_tag="ETT65_RS06035"
                     /old_locus_tag="ETT65_06035"
     CDS             complement(15327..16070)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984942.1"
                     /locus_tag="ETT65_RS06035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_06035"
                     /product="hypothetical protein"
                     /protein_id="WP_002984942.1"
                     /transl_table=11
                     /translation="MTQVAQGRSKGKSLLCHQCNALFVFIIFLILLAVLFGVRYRNSSI
                     EGIWRTTSIDQKLGDDFAKRLTGLHQSPLIDDSLLTSSQMILTVKNNNVDLSFSVQVER
                     DIFVKRLAAYHQNELLKTLKENHLVVGDLSSKERQIIENSMPASHELEMILDQAFEKLA
                     SQIGGKYNQKTGHLSAVVLKGKVNRILHTIDIKEEVAAGHTSFSKGLLTPNGYFDYTRF
                     GKKLELLGDEKIIFKKALKKSPSSV"
     gene            complement(16218..16817)
                     /gene="yihA"
                     /locus_tag="ETT65_RS06040"
                     /old_locus_tag="ETT65_06040"
     CDS             complement(16218..16817)
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0043022 - ribosome binding [Evidence IEA]"
                     /GO_process="GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="yihA"
                     /gene_functions="other (smcogs) SMCOG1227: ribosome
                     biogenesis GTP-binding protein YsxC"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054379.1"
                     /locus_tag="ETT65_RS06040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_06040"
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="WP_002984945.1"
                     /transl_table=11
                     /translation="MAEEQVLNTHNASILLSAANKSHYPQDDLPEIALAGRSNVGKSSF
                     INTILGRKNLARTSSKPGKTQLLNFFNIDDKLRFVDVPGYGYAKVSKSERAKWGKMIEE
                     YLTSRDNLRAVVSLVDLRHAPSKEDIQMYDFLKYYDIPVIVVATKADKIPRGKWNKHES
                     VVKKALNFDKSDTFIVFSSVERIGIDDSWDAILEQV"
     gene            complement(16827..18056)
                     /gene="clpX"
                     /locus_tag="ETT65_RS06045"
                     /old_locus_tag="ETT65_06045"
     CDS             complement(16827..18056)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="clpX"
                     /gene_functions="other (smcogs) SMCOG1223: ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984948.1"
                     /locus_tag="ETT65_RS06045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_06045"
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="WP_002984948.1"
                     /transl_table=11
                     /translation="MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEI
                     IKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDRAKRALSVAVYNHYKRVSFTESRDD
                     DDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENILLK
                     LIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVP
                     PQGGRKHPNQEMIQIDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASY
                     MQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIQILTEPRNALVKQYQALLSYDG
                     VELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVE
                     GKSKPVLETA"
     gene            complement(18186..18356)
                     /locus_tag="ETT65_RS06050"
                     /old_locus_tag="ETT65_06050"
     CDS             complement(18186..18356)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302775.1"
                     /locus_tag="ETT65_RS06050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_06050"
                     /product="hypothetical protein"
                     /protein_id="WP_002984950.1"
                     /transl_table=11
                     /translation="MQRSIFGVFTAFLCVICVLCAIPAFKKNRYGLASLFLLNAFTNLV
                     NSIHAFYGTLF"
     gene            complement(18376..18873)
                     /locus_tag="ETT65_RS06055"
                     /old_locus_tag="ETT65_06055"
     CDS             complement(18376..18873)
                     /EC_number="1.5.1.3"
                     /GO_function="GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005542 - folic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984955.1"
                     /locus_tag="ETT65_RS06055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_06055"
                     /product="dihydrofolate reductase"
                     /protein_id="WP_002984955.1"
                     /transl_table=11
                     /translation="MTKEIIAIWAEDEAGLIGVAGKLPWYLPKELEHFKKTTLHQAILM
                     GRVTFEGMNCKRLPQRQTLVMTRNRDYQVDEVLTMTSIEKVLEWYHAQDKTLYIIGGNK
                     VLEAFNGYFDRIIKTVIHHRFKGDTYRPNLDFSHFTQESQTFYARDAKNPYDFTVTALK
                     HK"
     gene            complement(18953..19792)
                     /locus_tag="ETT65_RS06060"
                     /old_locus_tag="ETT65_06060"
     CDS             complement(18953..19792)
                     /EC_number="2.1.1.45"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /locus_tag="ETT65_RS06060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_06060"
                     /product="thymidylate synthase"
                     /protein_id="WP_011017679.1"
                     /transl_table=11
                     /translation="MTKADQIFKANIQKIINEGSLSEQARPKYKDGRTAHSKYITGAFA
                     EYDLAKGEFPITTLRPIPIKSAIKELFWIYQDQSNSLDVLEAKYNVHYWNEWEVDQTRT
                     IGQRYGAVVKKHDIISKILKQLAENPWNRRNVISLWDYEAFEETKGLLPCAFQIMFDVR
                     RVGEDLYLDASLTQRSNDILVAHHINAMQYVALQMMIAKHFGWKIGKFFYFVNNLHIYD
                     NQFDQAQELLKRQPVASQPKLVLNVPDGTNFFDIKPDDFELQNYDPVKPQLHFDLAI"
     misc_feature    complement(19748..19762)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 23.77"
                     /tool="antismash"
     gene            20001..21176
                     /locus_tag="ETT65_RS06065"
                     /old_locus_tag="ETT65_06065"
     CDS             20001..21176
                     /EC_number="2.3.3.10"
                     /GO_function="GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043: hydroxymethylglutaryl-CoA synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993959.1"
                     /locus_tag="ETT65_RS06065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_06065"
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="WP_014407506.1"
                     /sec_met_domain="Chal_sti_synt_N (E-value: 8.9e-07,
                     bitscore: 25.3, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIGIDKIGFATSQYVLKLEDLALARQVDPAKFSQGLLIESFSVA
                     PITEDIITLAASAADQILTDEDRAKIDMVILATESSTDQSKASAIYVHHLVGIQPFARS
                     FEVKQACYSATAALDYAKLHVASKPDSRVLVIASDIARYGVGSPGESTQGSGSIALLVT
                     ANPRILALNKDNVAQTRDIMDFWRPNYSFTPYVDGIYSTKQYLNCLETTWQAYQKRENL
                     QLSDFAAVCFHIPFPKLALKGLNNIMDNTVPPEHREKLIEAFQASITYSKQIGNIYTGS
                     LYLGLLSLLENSKVLQSGDKIGFFSYGSGAVSEFYSGQLVAGYDKMLMTNRQALLDQRT
                     RLSVSKYEDLFYEQVQLDDNGNANFDIYLTGKFALTAIKEHRRIYHTNDKN"
     gene            21163..22440
                     /locus_tag="ETT65_RS06070"
                     /old_locus_tag="ETT65_06070"
     CDS             21163..22440
                     /EC_number="1.1.1.88"
                     /GO_function="GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA]"
                     /GO_function="GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1187: hydroxymethylglutaryl-CoA reductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880299.1"
                     /locus_tag="ETT65_RS06070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_06070"
                     /product="hydroxymethylglutaryl-CoA reductase, degradative"
                     /protein_id="WP_111684958.1"
                     /transl_table=11
                     /translation="MTKTNLNWSGFSKKTFEERLQLIEKFKLLNAENLNQLKTDVLLPI
                     QTANQMTENVLGRLALPFSIAPDFLVNGSTYQMPFVTEEPSVVAAASFAAKLIKRSGGF
                     KAQTLNRQMIGQIVLYDIDQIDNAKAAILHKTKKLIALANKAYPSIVKRGGGARTIHLE
                     EKGEFLIFYLTVDTQEAMGANMVNTMMEALVPDLTRLSKGHCLMAILSNYATESLVTTS
                     CEIPVRLLDRDKTKSLQLAQKIELASRLAQVDPYRATTHNKGIFNGIDAVVIATGNDWR
                     AIEAGAHAYASRNGSYKGLSQWHFDQDKQVLLGQMTLPMPIASKGGSIGLNPTVSIAHD
                     LLNQPDAKTLAQLIASVGLAQNFAALKALTSSGIQAGHMKLHAKSLALLAGATQDEIAP
                     LVNALLADKPINLEKAHFYLSQLRQS"
     gene            complement(22670..23659)
                     /gene="fni"
                     /locus_tag="ETT65_RS06075"
                     /old_locus_tag="ETT65_06075"
     CDS             complement(22670..23659)
                     /EC_number="5.3.3.2"
                     /GO_function="GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="fni"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984966.1"
                     /locus_tag="ETT65_RS06075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_06075"
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="WP_010922169.1"
                     /transl_table=11
                     /translation="MTNRKDDHIKYALKYQSPYNAFDDIELIHHSLPSYDLSDIDLSTH
                     FAGQDFDFPFYINAMTGGSQKGKAVNEKLAKVAAATGIVMVTGSYSAALKNPNDDSYRL
                     HEVADNLKLATNIGLDKPVALGQQTVQEMQPLFLQVHVNVMQELLMPEGERVFHTWKKH
                     LAEYASQIPVPVILKEVGFGMDVNSIKLAHDLGIQTFDISGRGGTSFAYIENQRGGDRS
                     YLNDWGQTTVQCLLNAQGLMDQVEILASGGVRHPLDMIKCFVLGARAVGLSRTVLELVE
                     KYPTERVIAIVNGWKEELKIIMCALDCKTIKELKGVDYLLYGRLQQVN"
     gene            complement(23646..24659)
                     /locus_tag="ETT65_RS06080"
                     /old_locus_tag="ETT65_06080"
     CDS             complement(23646..24659)
                     /EC_number="2.7.4.2"
                     /GO_function="GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016126 - sterol biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635411.1"
                     /locus_tag="ETT65_RS06080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_06080"
                     /product="phosphomevalonate kinase"
                     /protein_id="WP_136097847.1"
                     /transl_table=11
                     /translation="MSNYCVQTGGKLYLTGEYAILTPGQKALIHFIPLMMTAEISPAAH
                     IQLASDMFAHKAGMTPDASYALIQATVKTFADYLGQSIDQLEPFSLIITGKMERDGKKF
                     GIGSSGSVTLLTLKALSAYYQITLTPELLFKLAAYTLLKQGDNGSMGDIACIAYQTLVA
                     YTSFDREQVSNWLQTMPLKKLLVKDWGYHIQVIQPALPCDFLVGWTKIPAISRQMIQQV
                     TASITPAFLRTSYQLTQSAMVALQEGHKEELKKSLAGASHLLKKLHPVIYHPKLVTLVA
                     ACQKQDAVAKSSGSGGGDCGIALAFNQNARDTLISKWQEADIALLYQERWGENDQP"
     gene            complement(24652..25596)
                     /gene="mvaD"
                     /locus_tag="ETT65_RS06085"
                     /old_locus_tag="ETT65_06085"
     CDS             complement(24652..25596)
                     /EC_number="4.1.1.33"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA]"
                     /GO_process="GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /gene="mvaD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888980.1"
                     /locus_tag="ETT65_RS06085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_06085"
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="WP_111684963.1"
                     /transl_table=11
                     /translation="MDPNVITVTSYANIAIIKYWGKENQAKMIPSTSSISLTLENMFTT
                     TSVSFLPDTATSDQFYINGVLQNDEEHTKISTIIDQFRQPGQAFVKMETQNNMPTAAGL
                     SSSSSGLSALVKACDQLFDTQLDQKALAQKAKFASGSSSRSFFGPVAAWDKDSGAIYKV
                     ETDLKMAMIMLVLNAAKKPISSREGMKLCRDTSTTFDEWVEQSAIDYQHMLTYLKTNNF
                     EKVGQLTEANALAMHATTKTANPPFSYLTKESYQAMEAVKELRQEGFACYFTMDAGPNV
                     KVLCLDKDLAQLAERLGKNYRIIVSKTKDLPDV"
     gene            complement(25578..26456)
                     /gene="mvk"
                     /locus_tag="ETT65_RS06090"
                     /old_locus_tag="ETT65_06090"
     CDS             complement(25578..26456)
                     /EC_number="2.7.1.36"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004496 - mevalonate kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016126 - sterol biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /gene="mvk"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054375.1"
                     /locus_tag="ETT65_RS06090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_06090"
                     /product="mevalonate kinase"
                     /protein_id="WP_002984974.1"
                     /transl_table=11
                     /translation="MNENIGYGKAHSKIILIGEHAVVYGYPAIALPLTDIEVVCHIFPA
                     DKPLVFDFYDTLSTAIYAALDYLQRLQEPIAYEIVSQVPQKRGMGSSAAVSIAAIRAVF
                     SYCQEPLSDDLLEILVNKAEIIAHTNPSGLDAKTCLSDHAIKFIRNIGFETIEIALNGY
                     LIIADTGIHGHTREAVNKVAQFEETNLPYLAKLGALTQALERAINQKNKVAIGQLMTQA
                     HSALKAIGVSISKADQLVEAALRAGALGAKMTGGGLGGCMIALADTKDMAEKISHRLKE
                     EGAVNTWIQML"
     gene            complement(26750..27982)
                     /locus_tag="ETT65_RS06095"
                     /old_locus_tag="ETT65_06095"
     CDS             complement(26750..27982)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888981.1"
                     /locus_tag="ETT65_RS06095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_06095"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_002990181.1"
                     /transl_table=11
                     /translation="MFNRIRIRFIMIASIAIFIILSSIVGIINTARCYQSQQEINRILH
                     LISSNKGKLPGTTESSKRLGTKLSEDSLSQFRYYSVIFNANGHLLSSNTANISALDREE
                     AQYFARLFAKSGEEKGSYRHQDSVYSYLITQLPNEEKLVVILDTTFYFRSVGDLLAVSM
                     MLAFGGFIFFVVLVSLFSGMVIKPFVQNYEKQRRFITNAGHELKTPLAIISANNELVEL
                     MTGESEWTKSTSDQVKRLTGLINQMITLARLEEQPDVVLHMVDFSAIAQDAAEDFKSLV
                     LKDGKRFDLTIQPNIMIKAEEKSLFELVTILVDNANKYCDPKGLVKVSLTTIGRRRKRA
                     KLEVSNTYLEGKSIDYSRFFERFYREDESHNSKEKGYGIGLSMAESMVKLFKGTITVNY
                     KNDAIVFTVVI"
     gene            complement(27991..28659)
                     /locus_tag="ETT65_RS06100"
                     /old_locus_tag="ETT65_06100"
     CDS             complement(27991..28659)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984985.1"
                     /locus_tag="ETT65_RS06100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_06100"
                     /product="response regulator transcription factor"
                     /protein_id="WP_002984985.1"
                     /transl_table=11
                     /translation="MKILLAEDEWQMSNVLTTAMTHQGYDVDVVFNGQEAIDKAKDNAY
                     DIMILDIMMPIKSGIEALKEIRASGNCSHIIMLTAMAEINDRVTGLDAGADDYLTKPFS
                     LKELLARLRSMERRVESFTPQVLQFAGVTLNINEQELSAGNAIRLASKEGKLMAFLMLN
                     QGKYLDTKTLYQHVWSDQEDYDTSIVWVYISYLRQKLLAIQANVIIAGDKDTSYCLLEK
                     "
     gene            complement(28662..29312)
                     /locus_tag="ETT65_RS06105"
                     /old_locus_tag="ETT65_06105"
     CDS             complement(28662..29312)
                     /GO_process="GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984988.1"
                     /locus_tag="ETT65_RS06105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_06105"
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="WP_053308300.1"
                     /transl_table=11
                     /translation="MKERLEHYSTSSIYSGFEVYLPLVLQTITDVIIAENIKSKKETGF
                     KLYEHFTSRIKSEASMIEKCQRKQLPLTSKSALKIIKDSIGIRIICGFIDDIYRMVDLL
                     KSIPGMSVNTEKDYILNAKPNGYRSYHLILELETHFPDILGEKKGCYFIEVQLRTIAQD
                     SWASLEHQMKYKHQVANAEMITRELKRCADELASCDVTMQTIRQLIQETTGEE"
     misc_feature    29448..29461
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.6"
                     /tool="antismash"
     misc_feature    29527..29540
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.3"
                     /tool="antismash"
     misc_feature    complement(29528..29541)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.93"
                     /tool="antismash"
     gene            29532..31544
                     /locus_tag="ETT65_RS06110"
                     /old_locus_tag="ETT65_06110"
     CDS             29532..31544
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1283: 2`,3`-cyclic-nucleotide 2`-phosphodiesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888982.1"
                     /locus_tag="ETT65_RS06110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_06110"
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="WP_136118652.1"
                     /transl_table=11
                     /translation="MKKYFILKSSVLSILTSFTLLVTDVQADQVDVQFLGVNDFHGALD
                     NTGTAYTPSGKIPNAGTAAQLGAYMDDAEIDFKQANQDGTSIRVQAGDMVGASPANSAL
                     LQDEPTVKVFNKMKFEYGTLGNHEFDEGLDEFNRIMTGQAPDPESTINDITKQYEHEAS
                     HQTIVIANVIDKKTNDIPYGWKPYAIKDIAINDKIVKIGFIGVVTTEIPNLVLKQNYEH
                     YQFLDVAETIAKYAKELQEQHVHAIVVLAHIPATSKDGVVDHEMATVMEKVNQIYPEHS
                     IDIIFAGHNHQYTNGTIGKTRIVQALSQGKAYADVRGTLDTDTNDFIKTPSANVVAVAP
                     GIKTENSDIKAIINHANDIVKTVTERKIGTATNSSTISKTENIDKESPVGNLVTTAQLT
                     IAKKTFPTVDFAMTNNGGIRSDLVVKNDRTITWGAAQAVQPFGNILQVIQMTGQHIYDV
                     LNQQYDENQTYFLQMSGLTYTYIDNDPKNSDTPFKIVKVYKDNGEEINLTTTYTVVVND
                     FLYGGGDGFSAFKKAKLIGAINTDTEAFITYITNLEASGKTVNATIKGVKNYVTSNLES
                     STKVNSAGKHSIISKVFRNRDGNIVSSEIISDLLTSTENTNNSLGKKETTTNKNTISSS
                     TLPITGDNYKMSPIMTILALISLGGLNAFIKKRKS"
     misc_feature    complement(29543..29556)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.33"
                     /tool="antismash"
     gene            complement(31625..32035)
                     /locus_tag="ETT65_RS06115"
                     /old_locus_tag="ETT65_06115"
     CDS             complement(31625..32035)
                     /EC_number="3.5.1.88"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017671.1"
                     /locus_tag="ETT65_RS06115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_06115"
                     /product="peptide deformylase"
                     /protein_id="WP_002984994.1"
                     /transl_table=11
                     /translation="MIREIITDHFLLQQKAQVAKKEDLWIGQDLQDTLAFYRQECLGMA
                     ANMIGEQKRIVIVSMGFIDLVMFNPVMVSKKGIYQTKESCLSLSGYRKTQRYDKITVEY
                     LDHNWRPKRLSLTGLTAQICQHELDHLEGILI"
     gene            complement(32291..32509)
                     /locus_tag="ETT65_RS09695"
                     /old_locus_tag="ETT65_06120"
     CDS             complement(32291..32509)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995561.1"
                     /locus_tag="ETT65_RS09695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_06120"
                     /product="hypothetical protein"
                     /protein_id="WP_002984997.1"
                     /transl_table=11
                     /translation="MALLFYYYVRKNQVKKLSQLKNLTEIFRKFIILTINNISVIKAFQ
                     TAGVLFGPVKAANARESSIWFENLTKQ"
     gene            32740..32892
                     /locus_tag="ETT65_RS09840"
     CDS             32740..32892
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024729.4"
                     /locus_tag="ETT65_RS09840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="IS3 family transposase"
                     /protein_id="WP_367853175.1"
                     /transl_table=11
                     /translation="MDYCNNKRIKIKRKGLSPLQHRTKSFTSNRVANFWGSVQEHFFSI
                     ITCLL"
     gene            complement(32915..34792)
                     /locus_tag="ETT65_RS06130"
                     /old_locus_tag="ETT65_06130"
     CDS             complement(32915..34792)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922163.1"
                     /locus_tag="ETT65_RS06130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_06130"
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="WP_011054371.1"
                     /transl_table=11
                     /translation="MSHFLVEKLTKTVGDKTVFQDISFIIHDFDRIGIIGVNGTGKTTL
                     LDVLSGRLGFDGDHSPFSKANDYKIAYLTQDPEFNDASSVLDTVLSSDVKAIQLIRQYE
                     LLMANYTEDKQETLESLMSEMDRLDAWSIESDVKTVLSKLGITDLEQKVGDLSGGMRRR
                     VQLAQVLLGAADLLLLDEPTNHLDIDTIAWLTTYLKTAKKTVLFITHDRYFLDHVATRI
                     FELDKAGLTEYQGNYQDYVRLKAEQDERDAANLHKKKQLYKQELAWMRTQPQARATKQQ
                     ARINRFTDLKKEVHQDSSADKLEMAFETSRIGKKVIHFEDLSFAYGDRQLIKDFNLIIQ
                     NKDRIGIVGDNGVGKSTLLNIINGDLKPTSGKLDIGDTIRVGYFSQQLKDMDETKRVIN
                     YLQEVADEVKTSVGTTSISELLEQFLFPRSSHGTLIAKLSGGEKKRLYLLKLLIEKPNV
                     LLLDEPTNDLDIATLTVLENFLANFAGPVITVSHDRYFLDKVATKILAFEEGDIRVFYG
                     NYSDYLDEKAFEKETVEADLAKAIVTEEVPLPPKEEKKRMSYLEKQEWAQIEDKIATIE
                     ANIEEIENQMLTVVSDYGQLAQLQKELDQRNNDLLLAYERFEYLSGLDI"
     gene            complement(34789..35997)
                     /locus_tag="ETT65_RS06135"
                     /old_locus_tag="ETT65_06135"
     CDS             complement(34789..35997)
                     /EC_number="2.7.7.72"
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880307.1"
                     /locus_tag="ETT65_RS06135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_06135"
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="WP_168436217.1"
                     /transl_table=11
                     /translation="MKLMTMPSEFQKALPILTKIKEAGYEAYFVGGSVRDVLLERPIHD
                     VDIATSSYPEETKAIFNRTVDVGIEHGTVLVLENGGEYEITTFRTEDVYVDYRRPSQVS
                     FVRSLEEDLKRRDFTVNALALDENGRVIDKFRGLIDLKQKRLRAVGKAEERFEEDALRI
                     MRGFRFAASLDFDIEAATFEAMRSHSSLLEKISVERSFTEFDKLLTAPHWRKGISAMIA
                     CQAYDYLPGLKQQEAGLNHLIVSLKDNFTFSDHHQAWAYVMISLAIEDPKSFLKAWKTS
                     NDFQRYVTKLIALYRIRQERSFEKLDIYQYGKEMASLVEGLRKAQSLSVDMDHIEALDQ
                     ALAIHNKYDIVLNGSHLIKDFGMKPGPQLGLMLEKVELAIVEGRLDNDFTTIEAFVREE
                     LAT"
     gene            complement(36122..36970)
                     /locus_tag="ETT65_RS06140"
                     /old_locus_tag="ETT65_06140"
     CDS             complement(36122..36970)
                     /GO_function="GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985007.1"
                     /locus_tag="ETT65_RS06140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_06140"
                     /product="DegV family protein"
                     /protein_id="WP_002990194.1"
                     /transl_table=11
                     /translation="MKLAVITDSTATLPTDLKQDKAIFSLDIPVIIDDETYFEGRNLSI
                     DDFYQKMADSQNLPKTSQPSLSELDNLLGLLSSKGYTHVIGLFLAGGISGFWQNIQFLA
                     EEHPEIEMAFPDSKITSAPLGSMVKNVLDWSRQGMTFQAILNKLQEQIDGTTAFIMVDD
                     LNHLVKGGRLSNGSALLGNLLSIKPILRFDEEGKIVVYEKVRTEKKAMKRLVEILNDLI
                     ADGQYNVSIIHSKAQDKADYLKRLLQDSGYQYDIEEVHFGAVIATHLGEGAIAFGVTPR
                     L"
     gene            complement(36970..37350)
                     /locus_tag="ETT65_RS06145"
                     /old_locus_tag="ETT65_06145"
     CDS             complement(36970..37350)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985011.1"
                     /locus_tag="ETT65_RS06145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_06145"
                     /product="DUF1149 family protein"
                     /protein_id="WP_002985011.1"
                     /transl_table=11
                     /translation="MQLVREKEFVNQYHYDARNLEWEKENGTPETNFEVTFQLIDKDEQ
                     QKETVIVSVLQFVIVKEEFVISGVISQMVRILDRLVDKPSEFTQEEVESLAAPLLDMVK
                     RLTYEVTEIALDRPGIHLEFKN"
     gene            complement(<37552..37754)
                     /locus_tag="ETT65_RS06150"
                     /old_locus_tag="ETT65_06150"
                     /pseudo=""
     CDS             complement(<37552..37754)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051153.1"
                     /locus_tag="ETT65_RS06150"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="ETT65_06150"
                     /product="nucleoside-diphosphate kinase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MIKPYGFKYGLVGEVLRRIERLGFTFERLELRQASSKYLAKHDEA
                     LVINLFILDLKLT"
     misc_feature    complement(38156..38169)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.36"
                     /tool="antismash"
     misc_feature    38158..38171
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.42"
                     /tool="antismash"
     gene            38255..39280
                     /locus_tag="ETT65_RS06155"
                     /old_locus_tag="ETT65_06155"
     CDS             38255..39280
                     /EC_number="3.4.22.-"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922160.1"
                     /locus_tag="ETT65_RS06155"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases.; This family includes IgM or IgG-cleaving
                     cysteine proteases.; This family includes IgM or
                     IgG-cleaving cysteine proteases; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="ETT65_06155"
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="WP_002990201.1"
                     /transl_table=11
                     /translation="MRKRCYSTSAAVLAAVTLFALSVDRGVIADSFSANQEIRYSEVTP
                     YHVTSVWTKGVTPPAKFTQGEDVFHAPYVANQGWYDITKTFNGKDDLLCGAATAGNMLH
                     WWFDQNKEKIEAYLKKHPDKQKIMFGDQELLDVRKVINTKGDQTNSELFNYFRDKAFPG
                     LSARRIGVMPDLVLDMFINGYYLNVYKTQTTDVNRTYQEKDRRGGIFDAVFTRGDQSKL
                     LTSRHDFKEKNLKEISDLIKKELTEGKALGLSHTYANVRINHVINLWGADFDSNGNLKA
                     IYVTDSDSNASIGMKKYFVGVNSAGKVAISAKEIKEDNIGAQVLGLFTLSTGQDSWNQT
                     N"
     gene            39399..39665
                     /locus_tag="ETT65_RS06160"
                     /old_locus_tag="ETT65_06160"
     CDS             39399..39665
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014875.4"
                     /locus_tag="ETT65_RS06160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_06160"
                     /product="exotoxin beta-grasp domain-containing protein"
                     /protein_id="WP_269458357.1"
                     /transl_table=11
                     /translation="MDKDIVTIQEFDFKIRKFLMESKEIHLTKSPYIRGSLEIHSKNRK
                     HEKINLYDAKPNSTRSDVFKKYKDNKTINMKDFSHFDIYLWTK"
     gene            <39863..40180
                     /locus_tag="ETT65_RS06165"
                     /old_locus_tag="ETT65_06165"
                     /pseudo=""
     CDS             <39863..40180
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /locus_tag="ETT65_RS06165"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="ETT65_06165"
                     /product="IS3 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="KCYDGTI"
     gene            complement(40237..40944)
                     /locus_tag="ETT65_RS06170"
                     /old_locus_tag="ETT65_06170"
     CDS             complement(40237..40944)
                     /GO_function="GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990206.1"
                     /locus_tag="ETT65_RS06170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_06170"
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="WP_002985031.1"
                     /transl_table=11
                     /translation="MTKKKGKLVLISLFVLAACLGAYSAMRQSHKTSNVSAETIASSST
                     RHFIDEIGPTASTIGQERDLYASVMIAQAILESSNGKSSLSQAPYHNFFGIKGAYNGSS
                     VTMSTWEDDGNGNTYTIDQAFRAYPSIADSLNDYADLLSSSTYIGARKSNTLSYQDATA
                     ALTGLYATDTSYNLKLNNIIATYGLTAYDVANSSAQETGLATSGYVWNEYRRNYTDAET
                     LAVDEAWAKRMTY"
ORIGIN
        1 ttagccaatc tacgccagtc atgccctctt tttctaaaat agcgttggtt cttgaaaagg
       61 gtttgctgcc aaaaaagcca cgataagatg acaaagggct tggatgaggg ctctcgatga
      121 tgtggtgctt tggattagta atgaaggctt ttttcttcct tgcataagct ccccacaaaa
      181 tgaaaactac agggatgtct ttctcattca gcactttaat aacagcgtct gtaaatggct
      241 cccatattaa gcctgcatgc ccattagcct ggcctgctgg cactgttaag caagcattca
      301 aaagcagaac cccttgacta gcccaagtgc ttaaatcatg atggtcacga ggaccaatgt
      361 catctgctaa ttcttttaaa atattaataa gggatggcgg agcagaaatc tcttctggaa
      421 ctgaaaatga taagccctgg gcctgtttgg ggccatgata agggtcttgt cctaaaatca
      481 acactttggt ttcttccaaa ggagtgactt gtaaggcttt aaagacattt tctcgttggg
      541 ggtagacaag accggaagca taggcttcat ctaaaaagtg attgatgcga ccatagtaat
      601 gctccggcaa aaatgatttg attttctcat gccaaattga atgagccata agattccttt
      661 ctaatcacgt cagtttctaa gttaaatacg atgtcctttt ctatctagtt taccacattt
      721 taaatagaaa gaccctgaaa atatgatatt tccagggtta atattcgttt tttacaggat
      781 attaaacaag tgctagctta ttttctaaga attcttggta acgttctaac aaaaaagcaa
      841 taagccaata gataaaggct actaaaatat acatggacat gtaatcccac tctctaccgc
      901 caataatttt ggcattttga aaaatatctg gtacggtaat catggcagct agcgacgaac
      961 ttttaaccat atcaataatg acattgccta gaggaggaac tgcaattcga aaagcttgag
     1021 gaagaataat tttcttaacc ataagagcat atggcaaccc taaagcctta gctgcttccc
     1081 actgtccctt gtcaatagct tctatagaag agcgaaaaac ttcagaaata taggcagcgc
     1141 taaccataga aaaaccaaga taagcgcaaa gtaaagctgg caattctaaa ccataataag
     1201 gcaacccgaa atacagaaca aagagcacca cgatcatcgg cacacctcgc ataatagaga
     1261 tgtacgctct aacaagataa tgaatcaacg gctgacgtga ccttcccaga agggctaggc
     1321 ctaaacctaa aaacagaccc gtaaaaaaac tgagcaacga aataccaagg gtataaggta
     1381 atcccgataa cacaaatcct aaactatctt tcattaatgg gatattaatc atgtggttag
     1441 gactccttta acatcaagta ttagttaacg tctttcgtat caatgacggg aatttttttg
     1501 tctttgccaa aaggttttgt caaatcttga ccagcatagt aggtttcaga gattttcttc
     1561 aagctaccat cttttatcat gtctttaata acagcatcta tttttttctt gaggctatcg
     1621 tcttttttgt tcataacaat tccttgttcg gttgggttgt actgaacatc gctcattttg
     1681 acatttagat ttggattttg agataacatg taatccacaa ataatttttg agctgggtaa
     1741 tcatttggaa tgaaatctgt tcgaccgtta gccacatcgt ttagataaac atctcctgta
     1801 acattatcgt aggtcaccag ttcggctccc tgtttttgcg ctactttcat gtattctgtt
     1861 ccagaagcac cagctgcttt ttttcctttc cagtcgctaa gatctttttt agccatgttt
     1921 gagctgccat cagcacggac aatcatgcct cctaccccgt atttataagg cgtagagata
     1981 ttgtattttt tctgacgttt tggggtaatg tcaaagttgt tcaaagaaat atccactcga
     2041 ccactatcaa ctgaggtaaa cgcttggtca aatcctgttt caacaaactt gactttaatg
     2101 ttaagtcgtt taccgatttc tttgaccata tctacttcgt aacctactaa ctcattatta
     2161 tcgttgtaaa aagaagttgg ctgataggtt cctggggtag ctacttttaa cacccctttt
     2221 tctttgatag tgtcccaact tgatttttga gattgatgtg gcgcacatgc tgccaataaa
     2281 aggctggcaa gtccgataga cagtaaagta actgatttct tcatagtaac tcctttatta
     2341 agataagaat agtataacat tttgattaag ttgtgttatc agtgagcgct caatctcttt
     2401 aaaaagttaa tctataatag ttaaactgtt ttataagatt attattgagg aatcttcaat
     2461 aatcctgctg cctcaaactg ctctgcaatt cctaataata ggtcctctct acctttggct
     2521 gcaattagtt gaatgcccat tgggagccct tccttagttt cgtaagtagg taaactaata
     2581 gctggctggc cagttagatt aggcagagct gtgtaaggat taatagccag actcttacca
     2641 aacatggttt cgaccaaatt gaattgctct tcactgctga aaatttcagc ttgagccaag
     2701 ttagccatga gtttcgaatc tgggacaagt tctccgtgct taggagctgg tgtgttggtt
     2761 gtgaacgtca acaacaggtc ataagtctca tgaaaactag ccatggttgc actgtacgta
     2821 tcccattttt gaaggacctg tgagtaacgc caagctggga tgtctttacc tgattggtaa
     2881 atagcccagg tcatggtttc catatcgtct ttggtcatcg gacgtccaaa agtgtcttca
     2941 atatcagcaa acatagcagc cgtttccaca ctattcataa tataataatg acgaatcact
     3001 tctgtcatat ttacaggaaa ctcttccaat tcaactagct gatgcccttg ttctcttagc
     3061 caagttactg cttgtcttaa agcttttgca gtatctaaag atactgggct accgtcactt
     3121 aaccgttgat aaaaagcaat tgtcaaggga cgttgtagcg attgataaat gctatctttt
     3181 gttaaggtgg ctagggggaa ggggctttcc atttgttcca tctgtaaata gtagagtaga
     3241 tttctagtat ctctaacgga tttggtcaag gcaaaatgaa ctgaggctcc ttgccagctt
     3301 cgataagaac caggtccgac aggcatgcgc ccacggctag gtttgagccc aattaagcca
     3361 ttaaacgagg ctggaattcg aatagaacca ccaccatcac tagcagttgc tagcgcacta
     3421 attcctgatg acactagagc agcagctccc ccagatgagc caccagcatt tcgtgtatta
     3481 tcctttggta aattcactgg tccgtgcaaa ctgctatcgc taatattttt aaagccaaat
     3541 tcaggcgtgt tagagcgccc taaaataata aagcctaaag cttctaatct tttcacaaat
     3601 aaatccgttt tagttgcttg atactcttta aacaatctgg aacctgaggt tgatgagtga
     3661 ccttttaatt cttgtcccaa atcttttaaa aaaagaggca caccagcaaa aggcagacct
     3721 gaaaaatccc tttgtttggc ttcttctagg gctgcttcaa agcgttctga ggtaatagca
     3781 tttaaggtag ggttcaactt tttagcctta taaatagcct gggttactaa ttctagtggt
     3841 gtggtctgac cagtctgaac agcaatagcc atagccgtcg catcttgata agtcatagct
     3901 actcttcctt tctaagatat gaatcctaaa acattctttt ttattaaagc acaaataaaa
     3961 gaaaaccacc attaaaaggt tagaaattag aatgtgatgt gtaaggagtg tagacaaaac
     4021 aatcaaaaca taacattttg aattggggct aaagagattt tttcattaaa aataaacctg
     4081 gctgatagtt ccttattgtt gccagtttac ctggtcttct ttaaattttt taagtaaatg
     4141 taaaccatca ttagtaatat agccttgcaa ctttgcaact gcaattagct cagtataatt
     4201 agaaagcgta atcaacttga taccagcttc tttaaaattc tgactagctt ttggtaactc
     4261 ataagtgaaa atcgcaacaa ctcccagaac gtcagctccc tcacgactgg ctgctgcggc
     4321 tgcatctagt accgaaccac ctgttgaaat caaatcttca atgataacca ttttttggcc
     4381 tttaagcaca cgcccctcaa tctggttgcc tgctccatga tcttttggct tactgcgaat
     4441 ataaacaaaa ggaagagtca ttttatctgc tataatggca ccgtgaggaa tacctgctgt
     4501 agctgtacca gcgatgacct caacttctgg gaaatgagcc ctgatagttt ccacaaaccc
     4561 attctcaatt aaatcacgag tcttaggata agaaagggtg acacgattat cagtgtaaat
     4621 aggtgattta atgccagatg cccacgtaaa agggtcttca ggctttaaat aaacagcttt
     4681 aatatcaagt aattgagttg caatttggct tgctagtgtc atttcttatt ctccttattc
     4741 ttctttaaca gacaagtgtt ggtttcctaa tcttatctgt tagcctgccc actcagcttt
     4801 tatggcttgg taagcagcca ctgggtcttt tgcctgggta attggtcgcc ctaccacaat
     4861 ataatcactt ccaatacgtc ttgcttggtt tggagtcatc actcgttttt gatcgccaat
     4921 attactgcct ttaggacgaa tgccaggagt taagcaagta aatcccgtag gcgtcaccgc
     4981 cttgatagct tctacttctt gtgccgaaca aaccacccca tctagctgag ctttagctgc
     5041 ccccttgctg taatgcaaaa cagactctaa aagactcgtt tgaatatttt gatcaccacg
     5101 catttggtct tcactggttg aagttagctg cgttaccgca attaaggtag ggccttgacc
     5161 tagtccttct cgagctgctt ttagcatctc tacaccacca gctgcatgaa cagttgccat
     5221 atcaatatct aattctttaa gaactgccat agcagcacga acagtatttg gaatatcatg
     5281 taattttaaa tccaaaaata cattatgccc taacgatttg atataccgaa caatatctgg
     5341 tccttgcgca taatataatt ccataccaat tttcacgtat agtttttctt ctgctggaaa
     5401 taagtctaaa aatgctttag tctcctcaaa tgatgaaaag tctaaagcaa taattgggcg
     5461 ttcttctttc ataacttatc ctttctataa tgtgtcaata tctcattaag caccaaaaag
     5521 cctcgctacc aaagaagcga ggctacagca aactaaaagg gaattccctt tttttatctt
     5581 gtataccttg tttgcctctc tggactcact taaaggtgtc taaatttaaa ctattatagc
     5641 ttttttaaaa caagatgtca aaactttttg ttatttgaac acatttttcc tactatatct
     5701 ttttttgtat acttacgtca actcatttta tcatttttac ccaatcattt attcaaactc
     5761 acctgtgggt atcttagggc tttggtaata ttttataaaa gcttcttctt caagattaac
     5821 cctctggata tgttcataga gcacatccgg aataggagct tccttaagtg acaaagcact
     5881 cacttttaaa gatgaaaaaa catcacttaa gaccccaaaa actcgaatgc gtttatctcc
     5941 aataataatt tgaaagactt ctttggactg gcataaatct atcagatgat ccactccttt
     6001 aatccaatta tcgacaatat ccaaagtttt gttcatcaac ttaaaagctg attcttcata
     6061 ccaaaaggta gactcaatca agcgttgctg catatccaag gtatcaatgg ccgcaacaat
     6121 atctcccaac tcagactgta ctaaatgagc tggaaattcc cctccaagta tagaaggagt
     6181 tcgttctaca agcttcagtt catctcgaaa aagagtcaaa tagtggatac tgaccaataa
     6241 cttttggatt aagatttgat gactattttg ttcagtaaca ttcacacgac caccaccctt
     6301 tgattagaaa aatacctatt tgttaatact attaatataa cacaagaaaa ataaaagggc
     6361 aatgaaattg atagattcaa ctctcaaaat tgaatcatat ttatcctagg ccatattgag
     6421 aaaagactcc agcgcttttt caaagttcta aacccatgat gacgtttgtg cttgcgtctt
     6481 tatttttttt gagctagact gtacttatga gaattcaaca actgcattat attatcaaaa
     6541 ttgttgagtg cggctctatg aatgaagctg ctaagcaatt atttatcaca caaccaagtc
     6601 tatccaatgc ggtcaaggat ttggaaatgg agatgggcat taccattttc aaccgaaatc
     6661 ctaaagggat caccttgaca aaagatgggg tggaattttt atcttatgct cgccaaatta
     6721 tagagcaaac atcactgtta gaagaccgct ataaaaacca caatactggc cgagagctct
     6781 ttagcgtttc atctcaacat tatgccttcg tagtcaatgc atttgtctca ctcctcaagc
     6841 ggaccgacat gactcggtat gaactctttt tgcgcgagac aagaacttgg gaaatcattg
     6901 atgatgtcaa aaactttcga tctgaaattg gtgttctctt tatcaacgac tataaccgag
     6961 atgtcttgac caaattattt gatgacaatc atttgaccgc ctctccatta tttaaggcac
     7021 agcctcatat ttttgtcagc aaatcaaatc ctctagcaac taaaagccta ttaagtatgg
     7081 acgacttgag cgattttcct tacctgagct atgaccaagg gattcacaac tccttttatt
     7141 tttcagaaga gatgatgtcc cagatgcccc acaacaaatc aattgtggtc agtgaccgtg
     7201 ccaccctctt taacttaatg attggtttag atggctacac cgttgccagt ggtattctaa
     7261 atagcaatct aaatggtgac cagattgtgg ctatcccgct agatgtccct gacgaaattg
     7321 acattgtttt tatcaagcat gaaaaagcca acttgtccaa aatgggggaa cgttttatcg
     7381 aataccttct cgaagaagta acctttgatt aatgtctttt tcaatcgtca tactaaaaaa
     7441 acacggtagt aagacctgta tcggtcaagt tatcgtgttt tttgataaat atcagacaat
     7501 agattgtctc caaaggctca actccttttt aataatggca ttcatgtcat caaagtaaaa
     7561 aggctcacgt cggtagatta caccagaaaa agtcgccaag gtgataatgt tttccaaaaa
     7621 agcctgagaa gaaaaatgag tggtgcgatg cagttcctct tcatcaaaag gcttaatcaa
     7681 atgagccaga ggattacgga cagccttttc aaaatgtcgt aacaaaaaaa ccaagtcctt
     7741 gatttcctga ggtaaggagg tcaacgtcaa catgtctgct aagcttttgg tcgtcacatt
     7801 gcgagactgc ttttgagaca ggtaagcctt gaaaacctcg tgatcagatt ccaacatggc
     7861 ctgaaaatgc caggtatcat attggtcatt ctttgtatca aaaatataag ccttgaagtt
     7921 tggaatttct gacgtgatta gtctgagaaa aagtcggtaa agaataggcg acactgacct
     7981 gacgaaatca ataatagcac cgttttttac tttaacttct aaatccaaaa tgtaattggc
     8041 aatctgctca tcttcaagcg attggttaat ccataatgaa cagtggtact ggtcttcaat
     8101 ggtccgattc tctgctgcat gttccgccag aaaggcaagg ttcaattctc tgcgctcttt
     8161 taacatctct agtaaataga gagcagtttt agggatattt ggcaaggctt tagcaattct
     8221 aaaggcgtga ttataagcat agacatccaa aaggatgtct agcgtttgat tattagtcat
     8281 tggcaattaa ggtttccaag ccgaccttca tcatatcagt gaaagttgtt tggcgctctt
     8341 cagcagtggt gtcttctgtt gggttgttca aattatcaga aattgtcata ataccaagag
     8401 ctttgacatg gtgctgagca gctaaatagt aaagagctgc tgcttccatt tcgatggctt
     8461 taacacccaa tttaccaaga gccatattac gctcaggcat gttagtgtaa aagacatcag
     8521 aagaaagcac attcccaacg tgagttgtta ctcccatttc tctggcgata tggtaagcct
     8581 tgtcaagtag accaaaatca gcaatttgtg ggaaatcaaa ttctggaaag tcattacgga
     8641 taatatttga gttggttgct gctgcttggg caagcaccaa ttcacgcaca tgaacttctg
     8701 ggtcaatcgc acccgcagta ccaacacgga tcaatgtttt gacaccgtaa tcaacgatta
     8761 attcacgagc atagatagag atcgaaggca tccccatacc agttcccatg acagaaacgc
     8821 ggtgcccttt gtaagttcct gtgtagccaa acatgttacg cacttcgtta aaacacactg
     8881 catcttctag gaaattttca gcgataaatt tcgcgcgcaa agggtctcca ggtagaagaa
     8941 ttttatcagc aatatcacct tttttggcag aaatatggat agacattatt aagatattaa
     9001 aggcgacaaa gaacaaagta aaaataggaa actgacgacg catcccagat gctagacagt
     9061 ttatcttttt tacacagttc tccgcccgta ttcaattcaa tgaatacagt tagccctacc
     9121 tttcctttta ttttgtagaa ggtcagaggg cggacagaaa gcaactgaaa tttagggaac
     9181 taacgccatg tgtgagcaca aaagttagtt tatctagttt ccgagctttc cgcccgtatt
     9241 caattgaata caaccccatt cctttcataa ttgatattga atagaagaag agagctaaaa
     9301 atcgagttca aataataaag gactaactct ctttccttta ttatttaaaa attaatacga
     9361 agaaatgttc gagtccatgc ttaatttaaa ccgaatacgt ctctttccct tcgttggtta
     9421 tgttagttag aaaagctaga atctgagttc aacattcata gaactcacat cccgtgatta
     9481 ttttttgatt tttttattgc gaacagatgt gccaaactga cgacataaaa taacattcct
     9541 gtaataatgc tccagttgat tttgttcgtc ctacaactca gctaaaatag ctttaacaag
     9601 acctttgaaa tcttctttaa tatgttcagt cacttcaaca acttcttcgt ggttcaattc
     9661 tgattggaaa ccagctgcaa agttagtgat ggctgaaatg ccaagtactt taagtccaga
     9721 atgagcagcc acaataactt ctggcacagt tgacatgccg acagcatctg ctcctaatac
     9781 tttgaaagca cggatttctg ctggtgtctc ataagttgga ccagttaagc ccatataaac
     9841 accatcttct agtttgatgt tcattttttc agccacttca tgtgccttat tgcgataaac
     9901 cttagtatag gcatcagaca tatcaggaaa gcgtggacca aactcgtcca agttttcacc
     9961 gattagtggg ttatttccgg tcatattgat atggtctgtg attgccatca aggtacctgg
    10021 gccgtagccg ataccaccag ctgcatttgt gacaagaacg ccttcacatc ccagagcttt
    10081 catgacacga acagggaaag tcaccacttc aagcgggttt ccttcgtaaa aatggaaacg
    10141 accttgtagg gcaagtactt tacgaccagc taaatcaccg tagactaatt ttccagcatg
    10201 gccaacaact gttgatttgc cccagtttgg aatatctgca taatcaataa caacaggatt
    10261 ctctacttct tcagcaagtt caccaagtcc tgaacccaga attaatccaa attctggagc
    10321 ttcaattcct ttagcaacta aaaagtcttt tgtttcgtta attttagtca tcaatgacat
    10381 ctttttctcc ttttacctca atagggttca cactctcgcc atcctctttc ataataagga
    10441 ctaggcaggg gaacaggaag aatatccagt aaggtctcag aaggacggca aagttttact
    10501 cctttgcgag tcacaacaat aggacgattg atcaaaattg gatccgccaa catggcatta
    10561 ataatgtctt tctcagctac tgcttgattt gctaatccat gagcctcaaa ttcaggaaca
    10621 ttggttcgca agagttctcg cgcagagatt cccatcgatt gtaagagctc aattaaagtc
    10681 tcccgattag gtggcgtctg caaatactca ataatagtag gctcaatacc tgcatggcga
    10741 atcatggcaa gaacattacg tgaagtgcca cagtttggat tatgataaat cgtgatttct
    10801 tccattatca actaattttc ttattttaag tgaccaagga atgactcccc aatcatggct
    10861 gtatcaactc caaaattttc tgcaacagtt gctgaaatat ccgcaaaatg cccttgtgga
    10921 ataagaccat ttccagtaaa ggatacagag taggcaagca atggaatgta ttcacgagtg
    10981 tggtcggtgc ctgcataggt tgggtcatta ccatggtcag cagtgatgag aagcaaatcg
    11041 tcttctttca tatttgcgat gatttcaggt aggcgattgt caaattcatg caagcagtcg
    11101 cgataaccct ctgggtcacg acgatgacca aagttggcat caaaatcaac gaggttagta
    11161 aaggagaatc ccttagtaaa ctcaggtaat tgaagagtct taataagcgt gtcaatacca
    11221 tggctgttcg acttattgtg tcccatgtcg tttgtaatac ctgaaccatt aaagatgtca
    11281 ttaatcttac caacggcata agttgggaca cctgcgtcag ccagtttgtt caaaacggta
    11341 tcttggaaag gagacactgc atagtcatga cggttagccg tacgtgtaaa gtttcctggt
    11401 tcgcctacat aaggacgcgc aataatacgg cctaaaaggg cagggcgttc aagcgtgatg
    11461 gagcgagcat attcacaaat cttgtaaagc tcttccacag gaataatgtc ttcatgggct
    11521 gcaatttgaa gcactgggtc tgctgaggtg taaacaatca actcacctgt ttccatttga
    11581 cgcggaccaa aatcatcaat aaccgcagtt ccagaatagg gtttattagc ttcacgaata
    11641 attttgcgac ctgagaattc ttcaatctta gttaaaatct cttctgggaa accattccag
    11701 aaagtgtcaa aaggttccgt aatgttcaag cccataattt cccaatggcc tgtcatggta
    11761 tcttttccaa gagatacttc ttccaattta gtcacgtaac cagtaggatt gtcttctgtt
    11821 ggaacagttt ttagtggtat tggacgagaa atgtttccaa gtccaatttt tgccatattt
    11881 ggaaccgata agcctgctgt ttctgaaata tgaccgaggg tgtcagaatc tgtatcagct
    11941 acaccagcat taaagaattt gtcagcatct ggtgctgcac caataccgac agagtctaaa
    12001 acaaccaagt gaatacgatt aaattttgac ataagtctcc aatctagggg aggttacggt
    12061 tgactcccca atacctataa aatatattaa cactgttata tgctaagact agcctgcttt
    12121 aggcgcttct aaaacagtaa cgccgtcttt actagcaaca atcaccttat caaccatacc
    12181 attaaagaga ccgtgttcca caacaccaac tgttccatct agcaggtgac caaaagcaac
    12241 aggatcttta atacaaccca aatcaagatc aataatatag ttttgcatgt ctgtcaccaa
    12301 acgactatca cctttcatac gaaaagacgg tttgtaacca gctttttcaa agacacggaa
    12361 caaacgatca gcaccgtatt gaacgacttc gactggtaac ttaaaggcac ccagatgctc
    12421 taccatttta gaagcatcaa caacccagat gtattctttt gttggtgttg caacaatttt
    12481 ttccattagt aaggctgcgc cgccaccctt gattccattg aaatccttat ccacttcatc
    12541 agcaccatct acggtgaggt caatgctatc aatatcatct atcgatttta aaggaatgcc
    12601 taatccttct gcttgcttgc tagtcacact tgacgtagtc acaccaacca cttgcagtcc
    12661 ttcttgcttt acgcgacggc caatttcctc aacaaaatag taagccgttg acccagttcc
    12721 aagcccaatg gtcatgccat cagtcacata ttgcgcagcg gtaacaccgg caattttttt
    12781 gagtgcttcc atgattcccc cttataatag aattgcgtct tagcacttta ttataccatg
    12841 aaagcgccaa cttgttaatg aaaacatttg tttttctctc attgacagcc taagtactat
    12901 agaataggat gatcttttta aaacttatga tttattctaa agtcatcata taagcactta
    12961 cttttcgtgt ttatttagct ttttgaaaat caagtgtttt tgtttgacct ttactgacct
    13021 tttgattata ataatactat aagatgagta aaaataatgt ctgaatcatt ttattagcaa
    13081 agggtttcct atcatgtgaa atcctaacaa cgattctgcg actgcttaca aacatcttat
    13141 agtctatttt ttattgcgag gtaactgata tgacacattt ttctggtaaa gatccttttg
    13201 taaatatgga tgatattttc aaccaattaa tggcaaacat gggtggttat cgtagcgaaa
    13261 atccccgcta tctcgttaac ggtcgcgaaa taactcccga agaattccaa cactatcgtc
    13321 aaacaggaca actccctgta gcgacaacca aagcaacaaa ttctcaaatg ttaacaccta
    13381 aagctgatag tgtattgact caactcggaa ctaacttaac acaagaagct cgtcaagggc
    13441 atcttgaccc cgtcattggt cgtaacaaag aaattcaaga taccgctgaa atcttggcac
    13501 gacgaactaa aaataatcct gtccttgtcg gagatgctgg tgtcggtaaa actgcagtca
    13561 ttgaaggttt agctcaagcc attgttaatg gaggtgtccc agctgctatt aaaaacaagg
    13621 aaatcgtatc aattgatatt tctagtcttg aagctggtac acaatatcgt ggttcctttg
    13681 aagagaccat tcaaaacttg attcaagaag taaaagaagc tgggaatatc atcttatttt
    13741 ttgatgaaat tcatcaaata gttggtgctg gtgccacaag cagtgattca ggctcaaagg
    13801 gacttgcaga tattcttaaa ccagccttgt cacgaggaga attaacactg attggtgcta
    13861 ctactcaaga cgaataccgc aatactattt taaaaaatgc tgctctcgct cgtcgcttta
    13921 atgaagttaa agtgaatgca ccatcagctg aagatacttt tcacatttta atgggtattc
    13981 gtaatcttta tgaacaacac caccatatta cccttcctga taatgttcta aaagctgctg
    14041 ttgattattc tattcaatac atcccacagc gtagcctgcc agataaagca attgacttac
    14101 tggatatgac agctgctcat ttagctgcgc aacacccggt cactgactta aaaacactcg
    14161 aaactgaaat agctaaacaa aaagagaggc aagaaaaagc tgtcgccaaa gaagactttg
    14221 aaaaagcttt agcagcaaaa acacggattg aaacattaca aaagcaaatt gagcaacata
    14281 accaaagcca aaatgtcact gctacagtca atgatatcgc agagtctgta gagcgcttaa
    14341 ctggtattcc tgtctctaac atggggacta atgatttaga aaggctcaaa ggaattagca
    14401 gccgcttaaa aagccatgtc atcggacaag atgaggctgt cgcagcagta gcacgtgcta
    14461 ttcgacgaaa tcgagcaggt tttgatgatg gtaaccgtcc aataggttct ttcctttttg
    14521 tgggtccaac tggtgttggt aaaacagagt tagctaaaca attagcactt gatttatttg
    14581 gttccaaaga tgctattatt cgacttgata tgtccgaata taacgatcgc actgctgtgt
    14641 caaaattgat tgggacaacg gctggttatg ttggctacga tgataataat aataccctaa
    14701 ctgagcgtgt tcgtcgtaac ccttatgcta ttgtcttact agatgaaatt gaaaaagctg
    14761 atcctcaaat cattacactt cttctacaag tgttagatga tggacgattg acagatggac
    14821 aaggaaatac tattaacttt aaaaataccg ttattattgc tacatcaaat gccggttttg
    14881 gccaacaaga tacggaaact tctgagtcta acattatgga tcgcattgca ccttatttca
    14941 gaccagagtt tttgaaccgt tttaatagta tcattaaatt taatcatctg caaaaagaaa
    15001 atttagaaga aattgttgat ttaatgctag ctgaagtaaa tcaaaccacc gcaaaaaaag
    15061 gtattagttt aacgattgct gatgacgcta aagctcattt gatagattta gggtacaatc
    15121 acgctatggg agctcgtcca ttacgacgta ttatcgaaca ggaaattcgt gaccgtataa
    15181 ctgattatta tcttgaccat ccagaagtca aaaaacttca ggcaatccta aaagaaggac
    15241 aactagtgat caggcaaaac gatcagtaat aaacttcttc aattgaataa ttttcaaaac
    15301 atgaaaaaat ccgtcttgtg actacgttat acacttgacg gacttttttt tagcgctttt
    15361 ttaaaaataa ttttttcatc gcctaataac tcaagtttct ttccaaatct ggtgtaatca
    15421 aaataaccat taggtgtgag caatcctttt gaaaaagaag tatgtcccgc tgctacttct
    15481 tctttgatat caatggtgtg caaaatacga ttaacttttc ctttgagaac aacagcagat
    15541 aaatgtcctg ttttttgatt atatttgcct ccgatctgag aagctaattt ctcaaaagct
    15601 tgatctaaaa tcatttctaa ttcatggcta gctggcatac tattctcaat aatttggcgt
    15661 tctttactac tcaagtcacc aacaactaaa tgattttcct ttaatgtctt taataattca
    15721 ttttggtgat aagcagctaa acgtttgaca aaaatgtctc gttcaacttg aacactaaaa
    15781 ctcaagtcaa cgttgttatt tttaactgtt agtatcatct gagatgacgt taataaacta
    15841 tcatcaataa gagggctctg atgcaaacca gtaagacgtt tagcaaaatc atcgcctaac
    15901 ttctgatcaa tgcttgttgt tcgccagata ccttcaatag agctattacg ataccgaaca
    15961 ccaaaaagta cagcaagcaa gataagaaaa ataataaata caaaaagggc attgcattga
    16021 tggcataaca atgactttcc tttagagcgc ccttgggcta cttgtgtcat gactcatctc
    16081 cttaatataa aatactagca tgtcatcatt aaggcgtcaa gtaaaatcgg taaacctaac
    16141 tatgattttt tatgttttcg ataagaaaaa caccctctac tgagaatgtt ttagcataga
    16201 taaatcaaca cctatcgcta gacctgctct aaaatagcat cccaagaatc atcgatacca
    16261 atacgttcta ccgaagaaaa tactataaaa gtatcagatt tgtcaaaatt caaagctttc
    16321 ttgaccacag actcatgttt gttccatttg ccacgaggaa tcttatctgc tttggttgcc
    16381 acaacaataa caggaatgtc atagtacttc aaaaagtcat acatctgaat atcttctttt
    16441 gaaggggcat gacgtaaatc caccaaactc acgactgcac gcagattgtc tctgctggtt
    16501 aagtattctt cgatcatctt tccccatttg gcccgttcac ttttagaaac cttggcatag
    16561 ccataaccag ggacatccac aaatctaagc ttgtcatcaa tattgaaaaa atttaatagt
    16621 tgggtttttc ctggcttgct tgaggttctt gccaaatttt tgcgccccaa tatggtatta
    16681 ataaaacttg atttaccaac atttgaacgt ccagcgaggg caatttctgg caaatcatct
    16741 tgggggtaat gagatttatt ggcagcgctc aataaaattg atgcgttatg ggtatttaag
    16801 acttgttctt cagccattat ttctccttaa gcggtctcta aaacgggttt tgacttgcct
    16861 tcgacagcag ccttggtgat acgcactttt gtgacatctt cttggcttgg aatttcaaac
    16921 atgatgtcta acatcgtttc ttcgataata gaacgaagac cacgtgctcc tgtcttacgt
    16981 tcaatggctt tattggcaat ggcttctaag gcttccttat caaatgccaa ttcgacgcca
    17041 tcgtaagaaa gaagagcctg atattgcttg accagggcat ttcttggttc tgtcaaaatt
    17101 tgaatcaaat ctgatgtgtt tagttgttca agggctgcca caactggtaa gcggccaata
    17161 aattctggaa taagcccaaa cttttgaata tcttctgaaa taatttcttg catataagaa
    17221 gcattgtcat caattttacg gctgttttga ccaaaaccaa taactttttc acctaaacgt
    17281 tgtttaacaa tctcctcgat gccatcaaaa gccccgccaa caataaacaa gatatttttt
    17341 gtatcaattt ggatcatttc ttgattaggg tgcttccgcc caccttgtgg gggaacactt
    17401 gctaccgtac cttcaataat tttaagaagg gcttgctgta caccttcacc agatacatca
    17461 cgtgtgatag atacgttctc acctttttta gcaatcttat ctatttcatc aacataaata
    17521 ataccacgct ctgctcgttc gacattatag tcagcagcct gaatcagttt gagtaaaata
    17581 ttttccacat cttctccaac ataccctgct tcagtcaaag aagttgcatc tgcaatagca
    17641 aatggtacat tgaggctttt agccagagtt tgtgctaaga aggtttttcc tgaacctgtt
    17701 ggtccaatca tcaaaatgtt ggacttttgt aaatccacat catcgtcatc acgactttct
    17761 gtaaacgaga cacgcttata atgattgtac acagcaactg ataaagcacg tttagcacga
    17821 tcttgaccaa ccacatattg atttaaaaca tcaaggagct cttttggttt tggaacttct
    17881 gtcaaatcgg caaggacttc ttcagccaat tcttctttta taatttcttg tgataaagct
    17941 acgcattcat tgcagatgaa aacattattt cctgcgataa tttttttaac gtcatcctgg
    18001 cttttaccac aaaatgaaca gtatacttta atatcgttag ttctacttcc tgccatttct
    18061 tataattctc ttactttctc ttatctttta ctgaatttta atattagtca atgtgttgta
    18121 ttggtttttg gtgattcttg cttgatagct aaatcttcac cagtgctgtc tttgcaagtc
    18181 gcatctcaaa acaatgtacc atagaaggcg tgaatactat taaccagatt agtaaacgca
    18241 tttaataaga acagacttgc taagccataa cgattctttt taaaagctgg gatggcacaa
    18301 agaacacaaa tcacgcacaa aaaagccgta aatactccaa aaatactacg ttgcatcgct
    18361 tattatctcc tcagactatt tgtgttttaa agcagtaacg gtaaaatcat aaggattttt
    18421 agcgtctcga gcatagaacg tttggctttc ttgcgtgaaa tgactaaaat ctagatttgg
    18481 tcggtaggta tctcctttaa aacgatgatg gataactgtt tttatgatac gatcgaaata
    18541 accattaaac gcttctaaaa ccttattccc accaatgata taaagtgttt tatcctgcgc
    18601 atggtaccac tccaagactt tttcaatact agtcattgtc aacacctcat ctacttgata
    18661 atctctattt cttgtcatga caagggtttg acgttgagga agtcttttgc aattcattcc
    18721 ttcaaaagtc acacggccca ttaagattgc ttgatgtagc gttgtctttt taaaatgttc
    18781 taactctttt ggtaaatacc atggtaactt acccgcaaca ccaataagcc ctgcttcatc
    18841 ctctgcccaa atagcaataa tttcctttgt cattaattat ttccttcatt ttaaactcta
    18901 tttattttac caaatttatg aacaaaatgc tcacaaaaaa tctaaataaa gtttaaatag
    18961 caaggtcaaa gtgcaactga ggcttcactg gatcataatt ttgtaattca aaatcatctg
    19021 gtttaatatc aaagaaatta gtcccatctg gaacatttaa aacaagctta ggctgactgg
    19081 caactggctg tcgttttagt aattcttgag cctgatcaaa ttggttgtca taaatatgta
    19141 aattgttaac aaaataaaag aacttaccta ttttccatcc aaaatgttta gcaatcatca
    19201 tctgcaaggc aacgtattgc atggcattga tgtgatgagc aactaatatg tcattagaac
    19261 gttgcgtcaa actagcatct aaataaagat cttcccctac acgtctaaca tcaaacatga
    19321 tttgaaaggc acatggcaac aacccttttg tctcctcaaa tgcttcatag tcccagagag
    19381 aaatgacatt acgacgattc caaggatttt ctgctaattg ctttagtatt tttgagatga
    19441 tatcatgttt tttgactaca gcaccataac gttgtccaat agtacgtgtc tggtcaactt
    19501 cccattcatt ccaataatga acattatatt tagcttctag cacatctaaa ctgttagact
    19561 gatcttgata tatccaaaat aattccttta tagcagattt aattggaatg ggtcgtaaag
    19621 ttgtgatggg aaactctcct ttagctaaat catattcagc aaacgcccca gtaatatact
    19681 tagaatgagc tgttcgacca tctttatatt taggacgtgc ttgctcactc aatgatcctt
    19741 catttataat tttttgaata ttagctttaa aaatctggtc agcttttgtc atctctaata
    19801 acctttctgt aagcatactt catactattc taactaattt taccaaaaaa taccagaata
    19861 aataaacatt cgaaaaactt catgtggtca tgaacatttt aactattaaa ggataaaaca
    19921 aataacctta tcagtctaat tttgcagtaa aatgtgatag aatgggtaag actataaaaa
    19981 taactaaaag aaggacaaat atgacaattg gaattgataa gattggtttt gcaaccagtc
    20041 aatatgtctt gaaattggaa gatttagcgc ttgcacgcca agtggatcca gcaaaattta
    20101 gtcaagggct actcattgag tcttttagtg tggcaccaat cactgaagac attattactt
    20161 tagctgcttc tgcagcagat caaatcttaa ccgacgaaga tcgagctaag attgatatgg
    20221 ttattttggc aactgaatcg agtactgatc agtcaaaggc atcagctatc tatgtacatc
    20281 acttagttgg tatccagcct tttgcacgtt cctttgaagt aaaacaagcc tgctatagcg
    20341 caactgctgc tctagactat gctaaactgc atgtggcttc taagccagat tctcgtgtcc
    20401 ttgttattgc tagtgatatt gctagatacg gtgtaggatc tcctggggaa tcgactcaag
    20461 gctctggtag tattgctctt ttggtaactg ctaaccctcg tattcttgct ctaaataaag
    20521 ataatgtggc tcaaactagg gatattatgg acttttggag gcctaactat agtttcacac
    20581 cttatgttga tggtatttac tctaccaagc aatatctcaa ttgcttagaa accacgtggc
    20641 aagcttatca gaaaagagaa aaccttcagt tatctgattt tgctgcagtt tgtttccata
    20701 ttccatttcc caagttagcc ctaaaaggtc taaataacat tatggataac acagtacctc
    20761 ctgaacacag agaaaaacta atagaagcct ttcaagcttc tattacttat agcaaacaaa
    20821 ttggaaatat ttatactggc tcactttatc taggattgtt atctttactt gaaaatagta
    20881 aagtattaca atctggagat aaaattggtt tttttagcta tggttccggt gccgtaagtg
    20941 aattttattc cggtcagtta gttgctggat acgataaaat gttaatgact aatcgacaag
    21001 ctttactgga tcaacgaaca cgtctttccg tttctaaata cgaagacctt ttctacgaac
    21061 aagtccaatt agatgataat ggtaatgcca attttgacat ttacttaact ggaaaatttg
    21121 ctctaacagc catcaaggag catcgaagga tctatcatac caatgacaaa aactaatctt
    21181 aactggagcg gtttttcaaa gaaaacattc gaagaacgcc tccaacttat cgaaaaattt
    21241 aaactactta atgctgaaaa cttaaatcaa ctcaaaacag acgtgctttt gcctatccaa
    21301 acagctaatc aaatgactga aaatgtctta ggacgattgg ctttgccctt tagcatagct
    21361 cctgattttc ttgtcaacgg ttcaacttat cagatgcctt ttgtcacgga agaaccttct
    21421 gttgttgctg cagcatcttt cgcagcaaaa ctaatcaaac gctcaggtgg ttttaaagct
    21481 caaaccctaa accgacaaat gattggtcaa attgttcttt atgatatcga ccaaatagat
    21541 aacgctaaag ccgccatcct tcataaaaca aaaaagctaa ttgcattggc aaataaagct
    21601 tatccttcca ttgttaaaag aggtggaggc gctagaacca ttcatttgga agaaaaagga
    21661 gagtttttga ttttctatct gactgttgat acccaagaag ctatgggagc aaatatggtc
    21721 aatactatga tggaagctct tgttcctgat ttaacaagac tgtctaaggg gcattgtcta
    21781 atggcgattt tatctaatta cgcaacagag tcgcttgtta ctactagttg tgagattccc
    21841 gtgcgccttt tagatcgcga taaaacaaaa tccctacagt tagctcaaaa aatagagcta
    21901 gccagccgac tagctcaagt agatccttac cgggctacta ctcataataa aggtattttt
    21961 aatggtattg atgcagtggt aatagccaca ggaaatgact ggcgtgctat tgaagcaggg
    22021 gcacatgctt atgcctcaag aaatggtagc tataaaggac ttagtcagtg gcattttgac
    22081 caagataaac aagttctgct tggccaaatg accctcccta tgcctattgc tagtaagggg
    22141 ggatctatcg ggcttaaccc tactgtttct atcgcacatg atcttcttaa tcaacctgat
    22201 gccaaaacgt tagcccaatt gattgcatct gtggggttag ctcaaaactt tgctgcacta
    22261 aaagctctga cctcatctgg catccaagct ggtcacatga aactacatgc gaaatcatta
    22321 gctcttttgg cgggggcaac ccaagacgaa attgctcctt tagttaatgc tttactggct
    22381 gataaaccaa taaatctaga aaaagcacat ttttacttat ctcagctaag acagtcttag
    22441 atttaaacaa ctaatataag gcaatcaccc atgtaaacaa ttggtttaca tgggtgttta
    22501 atctttgttt ctatacatac aagtcttaga aatagtctcc ataaaatact ctatttactc
    22561 atctactcta ttctgagttt gatgaggtat ttataaatat tttatattat gttctaaaaa
    22621 agctctatca tctttgtagt aggtgacact attgtagagg tgatgaagcc taattgacct
    22681 gctgcaagcg tccatatagt aagtagtcga ctccctttaa ttctttaata gttttacagt
    22741 caagagcaca cataatgatt tttaattctt ctttccagcc gttaacgata gcaatcacac
    22801 gctcggttgg gtatttttcg accaattcta aaacggtgcg tgagagtccc actgcacgtg
    22861 ctcctaggac gaaacattta atcatgtcca aggggtgtct gacaccaccc gaagctaaga
    22921 tttccacttg atccatcagt ccttgtgcat ttagcaagca ctgaacggtg gtttgtcccc
    22981 aatcgtttaa gtaagagcgg tctcctcctc tttgattttc aatataggca aatgaggtac
    23041 ctcctcttcc tgaaatatca aaggtttgaa tgcctaggtc atgtgctagc ttgatactat
    23101 tgacatccat gccaaaacca acttctttga gaatgacagg aactggtatt tgactagcgt
    23161 attcagcgag gtgttttttc caggtatgaa agacgcgctc accctctggc atcagcaact
    23221 cttgcatcac attcacatga acctgtaaaa agaggggctg catttcttga accgtttgtt
    23281 gtcctagcgc cacaggttta tctagaccaa tattcgtggc tagtttcaag ttatctgcca
    23341 cctcatgtaa acgataggaa tcgtcgttag gattttttaa agcagcgcta taagaccctg
    23401 tcaccatgac aatccctgtt gctgctgcta ctttggccaa tttttcattg acagctttgc
    23461 ctttttgact tcctcctgtc atggcattga tgtaaaaggg aaagtcgaag tcttgcccgg
    23521 caaaatgagt actgagatca atatcagaca aatcatagct aggtaaggaa tgatgtatga
    23581 gttctatgtc atcaaaagca ttataaggcg attggtactt gagggcatat ttgatgtgat
    23641 catctttacg gttggtcatt ctctccccac ctttcttgat aaagtaatgc gatatcagct
    23701 tcttgccatt tggaaataag ggtatctctg gcattctgat taaaggcaag cgcgatgcca
    23761 caatctccac caccagaacc tgaagattta gcaacagcat cttgcttctg acaagcagct
    23821 accaaggtta ctagcttagg atggtagata actggatgaa gcttttttag gagatgactt
    23881 gctcctgcta aacttttctt gagttcttcc ttatgacctt cttgcaaagc taccatagct
    23941 gattgcgtta gctggtaact tgttcttaag aaagctgggg taatgctcgc tgtcacttgt
    24001 tgaatcatct gccttgaaat agcaggtatt ttagtccagc caaccaaaaa gtcacaaggc
    24061 agggctggtt gaatgacttg gatatggtaa ccccaatctt tgacgagaag tttttttaag
    24121 ggcatggtct gcagccagtt actgacctgt tctcggtcaa aggaggtata ggcgactaaa
    24181 gtctggtaag cgatacaggc aatatccccc atagacccat tatctccttg cttaagcaag
    24241 gtataagccg ctagtttaaa gagtaactct ggggttaaag tgatctgata ataggccgat
    24301 aaggccttta aggttaagag ggtgacacta ccacttgaac caatgccaaa ttttttgcca
    24361 tcgcgctcca tttttcctgt tatgattaag gaaaatggct ccagttggtc aattgactgt
    24421 cctagataat cagcaaaggt tttaaccgtt gcttgaatca gtgcataaga ggcatcgggt
    24481 gtcatgcccg ctttatgggc aaacatatct gaagctaatt gaatatgggc tgctgggcta
    24541 atttctgctg tcatcatcag tggaataaag tgaattaagg ctttttgtcc tggtgttaag
    24601 atagcatatt cgcctgtgag gtatagtttc ccacctgttt gcacacaata attagacatc
    24661 tggtaaatcc tttgtttttg aaacgataat acggtagttc ttgccaagtc gttctgctag
    24721 ttgagccaag tctttatcta aacataggac cttcacattt ggacctgcgt ccatggtaaa
    24781 ataacaagca aaaccttctt gacgcagttc tttcacagcc tccatagcct ggtaagactc
    24841 ttttgttagg taagaaaagg gaggattggc tgtctttgtc gtggcatgca tggccaaggc
    24901 attagcttct gttaactgac caactttctc aaaattatta gttttgagat aggtaagcat
    24961 atgttggtaa tcaattgccg attgttctac ccattcatca aatgtagttg aggtatcgcg
    25021 gcataacttc atgccctctc ggctagaaat tggctttttc gcagcattta agaccagcat
    25081 aatcatggcc attttcaagt cagtctcaac cttgtaaata gcaccactat ctttgtccca
    25141 agcagcaact gggccaaaaa aagaacgaga agatgatcct gaggcgaact tagccttttg
    25201 agctaaagct ttctgatcta gctgagtgtc aaataattga tcacaggctt taaccaaggc
    25261 tgataagcca ctggaacttg atgataaacc tgcagctgtt ggcatattat tttgagtttc
    25321 catctttaca aaagcctgac caggttggcg aaattggtca atgatagtag aaattttggt
    25381 atgttcttcg tcattttgca agacaccgtt aatgtaaaac tgatcactgg ttgcagtatc
    25441 tggtaagaag gaaacgctgg ttgtggtgaa catgttttcc aaagtcaaag aaatgctaga
    25501 ggtcgaagga atcatcttag cttgattctc ttttccccaa tatttgataa tagcaatgtt
    25561 agcataggat gttacggtta taacatttgg atccacgtgt ttacggctcc ttcttctttt
    25621 aatctgtgac tgattttttc ggccatgtct ttggtatctg ctagggcaat catacagcca
    25681 cccaagccac cgcctgtcat cttagcgcct aaagcacctg ctcttagggc agcctccaca
    25741 agttggtcag ctttactgat gctaacgcca atggccttta aagcagagtg cgcttgtgtc
    25801 atgagctgac cgatagccac cttatttttt tggttaatcg ctctttcaag ggcttgtgtc
    25861 aaagctccta gtttagccag atagggcaaa ttcgtttcct caaactgtgc taccttattg
    25921 acggcctcac gtgtatgacc gtgaatccct gtatctgcaa tgataagata accatttaag
    25981 gcgatttcga tagtttcaaa gccaatgttt cggataaact taatggcatg gtcactaagg
    26041 catgtcttgg catctaaacc actaggattg gtgtgggcaa taatttctgc cttgttgact
    26101 aaaatttcca acaaatcatc cgagaggggt tcttgacaat aagaaaaaac ggctctaata
    26161 gctgcaatag aaacggctgc cgaagacccc ataccacgct tttgtggcac ttgtgaaaca
    26221 atctcataag caattggttc ttgtagtcgc tgcaaataat ccaaggcagc ataaatggct
    26281 gttgatagag tatcataaaa atcaaagacc aatggcttat cagctggaaa aatatgacaa
    26341 accacctcaa tatctgttaa aggcaaagca atagctgggt agccatacac aacagcatgc
    26401 tcacctatca aaatgatctt actgtgtgcc ttaccatatc caatgttttc gttcattttt
    26461 tatcttttca ttactaattc ttctaaactt ttaccttact attttacact aaatgattag
    26521 aaaatgcgat gatatatctt tttaaaatca tttcttcact gaaattaaca ataaagacta
    26581 tctactcttt ttaggatcat aacaaaaatt ttcttatttc aaactacctt ctttaatcac
    26641 tcttctacta aattaaacgt taaaaaccag cctcatgggc tggttaagca tcgtttatta
    26701 cctttaccta gacattatta ctagctaaag gtactaaaaa atgtttaagt caaatcacca
    26761 ctgtaaaaac aatagcatcg tttttataat ttacagttat cgttccttta aataacttaa
    26821 ccatactttc tgccatagat aaaccaattc cataaccttt ttctttgcta ttatgggatt
    26881 cgtcttcgcg ataaaagcgt tcaaaaaagc ggctgtaatc aatggatttt ccttccaaat
    26941 aggtattaga aacttctaat ttcgctcgtt ttcgtcttct tccaatagtg gttaaagata
    27001 ccttgaccaa gcctttagga tcacaatatt tattggcatt atcaactaaa attgtcacaa
    27061 gttcaaacaa tgacttttcc tccgctttaa tcataatatt cggctgaatc gtcaaatcaa
    27121 aacgtttacc atctttcaaa accagactct taaaatcttc agctgcatct tgagcaatag
    27181 ctgaaaagtc taccatatgt aataccacat ctggctgttc ctccaaacga gccaaagtaa
    27241 tcatttgatt aatcaagcct gtcaatcgct tcacctgatc acttgtactc ttggtccatt
    27301 ctgattctcc agtcattaat tcgaccaatt cattattggc tgagataatg gctagtggtg
    27361 tttttaactc gtggcctgca ttagtaataa agcggcgctg cttctcataa ttttggacaa
    27421 aaggtttgat gaccataccg gaaaaaagac tcactaaaac aacaaaaaag ataaatcctc
    27481 caaaggccaa catcattgaa acagctaata aatctcctac actacgaaaa taaaaggtag
    27541 tatctaaaat aacaaccagt ttttcttcat ttggcagctg agtaatcaag tacgaataaa
    27601 cactatcttg gtgacggtaa ctgccttttt cttccccaga cttagcaaaa agtctagcaa
    27661 aatattgggc ttcttctcta tctaaagctg aaatattagc agtattagaa gaaagtagat
    27721 gtccattagc attaaaaatg acactataat accgaaactg gcttaggcta tcttcagaca
    27781 gtttcgttcc aagtcgttta gaactttccg tagtgccagg taatttacct ttatttgagg
    27841 aaattaaatg taaaatacgg ttaatttctt gttgactttg gtaacagcgt gccgtgttaa
    27901 taataccaac aattgaactt aaaataataa aaatggcaat agaagcaatc atgataaaac
    27961 gaatacggat acgattaaac atgtcacctc ctatttttct aataaacaat agctagtatc
    28021 tttatcacct gcaataatga catttgcttg aatagctaat aatttttgac gaagataaga
    28081 aatataaacc caaacaatag aagtatcata atcttcttgg tctgaccaaa catgttggta
    28141 aagcgtttta gtatccaagt actttccttg atttaacatt aaaaaggcca ttaatttacc
    28201 ttctttagaa gctaatcgta tagcattacc ggcactcaat tcttgctcat taatatttaa
    28261 tgtgacacca gcaaattgta atacctgagg agtaaaactt tctactcgtc tttccatcga
    28321 ccttaatcta gctaaaagtt cttttaatga gaaaggttta gtcagataat catcagctcc
    28381 cgcatctagt ccggtaacac ggtcattaat ttctgccata gccgtcagca taataatatg
    28441 tgagcaattt cctgaagcgc gaatctcctt taaagcctca atgccagact taatcggcat
    28501 catgatatct aaaatcataa tatcatatgc attgtctttg gctttatcaa ttgcctcttg
    28561 accgttaaaa accacatcaa cgtcataacc ttgatgagtc atggcagttg tcaaaacatt
    28621 agacatttgc cattcgtctt cagctaacaa aattttcata gttactcttc ccccgtcgtt
    28681 tcttgaatca attgacgaat ggtttgcatg gtaacatcac aagatgccaa ctcgtctgca
    28741 caacgcttta actctcttgt aatcatttct gcattagcaa cttgatgttt gtacttcatt
    28801 tgatgttcca agctagccca agagtcttga gcaatggttc gcaactgcac ttctataaaa
    28861 taacatcctt ttttttcccc taaaatatct ggaaaatgtg tttctaattc caaaatgaga
    28921 tgatatgatc tatagccatt aggcttggca tttaaaatat aatctttttc agtgttaact
    28981 gacataccag gaatgctttt gagcaagtct accatccgat aaatatcatc aataaaacca
    29041 caaataatgc gaataccgat actatcttta atgattttta acgcagattt gcttgttaga
    29101 ggaagctgtt tgcgttgaca tttttcaatc atcgaagctt ccgatttaat acgggatgta
    29161 aagtgttcgt atagtttaaa ccctgtttct tttttgcttt tgatattctc agcaataatc
    29221 acatctgtta ttgtctgtag taccaacggc aagtacactt caaatccgct atatatagag
    29281 ctggtagaat aatgttctag tctttctttc atacgcttat tataacaaat tttctcaaca
    29341 aatgcttaaa tctctgcaat gatcggttat ctttatttct aactatataa ctgcaaatga
    29401 tctatatcgt ttgtttttaa agcgctttta tatatttttt atacgttatt ttttaaaaat
    29461 accattgaat tacaaacaaa atcatagtaa acttgatcta taacgattac gttaacttat
    29521 taggagattt tatgaaaaaa tattttattt taaaaagtag tgtattgagt atcctgacta
    29581 gttttactct attagttaca gacgttcaag cagatcaagt tgatgtgcaa ttccttggcg
    29641 tcaatgattt tcacggcgct cttgataata ccggaacagc ttacacacca agtggtaaaa
    29701 taccaaatgc tgggacggct gctcaattag gtgcttatat ggatgacgct gagatagatt
    29761 tcaagcaagc aaatcaagac ggaacaagta tacgtgttca agctggagat atggtcggag
    29821 ccagtcctgc taactctgca cttttacaag atgagcctac tgtgaaagtc tttaacaaaa
    29881 tgaaatttga atatggcact cttggtaatc atgaatttga cgaaggacta gatgaattta
    29941 accgtatcat gacaggtcaa gcgcctgatc ctgaatcaac aattaatgat atcaccaaac
    30001 aatatgagca cgaagcttcg catcaaacca tcgtcattgc taatgtcatt gataaaaaaa
    30061 ccaatgatat cccctatggt tggaaacctt atgctataaa agacatagcc attaatgaca
    30121 aaatcgttaa gattggcttc attggtgttg tgactacaga gattccaaat ctcgttttaa
    30181 agcaaaacta tgaacactat caatttttag atgtagctga aaccattgcc aaatatgcta
    30241 aagaactgca agaacaacat gttcatgcta ttgtggtttt agctcatatt cctgcaacaa
    30301 gtaaagatgg tgttgttgat catgaaatgg ctacggttat ggaaaaagtg aaccaaatct
    30361 atcccgaaca tagtattgat attatttttg caggacataa tcatcaatac actaatggaa
    30421 ctatcggtaa aacacgtatc gttcaagccc tctctcaagg aaaagcttat gcagatgtcc
    30481 gtggtacgct agatactgat accaatgatt ttattaaaac tccatcagca aatgttgttg
    30541 ctgtagcacc aggtatcaaa acagaaaatt cagatatcaa agctataata aatcatgcta
    30601 atgatattgt taaaacagtt actgaacgaa aaatcggaac tgcaactaat tcttcaacta
    30661 tttctaaaac agaaaatatt gataaagaat cccctgtcgg taacttagta acaacggctc
    30721 agcttactat tgctaagaaa acttttccaa ctgttgactt tgctatgacc aataatggtg
    30781 gtattcgaag tgacctagtt gtcaaaaatg accggaccat cacctgggga gctgcacagg
    30841 ctgtacaacc atttggtaat atccttcaag tcattcaaat gactggtcaa cacatttacg
    30901 atgtcctaaa tcagcaatac gatgaaaacc agacctattt tcttcaaatg tcaggtttaa
    30961 catacactta tatagataat gatcctaaga actctgatac ccccttcaag atagttaagg
    31021 tttataaaga caatggtgaa gaaattaact taacaactac ttacaccgtt gttgtcaacg
    31081 actttcttta tggtggtggt gatggctttt cagcatttaa aaaagctaaa ttaatcggag
    31141 ctattaacac agatactgaa gctttcatca catatatcac aaatttagaa gcatcaggta
    31201 aaactgttaa tgctactata aaaggggtta aaaattatgt aacttcaaac cttgaaagct
    31261 cgacaaaagt taatagtgct ggtaaacaca gtatcattag taaggttttt agaaatcgtg
    31321 atggcaatat agtgtctagt gaaatcattt cagacctttt gacttctact gaaaacacta
    31381 ataacagcct tggcaaaaaa gaaacaacaa caaacaaaaa tactatctct agttccactc
    31441 ttccaataac aggggacaat tataaaatgt ctcctattat gacaatcctt gccttgataa
    31501 gcttaggtgg actaaacgct tttattaaaa aaaggaaatc ctagcgttta ctagtaatcg
    31561 atcaccctta tataatcagg catctttgcc aaaaaaccta aagcgtccta ctctaggttt
    31621 tttgttaaat taaaatacct tctagatgat ctaattcgtg ctggcatatt tgagcagtta
    31681 agcctgttaa gcttaatcgc tttggtcgcc aattatggtc caaatactca acagtaatct
    31741 tatcataccg ctgtgttttg cgatagccag ataacgacaa acaagattct ttagtttggt
    31801 aaattccctt tttagaaacc atcacaggat taaacataac caaatcaata aatcccatac
    31861 tcacaataac aatgcgtttt tgttcaccaa tcatattggc agccatccca agacattcct
    31921 gtctataaaa ggctaaggta tcttgtaaat cttggccaat ccatagatct tctttcttgg
    31981 cgacttgcgc tttttgctgt aataaaaaat gatctgttat gatttctcta atcattctta
    32041 tctccttaaa ccttcttttt aattcataaa ctacatgttc aatggactat tatcaccata
    32101 ggatagactt agtatcatct gtttaaaaca tcaggtgatt ccttatttca agataccttg
    32161 ggcaacttta tgaaattctg caatatgagt accaaataaa aattgacctg catcagcaga
    32221 ttgttgctaa gttctcatca caatattatc gaatttactg tctgcttctt caaatgtcta
    32281 agagagatag ttattgcttt gtgagatttt caaaccagat actgctttct cttgcatttg
    32341 cagccttaac aggtccaaac aaaacacctg ctgtttgaaa tgctttaata actgatatat
    32401 tgttaatagt tagtattata aattttctga atatttctgt caagtttttc agttgactta
    32461 acttttttac ttgatttttc ctcacgtaat aatagaaaag aagcgccata atgtaaacta
    32521 caccccaaac gttagataaa aaatctaacg tttggggtgt ttttgcatga cattaagcta
    32581 tgaagataag ctagatattt agtgctaaaa aaaccgaggg aactccgttt gaaagaagca
    32641 tctctgaaaa aaaaccatta caaagaatgg acaaagacga gttctgatta gattttcttt
    32701 taagaacggc taaattgact cgttctacct actattatca tcgattattg caacaataaa
    32761 cgtatcaaaa taaaacgaaa aggacttagt cctctacaac acagaactaa atcctttact
    32821 tcaaatagag tagccaactt ttggggctca gtgcaagagc acttcttttc tattatcact
    32881 tgtttattat aaacataaca ttaccatagt atacttatat gtctagtcca ctcaaatact
    32941 caaaccgttc atacgccaat aataaatcat tattgcgctg atcgagttcc ttttgtaatt
    33001 gagctaactg gccataatca ctaactacag ttaacatttg gttttcaatt tcttcaatat
    33061 tagcctcaat agttgctatt ttatcttcta tctgagccca ttcttgtttt tcaaggtagg
    33121 acatgcgctt tttctcctct ttcggaggaa gtggcacttc ttcagtgact attgctttag
    33181 ctaagtcagc ctcaactgtt tctttttcaa aagctttttc atcaaggtaa tcactgtaat
    33241 tcccataaaa aacacgaata tcgccttctt caaaggctaa aatcttagtg gctactttgt
    33301 ctaggaaata acgatcgtga ctaaccgtaa tgactggtcc tgcaaagtta gctaaaaagt
    33361 tttctaagac cgtcaaggtg gcaatgtcta aatcatttgt tggctcatca aggagaagaa
    33421 catttggctt ttcaatgagc agttttagca agtagagccg ttttttctcc ccaccagata
    33481 atttagcaat cagcgtgcca tgacttgatc tcggaaaaag aaattgttct aaaagctcac
    33541 tgatactcgt tgttcccacg cttgttttaa cctcatcagc cacttcttga aggtaattaa
    33601 tgacccgttt ggtctcatcc atatctttga gctgctgaga gaaataacct acacgaatag
    33661 tatctccaat atcaagcttc ccagaagttg gtttgagatc accgttgatg atatttaaca
    33721 gggtagattt tccgacgccg ttatctccaa caattccaat acgatcttta ttttgaataa
    33781 tcaaattaaa atccttaatc aactgtcggt cgccataagc aaaagaaagg tcttcaaagt
    33841 gaatcacctt cttcccaatt cggctcgttt cgaaagccat ctccaactta tccgcagaac
    33901 tgtcttggtg aacttctttt ttcaagtcag tgaaacgatt gattctagcc tgctgtttgg
    33961 ttgcacgcgc ctgtggctgc gtcctcatcc aggctaattc ttgtttatag agttgcttct
    34021 tcttgtgtaa attagcagca tctcgttcgt cttgttctgc ttttaagcgc acatagtctt
    34081 ggtaattgcc ttgatattct gtcagtcccg ctttatccaa ttcaaaaata cgggtagcca
    34141 catgatcaag gaaataacgg tcatgggtaa taaaaaggac ggttttttta gctgtcttga
    34201 gataggttgt taaccaagcg atggtgtcaa tatcgagatg gttggtcggc tcatccaaca
    34261 agagtaagtc agcagctcct agcaatactt gagctaactg gacacgtctt ctcataccac
    34321 ctgataggtc tcccactttt tgttccaaat ccgtgatgcc taattttgat aggactgttt
    34381 tgacatcact ttcaatagac caagcatcta agcgatccat ttcagacatg agggactcta
    34441 aggtctcttg tttatcttca gtataattcg ccatcaatag ttcatactga cgaatcagct
    34501 gaatcgcctt aacatcagat gacaataccg tatctaaaac agaggatgca tcgttaaatt
    34561 caggatcttg tgttaagtaa gcgattttgt aatcattggc tttagaaaat ggtgaatggt
    34621 ctccgtcaaa accaagcctt cccgacaaga catctaaaag agttgttttt cctgttccat
    34681 taaccccaat aatcccaata cggtcaaagt catgaataat aaaggaaata tcctgaaaga
    34741 ctgttttatc tcccaccgtt tttgtcaatt tctccaccaa aaaatggctc atgttgctaa
    34801 ttcctctcta acaaatgctt caattgtagt gaaatcatta tctaggcgtc cctctacaat
    34861 cgctaattca actttctcaa gcataagccc tagctgagga cctggtttca tcccaaaatc
    34921 cttaatcagg tgagaaccat taaggacgat atcgtatttg ttatgaatgg ctagcgcttg
    34981 atctaaagct tcaatgtggt ccatgtcaac agataagctt tgagcttttc ggaggccttc
    35041 cactagactt gccatttcct tgccgtactg gtaaatatcc aatttttcaa aagatctttc
    35101 ctgacgaatt ctataaagag caatcaactt tgtgacataa cgctgaaaat catttgaagt
    35161 cttccatgct tttaggaagc ttttaggatc ctcaatggct aaactaatca tcacataagc
    35221 ccaagcttgg tgatgatcac taaaggtaaa gttatctttc aaagaaacta tcagatgatt
    35281 taagcctgct tcctgctgct tcaagcctgg taaatagtca taagcctggc aagcaatcat
    35341 ggcagaaatc ccttttcgcc agtgcggtgc cgtcaataat ttatcaaatt cagtaaaaga
    35401 acgttccaca gaaatttttt ccaatagaga tgaatggctc ctcatagctt caaaagttgc
    35461 agcttcaatg tcaaaatcca gactcgccgc aaatcgaaag cctctcataa tgcgtagtgc
    35521 atcttcttca aaacgttcct ctgctttacc cactgctcgt aaccgttttt gctttaaatc
    35581 aatgagtcct ctaaatttat caataactcg accattttca tccaaggcca aggcattgac
    35641 ggtaaagtct cttcgtttta agtcttcctc taaagagcgc acaaaagaaa cctgactagg
    35701 acggcgataa tcaacataga catcttctgt cctaaaggtt gtgatttcat actcaccgcc
    35761 attttcaagc acgagcactg taccatgttc aatgccaaca tcgacagttc tgttaaaaat
    35821 cgctttagtc tcttcaggat aggaactagt tgcaatatct acatcatgaa taggacgctc
    35881 gagtaaaaca tctctgacgc ttcctcccac aaaataggct tcataaccag cttcttttat
    35941 tttagtcaat atgggtaaag ccttctgaaa ctcagaaggc attgtcatta atttcatacg
    36001 ttgttttcta acctatcatc caactagccc aatctaaagt gtgattaggc tacttgggtt
    36061 ctatcacatt ttgttattgt tttagtgatt cttgcaatta actatttttt ctaatcgaca
    36121 attaaagcct cggtgttacg ccaaatgcaa tggctccttc tcctaaatgg gtagcaatca
    36181 ccgctccaaa atgaacctct tcaatgtcat attgataacc actgtcttgt aagagtcgtt
    36241 tcaaataatc agctttgtct tgtgcttttg agtgaataat agacacatta tactgaccgt
    36301 ctgctatcaa gtcatttaaa atctcaacca agcgtttcat ggctttcttt tctgttctca
    36361 ctttttcata aacaacgatt tttccctctt catcaaagcg taaaataggt ttaatactca
    36421 aaagatttcc aagaagagca gacccatttg acaggcgtcc gcctttaacc agatgattaa
    36481 ggtcatcaac cataataaag gctgtcgtcc catcaatctg ttcttgcagc ttgtttaaaa
    36541 tagcttgaaa tgtcattcct tgacgtgacc aatctagcac attttttacc atactaccta
    36601 aaggagcaga tgtgatctta ctgtctggaa atgccatttc aatctcagga tgttcttcag
    36661 ctaaaaattg aatattttgc caaaagcctg agattcctcc agctaagaac aagccaataa
    36721 catgtgtata acccttagaa gacaaaagtc ctaaaagatt atctagttca gataaacttg
    36781 gctgacttgt cttgggaaga ttttgggagt cagccatctt ttgataaaaa tcatctatac
    36841 tcaaatttcg accttcaaaa taggtctcat cgtcaatgat aactggtata tcaaggctaa
    36901 aaatagcttt atcttgtttc agatctgttg gtagtgttgc tgtactgtca gtaattactg
    36961 ctaatttcat taatttttaa actccaaatg aatacctgga cgatccaagg caatttctgt
    37021 gacttcataa gtcaatcgct taaccatgtc tagcaaagga gcagctaatg attcaacttc
    37081 ctcttgcgta aattcgcttg gtttatccac taaacgatct aaaatacgaa ccatttgtga
    37141 gatgacccca ctaataacaa attcttcttt gacaataaca aattgcaata cagatacaat
    37201 tactgtttct ttttgctgct catctttatc aatcaactga aaagtcactt caaaattggt
    37261 ctctggtgtt ccgttttctt tttcccactc taaatttcta gcatcataat ggtactggtt
    37321 gacaaattct ttttcacgaa ctaattgcat tttttattct ccttggtatc aatatgatcc
    37381 attatagcat agatttgaaa attattaaag tagcccctaa actactattt ttgcataacg
    37441 ttttaaacag tgctatctct cgaacagata tctatttttt cacctattta tatttagtcg
    37501 tccttatact gacattatat caaaaaaaca cccgttagtg gtcttgtact gcacctcaat
    37561 taaaacagaa ccactggtca ggtaagtttt aagtccagga taaaaaggtt tatcaccaag
    37621 gcctcatcat gcttagccaa gtatttcgaa ctagcttgtc ttagctctag tcgctcaaac
    37681 gtaaatccta ggcgttcaat ccgccgcaaa acctctccaa ctaacccata cttaaaccca
    37741 tagggcttaa tcatcgctcc gcccttcttc ttttatccat tataaaataa aaatgtttta
    37801 acagacaaaa aataggaaag taccagacta ttggatttat ttttttatct caaactccat
    37861 taacgatgtt gagttaaagg cattcaaaac aacatagatc gtaagctaac aagatttttt
    37921 atcaattgaa cctatcgtcc ccagttatat cacgacctct tctggatgag gtcttttttt
    37981 atttgtctaa tttcatcaac gcttcttccc ctctttcttc tatcacagct ctcctattgc
    38041 tcacttcctc atgcagcaac tatatcatca aaaaaccgtc catttttaag cacaaccact
    38101 actgtatctc ttgtgatatc tccattgtca atcgcttgtt taattttatt aaaaattatt
    38161 ttaaaaaata aatattattt taaaaacttg caataatata tgtctatatt atataatttc
    38221 tttatcataa aattatatag aaaaaggtat tcttatgaga aaaagatgct attcaacttc
    38281 agctgcagta ttggcagcag tgactttatt tgctctatcg gtagatcgtg gtgttatagc
    38341 agatagtttt tctgctaatc aagagattag atattcggaa gtaacacctt atcacgttac
    38401 ttccgtttgg accaaaggag ttactcctcc agcaaaattc actcaaggcg aagatgtttt
    38461 tcacgctcct tatgttgcta accaaggatg gtatgatatt accaaaacat tcaatggaaa
    38521 agacgatctt ctttgcgggg ctgccacagc agggaatatg cttcactggt ggttcgatca
    38581 aaacaaagaa aaaattgaag catatctaaa aaaacaccca gataaacaaa aaatcatgtt
    38641 tggtgatcaa gaattattgg atgtaagaaa agttattaat accaaaggtg accaaacaaa
    38701 tagcgagctt tttaattatt tccgagataa agctttcccc ggtttgtcag cacgccgaat
    38761 tggagttatg cctgatcttg ttttagatat gtttatcaat ggttattact taaatgttta
    38821 taagacacag actactgatg tcaatagaac ctatcaagag aaagatcgcc gaggtggtat
    38881 ttttgacgcc gtatttacaa gaggtgatca aagtaagcta ttgacaagtc gtcatgattt
    38941 taaagaaaaa aatctcaaag aaatcagtga tctcattaag aaagagttaa ccgaaggcaa
    39001 ggctctaggc ctatcacaca cctacgctaa cgtacgcatc aaccatgtta taaacctgtg
    39061 gggagctgac tttgattcta acgggaacct taaagctatt tatgtaacag actctgatag
    39121 taatgcatct attggtatga agaaatactt tgttggtgtt aattccgctg gaaaagtagc
    39181 tatttctgct aaagaaataa aagaagataa tattggtgct caagtactag ggttatttac
    39241 actttcaaca gggcaagata gttggaatca gaccaattaa agcgtatcaa taagaaagaa
    39301 taccttcaac agatgatggt attctaagga ctaatactat tgcagggaat ttttttatag
    39361 atgggcaaca gcaaaaaaca ttaataaatc ctataaaaat cgataaggat attgttacga
    39421 ttcaagagtt cgattttaaa ataagaaaat ttttgatgga atcaaaagaa attcatttaa
    39481 ctaagtctcc ttatataagg gggagtttag aaattcacag taaaaatagg aaacatgaaa
    39541 aaatcaattt atatgacgca aaacccaata gcaccagatc tgatgtcttt aaaaaatata
    39601 aagacaataa gactataaac atgaaagatt tcagccattt tgatatttat ctttggacta
    39661 aataagctaa aagctttgga taaatatgat caattgacct ataataacat tgataccaaa
    39721 tctaaaactg ctcagattga attgcgcccc aaaagttaga caaaaaatct aataattggg
    39781 gtgtttttgt ctggcattaa gtttagctaa taaccttgct taaatcacat taaaccaata
    39841 atggaaaaag acatctccaa ataaatgcta tgatggaact atatgataga gtgatcaagg
    39901 ttggcaatat caacacaact attatcatca tttcctaaac tctaaaggaa ttcgtccgtc
    39961 tatgtcacgt aaaagaaaca gtcctgacaa tggcatgatg gaatctttct ttggcatctt
    40021 aaagtcagaa atgttctatg gttatgagaa taactataaa tcactagaag acttagaaca
    40081 agcgattaca aatgacattg attattacaa cgataaacat atcaaagtaa aactaaaagg
    40141 atttagttct gtacaataca gaactaaatc ctttacttaa aatagagtat ccagcttttt
    40201 tggggtcagt gaaagcagat tgttgttagt gttacattaa taagtcatgc gtttagccca
    40261 agcctcatca actgctaggg tctccgcatc agtgtaatta cgacgatact cattccaaac
    40321 ataacccgaa gttgctagac cagtttcttg agctgagcta ttagcaacat cataagccgt
    40381 caaaccatag gttgcaataa tattatttag ttttaagtta taactggtgt ctgtagcgta
    40441 taagccagtt agagctgctg tagcatcttg atacgatagc gtgtttgatt ttctagcacc
    40501 tatataagtg ctagaactta gcaagtctgc atagtcatta agggagtctg caatacttgg
    40561 ataagctcta aaggcttgat caatcgtata ggtattgcca ttaccatcat cttcccaagt
    40621 tgacatggta actgacgaac cattataggc ccctttgatg ccaaagaagt tatgataggg
    40681 ggcttgactt agacttgatt taccattact tgattctaaa atcgcttgtg ctatcataac
    40741 agacgcataa agatcacgtt cttgaccaat agtactagca gttggaccaa tttcatcaat
    40801 aaaatgtcgg gttgaagaac tggcgatagt ttcagctgac acgtttgaag ttttatgaga
    40861 ttgtctcatt gcactataag ctcctaaaca agctgctaga acaaaaagac tgataagtac
    40921 aagcttacct ttcttttttg tcattattca catatccttt tttattcatt ttctatgttt
    40981 ctattatagc acacgaacgt ttaaattaac ttttccacag ataatttaat gagattgata
    41041 acttttgtct tgaaatcgac atatttcttc tgattttttt aaaattgtgg ataactattt
    41101 catcagacca tcaaaattag tgagttgata ccattcaatc aattcattta atttggtatg
    41161 gtaagttgta tcagtg
//
