LOCUS       NZ_CP035434            20873 bp    DNA     circular CON 24-JUL-2024
DEFINITION  Streptococcus pyogenes strain emm75.1 chromosome, complete genome.
ACCESSION   NZ_CP035434
VERSION     NZ_CP035434.1
KEYWORDS    RefSeq.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1887700)
  AUTHORS   Davies,M.R., McIntyre,L., Mutreja,A., Lacey,J.A., Lees,J.A.,
            Towers,R.J., Duchene,S., Smeesters,P.R., Frost,H.R., Price,D.J.,
            Holden,M.T.G., David,S., Giffard,P.M., Worthing,K.A., Seale,A.C.,
            Berkley,J.A., Harris,S.R., Rivera-Hernandez,T., Berking,O.,
            Cork,A.J., Torres,R.S.L.A., Lithgow,T., Strugnell,R.A., Bergmann,R.,
            Nitsche-Schmitz,P., Chhatwal,G.S., Bentley,S.D., Fraser,J.D.,
            Moreland,N.J., Carapetis,J.R., Steer,A.C., Parkhill,J., Saul,A.,
            Williamson,D.A., Currie,B.J., Tong,S.Y., Dougan,G. and Walker,M.J.
  TITLE     Atlas of group A streptococcal vaccine candidates compiled using
            large scale comparative genomics
  JOURNAL   Nat. Genet. (2019) In press
REFERENCE   2  (bases 1 to 1887700)
  AUTHORS   Davies,M.R., McIntyre,L., Mutreja,A., Lacey,J.A., Lees,J.A.,
            Towers,R.J., Duchene,S., Smeesters,P.R., Frost,H.R., Price,D.J.,
            Holden,M.T.G., David,S., Giffard,P.M., Worthing,K.A., Seale,A.C.,
            Berkley,J.A., Harris,S.R., Rivera-Hernandez,T., Berking,O.,
            Cork,A.J., Torres,R.S.L.A., Lithgow,T., Strugnell,R.A., Bergmann,R.,
            Nitsche-Schmitz,P., Chhatwal,G.S., Bentley,S.D., Fraser,J.D.,
            Moreland,N.J., Carapetis,J.R., Steer,A.C., Parkhill,J., Saul,A.,
            Williamson,D.A., Currie,B.J., Tong,S.Y., Dougan,G. and Walker,M.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2019) Department of Microbiology and Immunology,
            University of Melbourne, The Doherty Institute of Infection and
            Immunology, Melbourne, Victoria 3000, Australia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 80x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_005163865.1-RS_2024_07_24
            Annotation Date                   :: 07/24/2024 01:48:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,868
            CDSs (total)                      :: 1,779
            Genes (coding)                    :: 1,714
            CDSs (with protein)               :: 1,714
            Genes (RNA)                       :: 89
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 36 of 65
            Pseudo Genes (incomplete)         :: 31 of 65
            Pseudo Genes (internal stop)      :: 25 of 65
            Pseudo Genes (multiple problems)  :: 24 of 65
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:28:47
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 671044
            Orig. end                         :: 691917
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP035434.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20873
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20873
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20873
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10873](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10873
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    complement(765..785)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 25.95"
                     /tool="antismash"
     misc_feature    1659..1672
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 21.93"
                     /tool="antismash"
     gene            2046..2276
                     /locus_tag="ETT65_RS03635"
                     /old_locus_tag="ETT65_03635"
     CDS             2046..2276
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003105222.1"
                     /locus_tag="ETT65_RS03635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_03635"
                     /product="YkuJ family protein"
                     /protein_id="WP_002983885.1"
                     /transl_table=11
                     /translation="MESHLVRIINRLELMVTDGGNLKRNFERDGVVVAEVAFSNDPENG
                     PVFTLRDVEARESYSFDSIDLIAMEIYDLLY"
     gene            2403..3089
                     /locus_tag="ETT65_RS03640"
                     /old_locus_tag="ETT65_03640"
     CDS             2403..3089
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018000.1"
                     /locus_tag="ETT65_RS03640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_03640"
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_023610107.1"
                     /transl_table=11
                     /translation="MDLSFLPKYWAYFNYGVLVTIMISVSVVFFGTLIGVLVTLIKRSH
                     VKPLTWVVNLYVWIFRGTPMVVQIMIAFAWMHFNNMPTIGFGVLDLDFSRLLPGIIIIS
                     LNSGAYISEIVRAGIEAVPKGQLEAAYSLGIRPQNAMRYVILPQAFKNILPALGNEFIT
                     IIKDSALLQTIGVMELWNGAQSVVTATYSPISPLLVAAFYYLMVTTVMAQLLAVLECHM
                     AQGGNH"
     gene            3089..3823
                     /locus_tag="ETT65_RS03645"
                     /old_locus_tag="ETT65_03645"
     CDS             3089..3823
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407690.1"
                     /locus_tag="ETT65_RS03645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_03645"
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="WP_002989107.1"
                     /transl_table=11
                     /translation="MTEAIISIKDLHKYYGHNEVLKGIDLDIMPGEVVVIIGPSGSGKS
                     TLLRTMNLLEVPTKGQIRFEGIDITDKKNDIFSMREKMGMVFQQFNLFPNMTILENITL
                     SPIKTKGMAKAEADKTALSLLDKVGLSEKAKAYPASLSGGQQQRIAIARGLAMDPDVLL
                     FDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAKEVADRVIFMDGGVIVEEG
                     SPNQLFDLTKEERTKDFLSRVL"
     gene            3972..5381
                     /locus_tag="ETT65_RS03650"
                     /old_locus_tag="ETT65_03650"
     CDS             3972..5381
                     /EC_number="4.1.99.3"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003904 - deoxyribodipyrimidine
                     photo-lyase activity [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989109.1"
                     /locus_tag="ETT65_RS03650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_03650"
                     /product="deoxyribodipyrimidine photo-lyase"
                     /protein_id="WP_002993337.1"
                     /transl_table=11
                     /translation="MVSVMWFRRDLRIDDQKALAHAIASQSPTLCVFQFNKEQLNLLHS
                     RNQSSFITSVLAFRKLLKCEGIDLYLMYGDLMTCFEQLLTQLKDWTDVYFNYDESGYGR
                     LRDQKAAQFFKKNGIAVHTYQDHYLHGSQEIINQSGQPYKVFTPYYRIWQNYPKETPIK
                     VELSQGRWLNLETPDDVLRTVESFKDEKYQDVATFDEASKQLNRFIQDQLAAYHANRDF
                     PAQLGTSRLSPFLRIGAIGIRTVYHAVRQAPNSLGQATFLKELAWRDFYNMVYVAYPDQ
                     KTQPIQKAFSQIEWVNNPDWFQLWKEGKTGYPIVDAAMLQLQKTGWMHNRLRMIVASFL
                     TKDLLCDWRLGEQYFQQQLIDYDAASNIGGWQWAASTGTDAVPYFRIFNPVTQGKRFDP
                     KGEFIKAYLPQLEHVPEKYLHEPWKMPKYLQESVSCIIGTDYPQPIVDHAKQREQAIAK
                     YEWAKEKAKIE"
     misc_feature    complement(5497..5508)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.16"
                     /tool="antismash"
     misc_feature    5526..5541
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 22.0"
                     /tool="antismash"
     gene            5559..7253
                     /locus_tag="ETT65_RS03655"
                     /old_locus_tag="ETT65_03655"
     CDS             5559..7253
                     /EC_number="5.4.2.-"
                     /GO_function="GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635581.1"
                     /locus_tag="ETT65_RS03655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_03655"
                     /product="phospho-sugar mutase"
                     /protein_id="WP_002993334.1"
                     /transl_table=11
                     /translation="MTYNEVYQEWLHNNDLSDDIKADLAAIKDNEAEIQDRFYKTLEFG
                     TAGLRGKLGAGTNRMNTYMVGKAAQALANTIIDHGPEAVKKGIAVSYDVRYQSRTFAEL
                     TCSIMAANGIKAYLYKGIRPTPMCSYAIRALGCISGVMITASHNPQAYNGYKAYWQEGS
                     QILDDIADQIAQHMAALTQYEEIKQMPFEKALDSGLVTYIDESIEEAYKKEVLGLTIND
                     TDIDKSVRVVYTPLNGVGNLPVREVLRRRGFENVYVVPEQEMPDPDFTTVGYPNPEVPK
                     TFAYSEKLGKAVDADILIATDPDCDRVALEVKNAVGDYVFLNGNKIGALLSYYIFSQRF
                     DLGNLPANPVLVKSIVTGDLSRAIASHYGIETVETLTGFKNICGKANEYDVTKQKNYLF
                     GYEESIGFCYGTFVRDKDAVSASMMIVEMAAYYKKKGQNLLDVLQTIYATFGYYNERQI
                     ALELEGIEGQKRIARIMEDFRQTPIASVAEMALDKTIDFIDGYQDFPKQNCLKFYLDDG
                     SWYALRPSGTEPKIKFYLYTIGQTQENSATKLDAIEAACRTKINQVN"
     gene            7461..8315
                     /locus_tag="ETT65_RS03660"
                     /old_locus_tag="ETT65_03660"
     CDS             7461..8315
                     /GO_function="GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922486.1"
                     /locus_tag="ETT65_RS03660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_03660"
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="WP_002989114.1"
                     /transl_table=11
                     /translation="MTELIDGKALAQKMQQELAAKVNNLKQKKGIVPGLAVILVGDDPA
                     SQVYVRNKERAALTVGFKSETVRLSEFICQEELIAVIERYNADNTIHGILVQLPLPNHI
                     NDKKIILAIDPKKDVDGFHPMNTGHLWSGRPLMVPCTPSGIMELLREYNVNLEGKHAVI
                     IGRSNIVGKPMAQLLLDKNATVTLTHSRTRQLEEVCRCADVLIVAIGQGHFITKQYIKE
                     GAIVIDVGMNRDDNGKLIGDVAFDEVAEVAAKITPVPGGVGPMTIAMLLEQTYQSALRS
                     THK"
     misc_feature    complement(8382..8398)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.76"
                     /tool="antismash"
     misc_feature    8391..8405
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.26"
                     /tool="antismash"
     gene            8468..9808
                     /gene="xseA"
                     /locus_tag="ETT65_RS03665"
                     /old_locus_tag="ETT65_03665"
     CDS             8468..9808
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="xseA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989115.1"
                     /locus_tag="ETT65_RS03665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_03665"
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="WP_002992349.1"
                     /transl_table=11
                     /translation="MADYLTVTHLTKYLKLKFDRDPYLERVYLTGQVSNFRKRPTHQYF
                     SLKDESAVIQATMWAGVYKKLGFDLEEGMKINVIGRVQLYEPSGSYSIVIEKAEPDGIG
                     ALALQFEQLKKKLTAEGYFEQKHKQPLPQFVSKIGVITSPSGAVIRDIITTVSRRFPGV
                     EILLFPTKVQGDGAAQEVVANIRRANQREDLDLLIVGRGGGSIEDLWAFNEEIVVQAIF
                     ESQLPVISSVGHETDTTLADFVADRRAATPTAAAELATPITKTDLMSWIVERQNRSYQA
                     CLRRIKQRQEWVDKLSQSVIFRQPERLYDAYLQKIDRLSMTLMNTMKDRLSSAKENKVQ
                     LDHALANSQLQTKIERYQDRVATAKRLLMANMASQYDSQLARFEKAQDALLSLDASRII
                     ARGYAMIEKNQALVASVSQITKGDQLTIKMRDGQLDVEVKDVKNENI"
     gene            9786..10001
                     /locus_tag="ETT65_RS03670"
                     /old_locus_tag="ETT65_03670"
     CDS             9786..10001
                     /EC_number="3.1.11.6"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983901.1"
                     /locus_tag="ETT65_RS03670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_03670"
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_002983901.1"
                     /transl_table=11
                     /translation="MSKTKTFEENLQDLETIVNKLENGDVPLEEAISEFQKGMLLSKEL
                     QKTLQAAEKTLVKVMQADGTEVDMDD"
     gene            10001..10873
                     /locus_tag="ETT65_RS03675"
                     /old_locus_tag="ETT65_03675"
     CDS             10001..10873
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888744.1"
                     /locus_tag="ETT65_RS03675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_03675"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_011054706.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4.8e-51, bitscore:
                     170.2, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKLARIDEAIRRYYKTTSNGVSEELIDAILYSVDSGGKRIRPLI
                     LLEMIEGFGVSLQNAHFDLAAALEMIHTGSLIHDDLPAMDNDDYRRGRLTNHKQFGEAT
                     AILAGDSLFLDPFGLIAQAELNSEVKVALIQELSLASGTFGMVGGQMLDMKGENQALSL
                     PQLSLIHLNKTGKLLTFPFKAAALVTDQAITVRQQLEQAGMLIGHAFQIRDDILDVTAS
                     FEDLGKTPKKDLFAEKATYPSLLGLEASYQLLTESLDQALTIFQTLENDVGFKPQIITK
                     LIEGLRLNA"
     gene            10866..11693
                     /locus_tag="ETT65_RS03680"
                     /old_locus_tag="ETT65_03680"
     CDS             10866..11693
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017216.1"
                     /locus_tag="ETT65_RS03680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_03680"
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="WP_136097957.1"
                     /transl_table=11
                     /translation="MPKERVDVLAYKQGLFETREQAKRGVMAGLVVSVINGQRYDKPGD
                     KIDDGTELKLKGEKLKYVSRGGLKLEKGLHVFGVSVANQIGIDIGASTGGFTDVMLQDG
                     AKLVYAVDVGTNQLVWKLRQDPRVRSMEQYNFRYAQPEDFSEGQPVFASIDVSFISLNL
                     ILPALHNVLSDQGQVIALIKPQFEAGREQIGKKGIVKDKQIHEKVIQKVMDFASGYGFT
                     VKGLDFSPIQGGHGNIEFLAHLVKSQTPETLAPHLIQEVVAKAHKEFEKHEKK"
     gene            11680..12150
                     /locus_tag="ETT65_RS03685"
                     /old_locus_tag="ETT65_03685"
     CDS             11680..12150
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983907.1"
                     /locus_tag="ETT65_RS03685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_03685"
                     /product="arginine repressor"
                     /protein_id="WP_002983907.1"
                     /transl_table=11
                     /translation="MKKSERLELIKKMVLTHPIETQHDLLRLLAEHGLELTQATISRDM
                     NEIGIVKIPSGSGRYIYGLSQDSGKKIVQGPRSIKSTILAVSDKTKGLEQHLYLKVVPG
                     NSKLIKRYLLADFSKAIFSLIADDDSLLLIAKSPSEADMIRQEILLWMQGIT"
     gene            12172..13833
                     /gene="recN"
                     /locus_tag="ETT65_RS03690"
                     /old_locus_tag="ETT65_03690"
     CDS             12172..13833
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051804.1"
                     /locus_tag="ETT65_RS03690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_03690"
                     /product="DNA repair protein RecN"
                     /protein_id="WP_030126970.1"
                     /transl_table=11
                     /translation="MLLEISIKNFAIIDEISLNFENGMTVLTGETGAGKSIIIDAMNMM
                     LGARASTEVIRRGANKAEIEGFFSVDATPELVACLESSGIAMEEELIIRRDIFANGRSV
                     SRINGQMVNLATLKQVGQFLVDIHGQHDQEELMRPQLHQQILDAFGDKAFEQLKENYQL
                     IFDRYKSLRRQVIDKQKNEKEHKDRIDMLAFQIAEIEAAALSRGEDDRLNQERDRLMNH
                     KQIADTLTNAYVMLDNDDFSSLSNIRSSMNDLLSIEQFDSEYKGMSTSISEAYYILEEV
                     SKQLSDTIDQLDFDGGRLQEIEFRLDTLNSLTRKYGGNVNDVLDYYDNIIKEYQLLTGD
                     DLSSGDLEAELKALEKQLVAAATNLSERRHQLAEQLEAEIKAELKELYMEKADFKVHFT
                     TSKFNRDGNESLEFYISTNPGEGFKPLVKVASGGELSRLMLAIKAAISRKEDKTSIVFD
                     EVDTGVSGRVAQAIAQKIYKIGRHGQVLAISHLPQVIAIADYQYFISKESKEESTVSKV
                     RLLTPEERVEEIASMIAGTDMTQAALTQARELLAKH"
     gene            14005..14964
                     /locus_tag="ETT65_RS03695"
                     /old_locus_tag="ETT65_03695"
     CDS             14005..14964
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285633.1"
                     /locus_tag="ETT65_RS03695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_03695"
                     /product="LPXTG cell wall anchor domain-containing protein"
                     /protein_id="WP_137002478.1"
                     /transl_table=11
                     /translation="MTSKKACLSSIIVLASLTCGNDTVSANHLSATGDKFDDCSTLVEK
                     DVAPKDELEMLAWSSSQTTDDADRDYEDFLDDDSFNDDSFNDDSFNDDSFISQNETDKM
                     FENLTDDRLLDELDEEDTIEPEQNVIMPSDDELFDLTDAVETRLTVSSAPHLEAELPKP
                     HLRSLSDTALRSGEIRGHLDNKLDALSVTATKLALTMAQKFDLTTHVYSIGESFSEVLA
                     AHYEDRKAESAFSKKKRFHLPIATPDVVIEELRRLVSSIGSSKEDVSVPYNRKLGMAVA
                     KRKIALPQTGEGFSYYPALLGLMILGLTPIMIPKKINN"
     gene            15192..16031
                     /locus_tag="ETT65_RS03700"
                     /old_locus_tag="ETT65_03700"
     CDS             15192..16031
                     /GO_function="GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264715.1"
                     /locus_tag="ETT65_RS03700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_03700"
                     /product="DegV family protein"
                     /protein_id="WP_002989125.1"
                     /transl_table=11
                     /translation="MGTIKIVTDSSITIEPELIKALDITVVPLSVMIDSKLYSDNDLKE
                     EGHFLSLMKASKSLPKTSQPPVGLFAETYENLVKKGVTDIVAIHLSPALSGTIEASRQG
                     AEIAEAPVTVLDSGFTDQAMKFQVVEAAKMAKAGASLNEILAAVQAIKSKTELYIGVST
                     LENLVKGGRIGRVTGVLSSLLNVKVVMALKNDELKTLVKGRGNKTFTKWLDSYLAKNSH
                     RPIAEIAISYAGEASLALTLKERIAAYYNHSISVLETGSIIQTHTGEGAFAVMVRYE"
     gene            16024..16866
                     /locus_tag="ETT65_RS03705"
                     /old_locus_tag="ETT65_03705"
     CDS             16024..16866
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635578.1"
                     /locus_tag="ETT65_RS03705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_03705"
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_168390493.1"
                     /transl_table=11
                     /translation="MNNRHLFSGIFFFVISLCLAFLLLNIIIPKSNSCLKKSDFLKKEQ
                     VAIQYVAIGDSLTEGVGDLTHQGGFVPLLTNDLSEYFKANVNHQNYGVSGDTSQQILDR
                     MIKQKQIQLSLKKADIMTLTVGGNDVMAVIRKNLADLQVSSFRKPARQYQKRLRQIIEL
                     ARKDNKDLPIFILGIYNPFYLNFPELTDMQKVIDDWNTKTKEVVGEYDRVYFVPINDLL
                     YKGINGQEGIVHSSGDQTTIVNDALFTGDHFHPNNTGYQIMSNAVMEKIKKHEKKIKP"
     gene            16844..17431
                     /locus_tag="ETT65_RS03710"
                     /old_locus_tag="ETT65_03710"
     CDS             16844..17431
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922482.1"
                     /locus_tag="ETT65_RS03710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_03710"
                     /product="YpmS family protein"
                     /protein_id="WP_002989129.1"
                     /transl_table=11
                     /translation="MKKKSNLNWWKWSFLCLLAFNTAFLMVIASRLIQVREPESELIAK
                     KPVKNIKIGTFVTTREQLNETVASYLKDYQTKKMSYKFYATSSSILFEGTYQLLGYEVP
                     LYIYFQPHRLENGAVQLQVISFSVGTLPLPEKDVLQYLKSSYKLPSFVKVMPNQSAIVV
                     NLQDIQNDAKVYLKAKKIDLFNDEISFNIYKK"
     gene            17530..17805
                     /locus_tag="ETT65_RS03715"
                     /old_locus_tag="ETT65_03715"
     CDS             17530..17805
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1132: DNA-binding
                     protein HU 1"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /locus_tag="ETT65_RS03715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_03715"
                     /product="HU family DNA-binding protein"
                     /protein_id="WP_002983920.1"
                     /transl_table=11
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVDAVFSTIEAFLAEGEKVQL
                     IGFGNFEVRERAARKGRNPQTGAEIEIAASKVPAFKAGKALKDAVK"
     misc_feature    18050..18068
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 23.56"
                     /tool="antismash"
     misc_feature    18086..18099
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     medium, score: 26.23"
                     /tool="antismash"
     misc_feature    complement(18144..18158)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 22.54"
                     /tool="antismash"
     gene            18149..20011
                     /locus_tag="ETT65_RS03720"
                     /old_locus_tag="ETT65_03720"
     CDS             18149..20011
                     /EC_number="7.2.2.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0015662 - P-type ion transporter activity
                     [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1037: heavy metal
                     translocating P-type ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528775.1"
                     /locus_tag="ETT65_RS03720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT65_03720"
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="WP_136075880.1"
                     /transl_table=11
                     /translation="MTIRQWMADHLHLMETLACLVLIIIGLAFLHSFPQVASAIFITAF
                     LIGGYASAKTGILDLVKNKHLSVDILMILAAIGAGIIGYWLEGALLIFIFSLSNTLEEM
                     AMEKSKDAISALMSLTPDTARQYQEDGHILEVETRSLSVGDRLQVRKGEAVPIDGQLLS
                     PFGQFDESMVTGEPITVDKAEGQDLIGGTINQGQTIDMLVTIENDDTLFAKIINLVESA
                     QEKKSKTATFIESLEDGYVKFVLVLIPAFILFSHFVLFWTWLAAFYRGMILLTVASPCA
                     LIASSTPASLAAISRAARKGLIIKGGDIVDNMGDIKAVVMDKTGTLTQGKPSVVNAHYL
                     EDELLVNRLVKGAETASTHPISKALLEYTEKLEPLTFDHLEEISGKGFQGFYQGQEWRI
                     GKKTFILEKVQDLSAFEETIQVEENQGKTLIFVSRDHQLIAYYALLDDIKIESKRAIKS
                     LHAMGIKTVMLTGDQERTANYVAQKLGIDEVVANCMPQDKVAKLAELKTKYGFVAMVGD
                     GINDAPALAQADVSYAIGSGTDIAMESADSVIMDDLTRIPFSIQLSRKMKTIIKQNIVF
                     ALSVITLLILANVFQVVNLPLGVVGHEGSTILVILNGLRLLSFK"
     misc_feature    20287..20302
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.81"
                     /tool="antismash"
     misc_feature    complement(20319..20333)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.55"
                     /tool="antismash"
ORIGIN
        1 agaacttgta agaacatgtg catgacgtca ggatgggctt tttccacctc atctaagaga
       61 ataagggaat aaggattgcg acgaacttgt tcggttagtt gtccagcttc ttcatagccg
      121 acataacctg gaggagcccc gactaatttg gcgacagcgt gtttttccat gtattcggac
      181 atgtcaaagc gaatcatatt gtttgtcgaa ccaaagagtt caatggctag ttgtttagac
      241 aattctgttt taccaacccc agtcggtcca acgaatagga aagaaccaat agggcgattt
      301 ggagttccta atcccacacg gttacgacga atagccttaa cgattttatc aacagcatcg
      361 tcttgcccga tcacgtgtgc tttcagatca ttggctaagt ttacgagttg agactgttcc
      421 ttttctttta agtccccaac tggaatatta gttttttgct ctacaatagc ttcaatggtt
      481 ttttcagtaa tgatgggaat atcttgctca tcgacttttt gagcctgcat ttctttgtat
      541 tttgtaattt gatcgcggaa ataagctgcg cgttcatagt cttcgtctcg agtagcttgc
      601 gccttgagat tctcagcttc aataagacgt ttgtcaattt ctttaggatc aacaaagttg
      661 agggttagat tcattttgga accagcttcg tccagaaggt caatagcctt atcaggaaga
      721 aaacggtctt gaatatagcg gttagataaa tgagcagcag cttcaatagc ggctgggcta
      781 tatttgacat gatgatagtc ttcgtatttc ggttggatac cttttaaaat cgtgatggtt
      841 tcctcaacag aaggttcatc aactttaacg ggttgcatac gtcgttctaa ggcagcgtct
      901 ttttcaataa tacggtattc atttaaggtg gtagcgccga ccaactgcaa ttcaccgcgg
      961 gccaaggctg gttttaaaat attaccagca tccatattgc cgtctcctgc agaaccagca
     1021 ccgacaatct catgaatttc atcaataaag agaatcacat ccttgcgatt gcgaatttct
     1081 tccattaatt tttgcatgcg ctcttcaaac tgaccacgga tacctgttcc ctgaacgagg
     1141 ctaaccacat caagacgaat cacttgcttg ccttggagtt tttgaggaac agtaccatca
     1201 ataatttttt gagccaaacc ttctacaaca gcagttttac caactccagg ctcaccaatt
     1261 agcacaggat tatttttagt acggcggttg aggatctcga taacgcgtgt aatctcttcg
     1321 tcacgaccaa taacaggatc aatattacca tttcttgcaa tatctgtgac attaatccca
     1381 aactcttcta acaagccctt tgcttgctga tttggtgttt gtggctgagc aggtcgttgt
     1441 ccgttgtagt taccaccata gcgtcctccg ccatttccat tttgccctgc ctgagtaggt
     1501 ggggtatttg gaagattacc aaaagctcta aaattattca aatcaccaaa aaagtcatca
     1561 aagaaaggac ttgtggatct atcttgtgct ctatatcctg gggttaggcc atttaaaata
     1621 gaattggcag gatcggattt catgatttga taacaatttt gacagagatc aacctgtctt
     1681 tgttttccat taacacttgt ataaagatga atagtagatt cgtttaaatt acaattttga
     1741 cacagcataa tatacctccg agggtttatc taaaagtcaa agtcatttag tcaaaaatgg
     1801 tcaaacttta tattcatatt atagcaccac ggcttgggaa atcaagtaaa aagtttatcg
     1861 ctttagcgtt agcttttaga gagtaacatg acagagtaac tttattaagt ttccaatgag
     1921 caaatgttta aaatcattga aaagagtaaa aaaagtaaaa tatcaataaa tatattactt
     1981 tccttgttag tttcccttgt tttgtgttaa aataagaggg ataaaaaacg aataggagaa
     2041 acgaaatgga atcacatttg gtgagaatca tcaatcgttt ggagttgatg gtgacagatg
     2101 gcggtaatct caagcgaaat tttgaacgcg atggtgttgt tgttgcagaa gttgcctttt
     2161 caaatgatcc tgaaaatgga cctgttttca cattgcgtga tgttgaagcg cgtgagtcat
     2221 attcctttga tagtattgac ttaattgcaa tggaaatcta cgatttatta tattaagctt
     2281 gacatagtaa agagacttgc ctgaggcagg tttttttatt gtcaaaaagt attgtattaa
     2341 tattcatcag atggtataat tatctttatt gtaatgaacc taggacttat gaggagatat
     2401 aaatggattt gtcatttttg cccaaatact gggcctactt taactacggt gtacttgtca
     2461 ccattatgat ttcagtcagc gttgtctttt ttggaaccct tattggtgtc ttggtaaccc
     2521 tgattaagcg tagtcatgtg aagccgttga cctgggtcgt taatctttac gtttggatct
     2581 ttcggggaac acctatggtg gttcaaatca tgattgcctt tgcttggatg cattttaaca
     2641 atatgcctac tattggtttt ggggttttag acttggactt ttcaagacta cttcctggaa
     2701 ttattatcat ttcattgaat agcggtgctt atatttcaga aattgttaga gcaggtattg
     2761 aggctgtacc aaaagggcaa ttagaagcag cttattcact aggtattcgt cctcaaaatg
     2821 ccatgcgtta tgtgattttg cctcaggcct ttaaaaatat tttgccagcc ttaggaaatg
     2881 aatttattac cattattaag gatagtgctc ttttacaaac cattggagtg atggaacttt
     2941 ggaatggtgc ccaatcggtg gtaacggcta cttattctcc aatttcccct ttactggtgg
     3001 ctgcttttta ctacttaatg gtcacaacag tgatggcaca gttattggca gtcttagaat
     3061 gtcacatggc gcaaggaggt aatcattgat gactgaggct attatttcaa ttaaagactt
     3121 gcacaagtat tatgggcaca atgaagtgct taagggaatt gatttagaca ttatgccagg
     3181 agaggttgtg gtgattattg gcccttctgg ttctggaaaa tcgaccttac ttcgaactat
     3241 gaatcttttg gaagtaccaa ctaagggaca gattaggttt gaggggattg atattaccga
     3301 taagaagaat gatattttca gcatgcgtga aaaaatggga atggttttcc agcagtttaa
     3361 cctctttccc aatatgacta ttttagaaaa tatcacttta tcgccaatca aaactaaggg
     3421 aatggctaaa gcagaggctg acaaaacagc cttgagcttg ttggacaaag ttggattatc
     3481 agaaaaagcc aaggcttatc ctgctagtct ttctggtggg caacagcagc ggattgcgat
     3541 tgcgcgtgga ctggctatgg atccagatgt tttactcttt gatgaaccaa cttcagctct
     3601 agacccagaa atggtgggtg aggtcttggc tgtcatgcaa gatttggcta aatctgggat
     3661 gactatggtt attgtgactc atgaaatggg ctttgctaaa gaagtcgcag accgtgtgat
     3721 ttttatggat ggcggcgtta ttgtggaaga aggaagtcct aaccaacttt ttgatctgac
     3781 taaagaagaa cgtacaaaag attttttgag tagagtatta taaatctgtt ctatgaatta
     3841 taaaaggaag tcctaaatga tttaggactt ccttttataa tttgctaagg cattttatag
     3901 gagattactt ttctttttgt taaaataaaa agaaatagtt gcattatttg catagaagaa
     3961 agggatctgt tatggtttca gtgatgtggt ttcgtagaga tttaaggatt gatgatcaaa
     4021 aagctttagc tcatgctatt gctagtcaat caccaacctt atgtgtgttt caatttaaca
     4081 aggagcaatt aaatctgcta catagtcgga atcaatctag ttttattact agcgttttgg
     4141 cttttagaaa gttattaaaa tgtgaaggta ttgacttata tctaatgtat ggagacttaa
     4201 tgacctgttt tgagcaatta ttgacacaat taaaagactg gacagatgtg tattttaact
     4261 atgatgaatc tggatatggt cgtttacgtg atcaaaaagc agcacaattt ttcaaaaaaa
     4321 atgggattgc tgttcatacc taccaagatc actatttaca tggtagtcaa gagatcatta
     4381 accaatcagg tcagccttat aaagttttta cgccctacta taggatttgg caaaattatc
     4441 cgaaagagac tcctattaaa gtagaactat cgcaaggcag gtggttaaat cttgagacac
     4501 cagatgatgt tttaaggact gttgagagct ttaaagatga aaaatatcag gatgttgcaa
     4561 cttttgatga agcgtcaaaa caactaaatc gatttattca agaccaatta gcagcttatc
     4621 acgctaatcg agattttcca gcgcagctag ggacgagtcg gttgtctccc tttttaagaa
     4681 taggagctat tggcattcgc acggtatatc acgctgtgcg tcaagcacca aatagtctag
     4741 ggcaagctac ttttttaaaa gaattagctt ggagagactt ttacaatatg gtctatgtgg
     4801 cttatcctga tcagaaaact cagcctatcc aaaaagcctt ttctcaaatc gaatgggtta
     4861 ataatcctga ctggtttcag ttgtggaaag aaggtaaaac gggttaccct attgttgatg
     4921 ctgccatgct tcagttacaa aagacaggat ggatgcataa tcgtttacga atgatagtag
     4981 cttctttttt aactaaagat cttttatgtg attggcgttt aggagagcag tattttcaac
     5041 aacaactaat tgattatgat gctgccagta atatcggagg atggcagtgg gctgcttcca
     5101 ctggaacaga tgctgttcct tattttagaa tatttaatcc tgttactcaa ggtaagcgtt
     5161 ttgatcccaa aggcgagttt attaaagcgt atttgcctca actagaacac gttccagaga
     5221 agtatctcca cgaaccgtgg aagatgccaa aataccttca agagagtgta tcctgtatta
     5281 ttggcacaga ctatcctcaa ccaattgtcg atcatgctaa acaacgtgaa caagctattg
     5341 caaagtatga gtgggcaaaa gaaaaagcaa aaatagaatg actgttctca ttataagagt
     5401 ttaaacaaaa agttatcatg aattaagatt atttaattta aaaaacaagt tgactttatt
     5461 tagattattt gatactattc agttgtctcc cttagagaaa gcgatttctt gttttggagc
     5521 tgatttttac catttggtct tagaatagga tgagtaatat gacttacaac gaggtatatc
     5581 aagaatggtt gcacaataat gatcttagtg atgatattaa agcagattta gcagccataa
     5641 aagacaatga ggctgagatt caagatcgtt tttacaaaac acttgaattt ggaacagcag
     5701 ggctaagagg aaaacttgga gcaggcacca atcgcatgaa tacctatatg gttggtaagg
     5761 cagcacaagc tttagctaat actattattg atcatggacc tgaagcagtt aaaaagggca
     5821 ttgcggttag ttatgatgtt cgctatcaat ctagaacatt tgcagaatta acatgctcta
     5881 ttatggcagc taacggtatt aaggcgtacc tttataaagg gattcggcca acaccaatgt
     5941 gttcgtacgc tattcgtgct ttgggatgta tctctggtgt tatgattacg gctagtcaca
     6001 atccccaagc ttacaatggt tacaaagctt attggcaaga aggttctcaa attttggatg
     6061 acattgcgga tcaaattgca caacacatgg ctgcactaac tcagtatgag gaaatcaaac
     6121 aaatgccttt tgaaaaggct ctggacagtg gacttgttac ttatattgat gagagtattg
     6181 aagaagcata taaaaaagaa gtgcttggtt taacgattaa tgatactgac attgataagt
     6241 cagtccgagt agtctatacc cctttaaatg gtgttgggaa tctaccagtg cgtgaggttt
     6301 taagacgccg cggttttgaa aatgtttatg tggtacctga gcaggaaatg cccgatcctg
     6361 attttacaac agttggctat cctaatcccg aagtccctaa aacttttgca tattcagaaa
     6421 aattaggtaa ggcagttgat gctgatattt tgattgcaac tgatccagat tgtgaccgtg
     6481 tggctttaga agttaaaaat gcagtcggtg actatgtttt tctcaatggc aataaaatcg
     6541 gagcgctttt atcttactat atcttttcgc aacgatttga cttaggcaat ttaccggcta
     6601 atcctgtttt agtgaaatcc attgtaacag gagacttgtc acgggctatt gctagccatt
     6661 atggtattga aaccgttgaa acattgactg gttttaagaa tatttgtggc aaggcaaacg
     6721 aatatgatgt gacgaaacag aaaaactacc tgtttggtta tgaagaaagt attggttttt
     6781 gctatggcac ttttgttcgt gacaaagacg ctgttagcgc ctctatgatg attgtagaaa
     6841 tggcagctta ctacaagaaa aagggacaga atttactaga tgttttgcag actatttatg
     6901 cgacatttgg gtattataat gaacgtcaaa ttgccttgga gcttgagggg atagaaggac
     6961 aaaaacgcat tgcgaggata atggaagatt tcagacagac accaatagct agtgttgcag
     7021 agatggcgtt agacaagaca attgatttta ttgatggcta tcaagatttt ccaaagcaaa
     7081 actgtctcaa attttatttg gatgatggtt cttggtatgc acttagacca tcaggaacag
     7141 agcctaaaat aaaattttat ttatatacta ttggccaaac acaagaaaat agtgcaacaa
     7201 aattagatgc tattgaagca gcatgtcgca caaaaataaa tcaggttaat taaacatcaa
     7261 aaatggataa cacttttaca ctatttttcc atataaacaa ctacaaaagg aggtgagact
     7321 tttaggcacc ttctttttct tgtaggtgcc actaatcaat ttaatcgact caaaccaata
     7381 ctaaaaaata agtaagagta taaagaacag gcatctattt ttttgttata atagaaaaat
     7441 gaaattaaag ggagatgtca atgacagaac taattgatgg taaagcctta gctcaaaaga
     7501 tgcaacaaga gttagcagct aaagtcaaca atctaaaaca aaaaaaagga attgtaccag
     7561 gcttagccgt tattcttgta ggtgatgatc ctgctagtca ggtgtatgtc cgtaataaag
     7621 agcgtgcagc tcttactgta ggttttaaaa gtgagaccgt tagattatca gaattcattt
     7681 gtcaagaaga gcttattgca gtaatcgaac gttacaatgc agataacact attcatggta
     7741 ttttagtgca gctacccctg ccaaatcata ttaatgataa aaaaattatt ctcgccattg
     7801 atcccaaaaa agatgtggat ggttttcacc cgatgaatac aggtcacctt tggtcaggac
     7861 gtcccttaat ggttccttgt actccatcag ggattatgga attgcttcga gaatataatg
     7921 ttaaccttga aggtaaacat gccgtcatta ttggcagatc gaatatcgtt ggaaaaccaa
     7981 tggcacagct cttactagac aaaaatgcaa cagtcacgtt gacacattca agaacacgtc
     8041 aattagaaga agtatgtcgc tgtgcagatg tgttgattgt ggcaatcgga caaggtcatt
     8101 tcataacaaa acaatatata aaagagggtg cgatagtgat tgatgtggga atgaaccgtg
     8161 atgataatgg caagctaatt ggagatgtgg cctttgatga ggtggcagaa gttgcagcga
     8221 aaatcacccc tgtaccagga ggtgtcggtc ctatgacgat tgctatgttg ctagagcaaa
     8281 cttatcaatc tgctctccgt agtactcata aatagttatc attagacaat tcaacataag
     8341 agaatataag aagtcagcaa tggcttcctt ttttgttttt ctgctcacta tttattcaga
     8401 aaaatggtat aattgcatta gtatgcaaag ggactatgtc aggtccaact aagtgaaagg
     8461 tggcttgatg gcagattatt taaccgtcac tcatttgacg aaatatttaa aattaaaatt
     8521 tgaccgtgac ccttatttgg aacgggttta tctgactggt caagtgtcca attttcgaaa
     8581 acgaccaact catcaatatt tttccttaaa ggatgaaagt gctgtgattc aagccaccat
     8641 gtgggcagga gtctataaaa aactaggatt cgacctagaa gaaggcatga aaattaatgt
     8701 aattgggcga gttcaacttt atgaacctag tggctcttac tctatcgtga ttgaaaaggc
     8761 agagccagat ggtataggtg ccttggcttt gcagtttgaa caattaaaga aaaaattaac
     8821 ggcagaaggt tattttgagc aaaaacacaa gcagcccttg ccacagtttg tatcaaaaat
     8881 tggggtcatt acaagtccta gtggtgctgt gattcgagat attatcacaa ccgtttcacg
     8941 gcgttttcca ggggttgaga ttttattatt cccaactaaa gtacaaggtg atggagccgc
     9001 ccaagaagta gtggctaata ttcgaagagc caatcaaaga gaggatttgg acttgctcat
     9061 tgtcggccgt ggaggtggct cgatagaaga cctttgggcc ttcaacgagg aaatagtggt
     9121 tcaggctatc tttgaatcgc aacttccagt gatttcgagt gtgggtcatg aaacagacac
     9181 gactttagcg gattttgtgg cagatcgcag agcagccaca ccaacagcag cagcagagtt
     9241 agcaacgcct attacaaaaa cagatcttat gtcttggata gtagagcggc aaaatcgttc
     9301 ctatcaggcc tgcttgaggc ggattaagca acggcaagag tgggtggata aactctcgca
     9361 atctgttatt tttaggcaac cagaacgatt atatgatgcc tacctgcaaa aaattgatcg
     9421 ccttagcatg accctgatga atacgatgaa agatcgtctg agttccgcca aagaaaacaa
     9481 ggttcagttg gaccatgcct tggccaatag tcaattacag acaaaaatcg agcgatacca
     9541 agaccgtgtt gctaccgcta agcgtttact gatggctaat atggctagtc aatatgatag
     9601 tcagctggct cgctttgaaa aagcacagga tgctttgcta tcactggatg ccagccgaat
     9661 tatcgcccgt ggttatgcaa tgattgaaaa aaatcaagca ctggtagcct ctgtaagtca
     9721 gataacaaag ggtgatcagt taaccattaa gatgcgtgat ggacaattag atgtagaggt
     9781 aaaagatgtc aaaaacgaaa acatttgaag aaaatttaca agatttagag actattgtga
     9841 acaaacttga aaatggggat gtccctttgg aagaagctat ttcagaattt caaaaaggaa
     9901 tgcttctctc aaaagaactt caaaagacct tacaagcggc agaaaaaaca ctcgtcaaag
     9961 tgatgcaagc tgatggcaca gaagtagata tggatgatta atggacaaat tagctagaat
    10021 tgacgaagcc attcgtcgct actataagac gactagtaac ggtgtatctg aagagttgat
    10081 tgatgctatc ttgtattctg ttgacagtgg tggcaagcgc attcgaccac ttatcttatt
    10141 agagatgatt gagggatttg gggtatcgtt acagaatgct cattttgatt tggctgcagc
    10201 ccttgaaatg attcatacag gaagtctgat tcacgatgat ttgccagcca tggataatga
    10261 tgattaccga cgtggtagac tgaccaatca caaacaattt ggagaagcca cggccatttt
    10321 ggcgggagat agcttatttt tagacccctt tgggttaata gctcaagctg aattaaatag
    10381 cgaggttaaa gtagccttaa tccaagaact ttccctagct tcaggaactt ttggcatggt
    10441 tggtggtcag atgctagata tgaaagggga aaatcaagct ttgagtctcc ctcagttgtc
    10501 actgattcac ctcaataaaa ccggaaaatt attaactttt ccttttaaag cagcagctct
    10561 tgtaacagac caggctatta ctgttcgtca acaactagag caggcgggaa tgctcatcgg
    10621 gcacgccttt cagattaggg atgatattct agacgtgaca gctagctttg aagatcttgg
    10681 aaaaacgcct aaaaaggatt tatttgcaga aaaagctact tacccaagtt tactggggtt
    10741 agaagcctcc taccaactgt tgacagagag tttagatcag gctttgacga tttttcagac
    10801 actagaaaac gatgtaggct ttaagcctca aataattaca aaactgatag aagggttacg
    10861 acttaatgcc taaagaaaga gtagatgtgt tagcctataa gcaaggatta tttgagacca
    10921 gagagcaagc taagcgtggt gttatggcag gcctagtggt ctctgtgatt aatggccaac
    10981 gctatgacaa gccaggtgac aaaattgacg atgggactga gttaaaactt aaaggtgaaa
    11041 aactcaaata cgtcagtcgt ggtggattaa aactggaaaa ggggctgcac gtttttggtg
    11101 tatcggttgc taatcaaatt gggattgaca ttggcgcttc aacaggtggt tttaccgatg
    11161 ttatgttaca agatggggcc aaactagtct atgccgtcga cgttgggact aaccagttgg
    11221 tatggaaact cagacaagat ccacgagtaa gaagtatgga acagtataac tttcgttatg
    11281 ctcagccaga ggactttagt gagggacagc ctgtatttgc cagtattgat gtgtccttta
    11341 tttctctcaa cttgattttg ccagccctgc ataacgtttt gtcagatcag ggacaggtta
    11401 ttgctctcat taaaccgcaa tttgaagctg ggcgcgagca gattggtaaa aaaggcatcg
    11461 tcaaagacaa acagattcat gaaaaagtga ttcaaaaggt catggatttt gcctcaggtt
    11521 acggatttac agttaaggga cttgattttt cccctattca gggtggtcat ggaaatatcg
    11581 aatttttagc tcatcttgtt aagtcacaga cacctgaaac gttagcccca catctgattc
    11641 aggaagttgt tgccaaggca cataaggagt ttgagaaaca tgaaaaaaag tgaacgactt
    11701 gaattaatca aaaaaatggt tttgacgcat ccaattgaga cgcaacatga cctcttaaga
    11761 ttattggcag agcatgggtt agaattaacc caggctacta tttcaagaga catgaatgaa
    11821 attggtatag taaagattcc ttctggcagt ggacgttaca tctatggtct ttctcaagat
    11881 agtggaaaaa agatcgttca aggacctaga tcgataaaga gcactatttt agctgtatct
    11941 gacaaaacaa aaggtttaga acaacacctc tatttaaaag tcgtacctgg caatagtaaa
    12001 ttaatcaaac gttatttatt agcagatttt tcaaaagcta tttttagtct tattgctgat
    12061 gatgatagtt tattgttaat tgcaaagtct ccttcagaag cagatatgat acgccaagaa
    12121 attttgcttt ggatgcaggg tataacctag aaaaaaatag gggagaaagt gatgttatta
    12181 gaaatttcta ttaaaaattt tgctattatt gatgaaattt ccctaaattt tgaaaatggt
    12241 atgacggttt tgacgggtga aactggagca ggaaagtcta ttatcattga tgctatgaat
    12301 atgatgcttg gtgcgcgtgc tagtacagaa gtgattcgtc gtggagctaa taaagcagaa
    12361 attgaggggt tcttttcggt agatgctacc ccagaactgg ttgcgtgtct ggaatcatca
    12421 ggtattgcta tggaagaaga actgattatt cgccgagata tctttgccaa tggcagaagc
    12481 gtgagccgca ttaatggtca gatggttaac ctagctacct taaaacaggt cggacagttt
    12541 ttggtagata ttcatgggca acatgaccaa gaagaattaa tgcgaccaca gctccaccag
    12601 caaattttgg acgcttttgg tgataaggct tttgagcaat tgaaagagaa ctatcagctt
    12661 atttttgatc gttataaaag cttgcgtcgc caggttattg acaaacaaaa aaatgaaaag
    12721 gaacacaaag atcgtattga tatgttggcc tttcagatag cagaaattga agctgctgcc
    12781 ttgagtcgag gtgaggacga ccggttaaat caagaacgtg atcgcttaat gaaccacaaa
    12841 caaattgctg ataccctgac caatgcctac gtcatgctag ataatgacga tttttcaagt
    12901 ctatccaata ttcgctctag catgaatgac ttactatcaa ttgagcagtt tgattcagaa
    12961 tacaaaggga tgtcgacttc gatttctgaa gcctattata ttcttgaaga agtgagcaag
    13021 caattatcag ataccattga ccaactggat tttgatggtg ggcgattaca ggaaattgaa
    13081 tttcgcttgg atacactcaa tagcttaacc cgtaaatacg gtggtaatgt gaatgatgtg
    13141 cttgactact acgataatat tatcaaagaa taccagctat taacaggaga tgacttgtct
    13201 tcaggggatc tagaggcaga attgaaagcc ttagaaaaac aattggttgc tgcagccact
    13261 aacttgagtg aacgccgcca tcaattggca gagcaattag aagctgagat taaagctgaa
    13321 cttaaggaac tttatatgga aaaagcagat ttcaaagttc actttaccac atcaaaattc
    13381 aatcgtgatg gtaatgaaag cttggaattt tacatctcta ctaatccagg cgaaggattc
    13441 aagccccttg tcaaggtggc ttctggagga gagttatcac gccttatgtt agccatcaag
    13501 gctgctattt ctagaaaaga agataagacg agtattgttt ttgatgaagt agatacaggt
    13561 gtttctggtc gcgttgcgca agccattgcc caaaaaattt ataaaattgg gcgacatggg
    13621 caagttctcg ctatttcaca cttacctcaa gttattgcta ttgctgatta tcagtatttt
    13681 atttctaaag aaagtaaaga agagtccacc gtttctaagg taaggttatt aactcctgaa
    13741 gaacgtgtgg aagaaattgc tagcatgatt gcaggaacag atatgacaca agctgctctt
    13801 acgcaggctc gtgaactact tgccaaacat taagattatg tttggtattt gatattttca
    13861 taattagatg acattgattt tttaggtgtt aaaataatca ttgtgtcaga ccatttttcc
    13921 tctgttaatc tggcttggtt tgccttgaca aacctctgag aaatagtaga atagataaga
    13981 gaattttaag ctgaggggat agaaatgact agtaaaaaag cgtgtttatc aagcatcatt
    14041 gtgttagcaa gtttaacgtg tggaaatgat actgttagtg ccaatcatct ctcagcaact
    14101 ggagataagt ttgatgattg ctcaacactt gttgaaaaag atgtggcccc taaagatgaa
    14161 cttgagatgt tagcatggtc ctcgtctcaa acaactgatg atgctgacag agactatgaa
    14221 gattttctcg atgatgattc ttttaatgat gattctttta atgatgattc ttttaatgat
    14281 gattctttta tttctcaaaa tgaaactgat aagatgtttg agaatttaac tgatgatagg
    14341 ttattagatg aattagatga agaagataca attgagccag agcaaaatgt aataatgcct
    14401 agtgacgatg agctatttga tttaactgat gctgttgaga cacgccttac tgtttctagt
    14461 gctccccatt tagaggctga attgccgaaa ccacatttga ggagcctatc agatacagca
    14521 ctgcggtctg gtgaaattag aggacattta gataacaaac tggacgcttt gtctgtaaca
    14581 gctacaaagt tagcattaac gatggctcaa aaatttgatt tgacaacgca tgtctattct
    14641 ataggtgaaa gctttagtga agtattagct gctcattatg aagatagaaa agcagaatca
    14701 gctttttcta agaaaaagag atttcacctt cctattgcta ctccagatgt tgttatagag
    14761 gagttaaggc gcctagtctc ttctattgga agttcaaaag aagatgtttc agttccttat
    14821 aatcggaagc taggtatggc agttgcaaaa agaaaaatag ccctgccaca aacgggagag
    14881 gggttctctt attatccagc tttacttggt ttaatgatat taggattaac gccgattatg
    14941 ataccaaaga agataaataa ttaggtaata agttattgta gttgtaaaaa acggggcaaa
    15001 tgttcaagcg tgaaaaggtt gacttttgcc tcgttttgta tctcgttatt gctaaggcat
    15061 tttcttcgag cagctagtgc tcgccatacc tatctaccga gtgattattc aatagcacta
    15121 ccagttttgc tttatttagt aaggagtgtt agaataaaga ggtgagaaac tagtttagaa
    15181 tggaaaaata catgggaact ataaaaattg ttacagattc atcaataact attgaaccag
    15241 aattaattaa agctttagat attactgtag tgcctttatc tgtcatgatt gatagcaaat
    15301 tatactctga taatgattta aaagaagaag gtcatttttt gagtcttatg aaggctagca
    15361 aatcccttcc caaaaccagt cagccaccgg ttggtctctt tgctgaaact tacgaaaatt
    15421 tggtcaaaaa aggagtaact gacattgttg ctattcacct ctcaccagct ttatcaggta
    15481 ctattgaagc ttcccgtcag ggggctgaaa tcgctgaggc acctgttaca gttttagatt
    15541 caggatttac tgatcaagcc atgaaatttc aggtcgttga ggcagcaaag atggcaaaag
    15601 cgggtgctag tttgaatgag attttggctg ctgttcaagc tatcaaatca aaaacagagc
    15661 tctacattgg tgtatctacc ttagaaaatt tagtaaaagg aggtcgtatt ggtcgtgtga
    15721 cgggtgtttt gagctcgcta cttaatgtca aagttgttat ggcacttaaa aatgatgagt
    15781 taaaaacgct tgtcaaaggt cgaggtaata aaacatttac gaaatggtta gatagttacc
    15841 tcgctaaaaa tagtcatcgc ccgattgcag agatagctat ttcttatgct ggtgaagcta
    15901 gcctggcatt aaccttaaaa gaaagaatcg cagcttatta caaccactct atttcggttt
    15961 tagaaacagg ctctatcatc caaacacata caggagaagg agcttttgcg gttatggttc
    16021 gttatgaata atcgtcattt atttagtggg atatttttct ttgttattag tttatgtctg
    16081 gcctttttat tgctaaatat tattatccct aagtcaaatt catgtttgaa aaagagtgat
    16141 tttctgaaaa aagaacaagt agctatccaa tatgttgcta taggagactc attgacagaa
    16201 ggagtaggtg atctaactca tcaaggtggt tttgttcctt tgttaacgaa tgatcttagt
    16261 gaatatttta aggctaatgt taatcatcaa aattacggcg tatctggtga taccagtcaa
    16321 caaattcttg ataggatgat aaaacaaaag cagatacagt tatctttaaa aaaagcagat
    16381 ataatgacgt taaccgttgg tggtaatgat gttatggcag ttattcggaa gaatttagcg
    16441 gatttgcaag tttctagttt tagaaagcca gctcgtcagt atcaaaaacg attaagacag
    16501 attatcgagt tagccagaaa agataataaa gatcttccta tttttatttt aggcatctat
    16561 aatccgtttt atttgaattt tccagaacta actgatatgc aaaaagtgat tgatgactgg
    16621 aataccaaaa ctaaggaggt tgttggagaa tacgatcgtg tgtactttgt gccaataaat
    16681 gacctcttgt ataaagggat aaatggacaa gaaggaattg tccattcttc aggagatcaa
    16741 actacaattg tcaatgatgc cttgtttact ggggaccatt ttcacccaaa taatactggc
    16801 tatcaaatca tgtcaaatgc agtaatggag aaaataaaaa agcatgaaaa aaaaatcaaa
    16861 ccttaattgg tggaagtgga gcttcttatg tctgcttgct tttaataccg cctttttgat
    16921 ggttattgca agtcgtctca ttcaagtaag agaacctgag tcagaactga ttgctaaaaa
    16981 accagttaaa aatatcaaaa ttggtacatt tgtcacaacc agagaacagc ttaacgaaac
    17041 tgtagcaagt tatcttaaag attatcagac taaaaaaatg tcttataaat tttatgcgac
    17101 atcttcttct attttgtttg aaggaactta tcaattatta gggtatgaag tccctttata
    17161 tatctatttt caacctcatc gtctagaaaa tggagctgtc caactacagg tgatctcttt
    17221 ttcagtggga actctgccac tcccagaaaa agatgttttg cagtatttga aatcaagcta
    17281 caaattgcca agctttgtta aagtgatgcc aaatcaatca gctatcgttg ttaatttaca
    17341 agatatccaa aatgatgcta aggtttattt aaaggccaag aaaattgatt tatttaatga
    17401 tgaaatcagt tttaacatct ataagaaata agctcaaata acgttaaata cttgacctaa
    17461 tcgctttttt tagatatgat aatatctgtt aaagcattaa gcttactaat tatttggagg
    17521 atttgttaaa tggctaacaa acaagattta atcgcaaagg ttgcagaagc aactgaattg
    17581 actaaaaaag attcagcagc agcagttgat gccgtgtttt ctacaatcga agctttcctt
    17641 gctgaaggtg aaaaagtaca attgatcggt tttggtaact tcgaagtacg cgaacgtgca
    17701 gctcgtaaag gtcgtaaccc acaaactggt gcagaaattg aaattgcagc ttcaaaagtt
    17761 ccagccttca aagctggtaa agctcttaaa gacgctgtta aataattcgt ctagaaaaat
    17821 cttgttgcta tcgatgttta ttgatagcaa caaggttctt tttttatatt tggggcataa
    17881 agttagtagt tttctcttca gttaagccaa gttctaaagc atgcactcta taatggtcag
    17941 tcatccttct attagtatat catttccgca ggtaggggga gtttttttca tatttgcaaa
    18001 tagttgaagt taggattttt gaaagcaaaa ggtaagttta aaaaagttta tttagaatgt
    18061 ttctaaatta cttgacttat ttatttagaa ttattataat taatatatct taaagattga
    18121 ataactttta attgcgaggg aactaaaaat gacaatcaga caatggatgg cagaccatct
    18181 tcatttgatg gagactttag cgtgtttggt attaataata attggcctag cctttttaca
    18241 ctcatttcca caagtggctt ccgctatttt cattacagcc ttcttgattg gaggatatgc
    18301 gtctgcaaaa acgggtatat tggatttggt gaagaacaaa cacttgtcag tggatatttt
    18361 gatgattttg gcagctatcg gtgctggaat tatcggctat tggctggagg gtgctctgct
    18421 tatttttatc ttttcgttgt ccaatacgct tgaagaaatg gccatggaaa aaagtaagga
    18481 tgctatttca gccttgatgt ccttgacgcc agatacagct cgtcaatacc aagaagatgg
    18541 ccatatttta gaagttgaga ccagatcctt gagtgttggt gaccgtttac aagttcgtaa
    18601 aggcgaagct gttccaattg acgggcagtt gcttagtcct tttggtcaat ttgatgaatc
    18661 tatggtcact ggtgagccta tcactgttga taaggcagaa ggccaggatc tgattggggg
    18721 aaccattaac caaggacaaa ccatagatat gttggttact attgaaaatg acgatactct
    18781 ctttgccaag attattaatc tggtggaatc tgcccaagaa aagaaaagca aaaccgccac
    18841 ctttatcgaa agcttagaag atggttatgt caaatttgtg ctcgtcctta ttcctgcctt
    18901 tatcctcttt agccactttg tgcttttttg gacttggttg gctgcttttt accgagggat
    18961 gattctctta acagtagctt caccatgtgc cctaattgcc agttccacac ctgctagctt
    19021 ggctgctatt tctcgtgcag ccagaaaggg attgattatc aaaggagggg atattgtcga
    19081 taacatggga gatattaagg ctgttgtcat ggataaaacg ggaacgctca cccaaggaaa
    19141 accttctgtt gtgaatgctc attatttgga agatgagttg ctcgtgaata gactggtaaa
    19201 aggagcagag actgctagta cccatcctat ttctaaagcc cttcttgaat acactgaaaa
    19261 attggagcca ctgacctttg accacttaga agaaatttct gggaaaggtt ttcagggctt
    19321 ctatcaaggg caagaatggc gaattggcaa gaaaaccttc attttggaaa aggttcaaga
    19381 cctatcagct tttgaagaaa ctattcaagt ggaagaaaat caagggaaaa ccctaatctt
    19441 tgtttcacgt gaccatcaat tgatagctta ctatgccctc ttggatgata tcaaaataga
    19501 atcaaaacgt gctattaagt ctcttcatgc catgggaatc aaaacagtca tgttaacagg
    19561 tgaccaagaa cgaaccgcca attatgtggc acaaaaactt ggtattgatg aagtggtagc
    19621 caactgtatg cctcaagata aggtggctaa gttagcagaa ttaaagacta aatatggttt
    19681 tgtggctatg gtaggagatg gtattaatga tgctcctgcc cttgctcaag cagatgtttc
    19741 ttatgctatt ggatcaggaa cagatattgc aatggaaagt gcagacagtg tgattatgga
    19801 tgacttgact cgtattccat tttcgattca actttcccgc aaaatgaaga ccattatcaa
    19861 acaaaatatt gtttttgcct tatctgtgat taccttattg attttagcca atgtttttca
    19921 ggtagttaac ttgccgcttg gtgttgttgg acacgaaggc tcaacgattt tagtgatttt
    19981 aaatggcttg cgtttacttt cttttaaata atttagaaac ttgcttgaaa acttgaaagt
    20041 gtttataata atagtaagac ttatgaaaga gaaaaccgcc gtatgtttac tattatgatc
    20101 attggtttag ctgtattttc aataattaaa atcattctat ttttctattt ttatcagcaa
    20161 tttgagcgca agcaaaaaag aaaagttgaa tcaaacaacc agcaaagaca gtcccaagaa
    20221 agtgacgctg tcctttcaaa aaaattccca ttttaaaaag cttggaaagt gtacaaagtg
    20281 cacatttcca agcttttttg actattaagg ttaatctttg taacgtaagt tcccacgaaa
    20341 atcgtctaag ctttggtagc ctttttctac cataatcgtt tttagttcct tagtgacccg
    20401 ttcaaagata gctggccctt cttgatgaag ggctgtccca atttggacca tgctggcgcc
    20461 acaaagaata tgttcaaagg catcgcgtcc tgttttaact ccccctgtac caataatgtg
    20521 gatagaaggt tttaagcgtt tgtaaaacgc atggacattg gctagagcag taggtttgat
    20581 gtaatctcca cctataccac caaagccatt tttaggcttg atgaggactt gttcatcctc
    20641 aatgaccagc ccatttccga tagaattgac acagttaaca aaggaaaggg ggtatttatt
    20701 gaaaatcgca gccgcttgat caaaatgcac aatgtcaaaa taaggaggta atttgatacc
    20761 aagaggttta gtgtaatagg taaagatgtt ctctagaagt tgatcagtgg tttcaaaatc
    20821 ataagcaatc tgtggttttc ctggaacgtt agggcaagaa aggtttagtt cca
//
