LOCUS       NZ_CP035440            41176 bp    DNA     circular CON 15-OCT-2024
DEFINITION  Streptococcus pyogenes strain emm124 chromosome, complete genome.
ACCESSION   NZ_CP035440
VERSION     NZ_CP035440.1
KEYWORDS    RefSeq.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1790668)
  AUTHORS   Davies,M.R., McIntyre,L., Mutreja,A., Lacey,J.A., Lees,J.A.,
            Towers,R.J., Duchene,S., Smeesters,P.R., Frost,H.R., Price,D.J.,
            Holden,M.T.G., David,S., Giffard,P.M., Worthing,K.A., Seale,A.C.,
            Berkley,J.A., Harris,S.R., Rivera-Hernandez,T., Berking,O.,
            Cork,A.J., Torres,R.S.L.A., Lithgow,T., Strugnell,R.A., Bergmann,R.,
            Nitsche-Schmitz,P., Chhatwal,G.S., Bentley,S.D., Fraser,J.D.,
            Moreland,N.J., Carapetis,J.R., Steer,A.C., Parkhill,J., Saul,A.,
            Williamson,D.A., Currie,B.J., Tong,S.Y., Dougan,G. and Walker,M.J.
  TITLE     Atlas of group A streptococcal vaccine candidates compiled using
            large scale comparative genomics
  JOURNAL   Nat. Genet. (2019) In press
REFERENCE   2  (bases 1 to 1790668)
  AUTHORS   Davies,M.R., McIntyre,L., Mutreja,A., Lacey,J.A., Lees,J.A.,
            Towers,R.J., Duchene,S., Smeesters,P.R., Frost,H.R., Price,D.J.,
            Holden,M.T.G., David,S., Giffard,P.M., Worthing,K.A., Seale,A.C.,
            Berkley,J.A., Harris,S.R., Rivera-Hernandez,T., Berking,O.,
            Cork,A.J., Torres,R.S.L.A., Lithgow,T., Strugnell,R.A., Bergmann,R.,
            Nitsche-Schmitz,P., Chhatwal,G.S., Bentley,S.D., Fraser,J.D.,
            Moreland,N.J., Carapetis,J.R., Steer,A.C., Parkhill,J., Saul,A.,
            Williamson,D.A., Currie,B.J., Tong,S.Y., Dougan,G. and Walker,M.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2019) Department of Microbiology and Immunology,
            University of Melbourne, The Doherty Institute of Infection and
            Immunology, Melbourne, Victoria 3000, Australia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 80x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_005161825.1-RS_2024_10_13
            Annotation Date                   :: 10/13/2024 02:09:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,746
            CDSs (total)                      :: 1,657
            Genes (coding)                    :: 1,595
            CDSs (with protein)               :: 1,595
            Genes (RNA)                       :: 89
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 36 of 62
            Pseudo Genes (incomplete)         :: 33 of 62
            Pseudo Genes (internal stop)      :: 16 of 62
            Pseudo Genes (multiple problems)  :: 18 of 62
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:05:44
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1061157
            Orig. end                         :: 1102333
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP035440.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..41176
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="T3PKS"
                     /region_number="3"
                     /rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /tool="antismash"
     cand_cluster    1..41176
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /kind="single"
                     /product="T3PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..41176
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:21176](+)"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..21176
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
     gene            complement(702..1352)
                     /locus_tag="ETT59_RS05395"
                     /old_locus_tag="ETT59_05395"
     CDS             complement(702..1352)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057640.1"
                     /locus_tag="ETT59_RS05395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT59_05395"
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_003061805.1"
                     /transl_table=11
                     /translation="MINIPLMKDSLGFVLSGLPYTLGISLLSFFTGLFLGLGLALLGRS
                     RQPLIHYLVRAYISIMRGVPMIVVLFVLYFGLPYYGLELPALLCAYLGFSMVSAAYISE
                     VFRSSIEAIDKGQWEAAKALGLPYALMVKKIILPQAFRIAVPPLGNVIIDMVKSSSLAA
                     MITVPDIFQNAKIIGGREWDYMSMYILVAFIYWLIAFLLERYQEFLENKLALV"
     gene            complement(1381..2244)
                     /locus_tag="ETT59_RS05400"
                     /old_locus_tag="ETT59_05400"
     CDS             complement(1381..2244)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061079.1"
                     /locus_tag="ETT59_RS05400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT59_05400"
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="WP_002990133.1"
                     /transl_table=11
                     /translation="MKKSVTLLSIGLASLLLAACAPHKSQKSSWDTIKEKGVLKVATPG
                     TYQPTSFYNDNNELVGYEVDMVKEIGKRLNIKVKFVETGFDQAFTSVDSGRVDISLNNF
                     DITPKRQKKYNISTPYKYGVGGMIVRADGSSNMAKKDLSDWKGKKAAGASGTEYMKVAQ
                     KQGAELVTYDNVTGDVYLNDVANGRTDFIPNDYPAQKLFVDYMLSQNPNLNVKMSDVQY
                     NPTEQGIVMNKKDDSLKKKIDAVIKDMIKDGSLKKISETYYAGQDLTKPFGKDKKIPVI
                     DTKDVN"
     gene            complement(2362..3816)
                     /locus_tag="ETT59_RS05405"
                     /old_locus_tag="ETT59_05405"
     CDS             complement(2362..3816)
                     /EC_number="3.5.1.4"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1105: amidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407508.1"
                     /locus_tag="ETT59_RS05405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT59_05405"
                     /product="amidase"
                     /protein_id="WP_136075274.1"
                     /transl_table=11
                     /translation="MTYQDATAMAIAVQTGQTTPLELVTQAIYKAKKLNPTLNAITSER
                     FEAALEEAKQRDFSGLPFAGVPIFLKDLGQELKGHSSTSGSRLFKEYQATKTDLFVKRL
                     EALGFIILGRSNTPEFGFKNISDSSLHGPVNLPKDNTRNAGGSSGGAAALVSSGISALA
                     TASDGGGSIRIPASFNGLIGLKPSRGRMPVGPGSYRSWQGASVHFALTKSVRDTRNLLY
                     YLQMEQMESPFPLATLTKDSIYQSLQRPLTIAFYQRLSDGSPVSLDTAKALRQAVTWLR
                     EQGHQLVELEEFPVNMTEVIRHYYIMNSVETAAMFADIEDTFGRPMTKDDMETMTWAIY
                     QSGKDIPAWRYSLVLQKWDTYSATMASFHETYDLLLTFTTNTPAPKHGELVPDSKLMAN
                     LAQAEIFSSEEQFNLVETMFGKSLAINPYTALPNLTGQPAISLPTYETKEGLPMGIQLI
                     AAKGREDLLLGIAEQFEAAGLLKIPQ"
     gene            complement(4013..4642)
                     /gene="pyrE"
                     /locus_tag="ETT59_RS05410"
                     /old_locus_tag="ETT59_05410"
     CDS             complement(4013..4642)
                     /EC_number="2.4.2.10"
                     /GO_function="GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pyrE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922180.1"
                     /locus_tag="ETT59_RS05410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT59_05410"
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="WP_002990137.1"
                     /transl_table=11
                     /translation="MTLASQIATQLLDIKAVYLKPEDPFTWASGIKSPIYTDNRVTLSY
                     PKTRDLIENGFVETIRAHFPEVEVIAGTATAGIPHGAIIADKMTLPFVYIRSKPKDHGA
                     GNQIEGRVLKGQKMVIIEDLISTGGSVLDAAAAASREGADVLGVVAIFTYELPKASQNF
                     KEAGIKLITLSNYTELIAVAKLQGYITNDGLHLLKKFKEDQVNWQQ"
     gene            complement(4700..5392)
                     /gene="pyrF"
                     /locus_tag="ETT59_RS05415"
                     /old_locus_tag="ETT59_05415"
     CDS             complement(4700..5392)
                     /EC_number="4.1.1.23"
                     /GO_function="GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA]"
                     /GO_process="GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="pyrF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984921.1"
                     /locus_tag="ETT59_RS05415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT59_05415"
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="WP_012560625.1"
                     /transl_table=11
                     /translation="MKEERPIIALDFSSFEETKAFLDLFPAEEKLYVKIGMELYYAQGP
                     DIVRYIKSLGHNVFLDLKLHDIPNTVRAAMAVLKELDIDMATVHAAGGVEMLKAAREGL
                     GQGPTLIAVTQLTSTSEDQMRGDQNIQTSLLESVLHYSKGAAKAQLDGVVCSAQEVEAI
                     KAVTPTGFNCLTPGIRPKGSNIGDQKRVMTPNQARRIGSDYIVVGRPITQAKDPVATYQ
                     AIKAEWAG"
     gene            complement(5669..6205)
                     /locus_tag="ETT59_RS05420"
                     /old_locus_tag="ETT59_05420"
     CDS             complement(5669..6205)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990141.1"
                     /locus_tag="ETT59_RS05420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT59_05420"
                     /product="hypothetical protein"
                     /protein_id="WP_002984923.1"
                     /transl_table=11
                     /translation="MNVTEQNSHQILIQKLLVSIHYLTLFRDELKLVERTPSILGGEFP
                     AHLVQSELGDIVAAIDTLDMQQRLIESTFWYEESAFKLMNKTLDIVDNWIKGVDHLIDL
                     CQSKEVFQIIIGDKRIRVFGVLSDVFSSLKVSALSLKEAPIPDVLYEHIQRVNLEEEAF
                     IKYYQSPKVPTGEFE"
     gene            6427..7332
                     /locus_tag="ETT59_RS05425"
                     /old_locus_tag="ETT59_05425"
     CDS             6427..7332
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284709.1"
                     /locus_tag="ETT59_RS05425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT59_05425"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_136276351.1"
                     /transl_table=11
                     /translation="MRIQQLHYIIKIVECGSMNEAAKQLFITQPSLSNAVKDLEMEMGI
                     TIFNRNPKGITLTKDGVEFLSYARQIIEQTSLLEDRYKNHNTGRELFSVSSQHYAFVVN
                     AFVSLLKRTDMTRYELFLRETRTWEIIDDVKNFRSEIGVLFINDYNRDVLTKLFDDNHL
                     TASPLFKAQPHIFVSKSNPLATKSLLSMDDLRNFPYLSYDQGIHNSFYFSEEMMSQMPH
                     NKSIVVSDRATLFNLMIGLDGYTVASGILNSNLNGDQIVAIPLDVPDEIDIVFIKHEKA
                     NLSKMGERFIEYLLEEVTFD"
     gene            complement(7412..8200)
                     /locus_tag="ETT59_RS05430"
                     /old_locus_tag="ETT59_05430"
     CDS             complement(7412..8200)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984926.1"
                     /locus_tag="ETT59_RS05430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT59_05430"
                     /product="LytR family transcriptional regulator"
                     /protein_id="WP_136075720.1"
                     /transl_table=11
                     /translation="MTNNQTLDILLDVYAYNHAFRIAKALPNIPKTALYLLEMLKERRE
                     LNLAFLAEHAAENRTIEDQYHCSLWLNQSLEDEQIANYILDLEVKVKNGAIIDFVRSVS
                     PILYRLFLRLITSEIPNFKAYIFDTKNDQYDTWHFQAMLESDHEVFKAYLSQKQSRNVT
                     TKSLADMLTLTSLPQEIKDLVFLLRHFEKAVRNPLAHLIKPFDEEELYRTTHFSSQAFL
                     ENIITLATFSGVIYRCEPFYFDDMNAIIKKELSLWRQSIV"
     gene            complement(8193..8906)
                     /gene="deoD"
                     /locus_tag="ETT59_RS05435"
                     /old_locus_tag="ETT59_05435"
     CDS             complement(8193..8906)
                     /EC_number="2.4.2.1"
                     /GO_function="GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene="deoD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984928.1"
                     /locus_tag="ETT59_RS05435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT59_05435"
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="WP_002990147.1"
                     /transl_table=11
                     /translation="MSIHISAKKGDIADKILLPGDPLRAKFIAENFLEDAVCFNEVRNM
                     FGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKTLIRVGTAGAIDPEVHVRELV
                     LAQAAATNSNIIRNDFPEFDFPQIADFGLLDKAYHIAREMGVTTHVGNVLSSDVFYTNM
                     PERNMALGKLGVKAIEMEAAALYYLAAQHHVKALGIMTISDNLNDPTEDTTAEERQTTF
                     TDMMKVGLETLIAND"
     misc_feature    9359..9372
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.2"
                     /tool="antismash"
     gene            complement(9572..10381)
                     /locus_tag="ETT59_RS05440"
                     /old_locus_tag="ETT59_05440"
     CDS             complement(9572..10381)
                     /EC_number="2.4.2.1"
                     /GO_function="GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647060.1"
                     /locus_tag="ETT59_RS05440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT59_05440"
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="WP_053308308.1"
                     /transl_table=11
                     /translation="MSLMTKINETKDFLVTKGIETPEFGLILGSGLGELAEEVENAIVI
                     DYADIPNWGKSTVVGHAGKLVYGDLAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKALG
                     CEGVLVTNAAGGIGYGPGTLMAITDHINMTGNNPLIGENLDEFGPRFPDMSDAYTKVYR
                     NKAHEVAEKMNIKLEDGVYMGLTGPTYETPAEIRAFKVLGADAVGMSTVPEVIVAAHSG
                     LKVLGISAITNFAAGFQSELNHEEVVEVTEHIKEDFKGLVKAILAEL"
     gene            complement(10365..10805)
                     /gene="arsC"
                     /locus_tag="ETT59_RS05445"
                     /old_locus_tag="ETT59_05445"
     CDS             complement(10365..10805)
                     /EC_number="1.20.4.1"
                     /GO_function="GO:0008794 - arsenate reductase
                     (glutaredoxin) activity [Evidence IEA]"
                     /GO_process="GO:0046685 - response to arsenic-containing
                     substance [Evidence IEA]"
                     /codon_start=1
                     /gene="arsC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922177.1"
                     /locus_tag="ETT59_RS05445"
                     /note="This arsenate reductase requires both glutathione
                     and glutaredoxin to convert arsenate to arsenite, after
                     which the efflux transporter formed by ArsA and ArsB can
                     extrude the arsenite from the cell, providing resistance.;
                     This arsenate reductase requires both glutathione and
                     glutaredoxin to convert arsenate to arsenite, after which
                     the efflux transporter formed by ArsA and ArsB can extrude
                     the arsenite from the cell, providing resistance; Derived
                     by automated computational analysis using gene prediction
                     method: Protein Homology."
                     /old_locus_tag="ETT59_05445"
                     /product="arsenate reductase (glutaredoxin)"
                     /protein_id="WP_053308307.1"
                     /transl_table=11
                     /translation="MEEITIYHNPNCGTSRNVLAMIRHAGIEPTIIEYLQTPPNRETLI
                     ELLQSMAISAQELLRTNVPEFEAHGLANQAVAEKDVINAMLTDPILINRPIVVTRKGVK
                     LCRPSETLLDILPVPLPSPYMKEDGESVNPIEVKGEKDVIDD"
     gene            complement(10821..12032)
                     /locus_tag="ETT59_RS05450"
                     /old_locus_tag="ETT59_05450"
     CDS             complement(10821..12032)
                     /EC_number="5.4.2.7"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008973 - phosphopentomutase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009117 - nucleotide metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184417.1"
                     /locus_tag="ETT59_RS05450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT59_05450"
                     /product="phosphopentomutase"
                     /protein_id="WP_002990153.1"
                     /transl_table=11
                     /translation="MSKFNRIHLVVLDSVGIGAAPDADKFFNAGVADTDSDTLGHISET
                     AGLSVPNMAKIGLGNISRPIPLKTIPTEDNPTGYVTKLEEVSLGKDTMTGHWEIMGLNI
                     TEPFDTFWNGFPEEILTKIEEFSGRKIIREANKPYSGTAVIDDFGPRQMETGELIVYTS
                     ADPVLQIAAHEDIIPVEELYKICEYARSITLERPALLGRIIARPYVGEPGNFTRTANRH
                     DYAVSPFQDTVLNKLADAGVPTYAVGKINDIFNGSGITNDMGHNKSNSHGIDTLIKTLQ
                     LPEFTKGFSFTNLVDFDANFGHRRDPEGYRDCLHEFDNRLPEIFANMKEDDLLLITADH
                     GNDPTYAGTDHTREYIPLLAYSASFTGNGLIPQGHFADISATVAENFGVDTAMIGESFL
                     GHLK"
     gene            complement(12109..12792)
                     /gene="rpiA"
                     /locus_tag="ETT59_RS05455"
                     /old_locus_tag="ETT59_05455"
     CDS             complement(12109..12792)
                     /EC_number="5.3.1.6"
                     /GO_function="GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /gene="rpiA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881270.1"
                     /locus_tag="ETT59_RS05455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT59_05455"
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="WP_009881270.1"
                     /transl_table=11
                     /translation="MEALKKIAGVTAAQYVTDGMTIGLGTGSTAYYFVEEIGRRVKQEG
                     LQVVGVTTSSVTSKQAEGLGIPLKSIDDIDSIDLTVDGADEVDKDFNGIKGGGAALLME
                     KIVATPTKEYIWVVDASKMVEHLGAFKLPVEVVQYGADRLFRVFEKAGYKPSFRMKGDS
                     RLVTDMQNYIIDLDLGCIKDPVAFGHLLDGTVGVVEHGLFNGMVDKVIVASKDGVTVLE
                     APKAG"
     misc_feature    complement(13026..13039)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 22.77"
                     /tool="antismash"
     gene            13170..15269
                     /locus_tag="ETT59_RS05460"
                     /old_locus_tag="ETT59_05460"
     CDS             13170..15269
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1223: ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922175.1"
                     /locus_tag="ETT59_RS05460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT59_05460"
                     /product="AAA family ATPase"
                     /protein_id="WP_136276350.1"
                     /transl_table=11
                     /translation="MTHFSGKDPFVNMDDIFNQLMANMGGYRSENPRYLVNGREITPEE
                     FQHYRQTGQLPVATTKATNSQMLTPKADSVLTQLGTNLTQEARQGHLDPVIGRNKEIQD
                     TAEILARRTKNNPVLVGDAGVGKTAVIEGLAQAIVNGGVPAAIKNKEIVSIDISSLEAG
                     TQYRGSFEETIQNLIQEVKEAGNIILFFDEIHQIVGAGATSSDSGSKGLADILKPALSR
                     GELTLIGATTQDEYRNTILKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQHHHIT
                     LPDNVLKAAVDYSIQYIPQRSLPDKAIDLLDMTAAHLAAQHPVTDLKTLETEIAKQKES
                     QEKAVAKEDFEKALAAKTRIETLQKQIEQHNQSQNVTATVNDIAESVERLTGIPVSNMG
                     TNDLERLKGISSRLKSHVIGQDEAVAAVARAIRRNRAGFDDGNRPIGSFLFVGPTGVGK
                     TELAKQLALDLFGSKDAIIRLDMSEYNDRTAVSKLIGTTAGYVGYDDNNNTLTERVRRN
                     PYAIVLLDEIEKADPQIITLLLQVLDDGRLTDGQGNTINFKNTVIIATSNAGFGQQDTE
                     TSESNIMDRIAPYFRPEFLNRFNSIIKFNHLQKENLEEIVDLMLAEVNQTTAKKGISLT
                     IADDAKAHLIDLGYNHAMGARPLRRIIEQEIRDRITDYYLDHPEVKKLQAILKEGQLVI
                     RQKDQ"
     gene            complement(15327..16070)
                     /locus_tag="ETT59_RS05465"
                     /old_locus_tag="ETT59_05465"
     CDS             complement(15327..16070)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984942.1"
                     /locus_tag="ETT59_RS05465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT59_05465"
                     /product="hypothetical protein"
                     /protein_id="WP_002984942.1"
                     /transl_table=11
                     /translation="MTQVAQGRSKGKSLLCHQCNALFVFIIFLILLAVLFGVRYRNSSI
                     EGIWRTTSIDQKLGDDFAKRLTGLHQSPLIDDSLLTSSQMILTVKNNNVDLSFSVQVER
                     DIFVKRLAAYHQNELLKTLKENHLVVGDLSSKERQIIENSMPASHELEMILDQAFEKLA
                     SQIGGKYNQKTGHLSAVVLKGKVNRILHTIDIKEEVAAGHTSFSKGLLTPNGYFDYTRF
                     GKKLELLGDEKIIFKKALKKSPSSV"
     gene            complement(16218..16817)
                     /gene="yihA"
                     /locus_tag="ETT59_RS05470"
                     /old_locus_tag="ETT59_05470"
     CDS             complement(16218..16817)
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0043022 - ribosome binding [Evidence IEA]"
                     /GO_process="GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="yihA"
                     /gene_functions="other (smcogs) SMCOG1227: ribosome
                     biogenesis GTP-binding protein YsxC"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054379.1"
                     /locus_tag="ETT59_RS05470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT59_05470"
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="WP_053308304.1"
                     /transl_table=11
                     /translation="MAEEQVLNTHNASILLSAANKSHYPQDDLPEIALAGRSNVGKSSF
                     INTILGRKNLARTSSKPGKTQLLNFFDIDDKLRFVDVPGYGYAKVSKSERAKWGKMIEE
                     YLTTRDNLRAVVSLVDLRHAPSKEDIQMYDFLKYYDIPVIVVATKADKIPRGKWNKHES
                     VVKKALNFDKSDTFIVFSSVERIGIDDSWDAILEQV"
     gene            complement(16827..18056)
                     /gene="clpX"
                     /locus_tag="ETT59_RS05475"
                     /old_locus_tag="ETT59_05475"
     CDS             complement(16827..18056)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="clpX"
                     /gene_functions="other (smcogs) SMCOG1223: ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984948.1"
                     /locus_tag="ETT59_RS05475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT59_05475"
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="WP_002984948.1"
                     /transl_table=11
                     /translation="MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEI
                     IKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDRAKRALSVAVYNHYKRVSFTESRDD
                     DDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENILLK
                     LIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVP
                     PQGGRKHPNQEMIQIDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASY
                     MQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIQILTEPRNALVKQYQALLSYDG
                     VELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVE
                     GKSKPVLETA"
     gene            complement(18186..18356)
                     /locus_tag="ETT59_RS05480"
                     /old_locus_tag="ETT59_05480"
     CDS             complement(18186..18356)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302775.1"
                     /locus_tag="ETT59_RS05480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT59_05480"
                     /product="hypothetical protein"
                     /protein_id="WP_002990165.1"
                     /transl_table=11
                     /translation="MQRSIFGVFTAFLCVICVLCAIPAFKKNRYGLGSLFLLNAFTNLV
                     NSIHAFYGTLF"
     gene            complement(18376..18873)
                     /locus_tag="ETT59_RS05485"
                     /old_locus_tag="ETT59_05485"
     CDS             complement(18376..18873)
                     /EC_number="1.5.1.3"
                     /GO_function="GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005542 - folic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984955.1"
                     /locus_tag="ETT59_RS05485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT59_05485"
                     /product="dihydrofolate reductase"
                     /protein_id="WP_053308303.1"
                     /transl_table=11
                     /translation="MTKEIIAIWAEDEAGLIGVAGKLPWYLPKELEHFKKTTLHQAILM
                     GRVTFEGMNCKRLPQRQTLVMTRNRDYQVDEVLTMTSIEKVLEWYHAQDKTLYIIGGNK
                     VLEAFNGYFDRIIKTVIHHRFKGDTYRPNLDFSHFTQERQTFYARDAKNPYDFTVTALK
                     HK"
     gene            complement(18953..19792)
                     /locus_tag="ETT59_RS05490"
                     /old_locus_tag="ETT59_05490"
     CDS             complement(18953..19792)
                     /EC_number="2.1.1.45"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /locus_tag="ETT59_RS05490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT59_05490"
                     /product="thymidylate synthase"
                     /protein_id="WP_011017679.1"
                     /transl_table=11
                     /translation="MTKADQIFKANIQKIINEGSLSEQARPKYKDGRTAHSKYITGAFA
                     EYDLAKGEFPITTLRPIPIKSAIKELFWIYQDQSNSLDVLEAKYNVHYWNEWEVDQTRT
                     IGQRYGAVVKKHDIISKILKQLAENPWNRRNVISLWDYEAFEETKGLLPCAFQIMFDVR
                     RVGEDLYLDASLTQRSNDILVAHHINAMQYVALQMMIAKHFGWKIGKFFYFVNNLHIYD
                     NQFDQAQELLKRQPVASQPKLVLNVPDGTNFFDIKPDDFELQNYDPVKPQLHFDLAI"
     misc_feature    complement(19748..19762)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 23.77"
                     /tool="antismash"
     gene            20001..21176
                     /locus_tag="ETT59_RS05495"
                     /old_locus_tag="ETT59_05495"
     CDS             20001..21176
                     /EC_number="2.3.3.10"
                     /GO_function="GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043: hydroxymethylglutaryl-CoA synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993959.1"
                     /locus_tag="ETT59_RS05495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT59_05495"
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="WP_032464957.1"
                     /sec_met_domain="Chal_sti_synt_N (E-value: 4.3e-07,
                     bitscore: 26.2, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIGIDKIGFATSQYVLKLEDLALARQVDPAKFSQGLLIESFSVA
                     PITEDIITLAASAADQILTDEDRSKIDMVILATESSTDQSKASAIYVHHLVGIQPFARS
                     FEVKQACYSATAALDYAKLHVASKPDSRVLVIASDIARYGVGSPGESTQGSGSIALLVT
                     ANPRILALNKDNVAQTRDIMDFWRPNYSFTPYVDGIYSTKQYLNCLETTWQAYQKRENL
                     QLSDFAAVCFHIPFPKLALKGLNNIMDNTVPPEHREKLTEAFQASITYSKQIGNIYTGS
                     LYLGLLSLLENSKVLQSGDKIGFFSYGSGAVSEFYSGQLVAGYDKMLMTNRQALLDQRT
                     RLSVSKYEDLFYEQVQLDDNGNANFDIYLTGKFALTAIKEHQRIYHTNDKN"
     gene            21163..22440
                     /locus_tag="ETT59_RS05500"
                     /old_locus_tag="ETT59_05500"
     CDS             21163..22440
                     /EC_number="1.1.1.88"
                     /GO_function="GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA]"
                     /GO_function="GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1187: hydroxymethylglutaryl-CoA reductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880299.1"
                     /locus_tag="ETT59_RS05500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT59_05500"
                     /product="hydroxymethylglutaryl-CoA reductase, degradative"
                     /protein_id="WP_010922170.1"
                     /transl_table=11
                     /translation="MTKTNLNWSGFSKKTFEERLQLIEKFKLLNAENLNQLKTDVLLPI
                     QTANQMTENVLGRLALPFSIAPDFLVNGSTYQMPFVTEEPSVVAAASFAAKLIKRSGGF
                     KAQTLNRQMIGQIVLYDIDQIDNAKAAILHKTKKLIALANKAYPSIVKRGGGARTIHLE
                     EKGEFLIFYLTVDTQEAMGANMVNTMMEALVPDLTRLSKGHCLMAILSNYATESLVTTS
                     CEIPVRLLDHDKTKSLQLAQKIELASRLAQVDPYRATTHNKGIFNGIDAVVIATGNDWR
                     AIEAGAHAYASRNGSYQGLSQWHFDQDKQVLLGQMTLPMPIASKGGSIGLNPTVSIAHD
                     LLNQPDAKTLAQLIASVGLAQNFAALKALTSSGIQAGHMKLHAKSLALLAGATQDEIAP
                     LVNALLADKPINLEKAHFYLSQLRQS"
     gene            complement(22670..23659)
                     /gene="fni"
                     /locus_tag="ETT59_RS05505"
                     /old_locus_tag="ETT59_05505"
     CDS             complement(22670..23659)
                     /EC_number="5.3.3.2"
                     /GO_function="GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="fni"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984966.1"
                     /locus_tag="ETT59_RS05505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT59_05505"
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="WP_010922169.1"
                     /transl_table=11
                     /translation="MTNRKDDHIKYALKYQSPYNAFDDIELIHHSLPSYDLSDIDLSTH
                     FAGQDFDFPFYINAMTGGSQKGKAVNEKLAKVAAATGIVMVTGSYSAALKNPNDDSYRL
                     HEVADNLKLATNIGLDKPVALGQQTVQEMQPLFLQVHVNVMQELLMPEGERVFHTWKKH
                     LAEYASQIPVPVILKEVGFGMDVNSIKLAHDLGIQTFDISGRGGTSFAYIENQRGGDRS
                     YLNDWGQTTVQCLLNAQGLMDQVEILASGGVRHPLDMIKCFVLGARAVGLSRTVLELVE
                     KYPTERVIAIVNGWKEELKIIMCALDCKTIKELKGVDYLLYGRLQQVN"
     gene            complement(23646..24659)
                     /locus_tag="ETT59_RS05510"
                     /old_locus_tag="ETT59_05510"
     CDS             complement(23646..24659)
                     /EC_number="2.7.4.2"
                     /GO_function="GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016126 - sterol biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635411.1"
                     /locus_tag="ETT59_RS05510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT59_05510"
                     /product="phosphomevalonate kinase"
                     /protein_id="WP_136046441.1"
                     /transl_table=11
                     /translation="MSNYCVQTGGKLYLTGEYAILTPGQKALIHFIPLMMTAEISPAAH
                     IQLASDMFAHKAGMTPDASYALIQATVKTFADYLGQSIDQLEPFSLIIMGKMERDGKKF
                     GIGSSGSVTLLTLKALSAYYQITLTPELLFKLAAYTLLKQGDNGSMGDIACIAYQTLVA
                     YTSFDREQVSNWLQTMPLKKLLVKDWGYHIQVIQPALPCDFLVGWTKIPAISRQMIQQV
                     TASITPAFLRTSYQLTQSAMVALQEGHKEELKKSLAGASHLLKELHSAIYHPKLVTLVA
                     ACQKQDAVAKSSGSGGGDCGIALAFNQNARDTLISKWQEADIALLYQERWGENDQP"
     gene            complement(24652..25596)
                     /gene="mvaD"
                     /locus_tag="ETT59_RS05515"
                     /old_locus_tag="ETT59_05515"
     CDS             complement(24652..25596)
                     /EC_number="4.1.1.33"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA]"
                     /GO_process="GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /gene="mvaD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888980.1"
                     /locus_tag="ETT59_RS05515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT59_05515"
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="WP_011284696.1"
                     /transl_table=11
                     /translation="MDPNVITVTSYANIAIIKYWGKENQAKMIPSTSSISLTLENMFTT
                     TSVSFLPDTATSDQFYINGVLQNDEEHTKISTIIDQFRQPGQAFVKMETQNNMPTAAGL
                     SSSSSGLSALVKACDQLFDTQLDQKALAQKAKFASGSSSRSFFGPVAAWDKDSGAIYKV
                     ETDLKMAMIMLVLNAAKKPISSREGMKLCRDTSTTFDEWVEQSAIDYQHMLTYLKTNNF
                     EKVGQLTEANALAMHATTKTANPPFSYLTKESYQAMEAVKELRQEGFACYFTMDAGPNV
                     KVLCLEKDLAQLAERLGKNYRIIVSKTKDLPDV"
     gene            complement(25578..26456)
                     /gene="mvk"
                     /locus_tag="ETT59_RS05520"
                     /old_locus_tag="ETT59_05520"
     CDS             complement(25578..26456)
                     /EC_number="2.7.1.36"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004496 - mevalonate kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016126 - sterol biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /gene="mvk"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054375.1"
                     /locus_tag="ETT59_RS05520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT59_05520"
                     /product="mevalonate kinase"
                     /protein_id="WP_011284695.1"
                     /transl_table=11
                     /translation="MNENIGYGKAHSKIILIGEHAVVYGYPAIALPLTDIEVVCHIFPA
                     DKPLVFDFYDTLSTAIYAALDYLQRLQEPIAYEIVSQVPQKRGMGSSAAVSIAAIRAVF
                     SYCQEPLSDDLLEILVNKAEIIAHTNPSGLDAKTCLSDHAIKFIRNIGFETIEIALNGY
                     LVIADTGIHGHTREAVNKVAQFEETNLPYLAKLGALTQALERAINQKNKVAIGQLMTQA
                     HSALKAIGVSISKADQLVEAALRAGALGAKMTGGGLGGCMIALADTKDMAEKISHRLKE
                     EGAVNTWIQML"
     gene            complement(26749..27981)
                     /locus_tag="ETT59_RS05525"
                     /old_locus_tag="ETT59_05525"
     CDS             complement(26749..27981)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888981.1"
                     /locus_tag="ETT59_RS05525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT59_05525"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_053308301.1"
                     /transl_table=11
                     /translation="MFNRIRIRFIMIASIAIFIILSSIVGIINTARCYQSQQEINRILH
                     LISSNKGKLPGTTESSKRLGTKLSEDSLSQFRYYSVIFNANGHLLSSNTANISALDREE
                     AQYFARLFAKSGEEKGSYRHQDSVYSYLITQLPNEEKLVVILDTTFYFRSVGDLLAVSM
                     MLAFGGFIFFVVLVSLFSGMVIKPFVQNYEKQRRFITNAGHELKTPLAIISANNELVEL
                     MTGESEWTKSTSDQVKRLTGLINQMITLARLEEQPDVVLHMVDFSVIAQDAAEDFKSLV
                     LKDGKRFDLTIQPNIMIKAEEKSLFELVTILVDNANKYCDPKGLVKVSLTTIGRRRKRA
                     KLEVSNTYLEGKSIDYSRFFERFYREDESHNSKEKGYGIGLSMAESMVKLFKGTITVNY
                     KNDAIVFTVVI"
     gene            complement(27990..28658)
                     /locus_tag="ETT59_RS05530"
                     /old_locus_tag="ETT59_05530"
     CDS             complement(27990..28658)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984985.1"
                     /locus_tag="ETT59_RS05530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT59_05530"
                     /product="response regulator transcription factor"
                     /protein_id="WP_002984985.1"
                     /transl_table=11
                     /translation="MKILLAEDEWQMSNVLTTAMTHQGYDVDVVFNGQEAIDKAKDNAY
                     DIMILDIMMPIKSGIEALKEIRASGNCSHIIMLTAMAEINDRVTGLDAGADDYLTKPFS
                     LKELLARLRSMERRVESFTPQVLQFAGVTLNINEQELSAGNAIRLASKEGKLMAFLMLN
                     QGKYLDTKTLYQHVWSDQEDYDTSIVWVYISYLRQKLLAIQANVIIAGDKDTSYCLLEK
                     "
     gene            complement(28661..29311)
                     /locus_tag="ETT59_RS05535"
                     /old_locus_tag="ETT59_05535"
     CDS             complement(28661..29311)
                     /GO_process="GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984988.1"
                     /locus_tag="ETT59_RS05535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT59_05535"
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="WP_053308300.1"
                     /transl_table=11
                     /translation="MKERLEHYSTSSIYSGFEVYLPLVLQTITDVIIAENIKSKKETGF
                     KLYEHFTSRIKSEASMIEKCQRKQLPLTSKSALKIIKDSIGIRIICGFIDDIYRMVDLL
                     KSIPGMSVNTEKDYILNAKPNGYRSYHLILELETHFPDILGEKKGCYFIEVQLRTIAQD
                     SWASLEHQMKYKHQVANAEMITRELKRCADELASCDVTMQTIRQLIQETTGEE"
     misc_feature    29447..29460
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.6"
                     /tool="antismash"
     misc_feature    29526..29539
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.3"
                     /tool="antismash"
     misc_feature    complement(29527..29540)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.93"
                     /tool="antismash"
     gene            29531..31543
                     /locus_tag="ETT59_RS05540"
                     /old_locus_tag="ETT59_05540"
     CDS             29531..31543
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1283: 2`,3`-cyclic-nucleotide 2`-phosphodiesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888982.1"
                     /locus_tag="ETT59_RS05540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT59_05540"
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="WP_136305945.1"
                     /transl_table=11
                     /translation="MKKYFILKSSVLSILTSFTLLVTDVQADQVDVQFLGVNDFHGALD
                     NTGTAYTPSGKIPNAGTAAQLGAYMDDAEIDFKQANQDGTSIRVQAGDMVGASPANSAL
                     LQDEPTVKVFNKMKFEYGTLGNHEFDEGLDEFNRIMTGQAPDPESTINDITKQYEHEAS
                     HQTIVIANVIDKKTNDIPYGWKPYAIKDIAINDKIVKIGFIGVVTTEIPNLVLKQNYEH
                     YQFLDVAETIAKYAKELQEQHVHAIVVLAHIPATSKDGVVDHEMATVMEKVNQIYPEHS
                     IDIIFAGHNHQYTNGTIGKTRIVQALSQGKAYADVRGTLDTDTNDFIKTPSANVVAVAP
                     GIKTENSDIKAIINHANDIVKTVTERKIGTATNSSTISKTENIDKESPVGNLVTTAQLT
                     IAKKTFPTVDFAMTNNGGIRSDLVVKNDRTITWGSAQAVQPFGNILQVIQMTGQHIYDV
                     LNQQYDENQTYFLQMSGLTYTYTDNDPKNSDTPFKIVKVYKDNGEEINLTTTYTVVVND
                     FLYGGGDGFSAFKKAKLVGAINTDTEAFITYITNLQASGKTVNATIKGVKNYVTSNLES
                     STKINSAGKHSIISKVFRNRDGNIVSSEVISDLLTSTENTNNSLGKKETTINKNTISSS
                     TLPITGDNYKMSPIMTILALISLGGLNAFIKKRKS"
     misc_feature    complement(29542..29555)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.33"
                     /tool="antismash"
     gene            complement(31625..32035)
                     /locus_tag="ETT59_RS05545"
                     /old_locus_tag="ETT59_05545"
     CDS             complement(31625..32035)
                     /EC_number="3.5.1.88"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017671.1"
                     /locus_tag="ETT59_RS05545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT59_05545"
                     /product="peptide deformylase"
                     /protein_id="WP_002984994.1"
                     /transl_table=11
                     /translation="MIREIITDHFLLQQKAQVAKKEDLWIGQDLQDTLAFYRQECLGMA
                     ANMIGEQKRIVIVSMGFIDLVMFNPVMVSKKGIYQTKESCLSLSGYRKTQRYDKITVEY
                     LDHNWRPKRLSLTGLTAQICQHELDHLEGILI"
     gene            complement(32291..32509)
                     /locus_tag="ETT59_RS09165"
                     /old_locus_tag="ETT59_05550"
     CDS             complement(32291..32509)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995561.1"
                     /locus_tag="ETT59_RS09165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT59_05550"
                     /product="hypothetical protein"
                     /protein_id="WP_014407501.1"
                     /transl_table=11
                     /translation="MALLFYYYVRKNQVKKLSQLKNLTEIFRKFIILTINNISAIKVFQ
                     TAGVLFGPVKVANARESSIWFENLTKQ"
     gene            <32752..>32829
                     /locus_tag="ETT59_RS09335"
                     /pseudo=""
     CDS             32752..>32829
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /locus_tag="ETT59_RS09335"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS3 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MDYCNNKRIKIKRKGLSPLQHRTKSF"
     gene            complement(32927..34804)
                     /locus_tag="ETT59_RS05555"
                     /old_locus_tag="ETT59_05555"
     CDS             complement(32927..34804)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922163.1"
                     /locus_tag="ETT59_RS05555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT59_05555"
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="WP_136305944.1"
                     /transl_table=11
                     /translation="MSHFLVEKLTKTVGDKTVFQDISFIIHDFDRIGIIGVNGTGKTTL
                     LDVLSGRLGFDGDHSPFSKANDYKIAYLTQDPEFNDASSVLDTVLSSDVKAIQLIRQYE
                     LLMANYTEDKQETLESLMSEMDRLDAWSIESDVKTVLSKLGITDLEQKVGDLSGGMRRR
                     VQLAQVLLGAADLLLLDEPTNHLDIDIIAWLTTYLKTAKKTVLFITHDRYFLDHVATRI
                     FELDKAGLTEYQGNYQDYVRLKAEQDERDATNLHKKKQLYKQELAWMRTQPQARATKQQ
                     ARINRFTDLKKEVHQDSSADKLEMAFETSRIGKKVIHFEDLSFAYGDRQLIKDFNLIIQ
                     NKDRIGIVGDNGVGKSTLLNLINGDLEPTSGKLDIGDTIRVGYFSQQLKDMDETKRVIN
                     YLQEVADEVKTSVGTTSISELLEQFLFPRSSHGTLIAKLSGGEKKRLYLLKLLIEKPNV
                     LLLDEPTNDLDIATLTVLENFLANFAGPVITVSHDRYFLDKVATKILAFEEGDIRVFYG
                     NYSDYLDEKVFEKETVEADLVKTTVTEEVPLPQKEERKRMSYLEKQEWAQIEDKIATIE
                     ANIEEIENQMLTVVSDYDQLAQLQKELDQHNNDLLLAYERFEYLSGLDI"
     gene            complement(34801..36009)
                     /locus_tag="ETT59_RS05560"
                     /old_locus_tag="ETT59_05560"
     CDS             complement(34801..36009)
                     /EC_number="2.7.7.72"
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880307.1"
                     /locus_tag="ETT59_RS05560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT59_05560"
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="WP_002990193.1"
                     /transl_table=11
                     /translation="MKLMTMPSEFQKALPILTKIKEAGYEAYFVGGSVRDVLLERPIHD
                     VDIATSSYPEETKAIFNRTVDVGIEHGTVLVLENGGEYEITTFRTEDVYVDYRRPSQVS
                     FVRSLEEDLKRRDFTVNALALDENGQVIDKFRGLIDLEQKRLRAVGKAEERFEEDALRI
                     MRGFRFAASLDFDIEAATFEAMRSHSPLLEKISVERSFTEFDKLLMAPHWRKGISAMIA
                     CQAYDYLPGLKQQEAGLNHLIVSLKDNFTFSDHHQAWAYVMISLAIEDPKSFLKAWKTS
                     NDFQRYVTKLIALYRIRQERSFEKLDIYQYGKEMASLVEGLRKAQSLSVDMDHIEALDQ
                     ALAIHNKYDIVLNGSHLIKDFGMKPGPQLGLMLEKVELAIVEGRLDNDFTTIEAFVREE
                     LAT"
     gene            complement(36134..36982)
                     /locus_tag="ETT59_RS05565"
                     /old_locus_tag="ETT59_05565"
     CDS             complement(36134..36982)
                     /GO_function="GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985007.1"
                     /locus_tag="ETT59_RS05565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT59_05565"
                     /product="DegV family protein"
                     /protein_id="WP_002990194.1"
                     /transl_table=11
                     /translation="MKLAVITDSTATLPTDLKQDKAIFSLDIPVIIDDETYFEGRNLSI
                     DDFYQKMADSQNLPKTSQPSLSELDNLLGLLSSKGYTHVIGLFLAGGISGFWQNIQFLA
                     EEHPEIEMAFPDSKITSAPLGSMVKNVLDWSRQGMTFQAILNKLQEQIDGTTAFIMVDD
                     LNHLVKGGRLSNGSALLGNLLSIKPILRFDEEGKIVVYEKVRTEKKAMKRLVEILNDLI
                     ADGQYNVSIIHSKAQDKADYLKRLLQDSGYQYDIEEVHFGAVIATHLGEGAIAFGVTPR
                     L"
     gene            complement(36982..37362)
                     /locus_tag="ETT59_RS05570"
                     /old_locus_tag="ETT59_05570"
     CDS             complement(36982..37362)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985011.1"
                     /locus_tag="ETT59_RS05570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT59_05570"
                     /product="DUF1149 family protein"
                     /protein_id="WP_002985011.1"
                     /transl_table=11
                     /translation="MQLVREKEFVNQYHYDARNLEWEKENGTPETNFEVTFQLIDKDEQ
                     QKETVIVSVLQFVIVKEEFVISGVISQMVRILDRLVDKPSEFTQEEVESLAAPLLDMVK
                     RLTYEVTEIALDRPGIHLEFKN"
     gene            complement(37590..37766)
                     /locus_tag="ETT59_RS05575"
                     /old_locus_tag="ETT59_05575"
     CDS             complement(37590..37766)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ETT59_RS05575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ETT59_05575"
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="WP_002985013.1"
                     /transl_table=11
                     /translation="MIKLYGFKYGLVGEVLRRIERLGFTFERLELRQASSKYLAKHDEA
                     LVINLFILDLKLT"
     misc_feature    complement(38189..38202)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.36"
                     /tool="antismash"
     misc_feature    38233..38246
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.62"
                     /tool="antismash"
     gene            38269..39294
                     /locus_tag="ETT59_RS05580"
                     /old_locus_tag="ETT59_05580"
     CDS             38269..39294
                     /EC_number="3.4.22.-"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635407.1"
                     /locus_tag="ETT59_RS05580"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases.; This family includes IgM or IgG-cleaving
                     cysteine proteases.; This family includes IgM or
                     IgG-cleaving cysteine proteases.; This family includes IgM
                     or IgG-cleaving cysteine proteases; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="ETT59_05580"
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="WP_053308297.1"
                     /transl_table=11
                     /translation="MRKRCYSTSAAVLAAVTLFALSVDRGVIADSFSANQEIIYSEVTP
                     YHVTSVWTKGVIPPANFTQGEDVFHAPYVANQGWYDITKTFNGKDDLLCGAATAGNMLH
                     WWFDQNNEKIEAYLKKHPDKQKIMFGDQELLDVRKVINTKGDQTNSELFNYFRDKAFPG
                     LSARRIGVMPDLVLDMFINGYYLNVYKTQTTDVNRTYQEKDRRGGIFDAVFTRGDQSKL
                     LTSRHDFKEKNLKEISDLIKKELTEGKALGLSHTYANVRINHVINLWGADFDSNGNLKA
                     IYVTDSDSNASIGMKKYFVGVNSSGKVAISAKEIKEDNIGAQVLGLFTLSTGQDSWNQT
                     N"
     gene            39407..39679
                     /locus_tag="ETT59_RS05585"
                     /old_locus_tag="ETT59_05585"
     CDS             39407..39679
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014875.5"
                     /locus_tag="ETT59_RS05585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT59_05585"
                     /product="exotoxin beta-grasp domain-containing protein"
                     /protein_id="WP_391592265.1"
                     /transl_table=11
                     /translation="MKIDKDIVTIQEFDFKIRKFLMESKEIHLTKSPYIRGSLEIHSKN
                     RKHEKIDLYDAKPNSTRSDVFKKYKDNKTINMKDFSHFDIYLWTK"
     gene            <39904..40194
                     /locus_tag="ETT59_RS05590"
                     /old_locus_tag="ETT59_05590"
                     /pseudo=""
     CDS             <39904..40194
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1026: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611514.1"
                     /locus_tag="ETT59_RS05590"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="ETT59_05590"
                     /product="IS3 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="SDQGWQYQHNYYHHFLNSKGIRPSMSRKRNSPNNSMMESFFGILK
                     SEMFYGYENNYKSLEDLEQAITNDIDYYNDKHIKVKLKGFSSVQYRTKSFT"
     gene            complement(40251..40958)
                     /locus_tag="ETT59_RS05595"
                     /old_locus_tag="ETT59_05595"
     CDS             complement(40251..40958)
                     /GO_function="GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990206.1"
                     /locus_tag="ETT59_RS05595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT59_05595"
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="WP_002990206.1"
                     /transl_table=11
                     /translation="MTKKKGKLVLISLFVLAACLGAYSAMRQSHKTSNVSAETIASSST
                     RHFIDEIGPTASTIGQERDLYASVMIAQAILESSNGKSSLSQAPYYNFFGIKGAYNGSS
                     VTMSTWEDDGNGNTYTIDQAFRAYPSIADSLNDYADLLSSSTYIGARKSNTLSYQDATA
                     ALTGLYATDTSYNLKLNNIIATYGLTAYDVANSSAQETGLATSGYVWNEYRRNYTDAET
                     LAVDEAWAKRMTY"
ORIGIN
        1 cgataagatg acaaagggct tggatgagag ctctcgatga tgtggtgctt tggattagta
       61 atgaaggctt ttttcttcct tgcataagct ccccacaaaa tgaaaactac agggctgtct
      121 ttctcattca gcactttaat aacagcgtct gtaaatggct cccatattaa gcctgcatgc
      181 ccattagcct gtcctgctgg cactgttaag caagcattca aaagcagaac cccttgacta
      241 gcccaagtgc ttaaatcatg atggtcacga ggaccaatgt catctgctaa ttcttttaaa
      301 atattaataa gggatggcgg agcagaaatc tcttctggaa ctgaaaatga taagccctgg
      361 gcctgtttgg ggccatgata agggtcttgt cctaaaatca acactttggt ttcttccaaa
      421 ggagtgactt gtaaggcttt aaagacattt tctcgtggag gatagacaag accggaagca
      481 taggcttcat ctaaaaagtg attgatgcga ccatagtaat gctccggcaa aaatgattta
      541 attttctcat gccaaattga atgagccata agattccttt ctaatcacgt cagtttctaa
      601 gttaaatacg atgtcctttt ctatctagtt taccacattt taaatagaaa gatcctgaaa
      661 atatgatatt tccagggtta atattcgttt tttacaggat attaaacaag tgctagctta
      721 ttttctaaga attcttggta acgttctaac aaaaaagcaa taagccaata gataaaggct
      781 actaaaatat acatggacat gtaatcccac tctctaccgc caataatttt ggcattttga
      841 aaaatatctg gtacggtaat catggcagct agcgacgaac ttttaaccat atcaataatg
      901 acatttccta aaggaggaac tgcaattcga aaagcttgag gaagaataat tttcttaacc
      961 ataagagcat atggcaaccc taaagcctta gctgcttccc attgtccctt atcaatagct
     1021 tctatagaag agcgaaaaac ttcagaaata taggcagcgc taaccataga aaaaccaaga
     1081 taagcgcaaa gtaaagctgg caattctaaa ccataataag gcaacccgaa ataaagaaca
     1141 aagagcacca cgatcatcgg cacacctcgc ataatagaga tgtacgctct gacaagataa
     1201 tgaatcaacg gctgacgtga ccttcccaga agggctaggc ctaaacctaa aaacagaccc
     1261 gtaaaaaaac tgagcaacga aataccaagg gtataaggta atcccgataa cacaaatcct
     1321 aaactatctt tcattaatgg gatattaatc atgtggttag gactccttta acatcaagta
     1381 ttagttaacg tctttcgtat caatgacggg aatttttttg tctttgccaa aaggttttgt
     1441 caaatcttga ccagcatagt aggtttcaga gattttcttc aagctaccat cttttatcat
     1501 gtctttaata acagcatcta tttttttctt gaggctatcg tcttttttgt tcataacaat
     1561 tccttgttcg gttgggttgt actgaacatc gctcattttg acatttagat ttggattttg
     1621 agataacatg taatccacaa ataatttttg agctgggtaa tcatttggaa tgaaatctgt
     1681 tcgaccgtta gccacatcgt ttagataaac atctcctgta acattatcgt aggtcaccag
     1741 ttcggctccc tgtttttgcg ctactttcat gtattctgtt ccagaagcgc cggctgcttt
     1801 ttttcctttc cagtcgctaa gatctttttt agccatgttt gagctgccat cagcacggac
     1861 aatcatgcct cctaccccgt atttataagg cgtagagata ttgtattttt tctgacgttt
     1921 tggggtaatg tcaaagttgt tcaaagaaat atccactcga ccactatcaa ctgaggtaaa
     1981 cgcttggtca aatcctgttt caacaaactt gactttaatg ttaagtcgtt taccgatttc
     2041 tttgaccata tctacttcgt aacctactaa ctcattatta tcgttgtaaa aagaagttgg
     2101 ctgataggtt cctggggtag ctacttttaa cacccctttt tctttgatag tgtcccaact
     2161 tgatttttga gatttatgtg gcgcacatgc tgccaataaa aggctggcaa gtccgataga
     2221 cagtaaagta actgatttct tcatagtaac tcctttatta agataagaat agtataacat
     2281 tttgattaag ttgtgttatc agtgagcgct caatctcttt aaaaagttaa tctataatag
     2341 ttaaactgtt ttataagatt attattgagg aatcttcaat aatcctgctg cctcaaactg
     2401 ttctgcaatt cctaataata ggtcctctct acctttggct gcaattagtt gaatgcccat
     2461 tgggagacct tccttagttt cgtaagtagg taaactaata gctggctggc cagttagatt
     2521 aggcagagct gtgtaaggat taatagccag actcttacca aacatggttt cgaccaaatt
     2581 gaattgctct tcactgctga aaatttcagc ttgagccaag ttagccatga gtttcgaatc
     2641 tgggacaagt tctccgtgct taggagctgg tgtgttggtt gtgaacgtca acaacaggtc
     2701 ataagtctca tgaaaactag ccatggttgc actgtacgta tcccattttt gaaggaccag
     2761 tgagtaacgc caagctggga tgtctttacc tgattggtaa atagcccagg tcatggtttc
     2821 catatcgtct ttggtcatcg gacgtccaaa agtgtcttca atatcagcaa acatagcagc
     2881 cgtttccaca ctattcataa tataataatg acgaatcact tctgtcatat ttacaggaaa
     2941 ctcttccaat tcaactagct gatgcccttg ttctcttagc caagttactg cttgtcttaa
     3001 agcttttgca gtatctaaag atactgggct accgtcactt aaccgttgat aaaaagcaat
     3061 tgtcaaggga cgttgtagcg attgataaat actatctttt gttaaggtgg ctagggggaa
     3121 ggggctttcc atttgttcca tctgtaaata gtagagtaga tttctagtat ctctaacgga
     3181 tttggtcaag gcaaaatgaa ctgaggctcc ttgccagctt cgataagaac caggtccgac
     3241 aggcatgcgc ccacggctag gtttgagccc aattaagccg ttaaacgagg ctggaatccg
     3301 aatagaacca ccaccatcac tagcagttgc tagcgcacta attcctgatg acactagagc
     3361 agcagctccc ccagatgagc caccagcatt tcgtgtatta tcctttggta aattcactgg
     3421 tccgtgcaaa ctgctatcgc taatattttt aaagccaaat tcaggcgtgt tggaacgccc
     3481 taaaataata aagcctaaag cttctaatct tttcacaaat aaatccgttt tagtcgcttg
     3541 atactcttta aacaatctgg aacctgaggt tgatgagtga ccttttaatt cttgtcccaa
     3601 atctttcaaa aaaatgggaa ctcctgcaaa aggcagacct gaaaaatccc tttgtttggc
     3661 ctcctctaga gctgcttcaa agcgttctga ggtaatagca tttaaggtag ggttcaactt
     3721 tttagcctta taaatagcct gggttactaa ttctagtggt gtggtctgac cagtctgaac
     3781 agcaatagcc atagccgtcg catcttgata agtcatagct actcttcctt tctaagatat
     3841 gaatcctaaa acattctttt ttattaaaac acaaataaaa gaaaaccacc attaaaaggt
     3901 tagaaattag aatgtgatgt gtaaggaatg tagacaaaac aatcaaaaca taacattttg
     3961 aattggggtt aaagagattt tttcattaaa aataaacctg gctgatagtt ccttattgtt
     4021 gccagtttac ctggtcttct ttaaattttt taagtaaatg taaaccatca ttagtaatat
     4081 agccttgcaa ctttgcaact gcaattagct cagtataatt agaaagcgta atcaacttga
     4141 taccagcttc tttaaaattc tgactagctt ttggtaactc ataagtgaaa atcgcaacaa
     4201 ctcccagaac gtcagctccc tcacgactgg ctgctgcggc tgcatctagt accgaaccac
     4261 ctgttgaaat caaatcttca atgataacca ttttttggcc tttaagcaca cgcccctcaa
     4321 tctggttgcc tgctccatga tcttttggct tactgcgaat ataaacaaaa ggaagagtca
     4381 ttttatctgc tataatggca ccgtgaggaa tacctgctgt agctgtacca gcgatgacct
     4441 caacttctgg gaaatgagcc ctgatagttt ccacaaaccc attctcaatt aaatcacgag
     4501 tcttaggata agaaagggtg acacgattat cagtgtaaat aggtgattta atgccagatg
     4561 cccacgtaaa agggtcttca ggctttaaat aaacagcttt aatatcaagt aattgagttg
     4621 caatttggct tgctagtgtc atttcttatt ctccttattc ttctttaaca gacaagtgtt
     4681 ggtttcctaa tcttatctgt tagcctgccc actcagcttt tatagcttgg taagtagcca
     4741 ctgggtcttt tgcctgggta attggtcgcc ctaccacaat ataatcactt ccaatgcgtc
     4801 ttgcttggtt tggagtcatc actcgttttt gatcgccaat attactgcct ttaggacgaa
     4861 tgccaggagt taagcaatta aatcctgtag gcgtcaccgc cttgatagct tctacttctt
     4921 gtgccgaaca aaccacccca tctagctgag ctttagctgc ccccttgctg taatgcaaaa
     4981 cagactctaa aagactcgtt tgaatatttt gatcaccacg catttggtct tcactggttg
     5041 aagttagctg cgttaccgca attaaggtag ggccttgacc tagtccttct cgagctgctt
     5101 ttagcatctc tacaccacca gctgcatgaa cagttgccat atcaatatct aattctttaa
     5161 gaactgccat agcagcacga acagtatttg gaatatcatg caattttaaa tccaaaaata
     5221 cattatgccc taacgatttg atataccgaa caatatctgg tccttgcgca taatataatt
     5281 ccataccaat tttcacgtat agcttttctt ctgctggaaa taagtctaaa aatgctttag
     5341 tctcctcaaa tgatgaaaag tctaaagcaa taattgggcg ttcttctttc ataacttatc
     5401 ctttctataa tgtgtcaata tctcattaag caccaaaaag cctcgctacc aaagaagcga
     5461 ggctacagca aactaaaagg gaattccctt tttttatctt gtataccttg tttgcctctc
     5521 tggactcact taaaggtgcc taaatttaaa ctattatagc ttttttaaaa caagatgtca
     5581 aaactttttg ttatttgaac acatctttcc tactatatct ttttttgtat acttacgtca
     5641 actcatttta tcatttttac cgaatcattt attcaaactc acctgtgggt accttagggc
     5701 tttggtaata ttttataaaa gcttcttctt caagattaac cctctggata tgttcataga
     5761 gcacatccgg aataggagct tccttaagtg acaaagcact cacttttaaa gatgaaaaaa
     5821 catcacttaa gaccccaaaa actcgaatgc gtttatctcc aataataatt tgaaagactt
     5881 ctttggactg gcataaatct atcagatgat ccactccttt aatccaatta tcgacaatat
     5941 ccaaagtttt gttcatcaac ttaaaagctg attcttcata ccaaaaggta gactcaatca
     6001 agcgttgctg catatccaag gtatcaatgg ccgcaacaat atctcccaac tcagactgta
     6061 ctaaatgagc tggaaattcc cctccaagta tagaaggagt tcgttctaca agcttcagtt
     6121 catctcgaaa aagagtcaaa tagtggatac tgaccaataa tttttggatt aagatttgat
     6181 gactattttg ttcagtaaca ttcacacgac caccaccctt tgattagaaa aatacctatt
     6241 tgttaatact attaatataa cacaagaaaa ataaaagggc aatgaaattg atagattcaa
     6301 ctctcaaaat tgaatcatat ttatcctagg ccatattgag aaaagactcc agcgcttttt
     6361 caaagttcta aacccatgat gacgtttgtg cttgcgtctt tatttttttt gagctagact
     6421 gtacttatga gaattcaaca actgcattat attatcaaaa ttgttgagtg cggctctatg
     6481 aatgaagctg ctaagcaatt atttatcaca caaccaagtc tatccaatgc ggtcaaggat
     6541 ttggaaatgg agatgggcat taccattttc aaccgaaatc ctaaagggat caccttgaca
     6601 aaagatgggg tggaattttt atcttatgct cgccaaatta tagagcaaac atcactgtta
     6661 gaagaccgct ataaaaacca caatactggc cgagagctct ttagcgtttc atctcaacat
     6721 tatgccttcg tagtcaatgc atttgtctca ctcctcaagc ggaccgacat gactcggtac
     6781 gaactctttt tgcgcgagac aagaacttgg gaaatcattg atgatgtcaa aaactttcga
     6841 tctgaaattg gtgttctctt tatcaacgac tataaccgag atgtcttgac caaattattt
     6901 gatgacaatc atttgactgc ctctccatta tttaaggcac agcctcatat ttttgtcagc
     6961 aaatcaaatc ctctagcaac taaaagccta ttaagcatgg acgacttgag aaattttcct
     7021 tacctgagct atgaccaagg gattcacaac tccttttatt tttcagaaga gatgatgtcc
     7081 cagatgcccc acaacaaatc aattgtggtc agtgaccgtg ccaccctctt taacttaatg
     7141 attggtttag atggctacac cgttgccagt ggtattctaa atagcaatct aaatggtgac
     7201 cagattgtgg ctatcccgct agatgtccct gacgaaattg acattgtttt tatcaagcat
     7261 gaaaaagcca acttgtccaa aatgggggaa cgttttatcg aataccttct cgaagaagta
     7321 acctttgatt aatgtctttt tcaatcgtca tactaaaaaa acacggtagt aagacctgta
     7381 tcggtcaagt tatcgtgttt tttgataaat atcagacaat agattgtctc caaaggctca
     7441 actccttttt aataatggca ttcatgtcat caaagtaaaa aggctcacat cggtagatta
     7501 caccagaaaa agtcgccaag gtgataatgt tttccaaaaa agcctgagaa gaaaaatgag
     7561 tggtgcgata cagttcctct tcatcaaaag gcttaatcaa atgagccaga ggattacgga
     7621 cagccttttc aaaatgtcgt aacaaaaaaa ccaagtcctt gatttcctga ggtaaggagg
     7681 tcaacgtcaa catgtctgct aagcttttgg tcgtcacatt gcgagactgc ttttgagaca
     7741 ggtaagcctt gaaaacctcg tgatcagatt ccaacatggc ctgaaaatgc caggtatcat
     7801 attggtcatt ctttgtatca aaaatataag ccttgaagtt tggaatttct gacgtgatta
     7861 gtctaagaaa aagtcggtaa agaataggcg acactgacct gacgaaatca ataatagcac
     7921 cgttttttac tttaacttct aaatccaaaa tgtaattggc aatctgctca tcttcaagcg
     7981 attggttaag ccataatgaa cagtggtact ggtcttcaat ggtccgattc tctgctgcat
     8041 gttccgccag aaaggcaagg ttcaattctc tgcgctcttt taacatctct agtaaataga
     8101 gggcagtttt agggatattt ggcaaggctt tagcaattct aaaggcgtga ttataagcat
     8161 agacatccaa aaggatgtct agtgtttgat tattagtcat tggcaattaa ggtttccaag
     8221 ccgaccttca tcatatcagt gaaagtggtt tggcgctctt cagctgtagt atcttcggtt
     8281 ggatcattca agttatctga gatcgtcatg attccaaggg ctttgacatg gtgctgagca
     8341 gctaaatagt aaagagctgc tgcttccatt tcgatggctt taacacccaa tttaccaaga
     8401 gccatattac gctcaggcat gttagtgtaa aagacatcag aagaaagcac attcccaacg
     8461 tgagttgtta ctcccatttc tctggcgata tggtaagcct tgtcaagtaa accaaaatca
     8521 gcaatttgtg ggaaatcaaa ttctgggaag tcattacgga taatatttga gttggttgct
     8581 gctgcttggg caagcaccaa ttcacgcaca tgaacttctg ggtcaatcgc acccgcagta
     8641 ccaacacgga tcaatgtttt gacaccgtaa tcaacgatta attcacgagc atagatagag
     8701 atcgaaggca tccccatacc agttcccatg acagaaacgc ggtgcccttt gtaagttcct
     8761 gtgtagccaa acatgttacg cacttcgtta aaacacactg catcttctag gaaattttca
     8821 gcgataaatt tcgcgcgcaa aggatctcca ggtagaagaa ttttatcagc aatatcgcct
     8881 tttttggcag aaatatggat agacataaat tatgatactg agggcgttaa aagaacgatg
     8941 gcaaaatagg aagttggcag aaaatcctga ttttctagac aacttatctt tttgaccaag
     9001 tccttagccc gaattcaaat taatgaactc agccctcacc tttcttattt ttttattttt
     9061 tataaggaag aaaaacagtt ctccgcccgt attcaattca atgaatacag ttagccctac
     9121 ctttcctttt attttgtaga aggtcagagg gcggacagaa agcaactgaa atttagggaa
     9181 ctaacgccat gtgtgagcac aaaagttagt ttatctagtt tccgagcttt ccgcccgtat
     9241 tcaattgaat acaaccccat tcctttcata attgatattg aatagaagaa gagagctaaa
     9301 aatcgagttc aaataagaaa ggactaactc tctttccttt attatttaaa aattaatacg
     9361 aagaaatgtt cgagtccatg cttaatttaa accgaatacg tctctttccc ttcgttggtt
     9421 atgttagtta gaaaagctag aatctgagtt caacattcat agaactcaca ccccgtgatt
     9481 attttttgat ttttttattg cgaacagatg tgccaaactg acgacataaa ataacattcc
     9541 tgtaataatg ctccagttga ttttgttcgt cctacaactc agctaaaata gctttaacaa
     9601 gacctttgaa atcttcttta atatgttcag tcacttcaac aacttcttcg tggttcaatt
     9661 ctgattggaa accagctgca aagttagtga tggctgaaat gccaagtact ttaagtccag
     9721 aatgagcagc cacaataact tctggcacag ttgacatgcc gacagcatct gctcctaata
     9781 ctttgaaagc acggatttct gctggtgtct cataagttgg accagttaag cccatataaa
     9841 caccatcttc tagtttgatg ttcatttttt cagccacttc atgtgcctta ttgcgataaa
     9901 ccttagtata ggcatcagac atatcaggga agcgtggacc aaactcgtcc aagttttcac
     9961 cgattagtgg gttatttccg gtcatattga tatggtctgt gattgccatc aaggtacctg
    10021 ggccgtagcc gataccacca gctgcatttg tgacaagaac gccttcacat cccagagctt
    10081 tcatgacacg aacagggaaa gtcaccactt caagcgggtt tccttcgtaa aaatggaaac
    10141 gaccttgtag ggcaagtact ttacgaccag ctaaatcacc gtagactaat tttccagcat
    10201 ggccaacaac tgttgattta ccccagtttg gaatatctgc ataatcaata acaatagcat
    10261 tttctacttc ttcagcaagt tcaccaaggc ctgaacccag aattaatcca aattcgggag
    10321 tttcaattcc tttagtaact aaaaagtctt ttgtttcgtt aattttagtc atcaatgaca
    10381 tctttttctc cttttacctc aatagggttc acactctcgc catcctcttt catataagga
    10441 ctaggcaggg gaacaggaag aatatccagt aaggtctcag aaggacggca aagttttact
    10501 cctttgcgag tcacaacaat aggacgattg atcaaaattg gatccgtcaa catggcatta
    10561 ataacgtctt tctcagctac tgcttgattt gctaatccat gagcctcaaa ttcaggaaca
    10621 ttggttcgca agagttcttg cgcagagatt gccatcgatt gtaagagctc aattaaagtc
    10681 tcccgattag gtggcgtctg caaatactca ataatagtag gctcaatacc tgcatggcga
    10741 atcatggcaa gaacattacg tgaagtacca cagtttggat tatgataaat cgtgatttct
    10801 tccattatca actaattttc ttattttaag tgaccaagga atgactcccc aatcatggct
    10861 gtatcaactc caaaattttc tgcaacagtt gctgaaatat ccgcaaaatg cccttgtgga
    10921 ataagaccat ttccagtaaa ggatgcagag taggcaagca atggaatgta ttcacgagtg
    10981 tggtcggtgc ctgcataggt tgggtcatta ccatggtcag cagtgatgag aagcaaatcg
    11041 tcttctttca tatttgcgaa gatttcaggt aggcgattgt caaattcatg caagcagtca
    11101 cgataaccct ctgggtcacg acgatgacca aagttggcat caaaatcaac gaggttagta
    11161 aaggagaatc ccttagtaaa ctcaggtaat tgaagagtct taataagcgt gtcaatacca
    11221 tggctgttcg acttattgtg tcccatgtcg tttgtaatac ctgaaccatt aaagatgtca
    11281 ttaatcttac caacggcata agttgggacg cctgcgtcag ccagtttgtt caaaacggta
    11341 tcttggaaag gagacactgc atagtcatga cggttagccg tacgtgtaaa gtttcctggt
    11401 tcgcctacat aaggacgcgc aataatacgg cctaaaaggg cagggcgttc aagcgtgatg
    11461 gagcgagcat attcacaaat cttgtaaagc tcttccacag gaataatgtc ttcatgggct
    11521 gcaatttgaa gcactgggtc tgctgaggtg taaacaatca actcacctgt ttccatttga
    11581 cgcggaccaa aatcatcaat aaccgcagtt cctgaatagg gtttattagc ttcacgaata
    11641 attttgcgac ctgagaattc ttcaatctta gttaaaatct cttctgggaa accattccag
    11701 aaagtgtcaa aaggttccgt aatgttcaag cccataattt cccaatggcc tgtcatggta
    11761 tcttttccaa gagatacttc ttccaatttg gtcacgtaac cagtaggatt gtcttctgtt
    11821 ggaatagttt ttagtggtat cggacgagaa atgtttccaa gtccaatttt tgccatattt
    11881 ggaaccgata agcctgctgt ttctgaaata tgaccgaggg tgtcagaatc tgtatcagct
    11941 acaccagcat taaagaattt gtcagcatct ggcgctgcac caataccgac agagtctaaa
    12001 acaaccaagt gaatacgatt aaattttgac ataagtctcc aatctagggg aggttacggt
    12061 tgactcccca atacctataa aatatattaa cactgttata tgctaagact agcctgcttt
    12121 aggcgcttct aaaacagtaa cgccgtcttt actagcaaca atcaccttat caaccatacc
    12181 attaaagaga ccgtgttcca caacaccaac tgttccatct agcaggtgac caaaagcaac
    12241 aggatcttta atacaaccca aatcaagatc aataatatag ttttgcatgt ctgtcaccaa
    12301 acgactatca cctttcatac gaaaagacgg tttgtaacca gctttttcaa agacacggaa
    12361 caaacgatca gcaccatatt gaacgacttc gactggtaac ttaaaggcac ccagatgctc
    12421 taccatttta gaagcatcaa caacccagat gtattctttt gttggtgttg caacaatttt
    12481 ttccattagt aaggctgcgc cgccaccctt gattccattg aaatccttat ccacttcatc
    12541 agcaccatct acggtgaggt caatgctatc aatatcatct atcgatttta aaggaatgcc
    12601 taagccttct gcttgcttgc tagtcacact tgacgtagtc acaccaacca cttgcagtcc
    12661 ttcttgcttt acgcgacggc caatttcctc aacaaaatag taagccgttg acccagttcc
    12721 aagcccaatg gtcatgccat cagtcacata ttgcgcagcg gtaacaccgg caattttttt
    12781 gagtgcttcc atgattcccc cttataatag aattgcgtct tagcacttta ttataccatg
    12841 aaagcgccaa cttgttaatg aaaacatttg tttttctctc attgacagcc taagtgctat
    12901 agaataggat gatcttttta aaacttatga tttattctaa agtcatcata taagcactta
    12961 cttttcgtgt ttatttagct ttttgaaaat caagtgtttt tgtttgacct ttactgacct
    13021 tttgattata ataatactat aagatgagta aaaataatgt ctgaatcatt ttattagcaa
    13081 agggtttcct atcatgtgaa atcctaacaa cgattctgcg actgcttaca aacatcttat
    13141 agtctatttt ttattgcgag gtaactgata tgacacattt ttctggtaaa gatccttttg
    13201 taaatatgga tgatattttc aaccaattaa tggcaaacat gggtggttat cgtagcgaaa
    13261 atccccgcta tctcgttaac ggtcgcgaaa taactcccga agaattccaa cactatcgtc
    13321 aaacaggaca actccctgta gcgacaacca aagcaacaaa ttctcaaatg ttaacaccta
    13381 aagctgatag tgtattgact caactcggaa ctaacttaac acaagaagct cgtcaagggc
    13441 atcttgaccc cgtcattggt cgtaacaaag aaattcaaga taccgctgaa atcttggcac
    13501 gacgaactaa aaataatcct gtccttgtcg gagatgctgg tgtcggtaaa actgcagtca
    13561 ttgaaggttt agctcaagcc attgttaatg gaggtgtccc agctgctatt aaaaacaagg
    13621 aaatcgtatc aattgatatt tctagtcttg aagctggtac acagtatcgt ggttcctttg
    13681 aagagaccat tcaaaacttg attcaagaag taaaagaagc tgggaatatc atcttatttt
    13741 ttgatgaaat tcatcaaata gttggtgctg gtgccacaag cagtgattca ggttcaaagg
    13801 gacttgcaga tattcttaaa ccagccttgt cacgaggaga attaacactg attggtgcta
    13861 ctactcaaga cgaataccgc aatactattt taaaaaatgc tgctcttgct cgtcgcttta
    13921 atgaagttaa agtgaatgca ccatcagctg aagatacttt tcacatttta atgggtattc
    13981 gtaatcttta tgaacaacac caccatatta cccttcctga taatgttcta aaagctgctg
    14041 ttgattattc tattcaatac atcccacagc gtagcctgcc agataaagcg attgacttac
    14101 tggatatgac agctgctcat ttagctgcgc aacacccggt cactgactta aaaacactcg
    14161 aaactgaaat agctaaacaa aaagagagtc aagaaaaagc tgtcgccaaa gaagactttg
    14221 aaaaagcttt agcagcaaaa acacggattg aaacattaca aaagcaaatt gagcaacata
    14281 accaaagcca aaatgttact gctacagtca atgatatcgc agagtctgta gagcgcttaa
    14341 ctggtattcc tgtctctaac atggggacta atgatttaga aaggctcaaa ggaattagca
    14401 gccgcttaaa aagccatgtc atcggacaag atgaggctgt tgcagcagta gcacgtgcta
    14461 ttcgacgaaa tcgagcaggt tttgatgatg gtaaccgtcc aataggttct ttcctttttg
    14521 tgggtccaac tggtgttggt aaaacagagt tagctaaaca attagcactt gatttatttg
    14581 gttccaaaga tgctattatt cgacttgata tgtccgaata taacgatcgc actgctgtgt
    14641 caaaattgat tgggacaacg gctggttatg ttggctacga tgataataat aataccctaa
    14701 ctgagcgtgt tcgtcgtaac ccttatgcta ttgtcttact agatgaaatt gaaaaagctg
    14761 atcctcaaat cattacactt cttctacaag tgttagatga tggacgattg acagatggac
    14821 aaggaaatac tattaacttt aaaaataccg ttattattgc tacatcaaat gccggttttg
    14881 gccaacaaga tacggaaact tctgagtcta acattatgga tcgcattgca ccttatttca
    14941 gaccagagtt tttgaaccgt tttaatagta tcattaaatt taatcatctg caaaaagaaa
    15001 atttagaaga aattgttgat ttaatgctag ctgaagtaaa tcaaaccacc gcaaaaaaag
    15061 gtattagttt aacgattgct gatgacgcta aagctcattt gatagattta gggtacaatc
    15121 acgctatggg agctcgtcca ttacgacgta ttatcgaaca ggaaattcgt gaccgtataa
    15181 ctgattatta tcttgaccat ccagaagtca aaaaacttca ggcaatccta aaagaaggac
    15241 aactagtgat taggcaaaaa gatcagtaat aaacttcttc aattgaataa ttttcaaaac
    15301 atgaaaaaat ccgtcttgtg actacgttat acacttgacg gacttttttt tagcgctttt
    15361 ttaaaaataa ttttttcatc gcctaataac tcaagtttct ttccaaatct ggtgtaatca
    15421 aaataaccat taggtgtgag caatcctttt gaaaaagaag tatgtcccgc tgctacttct
    15481 tctttgatat caatggtgtg caaaatacga ttaacttttc ctttgagaac aacagcagat
    15541 aaatgtcctg ttttttgatt atatttgcct ccgatctgag aagctaattt ctcaaaagct
    15601 tgatctaaaa tcatttctaa ttcatggcta gctggcatac tattctcaat aatttggcgt
    15661 tctttactac tcaagtcacc aacaactaaa tgattttcct ttaatgtctt taataattca
    15721 ttttggtgat aagcagctaa acgtttgaca aaaatgtctc gttcaacttg aacactaaaa
    15781 ctcaagtcaa cgttgttatt tttaactgtt agtatcatct gagatgacgt taataaacta
    15841 tcatcaataa gagggctctg atgcaaacca gtaagacgtt tagcaaaatc atcgcctaac
    15901 ttctgatcaa tgcttgttgt tcgccagata ccttcaatag agctattacg atatcgaaca
    15961 ccaaaaagta cagcaagcaa gataagaaaa ataataaata caaaaagggc attgcattga
    16021 tggcataaca atgactttcc tttagagcgc ccttgggcta cttgtgtcat gactcatctc
    16081 cttaatataa aatactagca tgtcatcatt aaggcgtcaa gtaaaatcgg taaacctaac
    16141 tatgattttt tatgttttcg ataagaaaaa caccctctac tgagaatgtt ttagcataga
    16201 taaatcaaca cctatcgcta gacctgctct aaaatagcat cccaagaatc atcgatacca
    16261 atacgttcta ccgaagaaaa tactataaaa gtatcagatt tgtcaaaatt caaagctttc
    16321 ttgaccacag actcatgttt gttccatttg ccacgaggaa tcttatctgc tttggttgcc
    16381 acaacaataa caggaatgtc atagtacttc aaaaagtcat acatctgaat atcttctttt
    16441 gaaggggcat gacgtaaatc aaccaaactc acgacagcac gcagattatc tctggtggtt
    16501 aagtattctt cgatcatctt tccccatttg gcccgttcac ttttagaaac cttggcatag
    16561 ccataaccag ggacatccac aaatctaagc ttgtcatcaa tatcgaaaaa atttaatagt
    16621 tgggtttttc ctggcttgct tgaggttctt gccaaatttt tgcgccccaa tatggtatta
    16681 ataaaacttg atttaccaac atttgaacgt ccagcgaggg caatttctgg caaatcatct
    16741 tgggggtaat gagatttatt ggcagcactc aataaaattg aggcgttatg ggtatttaag
    16801 acttgttctt cagccattat ttctccttaa gctgtctcta aaacgggttt tgacttgcct
    16861 tcgacagcag ccttggtgat acgcactttt gtgacatctt cttggcttgg aatttcaaac
    16921 ataatgtcta acatcgtttc ttcaataata gaacgaagac cacgtgctcc tgtcttacgt
    16981 tcaatggctt tattggcaat ggcttctaag gcttccttat caaatgccaa ttcgacgcca
    17041 tcgtaagaaa gaagggcctg atattgcttg accagggcat ttcttggttc tgtcaaaatt
    17101 tgaatcaaat ctgatgtgtt tagttgttca agggctgcca caactggtaa gcggccaata
    17161 aattctggaa taagcccaaa cttttgaata tcttctgaaa taatttcttg catataagaa
    17221 gcattgtcat caattttacg gctgttttga ccaaaaccaa taactttttc acctaaacgt
    17281 tgtttaacaa tctcctcgat gccatcaaaa gccccgccaa caataaacaa gatatttttt
    17341 gtatcaattt ggatcatttc ttgattagga tgcttccgcc caccttgtgg gggaacactt
    17401 gctaccgtac cttcaataat tttaagaagg gcttgctgta caccttcacc agatacatca
    17461 cgtgtgatag atacgttctc acctttttta gcaatcttat ctatttcatc aacataaata
    17521 ataccacgct ctgctcgttc gacattatag tcagcagcct gaatcagttt gagtaaaata
    17581 ttttccacat cttctccaac ataccctgct tcagtcaaag aagttgcatc tgcaatagca
    17641 aatggtacat tgaggctttt agccagagtt tgtgctaaga aggtttttcc tgaacctgtt
    17701 ggtccaatca tcaaaatgtt ggacttttgt aaatccacat catcgtcatc acgactttct
    17761 gtaaacgaga cacgcttata atgattgtac acagcaactg ataaagcacg tttagcacga
    17821 tcttgaccaa ccacatattg atttaaaaca tcaagaagct cttttggttt tggaacttct
    17881 gtcaaatcgg caaggacttc ttcagccaat tcttctttta taatttcttg tgataaagct
    17941 acgcattcat tgcagatgaa aacattattt cctgcgataa tttttttaac gtcatcctgg
    18001 cttttaccac aaaatgaaca gtatacttta atatcgttag ttctacttcc tgccatttct
    18061 tataattctc ttactttctc ttatctttta atgaatttta atattagtca atgtgttgta
    18121 ttggtttttg gtgattcttg cttgatagct aaatcttcac cagtgctgtc tttgcaagtc
    18181 gcatctcaaa acaatgtacc atagaaggcg tgaatactat taaccagatt agtaaacgca
    18241 tttaataaga acagacttcc taagccataa cgattctttt taaaagctgg gatggcacaa
    18301 agaacacaaa tcacgcacaa aaaagccgta aatactccaa aaatactacg ttgcatcgct
    18361 tatcatctcc tcagactatt tgtgttttaa agcagtaacg gtaaaatcat aaggattttt
    18421 agcgtctcga gcatagaacg tttgtctttc ttgcgtgaaa tgactaaaat ctagattggg
    18481 tcggtaggta tctcctttaa aacgatgatg gataactgtt tttatgatac gatcaaaata
    18541 accattaaac gcttctaaaa ccttattccc accaatgata taaagtgttt tatcctgcgc
    18601 atggtaccac tccaagactt tttcaatact agtcattgtc aacacctcat ctacttgata
    18661 atctctattt cttgtcatga caagggtttg acgttgagga agtcttttgc aattcattcc
    18721 ttcaaaagtc acacggccca ttaagattgc ttgatgtagc gttgtctttt taaaatgttc
    18781 taactctttt ggtaaatacc atggtaactt acccgcaaca ccaataagcc ctgcttcatc
    18841 ctctgcccaa atagcaataa tttcctttgt cattaattat ttccttcatt ttaaactcta
    18901 tttattttac caaatttatg aacaaaatgc tcacaaaaaa tctaaataga gtttaaatag
    18961 caaggtcaaa gtgcaactga ggcttcactg gatcataatt ttgtaattca aaatcatctg
    19021 gtttaatatc aaagaaatta gtcccatctg gaacatttaa aacaagctta ggctgactag
    19081 caactggctg tcgttttagt aattcttgag cctgatcaaa ttggttgtca taaatatgta
    19141 aattgttaac aaaataaaag aacttaccta ttttccatcc aaaatgttta gcaatcatca
    19201 tctgcaaggc aacgtattgc atggcattga tgtgatgagc aactaatatg tcattagaac
    19261 gttgcgtcaa actagcatct aaataaagat cttcccctac acgtctaaca tcaaacatga
    19321 tttgaaaggc acatggcaac aatccttttg tctcctcaaa tgcttcatag tcccagagag
    19381 aaatgacatt acgacgattc caaggatttt ctgctaattg ctttagtatt tttgagatga
    19441 tatcatgttt tttgactaca gcaccataac gttgcccaat agtacgtgtc tggtcaactt
    19501 cccattcatt ccaataatga acattatatt tagcttctag cacatctaaa ctgttagact
    19561 gatcttgata tatccaaaat aattccttta tagcagattt aattggaatg ggtcgtaaag
    19621 ttgtgatggg aaactctcct ttagctaaat catattcagc aaacgcccca gtaatatact
    19681 tagaatgagc tgttcggcca tctttatatt taggacgtgc ttgctcactc aatgatcctt
    19741 cgtttataat tttttgaata ttagctttaa aaatctggtc agcttttgtc atctctaata
    19801 acctttctgt aagcatactt catactattc taactaattt taccaaaaaa taccagaata
    19861 aataaacatt cgaaaaactt catgtggtca tgaatatttt aactattaaa ggataaaaca
    19921 aataacttta tcagtctaat tttgcagtaa aatgtgatag aatgggtaag actataaaaa
    19981 taactaaaag aaggacaaat atgacaattg gaattgataa gattggtttt gcaaccagtc
    20041 aatatgtctt gaaattggaa gatttagcgc ttgcacgcca agtggatcca gcaaaattta
    20101 gtcaagggct actcattgag tcttttagtg tggcaccaat cactgaagac attattactt
    20161 tagctgcttc tgcagcagat caaatcttaa ccgacgaaga tcgatctaag attgatatgg
    20221 ttattttggc aactgaatcg agtactgatc agtcaaaggc atcagctatc tatgtacatc
    20281 acttagttgg tatccagcct tttgcacgtt cctttgaagt aaaacaagcc tgctatagcg
    20341 caactgctgc tctagactat gctaaactgc atgtggcttc taagccagat tctcgtgtcc
    20401 ttgttattgc tagtgatatt gctagatacg gtgtagggtc tcctggcgaa tcaactcaag
    20461 gctctggtag tattgctctt ttggtaactg ctaaccctcg tattcttgct ctaaataaag
    20521 ataatgtggc tcaaactagg gatattatgg acttttggag gcctaactat agtttcacac
    20581 cttatgttga tggtatttac tctaccaagc aatatctcaa ttgcttagaa accacgtggc
    20641 aagcttatca gaaaagagaa aaccttcagt tatctgattt tgctgcagtt tgtttccata
    20701 ttccatttcc caagttagcc ctaaaaggtc taaataacat tatggataac acagtacctc
    20761 ctgaacacag agaaaaacta acagaagcct ttcaagcttc tattacttat agcaaacaaa
    20821 ttggaaatat ttatactggc tcactttatc taggattgtt atctttactt gaaaatagta
    20881 aagtattaca atctggagat aaaattggtt tttttagcta tggttccggt gccgtaagtg
    20941 aattttattc cggtcagtta gttgctgggt acgataaaat gttaatgact aatcgacaag
    21001 ctttactaga tcaacgaaca cgtctttccg tttctaaata cgaagacctt ttctacgaac
    21061 aagtccaatt agatgataat ggtaatgcca attttgacat ttacttaact ggaaaatttg
    21121 ctctaacagc catcaaggag catcaaagga tctatcatac caatgacaaa aactaatctt
    21181 aactggagcg gtttttcaaa gaaaacattc gaagaacgcc tccaacttat cgaaaaattt
    21241 aaactactta atgctgaaaa cttaaatcaa ctcaaaacag acgttctttt gcctatccaa
    21301 acagctaatc aaatgactga aaatgtctta ggacgattgg ctttgccctt tagcatagct
    21361 cctgattttc ttgtcaacgg ttcaacttat cagatgcctt ttgtcacgga agaaccttct
    21421 gttgttgctg cagcatcttt cgcagcaaaa ctaatcaaac gctcaggtgg ttttaaagct
    21481 caaaccctaa accgacaaat gattggtcaa attgttcttt acgatatcga ccaaatagat
    21541 aacgctaaag ccgccatcct tcataaaaca aaaaagctaa ttgcattggc aaataaagct
    21601 tatccttcca ttgttaaaag aggtggaggc gctagaacca ttcatttgga agaaaaagga
    21661 gaatttttga ttttctatct gactgttgat acccaagaag ctatgggagc aaatatggtc
    21721 aatactatga tggaagctct tgttcctgat ttaacaagac tgtctaaggg gcattgtcta
    21781 atggcgattt tatctaatta cgcaacagag tcgcttgtta ctactagttg tgagattccc
    21841 gtgcgccttt tagatcacga taaaacaaaa tccctacagt tagctcaaaa aatagagcta
    21901 gccagccgac tagctcaagt agatccttac cgggctacta ctcataataa aggtattttt
    21961 aatggcattg atgcagtggt aatagccaca ggaaatgact ggcgtgctat tgaagcaggg
    22021 gcccatgctt atgcctcaag aaatggtagc tatcaaggac ttagtcagtg gcattttgac
    22081 caagataaac aagttctgct tggccaaatg accctcccta tgcctattgc tagtaagggg
    22141 ggatctatcg ggcttaaccc tactgtttct atcgcacatg atcttcttaa tcaacctgat
    22201 gccaaaacat tagcccaatt gattgcatct gtggggttag ctcaaaactt tgctgcacta
    22261 aaagctctga cctcatctgg catccaagct ggtcacatga aactacatgc gaaatcatta
    22321 gctcttttgg cgggggcaac ccaagacgaa attgctcctt tagttaatgc tttactagct
    22381 gataaaccaa taaatctaga aaaagcacat ttttacttat cccagctaag acagtcttag
    22441 atttaaacaa ctaatataag gcaaacaccc atgtaaacaa ttggtttaca tgggtgttta
    22501 atctttgttt ctatacatac aagtcttaga aatagtctcc ataacatact ctatttactc
    22561 atctactcta ttctgagttt gatgaggtat ttataaatat tttatattat gttctaaaaa
    22621 agctctatca tctttgtagt aggtggcact attgtagagg tgatgaagcc taattgacct
    22681 gctgcaagcg tccatatagt aagtagtcga ctccctttaa ttctttaata gttttacagt
    22741 caagagcaca cataatgatt tttaattctt ctttccagcc attaacgata gcaatcacac
    22801 gctcggttgg gtatttttcg accaattcta aaacggtgcg tgagagtccc actgcacgtg
    22861 ctcctaggac gaaacattta atcatgtcca aggggtgtct gacaccaccc gaagctaaga
    22921 tttccacttg gtccatcagt ccttgtgcat ttagcaagca ctgaacggtg gtttgtcccc
    22981 aatcgtttaa gtaagagcgg tctcctcctc tttgattttc aatataggca aatgaggtcc
    23041 ctcctcttcc tgaaatatca aaggtttgaa tgcctaggtc atgtgctagc ttgatactat
    23101 tgacatccat gccaaaacca acttctttga gaatgacagg aactggtatt tgactagcgt
    23161 attcagcgag gtgttttttc caggtatgaa agacgcgctc accctctggc atcagcaact
    23221 cttgcatcac attcacatga acctgtaaaa agaggggctg catttcttga accgtttgtt
    23281 gtcctagcgc cacaggttta tctagaccaa tattcgtggc tagtttcaag ttatctgcca
    23341 cctcatgtaa acgataggaa tcgtcgttag gattttttaa agcagcgcta taagaccctg
    23401 tcaccatgac aatccctgtt gctgctgcta ctttggccaa tttttcattg acagctttgc
    23461 ctttttgact tcctcctgtc atggcattga tgtaaaaggg aaagtcgaag tcttgcccgg
    23521 caaaatgagt actgagatca atatcagaca aatcatagct aggtaaggaa tgatgtatga
    23581 gttctatgtc atcaaaagca ttataaggcg attggtactt gagggcatat ttgatgtgat
    23641 catctttacg gttggtcatt ctctccccac ctttcttgat aaagtaatgc gatatcagct
    23701 tcttgccatt tggaaataag ggtatctctg gcattctgat taaaggcaag cgcgatgcca
    23761 caatctccac caccagaacc tgaagattta gcaacagcat cttgcttctg acaagcagct
    23821 accaaggtta ctagcttagg atggtagata gctgaatgaa gctcttttag gagatgactt
    23881 gctcctgcta aacttttctt gagttcttcc ttatgacctt cttgcaaagc taccatagct
    23941 gattgcgtta gctggtaact tgttcttaag aaagctgggg taatgctcgc tgtcacttgt
    24001 tgaatcatct gccttgaaat agcaggtatt ttagtccagc caaccaaaaa gtcacaaggc
    24061 aaggctggtt gaatgacttg gatatggtaa ccccaatctt tgacgagaag tttttttaag
    24121 ggcatggtct gcagccagtt actgacctgt tctcggtcaa aggaggtata ggcgactaaa
    24181 gtctgataag cgatacaggc aatatccccc atagacccat tatctccttg cttaagcaag
    24241 gtataagccg ctagtttaaa gagtaactct ggggttaaag tgatctgata ataggccgat
    24301 aaagccttta aggttaagag agtgacgcta ccacttgaac caatgccaaa ttttttgcca
    24361 tcgcgctcca tttttcccat tatgattaag gaaaatggct ccagttggtc aattgactgt
    24421 cctagataat cagcaaaggt tttaaccgtt gcttgaatca gtgcataaga agcatcgggt
    24481 gtcatgcccg ctttatgggc aaacatatct gaagctaatt gaatatgggc tgctgggcta
    24541 atttctgctg tcatcatcag tggaataaag tgaattaagg ctttttgtcc tggtgttaag
    24601 atagcatatt cgcctgtgag gtatagtttc ccacctgttt gcacacaata attagacatc
    24661 tggtaaatcc tttgtttttg aaacgataat acggtagttc ttgccaagtc gttctgctag
    24721 ttgagccaag tctttttcta aacataggac cttcacattt ggacctgcgt ccatggtaaa
    24781 ataacaagca aaaccttctt gacgcagttc tttcacagcc tccatagcct ggtaagactc
    24841 ttttgttagg taagaaaagg gaggattggc tgtctttgtc gtggcatgca tggccaaggc
    24901 attagcttct gttaactgac caactttctc aaaattatta gttttgagat aggtaagcat
    24961 atgttggtaa tcgattgccg attgttctac ccattcatca aatgtagttg aggtatcgcg
    25021 gcataacttc atgccctctc ggctagaaat tggctttttc gcagcattta agaccagcat
    25081 aatcatggcc attttcaagt cagtctcaac cttgtaaata gcaccactat ctttgtccca
    25141 agcagcaact gggccaaaaa aagaacgaga agatgatcct gaggcgaact tagccttttg
    25201 agctaaagct ttctgatcta gctgagtgtc aaataattga tcacaggctt taaccaaggc
    25261 tgataagcca ctggaacttg atgataaacc tgcagctgtt ggcatattat tttgagtttc
    25321 catctttaca aaagcctgac caggttggcg aaattggtca atgatagtag aaattttggt
    25381 atgttcttcg tcattttgca agacaccgtt aatgtaaaac tgatcactgg ttgcagtatc
    25441 tggtaagaag gaaacgctgg ttgtggtgaa catgttttcc aaagtcaaag aaatgctaga
    25501 ggtcgaagga atcatcttag cttgattctc ttttccccaa tatttgataa tagcaatgtt
    25561 agcataggat gttacggtta taacatttgg atccacgtgt ttacggctcc ttcttctttt
    25621 aatctgtgac tgattttttc ggccatgtct ttggtatctg ctagggcaat catacagcca
    25681 cccaagccac cgcctgtcat cttagcgcct aaagcacctg ctcttagggc agcctccaca
    25741 agttggtcag ctttactgat gctaacgcca atggccttta aagcagagtg cgcttgtgtc
    25801 atgagctgac cgatagccac cttatttttt tggttaatcg ctctttcaag ggcttgtgtc
    25861 aaagctccta gtttagccag atagggcaaa ttcgtttcct caaactgtgc taccttattg
    25921 acggcctcac gtgtatgacc gtgaatccct gtatctgcaa tgacaagata accatttaag
    25981 gcgatttcga tagtttcaaa gccaatgttt cggataaact taatggcatg gtcactaagg
    26041 catgtcttgg catctaaacc actaggattg gtgtgggcaa taatttctgc cttgttgact
    26101 aaaatttcca acaaatcatc cgagaggggt tcttgacaat aagaaaaaac ggctctaata
    26161 gctgcaatag aaacggctgc cgaagacccc ataccacgct tttgtggcac ttgtgaaaca
    26221 atctcataag caattggttc ttgtagtcgc tgcaaataat ccaaggcagc ataaatggct
    26281 gttgatagag tatcataaaa atcaaagacc aatggcttat cagctggaaa aatatgacaa
    26341 accacctcaa tatctgttaa aggcaaagca atagctgggt agccatacac aacagcatgc
    26401 tcacctatca aaatgatctt actgtgtgcc ttaccatatc caatgttttc attcattttt
    26461 tatcttttca ttactaattc ttctaaactt ttaccttact attttacact aaatgattag
    26521 aaaatgcgat gatatatctt tttaaaatca tttcttcact gaaattaaca ataaagacta
    26581 tctactcttt ttaggatcat aacaaaaatt ttcttatttc aaactacctt ctttaatcac
    26641 tcttctacta aattaaacgt taaaaccagc ctcatgggct ggttaagcat cgtttattac
    26701 ctttacctag acattattac tagctaaagg tactgaaaaa tgtttaagtc aaatcaccac
    26761 tgtaaaaaca atagcatcgt ttttataatt tacagttatc gttcctttaa ataacttaac
    26821 catactttct gccatagata aaccaattcc ataacctttt tctttgctat tatgggattc
    26881 gtcttcgcga taaaagcgtt caaaaaagcg gctgtaatca atggattttc cttccaaata
    26941 ggtattagaa acttctaatt tcgctcgttt tcgtcttctt ccaatagtgg ttaaagatac
    27001 cttgaccaag cctttaggat cacaatattt attggcatta tcaactaaaa ttgtcacaag
    27061 ttcaaataat gacttttcct ccgctttaat cataatattc ggctgaatcg tcaaatcaaa
    27121 acgtttacca tctttcaaaa ccagactctt aaaatcttca gctgcatctt gagcaataac
    27181 tgaaaagtct accatatgta ataccacatc tggctgttcc tccaaacgag ccaaagtaat
    27241 catttgatta atcaagcctg tcaatcgctt cacctgatca cttgtactct tggtccattc
    27301 tgattctcca gtcattaatt cgaccaattc attattggct gagataatgg ctagtggtgt
    27361 ttttaactcg tggcctgcat tagtaataaa gcggcgctgc ttctcataat tttggacaaa
    27421 aggtttgatg accataccgg aaaaaagact cactaaaaca acaaaaaaga taaatcctcc
    27481 aaaggccaac atcattgaaa cagctaataa atctcctaca ctacgaaaat aaaaggtagt
    27541 atctaaaata acaaccagtt tttcttcatt tggcagctga gtaatcaagt acgaataaac
    27601 actatcttgg tgacggtaac tacctttttc ttccccagac ttagcaaaaa gtctagcaaa
    27661 atattgggct tcttctctat ctaaagctga aatattagca gtattagaag aaagtagatg
    27721 tccattagca ttaaaaatga cactataata ccgaaactgg cttaggctat cttcagacag
    27781 tttcgttcca agtcgtttag agctttccgt agtgccaggt aatttacctt tatttgagga
    27841 aattaaatgt aaaatacggt taatttcttg ttgactttgg taacagcgtg ccgtgttaat
    27901 aataccaaca attgaactta aaataataaa aatggcaata gaagcaatca tgataaaacg
    27961 aatacggata cgattaaaca tgtcacctcc tatttttcta ataaacaata gctagtatct
    28021 ttatcacctg caataatgac atttgcttga atagctaata atttttgacg aagataagaa
    28081 atataaaccc aaacaataga agtatcataa tcttcttggt ctgaccaaac atgttggtaa
    28141 agcgttttag tatccaagta ctttccttga tttaacatta aaaaggccat taatttacct
    28201 tctttagaag ctaatcgtat agcattaccg gcactcaatt cttgctcatt aatatttaat
    28261 gtgacaccag caaattgtaa tacctgagga gtaaaacttt ctactcgtct ttccatcgac
    28321 cttaatctag ctaaaagttc ttttaatgag aaaggtttag tcagataatc atcagctccc
    28381 gcatctagtc cggtaacacg gtcattaatt tctgccatag ccgtcagcat aataatatgt
    28441 gagcaatttc ctgaagcgcg aatctccttt aaagcctcaa tgccagactt aatcggcatc
    28501 atgatatcta aaatcataat atcatatgca ttgtctttgg ctttatcaat tgcctcttga
    28561 ccgttaaaaa ccacatcaac gtcataacct tgatgagtca tggcagttgt caaaacatta
    28621 gacatttgcc attcgtcttc agctaacaaa attttcatag ttactcttcc cccgtcgttt
    28681 cttgaatcaa ttgacgaatg gtttgcatgg taacatcaca agatgccaac tcgtctgcac
    28741 aacgctttaa ctctcttgta atcatttctg cattagcaac ttgatgtttg tacttcattt
    28801 gatgttccaa gctagcccaa gagtcttgag caatggttcg caactgcact tctataaaat
    28861 aacatccttt tttttcccct aaaatatctg gaaaatgtgt ttctaattcc aaaatgagat
    28921 gatatgatct atagccatta ggcttggcat ttaaaatata atctttttca gtgttaactg
    28981 acataccagg aatgcttttg agcaagtcta ccatccgata aatatcatca ataaaaccac
    29041 aaataatgcg aataccgata ctatctttaa tgatttttaa cgcagatttg cttgttagag
    29101 gaagctgttt gcgttgacat ttttcaatca tcgaagcttc cgatttaata cgggatgtaa
    29161 agtgttcgta tagtttaaac cctgtttctt ttttgctttt gatattctca gcaataatca
    29221 catctgttat tgtctgtagt accaacggca agtacacttc aaatccgcta tatatagagc
    29281 tggtagaata atgttctagt ctttctttca tacgcttatt ataacaaatt ttctcaacaa
    29341 atgcttaaat ctctgcaatg atcggttatc tttatttcta actatataac tgcaaatgat
    29401 ctatatcgtt tgtttttaaa tcgctttcat atatttttta tacgttattt tttaaaaata
    29461 ccattgaatt acaaacaaaa tcatagtaaa cttgatctat aacgattacg ttaacttatt
    29521 aggagatttt atgaaaaaat attttatttt aaaaagtagt gtattgagta tcctgactag
    29581 ttttactcta ttagttacag acgttcaagc agatcaagtt gatgtgcaat tccttggcgt
    29641 caatgatttt cacggcgctc ttgataatac cggaacagct tacacaccaa gtggtaaaat
    29701 accaaatgct gggacggctg ctcaattagg tgcttatatg gatgacgctg agatagattt
    29761 caagcaagca aatcaagacg gaacaagtat acgtgttcaa gctggagata tggtcggagc
    29821 cagtcctgct aactctgcac ttttacaaga tgagcctact gtgaaagtct ttaacaaaat
    29881 gaaatttgaa tatggcactc ttggtaatca tgaatttgac gaaggactag atgaatttaa
    29941 ccgtatcatg acaggtcaag cgcctgatcc tgaatcaaca attaatgata tcaccaaaca
    30001 atatgagcac gaagcttcgc atcaaaccat cgtcattgct aatgtcattg ataaaaaaac
    30061 caatgatatc ccctatggtt ggaaacctta tgctataaaa gacatagcca ttaatgacaa
    30121 aatcgttaag attggcttca ttggtgttgt gactacggag attccaaatc tcgttttaaa
    30181 gcaaaactat gaacactatc aatttttaga tgtagctgaa accattgcca aatatgctaa
    30241 agaactgcaa gaacaacatg ttcatgctat tgtggtttta gctcatattc ctgcaacaag
    30301 taaagatggt gttgttgatc atgaaatggc tacggttatg gaaaaagtga accaaatcta
    30361 tcccgaacat agtattgata ttatttttgc aggacataat catcaataca ctaatggaac
    30421 tatcggtaaa acacgtatcg ttcaagccct ctctcaagga aaagcttatg cagatgtccg
    30481 tggtacgcta gatactgata ccaatgattt tattaaaact ccatcagcaa atgttgttgc
    30541 tgtagcacca ggtatcaaaa cagaaaattc agatatcaaa gctataataa atcatgctaa
    30601 tgatattgtt aaaacagtta ctgaacgaaa aatcggaact gcaactaatt cttcaactat
    30661 ttctaaaaca gaaaatattg ataaagaatc ccctgtcggt aacttagtaa caacggctca
    30721 gcttactatt gctaagaaaa cttttccaac tgttgacttt gctatgacca ataatggtgg
    30781 tattcgaagt gacctagttg tcaaaaatga ccggaccatc acctggggat ctgcacaggc
    30841 tgtacaacca tttggtaata tccttcaagt cattcaaatg actggtcaac acatttacga
    30901 tgtcctaaat cagcaatacg atgaaaacca gacctatttt cttcaaatgt caggtttaac
    30961 atacacttat acagataatg atcctaagaa ctctgatacc cccttcaaga tagttaaggt
    31021 ttataaagac aatggtgaag aaattaactt aacaactact tacaccgttg ttgtcaacga
    31081 ctttctttat ggtggcggtg atggcttttc agcatttaaa aaagctaaat tagtcggagc
    31141 tattaacaca gatactgaag ctttcatcac atatatcaca aatttacaag catcaggtaa
    31201 aactgttaat gctactatca aaggggttaa aaattatgta acttcaaacc ttgaaagctc
    31261 aacaaaaatt aatagtgctg gtaaacacag tatcattagt aaggttttta gaaatcgtga
    31321 tggcaatata gtgtctagtg aagtcatttc agaccttttg acttctactg aaaacactaa
    31381 taacagcctt ggcaaaaaag aaacaacgat aaacaaaaat actatctcta gttccactct
    31441 tccaataaca ggggacaatt ataaaatgtc tcctattatg acaatccttg ccttgataag
    31501 cttaggtgga ctaaacgctt ttattaaaaa aaggaaatcc tagcgtttac tagtaatcga
    31561 tcacccttat ataatcaggc atctttgcca aaaaaaccta aagcgtccta ctctaggttt
    31621 tttgttaaat taaaatacct tctagatgat ctaattcgtg ctggcatatt tgagcagtta
    31681 agcctgttaa gcttaatcgc tttggtcgcc aattatggtc caaatactca acagtaatct
    31741 tatcataccg ctgtgttttg cgatagccag ataacgacaa acaagattct ttagtttggt
    31801 aaattccctt tttagaaacc atcacaggat taaacataac caaatcaata aatcccatac
    31861 tcacaataac aatgcgcttt tgttcaccaa tcatattggc agccatccca agacattcct
    31921 gtctataaaa ggctaaggta tcttgtaaat cttggccaat ccatagatct tctttcttgg
    31981 cgacttgcgc tttttgctgt aataaaaaat gatctgttat gatttctcta atcattctta
    32041 tctccttaaa ccttcttttt aattcataaa ctacatgttc aatggactat tatcaccata
    32101 tgatagactt agtatcatct gtttaaaaca tcaggtgatt ccttatttca agatatcttg
    32161 ggcaacttta tgaaattctg caatatgagt accaaataaa aattgacctg catcagcaga
    32221 ttgttgctaa gttctcatca caatattatc gaatttactg tctgcttctt caaatgtcta
    32281 agagagatag ttattgcttt gtgagatttt caaaccagat actgctttct cttgcatttg
    32341 caaccttaac aggtccaaat aaaacacctg ctgtttgaaa tactttaata gctgatatgt
    32401 tgttaatagt tagtattata aattttctga atatttctgt caagtttttc agttgactta
    32461 acttttttac ttgatttttc ctcacgtaat aatagaaaag aagcgccata atgtaaacta
    32521 caccccaaac gttagataaa aaaatctaac gtttggggtg tttttgtatg acattaagct
    32581 atgaagataa gctagatatt tagcgctaaa aaaaccgagg gaactccgtt tgaaagaagc
    32641 atctctgcaa agaagaagac aaaaaaccat tataaagaat ggacaaagac gagttctgat
    32701 tagattttct tttaagaacg gctaaagtga ctcgttctac ctactattat catcgattat
    32761 tgcaacaata aacgtatcaa aataaaacga aaaggactta gtcctctaca acacagaact
    32821 aaatccttta cttcaaatag agtagccaac ttttggggct cagtgcaaga gcacttcttt
    32881 tctattatca cttgtttatt ataaacataa cattaccata gtattcttat atgtctagtc
    32941 cactcaaata ctcaaaccgt tcatacgcca ataataaatc attattgtgc tgatcgagtt
    33001 ccttttgtaa ttgagctaac tggtcataat cgctaactac agttaacatt tggttttcaa
    33061 tttcttcaat attagcctca atagttgcta ttttatcttc tatctgagcc cattcttgtt
    33121 tttcaaggta ggacatgcgc tttctttcct ctttttgagg aagtggcact tcttcagtga
    33181 ctgttgtttt aaccaagtca gcctcaactg tttctttttc aaaaactttt tcatcaaggt
    33241 aatcactgta attgccataa aaaacacgaa tatcgccttc ttcaaaggct aaaatcttag
    33301 tagctacttt gtctaggaaa taacgatcgt gactaaccgt aatgactggt cctgcaaagt
    33361 tagctaaaaa gttttctaag accgtcaagg tggcaatgtc taaatcattt gttggctcat
    33421 caaggagaag aacatttggc ttttcaatga gcagttttag caagtagagc cgttttttct
    33481 ccccaccaga taatttagca atcagcgtgc catgacttga tctcggaaaa agaaattgtt
    33541 ctaaaagctc actgatactc gttgttccca cacttgtttt aacctcatca gccacttctt
    33601 gaaggtaatt aatgacccgt ttggtctcat ccatatcttt gagctgctga gagaaataac
    33661 ctacacgaat agtatctcca atatcaagct tcccagaagt tggttcaaga tctccattaa
    33721 ttaaattcaa cagggtagat tttccgacgc cgttatctcc aacaattcca atacgatctt
    33781 tattttgaat aatcaagtta aaatccttaa tcaactgtcg gtcgccataa gcaaaagaaa
    33841 ggtcttcaaa gtgaatcacc ttcttcccaa ttcggctcgt ttcgaaagcc atctccaatt
    33901 tatctgcaga actgtcttgg tgaacttctt ttttcaagtc agtgaaacga ttgattctag
    33961 cctgctgttt ggttgcacgc gcctgtggct gcgtcctcat ccaagctaat tcttgtttat
    34021 agagttgctt cttcttgtgt aaattagtag catctcgttc gtcttgttct gcttttaagc
    34081 gcacatagtc ttggtaattg ccttgatatt ctgtcagtcc cgctttatcc aattcaaaaa
    34141 tacgggtagc cacatgatca aggaaataac ggtcatgggt aataaaaagg acggtttttt
    34201 tagctgtctt gagataggtt gttaaccaag cgatgatgtc aatatcgaga tggttggtcg
    34261 gctcatccaa caagagtaag tcagcagctc ctagcaatac ttgagctaac tggacacgtc
    34321 ttctcatacc acctgatagg tctcccactt tttgttccaa atccgtgatg cctaattttg
    34381 ataggactgt tttgacatca ctttcaatag accaagcatc taagcgatcc atttcagaca
    34441 tgagggactc taaggtctct tgtttatctt cagtataatt cgccatcaat agttcatact
    34501 gacgaatcag ctgaatcgcc ttaacatcag atgacaatac cgtatctaaa acagaggatg
    34561 catcgttaaa ttcaggatct tgtgttaagt aagcgatttt gtaatcattg gctttagaaa
    34621 atggtgaatg gtctccgtca aaaccaagcc ttcccgacaa gacatctaaa agagttgttt
    34681 ttcctgttcc attaacccca ataatcccaa tacggtcaaa gtcatgaata ataaaggaaa
    34741 tatcctgaaa gactgtttta tctcccaccg tttttgtcaa tttctccacc aaaaaatggc
    34801 tcatgttgct aattcctctc taacaaatgc ttcaattgta gtgaaatcat tatctaggcg
    34861 tccctctaca atcgctaatt caactttctc aagcataagc cctagctgag gacctggttt
    34921 catcccaaaa tccttaatca ggtgagaacc attaaggacg atatcgtatt tgttatgaat
    34981 ggctagcgct tgatctaaag cttcaatgtg gtccatgtca acagataagc tttgagcttt
    35041 tcggaggcct tccactagac ttgccatttc cttgccgtac tggtaaatat ccaatttttc
    35101 aaaagatctt tcctgacgaa ttctataaag agcaatcaac tttgtgacat aacgctgaaa
    35161 atcatttgaa gtcttccatg cttttaggaa gcttttagga tcctcaatgg ctaaactaat
    35221 catcacataa gcccaagctt ggtggtgatc actaaaggta aagttatctt tcaaagaaac
    35281 tatcagatga ttcaagcctg cttcctgctg cttcaagcct ggtaaatagt cataagcctg
    35341 acaagcaatc atggcagaaa tcccttttcg ccagtgcggt gccatcaata atttatcaaa
    35401 ttcagtaaaa gaacgttcca cagaaatctt ttccaataga ggtgaatggc tcctcatagc
    35461 ttcaaaagtt gcagcttcaa tgtcaaaatc cagactcgcc gcaaatcgaa agcctctcat
    35521 aatgcgtagt gcatcttctt caaaacgttc ctctgcttta cccactgctc gtaaccgttt
    35581 ttgctccaaa tcaatgagtc ctctaaattt atcaataact tgaccatttt catccaaggc
    35641 caaggcattg acggtaaagt ctcttcgttt taagtcttcc tctaaagagc gcacaaaaga
    35701 aacctgacta ggacggcgat agtcaacata gacatcttct gtcctaaagg ttgtgatttc
    35761 atactcaccg ccattttcaa gcacgagcac tgtaccatgt tcaatgccaa catcgacagt
    35821 tctgttaaaa atcgctttag tctcttcagg ataggaacta gttgcaatat ctacatcatg
    35881 aatgggacgc tcgagtaaaa catctctgac gcttcctccc acaaagtagg cttcataacc
    35941 agcttctttt attttagtca atatgggtaa agccttctga aactcagaag gcattgtcat
    36001 taatttcata cgttgttttc taacctatca tccaagtagc ccaatctaaa gtgtgattag
    36061 gctacttggg ttctatcaca ttttgttatt gttttagtga ttcttgcaat taactatttt
    36121 ttctaatcga caattaaagc ctcggtgtta cgccaaatgc aatggctcct tctcctaaat
    36181 gagtagcaat caccgctcca aaatgaacct cttcaatgtc atattgataa ccactgtctt
    36241 gtaagagtcg tttcaaataa tcagctttgt cttgtgcttt tgagtgaata atagacacat
    36301 tatactgacc gtctgctatc aagtcattta aaatctcaac caagcgtttc atggctttct
    36361 tttctgttct cactttttca taaacaacga tttttccctc ttcatcaaag cgtaagatag
    36421 gtttaatact caaaagattt ccaagaagag cagacccatt tgacaggcgt ccgcctttaa
    36481 ccagatgatt aaggtcatca accataataa aggctgtcgt cccatcaatc tgttcttgca
    36541 gcttgtttaa aatagcttga aatgtcattc cttgacgtga ccaatctagc acatttttta
    36601 ccatactacc taaaggagca gatgtgatct tactgtctgg aaatgccatt tcaatctcag
    36661 gatgttcttc agctaaaaat tgaatatttt gccaaaagcc tgagattcct ccagctaaga
    36721 acaagccaat aacatgtgta tagcccttag aagacaaaag tcctaaaaga ttatctagtt
    36781 cagataaact tggctgactt gtcttgggaa gattttggga gtcagccatc ttttgataaa
    36841 aatcatctat actcaaattt cgaccttcaa aataggtctc atcgtcaatg ataactggta
    36901 tatcaaggct aaaaatagct ttatcttgtt tcagatctgt tggtagtgtt gctgtactgt
    36961 cagtaattac tgctaatttc attaattttt aaactccaaa tgaatacctg gacgatccaa
    37021 ggcaatttct gtgacttcat aagtcaatcg cttaaccatg tctagcaaag gagcagctaa
    37081 ggattcaact tcctcttgcg taaattcgct tggtttatcc actaaacgat ctaaaatacg
    37141 aaccatttgt gagatgaccc cactaataac aaattcttct ttgacaataa caaattgcaa
    37201 tacagataca attactgttt ctttttgctg ctcatcttta tcaatcaact gaaaagtcac
    37261 ttcaaaattg gtctctggtg ttccgttttc tttttcccac tctaaatttc tagcatcata
    37321 atggtactgg ttgacaaatt ctttttcacg aactaattgc attttttatt ctccttggta
    37381 tcaatatgat ccattatagc atagatttga agattattaa agtagcccct aaactactat
    37441 tttcgcataa cgttttaaac agtgctatct ctcgaacaga tatctatttt ttcacctatt
    37501 tatatttagt cgtccttata ctgacattat atcaaaaaaa cacccgttag tggtcttgta
    37561 ctgcacctca attaaaacag aaccactggt caggtaagtt ttaagtccag gataaaaagg
    37621 tttatcacca aggcctcatc atgcttagcc aagtatttcg aactagcttg tcttagctct
    37681 aatcgctcaa acgtaaatcc taggcgttca atccgccgca aaacctctcc aactaaccca
    37741 tacttaaacc catagagctt aatcatcgct ccgcccttct tctcctttta tccattataa
    37801 aataaaaacg ttttaacaga caaaaaatag gaaagtacca gactattgga tttatttttt
    37861 tatctcaaaa tccattaacg atgttgagtt aaaggcattc aaaacaacat agatcgtaag
    37921 ctaacaagat tttttatcaa ttgaacctat cgtccccagt tataccacga cctcttctgg
    37981 atgaggtctt ttttttattt gtctaatttc atcaacgctt cttcctctct ttcttctatc
    38041 acagctctcc tattgctcac ttcctcatgc ggcaacatat catcaaaaaa ccgtccattt
    38101 taagcacaac cactactgta tctcttgtga tatctccatt gtcaatcgct tgtttacgtt
    38161 tattaaaaat tatttaaaaa attaagtatt attttaaaaa attgcaacaa tagatgtcta
    38221 tatgttataa tctttttata ataaaattat atagaaaaag gtattcttat gagaaaaaga
    38281 tgctattcaa cttcagctgc agtattggca gcagtgactt tatttgctct atcggtagat
    38341 cgtggtgtta tagcagatag tttttctgct aatcaagaga ttatatattc ggaagtaaca
    38401 ccttatcacg ttacttccgt ttggaccaaa ggagttattc ctccagcaaa cttcactcaa
    38461 ggcgaagatg tttttcacgc tccttatgtt gctaaccaag gatggtatga tattaccaaa
    38521 acattcaatg gaaaagacga ccttctttgc ggggctgcca cagcagggaa tatgcttcac
    38581 tggtggttcg atcaaaacaa cgaaaaaatt gaagcatatc taaaaaaaca cccagataaa
    38641 caaaaaatca tgtttggtga tcaagaatta ttggatgtaa gaaaagttat taatactaaa
    38701 ggtgaccaaa caaatagcga gctttttaat tatttccgag ataaagcttt ccccggtttg
    38761 tcagcacgcc gaattggagt tatgcctgat cttgttttag atatgtttat caatggttat
    38821 tacttaaatg tttataagac acagactact gatgtcaata gaacctatca agagaaagat
    38881 cgccgaggtg gtatttttga cgccgtattt acaagaggtg atcaaagtaa gctattgaca
    38941 agtcgtcatg attttaaaga aaaaaatctc aaagaaatca gtgatctcat taagaaagag
    39001 ttaaccgaag gcaaggctct aggcctatca cacacctacg ctaacgtacg catcaaccat
    39061 gttataaacc tgtggggagc tgacttcgat tctaacggga accttaaagc tatttatgta
    39121 acagactctg atagtaatgc atctattggt atgaagaaat actttgttgg tgttaattcc
    39181 tctggaaaag tagctatttc tgctaaagaa ataaaagaag ataatattgg tgctcaagta
    39241 ctagggttat ttacactttc aacagggcaa gatagttgga atcagaccaa ttaaagcgta
    39301 tcaataagaa agaatacctt caacagatga tggtattcta aggactaata ctattgcagg
    39361 gaattttttt atagatgggc aacagcaaaa aacattaata aatcctataa aaatcgataa
    39421 ggatattgtt acgattcaag agttcgattt taaaataaga aaatttttga tggaatcaaa
    39481 agaaattcat ttgactaagt ctccttatat aagggggagt ttagaaattc acagtaaaaa
    39541 taggaaacat gaaaaaatcg atttatatga cgcaaaaccc aatagcacca gatctgatgt
    39601 ctttaaaaaa tataaagaca ataagactat aaacatgaaa gatttcagcc attttgatat
    39661 ttatctttgg actaaataag ctaaaagctt tggataaata tgatcaattg acctataata
    39721 acattgatac caaatctaaa actgctcaga ttgaattgcg ccccaaaagt tagacaaaaa
    39781 atctaataat tggggtgttt ttgtctggca ttaagtttag ctaataacct tgcttaaatc
    39841 acattaaacc aataatggaa aaagacatct ccaaataaat gctatgatgg aactatatga
    39901 tagagtgatc aaggttggca atatcaacac aactattatc atcatttcct aaactctaaa
    39961 ggaattcgtc cgtctatgtc acgtaaaaga aacagtccta acaatagcat gatggaatct
    40021 ttctttggca tcttaaagtc agaaatgttc tatggttatg agaataacta taaatcacta
    40081 gaagacttag aacaagcgat tacaaatgac attgattatt acaacgataa acatatcaaa
    40141 gtaaaactaa aaggatttag ttctgtacaa tacagaacta aatcctttac ttaaaataga
    40201 gtatccagct tttttggggt cagtgcaagc agattgttgt tagtgttaca ttaataagtc
    40261 atgcgtttag cccaagcctc atcaactgct agggtctccg catcagtgta attacgacga
    40321 tactcattcc aaacataacc cgaagttgct agaccagttt cttgagctga gctattagca
    40381 acatcataag ccgtcaaacc ataggttgca ataatattat ttagttttaa gttataactg
    40441 gtgtctgtag cgtataagcc agttagagct gctgtagcat cttgatacga tagcgtgttt
    40501 gattttctag cacctatata agtgctagaa cttagcaagt ctgcatagtc attaagggag
    40561 tctgcaatac ttggataagc tctaaaggct tgatcaatcg tataggtatt gccattacca
    40621 tcatcttccc aagttgacat cgtcacagaa gaaccgttat aggcaccctt aataccgaaa
    40681 aaattataat aaggtgcttg acttagactt gatttaccat tacttgattc taaaatcgct
    40741 tgtgctatca taacagacgc ataaagatca cgttcttgac caatagtact agcagttgga
    40801 ccaatttcat caataaaatg tcgggttgaa gaactggcga tagtctcagc tgacacgttt
    40861 gaagttttat gagattgtct cattgcacta taagctccta aacaagctgc tagaacaaaa
    40921 agactgataa gtacaagctt acctttcttt tttgtcatta ttcacatatc cttttttata
    40981 cattttctat gtttctatta tagcacacga acgtttaaat taacttttcc acagataatt
    41041 taatgagatt gataactttt gtcttgaaat cgacatattt cttctgattt tttttaaaat
    41101 tgtggataac tatttcatta gaccatcaaa attagtgagt tgataccatt caatcaattc
    41161 atttaatttg gtatgg
//
