LOCUS       NZ_CP035435            41176 bp    DNA     circular CON 13-OCT-2024
DEFINITION  Streptococcus pyogenes strain emm64.3 chromosome, complete genome.
ACCESSION   NZ_CP035435
VERSION     NZ_CP035435.1
KEYWORDS    RefSeq.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1779766)
  AUTHORS   Davies,M.R., McIntyre,L., Mutreja,A., Lacey,J.A., Lees,J.A.,
            Towers,R.J., Duchene,S., Smeesters,P.R., Frost,H.R., Price,D.J.,
            Holden,M.T.G., David,S., Giffard,P.M., Worthing,K.A., Seale,A.C.,
            Berkley,J.A., Harris,S.R., Rivera-Hernandez,T., Berking,O.,
            Cork,A.J., Torres,R.S.L.A., Lithgow,T., Strugnell,R.A., Bergmann,R.,
            Nitsche-Schmitz,P., Chhatwal,G.S., Bentley,S.D., Fraser,J.D.,
            Moreland,N.J., Carapetis,J.R., Steer,A.C., Parkhill,J., Saul,A.,
            Williamson,D.A., Currie,B.J., Tong,S.Y., Dougan,G. and Walker,M.J.
  TITLE     Atlas of group A streptococcal vaccine candidates compiled using
            large scale comparative genomics
  JOURNAL   Nat. Genet. (2019) In press
REFERENCE   2  (bases 1 to 1779766)
  AUTHORS   Davies,M.R., McIntyre,L., Mutreja,A., Lacey,J.A., Lees,J.A.,
            Towers,R.J., Duchene,S., Smeesters,P.R., Frost,H.R., Price,D.J.,
            Holden,M.T.G., David,S., Giffard,P.M., Worthing,K.A., Seale,A.C.,
            Berkley,J.A., Harris,S.R., Rivera-Hernandez,T., Berking,O.,
            Cork,A.J., Torres,R.S.L.A., Lithgow,T., Strugnell,R.A., Bergmann,R.,
            Nitsche-Schmitz,P., Chhatwal,G.S., Bentley,S.D., Fraser,J.D.,
            Moreland,N.J., Carapetis,J.R., Steer,A.C., Parkhill,J., Saul,A.,
            Williamson,D.A., Currie,B.J., Tong,S.Y., Dougan,G. and Walker,M.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2019) Department of Microbiology and Immunology,
            University of Melbourne, The Doherty Institute of Infection and
            Immunology, Melbourne, Victoria 3000, Australia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 80x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_005161325.1-RS_2024_10_12
            Annotation Date                   :: 10/12/2024 01:25:26
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,787
            CDSs (total)                      :: 1,698
            Genes (coding)                    :: 1,645
            CDSs (with protein)               :: 1,645
            Genes (RNA)                       :: 89
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 27 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 13 of 53
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:28:24
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1074618
            Orig. end                         :: 1115794
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP035435.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..41176
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="T3PKS"
                     /region_number="2"
                     /rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /tool="antismash"
     cand_cluster    1..41176
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /kind="single"
                     /product="T3PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..41176
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:21176](+)"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..21176
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
     gene            complement(783..1433)
                     /locus_tag="ETT64_RS05670"
                     /old_locus_tag="ETT64_05670"
     CDS             complement(783..1433)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057640.1"
                     /locus_tag="ETT64_RS05670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT64_05670"
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_011888969.1"
                     /transl_table=11
                     /translation="MINIPLMKDSLGFVLSGLPYTLGISLLSFFTGLFLGLGLSLLGRS
                     RQPLIHYLVRAYISIMRGVPMIVVLFVLYFGLPYYGLELPALLCAYLGFSMVSAAYISE
                     VFRSSIEAIDKGQWEAAKALGLPYALMVKKIILPQAFRIAVPPLGNVIIDMVKSSSLAA
                     MITVPDIFQNAKIIGGREWDYMSMYILVAFIYWLIAFLLERYQEFLENKLALV"
     gene            complement(1462..2325)
                     /locus_tag="ETT64_RS05675"
                     /old_locus_tag="ETT64_05675"
     CDS             complement(1462..2325)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061079.1"
                     /locus_tag="ETT64_RS05675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT64_05675"
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="WP_012560627.1"
                     /transl_table=11
                     /translation="MKKSVTLLSIGLASLLLAACAPHKSQKSSWDTIKEKGVLKVATPG
                     TYQPTSFYNDNNELVGYEVDMVKEIGKRLNIKVKFVETGFDQAFTSVDSGRVDISLNNF
                     DITPKRQKKYNISTPYKYGVGGMIVRADGSSNMVKKDLSDWKGKKAAGASGTEYMKVAQ
                     KQGAELVTYDNVTGDVYLNDVANGRTDFIPNDYPAQKLFVDYMLSQNPNLNVKMSDVQY
                     NPTEQGIVMNKKDDSLKKKIDAVIKDMIKDGSLKKISETYYAGQDLTKPFGKDKKIPVI
                     DTKDVN"
     gene            complement(2443..3897)
                     /locus_tag="ETT64_RS05680"
                     /old_locus_tag="ETT64_05680"
     CDS             complement(2443..3897)
                     /EC_number="3.5.1.4"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1105: amidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407508.1"
                     /locus_tag="ETT64_RS05680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT64_05680"
                     /product="amidase"
                     /protein_id="WP_032464962.1"
                     /transl_table=11
                     /translation="MTYQDATAMAIAVQTGQTTPLELVTQAIYKAKKLNPTLNAITSER
                     FEAALEEAKQRDFSGKPFAGVPIFLKDLGQELKGDLSTSGSKLFKNHHATKTDLFVKRL
                     EDLGFIILGRSNTPEFGFKNISDSQLHGPVSLPHDKTRNAGGSSGGAAALVSSGISALA
                     PASDGGGSIRIPASFNGLIGLKPSRGRIPVGPGSYRSWQGASVHFALTKSVSDTRNLLY
                     YLQMEQMESPFPLATLTKDSIYQSLQRPLTIAFYQRLSDGSPVSLDTAKALKQAVTWLR
                     EQGHQLVELEEFPVNMTEVIRHYYIMNSVETAAMFADIEDTFGRPMTKDDMETMTWAIY
                     QSGKDIPAWRYSQVLQKWDTYSATMASFHETYDLLLTFTTNTPAPKHGELVPDSKLMAN
                     LAQAEIFSSEEQFNLVETMFGKSLAINPYTALPNLTGQPAISLPTYETKEGLPMGIQLI
                     AAKGREDLLLGIAEQFEAAGLLKIPQ"
     gene            complement(4094..4723)
                     /gene="pyrE"
                     /locus_tag="ETT64_RS05685"
                     /old_locus_tag="ETT64_05685"
     CDS             complement(4094..4723)
                     /EC_number="2.4.2.10"
                     /GO_function="GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pyrE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922180.1"
                     /locus_tag="ETT64_RS05685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT64_05685"
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="WP_002984920.1"
                     /transl_table=11
                     /translation="MTLASQIATQLLDIKAVYLKPEDPFTWASGIKSPIYTDNRVTLSY
                     PKTRDLIENGFVETIRAHFPEVEVIAGTATAGIPHGAIIADKMTLPFAYIRSKPKDHGA
                     GNQIEGRVLKGQKMVIIEDLISTGGSVLDAAAAASREGADVLGVVAIFTYELPKASQNF
                     KEAGIKLITLSNYTELIAVAKLQGYITNDGLHLLKKFKEDQVNWQQ"
     gene            complement(4781..5473)
                     /gene="pyrF"
                     /locus_tag="ETT64_RS05690"
                     /old_locus_tag="ETT64_05690"
     CDS             complement(4781..5473)
                     /EC_number="4.1.1.23"
                     /GO_function="GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA]"
                     /GO_process="GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="pyrF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984921.1"
                     /locus_tag="ETT64_RS05690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT64_05690"
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="WP_011184421.1"
                     /transl_table=11
                     /translation="MKEERPIIALDFSSFEETKAFLDLFPAEEKLYVKIGMELYYAQGP
                     DIVRYIKSLGHNVFLDLKLHDIPNTVRAAMAVLKELDIDMATVHAAGGVEMLKAAREGL
                     GQGPTLIAVTQLTSTSEDQMRGDQNIQTSLLESVLHYSKGAAKAQLDGVVCSAQEVEAI
                     KAVTPTGFTCLTPGIRPKGSNIGDQKRVMTPNQARRIGSDYIVVGRPITQAKDPVAAYQ
                     AIKAEWAG"
     gene            complement(5750..6286)
                     /locus_tag="ETT64_RS05695"
                     /old_locus_tag="ETT64_05695"
     CDS             complement(5750..6286)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990141.1"
                     /locus_tag="ETT64_RS05695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT64_05695"
                     /product="hypothetical protein"
                     /protein_id="WP_020905099.1"
                     /transl_table=11
                     /translation="MNVTEQNSHQILIQKLLVSIHYLTLFRDELKLVERTPSILGGEFP
                     AHLVQSELGDIVAAIDTLDMQQRLIESTFWYEESAFKLMNKTLDIVDNWIKGVDHLIDL
                     CQSKEVFQIIIGDKRIRVFGVLSDVFSSLKVSALSLKEAPIPDVLYEHIQRVNLEEEAF
                     IKYYQSPKIPTGEFE"
     gene            6508..7413
                     /locus_tag="ETT64_RS05700"
                     /old_locus_tag="ETT64_05700"
     CDS             6508..7413
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284709.1"
                     /locus_tag="ETT64_RS05700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT64_05700"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_136292940.1"
                     /transl_table=11
                     /translation="MRIQQLHYIIKIVECGSMNEAAKQLFITQPSLSNAVKDLEMEMGI
                     TIFNRNPKGITLTKDGVEFLSYARQIIEQTSLLEDRYKNHNTGRELFSVSSQHYAFVVN
                     AFVSLLKRTDMTRYELFLRETRTWEIIDDVKNFRSEIGVLFINDYNRDVLTKLFDDNHL
                     TASPLFKAQPHIFVSKSNPLATKSLLSMDDLSDFPYLSYDQGIHNSFYFSEEMMSQMPH
                     NKSIVVSDRATLFNLMIGLDGYTVASGILNSNLNGDQIVTIPLDVPDEIDIVFIKHEKA
                     NLSKMGERFIEYLLEEVTFD"
     gene            complement(7493..8281)
                     /locus_tag="ETT64_RS05705"
                     /old_locus_tag="ETT64_05705"
     CDS             complement(7493..8281)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984926.1"
                     /locus_tag="ETT64_RS05705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT64_05705"
                     /product="LytR family transcriptional regulator"
                     /protein_id="WP_136292941.1"
                     /transl_table=11
                     /translation="MTNNQTLDILLDVYAYNHAFRIAKALPNIPKTALYLLEMLKERRE
                     LNLAFLAEHAAENRTIEDQYHCSLWLNQSLEDEQIANYILDLEVKVKNGAIIDFVRSVS
                     PILYRLFLRLITSEIPNFKAYIFDTKNDQYDTWHFQAMLESDHEVFKAYLSQKQSRNVT
                     TKSLADMLTLTSLPQEIKDLVFLLRHFEKAVRNPLAHLIKPFDEEELHRTTHFSSQAFL
                     ENIITLATFSGVIYRREPFYFNDMNAIIKKELSLWRQSIV"
     gene            complement(8274..8987)
                     /gene="deoD"
                     /locus_tag="ETT64_RS05710"
                     /old_locus_tag="ETT64_05710"
     CDS             complement(8274..8987)
                     /EC_number="2.4.2.1"
                     /GO_function="GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene="deoD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984928.1"
                     /locus_tag="ETT64_RS05710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT64_05710"
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="WP_002990147.1"
                     /transl_table=11
                     /translation="MSIHISAKKGDIADKILLPGDPLRAKFIAENFLEDAVCFNEVRNM
                     FGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKTLIRVGTAGAIDPEVHVRELV
                     LAQAAATNSNIIRNDFPEFDFPQIADFGLLDKAYHIAREMGVTTHVGNVLSSDVFYTNM
                     PERNMALGKLGVKAIEMEAAALYYLAAQHHVKALGIMTISDNLNDPTEDTTAEERQTTF
                     TDMMKVGLETLIAND"
     misc_feature    9359..9372
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.2"
                     /tool="antismash"
     gene            complement(9572..10381)
                     /locus_tag="ETT64_RS05715"
                     /old_locus_tag="ETT64_05715"
     CDS             complement(9572..10381)
                     /EC_number="2.4.2.1"
                     /GO_function="GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647060.1"
                     /locus_tag="ETT64_RS05715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT64_05715"
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="WP_003053715.1"
                     /transl_table=11
                     /translation="MSLMTKINETKDFLVAKGIEAPEFGLILGSGLGELAEEVENPVVI
                     DYADIPNWGKSTVVGHAGKLVYGDLAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKALG
                     CEGVLVTNAAGGIGYGPGTLMAITDHINMTGNNPLIGENLDEFGPRFPDMSDAYTKVYR
                     NKAHEVAEKMNIKLEDGVYMGLTGPTYETPAEIRAFKVLGADAVGMSTVPEVIVAAHSG
                     LKVLGISAITNFAAGFQSELNHEEVVEVTEHIKEDFKGLVKAILAEL"
     gene            complement(10365..10805)
                     /gene="arsC"
                     /locus_tag="ETT64_RS05720"
                     /old_locus_tag="ETT64_05720"
     CDS             complement(10365..10805)
                     /EC_number="1.20.4.1"
                     /GO_function="GO:0008794 - arsenate reductase
                     (glutaredoxin) activity [Evidence IEA]"
                     /GO_process="GO:0046685 - response to arsenic-containing
                     substance [Evidence IEA]"
                     /codon_start=1
                     /gene="arsC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922177.1"
                     /locus_tag="ETT64_RS05720"
                     /note="This arsenate reductase requires both glutathione
                     and glutaredoxin to convert arsenate to arsenite, after
                     which the efflux transporter formed by ArsA and ArsB can
                     extrude the arsenite from the cell, providing resistance.;
                     This arsenate reductase requires both glutathione and
                     glutaredoxin to convert arsenate to arsenite, after which
                     the efflux transporter formed by ArsA and ArsB can extrude
                     the arsenite from the cell, providing resistance; Derived
                     by automated computational analysis using gene prediction
                     method: Protein Homology."
                     /old_locus_tag="ETT64_05720"
                     /product="arsenate reductase (glutaredoxin)"
                     /protein_id="WP_032462953.1"
                     /transl_table=11
                     /translation="MEEITIYHNPNCGTSRNVLAMIRHAGIEPTIIEYLQTPPNRETLI
                     ELLQSMGISARELLRTNVPEFEAHGLANQAVAEKDIINAMLADPILINRPIVVTRKGVK
                     LCRPSETLLDILPVPLPSPYMKEDGESVNPIEVKGEKDVIDD"
     gene            complement(10821..12032)
                     /locus_tag="ETT64_RS05725"
                     /old_locus_tag="ETT64_05725"
     CDS             complement(10821..12032)
                     /EC_number="5.4.2.7"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008973 - phosphopentomutase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009117 - nucleotide metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184417.1"
                     /locus_tag="ETT64_RS05725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT64_05725"
                     /product="phosphopentomutase"
                     /protein_id="WP_020905095.1"
                     /transl_table=11
                     /translation="MSKFNRIHLVVLDSVGIGAAPDADKFFNAGVADTDSDTLGHISET
                     AGLSVPNMAKIGLGNISRPIPLKTVPTEDNPTGYVTKLEEVSLGKDTMTGHWEIMGLNI
                     TEPFDTFWNGFPEEILTKIEEFSGRKIIREANKPYSGTAVIDDFGPRQMETGELIVYTS
                     ADPVLQIAAHEDIIPVEELYKICEYARSITLERPALLGRIIARPYVGEPGNFTRTANRH
                     DYAVSPFQDTVLNKLADAGVPTYAVGKINDIFNGSGITNDMGHNKSNSHGIDTLIKTLQ
                     LPEFTKGFSFTNLVDFDANFGHRRDPEGYRDCLHEFDNRLPEIIANMKEDDLLLITADH
                     GNDPTYAGTDHTREYIPLLAYSASFTGNGLIPQGHFADISATVAENFGVDTAMIGESFL
                     GHLK"
     gene            complement(12109..12792)
                     /gene="rpiA"
                     /locus_tag="ETT64_RS05730"
                     /old_locus_tag="ETT64_05730"
     CDS             complement(12109..12792)
                     /EC_number="5.3.1.6"
                     /GO_function="GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /gene="rpiA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881270.1"
                     /locus_tag="ETT64_RS05730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT64_05730"
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="WP_009881270.1"
                     /transl_table=11
                     /translation="MEALKKIAGVTAAQYVTDGMTIGLGTGSTAYYFVEEIGRRVKQEG
                     LQVVGVTTSSVTSKQAEGLGIPLKSIDDIDSIDLTVDGADEVDKDFNGIKGGGAALLME
                     KIVATPTKEYIWVVDASKMVEHLGAFKLPVEVVQYGADRLFRVFEKAGYKPSFRMKGDS
                     RLVTDMQNYIIDLDLGCIKDPVAFGHLLDGTVGVVEHGLFNGMVDKVIVASKDGVTVLE
                     APKAG"
     misc_feature    complement(13026..13039)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 22.77"
                     /tool="antismash"
     gene            13170..15269
                     /locus_tag="ETT64_RS05735"
                     /old_locus_tag="ETT64_05735"
     CDS             13170..15269
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1223: ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922175.1"
                     /locus_tag="ETT64_RS05735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT64_05735"
                     /product="AAA family ATPase"
                     /protein_id="WP_136292942.1"
                     /transl_table=11
                     /translation="MTHFSGKDPFVNMDDIFNQLMANMGGYRSENPRYLVNGREITPEE
                     FQHYRQTGQLPVATTKATNSQMLTPKADSVLTQLGTNLTQEARQGHLDPVIGRNKEIQD
                     TAEILARRTKNNPVLVGDAGVGKTAVIEGLAQAIVNGDVPAAIKNKEIVSIDISSLEAG
                     TQYRGSFEETIQNLIQEVKEAGNIILFFDEIHQIVGAGATSSDSGSKGLADILKPALSR
                     GELTLIGATTQDEYRNTILKNAALARRFNEVKVNAPSAEDTFHILMCIRNLYEQHHHIT
                     LPDNVLKAAVDYSIQYIPQRSLPDKAIDLLDMTAAHLAAQHPVTDLKTLETEIAKQKES
                     QEKAVAKEDFEKALAAKTRIETLQKQIEQHNQSQNVTATVNDIAESVERLTGIPVSNMG
                     TNDLERLKGISSRLKSHVIGQDEAVAAVARAIRRNRAGFDDGNRPIGSFLFVGPTGVGK
                     TELAKQLALDLFGSKDAIIRLDMSEYNDRTAVSKLIGTTAGYVGYDDNNNTLTERVRRN
                     PYAIVLLDEIEKADPQIITLLLQVLDDGRLTDGQGNTINFKNTVIIATSNAGFGQQDTE
                     TSESNIMDRIAPYFRPEFLNRFNSIIKFNHLQKENLEEIVDLMLAEVNQTTAKKGISLT
                     IADDAKAHLIDLGYNHAMGARPLRRIIEQEIRDRITDYYLDHPEVKKLQAILKEGYLVI
                     RQNDQ"
     gene            complement(15327..16070)
                     /locus_tag="ETT64_RS05740"
                     /old_locus_tag="ETT64_05740"
     CDS             complement(15327..16070)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984942.1"
                     /locus_tag="ETT64_RS05740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT64_05740"
                     /product="hypothetical protein"
                     /protein_id="WP_002984942.1"
                     /transl_table=11
                     /translation="MTQVAQGRSKGKSLLCHQCNALFVFIIFLILLAVLFGVRYRNSSI
                     EGIWRTTSIDQKLGDDFAKRLTGLHQSPLIDDSLLTSSQMILTVKNNNVDLSFSVQVER
                     DIFVKRLAAYHQNELLKTLKENHLVVGDLSSKERQIIENSMPASHELEMILDQAFEKLA
                     SQIGGKYNQKTGHLSAVVLKGKVNRILHTIDIKEEVAAGHTSFSKGLLTPNGYFDYTRF
                     GKKLELLGDEKIIFKKALKKSPSSV"
     gene            complement(16218..16817)
                     /gene="yihA"
                     /locus_tag="ETT64_RS05745"
                     /old_locus_tag="ETT64_05745"
     CDS             complement(16218..16817)
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0043022 - ribosome binding [Evidence IEA]"
                     /GO_process="GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="yihA"
                     /gene_functions="other (smcogs) SMCOG1227: ribosome
                     biogenesis GTP-binding protein YsxC"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054379.1"
                     /locus_tag="ETT64_RS05745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT64_05745"
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="WP_038432912.1"
                     /transl_table=11
                     /translation="MAEEQVLNTHNASILLSAANKSHYPQDDLPEIALAGRSNVGKSSF
                     INTILGRKNLARTSSKPGKTQLLNFFNIDDKLRFVDVPGYGYAKVSKSERAKWGKMIEE
                     YLTTRDNLRAVVSLVDLRHAPSKEDIQMYDFLKYYDIPVIVVATKADKIPRGKWNKHES
                     VVKKALNFDNSDTFIVFSSVERIGIDDSWDAILEQV"
     gene            complement(16827..18056)
                     /gene="clpX"
                     /locus_tag="ETT64_RS05750"
                     /old_locus_tag="ETT64_05750"
     CDS             complement(16827..18056)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="clpX"
                     /gene_functions="other (smcogs) SMCOG1223: ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984948.1"
                     /locus_tag="ETT64_RS05750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT64_05750"
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="WP_002984948.1"
                     /transl_table=11
                     /translation="MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEI
                     IKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDRAKRALSVAVYNHYKRVSFTESRDD
                     DDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENILLK
                     LIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVP
                     PQGGRKHPNQEMIQIDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASY
                     MQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIQILTEPRNALVKQYQALLSYDG
                     VELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVE
                     GKSKPVLETA"
     gene            complement(18376..18873)
                     /locus_tag="ETT64_RS05760"
                     /old_locus_tag="ETT64_05760"
     CDS             complement(18376..18873)
                     /EC_number="1.5.1.3"
                     /GO_function="GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005542 - folic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984955.1"
                     /locus_tag="ETT64_RS05760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT64_05760"
                     /product="dihydrofolate reductase"
                     /protein_id="WP_002984955.1"
                     /transl_table=11
                     /translation="MTKEIIAIWAEDEAGLIGVAGKLPWYLPKELEHFKKTTLHQAILM
                     GRVTFEGMNCKRLPQRQTLVMTRNRDYQVDEVLTMTSIEKVLEWYHAQDKTLYIIGGNK
                     VLEAFNGYFDRIIKTVIHHRFKGDTYRPNLDFSHFTQESQTFYARDAKNPYDFTVTALK
                     HK"
     gene            complement(18953..19792)
                     /locus_tag="ETT64_RS05765"
                     /old_locus_tag="ETT64_05765"
     CDS             complement(18953..19792)
                     /EC_number="2.1.1.45"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /locus_tag="ETT64_RS05765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT64_05765"
                     /product="thymidylate synthase"
                     /protein_id="WP_011017679.1"
                     /transl_table=11
                     /translation="MTKADQIFKANIQKIINEGSLSEQARPKYKDGRTAHSKYITGAFA
                     EYDLAKGEFPITTLRPIPIKSAIKELFWIYQDQSNSLDVLEAKYNVHYWNEWEVDQTRT
                     IGQRYGAVVKKHDIISKILKQLAENPWNRRNVISLWDYEAFEETKGLLPCAFQIMFDVR
                     RVGEDLYLDASLTQRSNDILVAHHINAMQYVALQMMIAKHFGWKIGKFFYFVNNLHIYD
                     NQFDQAQELLKRQPVASQPKLVLNVPDGTNFFDIKPDDFELQNYDPVKPQLHFDLAI"
     misc_feature    complement(19748..19762)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 23.77"
                     /tool="antismash"
     gene            20001..21176
                     /locus_tag="ETT64_RS05770"
                     /old_locus_tag="ETT64_05770"
     CDS             20001..21176
                     /EC_number="2.3.3.10"
                     /GO_function="GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043: hydroxymethylglutaryl-CoA synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993959.1"
                     /locus_tag="ETT64_RS05770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT64_05770"
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="WP_023609855.1"
                     /sec_met_domain="Chal_sti_synt_N (E-value: 4.4e-07,
                     bitscore: 26.2, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIGIDKIGFATSQYVLKLEDLALARQVDPAKFSQGLLIESFSVA
                     PITEDIITLAASAADQILTDEDRSKIDMVILATESSTDQSKASAIYVHHLVGIQPFARS
                     FEVKQACYSATAALDYAKLHVASKPDSRVLVIASDIARYGVGSPGESTQGSGSIALLVT
                     ANPRILALNKDNVAQTRDIMDFWRPNYSFTPYVDGIYSTKQYLNCLETTWQAYQKRENL
                     QLSDFAAVCFHIPFPKLALKGLNNIMDNTVPPEHREKLIEAFQASITYSKQIGNIYTGS
                     LYLGLLSLLENSKVLQSGDKIGFFSYGSGAVSEFYSGQLVAGYDKMLMTNRQTLLDQRT
                     RLSVSKYEDLFYEQVQLDDNGNANFDIYLTGKFALTAIKEHRRIYHTNDKN"
     gene            21163..22440
                     /locus_tag="ETT64_RS05775"
                     /old_locus_tag="ETT64_05775"
     CDS             21163..22440
                     /EC_number="1.1.1.88"
                     /GO_function="GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA]"
                     /GO_function="GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1187: hydroxymethylglutaryl-CoA reductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880299.1"
                     /locus_tag="ETT64_RS05775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT64_05775"
                     /product="hydroxymethylglutaryl-CoA reductase, degradative"
                     /protein_id="WP_020833420.1"
                     /transl_table=11
                     /translation="MTKTNLNWSGFSKKTFEERLRLIEKFKLLNAENLNQLKTDVLLPI
                     QTANQMTENVLGRLALPFSIAPDFLVNGSTYQMPFVTEEPSVVAAASFAAKLIKRSGGF
                     KAQTLNRQMIGQIVLYDIDQIDNAKAAILHKTKKLIALANKAYPSIVKRGGGARTIHLE
                     EKGEFLIFYLTVDTQEAMGANMVNTMMEALVPDLTRLSKGHCLMAILSNYATESLVTTS
                     CEIPVRLLDHDKTKSLQLAQKIELASRLAQVDPYRATTHNKGIFNGIDAVVIATGNDWR
                     AIEAGAHAYASRNGSYQGLSQWHFDQDKQVLLGQMTLPMPIASKGGSIGLNPTVSIAHD
                     LLNQPDAKTLAQLIASVGLAQNFAALKALTSSGIQAGHMKLHAKSLALLAGATQDEIAP
                     LVNALLADKPINLEKAHFYLSQLRQS"
     gene            complement(22670..23659)
                     /gene="fni"
                     /locus_tag="ETT64_RS05780"
                     /old_locus_tag="ETT64_05780"
     CDS             complement(22670..23659)
                     /EC_number="5.3.3.2"
                     /GO_function="GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="fni"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984966.1"
                     /locus_tag="ETT64_RS05780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT64_05780"
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="WP_136292944.1"
                     /transl_table=11
                     /translation="MTNRKDDHIKYALKYQSPYNTFDDIELIHHSLPSYDLSDIDLSTH
                     FAGQDFDFPFYINAMTGGSQKGKAVNEKLAKVAAATGIVMVTGSYSAALKNPNDDSYRL
                     HEVADNLKLATNIGLDKPVALGQQTVQEMQPLFLQVHVNVMQELLMPEGERVFHTWKKH
                     LAEYASQIPVPVILKEVGFGMDVNSIKLAHDLGIQTFDISGRGGTSFAYIENQRGGDRS
                     YLNDWGQTTVQCLLNAQGLMDQVEILASGGVRHPLDMIKCFVLGARAVGLSRTVLELVE
                     KYPTERVIAIVNGWKEELKIIMCALDCKTIKELKGVDYLLYGRLQQVN"
     gene            complement(23646..24659)
                     /locus_tag="ETT64_RS05785"
                     /old_locus_tag="ETT64_05785"
     CDS             complement(23646..24659)
                     /EC_number="2.7.4.2"
                     /GO_function="GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016126 - sterol biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635411.1"
                     /locus_tag="ETT64_RS05785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT64_05785"
                     /product="phosphomevalonate kinase"
                     /protein_id="WP_002993953.1"
                     /transl_table=11
                     /translation="MSNYCVQTGGKLYLTGEYAILTPGQKALIHFIPLMMTAEISPAAH
                     IQLASDMFAHKAGMTPDASYALIQATVKTFADYLGQSIDQLEPFSLIITGKMERDGKKF
                     GIGSSGSVTLLTLKALSAYYQITLTPELLFKLAAYTLLKQGDNGSMGDIACIAYQTLVA
                     YTSFDREQVSNWLQTMPLKKLLVKDWGYHIQVIQPALPCDFLVGWTKIPAISRQMIQQV
                     TASITPAFLRTSYQLTQSAMVALQEGHKEELKKSLAGASHLLKELHPAIYHPKLVTLVA
                     ACQKQDAVAKSSGSGGGDCGIALAFNQNARDTLISKWQEADIALLYQERWGENDQP"
     gene            complement(24652..25596)
                     /gene="mvaD"
                     /locus_tag="ETT64_RS05790"
                     /old_locus_tag="ETT64_05790"
     CDS             complement(24652..25596)
                     /EC_number="4.1.1.33"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA]"
                     /GO_process="GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /gene="mvaD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888980.1"
                     /locus_tag="ETT64_RS05790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT64_05790"
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="WP_011284696.1"
                     /transl_table=11
                     /translation="MDPNVITVTSYANIAIIKYWGKENQAKMIPSTSSISLTLENMFTT
                     TSVSFLPDTATSDQFYINGVLQNDEEHTKISTIIDQFRQPGQAFVKMETQNNMPTAAGL
                     SSSSSGLSALVKACDQLFDTQLDQKALAQKAKFASGSSSRSFFGPVAAWDKDSGAIYKV
                     ETDLKMAMIMLVLNAAKKPISSREGMKLCRDTSTTFDEWVEQSAIDYQHMLTYLKTNNF
                     EKVGQLTEANALAMHATTKTANPPFSYLTKESYQAMEAVKELRQEGFACYFTMDAGPNV
                     KVLCLEKDLAQLAERLGKNYRIIVSKTKDLPDV"
     gene            complement(25578..26456)
                     /gene="mvk"
                     /locus_tag="ETT64_RS05795"
                     /old_locus_tag="ETT64_05795"
     CDS             complement(25578..26456)
                     /EC_number="2.7.1.36"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004496 - mevalonate kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016126 - sterol biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /gene="mvk"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054375.1"
                     /locus_tag="ETT64_RS05795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT64_05795"
                     /product="mevalonate kinase"
                     /protein_id="WP_002984974.1"
                     /transl_table=11
                     /translation="MNENIGYGKAHSKIILIGEHAVVYGYPAIALPLTDIEVVCHIFPA
                     DKPLVFDFYDTLSTAIYAALDYLQRLQEPIAYEIVSQVPQKRGMGSSAAVSIAAIRAVF
                     SYCQEPLSDDLLEILVNKAEIIAHTNPSGLDAKTCLSDHAIKFIRNIGFETIEIALNGY
                     LIIADTGIHGHTREAVNKVAQFEETNLPYLAKLGALTQALERAINQKNKVAIGQLMTQA
                     HSALKAIGVSISKADQLVEAALRAGALGAKMTGGGLGGCMIALADTKDMAEKISHRLKE
                     EGAVNTWIQML"
     gene            complement(26750..27982)
                     /locus_tag="ETT64_RS05800"
                     /old_locus_tag="ETT64_05800"
     CDS             complement(26750..27982)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888981.1"
                     /locus_tag="ETT64_RS05800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT64_05800"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_023609845.1"
                     /transl_table=11
                     /translation="MFNRIRIRFIMIASIAIFIILSSIVGIINTARCYQSQQEINRILH
                     LISSNKGKLPDTTESSKRLGTKLSEDSLSQFRYYSVIFNANGHLLSSNTANISALDGEE
                     AQYFARLFAKSGEEKGSYRHQDSVYSYLITQLPNEEKLVVILDTTFYFRSVGDLLAVSM
                     MLAFGGFIFFVVLVSLFSGMVIKPFVQNYEKQRRFITNAGHELKTPLAIISANNELVEL
                     MTGESEWTKSTSDQVKRLTGLINQMITLARLEEQPDVVLHMVDFSAIAQDAAEDFKSLV
                     LKDGKRFDLTIQPNIMIKAEEKSLFELVTILVDNANKYCDPKGLVKVSLTTIGRRRKRA
                     KLEVSNTYLEGKSIDYSRFFERFYREDESHNSKEKGYGIGLSMAESMVKLFKGTITVNY
                     KNDAIVFTVVI"
     gene            complement(27991..28659)
                     /locus_tag="ETT64_RS05805"
                     /old_locus_tag="ETT64_05805"
     CDS             complement(27991..28659)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984985.1"
                     /locus_tag="ETT64_RS05805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT64_05805"
                     /product="response regulator transcription factor"
                     /protein_id="WP_002984985.1"
                     /transl_table=11
                     /translation="MKILLAEDEWQMSNVLTTAMTHQGYDVDVVFNGQEAIDKAKDNAY
                     DIMILDIMMPIKSGIEALKEIRASGNCSHIIMLTAMAEINDRVTGLDAGADDYLTKPFS
                     LKELLARLRSMERRVESFTPQVLQFAGVTLNINEQELSAGNAIRLASKEGKLMAFLMLN
                     QGKYLDTKTLYQHVWSDQEDYDTSIVWVYISYLRQKLLAIQANVIIAGDKDTSYCLLEK
                     "
     gene            complement(28662..29312)
                     /locus_tag="ETT64_RS05810"
                     /old_locus_tag="ETT64_05810"
     CDS             complement(28662..29312)
                     /GO_process="GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984988.1"
                     /locus_tag="ETT64_RS05810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT64_05810"
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="WP_002984988.1"
                     /transl_table=11
                     /translation="MKERLEHYSTSSIYSGFEVYLPLVLQTITDVIIAENIKSKKETGF
                     KLYEHFTSRIKSEASMIEKCQRKQLPLTSKSALKIIKDSIGIRIICGFIDDIYRMVDLL
                     KSIPGMSVNTEKDYILNAKPNGYRSYHLILELETHFPDILGEKKGCYFIEVQLRTIAQD
                     SWASLEHQMKYKHQVANAEMITRELKRCADELASCDVTMQTIRQLIQETTEEE"
     misc_feature    29448..29461
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.6"
                     /tool="antismash"
     misc_feature    29527..29540
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.3"
                     /tool="antismash"
     misc_feature    complement(29528..29541)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.93"
                     /tool="antismash"
     gene            29532..31544
                     /locus_tag="ETT64_RS05815"
                     /old_locus_tag="ETT64_05815"
     CDS             29532..31544
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1283: 2`,3`-cyclic-nucleotide 2`-phosphodiesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888982.1"
                     /locus_tag="ETT64_RS05815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT64_05815"
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="WP_136292945.1"
                     /transl_table=11
                     /translation="MKKYFILKSSVLSILTSFTLLVTDVQADQVDVQFLGVNDFHGALD
                     NTGTAYTPSGKIPNAGTAAQLGAYMDDAEIDFKQANQDGTSIRVQAGDMVGASPANSAL
                     LQDEPTVKVFNKMKFEYGTLGNHEFDEGLDEFNRIMTGQAPDPESTINDITKQYEHEAS
                     HQTIVIANVIDKKTNDIPYGWKPYAIKDIAINDKIVKIGFIGVVTTEIPNLVLKQNYEH
                     YQFLDVAETIAKYAKELQEQHVHAIVVLAHVPATSKDGVVDHEMATVMEKVNQIYPEHS
                     IDIIFAGHNHQYTNGTIGKTRIVQALSQGKAYADVRGTLDTDTNDFIKTPSANVVAVAP
                     GIKTENSDIKAIINHANDIVKTVTERKIGTATNSSTISKTENIDKESPVGNLVTTAQLT
                     IAKKTFPTVDFAMTNNGGIRSDLVVKNDRTITWGAAQAVQPFGNILQVIQMTGQHIYDV
                     LNQQYDENQTYFLQMSGLTYTYTDNDPKNSDTPFKIVKVYKDNGEEINLTTTYTVVVND
                     FLYGGGDGFSAFKKAKLIGAINTDTEAFITYITNLEASGKTVNATIKGIKNYVTSNLES
                     STKVNSAGKHSIISKVFRNRDGNIVSSEVISDLLTSTENTNNSLGKKETTTNKNTISSS
                     TLPITGDNYKMSPIMTILALISLGGLNAFIKKRKS"
     misc_feature    complement(29543..29556)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.33"
                     /tool="antismash"
     gene            complement(31626..32036)
                     /locus_tag="ETT64_RS05820"
                     /old_locus_tag="ETT64_05820"
     CDS             complement(31626..32036)
                     /EC_number="3.5.1.88"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017671.1"
                     /locus_tag="ETT64_RS05820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT64_05820"
                     /product="peptide deformylase"
                     /protein_id="WP_002984994.1"
                     /transl_table=11
                     /translation="MIREIITDHFLLQQKAQVAKKEDLWIGQDLQDTLAFYRQECLGMA
                     ANMIGEQKRIVIVSMGFIDLVMFNPVMVSKKGIYQTKESCLSLSGYRKTQRYDKITVEY
                     LDHNWRPKRLSLTGLTAQICQHELDHLEGILI"
     gene            complement(32292..32510)
                     /locus_tag="ETT64_RS09315"
                     /old_locus_tag="ETT64_05825"
     CDS             complement(32292..32510)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995561.1"
                     /locus_tag="ETT64_RS09315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT64_05825"
                     /product="hypothetical protein"
                     /protein_id="WP_011106820.1"
                     /transl_table=11
                     /translation="MALLFYYYVRKNQVKKLSQLKNLTEIFRKFIILTINNISAIKAFQ
                     TAGVLFGPVKAANARESSIWFENLTKQ"
     gene            <32753..>32830
                     /locus_tag="ETT64_RS09445"
                     /pseudo=""
     CDS             32753..>32830
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /locus_tag="ETT64_RS09445"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS3 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MDYCNNNRIKIKRKGLSPLQHRTKSF"
     gene            complement(32928..34805)
                     /locus_tag="ETT64_RS05835"
                     /old_locus_tag="ETT64_05835"
     CDS             complement(32928..34805)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922163.1"
                     /locus_tag="ETT64_RS05835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT64_05835"
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="WP_136284314.1"
                     /transl_table=11
                     /translation="MSHFLVEKLTKTVGDKTVFQDISFIIHDFDRIGIIGVNGTGKTTL
                     LDVLSGRLGFDGDHSPFSKANDYKIAYLTQDPEFNDAASVLDTVLSSDVKAIQLIRQYE
                     LLMANYTEDKQESLESLMSEMDRLDAWSIESDVKTVLSKLGITDLEQKVGDLSGGMRRR
                     VQLAQVLLGAADLLLLDEPTNHLDIDTIAWLTTYLKTAKKTVLFITHDRYFLDHVATRI
                     FELDKAGLTEYQGNYQDYVRLKAEQDERDAANLHKKKQLYKQELAWMRTQPQARATKQQ
                     ARINRFTDLKKEVHQDSSADKLEMAFETSRIGKKVIHFEDLSFAYGDRQLIKDFNLIIQ
                     NKDRIGIVGDNGVGKSTLLNIINGDLKPTSGKLDIGDTIRVGYFSQQLKDMDETKRVIN
                     YLQEVADEVKTSVGTTSISELLEQFLFPRSSHGTLIAKLSGGEKKRLYLLKLLIEKPNV
                     LLLDEPTNDLDIATLTVLENFLANFAGPVITVSHDRYFLDKVATKILAFEEGDIRIFYG
                     NYSDYLDEKAFEKETVEADLAKAIVTEEVPLPPKEEKKRMSYLEKQEWAQIEDKIATIE
                     ANIEEIENQMLTVVSDYGQLAQLQKELDQRNNDLLLAYERFEYLSGLDI"
     gene            complement(34802..36010)
                     /locus_tag="ETT64_RS05840"
                     /old_locus_tag="ETT64_05840"
     CDS             complement(34802..36010)
                     /EC_number="2.7.7.72"
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880307.1"
                     /locus_tag="ETT64_RS05840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT64_05840"
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="WP_186788940.1"
                     /transl_table=11
                     /translation="MKLMTMPSEFQKALPILTKIKEAGYEAYFVGGSVRDVLLERPIHD
                     VDIATSSYPEETKAIFNRTVDVGIEHGTVLVLENGGEYEITTFRTEDIYVDYRRPSQVS
                     FVRSLEEDLKRRDFTVNALALDENGQVIDKFRGLIDLKQKRLRAVGKAEERFEEDALRI
                     MRGFRFAASLDFDIEATTFEAMRSHSPLLEKISVERSFTEFDKLLMAPHWRKGISAMIA
                     CQAYDYLPGLKQQEAGLNHLIVSLKDNFTFSDHHQAWAYVMISLAIEDPKSFLKAWKTS
                     NDFQRYVTKLIALYRIRQERSFEKLDIYQYGKKMASLVEDLRKAQSLSVDMDHINTLDQ
                     ALVIHDKHDIVLNGSHLIKDFGMKPGPQLGLMLEKVELAIVEGRLDNDFTTIEAFVREE
                     LAT"
     gene            complement(36135..36983)
                     /locus_tag="ETT64_RS05845"
                     /old_locus_tag="ETT64_05845"
     CDS             complement(36135..36983)
                     /GO_function="GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985007.1"
                     /locus_tag="ETT64_RS05845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT64_05845"
                     /product="DegV family protein"
                     /protein_id="WP_002990194.1"
                     /transl_table=11
                     /translation="MKLAVITDSTATLPTDLKQDKAIFSLDIPVIIDDETYFEGRNLSI
                     DDFYQKMADSQNLPKTSQPSLSELDNLLGLLSSKGYTHVIGLFLAGGISGFWQNIQFLA
                     EEHPEIEMAFPDSKITSAPLGSMVKNVLDWSRQGMTFQAILNKLQEQIDGTTAFIMVDD
                     LNHLVKGGRLSNGSALLGNLLSIKPILRFDEEGKIVVYEKVRTEKKAMKRLVEILNDLI
                     ADGQYNVSIIHSKAQDKADYLKRLLQDSGYQYDIEEVHFGAVIATHLGEGAIAFGVTPR
                     L"
     gene            complement(36983..37363)
                     /locus_tag="ETT64_RS05850"
                     /old_locus_tag="ETT64_05850"
     CDS             complement(36983..37363)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985011.1"
                     /locus_tag="ETT64_RS05850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT64_05850"
                     /product="DUF1149 family protein"
                     /protein_id="WP_002985011.1"
                     /transl_table=11
                     /translation="MQLVREKEFVNQYHYDARNLEWEKENGTPETNFEVTFQLIDKDEQ
                     QKETVIVSVLQFVIVKEEFVISGVISQMVRILDRLVDKPSEFTQEEVESLAAPLLDMVK
                     RLTYEVTEIALDRPGIHLEFKN"
     gene            complement(<37566..37768)
                     /locus_tag="ETT64_RS05855"
                     /old_locus_tag="ETT64_05855"
                     /pseudo=""
     CDS             complement(<37566..37768)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051153.1"
                     /locus_tag="ETT64_RS05855"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="ETT64_05855"
                     /product="nucleoside-diphosphate kinase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MIKPYGFKYGLVGEVLRRIERLGFTFERLELRQASSKYLAKHDEA
                     LVINLFILDLKLT"
     gene            38270..39295
                     /locus_tag="ETT64_RS05860"
                     /old_locus_tag="ETT64_05860"
     CDS             38270..39295
                     /EC_number="3.4.22.-"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922160.1"
                     /locus_tag="ETT64_RS05860"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases.; This family includes IgM or IgG-cleaving
                     cysteine proteases.; This family includes IgM or
                     IgG-cleaving cysteine proteases.; This family includes IgM
                     or IgG-cleaving cysteine proteases; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="ETT64_05860"
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="WP_136292947.1"
                     /transl_table=11
                     /translation="MRKRCYSTSAAVLAAVTLFALSVDRGVIADSFSANQEIRYSEVTP
                     YHVTSVWTKGVIPPANFTQGEDVFHAPYVANQGWYDITKTFNGKDDLLCGAATAGNMLH
                     WWFDQNNEKIEAYLKKHPDKQKIMFGDQELLDVRKVINTKGDQTNSELFNYFRDKAFPG
                     LSARRIGVMPDLVLDMFINGYYLNVYKTQTTDVNRTYQEKDRRGGIFDAVFTRGDQSKL
                     LTSRHDFKEKNLKEISDLIKKELIEGKALGLSHTYANVRINHVINLWGADFDSNGNLKA
                     IYVTDSDSNASIGMKKYFVGVNSAGKVAISAKEIKEDNIGAQVLGLFTLSTGQDSWNQT
                     N"
     gene            39408..39680
                     /locus_tag="ETT64_RS05865"
                     /old_locus_tag="ETT64_05865"
     CDS             39408..39680
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014875.5"
                     /locus_tag="ETT64_RS05865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT64_05865"
                     /product="exotoxin beta-grasp domain-containing protein"
                     /protein_id="WP_390897282.1"
                     /transl_table=11
                     /translation="MKIDKDIVTIQEFDFKIRKFLMESKEIHLTKSPYVRGSLEIHSKN
                     RKHEKINLYDAKPNSTRSDVFKKYKDNKTINMKDFSHFDIYLWTK"
     gene            <39905..40195
                     /locus_tag="ETT64_RS05870"
                     /old_locus_tag="ETT64_05870"
                     /pseudo=""
     CDS             <39905..40195
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611514.1"
                     /locus_tag="ETT64_RS05870"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="ETT64_05870"
                     /product="IS3 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="SDQGWQYQHNYYHHFLNSKGIRPSMSRKRNSPDNSMMESFFGILK
                     SEMFYGYENNYKSLEDLE"
     gene            complement(40252..40959)
                     /locus_tag="ETT64_RS05875"
                     /old_locus_tag="ETT64_05875"
     CDS             complement(40252..40959)
                     /GO_function="GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990206.1"
                     /locus_tag="ETT64_RS05875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT64_05875"
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="WP_002990206.1"
                     /transl_table=11
                     /translation="MTKKKGKLVLISLFVLAACLGAYSAMRQSHKTSNVSAETIASSST
                     RHFIDEIGPTASTIGQERDLYASVMIAQAILESSNGKSSLSQAPYYNFFGIKGAYNGSS
                     VTMSTWEDDGNGNTYTIDQAFRAYPSIADSLNDYADLLSSSTYIGARKSNTLSYQDATA
                     ALTGLYATDTSYNLKLNNIIATYGLTAYDVANSSAQETGLATSGYVWNEYRRNYTDAET
                     LAVDEAWAKRMTY"
ORIGIN
        1 tttagccaat ctacgccagt catgccctct ttttctaaaa tagcgttggt tcttgaaaaa
       61 ggtttgctgc caaaaaagcc acgataagat gacaaagggc ttggatgagg gctctcgatg
      121 atgtggtgct ttggattagt aatgaaggct tttttcttcc ttgcataagc tccccacaaa
      181 atgaaaacta cagggctgtc tttctcattc agcactttaa taacagcgtc tgtaaatggc
      241 tcccatatta agcctgcatg cccattagcc tggcctgctg gcactgttaa gcaagcattc
      301 aaaagcagaa ccccttgact agcccaagtg cttaaatcat gatggtcacg aggaccaatg
      361 tcatctgcta attcttttaa aatattaata agggatggcg gagcagaaat ctcttctgga
      421 actgaaaatg ataagccctg ggcctgtttg gggccatgat aagggtcttg tcctaaaatc
      481 aacactttgg tttcttccaa aggagtgact tgtaaggctt taaagacatt ttctcgtgga
      541 ggatagacaa gaccggaagc ataggcttca tctaaaaagt gattgatgcg accgtagtaa
      601 tgctccggca aaaatgattt gattttctca tgccaaattg aatgagccat aagattcctt
      661 tctaatcacg tcagtttcta agttaaatac gatgtccttt tctatctagt ttaccacatt
      721 ttaaatagaa agaccctgaa aatatgatat ttccagggtt aatattcgtt ttttacagga
      781 tattaaacaa gtgctagctt attttctaag aattcttggt aacgttctaa caaaaaagca
      841 ataagccaat agataaaggc tactaaaata tacatggaca tgtaatccca ctctctaccg
      901 ccaataattt tggcattttg aaaaatatct ggtacggtaa tcatggcagc tagcgacgaa
      961 cttttaacca tatcaataat gacattgcct agaggaggaa ctgcaattcg aaaagcttga
     1021 ggaagaataa ttttcttaac cataagagca tatggcaacc ctaaagcctt agctgcttcc
     1081 cactgtccct tgtcaatagc ttctatagaa gagcgaaaaa cttcagaaat ataggcagcg
     1141 ctaaccatag aaaaaccaag ataagcgcaa agtaaagctg gcaattctaa accataataa
     1201 ggcaacccga aataaagaac aaagagcacc acgatcatcg gcacacctcg cataatagag
     1261 atgtacgctc taacaagata atgaatcaac ggctgacgtg accttcccag aagggatagg
     1321 cctaaaccta aaaacagacc cgtaaaaaaa ctgagcaacg aaataccaag ggtataaggt
     1381 aatcccgata acacaaatcc taaactatct ttcattaatg ggatattaat catgtggtta
     1441 ggactccttt aacatcaagt attagttaac gtctttcgta tcaatgacgg gaattttttt
     1501 gtctttgcca aaaggttttg tcagatcttg accagcatag taggtttcag agattttctt
     1561 caagctacca tcttttatca tgtctttaat aacagcatct atttttttct tgaggctatc
     1621 gtcttttttg ttcataacaa ttccttgttc ggttgggttg tactgaacat cgctcatttt
     1681 gacatttaga tttggatttt gagataacat gtaatccaca aataattttt gagctgggta
     1741 atcatttgga atgaaatctg ttcgaccgtt agccacatcg tttagataaa catctcctgt
     1801 aacattatcg taggtcacca gttcagctcc ctgtttttgc gctactttca tgtattctgt
     1861 tccagaagca ccagctgctt tttttccttt ccagtcgcta agatcttttt taaccatgtt
     1921 tgagctgcca tcagcacgga caatcatgcc tcctaccccg tatttataag gcgtagagat
     1981 attgtatttt ttctgacgtt ttggggtaat gtcaaagttg ttcaaagaaa tatccactcg
     2041 accactatca actgaggtaa acgcttggtc aaatcctgtt tcaacaaact tgactttaat
     2101 gttaagtcgt ttaccgattt ctttgaccat atctacttcg taacctacta actcattatt
     2161 atcgttgtaa aaagaagttg gctgataggt tcctggggta gctactttta acaccccttt
     2221 ttctttgata gtgtcccaac ttgatttttg agatttatgt ggcgcacatg ctgccaataa
     2281 aaggctggca agtccgatag acagtaaagt aactgatttc ttcatagtaa ctcctttatt
     2341 aagataagaa tagtataaca ttttgattaa gttgtgttat cagtgagcgc tcaatctctt
     2401 taaaaagtta atctataata gttaaactgt tttataagat tattattgag gaatcttcaa
     2461 taatcctgct gcctcaaact gctctgcaat tcctaataat aggtcctctc tacctttggc
     2521 tgcaattagt tgaatgccca ttgggagccc ttccttagtt tcgtaagtag gtaaactaat
     2581 agctggctgg ccagttagat taggcagagc tgtgtaagga ttaatagcca gactcttacc
     2641 aaacatggtt tcgaccaaat tgaattgctc ttcactgctg aaaatttcag cttgagccaa
     2701 gttagccatg agtttcgaat ctgggacaag ttctccgtgc ttaggagctg gtgtgttggt
     2761 tgtgaacgtc aacaacaggt cataagtctc atgaaaacta gccatggttg cactgtacgt
     2821 atcccatttt tgaaggacct gtgagtaacg ccaagctggg atgtctttac ctgattggta
     2881 aatagcccag gtcatggttt ccatatcgtc tttggtcatc ggacgtccaa aagtgtcttc
     2941 aatatcagca aacatagcag ctgtttccac actattcata atataataat gacgaatcac
     3001 ttctgtcata tttacaggaa actcttccaa ttcaactagc tgatgccctt gttctcttag
     3061 ccaagttact gcttgtttta aagcctttgc agtatctaaa gatactggac taccgtcact
     3121 taaccgttga taaaaagcaa ttgtcaaggg acgttgtagc gattgataaa tgctatcttt
     3181 tgttaaggtg gctaggggga aggggctttc catttgttcc atctgtaaat agtagagtag
     3241 atttctagta tcactaacag atttggtcaa ggcaaaatga actgaggctc cttgccagct
     3301 tcgataagaa ccaggtccga caggtatgcg tccacgacta ggtttgagcc caattaagcc
     3361 attaaacgaa gctggaatcc gaatagagcc acccccatca ctagctggtg ctagtgcact
     3421 aattccagat gacaccaaag ctgccgcacc acctgacgag ccaccagcat tgcgtgtttt
     3481 atcatgaggt aatgaaaccg ggccatggag ctgactatca ctaatatttt taaagccaaa
     3541 ttcaggtgtg ttagaacgcc ctaaaataat aaatcccaag tcttctaacc ttttcacgaa
     3601 taaatccgtt ttagttgcat gatgattctt gaatagctta gaacctgatg ttgataagtc
     3661 tcccttcaat tcttggccca aatctttcaa aaaaatggga actcctgcaa aaggcttacc
     3721 tgaaaaatcc ctttgtttgg cctcttctag agctgcttca aagcgttctg aggtaatagc
     3781 atttaaggta gggttcaact ttttagcctt ataaatagcc tgggttacta attctagtgg
     3841 tgtggtctga ccagtctgaa cagcaatagc catagccgtc gcatcttgat aagtcatagc
     3901 tactcttcct ttctaagata tgaatcctaa aacattcttt tttattaaaa cacaaataaa
     3961 agaaaaccac cattaaaagg ttagaaatta gaatgtgatg tgtaaggaat gtagacaaaa
     4021 caatcaaaac ataacatttg gaattggggc taaagagatt ttttcattaa aaataaacct
     4081 ggctgatagt tccttattgt tgccagttta cctggtcttc tttaaatttt ttaagtaaat
     4141 gtaaaccatc attagtaata tagccttgca actttgcaac tgcaattagc tcagtataat
     4201 tagaaagcgt aatcaacttg ataccagctt ctttaaaatt ctgactagct tttggtaact
     4261 cataagtgaa aatcgcaaca actcccagaa cgtcagctcc ctcacgactg gctgctgcgg
     4321 ctgcatctag taccgaacca cctgttgaaa tcaaatcttc aatgataacc attttttggc
     4381 ctttaagcac acgcccctca atctggttgc ctgctccatg atcttttggc ttactgcgaa
     4441 tataagcaaa aggaagagtc attttatctg ctataatggc accgtgagga atacctgctg
     4501 tagctgtacc agcgatgacc tcaacttctg ggaaatgagc cctgatagtt tccacaaacc
     4561 cattctcaat taaatcacga gtcttaggat aagaaagggt gacacgatta tcagtgtaaa
     4621 taggtgattt aatgccagat gcccacgtaa aagggtcttc aggctttaaa taaacagctt
     4681 taatatcaag taattgagtt gcaatttggc ttgctagtgt catttcttat tctccttttt
     4741 cttctttaac agacaagtgt tggtttccta atcttatctg ttagcctgcc cactcagctt
     4801 ttatggcttg gtaagcagcc actgggtctt ttgcctgggt aattggtcgc cctaccacaa
     4861 tataatcact tccaatacgt cttgcttggt ttggagtcat cactcgtttt tgatcgccaa
     4921 tattactgcc tttaggacga atgccaggag ttaagcaagt aaatcccgta ggcgtcaccg
     4981 ccttgatagc ttctacttct tgtgccgaac aaaccacccc atctagctga gctttagctg
     5041 cccccttgct gtaatgcaaa acagactcta aaagactcgt ttgaatattt tgatcaccac
     5101 gcatttggtc ttcactggtt gaagttagct gcgttaccgc aattaaggta gggccttgac
     5161 ctagtccttc tcgagctgct tttagcatct ctacaccacc agctgcatga acagttgcca
     5221 tatcaatatc taattcttta agaactgcca tagcagcacg aacagtattt ggaatatcat
     5281 gtaattttaa atccaaaaat acattatgcc ctaacgattt gatataccgg acaatatctg
     5341 gtccttgcgc ataatataat tccataccaa ttttcacgta tagtttttct tctgctggaa
     5401 ataagtctaa aaatgcttta gtctcctcaa atgatgaaaa gtctaaagca ataattgggc
     5461 gttcttcttt cataacttat cctttctata atgtgtcaat atctcattaa gcaccaaaaa
     5521 gcctcgctac caaagaagcg aggctacagc aaactaaaag ggaattccct ttttttatct
     5581 tgtatacctt gtttgcctct ctggactcac ttaaaggtgt ctaaatttaa actattatag
     5641 cttttttaaa acaagatgtc aaaacttttt gttatttgaa cacatttttc ctactatatc
     5701 tttttttgta tacttacgtc aactcatttt atcattttta cccaatcatt tattcaaact
     5761 cacctgtggg tatcttaggg ctttggtaat attttataaa agcttcttct tcaagattaa
     5821 ccctctggat atgttcatag agcacatccg gaataggagc ttccttaagt gacaaagcac
     5881 tcacttttaa agatgaaaaa acatcactta agaccccaaa aactcgaatg cgtttatctc
     5941 caataataat ttgaaagact tctttggact ggcataaatc tatcagatga tccactcctt
     6001 taatccaatt atcgacaata tccaaagttt tgttcatcaa cttaaaagct gattcttcat
     6061 accaaaaggt agactcaatc aagcgttgct gcatatccaa ggtatcaatg gccgcaacaa
     6121 tatctcccaa ctcagactgt actaaatgag ctggaaattc ccctccaagt atagaaggag
     6181 ttcgttctac aagcttcagt tcatctcgaa aaagagtcaa atagtggata ctgaccaata
     6241 acttttggat taagatttga tgactatttt gttcagtaac attcacacga ccaccaccct
     6301 ttgattagaa aaatacctat ttgttaatac tattaatata acacaagaaa aataaaaggg
     6361 caatgaaatt gatagattca actctcaaaa ttgaatcata tttatcctag gccatattga
     6421 gaaaagactc cagcgctttt tcaaagttct aaacccatga tgacgtttgt gcttgcgtct
     6481 ttattttttt tgagctagac tgtacttatg agaattcaac aactgcatta tattatcaaa
     6541 attgttgagt gcggctctat gaatgaagct gctaagcaat tatttatcac acaaccaagt
     6601 ctatccaatg cggtcaagga tttggaaatg gagatgggca ttaccatttt caaccgaaat
     6661 cctaaaggga tcaccttgac aaaagatggg gtggaatttt tatcttatgc tcgccaaatt
     6721 atagagcaaa catcactgtt agaagatcgc tataaaaacc acaatactgg ccgagagctc
     6781 tttagcgttt catctcaaca ttatgccttc gtagtcaatg catttgtctc actcctcaag
     6841 cggaccgaca tgactcggta tgaactcttt ttgcgcgaga caagaacttg ggaaatcatt
     6901 gatgatgtca aaaactttcg atctgaaatt ggtgttctct ttatcaacga ctataaccga
     6961 gatgtcttga ccaaattatt tgatgacaat catttgaccg cctctccatt atttaaggca
     7021 cagcctcata tttttgtcag caaatcaaat cctctagcaa ctaaaagcct attaagtatg
     7081 gacgacttga gcgattttcc ttacctgagc tatgaccaag ggattcacaa ctccttttat
     7141 ttttcagaag agatgatgtc ccagatgccc cacaacaaat caattgtggt cagtgaccgt
     7201 gccaccctct ttaacttaat gattggttta gatggctaca ccgttgccag tggtattcta
     7261 aatagcaatc taaatggtga ccagattgtg actatcccgc tagatgtccc tgacgaaatt
     7321 gacattgttt ttatcaagca tgaaaaagcc aacttgtcca aaatggggga acgttttatc
     7381 gaataccttc tcgaagaagt aacctttgat taatgtcttt ttcaatcgtc atactaaaaa
     7441 aacacggtag taagacctgt atcggtcaag ttatcgtgtt ttttgataaa tatcagacaa
     7501 tagattgtct ccaaaggctc aactcctttt taataatggc attcatgtca ttaaagtaaa
     7561 aaggctcacg tcggtagatt acaccagaaa aagtcgccaa ggtgataatg ttttccaaaa
     7621 aagcctgaga agaaaaatga gtggtgcgat gcagttcctc ttcatcaaaa ggcttaatca
     7681 aatgagccag aggattacgg acagcctttt caaaatgtcg taacaaaaaa accaagtcct
     7741 tgatttcctg aggtaaggag gtcaacgtca acatgtctgc taagcttttg gtcgtcacat
     7801 tgcgagactg cttttgagac aggtaagcct tgaaaacctc gtgatcagat tccaacatgg
     7861 cctgaaaatg ccaggtatca tattggtcat tctttgtatc aaaaatataa gccttgaagt
     7921 ttggaatttc tgacgtgatt agtctgagaa aaagtcggta aagaataggc gacactgacc
     7981 tgacgaaatc aataatagca ccgtttttta ctttaacttc taaatccaaa atgtaattgg
     8041 caatctgctc atcttcaagc gattggttaa gccataatga acagtggtac tggtcttcaa
     8101 tggtccgatt ctctgctgca tgttccgcca gaaaggcaag gttcaattct ctgcgctctt
     8161 ttaacatctc tagtaaatag agggcagttt tagggatatt tggcaaggct ttagcaattc
     8221 taaaggcgtg attataagca tagacatcca aaaggatgtc tagtgtttga ttattagtca
     8281 ttggcaatta aggtttccaa gccgaccttc atcatatcag tgaaagtggt ttggcgctct
     8341 tcagctgtag tatcttcggt tggatcattc aagttatctg agatcgtcat gattccaagg
     8401 gctttgacat ggtgctgagc agctaaatag taaagagctg ctgcttccat ttcgatggct
     8461 ttaacaccca atttaccaag agccatatta cgctcaggca tgttagtgta aaagacatca
     8521 gaagaaagca cattcccaac gtgagttgtt actcccattt ctctggcgat atggtaagcc
     8581 ttgtcaagta aaccaaaatc agcaatttgt gggaaatcaa attctggaaa gtcattacgg
     8641 ataatatttg agttggttgc tgctgcttgg gcaagcacca attcacgcac atgaacttct
     8701 gggtcaatcg cacccgcagt accaacacgg atcaatgttt tgacaccgta atcaacgatt
     8761 aattcacgag catagataga gatcgaaggc atccccatac cagttcccat gacagaaacg
     8821 cggtgccctt tgtaagttcc tgtgtagcca aacatgttac gcacttcgtt aaaacacact
     8881 gcatcttcta ggaaattttc agcgataaat ttcgcgcgca aagggtctcc aggtagaaga
     8941 attttatcag caatatcacc ttttttggca gaaatatgga tagacattat taagatatta
     9001 aaggcgacaa agaacaaagt aaaaatagga aactgacgac gcatcccaga tgctagacag
     9061 tttatctttt ttacacagtt ctccgcccgt attcaattca atgaatacag ttagccctac
     9121 ctttcctttt attttgtaga aggtcagagg gcggacagaa agcaactgaa atttagggaa
     9181 ctaacgccat gtgtgagcac aaaagttagt ttatctagtt tccgagcttt ccgcccgtat
     9241 tcaattgaat acaaccccat tcctttcata attgatattg aatagaagaa gagagctaaa
     9301 aatcgagttc aaataataaa ggactaactc tctttccttt attatttaaa aattaatacg
     9361 aagaaatgtt cgagtccatg cttaatttaa accgaatacg tctctttccc ttcgttggtt
     9421 atgttagtta gaaaagctag aatctgagtt caacattcat agaactcaca tcccgtgatt
     9481 attttttgat ttttttattg cgaacagatg tgccaaactg acgacataaa ataacattcc
     9541 tgtaataatg ctccagttga ttttgttcgt cctacaactc agctaaaata gctttaacaa
     9601 gacctttgaa atcttcttta atatgttcag tcacttcaac aacttcttcg tggttcaatt
     9661 ctgattggaa accagctgca aagttagtga tggctgaaat gccaagtact ttaagtccag
     9721 aatgagcagc cacaataact tctggcacag ttgacatgcc gacagcatct gctcctaata
     9781 ctttgaaagc acggatttct gctggtgtct cataagttgg accagttaag cccatataaa
     9841 caccatcttc tagtttgatg ttcatttttt cagccacttc atgtgcctta ttgcgataaa
     9901 ccttagtata ggcatcagac atatcaggaa agcgtggacc aaactcgtcc aagttttcac
     9961 cgattagtgg gttatttccg gtcatattga tatggtctgt gattgccatc aaggtacctg
    10021 ggccgtagcc gataccacca gctgcatttg tgacaagaac gccttcacat cccagagctt
    10081 tcatgacacg aacagggaaa gtcaccactt caagcgggtt tccttcgtaa aaatggaaac
    10141 gaccttgtag ggcaagtact ttacgaccag ctaaatcacc gtagactaat tttccagcat
    10201 ggcctacaac tgttgatttg ccccagtttg gaatatctgc ataatcaata acaacaggat
    10261 tctctacttc ttcagcaagt tcaccaagtc ctgaacccag aattaatcca aattctggag
    10321 cttcaattcc tttagcaact aaaaagtctt ttgtttcgtt aattttagtc atcaatgaca
    10381 tctttttctc cttttacctc aatagggttc acactctcgc catcctcttt catataagga
    10441 ctaggcaggg gaacaggaag aatatccagt aaggtctcag aaggacggca aagttttact
    10501 cctttgcgag tcacaacaat aggacgattg atcaaaattg gatccgccaa catggcatta
    10561 ataatgtctt tctcagctac tgcttgattt gctaatccat gagcctcaaa ttcaggaaca
    10621 ttggttcgca agagttctcg cgcagagatt cccatcgatt gtaagagctc aattaaagtc
    10681 tcccgattag gtggcgtctg caaatactca ataatagtag gctcaatacc tgcatggcga
    10741 atcatggcaa gaacattacg tgaagtgcca cagtttggat tatgataaat cgtgatttct
    10801 tccattatca actaattttc ttattttaag tgaccaagga atgactcccc aatcatggct
    10861 gtatcaactc caaaattttc tgcaacagtt gctgaaatat ccgcaaaatg cccctgtgga
    10921 ataagaccat ttccagtaaa ggatgcagag taggcaagca atggaatgta ttcacgagtg
    10981 tggtcggtac ctgcataggt tgggtcatta ccatggtcag cagtgatgag aagcaaatcg
    11041 tcttctttca tatttgcgat gatttcaggt aggcgattgt caaattcatg caagcagtcg
    11101 cgataaccct ctgggtcacg acgatgacca aagttggcat caaaatcaac aaggttagta
    11161 aaggagaatc ccttagtaaa ctcaggtaat tgaagagtct taataagcgt gtcaatacca
    11221 tggctgttcg acttattgtg tcccatgtcg tttgtaatac ctgaaccatt aaagatgtca
    11281 ttaatcttac caacggcata agttgggaca cctgcgtcag ccagtttgtt caaaacggta
    11341 tcttggaaag gagacactgc atagtcatga cggttagccg tacgtgtaaa gtttcctggt
    11401 tcgcctacat aaggacgcgc aataatacgg cctaaaaggg cagggcgttc aagcgtgatg
    11461 gagcgagcat attcacaaat cttgtaaagc tcttccacag gaataatgtc ttcatgggct
    11521 gcaatttgaa gcactgggtc tgctgaggtg taaacaatca actcacctgt ttccatttga
    11581 cgcggaccaa aatcatcaat aaccgctgtt cctgaatagg gtttattagc ttcacgaata
    11641 attttgcgac ctgagaattc ttcaatctta gttaaaatct cttctgggaa accattccag
    11701 aaagtgtcaa aaggttccgt aatgttcaag cccataattt cccaatggcc tgtcatggta
    11761 tcttttccaa gagatacttc ttccaatttg gtcacgtaac cagtaggatt atcttctgtt
    11821 ggaacagttt ttagtggtat tggacgagaa atgtttccaa gtccaatttt tgccatattt
    11881 ggaaccgata agcctgctgt ttctgaaata tgaccgaggg tgtcagaatc tgtatcagct
    11941 acaccagcat taaagaattt gtcagcatct ggtgctgcac caataccgac agagtctaaa
    12001 acaaccaagt gaatacgatt aaattttgac ataagtctcc aatctagggg aggttacggt
    12061 tgactcccca atacctataa aatatattaa cactgttata tgctaagact agcctgcttt
    12121 aggcgcttct aaaacagtaa cgccgtcttt actagcaaca atcaccttat caaccatacc
    12181 attaaagaga ccgtgttcca caacaccaac tgttccatct agcaggtgac caaaagcaac
    12241 aggatcttta atacaaccca aatcaagatc aataatatag ttttgcatgt ctgtcaccaa
    12301 acgactatca cctttcatac gaaaagacgg tttgtaacca gctttttcaa agacacggaa
    12361 caaacgatca gcaccgtatt gaacgacttc gactggtaac ttaaaggcac ccagatgctc
    12421 taccatttta gaagcatcaa caacccagat gtattctttt gttggtgttg caacaatttt
    12481 ttccattagt aaggctgcgc cgccaccctt gattccattg aaatccttat ccacttcatc
    12541 agcaccatct acggtgaggt caatgctatc aatatcatct atcgatttta aaggaatgcc
    12601 taagccttct gcttgcttgc tagtcacact tgacgtggtc acaccaacca cttgcagtcc
    12661 ttcttgcttt acgcgacggc caatttcctc aacaaaatag taagccgttg acccagttcc
    12721 aagcccaatg gtcatgccat cagtcacata ttgcgcagcg gtaacaccgg caattttttt
    12781 gagtgcttcc atgattcccc cttataatag aattgcgtct tagcacttta ttataccatg
    12841 aaagcgccaa cttgttaatg aaaacatttg tttttctctc attgacagcc taagtgctat
    12901 agaataggat gatcttttta aaacttatga tttattctaa agtcatcata taagcactta
    12961 cttttcgtgt ttatttagct ttttgaaaat caagtgtttt tgtttgacct ttactgacct
    13021 tttgattata ataatactat aagatgagta aaaataatgt ctgaatcatt ttattagcaa
    13081 agggtttcct atcatgtgaa atcctaacaa cgattctgcg actgcttaca aacatcttat
    13141 agtctatttt ttattgcgag gtaactgata tgacacattt ttctggtaaa gatccttttg
    13201 taaatatgga tgatattttc aaccaattaa tggcaaacat gggtggttat cgtagcgaaa
    13261 atccccgcta tctcgttaac ggtcgcgaaa taactcccga agaattccaa cactatcgtc
    13321 aaacaggaca actccctgta gcgacaacca aagcaacaaa ttctcaaatg ttaacaccta
    13381 aagctgatag tgtattgact caactcggaa ctaacttaac acaagaagct cgtcaagggc
    13441 atcttgaccc cgtcattggt cgtaacaaag aaattcaaga taccgctgaa atcttggcac
    13501 gacgaactaa aaataatcct gtccttgtcg gagatgctgg tgtcggtaaa actgcagtca
    13561 ttgaaggttt agctcaagcc attgttaatg gagatgtccc agccgctatt aaaaacaagg
    13621 aaatcgtatc aattgacatt tctagtcttg aagctggtac acagtatcgt ggttcctttg
    13681 aagagaccat tcaaaacttg attcaagaag taaaagaagc tgggaatatc atcttatttt
    13741 ttgatgaaat tcatcaaata gttggtgctg gtgccacaag cagtgattca ggctcaaagg
    13801 gacttgcaga tattcttaaa ccagccttgt cacgaggaga attaacactg attggtgcta
    13861 ctactcaaga cgaataccgc aatactattt taaaaaatgc tgctcttgct cgtcgcttta
    13921 atgaagttaa agtgaatgca ccatcagctg aagatacttt tcacatttta atgtgtattc
    13981 gtaatcttta tgaacaacac caccatatta cccttcctga taatgttcta aaagctgctg
    14041 ttgattattc tattcaatac atcccacagc gtagcctgcc agataaagca attgacttac
    14101 tggatatgac agctgctcat ttagctgcgc aacacccggt cactgactta aaaacactcg
    14161 aaactgaaat agctaaacaa aaagagagtc aagaaaaagc tgtcgccaaa gaagactttg
    14221 aaaaagcttt agcagcaaaa acacggattg aaacattaca aaagcaaatt gagcaacata
    14281 accaaagcca aaatgttact gctacagtca atgatatcgc agagtctgta gagcgcttaa
    14341 ctggtattcc cgtctctaac atggggacta atgatttaga aaggctcaaa ggaattagca
    14401 gccgcttaaa aagccatgtc atcggacaag atgaggctgt tgcagcagta gcacgtgcta
    14461 ttcgacgaaa tcgagcaggt tttgatgatg gtaaccgtcc aataggttct ttcctttttg
    14521 tgggtccaac tggtgttggt aaaacagagt tagctaaaca attagcactt gatttatttg
    14581 gttccaaaga tgctattatt cgacttgata tgtccgaata taacgatcgc actgctgtgt
    14641 caaaattgat tgggacaacg gctggttatg ttggctacga tgataataat aataccctaa
    14701 ctgagcgtgt tcgtcgtaac ccttatgcta ttgtcttact agatgaaatt gaaaaagctg
    14761 atcctcaaat cattacactt cttctacaag tgttagatga tggacgattg acagatggac
    14821 aaggaaatac tattaacttt aaaaataccg ttattattgc tacatcaaat gccggttttg
    14881 gccaacaaga tacggaaact tctgagtcta acattatgga tcgcattgca ccttatttca
    14941 gaccagagtt tttgaaccgt tttaatagta tcattaaatt taatcatctg caaaaagaaa
    15001 atttagaaga aattgttgat ttaatgctag ctgaagtaaa tcaaaccacc gcaaaaaaag
    15061 gtattagttt aacgattgct gatgacgcta aagctcattt gatagattta gggtacaatc
    15121 acgctatggg agctcgtcca ttacgacgta ttatcgaaca ggaaattcgt gaccgtataa
    15181 ctgattatta tcttgaccat ccagaagtca aaaaacttca ggcaatccta aaagaaggat
    15241 acctagtgat taggcaaaac gatcagtaat aaacttcttc aattgaataa ttttcaaaac
    15301 atgaaaaaat ccgtcttgtg actacgttat acacttgacg gacttttttt tagcgctttt
    15361 ttaaaaataa ttttttcatc gcctaataac tcaagtttct ttccaaatct ggtgtaatca
    15421 aaataaccat taggtgtgag caatcctttt gaaaaagaag tatgtcccgc tgctacttct
    15481 tctttgatat caatggtgtg caaaatacga ttaacttttc ctttgagaac aacagcagat
    15541 aaatgtcctg ttttttgatt atatttgcct ccgatctgag aagctaattt ctcaaaagct
    15601 tgatctaaaa tcatttctaa ttcatggcta gctggcatac tattctcaat aatttggcgt
    15661 tctttactac tcaagtcacc aacaactaaa tgattttcct ttaatgtctt taataattca
    15721 ttttggtgat aagcagctaa acgtttgaca aaaatgtctc gttcaacttg aacactaaaa
    15781 ctcaagtcaa cgttgttatt tttaactgtt agtatcatct gagatgacgt taataaacta
    15841 tcatcaataa gagggctctg atgcaaacca gtaagacgtt tagcaaaatc atcgcctaac
    15901 ttctgatcaa tgcttgttgt tcgccagata ccttcaatag agctattacg atatcgaaca
    15961 ccaaaaagta cagcaagcaa gataagaaaa ataataaata caaaaagggc attgcattga
    16021 tggcataaca atgactttcc tttagagcgc ccttgggcta cttgtgtcat gactcatctc
    16081 cttaatataa aatactagca tgtcatcatt aaggcgtcaa gtaaaatcgg taaacctaac
    16141 tatgattttt tatgttttcg ataagaaaaa caccctctac tgagaatgtt ttagcataga
    16201 taaatcaaca cctatcgcta gacctgctct aaaatagcat cccaagaatc atcgatacca
    16261 atacgttcta ccgaagaaaa tactataaaa gtatcagagt tgtcaaaatt caaagctttc
    16321 ttgaccacag actcatgttt gttccatttg ccacgaggaa tcttatctgc tttggttgcc
    16381 acaacaataa caggaatgtc atagtacttc aaaaagtcat acatctgaat atcttctttt
    16441 gaaggggcat gacgtaaatc aaccaaactc acgacagcac gcagattatc tctggtggtt
    16501 aagtattctt cgatcatctt tccccatttg gcccgttcac ttttagaaac cttggcatag
    16561 ccataaccag ggacatccac aaatctaagc ttgtcatcaa tattgaaaaa atttaatagt
    16621 tgggtttttc ctggcttgct tgaggttctt gccaaatttt tgcgccccaa tatggtatta
    16681 ataaaacttg atttaccaac atttgaacgt ccagcgaggg caatttctgg caaatcatct
    16741 tgggggtaat gagatttatt ggcagcgctc aataaaattg aggcgttatg ggtatttaag
    16801 acttgttctt cagccattat ttctccttaa gctgtctcta aaacgggttt tgacttgcct
    16861 tcgacagcag ccttggtgat acgcactttt gtgacatctt cttggcttgg aatttcaaac
    16921 atgatgtcta acatcgtttc ttcaataata gaacgaagac cacgtgctcc tgttttacgt
    16981 tcaatggctt tattggcaat ggcttctaag gcttccttat caaatgccaa ttcgacgcca
    17041 tcgtaagaaa gaagagcctg atattgcttg accagggcat ttcttggttc tgtcaaaatt
    17101 tgaatcaaat ctgatgtgtt tagttgttca agggctgcca caactggtaa gcggccaata
    17161 aattctggaa taagcccaaa cttttgaata tcttctgaaa taatttcttg catataagaa
    17221 gcattgtcat caattttacg gctgttttga ccaaaaccaa taactttttc acctaaacgt
    17281 tgtttaacga tctcctcgat gccatcaaaa gccccgccaa caataaacaa gatatttttt
    17341 gtatcaattt ggatcatttc ttgattaggg tgcttccgcc caccttgtgg gggaacactt
    17401 gctaccgtac cttcaataat tttaagaagg gcttgctgta caccttcacc agatacatca
    17461 cgtgtgatag atacgttctc acctttttta gcaatcttat ctatttcatc aacataaata
    17521 ataccacgct ctgctcgttc gacattatag tcagcagcct gaatcagttt gagtaaaata
    17581 ttttccacat cttctccaac ataccctgct tcagtcaaag aagttgcatc tgcaatagca
    17641 aatggtacat tgaggctttt agccagagtt tgtgctaaga aggtttttcc tgaacctgtt
    17701 ggtccaatca tcaaaatgtt ggacttttgt aaatccacat catcgtcatc acgactttct
    17761 gtaaacgaga cacgcttata atgattgtac acagcaactg ataaagcacg tttagcacga
    17821 tcttgaccaa ccacatattg atttaaaaca tcaagaagct cttttggttt tggaacttct
    17881 gtcaaatcgg caaggacttc ttcagccaat tcttctttta taatttcttg tgataaagct
    17941 acgcattcat tgcagatgaa aacattattt cctgcgataa tttttttaac gtcatcctgg
    18001 cttttaccac aaaatgaaca gtatacttta atatcgttag ttctacttcc tgccatttct
    18061 tataattctc ttactttctc ttatctttta ctgaatttta atattagtca atgtgttgta
    18121 ttggtttttg gtgattcttg cttgatagct aaatcttcac cagtgctgtc tttgcaagtc
    18181 acatctcaaa acaatgtacc atagaaggcg tgaatactat taaccagatt agtaaacgca
    18241 tttaataaga acagacttcc taagccataa cgattctttt taaaagctgg gatggcacaa
    18301 agaacacaaa tcacgcacaa aaaagccgta aatactccaa aaatactacg ttgcatcgct
    18361 tatcatctcc tcagactatt tgtgttttaa agcagtaacg gtaaaatcat aaggattttt
    18421 agcgtctcga gcatagaacg tttggctttc ttgcgtgaaa tgactaaaat ctagatttgg
    18481 tcggtaggta tctcctttaa aacgatgatg gataactgtt tttatgatac gatcgaaata
    18541 accattaaac gcttctaaaa ccttattccc accaatgata taaagtgttt tatcctgcgc
    18601 atggtaccac tccaagactt tttcaatact agtcattgtc aacacctcat ctacttgata
    18661 atctctattt cttgtcatga caagggtttg acgttgagga agtcttttgc aattcattcc
    18721 ttcaaaagtc acacggccca ttaagattgc ttgatgtagc gttgtctttt taaaatgttc
    18781 taactctttt ggtaaatacc atggtaactt acccgcaaca ccaataagcc ctgcttcatc
    18841 ctctgcccaa atagcaataa tttcctttgt cattaattat ttccttcatt ttaaactcta
    18901 tttattttac caaatttatg aacaaaatgc tcacaaaaaa tctaaataaa gtttaaatag
    18961 caaggtcaaa gtgcaactga ggcttcactg gatcataatt ttgtaattca aaatcatctg
    19021 gtttaatatc aaagaaatta gtcccatctg gaacatttaa aacaagctta ggctgactgg
    19081 caactggctg tcgttttagt aattcttgag cctgatcaaa ttggttgtca taaatatgta
    19141 aattgttaac aaaataaaag aacttaccta ttttccatcc aaaatgttta gcaatcatca
    19201 tctgcaaggc aacgtattgc atggcattga tgtgatgagc aactaatatg tcattagaac
    19261 gttgcgtcaa actagcatct aaataaagat cttcccctac acgtctaaca tcaaacatga
    19321 tttgaaaggc acatggcaac aacccttttg tctcctcaaa tgcttcatag tcccagagag
    19381 aaatgacatt acgacgattc caaggatttt ctgctaattg ctttagtatt tttgagatga
    19441 tatcatgttt tttgactaca gcaccataac gttgtccaat agtacgtgtc tggtcaactt
    19501 cccattcatt ccaataatga acattatatt tagcttctag cacatctaaa ctgttagact
    19561 gatcttgata tatccaaaat aattccttta tagcagattt aattggaatg ggtcgtaaag
    19621 ttgtgatggg aaactctcct ttagctaaat catattcagc aaacgcccca gtaatatact
    19681 tagaatgagc tgttcgacca tctttatatt taggacgtgc ttgctcactc aatgatcctt
    19741 cgtttataat tttttgaata ttagctttaa aaatctggtc agcttttgtc atctctaata
    19801 acctttctgt aagcatactt catactattc taactaattt taccaaaaaa taccagaata
    19861 aataaacatt cgaaaaactt catgtggtca tgaacatttt aactattaaa ggataaaaca
    19921 aataacttta tcagtctaat tttgcagtaa aatgtgatag aatgggtaag actataaaaa
    19981 taactaaaag aaggacaaat atgacaattg gaattgataa gattggtttt gcaaccagtc
    20041 aatatgtctt gaaattggaa gatttagcgc ttgcacgcca agtggatcca gcaaaattta
    20101 gtcaagggct actcattgag tcttttagtg tggcaccaat cactgaagac attattactt
    20161 tagctgcttc tgcagcagat caaattttaa ccgacgaaga tcgatctaag attgatatgg
    20221 ttattttggc aactgaatcg agtactgatc agtcaaaggc atcagctatc tatgtacatc
    20281 acttagttgg tatccagcct tttgcacgtt cctttgaagt aaaacaagcc tgctatagcg
    20341 caactgctgc tctagactat gctaaactgc atgtggcttc taagccagat tctcgtgtcc
    20401 ttgttattgc tagtgatatt gctagatacg gtgtaggatc tcctggcgaa tcaactcaag
    20461 gctctggtag tattgctctt ttggtaactg ctaaccctcg tattcttgct ctaaataaag
    20521 ataatgtggc tcaaactagg gatattatgg acttttggag gcctaactat agtttcacac
    20581 cttatgttga tggtatttac tctaccaagc aatatctcaa ttgcttagaa accacgtggc
    20641 aagcttatca gaaaagagaa aaccttcagt tatctgattt tgctgcagtt tgtttccata
    20701 ttccatttcc caagttagcc ctaaaaggtc taaataacat tatggataac acagtacctc
    20761 ctgaacacag ggaaaaacta atagaagcct ttcaagcttc tattacttat agcaaacaaa
    20821 ttggaaatat ttatactggc tcactttatc taggattgtt atctttactt gaaaatagta
    20881 aagtattaca atctggagat aaaattggtt tttttagcta tggttccggt gccgtaagtg
    20941 aattttattc cggtcagtta gttgctggat acgataaaat gttaatgact aatcgacaaa
    21001 ctttactgga tcaacgaaca cgtctttccg tttctaaata cgaagacctt ttctacgaac
    21061 aagtccaatt agatgataat ggtaatgcca attttgacat ttacttaact ggaaaatttg
    21121 ctctaacagc catcaaggag catcgaagga tctatcatac caatgacaaa aactaatctt
    21181 aactggagcg gtttttcaaa gaaaacattc gaagaacgcc tccgacttat cgaaaaattt
    21241 aaactactta atgctgaaaa cttaaatcaa ctcaaaacag acgttctttt gcctatccaa
    21301 acagctaatc aaatgactga aaatgtctta ggacgattgg ctttgccctt tagcatagct
    21361 cctgattttc ttgtcaacgg ttcaacttat cagatgcctt ttgtcacgga agaaccttct
    21421 gttgttgctg cagcatcttt cgcagcaaaa ctaatcaaac gctcaggtgg ttttaaagct
    21481 caaaccctaa accgacaaat gattggtcaa attgttcttt acgatatcga ccaaatagat
    21541 aacgctaaag ccgccatcct tcataaaaca aaaaagctaa ttgcattggc aaataaagct
    21601 tatccttcca ttgttaaaag aggtggaggc gctagaacca ttcatttgga agaaaaagga
    21661 gagtttttga ttttctatct gactgttgat acccaagaag ctatgggagc aaatatggtc
    21721 aatactatga tggaagctct tgttcctgat ttaacaagac tgtctaaggg gcattgtcta
    21781 atggcgattt tatctaatta cgcaacagag tcgcttgtta ctactagttg tgagattccc
    21841 gtgcgccttt tagatcacga taaaacaaaa tccctacagt tagctcaaaa aatagagcta
    21901 gccagccgac tagctcaagt agatccttac cgggctacta ctcataataa aggtattttt
    21961 aatggcattg atgcagtggt aatagccaca ggaaatgact ggcgtgctat tgaagcaggg
    22021 gcccatgctt atgcctcaag aaatggtagc tatcaaggac ttagtcagtg gcattttgac
    22081 caagataaac aagttctgct tggccaaatg accctcccta tgcctattgc tagtaagggg
    22141 ggatctatcg ggcttaaccc tactgtttct atcgcacatg atcttcttaa tcaacctgat
    22201 gccaaaacat tagcccaatt gattgcatct gtggggttag ctcaaaactt tgctgcacta
    22261 aaagctctga cctcatctgg catccaagct ggtcacatga aactacatgc gaaatcatta
    22321 gctcttttgg cgggggcaac ccaagacgaa attgctcctt tagttaatgc tttactagct
    22381 gataaaccaa taaatctaga aaaagcacat ttttacttat cccagctaag acagtcttag
    22441 atttaaacaa ctaatataag gcaaacaccc atgtaaacaa ttggtttaca tgggtgttta
    22501 atctttgttt ctatacatac aagtcttaga aatagtctcc ataacatact ctatttactc
    22561 atctactcta ttctgagttt gatgaggtat ttataaatat tttatattat gttctaaaaa
    22621 agctctatca tctttgtagt aggtggcact attgtagagg tgatgaagcc taattgacct
    22681 gctgcaagcg tccatatagt aagtagtcga ctccctttaa ttctttaata gttttacagt
    22741 caagagcaca cataatgatt tttaattctt ctttccagcc gttaacgata gcaatcacac
    22801 gctcggttgg gtatttttcg accaattcta aaacggtgcg tgagagtccc actgcacgtg
    22861 ctcctaggac gaaacattta atcatatcca aggggtgtct gacaccaccc gaagctaaga
    22921 tttccacttg gtccatcagt ccttgtgcat ttagcaagca ctgaacggtg gtttgtcccc
    22981 aatcgtttaa gtaagagcgg tctcctcctc tttgattttc aatataggca aatgaggtcc
    23041 ctcctcttcc tgaaatatca aaggtttgaa tgcctaggtc atgtgctagc ttgatactat
    23101 tgacatccat gccaaaacca acttctttga gaatgacagg aactggtatt tgactagcgt
    23161 attcagcgag gtgttttttc caggtatgaa agacgcgctc accctctggc atcagcaact
    23221 cttgcatcac attcacatga acctgtaaaa agaggggctg catttcttga accgtttgtt
    23281 gtcctagcgc cacaggttta tctagaccaa tattcgtggc tagtttcaag ttatctgcca
    23341 cctcatgtaa acgataggaa tcgtcgttag gattttttaa agcagcgcta taagaccctg
    23401 tcaccatgac aatccctgtt gctgctgcta ctttggccaa tttttcattg acagctttgc
    23461 ctttttgact tcctcctgtc atggcattga tgtaaaaggg aaagtcgaag tcttgcccgg
    23521 caaaatgagt actgagatca atatcagaca aatcatagct aggtaaggaa tgatgtatga
    23581 gttctatgtc atcaaaagta ttataaggcg attggtactt gagggcatat ttgatgtgat
    23641 catctttacg gttggtcatt ctctccccac ctttcttgat aaagtaatgc gatatcagct
    23701 tcttgccatt tggaaataag ggtatctctg gcattctgat taaaggcaag cgcgatgcca
    23761 caatctccac caccagaacc tgaagattta gcaacagcat cttgcttctg acaagcagct
    23821 accaaggtta ctagcttagg atggtagata gctggatgaa gctcttttag gagatgactt
    23881 gctcctgcta aacttttctt gagttcttcc ttatgacctt cttgcaaagc taccatagct
    23941 gattgcgtta gctggtaact tgttcttaag aaagctgggg taatgctcgc tgtcacttgt
    24001 tgaatcatct gccttgaaat agcaggtatt ttagtccagc caaccaaaaa gtcacaaggc
    24061 agggctggtt gaatgacttg gatatggtaa ccccaatctt tgacgagaag tttttttaag
    24121 ggcatggtct gcagccagtt actgacctgt tctcggtcaa aggaggtata ggcgactaaa
    24181 gtctggtaag cgatacaggc aatatccccc atagacccat tatctccttg cttaagcaag
    24241 gtataagccg ctagtttaaa gagtaactct ggggttaaag tgatctgata ataggccgat
    24301 aaggccttta aggttaagag ggtgacgcta ccacttgaac caatgccaaa ttttttgcca
    24361 tcgcgctcca tttttcccgt tatgattagg gaaaatggct ccagttggtc aattgactgt
    24421 cctagataat cagcaaaggt tttaaccgtt gcttgaatca gtgcataaga ggcatcgggt
    24481 gtcatgcccg ctttatgggc aaacatatct gaagctaatt gaatatgggc tgctgggcta
    24541 atttctgctg tcatcatcag tggaataaag tgaattaagg ctttttgtcc tggtgttaag
    24601 atagcatatt cgcctgtgag gtatagtttc ccacctgttt gcacacaata attagacatc
    24661 tggtaaatcc tttgtttttg aaacgataat acggtagttc ttgccaagtc gttctgctag
    24721 ttgagccaag tctttttcta aacataggac cttcacattt ggacctgcgt ccatggtaaa
    24781 ataacaagca aaaccttctt gacgcagttc tttcacagcc tccatagcct ggtaagactc
    24841 ttttgttagg taagaaaaag gaggattggc tgtctttgtc gtggcatgca tggccaaggc
    24901 attagcttct gttaactgac caactttctc aaaattatta gttttgagat aggtaagcat
    24961 atgttggtaa tcgattgccg attgttctac ccattcatca aatgtagttg aggtatcgcg
    25021 gcataacttc atgccctctc ggctagaaat tggctttttc gcagcattta agaccagcat
    25081 aatcatggcc attttcaagt cagtctcaac cttgtaaata gcaccactat ctttgtccca
    25141 agcagcaact gggccaaaaa aagaacgaga agatgatcct gaggcgaact tagccttttg
    25201 agctaaagct ttctgatcta gctgagtgtc aaataattga tcacaggctt taaccaaggc
    25261 tgataagcca ctggaacttg atgataaacc tgcagctgtt ggcatattat tttgagtttc
    25321 catctttaca aaagcctgac caggttggcg aaattggtca atgatagtag aaattttggt
    25381 atgttcttcg tcattttgca agacaccgtt aatgtaaaac tgatcactgg ttgcagtatc
    25441 tggtaagaag gaaacgctgg ttgtggtgaa catgttttcc aaagtcaaag aaatgctaga
    25501 ggtcgaagga atcatcttag cttgattctc ttttccccaa tatttgataa tagcaatgtt
    25561 agcataggat gttacggtta taacatttgg atccacgtgt ttacggctcc ttcttctttt
    25621 aatctgtgac tgattttttc ggccatgtct ttggtatctg ctagggcaat catacagcca
    25681 cccaagccac cgcctgtcat cttagcgcct aaagcacctg ctcttagggc agcctccaca
    25741 agttggtcag ctttactgat gctaacgcca atggccttta aagcagagtg cgcttgtgtc
    25801 atgagctgac cgatagccac cttatttttt tggttaatcg ctctttcaag ggcttgtgtc
    25861 aaagctccta gtttagccag atagggcaaa ttcgtttcct caaactgtgc taccttattg
    25921 acggcctcac gtgtatgacc gtgaatccct gtatctgcaa tgataagata accatttaag
    25981 gcgatttcga tagtttcaaa gccaatgttt cggataaact taatggcatg gtcactaagg
    26041 catgtcttgg catctaaacc actaggattg gtgtgggcaa taatttctgc cttgttgact
    26101 aaaatttcca acaaatcatc cgagaggggt tcttgacaat aagaaaaaac ggctctaata
    26161 gctgcaatag aaacggctgc cgaagacccc ataccacgct tttgtggcac ttgtgaaaca
    26221 atctcataag caattggttc ttgtagtcgc tgcaaataat ccaaggcagc ataaatggct
    26281 gttgatagag tatcataaaa atcaaagacc aatggcttat cagctggaaa aatatgacaa
    26341 accacctcaa tatctgttaa aggcaaagca atagctgggt agccatacac aacagcatgc
    26401 tcacctatca aaatgatctt actgtgtgcc ttaccatatc caatgttttc gttcattttt
    26461 tatcttttca ttactaattc ttctaaactt ttaccttact attttacact aaatgattag
    26521 aaaatgcgat gatatatctt tttaaaatca tttcttcact gaaattaaca ataaagacta
    26581 tctactcttt ttaggatcat aacaaaaatt ttcttatttc aaactacctt ctttaatcac
    26641 tcttctacta aattaaacgt taaaaaccag cctcatgggc tggttaagca tcgtttatta
    26701 cctttaccta gacattatta ctagctaaag gtactgaaaa atgtttaagt caaatcacca
    26761 ctgtaaaaac aatagcatcg tttttataat ttacagttat cgttccttta aataacttaa
    26821 ccatactttc tgccatagat aaaccaattc cataaccttt ttctttgcta ttatgggatt
    26881 cgtcttcgcg ataaaagcgt tcaaaaaagc ggctgtaatc aatggatttt ccttccaaat
    26941 aggtattaga aacttctaat ttcgctcgtt ttcgtcttct tccaatagtg gttaaagata
    27001 ccttgaccaa gcctttagga tcacaatatt tattggcatt atcaactaaa attgtcacaa
    27061 gttcaaataa tgacttttcc tccgctttaa tcataatatt cggctgaatc gtcaaatcaa
    27121 aacgtttacc atctttcaaa accagactct taaaatcttc agctgcatct tgagcaatag
    27181 ctgaaaagtc taccatatgt aataccacat ctggctgttc ctccaaacga gccaaagtaa
    27241 tcatttgatt aatcaagcct gtcaatcgct tcacctgatc acttgtactc ttggtccatt
    27301 ctgattctcc agtcattaat tcgaccaatt cattattggc tgaaataatg gctagtggtg
    27361 tttttaactc gtggcctgca ttagtaataa agcggcgctg cttctcataa ttttggacaa
    27421 aaggtttgat gaccataccg gaaaaaagac tcactaaaac aacaaaaaag ataaatcctc
    27481 caaaggccaa catcattgaa acagctaata aatctcctac actacgaaaa taaaaggtag
    27541 tatctaaaat tacaaccagt ttttcttcat ttggcagctg agtaatcaag tacgaataaa
    27601 cactatcttg gtgacggtaa ctgccttttt cttccccaga cttagcaaaa agtctagcaa
    27661 aatattgggc ttcttctcca tctaaagctg aaatattagc agtattagaa gaaagtagat
    27721 gtccattagc attaaaaatg acactatagt accgaaactg gcttaggcta tcttcagaca
    27781 gtttcgttcc aagtcgttta gagctttccg tagtgtcagg taatttacct ttatttgagg
    27841 aaattaaatg taaaatacgg ttaatttctt gttgactttg gtaacagcgt gccgtgttaa
    27901 taataccaac aattgaactt aaaataataa aaatggcaat agaagcaatc atgataaaac
    27961 gaatacggat acgattaaac atgtcacctc ctatttttct aataaacaat agctagtatc
    28021 tttatcacct gcaataatga catttgcttg aatagctaat aatttttgac gaagataaga
    28081 aatataaacc caaacaatag aagtatcata atcttcttgg tctgaccaaa catgttggta
    28141 aagtgtttta gtatccaagt actttccttg atttaacatt aaaaaggcca ttaatttacc
    28201 ttctttagaa gctaatcgta tagcattacc ggcactcaat tcttgctcat taatatttaa
    28261 tgtgacacca gcaaattgta atacctgagg agtaaaactt tctactcgtc tttccatcga
    28321 tcttaatcta gctaaaagtt cttttaatga gaaaggttta gtcagataat catcagctcc
    28381 cgcatctagt ccggtaacac ggtcattaat ttctgccata gccgtcagca taataatatg
    28441 tgagcaattt cctgaagcgc gaatctcctt taaagcctca atgccagact taatcggcat
    28501 catgatatct aaaatcataa tatcatatgc attgtctttg gctttatcaa ttgcctcttg
    28561 accgttaaaa accacatcaa cgtcataacc ttgatgagtc atggcagttg tcaaaacatt
    28621 agacatctgc cattcgtctt cagctaacaa aattttcatg gttactcttc ctccgtcgtt
    28681 tcttgaatca attgacgaat ggtttgcatg gtaacatcac aagatgccaa ctcgtctgca
    28741 caacgcttta actctcttgt aatcatttct gcattagcaa cttgatgttt gtacttcatt
    28801 tgatgttcca agctagccca agagtcttga gcaatggttc gcaactgcac ttctataaaa
    28861 taacatcctt ttttttcccc taaaatatct ggaaaatgtg tttctaattc caaaatgaga
    28921 tgatatgatc tatagccatt aggcttggca tttaaaatat aatctttttc agtgttaact
    28981 gacataccag gaatgctttt gagcaagtct accatccgat aaatatcatc aataaaacca
    29041 caaataatgc gaataccgat actatcttta atgattttta acgcagattt gcttgttaga
    29101 ggaagctgtt tgcgttgaca tttttcaatc atcgaagctt ccgatttaat acgggatgta
    29161 aagtgttcgt atagtttaaa ccctgtttct tttttgcttt tgatattctc agcaataatc
    29221 acatctgtta ttgtctgtag taccaacggc aagtacactt caaatccgct atatatagag
    29281 ctggtagaat aatgttctag tctttctttc atacgcttat tataacaaat tttctcaaca
    29341 aatgcttaaa tctctgcaat gatcggttat ctttatttct aactatataa ctataaatga
    29401 tctgtatcgt ttgtttttaa atcgctttca tatatttttt gtacgttatt ttttaaaaat
    29461 accattgaat tacaaacaaa aacatagtaa acttgatcta taacgattac attaacttat
    29521 taggagattt tatgaaaaaa tattttattt taaaaagtag tgtattgagt atcctgacta
    29581 gttttactct attagttaca gacgttcaag cagatcaagt tgatgtgcaa ttccttggcg
    29641 tcaatgattt tcacggcgct cttgataata ccggaacagc ttacacacca agtggtaaaa
    29701 taccaaatgc tgggacggct gctcaattag gtgcttatat ggatgacgct gagatagact
    29761 tcaagcaagc aaatcaagac ggaacaagta tacgtgttca agctggagat atggtcggag
    29821 ccagtcctgc taactctgca cttttacaag atgagcctac tgtaaaagtc tttaacaaaa
    29881 tgaaatttga atatggcact cttggtaatc atgaatttga cgaaggacta gatgaattta
    29941 accgtatcat gacaggtcaa gcgcctgatc ctgaatcaac aattaatgat atcaccaaac
    30001 aatatgagca cgaagcttcg catcaaacca tcgtcattgc taatgttatt gataaaaaaa
    30061 ccaatgatat cccctatggt tggaaacctt atgctataaa agacatagcc attaatgaca
    30121 aaatcgttaa gattggcttc attggtgttg tgactacaga gattccaaat ctcgttttaa
    30181 agcaaaacta tgaacactat caatttttag atgtagctga aaccattgcc aaatatgcta
    30241 aagaactaca agaacaacat gttcatgcta ttgtggtttt agctcatgtt cctgcaacaa
    30301 gtaaagatgg tgttgttgat catgaaatgg ctacggttat ggaaaaagtg aaccaaatct
    30361 atcccgaaca tagcattgat attatttttg caggacataa tcatcaatac actaatggaa
    30421 ctatcggtaa aacacgtatc gttcaagccc tctctcaagg aaaagcttat gcagatgtcc
    30481 gtggtacgct agatactgat accaatgatt ttattaaaac tccatcagca aatgttgttg
    30541 ctgtagcacc aggtatcaaa acagaaaatt cagatatcaa agctataata aatcatgcta
    30601 atgatattgt taaaacagtt actgaacgaa aaatcggaac tgcaactaat tcttcaacta
    30661 tttctaaaac agaaaatatt gataaagaat ctcctgtcgg taacttagta acaacggctc
    30721 agcttactat tgctaagaaa acttttccaa ctgttgactt tgctatgacc aataatggtg
    30781 gtattcgaag tgacctagtt gtcaaaaatg accggaccat cacctgggga gctgcacagg
    30841 ctgtacaacc atttggtaat atccttcaag tcattcaaat gactggtcaa cacatttacg
    30901 atgtcctaaa tcagcaatac gatgaaaacc agacctattt tcttcaaatg tcaggtttaa
    30961 catacactta tacagataat gatcctaaga actctgatac ccccttcaag atagttaagg
    31021 tttataaaga caatggtgaa gaaattaact taacaactac ttacaccgtt gttgtcaacg
    31081 actttcttta tggtggtggt gatggctttt cagcatttaa aaaagctaaa ttaatcggag
    31141 ctattaacac agatactgaa gctttcatca catatatcac aaatttagaa gcatcaggta
    31201 aaactgttaa tgctactata aaagggatta aaaattatgt aacttcaaac cttgaaagtt
    31261 cgacaaaagt taatagtgct ggtaaacaca gtatcattag taaggttttt agaaatcgtg
    31321 atggcaatat agtgtctagt gaagtcattt cagacctttt gacttctact gaaaacacta
    31381 ataacagcct tggcaaaaaa gaaacaacga caaacaaaaa tactatctct agttccactc
    31441 ttccaataac aggggacaat tataaaatgt ctcctattat gacaatcctt gccttgataa
    31501 gcttaggtgg actaaacgct tttattaaaa aaaggaaatc ctagcgttta ctagtaatcg
    31561 atcaccctta tataatcagg catctttgcc aaaaaaacct aaagcgtcct actctaggtt
    31621 ttttgttaaa ttaaaatacc ttctagatga tctaattcgt gctggcatat ttgagcagtt
    31681 aagcctgtta agcttaatcg ctttggtcgc caattatggt ccaaatactc aacagtaatc
    31741 ttatcatacc gctgtgtttt gcgatagcca gataacgaca aacaagattc tttagtttgg
    31801 taaattccct ttttagaaac catcacagga ttaaacataa ccaaatcaat aaatcccata
    31861 ctcacaataa caatgcgctt ttgttcacca atcatattgg cagccatccc aagacattcc
    31921 tgtctataaa aggctaaggt atcttgtaaa tcttggccaa tccatagatc ttctttcttg
    31981 gcgacttgcg ctttttgttg taataaaaaa tgatctgtta tgatttctct aatcattctt
    32041 atctccttaa accttctttt taattcataa actacatgtt caatggacta ttatcaccat
    32101 atgatagact tagtatcatc tgtttaaaac atcaggtgat tccttatttc aagatatctt
    32161 gggcaacttt atgaaattct gcaatatgag taccaaataa aaattgacct gcatcagcag
    32221 attgttgcta agttctcatc acaatattat cgaatttact gtctgcttct tcaaatgtct
    32281 aagagagata gttattgctt tgtgagattt tcaaaccaga tactgctttc tcttgcattt
    32341 gcagccttaa caggtccaaa taaaacacct gctgtttgaa atgctttaat agctgatatg
    32401 ttgttaatag ttagtattat aaattttctg aatatttctg tcaagttttt cagttgactt
    32461 aactttttta cttgattttt cctcacgtaa taatagaaaa gaagcgccat aatgtaaact
    32521 gcaccccaaa cgttagatac aaaaccttaa cgtttggggt gtttttgtat gacattaagc
    32581 tatgaagata agctaaacat ttagcgctaa aaaaaccgag agaactccgt ttgaaagaag
    32641 catctctgaa aagaagaaga caaaaaacca ttataaagaa tggataaaga cgagttctga
    32701 ttagattttc ttttaaggac ggctaaattg actcgttcta cctactatta tcatcgatta
    32761 ttgcaacaat aaccgtatca aaataaaacg aaaaggactt agtcctctac aacacagaac
    32821 taaatccttt acttcaaata gagtagccaa cttttggggc tcagtgcaag agcccttctt
    32881 ttctattatc acttgtttat tataaacata acattaccat agtatactta tatgtctagt
    32941 ccactcaaat actcaaaccg ttcatacgcc aataataaat cattattgcg ctgatcgagt
    33001 tccttttgta attgagctaa ctggccataa tcactaacta cagttaacat ttggttttca
    33061 atttcttcaa tattagcctc aatagttgct attttatctt ctatctgagc ccattcttgt
    33121 ttttcaaggt aggacatgcg ctttttctcc tctttcggag gaagtggcac ttcttcagtg
    33181 actattgctt tagctaagtc agcctcaact gtttcttttt caaaagcttt ttcatcaagg
    33241 taatcactgt aattcccata aaaaatacga atatcgcctt cttcaaaagc taaaatctta
    33301 gtggctactt tgtctaggaa ataacgatcg tgactaaccg taatgactgg tcctgcaaag
    33361 ttagctaaaa agttttctaa gaccgtcaag gtggcaatgt ctaaatcatt tgttggctca
    33421 tcaaggagaa gaacatttgg cttttcaatg agcagtttta gcaagtagag ccgttttttc
    33481 tccccaccag ataatttagc aatcagcgtg ccatgacttg atctcggaaa aagaaattgc
    33541 tctaaaagct cactgatact cgttgttccc acgcttgttt taacctcatc agccacttct
    33601 tgaaggtaat taatgacccg tttggtctca tccatatctt tgagctgctg agagaaataa
    33661 cctacacgaa tagtatctcc aatatcaagc ttcccagaag ttggtttgag atcaccgtta
    33721 atgatattta acagggtaga ttttccgacg ccgttatctc caacaattcc aatacgatct
    33781 ttattttgaa taatcaagtt aaaatcctta atcaactgtc ggtcgccata agcaaaagaa
    33841 aggtcttcaa agtgaatcac cttcttccca attcggctcg tttcgaaagc catctccaat
    33901 ttatctgcag aactgtcttg gtgaacttct tttttcaagt cagtgaaacg attgattcta
    33961 gcctgctgtt tggttgcacg cgcctgtggc tgcgtcctca tccaagctaa ttcttgttta
    34021 tagagttgct tcttcttgtg taaattagca gcatctcgtt cgtcttgttc tgcttttaag
    34081 cgcacatagt cttggtaatt gccttgatat tctgtcagtc ccgctttatc caattcaaaa
    34141 atacgggtag ccacatgatc aaggaaataa cggtcatggg taataaaaag gacggttttt
    34201 ttagctgtct tgagataggt tgttaaccaa gcgatggtgt caatatcgag atggttggtc
    34261 ggctcatcca ataagagtaa gtcagcagct cctagcaata cttgagctaa ctggacacgt
    34321 cttctcatac cacctgatag gtctcccact ttttgttcca aatccgtgat gcctaatttt
    34381 gataggactg ttttgacatc actttcaata gaccaagcat ctaagcgatc catttcagac
    34441 atgagggact ctaagctttc ttgtttatct tcagtataat tcgccatcaa tagttcatat
    34501 tgacgaatca gttgaatcgc cttaacatca gatgacaata ccgtatctaa aacagaagct
    34561 gcatcgttaa attcaggatc ttgtgttaag taagcgattt tgtaatcatt ggctttagaa
    34621 aatggtgaat ggtctccgtc aaaaccaagc cttcccgaca agacatctaa aagagttgtt
    34681 tttcctgttc cattaacccc aataatccca atacggtcaa agtcatgaat aataaaggaa
    34741 atatcttgaa agacggtctt atctcccacc gtttttgtca atttctccac caaaaaatgg
    34801 ctcatgttgc taattcctct ctaacaaatg cttcaattgt agtgaaatca ttatctaggc
    34861 gcccctctac aatcgctaat tcaactttct caagcataag ccctagctga ggacctggtt
    34921 tcatcccaaa atccttaatc aggtgagaac cattaaggac gatatcgtgt ttgtcatgaa
    34981 taaccagtgc ctgatctaaa gtattaatat gatccatgtc aacggataag ctttgagctt
    35041 ttcggaggtc ttccactaga ctcgccattt tcttgccgta ctggtaaata tccaattttt
    35101 caaaagatct ttcctgacga attctataaa gagcaatcaa ctttgtgaca taacgctgaa
    35161 aatcatttga agtcttccat gcttttagga agcttttagg atcctcaatg gctaaactaa
    35221 tcatcacata agcccaagct tggtgatgat cactaaaggt aaagttatct ttcaaagaaa
    35281 ctatcagatg attcaagcct gcttcctgct gcttcaagcc tggtaaatag tcgtaagcct
    35341 gacaagcaat catggcagaa atcccttttc gccagtgcgg tgccatcaat aatttatcaa
    35401 attcagtaaa agaacgttcc acagaaattt tttccaatag aggtgaatgg ctcctcatag
    35461 cttcaaaagt tgtagcttca atgtcaaaat ccagactcgc cgcaaatcga aagcctctca
    35521 taatgcgtag tgcatcttct tcaaaacgtt cctctgcttt acccactgct cgtaaccgtt
    35581 tttgctttaa atcaatgagt cctctaaatt tatcaataac ttgaccattt tcatccaagg
    35641 ccaaggcatt gacggtgaag tctcttcgtt ttaagtcttc ctctaaagag cgcacaaaag
    35701 aaacctgact aggacggcga taatcaacat agatatcttc tgtcctaaag gttgtaattt
    35761 catactcacc gccattttca agcacgagca ctgtaccatg ttcaatgcca acatcgacag
    35821 ttctgttaaa aatcgcttta gtctcttcag gataggaact agttgcaata tctacatcat
    35881 gaatgggacg ctcgagtaaa acatctctga cgcttcctcc cacaaaatag gcttcataac
    35941 cagcttcttt tattttagtc aatatgggta aagccttctg aaactcagaa ggcattgtca
    36001 ttaatttcat acgttgtttt ctaacctatc atccaagtag cccaatctaa agtgtgatta
    36061 ggctacttgg attctatcac atcttgttat tgttttagtg attcttgcaa ttaactattt
    36121 tttctaatcg acaattaaag cctcggtgtt acgccaaatg caatggctcc ttctcctaaa
    36181 tgagtagcaa tcaccgctcc aaaatgaacc tcttcaatgt catattgata accactgtct
    36241 tgtaagagtc gtttcaagta atcagctttg tcttgtgctt ttgagtgaat aatagacaca
    36301 ttatactgac cgtctgctat caagtcattt aaaatctcaa ccaagcgttt catggctttc
    36361 ttttctgttc tcactttttc ataaacaaca atttttccct cttcatcaaa gcgtaaaata
    36421 ggtttaatac tcaaaagatt tccaagaaga gcagacccat ttgacaggcg tccgccttta
    36481 accagatgat taaggtcatc aaccataata aaggctgtcg tcccatcaat ctgttcttgc
    36541 agcttgttta aaatagcttg aaatgtcatt ccttgacgtg accaatctag cacatttttt
    36601 accatactac ctaaaggagc agatgtgatc ttactgtctg gaaatgccat ttcaatctca
    36661 ggatgttctt cagctaaaaa ttgaatattt tgccaaaagc ctgagattcc tccagctaag
    36721 aacaagccaa taacatgtgt ataaccctta gaagacaaaa gtcctaaaag attatctagt
    36781 tcagataaac ttggctgact tgtcttggga agattttggg agtcagccat cttttgataa
    36841 aaatcatcta tactcaaatt tcgaccttca aaataggtct catcgtcaat gataactggt
    36901 atatcaaggc taaaaatagc tttatcttgt ttcagatctg ttggtagtgt tgctgtactg
    36961 tcagtaatta ctgctaattt cattaatttt taaactccaa atgaatacct ggacgatcca
    37021 aggcaatttc tgtgacttca taagtcaatc gcttaaccat gtctagcaaa ggagcagcta
    37081 aggattcaac ttcctcttgc gtaaattcgc ttggtttatc cactaaacga tctaaaatac
    37141 gaaccatttg tgagatgacc ccactaataa caaattcctc tttgacaata acaaattgca
    37201 atacagatac aattactgtt tctttttgct gctcatcttt atcaatcaac tgaaaagtca
    37261 cttcaaaatt ggtttctggt gttccgtttt ctttttccca ctctaaattt ctagcatcat
    37321 aatggtactg gttgacaaat tctttttcac gaactaattg cattttttat tctccttggt
    37381 atcaatatga tccattatag catagatttg aaaattatta aagtagcccc taaactacta
    37441 ttttcgcata acgttttaaa cagtgctatc tctcgaacag atatctattt ttttcaccta
    37501 tttatattta gtcttcctta tactgacatt atatcaaaaa aacacccgtt agtggtcttg
    37561 tactgcacct caattaagac agaaccactg gtcaggtaag ttttaagtcc aggataaaaa
    37621 ggtttatcac caaggcctca tcatgcttag ccaagtattt cgaactagct tgtcttagct
    37681 ctagtcgctc aaacgtaaac cctaggcgtt caatccgccg caaaacctct ccaactaacc
    37741 catacttaaa cccatagggc ttaatcatcg ctccgccctt cttctccttt tatccattat
    37801 aaaataaaaa cgttttaaca gacaaaaaat aggaaagtac cagactattg gatttatttt
    37861 tttatctcaa actccattaa cgatgttgag ttaaaggcat tcaaaacaac atagatcgta
    37921 agctaacaag attttttatc aattgaacct atcgtcccca gttataccac gacctcttct
    37981 ggatgaggtc tttttttatt tgtctaattt catcaacgct tcttcccctc tttcttctat
    38041 cacagctctc ctattgctca cttcctcatg cagcaacata tcatcaaaaa accgttcatt
    38101 tttaagcaca accactactg tatctcttgt gatgtctcca ttgcaatcgc ttgtttaatt
    38161 ttattaaaaa ttatttaaaa aattaaatat tattttaaga acttgcaata atatatgtct
    38221 atattatata atttctttat cataaaatta tatagaaaaa ggtattctta tgagaaaaag
    38281 atgctattca acttcagctg cagtattggc agcagtgact ttatttgctc tatcggtaga
    38341 tcgtggtgtt atagcagata gtttttctgc taatcaagag attagatatt cggaagtaac
    38401 accttatcac gttacttccg tttggaccaa aggagttatt cctccagcaa acttcactca
    38461 aggcgaagat gtttttcacg ctccttatgt tgctaaccaa ggatggtatg atattaccaa
    38521 aacattcaat ggaaaagacg accttctttg cggggctgcc acagcaggga atatgcttca
    38581 ctggtggttc gatcaaaaca acgaaaaaat tgaagcatat ctaaaaaaac acccagataa
    38641 acaaaaaatc atgtttggtg atcaagaatt attggatgta agaaaagtta ttaatactaa
    38701 aggtgaccaa acaaatagcg agctttttaa ttatttccga gataaagctt tccccggttt
    38761 gtcagcacgc cgaattggag ttatgcctga tcttgtttta gatatgttta tcaatggtta
    38821 ttacttaaat gtttataaga cacagactac tgatgtcaat agaacctatc aagagaaaga
    38881 tcgccgaggt ggtatttttg acgccgtatt tacaagaggt gatcaaagta agctattgac
    38941 aagtcgtcat gattttaaag aaaaaaatct caaagaaatc agtgatctca ttaagaaaga
    39001 gttaatcgaa ggcaaggctc taggcctatc acacacctac gctaacgtac gcatcaacca
    39061 tgttataaac ctgtggggag ctgactttga ttctaacggg aaccttaaag ctatttatgt
    39121 aacagactct gatagtaatg catctattgg tatgaagaaa tactttgttg gtgttaattc
    39181 cgctggaaaa gtagctattt ctgctaaaga aataaaagaa gataatattg gtgctcaagt
    39241 actagggtta tttacacttt caacagggca agatagttgg aatcagacca attaaagcgt
    39301 atcaataaga aagaatacct tcaacagatg atggtattct aaggactaat actattgcag
    39361 ggaatttttt tatagatggg caacagcaaa aaacattaat aaatcctata aaaatcgata
    39421 aggatattgt tacgattcaa gagttcgatt ttaaaataag aaaatttttg atggaatcaa
    39481 aagaaattca tttgactaag tctccttatg taagggggag tttagaaatt cacagtaaaa
    39541 ataggaaaca tgaaaaaatc aatttatatg acgcaaaacc caatagcacc agatctgatg
    39601 tctttaaaaa atataaagac aataagacta taaacatgaa agatttcagc cattttgata
    39661 tttatctttg gactaaataa gctaaaagct ttggataaat atgatcaatt gacctataat
    39721 aacattgata ccaaatctaa aactgctcag attgaattgc gccccaaaag ttagacaaaa
    39781 aatctaataa ttggggtgtt tttgtctggc attaagttta gctaataacc ttgcttaaat
    39841 cacattaaac caataatgga aaaagacatc tccaaataaa tgctatgatg gaactatatg
    39901 atagagtgat caaggttggc aatatcaaca caactattat catcatttcc taaactctaa
    39961 aggaattcgt ccgtctatgt cacgtaaaag aaacagtcct gacaatagca tgatggaatc
    40021 tttctttggc atcttaaagt cagaaatgtt ctatggttat gagaataact ataaatcact
    40081 agaagactta gaataagcga ttacaaatga cattgattat tacaacgata aacatatcaa
    40141 agtaaaacta aaaggattta gttctgtaca atacagaact aaatccttta cttaaaatag
    40201 agtatccagc ttttttgggg tcagtgcaag cagattgttg ttagtgttac attaataagt
    40261 catgcgttta gcccaagcct catcaactgc tagggtctcc gcatcagtgt aattacgacg
    40321 atactcattc caaacataac ccgaagttgc tagaccagtt tcttgagctg agctattagc
    40381 aacatcataa gccgtcaaac cataggttgc aataatatta tttagtttta agttataact
    40441 ggtgtctgta gcgtataagc cagttagagc tgctgtagca tcttgatacg atagcgtgtt
    40501 tgattttcta gcacctatat aagtgctaga acttagcaag tctgcatagt cattaaggga
    40561 gtctgcaata cttggataag ctctaaaggc ttgatcaatc gtataggtat tgccattacc
    40621 atcatcttcc caagttgaca tcgtcacaga agaaccgtta taggcaccct taataccgaa
    40681 aaaattataa taaggtgctt gacttagact tgatttacca ttacttgatt ctaaaatcgc
    40741 ttgtgctatc ataacagacg cataaagatc acgttcttga ccaatagtac tagcagttgg
    40801 accaatttca tcaataaaat gtcgggttga agaactggcg atagtctcag ctgacacgtt
    40861 tgaagtttta tgagattgtc tcattgcact ataagctcct aaacaagctg ctagaacaaa
    40921 aagactgata agtacaagct tacctttctt ttttgtcatt attcacatat ccttttttat
    40981 acattttcta tgtttctatt atagcacacg aacgtttaaa ttaacttttc cacagataat
    41041 ttaatgagat tgataacttt tgtcttgaaa tcgacatatt tcttctgatt ttttttaaaa
    41101 ttgtggataa ctatttcatt agaccatcaa aattagtgag ttgataccat tcaatcaatt
    41161 catttaattt ggtatg
//
