LOCUS       NZ_CP035431            41176 bp    DNA     circular CON 15-OCT-2024
DEFINITION  Streptococcus pyogenes strain emm105 chromosome, complete genome.
ACCESSION   NZ_CP035431
VERSION     NZ_CP035431.1
KEYWORDS    RefSeq.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1800116)
  AUTHORS   Davies,M.R., McIntyre,L., Mutreja,A., Lacey,J.A., Lees,J.A.,
            Towers,R.J., Duchene,S., Smeesters,P.R., Frost,H.R., Price,D.J.,
            Holden,M.T.G., David,S., Giffard,P.M., Worthing,K.A., Seale,A.C.,
            Berkley,J.A., Harris,S.R., Rivera-Hernandez,T., Berking,O.,
            Cork,A.J., Torres,R.S.L.A., Lithgow,T., Strugnell,R.A., Bergmann,R.,
            Nitsche-Schmitz,P., Chhatwal,G.S., Bentley,S.D., Fraser,J.D.,
            Moreland,N.J., Carapetis,J.R., Steer,A.C., Parkhill,J., Saul,A.,
            Williamson,D.A., Currie,B.J., Tong,S.Y., Dougan,G. and Walker,M.J.
  TITLE     Atlas of group A streptococcal vaccine candidates compiled using
            large scale comparative genomics
  JOURNAL   Nat. Genet. (2019) In press
REFERENCE   2  (bases 1 to 1800116)
  AUTHORS   Davies,M.R., McIntyre,L., Mutreja,A., Lacey,J.A., Lees,J.A.,
            Towers,R.J., Duchene,S., Smeesters,P.R., Frost,H.R., Price,D.J.,
            Holden,M.T.G., David,S., Giffard,P.M., Worthing,K.A., Seale,A.C.,
            Berkley,J.A., Harris,S.R., Rivera-Hernandez,T., Berking,O.,
            Cork,A.J., Torres,R.S.L.A., Lithgow,T., Strugnell,R.A., Bergmann,R.,
            Nitsche-Schmitz,P., Chhatwal,G.S., Bentley,S.D., Fraser,J.D.,
            Moreland,N.J., Carapetis,J.R., Steer,A.C., Parkhill,J., Saul,A.,
            Williamson,D.A., Currie,B.J., Tong,S.Y., Dougan,G. and Walker,M.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2019) Department of Microbiology and Immunology,
            University of Melbourne, The Doherty Institute of Infection and
            Immunology, Melbourne, Victoria 3000, Australia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 80x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_005161125.1-RS_2024_10_13
            Annotation Date                   :: 10/13/2024 02:15:04
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,766
            CDSs (total)                      :: 1,677
            Genes (coding)                    :: 1,600
            CDSs (with protein)               :: 1,600
            Genes (RNA)                       :: 89
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 39 of 77
            Pseudo Genes (incomplete)         :: 46 of 77
            Pseudo Genes (internal stop)      :: 21 of 77
            Pseudo Genes (multiple problems)  :: 21 of 77
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:05:46
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 699899
            Orig. end                         :: 741075
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP035431.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..41176
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="T3PKS"
                     /region_number="3"
                     /rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /tool="antismash"
     cand_cluster    1..41176
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /kind="single"
                     /product="T3PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..41176
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:21176](-)"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(20001..21176)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
     gene            416..1123
                     /locus_tag="ETT68_RS03715"
                     /old_locus_tag="ETT68_03710"
     CDS             416..1123
                     /GO_function="GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990206.1"
                     /locus_tag="ETT68_RS03715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT68_03710"
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="WP_002985031.1"
                     /transl_table=11
                     /translation="MTKKKGKLVLISLFVLAACLGAYSAMRQSHKTSNVSAETIASSST
                     RHFIDEIGPTASTIGQERDLYASVMIAQAILESSNGKSSLSQAPYHNFFGIKGAYNGSS
                     VTMSTWEDDGNGNTYTIDQAFRAYPSIADSLNDYADLLSSSTYIGARKSNTLSYQDATA
                     ALTGLYATDTSYNLKLNNIIATYGLTAYDVANSSAQETGLATSGYVWNEYRRNYTDAET
                     LAVDEAWAKRMTY"
     gene            complement(1180..>1470)
                     /locus_tag="ETT68_RS03720"
                     /old_locus_tag="ETT68_03715"
                     /pseudo=""
     CDS             complement(1180..>1470)
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1026: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611514.1"
                     /locus_tag="ETT68_RS03720"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="ETT68_03715"
                     /product="IS3 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="SDQGWQYQHNYYHHFLNSKGIRPSMSRKRNSPDNGMMESFFGILK
                     SEMFYGYENNYKSLEDLEQAITNGIDYYNDKHIKVKLKGFSSVQYRTKSFT"
     gene            complement(1695..1847)
                     /locus_tag="ETT68_RS09425"
                     /old_locus_tag="ETT68_03720"
     CDS             complement(1695..1847)
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014875.5"
                     /locus_tag="ETT68_RS09425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT68_03720"
                     /product="exotoxin beta-grasp domain-containing protein"
                     /protein_id="WP_079992508.1"
                     /transl_table=11
                     /translation="MHSKNRKHEKINLYDAKPNSTRSDVFKKYKDNKTINMKDFSHFDI
                     YLWTK"
     gene            complement(1837..2019)
                     /locus_tag="ETT68_RS09430"
                     /old_locus_tag="ETT68_03725"
     CDS             complement(1837..2019)
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014875.5"
                     /locus_tag="ETT68_RS09430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT68_03725"
                     /product="exotoxin beta-grasp domain-containing protein"
                     /protein_id="WP_136275577.1"
                     /transl_table=11
                     /translation="MREFFYRWATAKTLINPIKIDKDIVTIQEFDFKIRKFLMESKEIY
                     LTKSPYIRGEFRNSQ"
     gene            complement(2000..2914)
                     /locus_tag="ETT68_RS03735"
                     /old_locus_tag="ETT68_03730"
                     /pseudo=""
     CDS             complement(2000..2914)
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635407.1"
                     /locus_tag="ETT68_RS03735"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases.; frameshifted; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="ETT68_03730"
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRKRWYSTSAAVLAAVTLFALSVDRGVIADSFSANQEIRYSEVT"
     misc_feature    complement(2937..2950)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.62"
                     /tool="antismash"
     misc_feature    2981..2994
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.36"
                     /tool="antismash"
     gene            3418..>3575
                     /locus_tag="ETT68_RS03740"
                     /old_locus_tag="ETT68_03735"
                     /pseudo=""
     CDS             3418..>3575
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051153.1"
                     /locus_tag="ETT68_RS03740"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="ETT68_03735"
                     /product="nucleoside-diphosphate kinase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MIKPDGFKYGLVGEVLRRIERLGFTFERLELRQASSKYLAKHDEA
                     LMINLFI"
     gene            3823..4203
                     /locus_tag="ETT68_RS03745"
                     /old_locus_tag="ETT68_03740"
     CDS             3823..4203
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985011.1"
                     /locus_tag="ETT68_RS03745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT68_03740"
                     /product="DUF1149 family protein"
                     /protein_id="WP_002985011.1"
                     /transl_table=11
                     /translation="MQLVREKEFVNQYHYDARNLEWEKENGTPETNFEVTFQLIDKDEQ
                     QKETVIVSVLQFVIVKEEFVISGVISQMVRILDRLVDKPSEFTQEEVESLAAPLLDMVK
                     RLTYEVTEIALDRPGIHLEFKN"
     gene            4203..5051
                     /locus_tag="ETT68_RS03750"
                     /old_locus_tag="ETT68_03745"
     CDS             4203..5051
                     /GO_function="GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985007.1"
                     /locus_tag="ETT68_RS03750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT68_03745"
                     /product="DegV family protein"
                     /protein_id="WP_109991867.1"
                     /transl_table=11
                     /translation="MKLAVITDSTATLPTDLKQDKAIFSLDIPVIIDDETYFEGRNLSI
                     DDFYQKMADSRNLPKTSQPSLSELDNLLGLLSSKGYTHVIGLFLAGGISGFWQNIQFLA
                     EEHPEIEMAFPDSKITSAPLGSMVKNVLDWSRQGMTFQAILNKLQEQIDGTTAFIMVDD
                     LNHLVKGGRLSNGSALLGNLLSIKPILRFDEEGKIVVYEKVRTEKKAMKRLVEILNDLI
                     ADGQYNVSIIHSKAQDKADYLKRLLQDSGYQYDIEEVHFGAVIATHLGEGAIAFGVTPR
                     L"
     gene            5176..6384
                     /locus_tag="ETT68_RS03755"
                     /old_locus_tag="ETT68_03750"
     CDS             5176..6384
                     /EC_number="2.7.7.72"
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880307.1"
                     /locus_tag="ETT68_RS03755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT68_03750"
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="WP_168410068.1"
                     /transl_table=11
                     /translation="MKLMTMPSEFQKALPILTKIKEAGYEAYFVGGSVRDVLLERPIHD
                     VDIATSSYPEETKAIFNRTVDVGIEHGTVLVLENGGEYEITTFRTEDVYVDYRRPSQVS
                     FVRSLEEDLKRRDFTVNALALDENGQVIDKFRGLIDLKQKRLRAVGKAEERFEEDALRI
                     MRGFRFAASLDFDIEAATFEAMRSHSPLLEKISVERSFTEFDKLLTAPHWRKGISAMIA
                     CQAYDYLPGLKQQEAGLNHLIVSLKDNFTFSDHHQAWAYVMISLAIEDPKSFLKAWKTS
                     NDFQRYVTKLIALYRIRQERSFEKLDIYQYGKKMASLVEGLRKAQSLSVDMDHINTLDQ
                     ALVIHDKHDIVLNGSHLIKDFGMKPGPQLGLMLEKVELAIVEGRLDNDFTTIEAFVREE
                     LAT"
     gene            6381..8258
                     /locus_tag="ETT68_RS03760"
                     /old_locus_tag="ETT68_03755"
     CDS             6381..8258
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922163.1"
                     /locus_tag="ETT68_RS03760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT68_03755"
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="WP_109991866.1"
                     /transl_table=11
                     /translation="MSHFLVEKLTKTVGDKTVFQDISFIIHDFDRIGIIGVNGTGKTTL
                     LDVLSGRLGFDGDHSPFSKANDYKIAYLTQDPEFNDAASVLDTVLSSDVKAIRLIRQYE
                     LLMANYTEDKQESLESLMSEMDRLDAWSIESDVKTVLSKLGITDLEQKVGDLSGGMRRR
                     VQLAQVLLGAADLLLLDEPTNHLDIDTIAWLTTYLKTAKKTVLFITHDRYFLDHVATRI
                     FELDKAGLTEYQGNYQDYVRLKAEQDERDAANLHKKKQLYKQELAWMRTQPQARATKQQ
                     ARINRFTDLKKEVHQDSSADKLEMAFETSRIGKKVIHFEDLSFAYGDRQLIKDFNLIIQ
                     NKDRIGIVGDNGVGKSTLLNIINGDLKPTSGKLDIGDTIRVGYFSQQLKDMDETKRVIN
                     YLQEVADEVKTSVGTTSISELLEQFLFPRSSHGTLIAKLSGGEKKRLYLLKLLIEKPNV
                     LLLDEPTNDLDIATLTVLENFLANFAGPVITVSHDRYFLDKVATKILAFEEGDIRIFYG
                     NYSDYLDEKAFEKETVEADLAKAIVTEEVPLPPKEEKKRMSYLEKQEWAQIEDKIATIE
                     ANIEEIENQMLTVVSDYGQLAQLQKELDQRNNDLLLAYERFEYLSGLDI"
     gene            complement(<8356..>8433)
                     /locus_tag="ETT68_RS09435"
                     /pseudo=""
     CDS             complement(<8356..8433)
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /locus_tag="ETT68_RS09435"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS3 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MDYCNNKRIKIKRKGLSPLQHRTKSF"
     gene            8676..8894
                     /locus_tag="ETT68_RS09230"
                     /old_locus_tag="ETT68_03760"
     CDS             8676..8894
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995561.1"
                     /locus_tag="ETT68_RS09230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT68_03760"
                     /product="hypothetical protein"
                     /protein_id="WP_011106820.1"
                     /transl_table=11
                     /translation="MALLFYYYVRKNQVKKLSQLKNLTEIFRKFIILTINNISAIKAFQ
                     TAGVLFGPVKAANARESSIWFENLTKQ"
     gene            9148..9558
                     /locus_tag="ETT68_RS03770"
                     /old_locus_tag="ETT68_03765"
     CDS             9148..9558
                     /EC_number="3.5.1.88"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017671.1"
                     /locus_tag="ETT68_RS03770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT68_03765"
                     /product="peptide deformylase"
                     /protein_id="WP_002990188.1"
                     /transl_table=11
                     /translation="MIREIITDHFLLQQKAQVAKKEDLWIGQDLQDTLAFYRQECLGMA
                     ANMIGEQKRIVIVSMGFIDLVMFNPVMVSKKGIYQTKESCLSLSGYRKTQRYDKITVEY
                     LDHNWRPKRLNLTGLTAQICQHELDHLEGILI"
     gene            complement(9640..11645)
                     /locus_tag="ETT68_RS03775"
                     /old_locus_tag="ETT68_03770"
                     /pseudo=""
     CDS             complement(9640..11645)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888982.1"
                     /locus_tag="ETT68_RS03775"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="ETT68_03770"
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MKKYFILKSSVLSILTSFTLLVTDVQADQVDVQFLGVNDFHGALD
                     NTGTAYTPSGKIPNAGTAAQLGAYMDDAEIDFKQANQDGTSIRVQAGDMVGASPANSAL
                     LQDEPTVKVFNKMKFEYGTLGNHEFDEGLDEFNRIMTGQAPDPESTINDITKQYEHEAS
                     HQTIVIIKKLMISPMVGNLML"
     misc_feature    11621..11634
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.33"
                     /tool="antismash"
     misc_feature    11636..11649
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.93"
                     /tool="antismash"
     misc_feature    complement(11637..11650)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.3"
                     /tool="antismash"
     misc_feature    complement(11716..11729)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.6"
                     /tool="antismash"
     gene            11865..12515
                     /locus_tag="ETT68_RS03780"
                     /old_locus_tag="ETT68_03775"
     CDS             11865..12515
                     /GO_process="GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984988.1"
                     /locus_tag="ETT68_RS03780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT68_03775"
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="WP_002984988.1"
                     /transl_table=11
                     /translation="MKERLEHYSTSSIYSGFEVYLPLVLQTITDVIIAENIKSKKETGF
                     KLYEHFTSRIKSEASMIEKCQRKQLPLTSKSALKIIKDSIGIRIICGFIDDIYRMVDLL
                     KSIPGMSVNTEKDYILNAKPNGYRSYHLILELETHFPDILGEKKGCYFIEVQLRTIAQD
                     SWASLEHQMKYKHQVANAEMITRELKRCADELASCDVTMQTIRQLIQETTEEE"
     gene            12518..13186
                     /locus_tag="ETT68_RS03785"
                     /old_locus_tag="ETT68_03780"
     CDS             12518..13186
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984985.1"
                     /locus_tag="ETT68_RS03785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT68_03780"
                     /product="response regulator transcription factor"
                     /protein_id="WP_002984985.1"
                     /transl_table=11
                     /translation="MKILLAEDEWQMSNVLTTAMTHQGYDVDVVFNGQEAIDKAKDNAY
                     DIMILDIMMPIKSGIEALKEIRASGNCSHIIMLTAMAEINDRVTGLDAGADDYLTKPFS
                     LKELLARLRSMERRVESFTPQVLQFAGVTLNINEQELSAGNAIRLASKEGKLMAFLMLN
                     QGKYLDTKTLYQHVWSDQEDYDTSIVWVYISYLRQKLLAIQANVIIAGDKDTSYCLLEK
                     "
     gene            13195..14427
                     /locus_tag="ETT68_RS03790"
                     /old_locus_tag="ETT68_03785"
     CDS             13195..14427
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888981.1"
                     /locus_tag="ETT68_RS03790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT68_03785"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_002990181.1"
                     /transl_table=11
                     /translation="MFNRIRIRFIMIASIAIFIILSSIVGIINTARCYQSQQEINRILH
                     LISSNKGKLPGTTESSKRLGTKLSEDSLSQFRYYSVIFNANGHLLSSNTANISALDREE
                     AQYFARLFAKSGEEKGSYRHQDSVYSYLITQLPNEEKLVVILDTTFYFRSVGDLLAVSM
                     MLAFGGFIFFVVLVSLFSGMVIKPFVQNYEKQRRFITNAGHELKTPLAIISANNELVEL
                     MTGESEWTKSTSDQVKRLTGLINQMITLARLEEQPDVVLHMVDFSAIAQDAAEDFKSLV
                     LKDGKRFDLTIQPNIMIKAEEKSLFELVTILVDNANKYCDPKGLVKVSLTTIGRRRKRA
                     KLEVSNTYLEGKSIDYSRFFERFYREDESHNSKEKGYGIGLSMAESMVKLFKGTITVNY
                     KNDAIVFTVVI"
     gene            14721..15599
                     /gene="mvk"
                     /locus_tag="ETT68_RS03795"
                     /old_locus_tag="ETT68_03790"
     CDS             14721..15599
                     /EC_number="2.7.1.36"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004496 - mevalonate kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016126 - sterol biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /gene="mvk"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054375.1"
                     /locus_tag="ETT68_RS03795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT68_03790"
                     /product="mevalonate kinase"
                     /protein_id="WP_002984974.1"
                     /transl_table=11
                     /translation="MNENIGYGKAHSKIILIGEHAVVYGYPAIALPLTDIEVVCHIFPA
                     DKPLVFDFYDTLSTAIYAALDYLQRLQEPIAYEIVSQVPQKRGMGSSAAVSIAAIRAVF
                     SYCQEPLSDDLLEILVNKAEIIAHTNPSGLDAKTCLSDHAIKFIRNIGFETIEIALNGY
                     LIIADTGIHGHTREAVNKVAQFEETNLPYLAKLGALTQALERAINQKNKVAIGQLMTQA
                     HSALKAIGVSISKADQLVEAALRAGALGAKMTGGGLGGCMIALADTKDMAEKISHRLKE
                     EGAVNTWIQML"
     gene            15581..16525
                     /gene="mvaD"
                     /locus_tag="ETT68_RS03800"
                     /old_locus_tag="ETT68_03795"
     CDS             15581..16525
                     /EC_number="4.1.1.33"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA]"
                     /GO_process="GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /gene="mvaD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888980.1"
                     /locus_tag="ETT68_RS03800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT68_03795"
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="WP_002984972.1"
                     /transl_table=11
                     /translation="MDPNVITVTSYANIAIIKYWGKENQAKMIPSTSSISLTLENMFTT
                     TSISFLPDTATSDQFYINGVLQNDEEHTKISAIIDQFRQPGQAFVKMETQNNMPTAAGL
                     SSSSSGLSALVKACDQLFNTQLDQKALAQKAKFASGSSSRSFFGPVAAWDKDSGAIYKV
                     ETDLKMAMIMLVLNAAKKPISSREGMKLCRDTSTTFDEWVEQSAIDYQHMLTYLKTNNF
                     EKVGQLTEANALAMHATTKTANPPFSYLTKESYQAMEAVKELRQEGFACYFTMDAGPNV
                     KVLCLEKDLAQLAERLGKNYRIIVSKTKDLPDV"
     gene            16518..17525
                     /locus_tag="ETT68_RS03805"
                     /old_locus_tag="ETT68_03800"
     CDS             16518..17525
                     /EC_number="2.7.4.2"
                     /GO_function="GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016126 - sterol biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054377.1"
                     /locus_tag="ETT68_RS03805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT68_03800"
                     /product="phosphomevalonate kinase"
                     /protein_id="WP_021299363.1"
                     /transl_table=11
                     /translation="MSNYCVQTGGKLYLTGEYAILTPGQKALIHFIPLMMTAEISPAAH
                     IQLASDMFAHKAGMTPDASYALIQATVKTFADYLGQSIDQLEPFSLIITGKMERDGKKF
                     GIGSSGSVTLLTLKALSAYYQITLTPELLFKLAAYTLLKQGDNGSMGDIACIAYQTLVA
                     YTSFDREQVSNWLQTMPLKKLLVKDWGYHIQVIQPALPCDFLVGWTKIPAISRQMIQQV
                     TASITPAFLRTSYQLTQSAMVALQEGHKEELKKSLAGASHLLKELHPAIYHPKLVTLVA
                     ACQKQDAVAKSSGSGGGDCGIALAFNQDARDTLISKWQEADIALLYQERWGEND"
     gene            17518..18507
                     /gene="fni"
                     /locus_tag="ETT68_RS03810"
                     /old_locus_tag="ETT68_03805"
     CDS             17518..18507
                     /EC_number="5.3.3.2"
                     /GO_function="GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="fni"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984966.1"
                     /locus_tag="ETT68_RS03810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT68_03805"
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="WP_109991865.1"
                     /transl_table=11
                     /translation="MTNRKDDHIKYALKYQSPYSAFDDIELIHHSLPSYDLSDIDLSTH
                     FAGQDFDFPFYINAMTGGSQKGKAVNEKLAKVAAATGIVMVTGSYSAALKNPNDDSYRL
                     HEVADNLKLATNIGLDKPVALGQQTVQEMQPLFLQVHVNVMQELLMPEGERVFHTWKKH
                     LAEYASQIPVPVILKEVGFGMDVNSIKLAHDLGIQTFDISGRGGTSFAYIENQRGGDRS
                     YLNDWGQTTVQCLLNAQGLMDQVEILASGGVRHPLDMIKCFVLGARAVGLSRTVLELVE
                     KYPTERVIAIVNGWKEELKIIMCALDCKTIKELKGVDYLLYGRLQQVN"
     gene            complement(18737..20014)
                     /locus_tag="ETT68_RS03815"
                     /old_locus_tag="ETT68_03810"
     CDS             complement(18737..20014)
                     /EC_number="1.1.1.88"
                     /GO_function="GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA]"
                     /GO_function="GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1187: hydroxymethylglutaryl-CoA reductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880299.1"
                     /locus_tag="ETT68_RS03815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT68_03810"
                     /product="hydroxymethylglutaryl-CoA reductase, degradative"
                     /protein_id="WP_002984963.1"
                     /transl_table=11
                     /translation="MTKTNLNWSGFSKKTFEERLQLIEKFKLLNAENLNQLKTDVLLPI
                     QTANQMTENVLGRLALPFSIAPDFLVNGSTYQMPFVTEEPSVVAAASFAAKLIKRSGGF
                     KAQTLNRQMIGQIVLYDIDQIDNAKAAILHKTKKLIALANKAYPSIVKRGGGARTIHLE
                     EKGEFLIFYLTVDTQEAMGANMVNTMMEALVPDLTRLSKGHCLMAILSNYATESLVTTS
                     CEIPVRLLDRDKTKSLQLAQKIELASRLAQVDPYRATTHNKGIFNGIDAVVIATGNDWR
                     AIEAGAHAYASRNGSYQGLSQWHFDQDKQVLLGQMTLPMPIASKGGSIGLNPTVSIAHD
                     LLNQPDAKTLAQLIASVGLAQNFAALKALTSSGIQAGHMKLHAKSLALLAGATQDEIAP
                     LVNALLADKPINLEKAHFYLSQLRQS"
     gene            complement(20001..21176)
                     /locus_tag="ETT68_RS03820"
                     /old_locus_tag="ETT68_03815"
     CDS             complement(20001..21176)
                     /EC_number="2.3.3.10"
                     /GO_function="GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043: hydroxymethylglutaryl-CoA synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993959.1"
                     /locus_tag="ETT68_RS03820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT68_03815"
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="WP_021299369.1"
                     /sec_met_domain="Chal_sti_synt_N (E-value: 8.4e-07,
                     bitscore: 25.3, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIGIDKIGFATSQYVLKLEDLALARQVDPAKFSQGLLIESFSVA
                     PITEDIITLAASAADQILTDEDRAKIDMVILATESSTDQSKASAIYVHHLVGIQPFARS
                     FEVKQACYSATAALDYAKLHVASKPDSRVLVIASDIARYGVGSPGESTQGSGSIALLVT
                     ANPRILALNKDNVAQTRDIMDFWRPNYSFTPYVDGIYSTKQYLNCLETTWQAYQKRENL
                     QLSDFAAVCFHIPFPKLALKGLNNIMDNTVPPEHREKLIEAFQASITYSKQIGNIYTGS
                     LYLGLLSLLENSKVLQSGDKIGFFSYGSGAVSEFYSGQLVAGYDKMLMTNRQALLDQRT
                     RLSVSKYEDLFYEQVQLDDNGNANFDIYLTGKFALTAIKEHQRIYHTNDKN"
     gene            21385..22224
                     /locus_tag="ETT68_RS03825"
                     /old_locus_tag="ETT68_03820"
     CDS             21385..22224
                     /EC_number="2.1.1.45"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /locus_tag="ETT68_RS03825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT68_03820"
                     /product="thymidylate synthase"
                     /protein_id="WP_011017679.1"
                     /transl_table=11
                     /translation="MTKADQIFKANIQKIINEGSLSEQARPKYKDGRTAHSKYITGAFA
                     EYDLAKGEFPITTLRPIPIKSAIKELFWIYQDQSNSLDVLEAKYNVHYWNEWEVDQTRT
                     IGQRYGAVVKKHDIISKILKQLAENPWNRRNVISLWDYEAFEETKGLLPCAFQIMFDVR
                     RVGEDLYLDASLTQRSNDILVAHHINAMQYVALQMMIAKHFGWKIGKFFYFVNNLHIYD
                     NQFDQAQELLKRQPVASQPKLVLNVPDGTNFFDIKPDDFELQNYDPVKPQLHFDLAI"
     misc_feature    21415..21429
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 23.77"
                     /tool="antismash"
     gene            22304..22801
                     /locus_tag="ETT68_RS03830"
                     /old_locus_tag="ETT68_03825"
     CDS             22304..22801
                     /EC_number="1.5.1.3"
                     /GO_function="GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005542 - folic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984955.1"
                     /locus_tag="ETT68_RS03830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT68_03825"
                     /product="dihydrofolate reductase"
                     /protein_id="WP_136275579.1"
                     /transl_table=11
                     /translation="MTKEIIAIWAEDEAGLIGVAGKLPWYLPKELEHFKKTTLHQAILM
                     GRVTFEGMNCKRLPQRQTLVMTRNRDYQVDEVLTMTSIEKVLEWYHAQDKTLYILGGNK
                     VLEAFNGYFDRIIKTVIHHRFKGDTYRPNLDFSHFTQESQTFYARDAKNPYDFTVTALK
                     HK"
     gene            22821..22991
                     /locus_tag="ETT68_RS03835"
                     /old_locus_tag="ETT68_03830"
     CDS             22821..22991
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302775.1"
                     /locus_tag="ETT68_RS03835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT68_03830"
                     /product="hypothetical protein"
                     /protein_id="WP_002990165.1"
                     /transl_table=11
                     /translation="MQRSIFGVFTAFLCVICVLCAIPAFKKNRYGLGSLFLLNAFTNLV
                     NSIHAFYGTLF"
     gene            23121..24350
                     /gene="clpX"
                     /locus_tag="ETT68_RS03840"
                     /old_locus_tag="ETT68_03835"
     CDS             23121..24350
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="clpX"
                     /gene_functions="other (smcogs) SMCOG1223: ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984948.1"
                     /locus_tag="ETT68_RS03840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT68_03835"
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="WP_002984948.1"
                     /transl_table=11
                     /translation="MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEI
                     IKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDRAKRALSVAVYNHYKRVSFTESRDD
                     DDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENILLK
                     LIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVP
                     PQGGRKHPNQEMIQIDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASY
                     MQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIQILTEPRNALVKQYQALLSYDG
                     VELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVE
                     GKSKPVLETA"
     gene            24360..24959
                     /gene="yihA"
                     /locus_tag="ETT68_RS03845"
                     /old_locus_tag="ETT68_03840"
     CDS             24360..24959
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0043022 - ribosome binding [Evidence IEA]"
                     /GO_process="GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="yihA"
                     /gene_functions="other (smcogs) SMCOG1227: ribosome
                     biogenesis GTP-binding protein YsxC"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054379.1"
                     /locus_tag="ETT68_RS03845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT68_03840"
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="WP_002984945.1"
                     /transl_table=11
                     /translation="MAEEQVLNTHNASILLSAANKSHYPQDDLPEIALAGRSNVGKSSF
                     INTILGRKNLARTSSKPGKTQLLNFFNIDDKLRFVDVPGYGYAKVSKSERAKWGKMIEE
                     YLTSRDNLRAVVSLVDLRHAPSKEDIQMYDFLKYYDIPVIVVATKADKIPRGKWNKHES
                     VVKKALNFDKSDTFIVFSSVERIGIDDSWDAILEQV"
     gene            25107..25856
                     /locus_tag="ETT68_RS03850"
                     /old_locus_tag="ETT68_03845"
     CDS             25107..25856
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054380.1"
                     /locus_tag="ETT68_RS03850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT68_03845"
                     /product="hypothetical protein"
                     /protein_id="WP_023612039.1"
                     /transl_table=11
                     /translation="MTQVAQGRSKGKSLLCHQCNALFVFIIFLILLAVLFGVRYRNSSI
                     EGIWRTTSIDQKLGDDFAKRLTGLHQSPLIDDSLLTSSQMILTVKNNNVDLSFSVQVER
                     DIFVKRLAAYHQNELLKTLKENHLVVGDLSSKERQIIENSMPASHELEMILDQAFEKLA
                     SQIGGKYNQKTGHLSAVVLKGKVNRILHTIDIKEEVAAGHTSFSKGLLTPNGYFDYTRF
                     GKKLELLGDEKIIFKKALKKKSVKCIT"
     gene            complement(25909..28008)
                     /locus_tag="ETT68_RS03855"
                     /old_locus_tag="ETT68_03850"
     CDS             complement(25909..28008)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1223: ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922175.1"
                     /locus_tag="ETT68_RS03855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT68_03850"
                     /product="AAA family ATPase"
                     /protein_id="WP_109991863.1"
                     /transl_table=11
                     /translation="MTHFSGKDPFVNMDDIFNQLMANMGGYRSENPRYLVNGREITPEE
                     FQHYRQTGQLPVATTKATNSQMLTPKADSVLTQLGTNLTQEARQGHLDPVIGRNKEIQD
                     TAEILARRTKNNPVLVGDAGVGKTAVIEGLAQAIVNGDVPAAIKNKEIVSIDISSLEAG
                     TQYRGSFEETIQNLIQEVKEAGNIILFFDEIHQIVGAGATSSDSGSKGLADILKPALSR
                     GELTLIGATTQDEYRNTILKNAALARRFNEVKVNAPSAEDTFHILMCIRNLYEQHHHIT
                     LPDNVLKAAVDYSIQYIPQRSLPDKAIDLLDMTAAHLAAQHPVTDLKTLETEIAKQKES
                     QEKAVAKEDFEKALAAKTRIETLQKQIEQHNQSQNVTATVNDIAESVERLTGIPVSNMG
                     TNDLERLKGISSRLKSHVIGQDEAVAAVARAIRRNRAGFDDGNRPIGSFLFVGPTGVGK
                     TELAKQLALDLFGSKDAIIRLDMSEYNDRTAVSKLIGTTAGYVGYDDNNNTLTERVRRN
                     PYAIVLLDEIEKADPQIITLLLQVLDDGRLTDGQGNTINFKNTVIIATSNAGFSQQDTE
                     TSESNIMDRIAPYFRPEFLNRFNSIIKFNHLQKENLEEIVDLMLAEVNQTTAKKGISLT
                     IADDAKAHLIDLGYNHAMGARPLRRIIEQEIRDRITDYYLDHPEVKKLQAILKEGQLVI
                     RQNDQ"
     misc_feature    28139..28152
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 22.77"
                     /tool="antismash"
     gene            28386..29069
                     /gene="rpiA"
                     /locus_tag="ETT68_RS03860"
                     /old_locus_tag="ETT68_03855"
     CDS             28386..29069
                     /EC_number="5.3.1.6"
                     /GO_function="GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /gene="rpiA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881270.1"
                     /locus_tag="ETT68_RS03860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT68_03855"
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="WP_009881270.1"
                     /transl_table=11
                     /translation="MEALKKIAGVTAAQYVTDGMTIGLGTGSTAYYFVEEIGRRVKQEG
                     LQVVGVTTSSVTSKQAEGLGIPLKSIDDIDSIDLTVDGADEVDKDFNGIKGGGAALLME
                     KIVATPTKEYIWVVDASKMVEHLGAFKLPVEVVQYGADRLFRVFEKAGYKPSFRMKGDS
                     RLVTDMQNYIIDLDLGCIKDPVAFGHLLDGTVGVVEHGLFNGMVDKVIVASKDGVTVLE
                     APKAG"
     gene            29146..30357
                     /locus_tag="ETT68_RS03865"
                     /old_locus_tag="ETT68_03860"
     CDS             29146..30357
                     /EC_number="5.4.2.7"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008973 - phosphopentomutase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009117 - nucleotide metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184417.1"
                     /locus_tag="ETT68_RS03865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT68_03860"
                     /product="phosphopentomutase"
                     /protein_id="WP_109991862.1"
                     /transl_table=11
                     /translation="MSKFNRIHLVVLDSVGVGAAPDADKFFNAGVADTDSDTLGHISET
                     AGLSVPNMAKIGLGNISRPIPLKTIPTEDNPTGYVTKLEEVSLGKDTMTGHWEIMGLNI
                     TEPFDTFWNGFPEEILTKIEEFSGRKIIREANKPYSGTAVIDDFGPRQMETGELIVYTS
                     ADPVLQIAAHEDIIPVEELYKICEYARSITLERPALLGRIIARPYVGEPGNFTRTANRH
                     DYAVSPFQDTVLNKLADAGVPTYAVGKINDIFNGSGITNDMGHNKSNSHGIDTLIKTLQ
                     LPEFTKGFSFTNLVDFDANFGHRRDPEGYRDCLHEFDNRLPEIFANMKEDDLLLITADH
                     GNDPTYAGTDHTREYIPLLAYSASFTGNGLIPQGHFADISATVAENFGVDTAMIGESFL
                     GHLK"
     gene            30373..30813
                     /gene="arsC"
                     /locus_tag="ETT68_RS03870"
                     /old_locus_tag="ETT68_03865"
     CDS             30373..30813
                     /EC_number="1.20.4.1"
                     /GO_function="GO:0008794 - arsenate reductase
                     (glutaredoxin) activity [Evidence IEA]"
                     /GO_process="GO:0046685 - response to arsenic-containing
                     substance [Evidence IEA]"
                     /codon_start=1
                     /gene="arsC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922177.1"
                     /locus_tag="ETT68_RS03870"
                     /note="This arsenate reductase requires both glutathione
                     and glutaredoxin to convert arsenate to arsenite, after
                     which the efflux transporter formed by ArsA and ArsB can
                     extrude the arsenite from the cell, providing resistance.;
                     This arsenate reductase requires both glutathione and
                     glutaredoxin to convert arsenate to arsenite, after which
                     the efflux transporter formed by ArsA and ArsB can extrude
                     the arsenite from the cell, providing resistance; Derived
                     by automated computational analysis using gene prediction
                     method: Protein Homology."
                     /old_locus_tag="ETT68_03865"
                     /product="arsenate reductase (glutaredoxin)"
                     /protein_id="WP_109991861.1"
                     /transl_table=11
                     /translation="MEEITIYHNPNCGTSRNVLAMIRHAGIEPTIIEYLQTPPNRETLI
                     ELLQSMAISARELLRTNVPEFEAHGLANQAVAKKDVINAMLTDPILINRPIVVTRKGVK
                     LCRPSETLLDILPVPLPSPYMKEDGESVNPIEVKGEKDVIDD"
     gene            30797..31606
                     /locus_tag="ETT68_RS03875"
                     /old_locus_tag="ETT68_03870"
     CDS             30797..31606
                     /EC_number="2.4.2.1"
                     /GO_function="GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647060.1"
                     /locus_tag="ETT68_RS03875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT68_03870"
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="WP_109991860.1"
                     /transl_table=11
                     /translation="MSLMTKINETKDFLVTKGIETPEFGLILGSGLGELAEEVENAIVI
                     DYADIPNWGKSTVVGHAGKLVYGDLAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKALG
                     CEGVLVTNAAGGIGYGPGTLMAITDHINMTGNNPLIGENLDEFGPRFPDMSDAYTKVYR
                     DKAYEVAEKMNIKLEDGVYMGLTGPTYETPAEIRAFKVLGADAVGMSTVPEVIVAAHSG
                     LKVLGISAITNFAAGFQSELNHEEVVEVTQHIKEDFKGLVKAILAEL"
     misc_feature    complement(31806..31819)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.2"
                     /tool="antismash"
     gene            32124..32837
                     /gene="deoD"
                     /locus_tag="ETT68_RS03880"
                     /old_locus_tag="ETT68_03875"
     CDS             32124..32837
                     /EC_number="2.4.2.1"
                     /GO_function="GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene="deoD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984928.1"
                     /locus_tag="ETT68_RS03880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT68_03875"
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="WP_002990147.1"
                     /transl_table=11
                     /translation="MSIHISAKKGDIADKILLPGDPLRAKFIAENFLEDAVCFNEVRNM
                     FGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKTLIRVGTAGAIDPEVHVRELV
                     LAQAAATNSNIIRNDFPEFDFPQIADFGLLDKAYHIAREMGVTTHVGNVLSSDVFYTNM
                     PERNMALGKLGVKAIEMEAAALYYLAAQHHVKALGIMTISDNLNDPTEDTTAEERQTTF
                     TDMMKVGLETLIAND"
     gene            32830..33618
                     /locus_tag="ETT68_RS03885"
                     /old_locus_tag="ETT68_03880"
     CDS             32830..33618
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984926.1"
                     /locus_tag="ETT68_RS03885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT68_03880"
                     /product="hypothetical protein"
                     /protein_id="WP_002994010.1"
                     /transl_table=11
                     /translation="MTNNQTLDILLDVYAYNHAFRIAKALPNIPKTALYLLEMLKERRE
                     LNLAFLAEHAAENRTIEDQYHCSLWLNQSLEDEQIANYILDLEVKVKNGAIIDFVRSVS
                     PILYRLFLRLITSEIPNFKAYIFDTKNDQYDTWHFQAMLESDHEVFKAYLSQKQSRNVT
                     TKSLADMLTLTSLPQEIKDLVFLLRHFEKAVRNPLAHLIKPFDEEELHRTTHFSSQAFL
                     ENIITLATFSGVIYRREPFYFDDMNAIIKKELSLWRQSIV"
     gene            complement(33698..34603)
                     /locus_tag="ETT68_RS03890"
                     /old_locus_tag="ETT68_03885"
     CDS             complement(33698..34603)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284709.1"
                     /locus_tag="ETT68_RS03890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT68_03885"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_002984924.1"
                     /transl_table=11
                     /translation="MRIQQLHYIIKIVECGSMNEAAKQLFITQPSLSNAVKDLEMEMGI
                     TIFNRNPKGITLTKDGVEFLSYARQIIEQTSLLEDRYKNHNTGRELFSVSSQHYAFVVN
                     AFVSLLKRTDMTRYELFLRETRTWEIIDDVKNFRSEIGVLFINDYNRDVLTKLFDDNHL
                     TASPLFKAQPHIFVSKSNPLATKSLLSMDDLRDFPYLSYDQGIHNSFYFSEEMMSQMPH
                     NKSIVVSDRATLFNLMIGLDGYTVASGILNSNLNGDQIVAIPLDVPDEIDIVFIKHEKA
                     NLSKMGERFIEYLLEEVTFD"
     gene            34825..35361
                     /locus_tag="ETT68_RS03895"
                     /old_locus_tag="ETT68_03890"
     CDS             34825..35361
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990141.1"
                     /locus_tag="ETT68_RS03895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT68_03890"
                     /product="hypothetical protein"
                     /protein_id="WP_009880718.1"
                     /transl_table=11
                     /translation="MNVTEQNSHQILIQKLLVSIHYLTLFRDELKLVERTPSILGGEFP
                     AHLVQSELGDIVAAIDTLDMQQRLIESTFWYEESAFKLMNKTLDIVDNWIKGVDHLIDL
                     CQSKEVFQIIIGDKRIRVFGVLSDVFSSLKVSALSLKEAPIPDLLYEHIQRVNLEEEAF
                     IKYYQGPKVPTGEFE"
     gene            35638..36330
                     /gene="pyrF"
                     /locus_tag="ETT68_RS03900"
                     /old_locus_tag="ETT68_03895"
     CDS             35638..36330
                     /EC_number="4.1.1.23"
                     /GO_function="GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA]"
                     /GO_process="GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="pyrF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984921.1"
                     /locus_tag="ETT68_RS03900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT68_03895"
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="WP_011184421.1"
                     /transl_table=11
                     /translation="MKEERPIIALDFSSFEETKAFLDLFPAEEKLYVKIGMELYYAQGP
                     DIVRYIKSLGHNVFLDLKLHDIPNTVRAAMAVLKELDIDMATVHAAGGVEMLKAAREGL
                     GQGPTLIAVTQLTSTSEDQMRGDQNIQTSLLESVLHYSKGAAKAQLDGVVCSAQEVEAI
                     KAVTPTGFTCLTPGIRPKGSNIGDQKRVMTPNQARRIGSDYIVVGRPITQAKDPVAAYQ
                     AIKAEWAG"
     gene            36388..37017
                     /gene="pyrE"
                     /locus_tag="ETT68_RS03905"
                     /old_locus_tag="ETT68_03900"
     CDS             36388..37017
                     /EC_number="2.4.2.10"
                     /GO_function="GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pyrE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922180.1"
                     /locus_tag="ETT68_RS03905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT68_03900"
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="WP_002984920.1"
                     /transl_table=11
                     /translation="MTLASQIATQLLDIKAVYLKPEDPFTWASGIKSPIYTDNRVTLSY
                     PKTRDLIENGFVETIRAHFPEVEVIAGTATAGIPHGAIIADKMTLPFAYIRSKPKDHGA
                     GNQIEGRVLKGQKMVIIEDLISTGGSVLDAAAAASREGADVLGVVAIFTYELPKASQNF
                     KEAGIKLITLSNYTELIAVAKLQGYITNDGLHLLKKFKEDQVNWQQ"
     gene            37214..38668
                     /locus_tag="ETT68_RS03910"
                     /old_locus_tag="ETT68_03905"
     CDS             37214..38668
                     /EC_number="3.5.1.4"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1105: amidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407508.1"
                     /locus_tag="ETT68_RS03910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT68_03905"
                     /product="amidase"
                     /protein_id="WP_002994017.1"
                     /transl_table=11
                     /translation="MTYQDATAMAIAVQTGQTTPLELVTQAIYKAKKLNPTLNAITSER
                     FEAALEEAKQRDFSGLPFAGVPLFLKDLGQELKGHSSTSGSRLFKEYQATKTDLFVKRL
                     EALGFIILGRSNTPEFGFKNISDSSLHGPVNLPKDNTRNAGGSSGGAAALVSSGISALA
                     TASDGGGSIRIPASFNGLIGLKPSRGRMPVGPGSYRSWQGASVHFALTKSVRDTRNLLY
                     YLQMEQMESPFPLATLTKDSIYQSLQRPLTIAFYQRLSDGSPVSLDTAKALRQAVTWLR
                     EQGHQLVELEEFPVNMTEVIRHYYIMNSVETAAMFADIEDTFGRPMTKDDMETMTWAIY
                     QSGKDIPAWRYSQVLQKWDTYSATMASFHETYDLLLTFTTNTPAPKHGELVPDSKLMAN
                     LAQAEIFSSEEQFNLVETMFGKSLAINPYTALPNLTGQPAISLPTYETKEGLPMGIQLI
                     AAKGREDLLLGIAEQFEAAGLLKIPQ"
     gene            38786..39649
                     /locus_tag="ETT68_RS03915"
                     /old_locus_tag="ETT68_03910"
     CDS             38786..39649
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061079.1"
                     /locus_tag="ETT68_RS03915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT68_03910"
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="WP_012560627.1"
                     /transl_table=11
                     /translation="MKKSVTLLSIGLASLLLAACAPHKSQKSSWDTIKEKGVLKVATPG
                     TYQPTSFYNDNNELVGYEVDMVKEIGKRLNIKVKFVETGFDQAFTSVDSGRVDISLNNF
                     DITPKRQKKYNISTPYKYGVGGMIVRADGSSNMVKKDLSDWKGKKAAGASGTEYMKVAQ
                     KQGAELVTYDNVTGDVYLNDVANGRTDFIPNDYPAQKLFVDYMLSQNPNLNVKMSDVQY
                     NPTEQGIVMNKKDDSLKKKIDAVIKDMIKDGSLKKISETYYAGQDLTKPFGKDKKIPVI
                     DTKDVN"
     gene            39678..40328
                     /locus_tag="ETT68_RS03920"
                     /old_locus_tag="ETT68_03915"
     CDS             39678..40328
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057640.1"
                     /locus_tag="ETT68_RS03920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT68_03915"
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_003061805.1"
                     /transl_table=11
                     /translation="MINIPLMKDSLGFVLSGLPYTLGISLLSFFTGLFLGLGLALLGRS
                     RQPLIHYLVRAYISIMRGVPMIVVLFVLYFGLPYYGLELPALLCAYLGFSMVSAAYISE
                     VFRSSIEAIDKGQWEAAKALGLPYALMVKKIILPQAFRIAVPPLGNVIIDMVKSSSLAA
                     MITVPDIFQNAKIIGGREWDYMSMYILVAFIYWLIAFLLERYQEFLENKLALV"
     gene            40461..41114
                     /locus_tag="ETT68_RS03925"
                     /old_locus_tag="ETT68_03920"
     CDS             40461..41114
                     /EC_number="3.2.2.27"
                     /GO_function="GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767071.1"
                     /locus_tag="ETT68_RS03925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETT68_03920"
                     /product="uracil-DNA glycosylase"
                     /protein_id="WP_002984913.1"
                     /transl_table=11
                     /translation="MAHSIWHEKIKSFLPEHYYGRINHFLDEAYASGLVYPPRENVFKA
                     LQVTPLEETKVLILGQDPYHGPKQAQGLSFSVPEEISAPPSLINILKELADDIGPRDHH
                     DLSTWASQGVLLLNACLTVPAGQANGHAGLIWEPFTDAVIKVLNEKDSPVVFILWGAYA
                     RKKKAFITNPKHHIIESPHPSPLSSYRGFFGSKPFSRTNAILEKEGMTGVDWLK"
ORIGIN
        1 ttagaagacg atggacaagg gaatctttat caaattgatg ctgcttttcg ttcctatggg
       61 agcctgacag cttgtttttt agattacgca agagttttga atgatccact ttatgacaaa
      121 acccacaaaa agttttggtc tcattatcaa gatgctactg caaccttaac aggcacttac
      181 gccactgata caacttacca taccaaatta aatgaattga ttgaatggta tcaactcact
      241 aattttgatg gtctaatgaa atagttatcc acaattttaa aaaaaatcag aagaaatatg
      301 tcgatttcaa gacaaaagtt atcaatctca ttaaattatc tgtggaaaag ttaatttaaa
      361 cgttcgtgtg ctataataga aacatagaaa atgaataaaa aaggatatgt gaataatgac
      421 aaaaaagaaa ggtaagcttg tacttatcag tctttttgtt ctagcagctt gtttaggagc
      481 ttatagtgca atgagacaat ctcataaaac ttcaaacgtg tcagctgaga ctatcgccag
      541 ttcttcaacc cgacatttta ttgatgaaat tggtccaact gctagtacta ttggtcaaga
      601 acgtgatctt tatgcgtctg ttatgatagc acaagcgatt ttagaatcaa gtaatggtaa
      661 atcaagtcta agtcaagcac cctatcataa cttctttggc atcaaagggg cctataatgg
      721 ttcgtcagtt accatgtcaa cttgggaaga tgatggtaat ggcaatacct atacgattga
      781 tcaagccttt agagcttatc caagtattgc agactccctt aatgactatg cggacttgct
      841 aagttctagc acttatatag gtgctagaaa atcaaacacg ctatcgtatc aagatgctac
      901 agcagctcta actggcttat acgctacaga caccagttat aacttaaaac taaataatat
      961 tattgcaacc tatggtttga cggcttatga tgttgctaat agctcagctc aagaaactgg
     1021 tctagcaact tcgggttatg tttggaatga gtatcgtcgt aattacactg atgcggagac
     1081 cctagcagtt gatgaggctt gggctaaacg catgacttat taatgtaaca ctaacaacaa
     1141 tctgcttgca ctgaccccaa aaaagctgga tactctattt taagtaaagg atttagttct
     1201 gtattgtaca gaactaaatc cttttagttt tactttgata tgtttatcgt tgtaataatc
     1261 aatgccgttt gtaatcgctt gttctaagtc ttctagtgat ttatagttat tctcataacc
     1321 atagaacatt tctgacttta agatgccaaa gaaagattcc atcatgccat tgtcaggact
     1381 gtttctttta cgtgacatag acggacgaat tcctttagag tttaggaaat gatgataata
     1441 gttgtgttga tattgccaac cttgatcact ctatcatata gttccatcat agcatttatt
     1501 tggagatgtc tttttccatt attggtttaa tgtgatttaa gcaaggttat tagctaaact
     1561 taatgccaga caaaaacacc ccaattatta gattttttgt ctaacttttg gggcgcaatt
     1621 caatctgagc agttttagat ttggtatcaa tgttattata agtcaattga tcatatttat
     1681 ccaaagcttt tagcttattt agtccaaaga taaatatcaa aatggctgaa atctttcatg
     1741 tttatagtct tattgtcttt atatttttta aagacatcag atctggtgct attgggtttt
     1801 gcatcatata aattgatttt ttcatgtttc ctatttttac tgtgaatttc taaactcccc
     1861 ccttatataa ggagacttag tcaaataaat ttcttttgat tccatcaaaa attttcttat
     1921 tttaaaatcg aactcttgaa tcgtaacaat atccttatcg atttttatag gatttattaa
     1981 tgtttttgct gttgcccatc tataaaaaaa ttccctcaaa gtatttcttc ataccaatag
     2041 atgcattact atcagagtct gttacataaa tagctttaag gttcccgtta gaatcaaagt
     2101 cagctcccca caggtttata acatggttga tgcgtacgtt agcgtaggtg tgtgataggc
     2161 ctagagcctt gccttcggtt aactctttct taatgagatc actgatttct ttgagagttt
     2221 tttctttaaa atcatgacga cttgtcaata gcttactttg atcacctctt gtaaatacgg
     2281 cgtcaaaaat accacctcgg cgatctttct cttgataggt tctattgaca tcagtagtct
     2341 gtgtcttata aacatttaag taatagccat tgataaacat atctaaaaca agatcaggca
     2401 taactccaat tcggcgtgct gacaaaccgg ggaaagcttt atctcggaaa taattaaaaa
     2461 gctcgctatt tgtttggtca cctttagtat taataacttt tcttacatcc aataattctt
     2521 gatcaccaaa catgattttt tgtttatctg ggtgtttttt tagatatgct tcaatttttt
     2581 ctttgttttg atcgaaccac cagtgaagca tattccctgc tgtggcagcc ccgcaaagaa
     2641 gatcgtcttt tccattgaat gttttggtaa tatcatacca tccttggtta gcaacataag
     2701 gagcgcgaaa aacatcttcg ccttgagtga attttgctgg aggagtaact cctttggtcc
     2761 aaacggaagt aacaccttat catgttactt ccgaatatct aatctcttga ttagcagaaa
     2821 aactatctgc tataacacca cgatctactg atagagcaaa taaagtcact gctgccaata
     2881 ctgcagctga agttgaatac catctttttc tcataagagt acctttttct atacaatttt
     2941 attataaaaa gattatatca tatagacatc tattgttgca attttttaaa ataatattta
     3001 attttttaaa taatttttaa taaacgtaaa caagcgattg acaatggaga tatcacaaga
     3061 gacacagtag tggttgtgct taaaaatgga cggttttttg atgatatgtt gctgcatgag
     3121 gaagtgagca ataggagagc tgtgatagaa gaaagagagg aagaagcgtt gatgaaatta
     3181 gacaaataaa aaaaagacct catccagaag aggtcgtggt ataactgggg acgataggtt
     3241 caattgataa aaaatcttgt tagcttacga tctatgttgt tttgaatgcc tttaactcaa
     3301 catcgttaat ggattttgag ataaaaaaat aaatccaata gtctggtact ttcctatttt
     3361 ttgtctgtta aaacgttttt attttataat ggataaaagg agaagaaggg cggagcgatg
     3421 attaagcccg atgggtttaa gtatgggtta gttggagagg ttttgaggcg gattgaacgc
     3481 ctaggattta cgtttgagcg actagagcta agacaagcta gttcgaaata cttggctaag
     3541 catgatgagg ccttgatgat aaaccttttt atccttgact taaaacttac ctgatcagtg
     3601 gttctgtttt aattgaggtg cagtacaaga ccactaacgg gtgttttttt gatataatgt
     3661 cagtataagg acgactaaat ataaataggt gaaaaaatag atatctgttc gagagatagc
     3721 actgtttaaa acgttatgcg aaaatagtag tttaggggct actttaataa tctacaaatc
     3781 tatgctataa tgagtcatat cgacatcaag gagaatgaat atatgcaatt agttcgtgaa
     3841 aaagaatttg tcaatcaata ccactatgat gctagaaatt tagagtggga aaaagaaaac
     3901 ggaacaccag agaccaattt tgaagtgact tttcagttga ttgataaaga tgagcagcaa
     3961 aaagaaacag taattgtatc tgtattgcaa tttgttattg tcaaagaaga atttgttatt
     4021 agtggggtca tctcacaaat ggttcgcatt ttagatcgtt tagtggataa accaagcgaa
     4081 tttacgcaag aggaagttga atccttagct gctcctttgc tagacatggt taagcgattg
     4141 acttatgaag tcacagaaat tgccttggat cgtccaggta ttcatttgga gtttaaaaat
     4201 taatgaaatt agcagtaatt actgacagta cagcaacact accaacagat ctgaaacaag
     4261 ataaagctat ttttagcctt gatataccag ttatcattga cgatgagacc tattttgaag
     4321 gtcgaaattt gagtatagat gatttttatc aaaagatggc tgactcccga aatcttccca
     4381 agacaagtca gccaagttta tctgaactag ataatctttt aggacttttg tcttctaagg
     4441 gttatacaca cgttattggc ttgttcttag ctggaggaat ctcaggcttt tggcaaaata
     4501 ttcaattttt agctgaagaa catcctgaga ttgaaatggc atttccagac agtaagatca
     4561 catctgctcc tttaggtagt atggtaaaaa atgtgctaga ttggtcacgt caaggaatga
     4621 catttcaagc tattttaaac aagctgcaag aacagattga tgggacgaca gcctttatta
     4681 tggttgatga ccttaatcat ctggttaaag gcggacgcct gtcaaatggg tccgctcttc
     4741 ttggaaatct tttgagtatt aaacctattt tacgctttga tgaagaggga aaaatcgttg
     4801 tttatgaaaa agtgagaaca gaaaagaaag ccatgaaacg cttggttgag attttaaatg
     4861 acttgatagc agacggtcag tataatgtgt ctattattca ctcaaaagca caagacaaag
     4921 ctgattattt gaaacgactc ttacaagaca gtggttatca atatgacatt gaagaggttc
     4981 attttggagc ggtgattgct actcatttag gagaaggagc cattgcattt ggcgtaacac
     5041 cgaggcttta attgtcgatt agaaaaaata gttaattgca agaatcacta aaacaataac
     5101 aaaatgtgat agaacccaag tagcctaatc acactttaga ttgggctagt tggatgatag
     5161 gttagaaaac aacgtatgaa attaatgaca atgccttctg agtttcagaa ggctttaccc
     5221 atattgacta aaataaaaga agctggttat gaagcctatt ttgtgggagg aagcgtcaga
     5281 gatgttttac tcgagcgtcc cattcatgat gtagatattg caactagttc ctatcctgaa
     5341 gagactaaag cgatttttaa cagaactgtc gatgttggca ttgaacatgg tacagtgctc
     5401 gtgcttgaaa atggcggtga gtatgaaatc acaaccttta ggacagaaga tgtctatgtt
     5461 gactatcgcc gtcctagtca ggtttctttt gtgcgctctt tagaggaaga cttaaaacga
     5521 agagacttta ccgtcaatgc cttggccttg gatgaaaatg gtcaagttat tgataaattt
     5581 agaggactca ttgatttaaa gcaaaaacgg ttacgagcag tgggtaaagc agaggaacgt
     5641 tttgaagaag atgcactacg cattatgaga ggctttcgat ttgcggcgag tctggatttt
     5701 gacattgaag ctgcaacttt tgaagctatg aggagccatt cacctctatt ggaaaagatt
     5761 tctgtggaac gttcttttac tgaatttgat aaattattga cggcaccgca ctggcgaaaa
     5821 gggatttctg ccatgattgc ttgtcaggct tatgactatt taccaggctt gaagcagcag
     5881 gaagcaggct taaatcatct gatagtttct ttgaaagata actttacctt tagtgatcat
     5941 caccaagctt gggcttatgt gatgattagt ttagccattg aggatcctaa aagcttccta
     6001 aaagcatgga agacttcaaa tgattttcag cgttatgtca caaagttgat tgctctttat
     6061 agaattcgtc aggaaagatc ttttgaaaaa ttggatattt accagtacgg caagaaaatg
     6121 gcaagtctag tggaaggcct ccgaaaagct caaagcttat ccgttgacat ggatcatatt
     6181 aatactttag atcaggcact ggttattcat gacaaacacg atatcgtcct taatggttct
     6241 cacctgatta aggattttgg gatgaaacca ggtcctcagc tagggcttat gcttgagaaa
     6301 gttgaattag cgattgtaga ggggcgccta gataatgatt tcactacaat tgaagcattt
     6361 gttagagagg aattagcaac atgagccatt ttttggtgga gaaattaaca aaaacggtgg
     6421 gagataagac cgtctttcaa gatatttcct ttattattca tgactttgac cgtattggga
     6481 ttattggggt taatggaaca ggaaaaacaa ctcttttaga tgtgttgtcg ggaaggcttg
     6541 gttttgacgg agaccattca ccattttcta aagccaatga ttacaaaatc gcttacttaa
     6601 cacaagatcc tgaatttaac gatgcagctt ctgttttaga tacggtattg tcatctgatg
     6661 ttaaggcgat tcggctgatt cgtcagtatg aactattgat ggcgaattat actgaggata
     6721 aacaagaaag cttagagtcc ctcatgtctg aaatggatcg cttagatgct tggtctattg
     6781 aaagtgatgt caaaacagtc ctatcaaaat taggcatcac ggatttggaa caaaaagtgg
     6841 gagacctatc aggtggtatg agaagacgtg tccagttagc tcaagtattg ctaggagctg
     6901 ctgacttact cttgttggat gagccgacca accatctcga tattgacacc atcgcttggt
     6961 taacaaccta tctcaagaca gctaaaaaaa ccgtcctttt tattacccat gaccgttatt
     7021 tccttgatca tgtggctacc cgtatttttg aattggataa agcgggactg acagaatatc
     7081 aaggcaatta ccaagactat gtgcgcttaa aagcagaaca agacgaacga gatgctgcta
     7141 atttacacaa gaagaagcaa ctctataaac aagaattagc ttggatgagg acgcagccac
     7201 aggcgcgtgc aaccaaacag caggctagaa tcaatcgttt cactgacttg aaaaaagaag
     7261 ttcaccaaga cagttctgca gataaattgg agatggcttt cgaaacgagc cgaattggga
     7321 agaaggtgat tcactttgaa gacctttctt ttgcttatgg cgaccgacag ttgattaagg
     7381 attttaactt gattattcaa aataaagatc gtattggaat tgttggagat aacggcgtcg
     7441 gaaaatctac cctgttaaat atcattaacg gtgatctcaa accaacttct gggaagcttg
     7501 atattggaga tactattcgt gtaggttatt tctctcagca gctcaaagat atggatgaga
     7561 ccaaacgggt cattaattac cttcaagaag tggctgatga ggttaaaaca agcgtgggaa
     7621 caacgagtat cagtgagctt ttagagcaat ttctttttcc gagatcaagt catggcacgc
     7681 tgattgctaa attatctggt ggggagaaaa aacggctcta cttgctaaaa ctgctcattg
     7741 aaaagccaaa tgttcttctc cttgatgagc caacaaatga tttagacatt gccaccttga
     7801 cggtcttaga aaacttttta gctaactttg caggaccagt cattacggtt agtcacgatc
     7861 gttatttcct agacaaagta gccactaaga ttttagcttt tgaagaaggc gatattcgta
     7921 ttttttatgg caattacagt gattaccttg atgaaaaagc ttttgaaaaa gaaacagttg
     7981 aggcagactt agctaaagca atagtcactg aagaagtgcc acttcctccg aaagaggaga
     8041 aaaagcgcat gtcctacctt gaaaaacaag aatgggctca gatagaagat aaaatagcaa
     8101 ctattgaggc taatattgaa gaaattgaaa accaaatgtt aactgtagtt agtgattatg
     8161 gccagttagc tcaattacaa aaggaactcg atcagcgcaa taatgattta ttattggcgt
     8221 atgaacggtt tgagtatttg agtggactag acatataagt atactatggt aatgttatgt
     8281 ttataataaa caagtgataa tagaaaagaa gtgctcttgc actgatcccc aaaagttggc
     8341 tactctattt gaagtaaagg atttagttct gtgttgtaga ggactaagtc cttttcgttt
     8401 tattttgata cgtttattgt tgcaataatc gatgataata gtaggtagaa cgagtcaatt
     8461 tagccgttct taaaagaaaa tctaatcaga actcgtcttt gtccattctt tataatggtt
     8521 ttttgtcttc ttctttgcag agatgcttct ttcaaacgga gttccctcgg tttttttagc
     8581 gctaaatatc tagcttatct tcatagctta atgtcataca aaaacacccc aaacgttaga
     8641 tttttttatc taacgtttgg ggtgtagttt acattatggc gcttcttttc tattattacg
     8701 tgaggaaaaa tcaagtaaaa aagttaagtc aactgaaaaa cttgacagaa atattcagaa
     8761 aatttataat actaactatt aacaacatat cagctattaa agcatttcaa acagcaggtg
     8821 ttttatttgg acctgttaag gctgcaaatg caagagaaag cagtatctgg tttgaaaatc
     8881 tcacaaagca ataactatct ctcttagaca cttgaagaag cagacagtaa actcgataat
     8941 attgtgatga gaacttagca acaatctgct gatgcaggtc aatttttatt tggtactcat
     9001 attgtagaat ttcataaagt tgcccaagat atcttgaaat aaggaatcat ctgatgtttt
     9061 aaacagatga tactaagtct atcatatggt gataatagtc cattgaacat gtagtttatg
     9121 aattaaaaaa agtttaagga gataagaatg attagagaaa tcataacaga tcatttttta
     9181 ttacagcaaa aagcacaagt cgccaagaaa gaagatctat ggattggcca agatttacaa
     9241 gataccttag ccttttatag gcaggaatgt cttgggatgg ctgccaatat gattggtgaa
     9301 caaaaacgca ttgttattgt gagtatggga tttattgatt tggtgatgtt taatcctgtg
     9361 atggtttcta aaaagggaat ttaccaaact aaagaatctt gtttgtcatt atctggctat
     9421 cgcaaaacac agcggtatga taagattact gttgagtatt tggaccataa ttggcgacca
     9481 aagcgtttaa acttaacagg cctaactgct caaatatgcc agcacgaatt agatcatcta
     9541 gaaggtattt taatttaaca aaaaacctag agtaggacac tttaggtttt tttggcgaaa
     9601 atgcctgatt atataaggat gatcaattac tagtaaacgc taggattttc tttttttaat
     9661 gaaagcgttt agcccaccta agcttatcaa ggcaaggatt gtcataatag gagacatttt
     9721 ataattgtcc cctgttattg gaagagtgga attagagata gtatttttgt ttgttgttgt
     9781 ctcttttttg ccaaagctgt tattagtgtt ttcagtagaa gtcaaaaggt ctgaaatgat
     9841 ttcactagac actatattgc catcacgatt tctaaaaacc ttactaatga taatgatact
     9901 gtgtttgcca gcactattaa tttttgttga gctttcaagg tttgaagtta cataattttt
     9961 aacccctttg atagtagcat taacagtttt acctgatgct tgtaaatttg tgatatatgt
    10021 gatgaaagct tcagtatctg tgttaatagc tccgattaat ttagcttttt taaatgctga
    10081 aaagccatca ccgccaccat aaagaaagtc gttgacaaca acggtgtaag tagttgttaa
    10141 gttaatttct tcaccattgt ctttataaac cttaactatc ttgaaggggg tatcagagtt
    10201 cttaggatca ttatctgtat aagtgtatgt taaacctgac atttgaagaa aataggtctg
    10261 gttttcatcg tattgctgat ttaggacatc gtaaatgtgt tgaccagtca tttgaatgac
    10321 ttgaaggata ttaccaaatg gttgtacagc ctgtgcagct ccccaggtga tggtccggtc
    10381 atttttgaca actaggtcac ttcgaatacc accattattg gtcatagcaa agtcaacagt
    10441 tggaaaagtt ttcttagcaa tagtaagctg agccgttgtt actaagttac cgacaggaga
    10501 ttctttatca atattttctg ttttagaaat agttgaagaa ttagttgcag ttccgatttt
    10561 tcgttcagta actgttttaa caatatcatt agcatgattt attatagctt tgatatctga
    10621 attttctgtt ttgatacctg gtgctacagc aacaacattt gctgatggag ttttaataaa
    10681 atcattggta tcagtatcta gcgtaccacg gacatctgca taagcttttc cttgagagag
    10741 ggcttgaacg atacgtgttt taccgatagt tccattagtg tattgatgat tatgtcctgc
    10801 aaaaataata tcaatactat gttcgggata gatttggttc actttttcca taaccgtagc
    10861 catttcatga tcaacaacac catctttact tgttgcagga atatgagcta aaaccacaat
    10921 agcatgaaca tgttgttctt gcagttcttt agcatatttg gcaatggttt cagctacatc
    10981 taaaaattga tagtgttcat agttttgctt taaaacgaga tttggaatct ctgtagtcac
    11041 aacaccaatg aagccaatct taacgatttt gtcattaatg gctatgtctt ttatagcata
    11101 aggtttccaa ccatagggga tatcattagt ttttttataa tgacgatggt ttgatgcgaa
    11161 gcttcgtgct catattgttt ggtgatatca ttaattgttg attcaggatc aggcgcttga
    11221 cctgtcatga tacggttaaa ttcatctagt ccttcgtcaa attcatgatt accaagagtg
    11281 ccatattcaa atttcatttt gttaaagact tttacagtag gctcatcttg taaaagtgca
    11341 gagttagcag gactggctcc gaccatatct ccagcttgaa cacgtatact tgttccgtct
    11401 tgatttgctt gcttgaagtc tatctcagcg tcatccatat aagcacctaa ttgagcagcc
    11461 gtcccagcat ttggtatttt accacttggt gtgtaagctg ttccggtatt atcaagagcg
    11521 ccgtgaaaat cattgacgcc aaggaattgc acatcaactt gatctgcttg aacatctgta
    11581 actaatagag taaaactagt caggatactc aatacactac tttttaaaat aaaatatttt
    11641 ttcataaaat ctcctaataa gttaaggtaa tcgttataga tcaagtttac tatgattttg
    11701 tttgtaattc aatggtattt ttaaaaaata acgtacaaaa aatatatgaa agcgatttaa
    11761 aaacaaacga tacagatcat ttgcagttat atagttagaa ataaagataa ccgatcattg
    11821 cagagattta agcatttgtt gagaaaattt gttataataa gcgtatgaaa gaaagactag
    11881 aacattattc taccagctct atatatagcg gatttgaagt gtacttgccg ttggtactac
    11941 agacaataac agatgtgatt attgctgaga atatcaaaag caaaaaagaa acagggttta
    12001 aactatacga acactttaca tcccgtatta aatcggaagc ttcgatgatt gaaaaatgtc
    12061 aacgcaaaca gcttcctcta acaagcaaat ctgcgttaaa aatcattaaa gatagtatcg
    12121 gtattcgcat tatttgtggt tttattgatg atatttatcg gatggtagac ttgctcaaaa
    12181 gcattcctgg tatgtcagtt aacactgaaa aagattatat tttaaatgcc aagcctaatg
    12241 gctatagatc atatcatctc attttggaat tagaaacaca ttttccagat attttagggg
    12301 aaaaaaaagg atgttatttt atagaagtgc agttgcgaac cattgctcaa gactcttggg
    12361 ctagcttgga acatcaaatg aagtacaaac atcaagttgc taatgcagaa atgattacaa
    12421 gagagttaaa gcgttgtgca gacgagttgg catcttgtga tgttaccatg caaaccattc
    12481 gtcaattgat tcaagaaacg acggaggaag agtaaccatg aaaattttgt tagctgaaga
    12541 cgaatggcag atgtctaatg ttttgacaac tgccatgact catcaaggtt atgacgttga
    12601 tgtggttttt aacggtcaag aggcaattga taaagccaaa gacaatgcat atgatattat
    12661 gattttagat atcatgatgc cgattaagtc tggcattgag gctttaaagg agattcgcgc
    12721 ttcaggaaat tgctcacata ttattatgct gacggctatg gcagaaatta atgaccgtgt
    12781 taccggacta gatgcgggag ctgatgatta tctgactaaa cctttctcat taaaagaact
    12841 tttagctaga ttaaggtcga tggaaagacg agtagaaagt tttactcctc aggtattaca
    12901 atttgctggt gtcacattaa atattaatga gcaagaattg agtgccggta atgctatacg
    12961 attagcttct aaagaaggta aattaatggc ctttttaatg ttaaatcaag gaaagtactt
    13021 ggatactaaa acactttacc aacatgtttg gtcagaccaa gaagattatg atacttctat
    13081 tgtttgggtt tatatttctt atcttcgtca aaaattatta gctattcaag caaatgtcat
    13141 tattgcaggt gataaagata ctagctattg tttattagaa aaataggagg tgacatgttt
    13201 aatcgtatcc gtattcgttt tatcatgatt gcttctattg ccatttttat tattttaagt
    13261 tcaattgttg gtattattaa cacggcacgc tgttatcaaa gtcaacaaga aattaaccgt
    13321 attttacatt taatttcctc aaataaaggt aaattacctg gcactacgga aagctctaaa
    13381 cgacttggga cgaaactgtc tgaagatagc ctaagccagt ttcggtatta tagtgtcatt
    13441 tttaatgcta atggacatct actttcttct aatactgcta atatttcagc tttagataga
    13501 gaagaagccc aatattttgc tagacttttt gctaagtctg gggaagaaaa aggcagttac
    13561 cgtcaccaag atagtgttta ttcgtacttg attactcagc tgccaaatga agaaaaactg
    13621 gttgtaattt tagatactac cttttatttt cgtagtgtag gagatttatt agctgtttca
    13681 atgatgttgg cctttggagg atttatcttt tttgttgttt tagtgagtct tttttccggt
    13741 atggtcatca aaccttttgt ccaaaattat gagaagcagc gtcgctttat tactaatgca
    13801 ggccacgagt taaaaacacc actagccatt atctcagcca ataatgaatt ggtcgaatta
    13861 atgactggag aatcagaatg gaccaagagt acaagtgatc aggtgaagcg attgacaggc
    13921 ttgattaatc aaatgattac tttggctcgt ttggaggaac agccagatgt ggtattacat
    13981 atggtagact tttcagctat tgctcaagat gcagctgaag attttaagag tctggttttg
    14041 aaagatggta aacgttttga tttgacgatt cagccgaata ttatgattaa agcagaggaa
    14101 aagtcattat ttgaacttgt gacaatttta gttgataatg ccaataaata ttgtgatcct
    14161 aaaggcttgg tcaaggtatc tttaaccact attggaagaa gacgaaaacg agcgaaatta
    14221 gaagtttcta atacctattt ggaaggaaaa tccattgatt acagccgctt ttttgaacgc
    14281 ttttatcgcg aagacgaatc ccataatagc aaagaaaaag gttatggaat tggtttatct
    14341 atggcagaaa gtatggttaa gttatttaaa ggaacgataa ctgtaaatta taaaaacgat
    14401 gctattgttt ttacagtggt gatttgactt aaacattttt cagtaccttt agctagtaat
    14461 aatgtctagg taaaggtaat aaacgatgct taaccagccc atgaggctgg tttttaacgt
    14521 ttaatttagt agaagagtga ttaaagaagg tagtttgaaa taagaaaatt tttgttatga
    14581 tcctaaaaag agtagatagt ctttattgtt aatttcggtg aagaaatgat tttaaaaaga
    14641 tatatcatcg cattttctaa tcatttagtg taaaatagta aggtaaaagt ttagaagaat
    14701 tagtaatgaa aagataaaaa atgaacgaaa acattggata tggtaaggca cacagtaaga
    14761 tcattttgat aggtgagcat gctgttgtgt atggctaccc agctattgct ttgcctttaa
    14821 cagatattga ggtggtttgt catatttttc cagctgataa gccattggtc tttgattttt
    14881 atgatactct atcaacagcc atttatgctg ccttggatta tttgcagcga ctacaagaac
    14941 caattgctta tgagattgtt tcacaagtgc cacaaaagcg tggtatgggg tcttcggcag
    15001 ccgtttctat tgcagctatt agagccgttt tttcttattg tcaagaaccc ctctcggatg
    15061 atttgttgga aattttagtc aacaaggcag aaattattgc ccacaccaat cctagtggtt
    15121 tagatgccaa gacatgcctt agtgaccatg ccattaagtt tatccgaaac attggctttg
    15181 aaactatcga aatcgcctta aatggttatc ttatcattgc agatacaggg attcacggtc
    15241 atacacgtga ggccgtcaat aaggtagcac agtttgagga aacgaatttg ccctatctgg
    15301 ctaaactagg agctttgaca caagcccttg aaagagcgat taaccaaaaa aataaggttg
    15361 ctatcggtca gctcatgaca caagcgcact ctgctttaaa ggccattggc gttagcatca
    15421 gtaaggctga ccaacttgtg gaggctgccc taagggcagg tgctttaggc gctaagatga
    15481 caggcggcgg cttgggtggc tgtatgattg ccctagcaga taccaaagac atggccgaaa
    15541 aaatcagtca cagattaaaa gaagaaggag ccgtaaacac gtggatccaa atgttataac
    15601 cgtaacatcc tatgctaaca ttgctattat caaatattgg ggaaaagaga atcaagctaa
    15661 gatgattcct tcaacctcta gcatttcttt gactttggaa aacatgttca ccacaaccag
    15721 catttccttc ttaccagata ctgcaaccag tgatcagttt tacattaacg gtgtcttgca
    15781 aaatgacgaa gaacatacca aaatttctgc tatcattgac caatttcgcc aacctggtca
    15841 ggcttttgta aagatggaaa ctcaaaataa tatgccaaca gctgcaggtt tatcatcaag
    15901 ttccagtggc ttatcagcct tggttaaagc ctgtgaccaa ctatttaaca cccagctaga
    15961 tcagaaagct ttagctcaaa aggctaagtt cgcctcagga tcatcttctc gttctttttt
    16021 tggcccagtc gctgcttggg acaaagatag tggtgctatt tacaaggttg agactgactt
    16081 gaaaatggcc atgattatgc tggtcttaaa tgctgcgaaa aagccaattt ctagccgaga
    16141 gggcatgaag ttatgccgcg atacctcaac tacatttgat gagtgggtag aacaatcggc
    16201 aatcgattac caacatatgc ttacctatct caaaactaat aattttgaga aagttggtca
    16261 gttaacagaa gctaatgcct tggccatgca tgccacgaca aagacagcca atcctccttt
    16321 ttcttaccta acaaaagagt cttaccaggc tatggaggct gtgaaagaac tgcgtcaaga
    16381 aggttttgct tgttatttta ccatggacgc aggtccaaat gtgaaggtcc tatgtttaga
    16441 aaaagacttg gctcaactgg cagaacgact tggcaagaac taccgtatta tcgtttcaaa
    16501 aacaaaggat ttaccagatg tctaattatt gtgtgcaaac aggtgggaaa ctatacctca
    16561 caggcgaata tgctatctta acaccaggac aaaaagcctt aattcacttt attccactga
    16621 tgatgacagc agaaattagc ccagcagccc atattcaatt agcttcagat atgtttgccc
    16681 ataaagcggg catgacaccc gatgcctctt atgcactgat tcaagcaacg gttaaaacct
    16741 ttgctgacta tctaggacag tcgattgacc aactggagcc attttcccta atcataacag
    16801 gaaaaatgga gcgcgatggc aaaaaatttg gcattggttc aagtggtagc gtcaccctct
    16861 taaccttaaa ggccttatcg gcctattatc agatcacttt aaccccagag ttactcttta
    16921 aactagcggc ttataccttg cttaagcaag gagataatgg gtctatgggg gatattgcct
    16981 gtatcgctta ccagacttta gtcgcctata cctcctttga ccgagaacag gtcagtaact
    17041 ggctgcagac catgccctta aaaaaacttc tcgtcaaaga ttggggttac catatccaag
    17101 tcattcaacc agccctgcct tgtgactttt tggttggctg gactaaaata cctgctattt
    17161 caaggcagat gattcaacaa gtgacagcga gcattacccc agctttctta agaacaagtt
    17221 accagctaac gcaatcagct atggtagctt tgcaagaagg tcataaggaa gaactcaaga
    17281 aaagtttagc aggagcaagt catctcctaa aagagcttca tccagctatc taccatccta
    17341 agctagtaac cttggtagct gcttgtcaga agcaagatgc tgttgctaaa tcttcaggtt
    17401 ctggtggtgg agattgtggc atcgcgcttg cctttaatca ggatgctaga gataccctta
    17461 tttccaaatg gcaagaagct gatatcgcat tactttatca agaaaggtgg ggagagaatg
    17521 actaaccgta aagatgatca catcaaatat gctctcaagt accaatcgcc ttatagtgct
    17581 tttgatgaca tagaactcat acaccattcc ttacctagct atgatttgtc tgatattgat
    17641 ctcagtactc attttgctgg gcaagacttc gactttccct tttacatcaa tgccatgaca
    17701 ggaggaagtc aaaaaggcaa agctgtcaat gaaaaattgg ccaaagtagc agcagcaaca
    17761 gggattgtca tggtgacagg gtcttatagc gctgctttaa aaaatcctaa cgacgattcc
    17821 tatcgtttac atgaggtggc agataacttg aaactagcca cgaatattgg tctagataaa
    17881 cctgtggcgc taggacaaca aacggttcaa gaaatgcagc ccctcttttt acaggttcat
    17941 gtgaatgtga tgcaagagtt gctgatgcca gagggtgagc gcgtctttca tacctggaaa
    18001 aaacacctcg ctgaatacgc tagtcaaata ccagttcctg tcattctcaa agaagttggt
    18061 tttggcatgg atgtcaatag tatcaagcta gcacatgacc taggcattca aacctttgat
    18121 atttcaggta gaggaggaac ttcatttgct tacattgaaa atcaaagagg gggagaccgc
    18181 tcttacttaa acgattgggg acaaaccact gttcagtgct tactgaatgc acaaggactg
    18241 atggaccaag tggaaatttt agcttcgggt ggtgtcagac accccttgga catgattaag
    18301 tgttttgtct taggagcacg tgcagtggga ctctcacgca ccgttttaga attggtcgaa
    18361 aaatacccaa ccgagcgtgt gattgctatc gttaatggct ggaaagaaga attaaaaatc
    18421 attatgtgtg ctcttgactg taaaactatt aaagaattaa agggagtcga ctacttacta
    18481 tatggacgct tgcagcaggt caattaggct tcatcacctc tacaatagtg tcacctacta
    18541 caaagatgat agagcttttt tagaacataa tataaaatat ttataaatac ctcatcaaac
    18601 tcagaataga gtagatgagt aaatagagta tgttatggag actatttcta agacttgtat
    18661 gtatagaaac aaagattaaa cacccatgta aaccaattgt ttacatgggt gtttgcctta
    18721 tattagttgt ttaaatctaa gactgtctta gctgggataa gtaaaaatgt gctttttcta
    18781 gatttattgg tttatcagct agtaaagcat taactaaagg agcaatttcg tcttgggttg
    18841 cccccgccaa aagagctaat gatttcgcat gtagtttcat gtgaccagct tggatgccag
    18901 atgaggtcag agcttttagt gcagcaaagt tttgagctaa ccccacagat gcaatcaatt
    18961 gggctaatgt tttggcatca ggttgattaa gaagatcatg tgcgatagaa acagtagggt
    19021 taagcccgat agatcccccc ttactagcaa taggcatagg gagggtcatt tggccaagca
    19081 gaacttgttt atcttggtca aaatgccact gactaagtcc ttgatagcta ccatttcttg
    19141 aggcataagc atgggcccct gcttcaatag cacgccagtc atttcctgtg gctattacca
    19201 ctgcatcaat accattaaaa atacctttat tatgagtagt agcccggtaa ggatctactt
    19261 gagctagtcg gctggctagc tctatttttt gagctaactg tagagatttt gttttatcgc
    19321 gatctaaaag gcgcacggga atctcacaac tagtagtaac aagcgactct gttgcgtaat
    19381 tagataaaat cgccattaga caatgcccct tagacagtct tgttaaatca ggaacaagag
    19441 cttccatcat agtattgacc atatttgctc ccatagcttc ttgggtatca acagtcagat
    19501 agaaaatcaa aaattctcct ttttcttcca aatgaatggt tctagcgcct ccacctcttt
    19561 taacaatgga aggataagct ttatttgcca atgcaattag cttttttgtt ttatgaagga
    19621 tggcggcttt agcgttatct atttggtcga tatcgtaaag aacaatttga ccaatcattt
    19681 gtcggtttag ggtttgagct ttaaaaccac ctgagcgttt gattagtttt gctgcgaaag
    19741 atgctgcagc aacaacagaa ggttcttctg tgacaaaagg catctgataa gttgagccgt
    19801 tgacaagaaa atcaggagct atgctaaagg gcaaagccaa tcgtcctaag acattttcgg
    19861 tcatttgatt agctgtttgg ataggcaaaa gaacgtctgt tttgagttga tttaagtttt
    19921 cagcattaag tagtttaaat ttttcgataa gttggaggcg ttcttcgaat gttttctttg
    19981 aaaaaccgct ccagttaaga ttagtttttg tcattggtat gatagatcct ttgatgctcc
    20041 ttgatggctg ttagagcaaa ttttccagtt aagtaaatgt caaaattggc attaccatta
    20101 tcatctaatt ggacttgttc gtagaaaagg tcttcgtatt tagaaacgga aagacgtgtt
    20161 cgttgatcca gtaaagcttg tcgattagtc attaacattt tatcgtaccc agcaactaac
    20221 tgaccggaat aaaattcact tacggcaccg gaaccatagc taaaaaaacc aattttatct
    20281 ccagattgta atactttact attttcaagt aaagataaca atcctagata aagtgagcca
    20341 gtataaatat ttccaatttg tttgctataa gtaatagaag cttgaaaggc ttctattagt
    20401 ttttccctgt gttcaggagg tactgtgtta tccataatgt tatttagacc ttttagggct
    20461 aacttgggaa atggaatatg gaaacaaact gcagcaaaat cagataactg aaggttttct
    20521 cttttctgat aagcttgcca cgtggtttct aagcaattga gatattgctt ggtagagtaa
    20581 ataccatcaa cataaggtgt gaaactatag ttaggcctcc aaaagtccat aatatcccta
    20641 gtttgagcca cattatcttt atttagagca agaatacgag ggttagcagt taccaaaaga
    20701 gcaatactac cagagccttg agtcgattcc ccaggagatc ctacaccgta tctagcaata
    20761 tcactagcaa taacaaggac acgagaatct ggcttagaag ccacatgcag tttagcatag
    20821 tctagagcag cagttgcgct atagcaggct tgttttactt caaaggaacg tgcaaaaggc
    20881 tggataccaa ctaagtgatg tacatagata gctgatgcct ttgactgatc agtactcgat
    20941 tcagttgcca aaataaccat atcaatttta gctcgatctt cgtcggttaa gatttgatct
    21001 gctgcagaag cagctaaagt aataatgtct tcagtgattg gtgccacact aaaagactca
    21061 atgagtagcc cttgactaaa ttttgctgga tccacttggc gtgcaagcgc taaatcttcc
    21121 aatttcaaga catattgact ggttgcaaaa ccaatcttat caattccaat tgtcatattt
    21181 gtccttcttt tagttatttt tatagtctta cccattctat cacattttac tgcaaaatta
    21241 gactgataaa gttatttgtt ttatccttta atagttaaaa tgttcatgac cacatgaagt
    21301 ttttcgaatg tttatttatt ctggtatttt ttggtaaaat tagttagaat agtatgaagt
    21361 atgcttacag aaaggttatt agagatgaca aaagctgacc agatttttaa agctaatatt
    21421 caaaaaatta taaacgaagg atcattgagt gagcaagcac gtcctaaata taaagatggt
    21481 cgaacagctc attctaagta tattactggg gcgtttgctg aatatgattt agctaaagga
    21541 gagtttccca tcacaacttt acgacccatt ccaattaaat ctgctataaa ggaattattt
    21601 tggatatatc aagatcagtc taacagttta gatgtgctag aagctaaata taatgttcat
    21661 tattggaatg aatgggaagt tgaccagaca cgtactattg gacaacgtta tggtgctgta
    21721 gtcaaaaaac atgatatcat ctcaaaaata ctaaagcaat tagcagaaaa tccttggaat
    21781 cgtcgtaatg tcatttctct ctgggactat gaagcatttg aggagacaaa agggttgttg
    21841 ccatgtgcct ttcaaatcat gtttgatgtt agacgtgtag gggaagatct ttatttagat
    21901 gctagtttga cgcaacgttc taatgacata ttagttgctc atcacatcaa tgccatgcaa
    21961 tacgttgcct tgcagatgat gattgctaaa cattttggat ggaaaatagg taagttcttt
    22021 tattttgtta acaatttaca tatttatgac aaccaatttg atcaggctca agaattacta
    22081 aaacgacagc cagttgctag tcagcctaag cttgttttaa atgttccaga tgggactaat
    22141 ttctttgata ttaaaccaga tgattttgaa ttacaaaatt atgatccagt gaagcctcag
    22201 ttgcactttg accttgctat ttaaacttta tttagatttt ttgtgagcat tttgttcata
    22261 aatttggtaa aataaataga gtttaaaatg aaggaaataa ttaatgacaa aggaaattat
    22321 tgctatttgg gcagaggatg aagcagggct tattggtgtt gcgggtaagt taccatggta
    22381 tttaccaaaa gagttagaac attttaaaaa gacaacgcta catcaagcaa tcttaatggg
    22441 ccgtgtgact tttgaaggaa tgaattgcaa aagacttcct caacgtcaaa cccttgtcat
    22501 gacaagaaat agagattatc aagtagatga ggtgttgaca atgactagta ttgaaaaagt
    22561 cttggagtgg taccatgcgc aggataaaac actttatatc cttggtggga ataaggtttt
    22621 agaagcgttt aatggttatt ttgatcgtat cataaaaaca gttatccatc atcgttttaa
    22681 aggagatacc taccgaccca atctagattt tagtcatttc acgcaagaaa gccaaacgtt
    22741 ctatgctcga gacgctaaaa atccttatga ttttaccgtt actgctttaa aacacaaata
    22801 gtctgaggag atgataagcg atgcaacgta gtatttttgg agtatttacg gcttttttgt
    22861 gcgtgatttg tgttctttgt gccatcccag cttttaaaaa gaatcgttat ggcttaggaa
    22921 gtctgttctt attaaatgcg tttactaatc tggttaatag tattcacgcc ttctatggta
    22981 cattgttttg agatgcgact tgcaaagaca gcactggtga agatttagct atcaagcaag
    23041 aatcaccaaa aaccaataca acacattgac taatattaaa attcagtaaa agataagaga
    23101 aagtaagaga attataagaa atggcaggaa gtagaactaa cgatattaaa gtatactgtt
    23161 cattttgtgg taaaagccag gatgacgtta aaaaaattat cgcaggaaat aatgttttca
    23221 tctgcaatga atgcgtagct ttatcacaag aaattataaa agaagaattg gctgaagaag
    23281 tccttgccga tttgacagaa gttccaaaac caaaagagct ccttgatgtt ttaaatcaat
    23341 atgtggttgg tcaagatcgt gctaaacgtg ctttatcagt tgctgtgtac aatcattata
    23401 agcgtgtctc gtttacagaa agtcgtgatg acgatgatgt ggatttacaa aagtccaaca
    23461 ttttgatgat tggaccaaca ggttcaggaa aaaccttctt agcacaaact ctggctaaaa
    23521 gcctcaatgt accatttgct attgcagatg caacttcttt gactgaagca gggtatgttg
    23581 gagaagatgt ggaaaatatt ttactcaaac tgattcaggc tgctgactat aatgtcgaac
    23641 gagcagagcg tggtattatt tatgttgatg aaatagataa gattgctaaa aaaggtgaga
    23701 acgtatctat cacacgtgat gtatctggtg aaggtgtaca gcaagccctt cttaaaatta
    23761 ttgaaggtac ggtagcaagt gttcccccac aaggtgggcg gaagcaccct aatcaagaaa
    23821 tgatccaaat tgatacaaaa aatatcttgt ttattgttgg cggggctttt gatggcatcg
    23881 aggagattgt caaacaacgt ttaggtgaaa aagttattgg ttttggtcaa aacagccgta
    23941 aaattgatga caatgcttct tatatgcaag aaattatttc agaagatatt caaaagtttg
    24001 ggcttattcc agaatttatt ggtcgtttac cagttgtggc agcccttgaa caactaaaca
    24061 catcagattt gattcaaatt ttgacagaac caagaaatgc cctggtcaag caatatcagg
    24121 ctcttctttc ttacgatggc gtcgaattgg catttgataa ggaagcctta gaagccattg
    24181 ccaataaagc cattgaacgt aagacaggag cacgtggtct tcgttctatt atcgaagaaa
    24241 cgatgttaga catcatgttt gaaattccaa gccaagaaga tgtcacaaaa gtgcgtatca
    24301 ccaaggctgc tgtcgaaggc aagtcaaaac ccgttttaga gacagcttaa ggagaaataa
    24361 tggctgaaga acaagtctta aatacccata acgcatcaat tttattgagc gctgccaata
    24421 aatctcatta cccccaagat gatttgccag aaattgccct cgctggacgt tcaaatgttg
    24481 gtaaatcaag ttttattaat accatattgg ggcgcaaaaa tttggcaaga acctcaagca
    24541 agccaggaaa aacccaacta ttaaattttt tcaatattga tgacaagctt agatttgtgg
    24601 atgtccctgg ttatggctat gccaaggttt ctaaaagtga acgggccaaa tggggaaaga
    24661 tgatcgaaga atacttaacc agcagagaca atctgcgtgc agtcgtgagt ttggtggatt
    24721 tacgtcatgc cccttcaaaa gaagatattc agatgtatga ctttttgaag tactatgaca
    24781 ttcctgttat tgttgtggca accaaagcag ataagattcc tcgtggcaaa tggaacaaac
    24841 atgagtctgt ggtcaagaaa gctttgaatt ttgacaaatc tgatactttt atagtatttt
    24901 cttcggtaga acgtattggt atcgatgatt cttgggatgc tattttagag caggtctagc
    24961 gataggtgtt gatttatcta tgctaaaaca ttctcagtag agggtgtttt tcttatcgaa
    25021 aacataaaaa atcatagtta ggtttaccga ttttacttga cgccttaatg atgacatgct
    25081 agtattttat attaaggaga tgagtcatga cacaagtagc ccaagggcgc tctaaaggaa
    25141 agtcattgtt atgccatcaa tgcaatgccc tttttgtatt tattattttt cttatcttgc
    25201 ttgctgtact ttttggtgtt cgatatcgta atagctctat tgaaggtatc tggcgaacaa
    25261 caagcattga tcagaagtta ggcgatgatt ttgctaaacg tcttactggt ttgcatcaga
    25321 gccctcttat tgatgatagt ttattaacgt catctcagat gatactaaca gttaaaaata
    25381 acaacgttga cttgagtttt agtgttcaag ttgaacgaga catttttgtc aaacgtttag
    25441 ctgcttatca ccaaaatgaa ttattaaaga cattaaagga aaatcattta gttgttggtg
    25501 acttgagtag taaagaacgc caaattattg agaatagtat gccagctagc catgaattag
    25561 aaatgatttt agatcaagct tttgagaaat tagcttctca gatcggaggc aaatataatc
    25621 aaaaaacagg acatttatct gctgttgttc tcaaaggaaa agttaatcgt attttgcaca
    25681 ccattgatat caaagaagaa gtagcagcgg gacatacttc tttttcaaaa ggattgctca
    25741 cacctaatgg ttattttgat tacaccagat ttggaaagaa acttgagtta ttaggcgatg
    25801 aaaaaattat ttttaaaaaa gcgctaaaaa aaaagtccgt caagtgtata acgtagtcac
    25861 aagacggatt ttttcatgtt ttgaaaatta ttcaattgaa gaagtttatt actgatcgtt
    25921 ttgcctaatc actagttgtc cttcttttag gattgcctga agttttttga cttctggatg
    25981 gtcaagataa taatcagtta tacggtcacg aatttcctgt tcgataatac gtcgtaatgg
    26041 acgagctccc atagcgtgat tgtaccctaa atctatcaaa tgagctttag cgtcatcagc
    26101 aatcgttaaa ctaatacctt tttttgcggt ggtttgattt acttcagcta gcattaaatc
    26161 aacaatttct tctaaatttt ctttttgcag atgattaaat ttaatgatac tattaaaacg
    26221 gttcaaaaac tctggtctga aataaggtgc aatgcgatcc ataatgttag actcagaagt
    26281 ttccgtatct tgttggctaa aaccggcatt tgatgtagca ataatgacgg tatttttaaa
    26341 gttaatagta tttccttgtc catctgtcaa tcgtccatca tctaacactt gtagaagaag
    26401 tgtaatgatt tgaggatcag ctttttcaat ttcatctagt aagacaatag cataagggtt
    26461 acgacgaaca cgctcagtta gggtattatt attatcatcg tagccaacat aaccagccgt
    26521 tgtcccaatc aattttgaca cagcagtgcg atcgttatat tcggacatat caagtcgaat
    26581 aatagcatct ttggaaccaa ataaatcaag tgctaattgt ttagctaact ctgttttacc
    26641 aacaccagtt ggacccacaa aaaggaaaga acctattgga cggttaccat catcaaaacc
    26701 tgctcgattt cgtcgaatag cacgtgctac tgctgcaaca gcctcatctt gtccgatgac
    26761 atggcttttt aagcggctgc taattccttt gagcctttct aaatcattag tccccatgtt
    26821 agagacagga ataccagtta agcgctctac agactctgcg atatcattga ctgtagcagt
    26881 gacattttgg ctttggttat gttgctcaat ttgcttttgt aatgtttcaa tccgtgtttt
    26941 tgctgctaaa gctttttcaa agtcttcttt ggcgacagct ttttcttgac tctctttttg
    27001 tttagctatt tcagtttcga gtgtttttaa gtcagtgacc gggtgttgcg cagctaaatg
    27061 agcagctgtc atatccagta agtcaattgc tttatctggc aggctacgct gtgggatgta
    27121 ttgaatagaa taatcaacag cagcttttag aacattatca ggaagggtaa tatggtggtg
    27181 ttgttcataa agattacgaa tacacattaa aatgtgaaaa gtatcttcag ctgatggtgc
    27241 attcacttta acttcattaa agcgacgagc aagagcagca ttttttaaaa tagtattgcg
    27301 gtattcgtct tgagtagtag caccaatcag tgttaattct cctcgtgaca aggctggttt
    27361 aagaatatct gcaagtccct ttgagcctga atcactgctt gtggcaccag caccaactat
    27421 ttgatgaatt tcatcaaaaa ataagatgat attcccagct tcttttactt cttgaatcaa
    27481 gttttgaatg gtctcttcaa aggaaccacg atactgtgta ccagcttcaa gactagaaat
    27541 atcaattgat acgatttcct tgtttttaat agcagctggg acatctccat taacaatggc
    27601 ttgagctaaa ccttcaatga ctgcagtttt accgacacca gcatctccga caaggacagg
    27661 attattttta gttcgtcgtg ccaagatttc agcggtatct tgaatttctt tgttacgacc
    27721 aatgacgggg tcaaggtgcc cttgacgagc ttcttgtgtt aagttagttc cgagttgagt
    27781 caatacacta tcagctttag gtgttaacat ttgagaattt gttgctttgg ttgtcgctac
    27841 agggagttgt cctgtttgac gatagtgttg gaattcttcg ggagttattt cgcgaccgtt
    27901 aacgagatag cggggatttt cgctacgata accacccatg tttgccatta attgattgaa
    27961 aatatcatcc atatttacaa aaggatcttt accagaaaaa tgtgtcatat cagttacctc
    28021 gcaataaaaa atagactata agatgtttgt aagcagtcgc agaatcgttg ttaggatttc
    28081 acatgatagg aaaccctttg ctaataaaat gattcagaca ttatttttac tcatcttata
    28141 gtattattat aatcaaaagg tcagtaaagg tcaaacaaaa acacttgatt ttcaaaaagc
    28201 taaataaaca cgaaaagtaa gtgcttatat gatgacttta gaataaatca taagttttaa
    28261 aaagatcatc ctattctata gcacttaggc tgtcaatgag agaaaaacaa atgttttcat
    28321 taacaagttg gcgctttcat ggtataataa agtgctaaga cgcaattcta ttataagggg
    28381 gaatcatgga agcactcaaa aaaattgccg gtgttaccgc tgcgcaatat gtgactgatg
    28441 gcatgaccat tgggcttgga actgggtcaa cggcttacta ttttgttgag gaaattggcc
    28501 gtcgcgtaaa gcaagaagga ctgcaagtgg ttggtgtgac cacgtcaagt gtgactagca
    28561 agcaagcaga aggcttaggc attcctttaa aatcgataga tgatattgat agcattgacc
    28621 tcaccgtaga tggtgctgat gaagtggata aggatttcaa tggaatcaag ggtggcggcg
    28681 cagccttact aatggaaaaa attgttgcaa caccaacaaa agaatacatc tgggttgttg
    28741 atgcttctaa aatggtagag catctgggtg cctttaagtt accagtcgaa gtcgttcaat
    28801 atggtgctga tcgtttgttc cgtgtctttg aaaaagctgg ttacaaaccg tcttttcgta
    28861 tgaaaggtga tagtcgtttg gtgacagaca tgcaaaacta tattattgat cttgatttgg
    28921 gttgtattaa agatcctgtt gcttttggtc acctgctaga tggaacagtt ggtgttgtgg
    28981 aacacggtct ctttaatggt atggttgata aggtgattgt tgctagtaaa gacggcgtta
    29041 ctgttttaga agcgcctaaa gcaggctagt cttagcatat aacagtgtta atatatttta
    29101 taggtattgg ggagtcaacc gtaacctccc ctagattgga gacttatgtc aaaatttaat
    29161 cgtattcact tggttgtttt agactctgtc ggtgttggtg cagcgccaga tgctgacaaa
    29221 ttctttaatg ctggtgtagc tgatacagat tctgacaccc tcggtcatat ttcagaaaca
    29281 gcaggcttat cggttccaaa tatggcaaaa attggacttg gaaacatttc tcgtccgata
    29341 ccactaaaaa ctattccaac agaagacaat cctactggtt acgtgaccaa attggaagaa
    29401 gtatctcttg gaaaagatac catgacaggc cattgggaaa ttatgggctt gaacattacg
    29461 gaaccttttg acactttctg gaatggtttc ccagaagaga ttttaactaa gattgaagaa
    29521 ttctcaggtc gcaaaattat tcgtgaagct aataaaccct attcaggaac tgcggttatt
    29581 gatgattttg gtccgcgtca aatggaaaca ggtgagttga ttgtttacac ctcagcagac
    29641 ccagtgcttc aaattgcagc ccatgaagac attattcctg tggaagagct ttacaagatt
    29701 tgtgaatatg ctcgctccat cacgcttgaa cgccctgccc ttttaggccg tattattgcg
    29761 cgtccttatg taggcgaacc aggaaacttt acacgtacgg ctaaccgtca tgactatgca
    29821 gtgtctcctt tccaagatac cgttttgaac aaactggctg acgcaggcgt cccaacttat
    29881 gccgttggta agattaatga catctttaat ggttcaggta ttacaaacga catgggacac
    29941 aataagtcga acagccatgg tattgacacg cttattaaga ctcttcaatt acctgagttt
    30001 actaagggat tctcctttac taacctcgtt gattttgatg ccaactttgg tcatcgtcgt
    30061 gacccagagg gttatcgtga ctgcttgcat gaatttgaca atcgcctacc tgaaatcttc
    30121 gcaaatatga aagaagacga tttgcttctc atcactgctg accatggtaa tgacccaacc
    30181 tatgcaggca ccgaccacac tcgtgaatac attccattgc ttgcctactc tgcatccttt
    30241 actggaaatg gtcttattcc acaagggcat tttgcggata tttcagcaac tgttgcagaa
    30301 aattttggag ttgatacagc catgattggg gagtcattcc ttggtcactt aaaataagaa
    30361 aattagttga taatggaaga aatcacgatt tatcataatc caaactgtgg tacttcacgt
    30421 aatgttcttg ccatgattcg ccatgcaggt attgagccta ctattattga gtatttgcag
    30481 acgccaccta atcgggagac tttaattgag ctcttacaat cgatggcaat ctctgcgcga
    30541 gaactcttgc gaaccaatgt tcctgaattt gaggctcatg gattagcaaa tcaagcagta
    30601 gctaagaaag acgttattaa tgccatgttg acggatccaa ttttgatcaa tcgtcctatt
    30661 gttgtgactc gcaaaggagt aaaactttgc cgtccttctg agaccttact ggatattctt
    30721 cctgttcccc tgcctagtcc ttatatgaaa gaggatggcg agagtgtgaa ccctattgag
    30781 gtaaaaggag aaaaagatgt cattgatgac taaaattaac gaaacaaaag actttttagt
    30841 tactaaagga attgaaactc ccgaatttgg attaattctg ggttcaggcc ttggtgaact
    30901 tgctgaagaa gtagaaaatg ctattgttat tgattatgca gatattccaa actggggcaa
    30961 gtcaacggtt gttggccatg ctggaaagtt agtttacgga gatttagctg gccgtaaagt
    31021 gctcgcctta caaggacgtt tccattttta cgaaggaaat ccgcttgaag tggtgacttt
    31081 ccctgttcgt gtcatgaaag ctcttggatg tgaaggcgtt cttgtcacaa atgcagctgg
    31141 tggtatcggc tacggcccag gtaccttgat ggcaatcaca gaccatatca atatgaccgg
    31201 aaataaccca ctaattggtg aaaacttgga cgagtttggt ccacgcttcc ctgatatgtc
    31261 tgatgcctat actaaggttt atcgcgataa ggcatatgaa gtggctgaaa aaatgaacat
    31321 caaactagaa gatggtgttt atatgggctt gactggtcca acttatgaaa caccagcaga
    31381 aatccgtgct ttcaaagtat taggagcaga tgctgttggc atgtcaactg taccagaagt
    31441 tattgtggct gctcattctg gacttaaagt gcttggcatt tcagctatta caaactttgc
    31501 agctggtttt caatcagaat tgaaccatga agaagttgtg gaagtgaccc aacatatcaa
    31561 agaagatttc aaaggtcttg ttaaagctat tttagcggag ttgtaggacg aacaaaatca
    31621 actggagcat tattacagga atgttatttt atgtcgtcag tttggcacat ctgttcgcaa
    31681 taaaaaaatc aaaaaataat cacggagtgt gagttccatg aatgttgaac tcagattcta
    31741 gcttttctaa ctaacataac caacgaaggg aaagagacgt attcggttta aattaagcat
    31801 ggactcgaac atttcttcgt attaattttt aaataataaa ggaaagagag ttagtccttt
    31861 cttatttgaa ctcgattttt agctctcttc ttctattcaa tatcaattat gaaaggaatg
    31921 gggttgtatt caattgaata cgggcggaga actgtttttc ttccttataa aaaataaaaa
    31981 aataagaaag gtgagggctg agttcattaa tttgaattcg ggctaaggac ttggtcaaaa
    32041 agataagttg tctagaaaat caggattttc tgccaacttc ctattttgcc atcgttcttt
    32101 taacgccctc agtatcataa tttatgtcta tccatatttc tgccaaaaaa ggcgatattg
    32161 ctgataaaat tcttctacct ggagatcctt tgcgcgcgaa atttatcgct gaaaatttcc
    32221 tagaagatgc agtgtgtttt aacgaagtgc gtaacatgtt tggctacaca ggaacttaca
    32281 aagggcaccg cgtttctgtc atgggaactg gtatggggat gccttcgatc tctatctatg
    32341 ctcgtgaatt aatcgttgat tacggtgtca aaacattgat ccgtgttggt actgcgggtg
    32401 cgattgaccc agaagttcat gtgcgtgaat tggtgcttgc ccaagcagca gcaaccaact
    32461 caaacattat ccgtaatgac ttcccagaat ttgatttccc acaaattgct gattttggtt
    32521 tacttgacaa ggcttaccat atcgccagag aaatgggagt aacaactcac gttgggaatg
    32581 tgctttcttc tgatgtcttt tacactaaca tgcctgagcg taatatggct cttggtaaat
    32641 tgggtgttaa agccatcgaa atggaagcag cagctcttta ctatttagct gctcagcacc
    32701 atgtcaaagc ccttggaatc atgacgatct cagataactt gaatgatcca accgaagata
    32761 ctacagctga agagcgccaa accactttca ctgatatgat gaaggtcggc ttggaaacct
    32821 taattgccaa tgactaataa tcaaacacta gacatccttt tggatgtcta tgcttataat
    32881 cacgccttta gaattgctaa agccttgcca aatatcccta aaactgccct ctatttacta
    32941 gagatgttaa aagagcgcag agaattgaac cttgcctttc tggcggaaca tgcagcagag
    33001 aatcggacca ttgaagacca gtaccactgt tcattatggc ttaaccaatc gcttgaagat
    33061 gagcagattg ccaattacat tttggattta gaagttaaag taaaaaacgg tgctattatt
    33121 gatttcgtca ggtcagtgtc gcctattctt taccgacttt ttctcagact aatcacgtca
    33181 gaaattccaa acttcaaggc ttatattttt gatacaaaga atgaccaata tgatacctgg
    33241 cattttcagg ccatgttgga atctgatcac gaggttttca aggcttacct gtctcaaaag
    33301 cagtctcgca atgtgacgac caaaagctta gcagacatgt tgacgttgac ctccttacct
    33361 caggaaatca aggacttggt ttttttgtta cgacattttg aaaaggctgt ccgtaatcct
    33421 ctggctcatt tgattaagcc ttttgatgaa gaggaactgc atcgcaccac tcatttttct
    33481 tctcaggctt ttttggaaaa cattatcacc ttggcgactt tttctggtgt aatctaccga
    33541 cgtgagcctt tttactttga tgacatgaat gccattatta aaaaggagtt gagcctttgg
    33601 agacaatcta ttgtctgata tttatcaaaa aacacgataa cttgaccgat acaggtctta
    33661 ctaccgtgtt tttttagtat gacgattgaa aaagacatta atcaaaggtt acttcttcga
    33721 gaaggtattc gataaaacgt tcccccattt tggacaagtt ggctttttca tgcttgataa
    33781 aaacaatgtc aatttcgtca gggacatcta gcgggatagc cacaatctgg tcaccattta
    33841 gattgctatt tagaatacca ctggcaacgg tgtagccatc taaaccaatc attaagttaa
    33901 agagggtggc acggtcactg accacaattg atttgttgtg gggcatctgg gacatcatct
    33961 cttctgaaaa ataaaaggag ttgtgaatcc cttggtcata gctcaggtaa ggaaaatctc
    34021 tcaagtcgtc catgcttaat aggcttttag ttgctagagg atttgatttg ctgacaaaaa
    34081 tatgaggctg tgccttaaat aatggagagg cagtcaaatg attgtcatca aataatttgg
    34141 tcaagacatc tcggttatag tcgttgataa agagaacacc aatttcagat cgaaagtttt
    34201 tgacatcatc aatgatttcc caagttcttg tctcgcgcaa aaagagttcg taccgagtca
    34261 tgtcggtccg cttgaggagt gagacaaatg cattgactac gaaggcataa tgttgagatg
    34321 aaacgctaaa gagctctcgg ccagtattgt ggtttttata gcggtcttct aacagtgatg
    34381 tttgctctat aatttggcga gcataagata aaaattccac cccatctttt gtcaaggtga
    34441 tccctttagg atttcggttg aaaatggtaa tgcccatctc catttccaaa tccttgaccg
    34501 cattggatag acttggttgt gtgataaata attgcttagc agcttcattc atagagccgc
    34561 actcaacaat tttgataata taatgcagtt gttgaattct cataagtaca gtctagctca
    34621 aaaaaaataa agacgcaagc acaaacgtca tcatgggttt agaactttga aaaagcgctg
    34681 gagtcttttc tcaatatggc ctaggataaa tatgattcaa ttttgagagt tgaatctatc
    34741 aatttcattg cccttttatt tttcttgtgt tatattaata gtattaacaa ataggtattt
    34801 ttctaatcaa agggtggtgg tcgtgtgaat gttactgaac aaaatagtca tcaaatctta
    34861 atccaaaaat tattggtcag tatccactat ttgactcttt ttcgagatga actgaagctt
    34921 gtagaacgaa ctccttctat acttggaggg gaatttccag ctcatttagt acagtctgag
    34981 ttgggagata ttgttgcggc cattgatacc ttggatatgc agcaacgctt gattgagtct
    35041 accttttggt atgaagaatc agcttttaag ttgatgaaca aaactttgga tattgtcgat
    35101 aattggatta aaggagtgga tcatctgata gatttatgcc agtccaaaga agtctttcaa
    35161 attattattg gagataaacg cattcgagtt tttggggtct taagtgatgt tttttcatct
    35221 ttaaaagtga gtgctttgtc acttaaggaa gctcctattc cggatttgct ctatgaacat
    35281 atccagaggg ttaatcttga agaagaagct tttataaaat attaccaagg ccctaaggta
    35341 cccacaggtg agtttgaata aatgattggg taaaaatgat aaaatgagtt gacgtaagta
    35401 tacaaaaaaa gatatagtag gaaaaatgtg ttcaaataac aaaaagtttt gacaccttgt
    35461 tttaaaaaag ctataatagt ttaaatttag acacctttaa gtgagtccag agaggcaaac
    35521 aaggtataca agataaaaaa agggaattcc cttttagttt gctgtagcct cgcttctttg
    35581 gtagcgaggc tttttggtgc ttaatgagat attgacacat tatagaaagg ataagttatg
    35641 aaagaagaac gcccaattat tgctttagac ttttcatcat ttgaggagac taaagcattt
    35701 ttagacttat ttccagcaga agaaaaacta tacgtgaaaa ttggtatgga attatattat
    35761 gcgcaaggac cagatattgt tcggtatatc aaatcgttag ggcataatgt atttttggat
    35821 ttaaaattac atgatattcc aaatactgtt cgtgctgcta tggcagttct taaagaatta
    35881 gatattgata tggcaactgt tcatgcagct ggtggtgtag agatgctaaa agcagctcga
    35941 gaaggactag gtcaaggccc taccttaatt gcggtaacgc agctaacttc aaccagtgaa
    36001 gaccaaatgc gtggtgatca aaatattcaa acgagtcttt tagagtctgt tttgcattac
    36061 agcaaggggg cagctaaagc tcagctagat ggggtggttt gttcggcaca agaagtagaa
    36121 gctatcaagg cggtgacgcc tacgggattt acttgcttaa ctcctggcat tcgtcctaaa
    36181 ggcagtaata ttggcgatca aaaacgagtg atgactccaa accaagcaag acgcattgga
    36241 agtgattata ttgtggtagg gcgaccaatt acccaggcaa aagacccagt ggctgcttac
    36301 caagctataa aagctgagtg ggcaggctaa cagataagat taggaaacca acacttgtct
    36361 gttaaagaag aaaaaggaga ataagaaatg acactagcaa gccaaattgc aactcaatta
    36421 cttgatatta aagctgttta tttaaagcct gaagatcctt ttacgtgggc atctggcatt
    36481 aaatcaccta tttacactga taatcgtgtc accctttctt atcctaagac tcgtgattta
    36541 attgagaatg ggtttgtgga aactatcagg gctcatttcc cagaagttga ggtcatcgct
    36601 ggtacagcta cagcaggtat tcctcatggt gccattatag cagataaaat gactcttcct
    36661 tttgcttata ttcgcagtaa gccaaaagat catggagcag gcaaccagat tgaggggcgt
    36721 gtgcttaaag gccaaaaaat ggttatcatt gaagatttga tttcaacagg tggttcggta
    36781 ctagatgcag ccgcagcagc cagtcgtgag ggagctgacg ttctgggagt tgttgcgatt
    36841 ttcacttatg agttaccaaa agctagtcag aattttaaag aagctggtat caagttgatt
    36901 acgctttcta attatactga gctaattgca gttgcaaagt tgcaaggcta tattactaat
    36961 gatggtttac atttacttaa aaaatttaaa gaagaccagg taaactggca acaataagga
    37021 actatcagcc aggtttattt ttaatgaaaa aatctcttta accccaattc aaaatgttat
    37081 gttttgattg ttttgtctac attccttaca catcacattc taatttctaa ccttttaatg
    37141 gtggttttct tttatttgtg ttttaataaa aaagaatgtt ttaggattca tatcttagaa
    37201 aggaagagta gctatgactt atcaagatgc gacggctatg gctattgctg ttcagactgg
    37261 tcagaccaca ccactagaat tagtaaccca ggctatttat aaggctaaaa agttgaaccc
    37321 taccttaaat gctattacct cagaacgctt tgaagcagcc ctagaagaag ccaaacaaag
    37381 ggatttttca ggtctgcctt ttgctggtgt gcctcttttt ttaaaagatt tgggacaaga
    37441 attaaaaggt cactcatcaa cctcaggttc cagattgttt aaagagtacc aagcaactaa
    37501 aacggattta tttgtgaaaa gattagaagc tttaggcttt attattttag ggcgctccaa
    37561 cacgcctgaa tttggcttta aaaatattag cgatagcagt ttgcacggac cagtgaattt
    37621 accaaaggat aatacacgaa atgctggtgg ctcatctggg ggagctgctg ctctagtgtc
    37681 atcaggaatt agtgcactag caactgctag tgatggtggt ggttctattc gaattccagc
    37741 ctcgtttaat ggcttaattg ggctcaaacc tagccgtggg cgcatgcctg tcggacctgg
    37801 ttcttatcga agctggcaag gagcctcagt tcattttgcc ttgaccaaat ccgttagaga
    37861 tactagaaat ctactctact atttacagat ggaacaaatg gaaagcccct tccccctagc
    37921 caccttaaca aaagatagta tttatcaatc gctacaacgt cccttgacaa ttgcttttta
    37981 tcaacggtta agtgacggta gcccagtatc tttagatact gcaaaagctt taagacaagc
    38041 agtaacttgg ctaagagaac aagggcatca gctagttgaa ttggaagagt ttcctgtaaa
    38101 tatgacagaa gtgattcgtc attattatat tatgaatagt gtggaaacgg ctgctatgtt
    38161 tgctgatatt gaagacactt ttggacgtcc gatgaccaaa gacgatatgg aaaccatgac
    38221 ctgggctatt taccaatcag gtaaagacat cccagcttgg cgttactcac aggtccttca
    38281 aaaatgggat acgtacagtg caaccatggc tagttttcat gagacttatg acctgttgtt
    38341 gacgttcaca accaacacac cagctcctaa gcacggagaa cttgtcccag attcgaaact
    38401 catggctaac ttggctcaag ctgaaatttt cagcagtgaa gagcaattca atttggtcga
    38461 aaccatgttt ggtaagagtc tggctattaa tccttacaca gctctgccta atctaactgg
    38521 ccagccagct attagtttac ctacttacga aactaaggaa gggctcccaa tgggcattca
    38581 actaattgca gccaaaggta gagaggacct attattagga attgcagagc agtttgaggc
    38641 agcaggatta ttgaagattc ctcaataata atcttataaa acagtttaac tattatagat
    38701 taacttttta aagagattga gcgctcactg ataacacaac ttaatcaaaa tgttatacta
    38761 ttcttatctt aataaaggag ttactatgaa gaaatcagtt actttactgt ctatcggact
    38821 tgccagcctt ttattggcag catgtgcgcc acataaatct caaaaatcaa gttgggacac
    38881 tatcaaagaa aaaggggtgt taaaagtagc taccccagga acctatcagc caacttcttt
    38941 ttacaacgat aataatgagt tagtaggtta cgaagtagat atggtcaaag aaatcggtaa
    39001 acgacttaac attaaagtca agtttgttga aacaggattt gaccaagcct ttacctcagt
    39061 tgatagtggt cgagtggata tttctttgaa caactttgac attaccccaa aacgtcagaa
    39121 aaaatacaac atctctacgc cttataaata cggggtagga ggcatgattg tccgtgctga
    39181 tggcagctca aacatggtta aaaaagatct tagcgactgg aaaggaaaaa aagcagctgg
    39241 tgcttctgga acagaataca tgaaagtagc gcaaaaacag ggagctgaac tggtgaccta
    39301 cgataatgtt acaggagatg tttatctaaa cgatgtggct aacggtcgaa cagatttcat
    39361 tccaaatgat tacccagctc aaaaattatt tgtggattac atgttatctc aaaatccaaa
    39421 tctaaatgtc aaaatgagcg atgttcagta caacccaacc gaacaaggaa ttgttatgaa
    39481 caaaaaagac gatagcctca agaaaaaaat agatgctgtt attaaagaca tgataaaaga
    39541 tggtagcttg aagaaaatct ctgaaaccta ctatgctggt caagatctga caaaaccttt
    39601 tggcaaagac aaaaaaattc ccgtcattga tacgaaagac gttaactaat acttgatgtt
    39661 aaaggagtcc taaccacatg attaatatcc cattaatgaa agatagttta ggatttgtgt
    39721 tatcgggatt accttatacc cttggtattt cgttgctcag tttttttacg ggtctgtttt
    39781 taggtttagg cctagccctt ctgggaaggt cacgtcagcc gttgattcat tatcttgtta
    39841 gagcgtacat ctctattatg cgaggtgtgc cgatgatcgt ggtgctcttt gttctttatt
    39901 tcgggttgcc ttattatggt ttagaattgc cagctttact ttgcgcttat cttggttttt
    39961 ctatggttag cgctgcctat atttctgaag tttttcgctc ttctatagaa gctattgaca
    40021 agggacagtg ggaagcagct aaggctttag ggttgccata tgctcttatg gttaagaaaa
    40081 ttattcttcc tcaagctttt cgaattgcag ttcctcctct aggcaatgtc attattgata
    40141 tggttaaaag ttcgtcgcta gctgccatga ttaccgtacc agatattttt caaaatgcca
    40201 aaattattgg cggtagagag tgggattaca tgtccatgta tattttagta gcctttatct
    40261 attggcttat tgcttttttg ttagaacgtt accaagaatt cttagaaaat aagctagcac
    40321 ttgtttaata tcctgtaaaa aacgaatatt aaccctggaa atatcatatt ttcagggtct
    40381 ttctatttaa aatgtggtaa actagataga aaaggacatc gtatttaact tagaaactga
    40441 cgtgattaga aaggaatctt atggctcatt caatttggca tgagaaaatc aaatcatttt
    40501 tgccggagca ttactacggt cgcatcaatc actttttaga tgaagcctat gcttccggtc
    40561 ttgtctatcc tccacgagaa aatgtcttta aagccttaca agtcactcct ttggaagaaa
    40621 ccaaagtgtt gattttagga caagaccctt atcatggccc caaacaggcc cagggcttat
    40681 cattttcagt tccagaagag atttctgctc cgccatccct tattaatatt ctaaaagaat
    40741 tagcagatga cattggtcct cgtgaccatc atgatttaag cacttgggct agtcaagggg
    40801 ttctgctttt gaatgcttgc ttaacagtgc cagcaggcca ggctaatggg catgcaggct
    40861 taatatggga gccatttaca gacgctgtta ttaaagtact gaatgagaaa gacagccctg
    40921 tagttttcat tttatgggga gcttatgcaa ggaagaaaaa agccttcatt actaatccaa
    40981 agcaccacat catcgagagc cctcatccaa gccctttgtc atcttatcgt ggcttttttg
    41041 gcagcaaacc cttttcaaga accaacgcta ttttagaaaa agagggcatg actggcgtag
    41101 attggctaaa ataagccagc catttcaact aaatagctta agctagacat tttgatacct
    41161 ttaataagtg aaatga
//
