LOCUS       NZ_SWMS01000041        23292 bp    DNA     linear   CON 10-DEC-2024
DEFINITION  Prauserella endophytica strain CGMCC 4.7182 Scaffold41, whole genome
            shotgun sequence.
ACCESSION   NZ_SWMS01000041
VERSION     NZ_SWMS01000041.1
KEYWORDS    WGS; RefSeq.
SOURCE      Prauserella endophytica
  ORGANISM  Prauserella endophytica
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Prauserella; Prauserella
            coralliicola group.
REFERENCE   1  (bases 1 to 37655)
  AUTHORS   Liu,J.M., Habden,X., Guo,L., Tuo,L., Jiang,Z.K., Liu,S.W., Liu,X.F.,
            Chen,L., Li,R.F., Zhang,Y.Q. and Sun,C.H.
  TITLE     Prauserella endophytica sp. nov., an endophytic actinobacterium
            isolated from Tamarix taklamakanensis
  JOURNAL   Antonie Van Leeuwenhoek 107 (6), 1401-1409 (2015)
   PUBMED   25832628
REFERENCE   2  (bases 1 to 37655)
  AUTHORS   Li,Q.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-APR-2019) Yunnan Institute of Microbiology, Yunnan
            University, No. 2 Cuihu North Rd, Kunming, Yunnan 650091, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 10.16x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_005146945.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 16:32:08
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,852
            CDSs (total)                      :: 7,795
            Genes (coding)                    :: 7,703
            CDSs (with protein)               :: 7,703
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 34 of 92
            Pseudo Genes (incomplete)         :: 69 of 92
            Pseudo Genes (internal stop)      :: 2 of 92
            Pseudo Genes (multiple problems)  :: 13 of 92
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 18:09:25
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 23292
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            SWMS01000041.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23292
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NAPAA"
                     /region_number="1"
                     /rules="(AMP-binding and TIGR02353)"
                     /tool="antismash"
     cand_cluster    1..23292
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(AMP-binding and TIGR02353)"
                     /kind="single"
                     /product="NAPAA"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23292
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[4428:8292](-)"
                     /cutoff="5000"
                     /detection_rule="(AMP-binding and TIGR02353)"
                     /neighbourhood="15000"
                     /product="NAPAA"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(4429..8292)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(AMP-binding and TIGR02353)"
                     /neighbourhood="15000"
                     /product="NAPAA"
                     /protocluster_number="1"
     gene            complement(65..979)
                     /locus_tag="FCN18_RS36035"
                     /old_locus_tag="FCN18_36030"
     CDS             complement(65..979)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007023969.1"
                     /locus_tag="FCN18_RS36035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_36030"
                     /product="proteasome assembly chaperone family protein"
                     /protein_id="WP_112274729.1"
                     /transl_table=11
                     /translation="MVSDPGELYEVDSDVPVLDSAVLLYHFDGFIDAGAAGRAVADHLL
                     EELDGPVVARFDVDRLIDYRSRRPTMTFSGDHWSDYEAPELAVRLLHDENATPFLVFTG
                     PEPDHEWERFAAAVRHLVERWQVRLSVGFQGIPMGVPHTRPLGLTAHATRAQLVDEYQP
                     FFNEVRIPGSAAAMLELRLGQAGHDAIGFAAHVPHYLAQARYPAAALTLLDAITRATGL
                     SLPSDALREAARSTDEEVDRQVRESDEVAEVVSALERQYDAFTAASAKGNLLADNTPMP
                     TGDELASQFERFLAEQGGNDNEQ"
     gene            1097..2410
                     /locus_tag="FCN18_RS36040"
                     /old_locus_tag="FCN18_36035"
     CDS             1097..2410
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020672075.1"
                     /locus_tag="FCN18_RS36040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_36035"
                     /product="ROK family protein"
                     /protein_id="WP_228714308.1"
                     /transl_table=11
                     /translation="MQEPKTPRTPTVPSPEHVDSLATVLDLVRSGVARTRPEIGRHSGL
                     GRTVVTQRVNQLTECGLLEEGALGPSSGGRAPRELRFRARAGLVLAAELGATSVGVGVT
                     DLSGTVLAEREEAADIALGPDPVLERVEILFDELLAEIRAEHGDVAVWGIGIGLPGPVE
                     FATGRPSAPPIMPGWDGYPVRDRLTARFGAPVWVDNEVNTMALGELRAGSAKGQRDILY
                     VKIGTGIGAGLVSGGRLHRGSQGCAGDIGHAAVADEATVVCRCGNTGCLEAYAGGAALA
                     RDGLAAAQEGRSEFLAGVLESTGTVTAADVSRAAQSGDRTSVELLTRAGRLIGSLLATL
                     VSFYNPALVIIGGGVAAAGDLLLAAVRESVYRRSLPLATRELRIARSTLSDRAGLVGAA
                     FMVIDELFAPERLAHWVAAGSPAGAPELVNVPLRAPLL"
     gene            2420..3040
                     /locus_tag="FCN18_RS36045"
                     /old_locus_tag="FCN18_36040"
     CDS             2420..3040
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020672072.1"
                     /locus_tag="FCN18_RS36045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_36040"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_137097285.1"
                     /transl_table=11
                     /translation="MPDRVYGGRTAADRRAERRQRLLDAGLELFGTEGYVATSIERLCS
                     AAGVSTRNFYEEFTGREALLTALHDMVLERALKAVADAFARAENEPLALRIELAVRAYI
                     ATTAEDHRWARLSYVEIVGVSETVERHRLAWRERWVAFLVAEARRAVEHGEAMSRDFHL
                     SAVALIGAVNELVYHWAVGDHRIPLDDVIAEIVRIATVTLTGP"
     gene            complement(3117..4418)
                     /locus_tag="FCN18_RS36050"
                     /old_locus_tag="FCN18_36045"
     CDS             complement(3117..4418)
                     /EC_number="3.4.11.-"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020640222.1"
                     /locus_tag="FCN18_RS36050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_36045"
                     /product="M1 family metallopeptidase"
                     /protein_id="WP_112274731.1"
                     /transl_table=11
                     /translation="MRSSAAPGAATSGDAYLPEHGNGGYHVRHYDLELDYRIGANRLSG
                     RGRIEAVATQALSRLSLDLAGLKVGRVFVGGRPARYAHRGHKLAITPALPLAEGEEFTV
                     EVRYSGNPRPLASRHWDEIGWDELSDGVLVAAQPIGAPSWFPCDDHPSGKATYRVALTT
                     ASAYSVYVTGTLVSRQRSASTTTWVYEQHAPTATYLMSVQIGRYTELEPGPAQRLAVPP
                     GLRARAETDFARQPRMLEVLAEHFGPYPFEEYVVVVTDDELDDPVEAQGMAVFGANHVD
                     GRRTHERLVVHELAHQWFGNSLTVAGWRHIWLNEGFATYAEWLWSQASGGQSADEHARY
                     WRGVLAGRPGLRLADPGVARMFDEGVYKKGGLLLHALRGELGDEAFFGLLRAWTDTHRH
                     ATVTTDQFTALAARHAGRPLDAFFAAWLDGTDLP"
     gene            complement(4429..8292)
                     /locus_tag="FCN18_RS36055"
                     /old_locus_tag="FCN18_36050"
     CDS             complement(4429..8292)
                     /GO_function="GO:1904091 - non-ribosomal peptide synthetase
                     activity [Evidence IEA]"
                     /NRPS_PKS="Domain: AMP-binding (37-409). E-value: 2.4e-77.
                     Score: 252.2. Matches aSDomain:
                     nrpspksdomains_FCN18_RS36055_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (511-578). E-value: 3.7e-15. Score:
                     47.9. Matches aSDomain: nrpspksdomains_FCN18_RS36055_PCP.1"
                     /NRPS_PKS="Domain: TIGR02353 (598-1282). E-value: 9.6e-228.
                     Score: 749.7. Matches aSDomain:
                     nrpspksdomains_FCN18_RS36055_TIGR02353.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NAPAA:
                     TIGR02353"
                     /gene_functions="biosynthetic (rule-based-clusters) NAPAA:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020672070.1"
                     /locus_tag="FCN18_RS36055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_36050"
                     /product="Pls/PosA family non-ribosomal peptide synthetase"
                     /protein_id="WP_113644490.1"
                     /sec_met_domain="AMP-binding (E-value: 4.6e-65, bitscore:
                     210.9, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.3e-10, bitscore:
                     33.0, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR02353 (E-value: 5.7e-228, bitscore:
                     749.7, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLAIDAAPTGPATPTAGRALFWSGLAPSERTLLDILAETAARHP
                     GAPALDDGTETLTYRALAEEIETVRGKLAAAGIGRGDRVGVRISSGTAELYVAILAVLS
                     LGAAYVPVDADDPAERAELVFGEAGVCAVLGDGGALTPCGTPGGAPGAPAPGDDAWIIF
                     TSGSTGRPKGVAVSHASAAAFVDAEAELFLADEPLGPGDRVLAGLSVAFDASCEEMWLA
                     WRHGACLVPAPRALVRTGVDLGPWLVERRITVVSTVPTLAALWPADALEEVRLLIFGGE
                     ACPPELAERVAVEGREVWNTYGPTEATVVACAAQLTGEGPVRIGLPLAGWQLAVVDDEG
                     RPVAMGESGELVIGGVGLARYLDPAKDAEKFAPLPALGWQRAYRSGDLVRAEPDGLLFL
                     GRADEQIKLGGRRIELGEVDAALQALPGVAGGAAAIRTTKAGNQVLVGYVVPREDFDHD
                     GAVSRLREQLPAALVPLLAVVGDLPTRTSGKVDRAALPWPLSTVDTKESLSPTESWLAE
                     AWGEILGVSVTDAAADFFRNGGGSLTAAQLVSRIRTRHPTVSVTDVYRHPRLGELAALL
                     DALGDATTSRREVAPTPRRAGLVQTLLLLPLFTLAGLRWTTIAAAVSTVLARWAGLAWA
                     PSVPWWALGVAWLVLFSPAGRIAIAAGGARLLLRGVRPGTHPRGGRVHLRLWAAERLAD
                     ASGANAVAGASWMTHYARALGAKVGRDVDLHSQPPVTGLLKLGRGAAVEPEADLSGYWV
                     DGDVVHIGKIRVGAGARVGARSTLLPGARVGKHAEIAAGSTVLGSVPAGQRWAGSPARR
                     EGKASRQWPSEAPRRSRRWVAVYGVTSVLLGLLPAIAAVPALAVLGGAVAGRAPGSALG
                     AALAAVPVATVAYLAAYALLVLCGVRALGIGLREGYHPVHSRGAWRVWATERLMDSARA
                     GLFPLYASLFTPVWLRLLGARVGRGVEASTVLAVPKMTKIDSGAFLADDTMVATYELGH
                     GWLHVAPARIGKQAFLGNSGMTAPGRSVPKRGLVGVLSSTPPKAKKGSSWLGMPPMPLR
                     RSVEDADTSRTFDPPARLRVARAAVELCRVVPVMCGVALAVLVVAALVALTASLGLVVA
                     ALLSGVVLLAAGALAAVTATVAKWALVGRFRVSERPLWSSFVWRAELADTFVEVLAVPW
                     LVGSLGGTPLLSAWLRSMGARIGRGAWLETYWLPESDLVRIGDGATVNRGCVVQTHLFH
                     DRIMSMDTVVLDEGATLGPHGIVLPGAGIGARTTIGPGSLVTRGDVVPADTRWQGNAIA
                     AWR"
     aSDomain        complement(4447..6498)
                     /aSDomain="TIGR02353"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FCN18_RS36055_TIGR02353.1"
                     /evalue="9.60E-228"
                     /label="FCN18_RS36055_TIGR02353.1"
                     /locus_tag="FCN18_RS36055"
                     /protein_end="1282"
                     /protein_start="598"
                     /score="749.7"
                     /tool="antismash"
                     /translation="VQTLLLLPLFTLAGLRWTTIAAAVSTVLARWAGLAWAPSVPWWAL
                     GVAWLVLFSPAGRIAIAAGGARLLLRGVRPGTHPRGGRVHLRLWAAERLADASGANAVA
                     GASWMTHYARALGAKVGRDVDLHSQPPVTGLLKLGRGAAVEPEADLSGYWVDGDVVHIG
                     KIRVGAGARVGARSTLLPGARVGKHAEIAAGSTVLGSVPAGQRWAGSPARREGKASRQW
                     PSEAPRRSRRWVAVYGVTSVLLGLLPAIAAVPALAVLGGAVAGRAPGSALGAALAAVPV
                     ATVAYLAAYALLVLCGVRALGIGLREGYHPVHSRGAWRVWATERLMDSARAGLFPLYAS
                     LFTPVWLRLLGARVGRGVEASTVLAVPKMTKIDSGAFLADDTMVATYELGHGWLHVAPA
                     RIGKQAFLGNSGMTAPGRSVPKRGLVGVLSSTPPKAKKGSSWLGMPPMPLRRSVEDADT
                     SRTFDPPARLRVARAAVELCRVVPVMCGVALAVLVVAALVALTASLGLVVAALLSGVVL
                     LAAGALAAVTATVAKWALVGRFRVSERPLWSSFVWRAELADTFVEVLAVPWLVGSLGGT
                     PLLSAWLRSMGARIGRGAWLETYWLPESDLVRIGDGATVNRGCVVQTHLFHDRIMSMDT
                     VVLDEGATLGPHGIVLPGAGIGARTTIGPGSLVTRGDVVPADTRWQGNA"
     aSModule        complement(4447..8181)
                     /complete
                     /domains="nrpspksdomains_FCN18_RS36055_AMP-binding.1"
                     /domains="nrpspksdomains_FCN18_RS36055_PCP.1"
                     /domains="nrpspksdomains_FCN18_RS36055_TIGR02353.1"
                     /locus_tags="FCN18_RS36055"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     misc_feature    complement(6289..6291)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     aSDomain        complement(6559..6759)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FCN18_RS36055_PCP.1"
                     /evalue="3.70E-15"
                     /label="FCN18_RS36055_PCP.1"
                     /locus_tag="FCN18_RS36055"
                     /protein_end="578"
                     /protein_start="511"
                     /score="47.9"
                     /tool="antismash"
                     /translation="ESWLAEAWGEILGVSVTDAAADFFRNGGGSLTAAQLVSRIRTRHP
                     TVSVTDVYRHPRLGELAALLDA"
     CDS_motif       complement(7039..7101)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FCN18_RS36055_0005"
                     /evalue="6.20E-09"
                     /label="NRPS-A_a8"
                     /locus_tag="FCN18_RS36055"
                     /protein_end="418"
                     /protein_start="397"
                     /score="28.1"
                     /tool="antismash"
                     /translation="FLGRADEQIKLGGRRIELGEV"
     aSDomain        complement(7066..8181)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FCN18_RS36055_AMP-binding.1"
                     /evalue="2.40E-77"
                     /label="FCN18_RS36055_AMP-binding.1"
                     /locus_tag="FCN18_RS36055"
                     /protein_end="409"
                     /protein_start="37"
                     /score="252.2"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="AETAARHPGAPALDDGTETLTYRALAEEIETVRGKLAAAGIGRGD
                     RVGVRISSGTAELYVAILAVLSLGAAYVPVDADDPAERAELVFGEAGVCAVLGDGGALT
                     PCGTPGGAPGAPAPGDDAWIIFTSGSTGRPKGVAVSHASAAAFVDAEAELFLADEPLGP
                     GDRVLAGLSVAFDASCEEMWLAWRHGACLVPAPRALVRTGVDLGPWLVERRITVVSTVP
                     TLAALWPADALEEVRLLIFGGEACPPELAERVAVEGREVWNTYGPTEATVVACAAQLTG
                     EGPVRIGLPLAGWQLAVVDDEGRPVAMGESGELVIGGVGLARYLDPAKDAEKFAPLPAL
                     GWQRAYRSGDLVRAEPDGLLFLGRADEQIKLG"
     CDS_motif       complement(7180..7260)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FCN18_RS36055_0004"
                     /evalue="1.40E-05"
                     /label="NRPS-A_a6"
                     /locus_tag="FCN18_RS36055"
                     /protein_end="371"
                     /protein_start="344"
                     /score="17.5"
                     /tool="antismash"
                     /translation="MGESGELVIGGVGLARYLDPAKDAEKF"
     CDS_motif       complement(7600..7626)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FCN18_RS36055_0003"
                     /evalue="9.90E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="FCN18_RS36055"
                     /protein_end="231"
                     /protein_start="222"
                     /score="-3.1"
                     /tool="antismash"
                     /translation="WRHGACLVP"
     CDS_motif       complement(7759..7818)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FCN18_RS36055_0002"
                     /evalue="2.20E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="FCN18_RS36055"
                     /protein_end="178"
                     /protein_start="158"
                     /score="29.3"
                     /tool="antismash"
                     /translation="AWIIFTSGSTGRPKGVAVSH"
     CDS_motif       complement(7954..7995)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FCN18_RS36055_0001"
                     /evalue="1.00E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="FCN18_RS36055"
                     /protein_end="113"
                     /protein_start="99"
                     /score="12.6"
                     /tool="antismash"
                     /translation="LAVLSLGAAYVPVD"
     gene            complement(8497..9915)
                     /gene="der"
                     /locus_tag="FCN18_RS36060"
                     /old_locus_tag="FCN18_36055"
     CDS             complement(8497..9915)
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /gene="der"
                     /gene_functions="other (smcogs) SMCOG1227: ribosome
                     biogenesis GTP-binding protein YsxC"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009155046.1"
                     /locus_tag="FCN18_RS36060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_36055"
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="WP_112274733.1"
                     /transl_table=11
                     /translation="MTEADGTWSDEAEFLAADTEGAEGEPDDDAELAQPVLAVVGRPNV
                     GKSTLVNRILGRREAVVQDVPGVTRDRVAYDALWNGRRFTVVDTGGWEPGATGLRGSVA
                     AQAELAMSTSDAVLLVVDAAVGATATDEAVAKVLRRSKRPVLLAANKVDDERLLAETAS
                     LWSLGLGEPHPVSALHGRSSGDLLDAIVNALPEAPRDADRVAGGPRRVALVGKPNVGKS
                     SLLNKLTGEERAVVDSVAGTTVDPVDSLVELDGQLWRFVDTAGLRKRVQTASGMEYYAS
                     LRTRTAIDAAEVVIVLLDASEPVSEQDLRVVTLVAEAGRALVLAFNKWDLVDEDRRHQL
                     DRELDRGLVRVPWAERVNVSALTGRAVRKLAPALRTALASWDQRVPTGQLNGWLSDLVA
                     ATPPPVRGGKQPKVLFATQAGIRPPTLVLFTTGFLEAGYRRFIERKFRERFGFQGSPVR
                     INVRVREKKPRKSR"
     gene            complement(9912..10556)
                     /locus_tag="FCN18_RS36065"
                     /old_locus_tag="FCN18_36060"
     CDS             complement(9912..10556)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1141: acyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009155047.1"
                     /locus_tag="FCN18_RS36065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_36060"
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="WP_137097286.1"
                     /transl_table=11
                     /translation="MTGLPRGATPWLHDVGRVIARYLYRPAYRIRVHGAARVPRTGPVV
                     LVANHSSMIEPQLIFGMLPRRSVFLVKEEMFSGPAGWGLRRIGQVPVKRGVPDREALRT
                     ATEVLRDGGLVGVFPEGTRGAGDVAQAQQGAAWLVRVSGAVVVPVAVRGTLNPTGRRRF
                     RPTVDVLVGEPFTVDVGRGRAALAEGTERIRGTLAALVEELDRQREEKQRQ"
     gene            complement(10553..11278)
                     /gene="cmk"
                     /locus_tag="FCN18_RS36070"
                     /old_locus_tag="FCN18_36065"
     CDS             complement(10553..11278)
                     /EC_number="2.7.4.25"
                     /GO_function="GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /gene="cmk"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007035520.1"
                     /locus_tag="FCN18_RS36070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_36065"
                     /product="(d)CMP kinase"
                     /protein_id="WP_113644491.1"
                     /transl_table=11
                     /translation="MAGALRGVVALDGPSGTGKTTVARKLAAKLGAGYLDTGAMYRVVT
                     LAVLRAGIDPTDAAAVAALTSQVQVGVGTDPDNPRAQLNGEDVGEEIRTERVNVAVSPV
                     SAVPEVRQVLVAGQREIIEAVLGSVGGIVVDGRDIGTVVAPGAPLKVFLTASAEVRAAR
                     RSAQDSAAGRDSTPEHARASVERRDQLDSTRTVSPLRAAEDAVVFDTSELSIEQVITAL
                     SELASRRGLLGGEFAEASR"
     gene            complement(11335..11676)
                     /gene="mnhG"
                     /locus_tag="FCN18_RS36075"
                     /old_locus_tag="FCN18_36070"
     CDS             complement(11335..11676)
                     /GO_function="GO:0015297 - antiporter activity [Evidence
                     IEA]"
                     /GO_function="GO:0051139 - metal cation:proton antiporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0098662 - inorganic cation transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /gene="mnhG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007025529.1"
                     /locus_tag="FCN18_RS36075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_36070"
                     /product="monovalent cation/H(+) antiporter subunit G"
                     /protein_id="WP_112274736.1"
                     /transl_table=11
                     /translation="MTVRDWICAVLLLSGALFCLIGAYGVLRLPDVPSRLQAATKPQTL
                     GLLLILAGTAVRLEPRYAVGLVLAGLFQVITAPVLSQLFGRTAYHTGAIEKSTLVTDEL
                     DERLRAERG"
     gene            complement(11673..11939)
                     /locus_tag="FCN18_RS36080"
                     /old_locus_tag="FCN18_36075"
     CDS             complement(11673..11939)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015075 - monoatomic ion transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0034220 - monoatomic ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015785834.1"
                     /locus_tag="FCN18_RS36080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_36075"
                     /product="monovalent cation/H+ antiporter complex subunit
                     F"
                     /protein_id="WP_112274737.1"
                     /transl_table=11
                     /translation="MTVVFAITFGLLGLAGLLILLRLVRGPRTLDRILAIDVLVVLIVA
                     GTSVGMAMSLRGIYIALLVAVALLGFVGSISVVRLVERREEYR"
     gene            complement(11936..12505)
                     /locus_tag="FCN18_RS36085"
                     /old_locus_tag="FCN18_36080"
     CDS             complement(11936..12505)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019815885.1"
                     /locus_tag="FCN18_RS36085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_36080"
                     /product="Na+/H+ antiporter subunit E"
                     /protein_id="WP_206078072.1"
                     /transl_table=11
                     /translation="MRRISPSLLVWLVLVWLMLWGSLDASTAIFGVLLAFAVLLFFPLP
                     VHRWNIFSRPLRLVGLAVYVVWDLVQSAVRLAFDEFRHGSKVKAAIVAVPVLSDVDHVI
                     ASAANVLSLGPGRFVLQIDRTNRIWYVYALGVQSRVSCDKIHDDALDLQVKVMHAYGSA
                     EEARTARSRAEEAKQRRRARTRMESQ"
     gene            complement(12505..14040)
                     /locus_tag="FCN18_RS36090"
                     /old_locus_tag="FCN18_36085"
     CDS             complement(12505..14040)
                     /GO_function="GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA]"
                     /GO_process="GO:0042773 - ATP synthesis coupled electron
                     transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005445264.1"
                     /locus_tag="FCN18_RS36090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_36085"
                     /product="Na+/H+ antiporter subunit D"
                     /protein_id="WP_137097288.1"
                     /transl_table=11
                     /translation="MTVLVALPVLLPLLAAALSLIVMRSPRMQRLIGATVLTAIAVIAG
                     ALLAEADKHGPVVLQLGGYAAPFGITLVADRLAALLLLTSALVTLAVLIFSIGQRITDY
                     GRQTASTAFHPMYLMLCTGVSLAYLTGDLFNLFVAFEIMLASSYVLITRRTTAERVRAS
                     MTYVIVSLTSSLLFITMIALVYAATGTVNLAALPEKIGELDPGVQTSLGLLMVVVFGIK
                     AALVPLHFWLPDSYPTAPAPITAVFAGLLTKVGVYALIRTQTLVFIHDESWTVLLVVAL
                     LTMIVGVLGAIAQNDLNRMLSFLLVSHIGYMLFGLALFTVIGLAGVILYVVHHITVQAA
                     LFLTSGLITRHTGTVSLHAMSGVAKAYPLVAVLFALPALSLAGIPPFSGFVAKIALLQA
                     GAAVGTPAAYAVTAAAVLTSLLTLFAVTKIWVGAFWGKVGEPHPDPDPTDEVTVGTGST
                     SKGMLVATGGLVAVSVLIAVFAGPLADMSERAAADLLDGGAYRTAVLGEAGGD"
     gene            complement(14037..14495)
                     /locus_tag="FCN18_RS36095"
                     /old_locus_tag="FCN18_36090"
     CDS             complement(14037..14495)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005445263.1"
                     /locus_tag="FCN18_RS36095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_36090"
                     /product="Na(+)/H(+) antiporter subunit C"
                     /protein_id="WP_137097289.1"
                     /transl_table=11
                     /translation="MTVNITMAVVLAGLYTVGFYLLMQRSLMRVILGIVILGHGANLFL
                     QVAGGPPGEPVFAGSALIEAMVDPLPQALALTAIVITFALTTFLLALAYRSWALLGHDE
                     VQDDVEDRRIREAERRREGMDESDEPDTEPAEAVAGFEAPEASEEVPR"
     gene            complement(14492..14995)
                     /locus_tag="FCN18_RS36100"
                     /old_locus_tag="FCN18_36095"
     CDS             complement(14492..14995)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019808435.1"
                     /locus_tag="FCN18_RS36100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_36095"
                     /product="MnhB domain-containing protein"
                     /protein_id="WP_137097296.1"
                     /transl_table=11
                     /translation="MAEHNCNTWPRSLLLEVCARIVFPTVLMVSVYLLFAGHHDAGGGF
                     SGGLVAGLAFVLRYVAGGSAELAATVRIRPPVVIGSGLSIAVLTALVPALVGQPVLSSA
                     IWKLSLPVLGELKFTTNLFLDIGVYLLIVGVVIDLLRTVGAGTELGGPGLDDETLEREE
                     VERT"
     gene            complement(15067..17409)
                     /gene="mbhE"
                     /locus_tag="FCN18_RS36105"
                     /old_locus_tag="FCN18_36100"
     CDS             complement(15067..17409)
                     /codon_start=1
                     /gene="mbhE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005455559.1"
                     /locus_tag="FCN18_RS36105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_36100"
                     /product="hydrogen gas-evolving membrane-bound hydrogenase
                     subunit E"
                     /protein_id="WP_137097290.1"
                     /transl_table=11
                     /translation="MLTAIAAHFVLAAFLPLIARRWGRAAFVVGALAPAATLVFALSRA
                     SGALAERHPVETFAWAPNIGLEFTTRFDELALLMIVLVSGIGALVLCYYACYAKPGDRA
                     VSRDSSLLVLFAGSMLGLVLADDVISLYIFWELTTVCSFLLVGGEGLTRKLRKSATQAL
                     LVTSLGGLAMLLGLLLLATAAGTTRISEIIANPPGGGVVTAAVLLILLGAFTKSAQVPF
                     HPWLPGAMVAPTPVSAYLHAAAMVKAGVYLVARFAPGFSDLPAWWLPIVVLGLWTMVLG
                     GFRALRQHDLKTLLAYGTISQLGFLMVLVGAGTWIAALADVTLVLAHGLFKSALFLTVG
                     IIDKRTGTRDIRELSGLGARWPALTVFATLAVLSMAGFPPLLGFVGKEAAIEGLLHGEP
                     KDLLLLAGVVLGSVFTVAYSLRFLVGAFGARPTVAPTEAPPSGTVMTTIVGIPAVAGLV
                     LAFVPGLVEPLLAGYADAYSANPPDYHLGLWHGFKLPLLLSIAIIIAGYLLHRTALAPR
                     LAGWVPGPLHAQRGYQASVDGLVALAQSVTGRLQAGSLPIYLGVILVTMVAVPGAGLLS
                     GIETPVDLRAWDSLLQVPLAALVLVAAGTVVLARRRLTAVLLTGVVGYGIGALFIVDGG
                     ADLALAQFLVESLTLVVFVFVIRRFPPRFVDGRPYFPRARWVKAGLAAVAGTFVAVLAV
                     LFSGSRQGMPEASRFYAENAESATGATNVVNAIIVDFRAFDTIGEIAVLAIAATGAASL
                     ILARARQRPSGGYVPEDAGSERTEVKQ"
     gene            17554..18036
                     /locus_tag="FCN18_RS36110"
                     /old_locus_tag="FCN18_36105"
     CDS             17554..18036
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020640229.1"
                     /locus_tag="FCN18_RS36110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_36105"
                     /product="cation:proton antiporter regulatory subunit"
                     /protein_id="WP_112274748.1"
                     /transl_table=11
                     /translation="MNVEVTPLPGIGVRKDFAIGNGRRVGVVTQRDGKIELIVSKSDDP
                     DACLASLPLTAEEAGALANLLGAPQLVAQLTEEHRELPGINTKQLPIKAGSPFDGRTLG
                     DTAIRTRTGVSVVAVMRAGQVHPSPTPDFTFTAGDLLVAVGTAEGLEAAFKILKHG"
     gene            18041..19237
                     /locus_tag="FCN18_RS36115"
                     /old_locus_tag="FCN18_36110"
     CDS             18041..19237
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1117:
                     sodium/hydrogen exchanger"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016335355.1"
                     /locus_tag="FCN18_RS36115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_36110"
                     /product="cation:proton antiporter"
                     /protein_id="WP_137097292.1"
                     /transl_table=11
                     /translation="MDHTALELIELGAVFFALGALGRLAGRIGLSPIPLYLVGGLCFGQ
                     GGVLPLGDIGEFTQIAGEIGVVLLLLLLGLEYSAAELFTGLKRSWMAGVLDIVLNAAPG
                     AAVALLLGWGPVGALVMAGVTYISSSGIIAKVLGDLGRLGNRETPVVLSVLVFEDLAMA
                     VYLPILTAVLGGISFLGGLQAVGISLAVITVVLVVALRYGRFVSAIVDSEDREVFLLKV
                     FGAALLVAGFASALQVSAAVGAFLLGIAISGSTAENATRLLEPLRDVFAAVFFVVFGLN
                     TNPASIPPVLAWAVVLAVVTTLTKIATGWWAARRAGIGRLGQARAGAALVARGEFSIVI
                     AGLAVSAGAVEGELAALATTYVLLMAVLGPIAARVVEPVARALQRKTTGLTRTAGDTP"
     gene            complement(19380..20120)
                     /locus_tag="FCN18_RS36120"
                     /old_locus_tag="FCN18_36115"
     CDS             complement(19380..20120)
                     /EC_number="5.4.99.-"
                     /GO_function="GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1154: Pseudouridine synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009155058.1"
                     /locus_tag="FCN18_RS36120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_36115"
                     /product="pseudouridine synthase"
                     /protein_id="WP_112274750.1"
                     /transl_table=11
                     /translation="MRSDQPEGVRLQKVLAQAGVASRRASEELIARGRVSVDGEVVREQ
                     GRRVDPDTAVIHVDGLRVILRDDLVYFAFNKPKGVHSTMTDDQGRPCVGDYVRERRERL
                     FHVGRLDAETEGLLLLTNDGDLAHRLMHPSFHVPKTYLAEVDGTVPRGLGKRLRAGVEL
                     EDGPVKADEFRVKDVRPGRTLVEVVLHEGRKHIVRRLLAEVGHPVRKLVRTAVGDVQLG
                     NVKQGALRPLNRAEIGSLYRAVEL"
     gene            complement(20110..20961)
                     /gene="scpB"
                     /locus_tag="FCN18_RS36125"
                     /old_locus_tag="FCN18_36120"
     CDS             complement(20110..20961)
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /GO_process="GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="scpB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007026391.1"
                     /locus_tag="FCN18_RS36125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_36120"
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="WP_228714309.1"
                     /transl_table=11
                     /translation="MSEPDTEQVTTGAEPEPRPDPAQEPDPVPRREAEAAPEPVPLDID
                     AEDDATAENGPHGHAGRSERDPGAPGTTDDGDDPEAAQGEESGDTSLVAVAADRALPDL
                     TSYDALVSALEALLLVVDTPVDEEVLAGAVDQPVDRVTETLRSMAGDYADRASGIDLRR
                     VGEGWRFYTRDTYAPFVEKMLLDGQRSKLTRAALETLAVIAYRQPVTRSRVAAVRGVNV
                     DGVIRTLVARGLIEESGADPETGGTLYVTTELFLERLGLSSLNDLPPIAPLLPEVDSID
                     EI"
     gene            complement(20958..21833)
                     /locus_tag="FCN18_RS36130"
                     /old_locus_tag="FCN18_36125"
     CDS             complement(20958..21833)
                     /GO_process="GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /GO_process="GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009155060.1"
                     /locus_tag="FCN18_RS36130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_36125"
                     /product="ScpA family protein"
                     /protein_id="WP_112274751.1"
                     /transl_table=11
                     /translation="MEEGAPPQPAPEVPVPETPEEGGSASRFKVRLANFEGPFDLLLQL
                     ISQHQLDVTEVALHQVTDDFIAYTRALGAEWDLDEVTEFLVIAATLLDLKAARLLPAGD
                     VEDEDDLALLEARDLLFARVLQYRAYKQVAALFAELEAGALRRYPRSVALEERYLGLLP
                     EVMLGVTPEKFADLALTVFKPKPPPTVSLDHIHAGRVSVREHAAVLRVRLAETGGATFG
                     ELVSDCEHTIEVVARFLALLELYRESSVQFEQAEALAELHVRWTGGSVDEAAAEAERDR
                     AADAEDEEYG"
     gene            complement(21833..22288)
                     /locus_tag="FCN18_RS36135"
                     /old_locus_tag="FCN18_36130"
     CDS             complement(21833..22288)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016335359.1"
                     /locus_tag="FCN18_RS36135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_36130"
                     /product="cobyrinic acid a,c-diamide synthase"
                     /protein_id="WP_112274752.1"
                     /transl_table=11
                     /translation="MSRRASLPGASELFRRTSSPVFADTPVVPDPAPAGNGHGGSRSNG
                     DGAGSAEGSEPGRGERQLARSATARRGSGRQKHDAKITVYVSGEELLAMEHARLTLRGS
                     HDLAVDRGRIVREAVAVLLADFDQHGEDSVLVRRLRDGQLAAEEAAN"
     gene            complement(22285..23250)
                     /locus_tag="FCN18_RS36140"
                     /old_locus_tag="FCN18_36135"
     CDS             complement(22285..23250)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1157: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020420653.1"
                     /locus_tag="FCN18_RS36140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_36135"
                     /product="ParA family protein"
                     /protein_id="WP_112274754.1"
                     /transl_table=11
                     /translation="MSTSQRPARRVPDDLSRVSIATETGGDSGEYDVTAAEEPNGKDAK
                     NKLGPTGRPRREIPEPPLLERHGPARVVAMCNQKGGVGKTTSTINLGAALAEYGRRVLL
                     VDFDPQGALSVGLGIQPHELDQTVYNVIMERSVDIEGVVRKTRVENVDLLPSNIDLSAA
                     EVQLVAEVGREHTLLRVLRPVMDQYDYVLVDCQPSLGLLTVNALTAADGVIIPLECEFF
                     SLRGVALLIDTIEKVRERLNPKLDITGILATMFDPRTLHSKEVMARVVEAFGDTVFDTV
                     INRTVRFPETTVAGEPITRWAPRSAGATAYRALAREVIAR"
ORIGIN
        1 gatcaacagc ggatccagat tgaacgcagt gaaggtggcc ttcactgcgg ttggccggtg
       61 gcgctcactg ctcgttgtcg ttgccgccct gttccgccag gaagcgctcg aactggctcg
      121 ccagttcgtc gcccgtgggc atcggggtgt tgtcggcgag caggttgccc ttcgcgctcg
      181 ccgcggtgaa cgcgtcgtac tgccgctcca gcgcgctcac cacctcggcc acctcgtccg
      241 actcgcggac ctgacggtcc acctcctcgt cggtgctccg cgccgcctcc cgcagcgcgt
      301 cggacggcag gctgagcccc gtcgcccgcg tgatcgcgtc caggagcgtc agcgccgccg
      361 ccggataccg cgcctgtgcc agatagtgcg gcacgtgcgc ggcgaaaccg atcgcgtcgt
      421 gccccgcctg cccgagccgc agctccagca tcgccgcggc gctgcccgga atccgcacct
      481 cgttgaaaaa cggctggtac tcgtcgacga gctgcgcgcg cgtcgcgtgc gccgtcaggc
      541 ccagcggccg cgtgtgcggc acccccatcg ggatcccctg gaagcccacg ctcagccgca
      601 cctgccagcg ctcgacgaga tggcgcacgg cggcggcgaa ccgttcccac tcgtggtcgg
      661 gctccggccc ggtgaacacc aggaacggcg tcgcgttctc gtcgtgcagc aaccgcaccg
      721 ccagctccgg cgcctcgtag tcggaccagt ggtcgcccga aaaggtcatc gtcggccgcc
      781 gcgaccggta gtcgatcagc cggtccacgt cgaacctcgc caccaccggc ccgtccagct
      841 cctcgaggag gtggtcggcg acggcccggc cggccgcgcc cgcgtcgatg aacccgtcga
      901 agtggtagag cagcaccgca ctgtccagaa cgggaacgtc ggaatccact tcgtacaact
      961 cgcccggatc cgacaccacc gcgtaacctc ctgaccttca gctgtctgtc ccaagcggat
     1021 accaacgcgt ggtgttcctg tttccatccc accacatcga cctgcccccg ggggccgcgt
     1081 ggtggaagat gttcgcgtgc aggagccgaa gacaccccgg accccgaccg tgccgagtcc
     1141 cgagcacgtc gacagcctcg cgaccgtgct cgacctcgtc cgctccggcg tggcgcgaac
     1201 ccggcccgag atcggccgcc actccgggct cggccgcacc gtcgtcaccc agcgcgtcaa
     1261 ccagctcacc gagtgcgggc tgctggagga gggcgcgctc ggcccgtcca gcggtgggcg
     1321 ggcgccgcgc gaactgcgat tccgggcccg cgcgggcctg gtgctcgcgg cggagctggg
     1381 cgccaccagc gtcggcgtcg gcgtcaccga cctcagcggc accgtgctcg ccgagcggga
     1441 ggaggccgcc gacatcgcgc tcggccccga tcccgtgctg gaacgcgtcg agatcctctt
     1501 cgacgagctg ctcgccgaga tccgcgccga acacggcgac gtggccgtgt ggggcatcgg
     1561 catcggcctg ccggggcccg tcgagttcgc gaccggacgg ccgagcgcgc cgccgatcat
     1621 gcccgggtgg gacggctatc cggtgcgtga ccggctcacc gcccgcttcg gcgcacccgt
     1681 gtgggtcgac aacgaggtga acacgatggc gctcggcgaa ctacgcgccg gatccgccaa
     1741 ggggcaacgg gacatcctct acgtcaagat cggcaccggg atcggcgcgg gcctggtgtc
     1801 cggcggacgg ctgcaccgcg gcagccaggg ctgcgcgggc gacatcgggc acgccgccgt
     1861 cgccgacgag gcgaccgtgg tgtgccgctg cggcaacacc ggctgcctcg aggcgtacgc
     1921 cggcggcgcg gcgctcgccc gcgacgggct cgccgccgct caggaggggc gcagcgagtt
     1981 cctcgccggg gtgctggagt ccacgggaac cgtcaccgcg gcggatgtct cccgcgccgc
     2041 gcagagcggc gaccgcacct cggtggagct gctcacccgc gccggcaggc tgatcggcag
     2101 cctcctcgcg acgctcgtca gcttctacaa ccccgcgctc gtgatcatcg gtggcggcgt
     2161 cgccgccgcg ggggacctgc tgctggccgc cgtgcgcgag tcggtctacc ggcgctccct
     2221 gccgctcgcc acgcgggagc tgcgcatcgc gcgctccacg ctgagtgacc gcgccgggct
     2281 cgtgggggcc gcgttcatgg tcatcgacga gctgttcgcc cccgaacggc tcgcccattg
     2341 ggtggcagcg ggaagtccgg ccggagcacc ggaactcgtc aacgtcccat tgcgcgctcc
     2401 cctgctctaa cctggggaga tgcccgatcg cgtctacggg ggccggacgg cggccgatcg
     2461 cagagcagag cgcaggcagc gcctgctgga cgccggtctg gaactgttcg gcaccgaggg
     2521 ctacgtcgcg acctcgatcg agcgactgtg ctccgcggcc ggggtgtcca cgcggaactt
     2581 ctacgaggag ttcaccggac gcgaggcgtt gctgacggcc ttgcacgaca tggtgctgga
     2641 acgcgcgctg aaggccgtcg ccgacgcgtt cgcccgggcg gagaacgagc cgctggccct
     2701 gcggatcgag ctcgccgtgc gcgcctacat cgccaccacc gcggaggacc accgctgggc
     2761 ccgactgtcc tatgtggaga tagtgggcgt cagcgagacg gtggagcggc accggctcgc
     2821 gtggcgcgag cggtgggtgg cgttcctcgt cgccgaggcg cgccgcgccg tcgagcacgg
     2881 ggaggccatg tcgcgcgact tccacctcag cgcggtcgcg ctgatcggcg ccgtcaacga
     2941 gctcgtctac cactgggccg tcggcgacca ccggatcccg ctggacgacg tgatcgccga
     3001 gatcgtacgc atcgcgacgg tgaccctcac cggcccctag gtcacccagc cgcagtgaag
     3061 gccaccttca ctgcgttgag cgcagtgaag gtggccttca ctgcggtcgg tcctgctcag
     3121 ggaagatcgg ttccgtccaa ccaggccgcg aagaaggcgt ccagtggacg gcccgcgtgg
     3181 cgggcggcga gcgcggtgaa ctggtccgtg gtcaccgtcg cgtggcggtg ggtgtccgtc
     3241 cacgcgcgca gcagcccgaa gaaggcctcg tcgccgagct cgccgcgcag cgcgtgcagc
     3301 agcagcccgc ccttcttgta cacgccctcg tcgaacatcc gggccacacc gggatccgcg
     3361 agccgaagcc ctggccgccc cgccagcacc ccgcgccagt accgcgcgtg ctcgtcggcg
     3421 gactgcccgc ccgacgcctg cgaccacagc cattccgcgt aggtcgcgaa tccctcgttg
     3481 agccagatgt gccgccagcc ggccacggtg aggctgttgc cgaaccactg gtgcgcgagc
     3541 tcgtgcacga cgagccgctc gtgggtgcgc ctgccgtcga cgtggttggc gccgaagacc
     3601 gccatcccct gcgcctccac cggatcgtcg agctcgtcgt cggtgaccac cacgacgtac
     3661 tcctcgaacg ggtacgggcc gaagtgctcc gccagcacct ccagcatcct cggctgccgg
     3721 gcgaagtcgg tctccgcgcg cgcccgcagc cccggcggca cggcgagccg ctgcgccggg
     3781 ccgggctcca gctcggtgta gcggccgatc tgcacgctca tgaggtacgt ggccgtcggc
     3841 gcgtgctgct cgtagaccca cgtcgtggtg ctcgccgacc gctgccggga gaccagcgtg
     3901 cccgtgacgt acaccgagta cgccgacgcc gtcgtcagcg ccacgcggta cgtggccttg
     3961 ccggaggggt ggtcgtcgca cgggaaccac gacggcgcgc cgatcggctg cgcggcgacg
     4021 agcacgccgt cgctgagctc gtcccagccg atctcgtccc agtgccgcga cgcgagcggg
     4081 cgcgggttgc cggagtagcg cacctcgacg gtgaactcct cgccctcggc gaggggcagc
     4141 gcgggtgtga tggcgagctt gtggccgcgg tgcgcgtacc gcgcgggcct gccgcccacg
     4201 aacaccctgc ccaccttcag gcccgcgagg tcgaggctca accgggacag cgcctgggtc
     4261 gcgacggcct cgatccggcc cctgccggag agccggttcg cgccgatccg gtagtccagc
     4321 tcgaggtcgt agtgccggac gtggtaaccg ccgttgccgt gctccggcag atacgcgtcg
     4381 cccgacgtgg cggctcccgg cgctgcggac gacctcatca cgccgcgctc accgccaggc
     4441 ggcgatggcg ttgccctgcc accgcgtgtc ggccggcacc acatcacctc gcgtcaccag
     4501 cgagccgggg ccgatcgtcg tgcgggcgcc gatgccggcg ccgggcagca cgatgccgtg
     4561 cgggccgagc gtcgcgccct cgtcgagcac caccgtgtcc atgctcatga tccgatcatg
     4621 gaacaggtgg gtctgcacaa cacaaccccg gttgacggtc gcgccgtcgc cgatgcgcac
     4681 gaggtcggac tcgggcagcc agtacgtctc cagccacgcc ccgcgcccga tccgcgcacc
     4741 catgctccgc agccatgccg aaagcagcgg tgtgccgccg agcgagccga cgagccacgg
     4801 cacggcgagc acctccacga aggtgtcggc cagctccgcg cgccacacga acgagctcca
     4861 cagtggacgt tccgagacgc ggaagcggcc aaccagagcc catttcgcga cggtcgcggt
     4921 cacggcggcg agcgcgcctg ccgcgagcag gacgacgccg gacagcagcg cggccaccac
     4981 gagccccagg ctcgcggtca gcgcgacgag cgcggcgacc acgagcaccg ccagcgcgac
     5041 cccgcacatc accggcacca cccggcacag ctccacggcg gcacgcgcga cgcgcagccg
     5101 ggcaggcggg tcgaacgtgc ggctggtgtc ggcgtcctcg accgaccggc gcagcggcat
     5161 cggcggcatg ccgagccacg acgagccctt cttcgccttc ggcggcgtgg acgagagcac
     5221 cccgaccagc ccgcgcttgg gcaccgaacg gcccggcgct gtcatgccgg agttgccgag
     5281 gaaagcctgc ttgccgatgc gcgcgggggc cacgtgcagc cagccgtgcc ccagctcgta
     5341 ggtggccacc atggtgtcgt cggcgaggaa cgccccgctg tcgatcttgg tcatcttcgg
     5401 caccgcgagc accgtggacg cctcgacgcc gcggccgacc ctcgcgccga gcaggcggag
     5461 ccacacgggc gtgaacaggc tggcgtacaa ggggaacagc ccggcccgcg cggagtccat
     5521 cagccgctcg gtggcccaca cccgccaggc gccgcggctg tgcaccgggt ggtagccctc
     5581 gcgcaggccg atcccgaggg cccgcactcc acagagcacg agcagcgcgt acgcggcgag
     5641 gtaggcgacc gtcgcgaccg ggacggcggc cagtgccgcg ccgagcgcgg aaccgggcgc
     5701 tcgcccggcg accgcaccgc cgagcaccgc gagcgcgggc accgccgcga tcgccggcag
     5761 caggccaagc agcaccgagg taacgccgta gaccgccacc caccggcgtg agcggcgggg
     5821 cgcctccgac ggccattgcc tgctcgcctt gccctcgcgg cgcgcgggcg accccgccca
     5881 gcgctgtccc gcgggcacgc tgccgaggac ggtggacccc gccgcgatct ccgcgtgctt
     5941 gccgacgcgg gcgccaggca gcagggtgct ccgcgccccc acgcgcgcgc ctgcgccgac
     6001 gcggatcttg ccgatgtgca cgacgtcgcc gtcgacccag tagccggaga ggtcggcctc
     6061 tggctccacc gccgctcccc tgcccagctt gagcagcccg gtcaccggcg gctgggagtg
     6121 caggtcgacg tcacggccga ccttggcgcc cagcgcccgc gcgtagtggg tcatccacga
     6181 cgctcccgcg acggcgttgg cgccgctggc gtcggccagc cgctcggcgg cccacagccg
     6241 caggtgcacc cgcccgccac gcggatgggt acctggccgt acgccgcgta acaacagccg
     6301 ggcaccgccc gccgcgatcg cgatccgccc ggccgggctg aacagcacga gccacgccac
     6361 gccgagcgcc caccatggca ccgagggagc ccacgcgagc ccggcccacc gcgcgagcac
     6421 cgtcgacacg gcggccgcga tcgtggtcca gcgcaacccg gcaagagtga acagcggcag
     6481 caggagcagc gtctgcacca accccgcgcg gcgcggcgtc ggcgccacct cgcggcggct
     6541 ggtggtcgcg tcgccgagcg cgtccagcag ggcggcgagc tcgccgaggc gcgggtgccg
     6601 gtacacgtcg gttaccgaga ccgtggggtg cctcgtgcgg atgcgggaga cgagctgtgc
     6661 cgcggtgaga cttccgccgc cgttgcggaa gaagtcggct gccgcgtcgg tcaccgagac
     6721 gccgaggatc tcgccccatg cctcggcgag ccaggactcc gtcggagaca acgattcctt
     6781 ggtatccact gtggacagcg gccagggcag cgccgcgcgg tcgaccttgc ccgaggtccg
     6841 cgtcggcagg tcgcctacca cggcgagcag cggcacgagc gcggcgggca gctgttcccg
     6901 cagccgggac acggcgccgt cgtggtcgaa gtcctcccga ggcacgacgt acccgacgag
     6961 aacctggttg cccgccttgg tggtgcggat ggcggccgcg ccgcccgcga cgccgggcag
     7021 cgcctgcagc gccgcgtcca cctcaccgag ctcgatccgg cggccaccga gcttgatctg
     7081 ttcgtcggcc ctgccgagga acagcagccc gtccggctcg gcgcgcacga ggtcgccgct
     7141 gcggtacgcc cgctgccagc cgagtgcggg cagtggcgcg aacttctcgg cgtccttggc
     7201 cggatcgagg tagcgcgcga gccccacccc accgatcacc agctcgccgg actcgcccat
     7261 cgcgaccggc ctgccctcgt cgtcgacgac ggcgagctgc cagcccgcga gcggcagccc
     7321 gatgcgcacc ggaccctcgc cggtgagctg cgcggcgcac gccacgacgg tggcctcggt
     7381 gggtccgtag gtgttccaga cctcgcggcc ctcgacggcc acgcgctcgg ccagctccgg
     7441 cgggcacgcc tcgccgccga agatcagcag ccggacctcc tccagcgcgt cggcgggcca
     7501 cagcgccgcg agcgtaggca cggtcgagac gacggtgatc cgccgctcca ccagccacgg
     7561 gccgaggtcg acgccggtgc gcacgagcgc tctcggcgcg gggaccaggc acgcgccgtg
     7621 ccgccacgcg agccacatct cctcgcacga ggcgtcgaag gcgaccgaca gcccggcaag
     7681 cacgcgatcg ccgggtccga gcggctcgtc ggcgaggaac agctctgcct cggcgtcgac
     7741 gaacgcggcc gcgctcgcgt ggctcacggc gacgcccttg ggcctgcccg tggaaccgga
     7801 ggtgaagatg atccaggcgt cgtcgccggg cgcgggcgcg cccggcgccc cgcccggggt
     7861 cccgcacggc gtgagcgcgc caccgtcgcc gagcacggcg cacaccccgg cctcgccgaa
     7921 cacgagctcg gcccgctcgg cggggtcgtc ggcgtccacc ggcacgtagg cggcgccgag
     7981 cgacagcacc gcgaggatcg cgacgtacag ctcagcggtg cccgacgaga tccggacgcc
     8041 gacgcggtca cccctgccga tgcccgccgc ggcgagcttg ccgcgcacgg tctcgatctc
     8101 ctcggcgagc gcccggtacg tcagcgtctc cgtgccgtcg tcgagcgcag gcgcaccggg
     8161 gtggcgcgcc gcggtctcgg ccaggatgtc cagcagcgtc cgctcgctcg gggcgagacc
     8221 ggaccagaac agcgcacgac ccgcggtggg tgtggcgggc ccggtcgggg cggcgtcgat
     8281 cgcgagagtc acacggcctc acagcagctc atccgggtcg gctccgaatg aggcgcccct
     8341 ttaccggccg accaggatac ccgagggtga acggcaggtt gccgagcggt gtcgcgttgc
     8401 ggacgcagtg aaggccacct tcactgcgtt gaacgcaggc atggtggcct tcactgcgtt
     8461 gggcgcaggc atggtggcct tcactgcaca gggggcctac cgcgacttcc tgggcttctt
     8521 ctcgcgcacg cggacgttga tccgaaccgg actgccctgg aaaccgaagc gttcccggaa
     8581 cttccgctcg atgaagcggc ggtagccggc ctccagaaaa cctgtggtga acaacacgag
     8641 cgtcggcggc cggatccccg cctgcgtcgc gaagagcacc ttcggctgct tgccgccgcg
     8701 caccgggggc ggcgtggcgg ccacgaggtc ggagagccag ccgttgagct gcccggtcgg
     8761 cacgcgctgg tcccacgacg cgagcgccgt gcgcagcgcg ggcgccagct tgcggacggc
     8821 gcggcccgtg agcgcggaga cgttgacccg ctccgcccac ggcacgcgga ccagtccccg
     8881 gtccagctcg cggtcgagct ggtgccgccg gtcctcgtcc acgagatccc acttgttgaa
     8941 ggccagtacc agcgcgcggc ccgcctcggc gaccagcgtc accacccgca ggtcctgctc
     9001 ggacaccggc tcgctggcgt ccagcagcac gatcaccacc tcggcggcgt cgatcgcggt
     9061 ccgcgtgcgc agggacgcgt agtactccat gccgctcgcg gtctgcacgc gcttgcgcag
     9121 gcccgccgtg tcgacgaagc gccacagctg cccgtccagc tccaccagcg agtcgacggg
     9181 gtcgacggtg gtgcccgcga ccgagtccac caccgcgcgc tcctcgccgg tgagcttgtt
     9241 gagcaggctg gacttgccga cgttgggctt gccgacgagc gcgacgcggc ggggtccgcc
     9301 cgcgacgcgg tcggcgtccc tcggcgcctc gggcagcgcg ttcacgatcg cgtcgagcag
     9361 atcaccggag ctgcggccgt gcagtgcgct caccggatgc ggctcgccga gcccgagcga
     9421 ccacagcgac gcggtctccg cgagcaggcg ctcgtcgtcg accttgttgg ccgccagcag
     9481 cacgggccgc ttcgaacgcc gcagcacctt cgcgaccgcc tcgtcggtgg ccgtcgcgcc
     9541 cacggcggcg tcgacgacga gcagcacggc gtccgaagtg gacatcgcca gctccgcctg
     9601 tgccgccacg gagccccgga gcccggtggc gcccggctcc cagccgccgg tgtcgacgac
     9661 ggtgaaccgg cgcccgttcc acagcgcgtc gtaggcgacg cggtcgcgcg tcacgcccgg
     9721 cacgtcctgc acgacggcct cgcggcggcc caggatccgg ttcaccaggg tggacttgcc
     9781 cacgttcggc ctgcccacca cggccagcac cggctgtgcg agctcggcgt cgtcgtcggg
     9841 ctctccctcg gcgccctccg tgtcggcggc gaggaactcc gcctcgtcgg accaggtgcc
     9901 gtctgcttcg gtcattgtct ctgcttctct tctcgttgcc ggtcaagctc ttcgacgagg
     9961 gcggcgagcg tccccctgat gcgctcggtg ccctcggcca gcgcggcgcg tcccctgccg
    10021 acgtccactg tgaacggttc gccgacgagc acgtccaccg tgggccggaa ccgtcgtctg
    10081 cccgtggggt tgagcgtccc gcgcaccgcc acgggcacca cgaccgcgcc cgacacccgc
    10141 accagccacg cggcgccctg ctgggcctgt gccacgtcgc ccgcgccccg cgtgccctcg
    10201 gggaacaccc ccacgagccc gccgtcgcgc agcacttcgg tcgccgtgcg cagcgcctcc
    10261 cggtccggca cgccgcgctt caccggaacc tgcccgatgc ggcgcagacc ccagcccgcc
    10321 gggcccgaga acatctcctc cttgacgagg aacaccgagc gcctcggcaa cattccgaag
    10381 atgagctgcg gctcgatcat cgagctgtgg ttggcgacca gcacgactgg gcccgtgcgc
    10441 ggcacgcggg cggcgccgtg cacgcggatc cggtaggcgg gccggtagag gtaccgggcg
    10501 atcaccctgc ccacgtcgtg cagccagggc gtcgcgcccc gggggagtcc ggtcaccggc
    10561 tggcctccgc gaactcgccg ccgagcaggc ccctcctgct ggccagctcg ctcagcgccg
    10621 tgatcacctg ctcgatcgac agctcggagg tgtcgaacac cacggcgtcc tccgccgcgc
    10681 gcaggggcga gacggtcctg gtggagtcga gctggtcccg gcgctccacc gacgcccgcg
    10741 cgtgctcggg cgtcgagtcc ctgcccgcgg cggagtcctg cgcgctgcgc cgcgcggccc
    10801 tcacctcggc cgacgcggtg aggaagacct tgagcggggc cccgggcgcc acgacggtgc
    10861 cgatgtcgcg gccgtcgacc acgatgccgc ccaccgagcc cagcacggcc tcgatgatct
    10921 cccgctgccc ggcgacgagc acctgccgca cctcggggac ggccgagacg ggcgacacgg
    10981 ccacgttgac ccgctcggtg cggatctcct cgccgacgtc ctcgccgttc agctgcgcgc
    11041 gcggattgtc ggggtcggtt ccgacaccca cctgtacctg gctggtcagc gcggcgacgg
    11101 cggcggcgtc ggtgggatcg atgcccgcgc gcagcaccgc gagggtgacg acgcggtaca
    11161 tcgcgcccgt gtcgaggtag ccggcgccca gcttggcggc cagcttgcgc gcgaccgtgg
    11221 tcttgccggt tcccgatggg ccgtccagag cgaccacgcc gcgtagggct cccgccaccg
    11281 actgttctcc ctcgctaatc gtcgtgcctt gcgagggtcc attctgcctt ccggtcagcc
    11341 gcgctccgca cgcaggcgct cgtccagctc gtcggtgacc agcgtggact tctcgatggc
    11401 gccggtgtgg taagcggtgc ggccgaacag ctgggacagc acgggcgcgg tgatcacctg
    11461 gaacaggccg gcgagcacga ggcccaccgc gtaccgcggc tccagccgca cggcggtgcc
    11521 ggcgaggatc agcagcaggc cgagcgtctg cggtttggtg gccgcctgca gcctgctggg
    11581 cacgtcgggc agccgcagca cgccgtacgc gccgatcaag cagaacagcg ccccagagag
    11641 caggagcacc gcacagatcc agtcgcgcac ggtcaccggt actcctccct gcgctcgacg
    11701 aggcgcacca cggagatcga gccgacgaac ccgagcaggg ccacggccac cagcagcgcg
    11761 atgtagatgc cgcgcagcga catcgccatg cccacggagg tcccggccac gatgagcacc
    11821 acgagcacgt cgatcgcgag gatccggtcg agcgtgcgcg ggccgcggac cagccgcagc
    11881 aggatcagca gcccggcgag gccgagcagg ccgaaggtga tcgcgaagac gacggtcatt
    11941 gggactccat ccgggttcgg gcgcggcgcc gctgcttggc ctcctccgca cgggaccgcg
    12001 ccgtgcgggc ctcctcggcg gagccgtacg cgtgcatgac cttcacctgc aggtcgagcg
    12061 cgtcgtcgtg gatcttgtcg caggacacgc gcgactggac accgagcgcg tagacgtacc
    12121 agatccggtt ggtccggtcg atctgcagca cgaaccgtcc ggggcccagc gagagcacgt
    12181 tggccgcgga ggcgatcacg tggtccacat cggacagcac gggtaccgcc acgatcgccg
    12241 ccttgacctt ggagccgtgg cggaactcgt cgaacgcgag ccgcaccgcc gactgcacca
    12301 ggtcccacac gacgtacacg gccaggccca ccaggcgcag cggacggctg aagatgttcc
    12361 accggtgcac cggcagcggg aagaacagca gcaccgcgaa cgcgagcagc actccgaaga
    12421 tcgcggtgct cgcatccagc gagccccaga gcatcagcca caccagtacg agccagacca
    12481 gcagcgaggg cgagatcctg cgcatcaatc accacccgcc tcgcccagca cggcggtccg
    12541 gtaggcgccg ccgtcgagca ggtccgcggc cgcgcgctcg ctcatgtccg ccagcggacc
    12601 cgcgaacacg gcgatcagca cgctgaccgc caccagccct ccggtggcca cgagcatgcc
    12661 cttcgacgtc gagccggtgc ccaccgtcac ctcgtcggtc ggatctggat cgggatgcgg
    12721 ctcgccgacc ttgccccaga acgcgcccac ccagatcttg gtcaccgcga agagcgtcag
    12781 caggctcgtc agcacggccg ccgcggtgac ggcgtaggcc gcgggggtcc ccacggccgc
    12841 gcccgcctgc agcagcgcga tcttggcgac gaaccccgag aacggcggga tgccggcgag
    12901 actcagcgct ggcagtgcga acaacaccgc caccagcggg tacgccttgg ccacaccgga
    12961 catcgcgtgc agcgacacgg ttccggtgtg ccgcgtgatc agaccgctgg tgaggaacag
    13021 cgccgcctgc accgtgatgt ggtgcaccac gtacaggatc acgcccgcca ggccgatcac
    13081 ggtgaacagc gccaggccga acagcatgta gccgatgtgg ctgacgagca ggaaggacag
    13141 catccggttg aggtcgttct gcgcgatcgc gccgagcacg ccgacgatca tcgtcagcag
    13201 cgcgacgacc agcagcaccg tccagctctc gtcgtggatg aacaccagcg tctgggtgcg
    13261 gatcagcgcg tacacaccca ccttggtgag caggcccgcg aacaccgcgg tgatcggcgc
    13321 cggggcggtc gggtagctgt ccgggagcca gaagtgcagc ggcacgagcg cggccttgat
    13381 cccgaacacc acgaccatga gcagcccgag gctcgtctgc actccggggt cgagctcgcc
    13441 gatcttctcc ggcagcgccg cgaggttcac ggtgcccgtc gccgcgtaca ccagcgcgat
    13501 catggtgatg aacagcagcg acgacgtgag gctcacgatc acgtacgtca tgctggcccg
    13561 cacgcgctca gccgtggtgc gccgcgtgat cagcacgtac gacgaggcca gcatgatctc
    13621 gaaggcgacg aagaggttga acagatcgcc ggtgaggtag gccagcgaga cacccgtgca
    13681 cagcatcagg tacatcgggt ggaacgcggt ggacgcggtc tgcctgccgt agtcggtgat
    13741 gcgctggccg atcgagaaga tcagcacggc gagcgtcacc agcgccgagg tcagcagcag
    13801 cagcgcggcg agccggtcgg cgaccagcgt gatcccgaac ggcgccgcgt agccgccgag
    13861 ctgcagcacg acggggccgt gcttgtcggc ctccgcgagc agcgcgccgg cgatcaccgc
    13921 gatggcggtg agcacggtgg cgccgatcag ccgctgcatg cgaggcgagc gcatcacgat
    13981 cagcgacagt gcggcggcga gcagaggcag cagcaccggc aatgcgacga ggacggtcac
    14041 ctcggcacct cctcactcgc ctcgggggcc tcgaacccgg cgaccgcctc cgcgggctcg
    14101 gtgtcgggct cgtcggactc gtccatgccc tcgcgccgcc gttccgcctc gcggatccgc
    14161 cggtcctcga cgtcgtcctg cacctcgtcg tggccgagca gcgcccacga gcggtacgcc
    14221 agtgccagca ggaacgtggt gagcgcgaag gtgatgacga tggcggtgag cgcgagggcc
    14281 tgcggcagcg ggtcgaccat cgcctcgatc agcgcggagc ccgcgaacac cggctccccc
    14341 ggcgggccgc ccgcgacctg gaggaacagg ttcgcgccgt ggccgaggat cacgatgccg
    14401 aggatcacgc gcatcaggga acgctgcatg aggaggtaga agccgaccgt gtagagcccc
    14461 gcgagcacca cggccatggt gatgttcacg gtcacgtgcg ctccacctcc tcgcgctcga
    14521 gcgtctcgtc gtcgagcccg ggtccgccca gctccgtgcc cgcaccgacc gtgcggagca
    14581 ggtcgatgac gacgccgacg atcagcaggt acaccccgat gtcgaggaac aggttggtgg
    14641 tgaacttcag ctcgccgagc actggcaggg agagcttcca gatcgccgag gacagcacgg
    14701 gctggcctac cagtgcgggc acgagcgccg tgagcaccgc gatgctgagc ccgctgccga
    14761 tcaccaccgg cggcctgatc cggacggtcg cggcgagttc cgcgctgcca ccggccacgt
    14821 accgcagcac gaacgccagc ccggcgacga gcccgccgct gaacccgccg cccgcgtcgt
    14881 ggtgcccggc gaagagcagg tacaccgaca ccatcagcac ggtcgggaag acgatgcggg
    14941 cgcagacctc gagcagcagc gagcgcggcc aggtgttgca gttgtgctcg gccatcagcc
    15001 accggtcgcg cggccggtcc cactccgccc acggcacccg ctcgagttcg cggtccggtt
    15061 cggtgctcac tgcttcacct ccgtccgttc gcttccggcg tcctcgggca cgtagccgcc
    15121 ggatggccgc tgtcgcgcgc gggcgaggat caggctcgcc gcgcccgtcg ccgcgatggc
    15181 gagcaccgcg atctcgccga tcgtgtcgaa ggcgcggaag tcgacgatga tcgcgttgac
    15241 gacgttggtg gcgcccgtcg cactctcggc gttctcggcg tagaaccggc tcgcctcggg
    15301 catgccctgc cggctcccgg agaagagcac cgccagcacg gcgacgaacg tgccggccac
    15361 ggccgcgagt ccggccttga cccagcgggc cctggggaag tacggccggc cgtcgacgaa
    15421 gcgcggcggg aaccgccgga tcacgaagac gaacaccacg agggtgagcg attcgacgag
    15481 gaactgtgcc agcgcgaggt cggcgccacc gtccacgatg aacagcgcgc cgatgccgta
    15541 gccgaccacg ccggtgagga gcacggcggt gagccgccgc cgcgcgagca ccaccgtgcc
    15601 ggccgccacg agcaccagtg ccgcgagcgg cacctgcagc agcgagtccc acgcgcgcag
    15661 gtccacgggt gtctcgatgc ccgaaagcag ccccgccccg ggcacggcga ccatcgtcac
    15721 gaggatcacg ccgagataga tgggcagcga acccgcctgc aggcgcccgg tcacggactg
    15781 ggcgagcgcg acgagaccgt ccacgctggc ctggtagccg cgctgggcgt gcagcggccc
    15841 cgggacccag cccgcgagcc tcggcgcgag cgccgtacgg tgcagcaggt aaccggcgat
    15901 gatgatcgcg atgctcagca gcaacggcag cttgaagccg tgccagagcc cgaggtggta
    15961 gtcgggcgga ttcgccgagt aggcgtcggc gtacccggcg agcagcggct ccaccagccc
    16021 gggcacgaac gcgagcacga ggcccgcgac cgccgggatg ccgacgatcg tggtcatcac
    16081 ggtgcccgac ggtggggcct cggtgggcgc gaccgtcggc cgggcgccga acgcgcccac
    16141 caggaaccgc aggctgtagg ccacggtgaa caccgagccg agcaccacgc ccgcgagcag
    16201 cagcaagtcc ttcggctcgc cgtggagcag gccttcgatg gccgcctcct tgccgacgaa
    16261 gccgagcagc ggcgggaatc cggccatgga cagcacggcg agcgtcgcga acaccgtcag
    16321 cgcgggccag cgcgcgccga gcccggacag ctcgcggatg tcgcgggtgc cggtgcgctt
    16381 gtcgatgatg ccgacggtga ggaacagcgc cgacttgaac agcccgtggg cgagcaccag
    16441 cgtcacgtcc gcgagcgccg cgatccacgt gcccgcgccg acgagcacca tcaggaagcc
    16501 gagctggctg atggtgccgt acgccagcaa cgtcttgagg tcgtgctgcc gcagcgcgcg
    16561 gaagccgccc agcaccatcg tccagagccc gagcaccacg atcggcaacc accaggccgg
    16621 caggtccgag aagccggggg cgaaccgcgc gacgaggtag acaccggcct tcaccatcgc
    16681 ggccgcgtgc aggtacgcgc tcaccggcgt cggcgccacc atcgcgccgg gcagccaggg
    16741 gtggaagggc acctgcgcgg acttggtgaa cgcgccgagc aggatcagca gcaccgccgc
    16801 cgtcaccact ccgccgcccg gcgggttcgc gatgatctcc gagatgcggg tggttccggc
    16861 cgccgtggcg agcaggagca ggcccagcag catcgccaga ccgccgaggc tcgtcacgag
    16921 cagcgcctgg gtcgccgact tgcgcagctt cctggtgagg ccctccccgc cgaccagcag
    16981 gaaggagcac accgtggtga gctcccagaa gatgtacagc gagatgacgt cgtcggcgag
    17041 aacgaggccg agcatggagc ccgcgaacag caccagcagt gacgagtcgc ggctgacggc
    17101 tcggtcgccc ggcttggcgt agcacgcgta gtaacacagc accagcgcgc cgatgcccga
    17161 cacgagcacg atcatcagca acgcgagctc gtcgaagcgc gtggtgaact ccagaccgat
    17221 gttcggggcc cacgcgaacg tttccaccgg gtgtcgctcg gccagtgcgc cgctcgcccg
    17281 gctcagcgcg aagacgagcg tcgccgcggg ggccagcgca ccgacgacga acgcggccct
    17341 cccccaccgg cgcgcgatca acggcaggaa cgccgcgagc acgaaatggg ccgctatggc
    17401 cgtcagcacc cggtctcacc cctccctgct agccacccga caggtcctga tcgtacggac
    17461 ccccctgaac ggcccgcgcg ttgaccgaaa tggacagtcc agccaaaccg gtcgggagct
    17521 gtttcgagtg ccgaatgggt taccttggga tacgtgaacg tcgaagtaac tcccctgccg
    17581 ggaatcggcg tccgtaagga cttcgccatc ggcaacggcc gcagggtcgg cgtggtcacc
    17641 cagcgggacg gcaagatcga actgatcgtc tcgaagtccg acgatcccga cgcgtgcctg
    17701 gcctcgttgc cactcacggc cgaggaggcg ggcgcgctgg cgaacctgct cggggcccct
    17761 cagctcgtgg cacagctcac cgaggagcac cgggagctgc cgggcatcaa caccaagcag
    17821 ctgccgatca aggccggctc gccgttcgac ggccgcacgc tcggtgacac cgcgatccgc
    17881 acccgcaccg gcgtgtcggt ggtcgcggtg atgcgcgcgg gccaggtgca cccgtcgccg
    17941 accccggact tcaccttcac cgcgggcgac ctgctcgtgg cggtcggcac ggcggagggt
    18001 ctcgaagccg ctttcaagat cctcaagcac ggctgagtac gtggatcaca cagcactcga
    18061 actgatcgaa ctaggcgccg tctttttcgc gctgggcgca ctcggcagac tcgcgggccg
    18121 gatcggactc tctccgatcc ccctgtacct ggtgggtggc ctgtgcttcg gccagggcgg
    18181 ggtgctgccg ctcggcgaca tcggtgagtt cacgcagatc gccggtgaga tcggcgtcgt
    18241 cctgctgctg ttgctgctgg gcctcgagta ctccgcggcc gagctcttca cggggctgaa
    18301 gcggtcgtgg atggccggtg tgctcgacat cgtcctcaac gccgcgccgg gggccgccgt
    18361 ggcgctgttg cttggctggg gcccggtcgg cgcgctggtg atggcgggcg tcacctacat
    18421 ctcctcgtcg ggcatcatcg ccaaagtcct cggcgacctc ggccggctcg gtaaccgcga
    18481 gacgccggtg gtgctttcgg tgctggtgtt cgaggacctc gcgatggccg tgtacctgcc
    18541 gatcctcacg gccgtgctgg gcggcatcag cttcctcggc ggcctgcagg cggtcggcat
    18601 ctcgctcgcc gtgatcaccg tcgtgctcgt cgtcgcgctg cgctacggcc gcttcgtctc
    18661 cgcgatcgtg gacagcgaag accgcgaggt gttcctgctc aaggtgttcg gcgcggcgct
    18721 gctcgtggcc gggttcgcct cggcgctgca ggtgtcggcc gcggtgggcg cgttcctgct
    18781 gggcatcgcg atctccgggt cgacggccga gaacgccacg cggctgctgg agccgctgcg
    18841 cgacgtgttc gccgccgtgt tcttcgtggt gttcggcctc aacaccaacc cggcctcgat
    18901 cccgccggtg ctggcctggg ccgtcgtcct cgccgtcgtg accacgctga ccaagatcgc
    18961 caccggctgg tgggcggccc ggcgcgcggg catcggcagg ctcggccagg cccgcgcggg
    19021 tgccgcgctg gtcgcgaggg gtgagttctc gatcgtcatc gccggcctcg cggtgagcgc
    19081 gggcgccgtg gagggcgagc tcgccgcgct ggcgacgacc tacgtgctgc tgatggccgt
    19141 gctcggcccc atcgcggcgc gggtggtgga gccggtggcg cgggcccttc agcgcaagac
    19201 caccggcctc acgcgcacgg ccggtgacac gccgtagcca ccccaccccg gctgcagtga
    19261 aggccaccat cactgcgttg gaatcaacac agcggcgcgc agcgtctccg tttgggtggt
    19321 ggtgggagac gggtgggcgc aggcatggtg gccttcactg cagcccggca gccttggctc
    19381 tagagttcga cggcccggta gaggctgccg atctcggcgc ggttcagcgg ccgaagcgcg
    19441 ccctgcttga cgttgccgag ctgcacgtcg ccaacggcgg tccgcacgag cttgcgcacc
    19501 gggtggccga cctcggcgag caggcggcgc acgatgtgct tgcgcccctc gtgcagcacg
    19561 acctccacca acgtgcggcc cggccggacg tccttcaccc ggaactcgtc ggccttcacg
    19621 ggcccgtcct cgagttcgac gccggctcgc agccgtttgc cgagcccacg cgggacggtg
    19681 ccgtcgacct cggcgaggta ggtcttgggc acatggaacg aagggtgcat gagccggtgc
    19741 gcgaggtcgc cgtcgttggt cagcaggagc aggccctcgg tctcggcgtc gagcctgccg
    19801 acgtggaaga gccgttcgcg ccgttcgcgc acgtagtccc cgacgcaggg cctgccctgg
    19861 tcgtcggtca tcgtgctgtg cacgcccttg ggcttgttga acgcgaagta cacaaggtcg
    19921 tcgcgcagga tcacgcgcag gccgtcgaca tggatcacgg ccgtgtccgg gtccacgcgg
    19981 cggccctgct cgcgcacgac ctcgccgtcg acgctcaccc ggccgcgcgc gatcagctcc
    20041 tcggacgcgc gccgcgaggc cacgcccgcc tgcgcgagca ccttctgcag gcgcacgcct
    20101 tcgggttggt cagatctcat cgatggagtc cacttccggc agcagggggg cgatcggcgg
    20161 caggtcgttc agcgacgaca gccccaaccg ctccaggaac agttcggtcg tcacgtacag
    20221 cgtgccaccg gtctcgggat cggcgccgga ctcctcgatg agcccccgcg cgacgagcgt
    20281 gcggatcacg ccgtcgacgt tcacgccacg caccgccgcg acgcgcgagc gcgtgaccgg
    20341 ctggcggtag gcgatcacgg ccagcgtctc cagcgccgcc ctcgtcagct tcgagcgctg
    20401 cccgtcgagc agcatcttct ccacgaacgg cgcgtacgtg tcgcgcgtgt agaaccgcca
    20461 gccctcgccg acgcggcgca ggtcgatgcc gctggcgcgg tcggcgtagt cgcccgccat
    20521 cgaccgcagc gtctcggtga cgcggtcgac gggctggtcg acggccccgg cgagcacctc
    20581 ttcgtccacc ggcgtgtcca ccacgagcag cagcgcctcc agcgcggaga cgagcgcgtc
    20641 gtaggaggtc aggtcgggca gggcccggtc ggcggcgacg gcgacgagac tggtgtcgcc
    20701 gctctcctcg ccctgggccg cctctgggtc atcaccgtcg tcggtggtcc caggagcacc
    20761 ggggtcacgt tcgctgcgac cagcgtgccc gtggggaccg ttctcagcag tggcgtcgtc
    20821 ctcggcgtcg atgtccagcg gcaccggctc cggcgcggcc tcggcctccc gccgcggcac
    20881 cgggtccggt tcctgcgcgg ggtccggccg cggctccggt tccgccccgg tcgtcacctg
    20941 ctcggtgtct ggctcactca cccgtactcc tcgtcctcgg cgtcggcggc gcggtcacgt
    21001 tccgcctccg cggcggcctc gtcgacgctc ccgccggtcc atcgcacgtg cagctccgcg
    21061 agcgcctcgg cctgctcgaa ctgcaccgac gactcccggt acagctccag cagcgccagg
    21121 aagcgggcca ccacctcgat cgtgtgctcg cagtcggaga ccagctcgcc gaacgtcgca
    21181 ccgcccgtct cggccagccg cacccgcagc acggccgcgt gctcgcgcac cgacaccctg
    21241 cccgcgtgga tgtggtccag cgacacggtg ggcggcggtt tgggtttgaa caccgtgagc
    21301 gcgaggtcgg cgaacttctc cggcgtcacc ccgagcatca cctcgggcag caacccgagg
    21361 tagcgctcct ccagcgccac cgaccgaggg taacgccgca gcgcaccggc ctccagctcg
    21421 gcgaacagcg ccgccacctg cttgtacgcc cggtactgaa gcacgcgcgc gaacagcagg
    21481 tccctggcct ccagcagcgc caggtcgtcc tcgtcctcga cgtcgcccgc gggcagcagc
    21541 cgggccgcct tgaggtcgag cagcgtcgcc gcgatcacga ggaactcggt gacctcgtcg
    21601 aggtcccatt cggcgcccag cgcacgcgtg taggcgatga agtcgtccgt gacctggtgc
    21661 aacgccacct cggtcacgtc gagctggtgc tgtgagatca gctgcagcag caggtcgaac
    21721 ggcccctcga agttggcgag gcgcaccttg aaccgggacg ccgaaccgcc ctcctcgggt
    21781 gtctccggaa cgggcacctc gggggccggc tggggcgggg ccccctcctc catcagttcg
    21841 cggcttcctc ggcggcgagc tggccgtcgc gcaaccgtcg caccagcacc gaatcctcgc
    21901 cgtgctggtc gaagtcggcg agcagcaccg ccaccgcctc ccggacgatc cggccccggt
    21961 ccaccgcgag gtcgtgcgag ccgcgcagcg tcagtcgggc gtgctccatc gcgagcagct
    22021 cctcgccgga gacgtacacc gtgatcttgg cgtcgtgttt ctgcctgccg gagccgcgcc
    22081 gggccgtggc cgaccgcgcg agctgccgct cgccgcgccc cggttcgctg ccctcggcgc
    22141 ttccggcgcc gtcgccgttg gagcgggagc caccgtgccc gttgcccgcc ggggcggggt
    22201 cgggcaccac gggggtgtcc gcgaacaccg ggctgctggt cctgcggaag agctctgacg
    22261 caccgggcag ggaagctcgc ctgctcaccg agcgatcacc tcgcgcgcca gcgcgcggta
    22321 cgccgtcgcg ccggccgacc tgggggccca gcgagtgatc ggctcgccgg ccacagtggt
    22381 ctcagggaat cgcacggtgc ggttgatcac cgtgtcgaac acggtgtccc cgaatgcctc
    22441 caccacgcgc gccatgacct ccttcgaatg cagggttctc ggatcgaaca tggtggcgag
    22501 aatcccggtg atgtccagtt tggggttgag ccgctcgcgc accttctcga tggtgtcgat
    22561 gagcaacgcc acgccacgca aactgaagaa ctcgcactcc agcgggatga tcacgccgtc
    22621 ggccgcggtg agcgcgttga cggtgagcag cccgagcgac ggctggcagt cgactagaac
    22681 atagtcgtac tggtccatca cgggtctcag caccctcagc aacgtgtgct cgcggcccac
    22741 ttcggcgacg agctgcacct cggcggccga gaggtcgatg ttgctcggca gcaggtccac
    22801 gttctcgacc cgcgtcttgc ggacgacgcc ctcgatgtcc accgagcgtt ccatgatcac
    22861 gttgtagacg gtctggtcca gctcgtgcgg ctggatgccg agcccgacgg agagggcgcc
    22921 ctgcgggtcg aagtccacga gcagcacgcg cctgccgtac tcggcaagcg cggcgccgag
    22981 gttgatggtc gaggtggtct tgccgacgcc gcccttctgg ttgcacatcg cgacgaccct
    23041 cgcgggcccg tgcctctcca gcagcggcgg ctcgggaatc tcccggcgcg gacggccggt
    23101 cggaccgagc ttgttcttgg cgtccttgcc gttcggctcc tccgccgcgg tcacgtcgta
    23161 ctccccacta tcgccgccgg tctcggtcgc gatgctcacc cggctgagat cgtccggaac
    23221 gcgccttgcc ggtctctggg atgtcgacat gtggcgaaag ctcctcgttc ggccatggac
    23281 ggcgccagcc ta
//
