LOCUS       NZ_SWMS01000029        20990 bp    DNA     linear   CON 10-DEC-2024
DEFINITION  Prauserella endophytica strain CGMCC 4.7182 Scaffold29, whole genome
            shotgun sequence.
ACCESSION   NZ_SWMS01000029
VERSION     NZ_SWMS01000029.1
KEYWORDS    WGS; RefSeq.
SOURCE      Prauserella endophytica
  ORGANISM  Prauserella endophytica
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Prauserella; Prauserella
            coralliicola group.
REFERENCE   1  (bases 1 to 79922)
  AUTHORS   Liu,J.M., Habden,X., Guo,L., Tuo,L., Jiang,Z.K., Liu,S.W., Liu,X.F.,
            Chen,L., Li,R.F., Zhang,Y.Q. and Sun,C.H.
  TITLE     Prauserella endophytica sp. nov., an endophytic actinobacterium
            isolated from Tamarix taklamakanensis
  JOURNAL   Antonie Van Leeuwenhoek 107 (6), 1401-1409 (2015)
   PUBMED   25832628
REFERENCE   2  (bases 1 to 79922)
  AUTHORS   Li,Q.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-APR-2019) Yunnan Institute of Microbiology, Yunnan
            University, No. 2 Cuihu North Rd, Kunming, Yunnan 650091, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 10.16x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_005146945.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 16:32:08
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,852
            CDSs (total)                      :: 7,795
            Genes (coding)                    :: 7,703
            CDSs (with protein)               :: 7,703
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 34 of 92
            Pseudo Genes (incomplete)         :: 69 of 92
            Pseudo Genes (internal stop)      :: 2 of 92
            Pseudo Genes (multiple problems)  :: 13 of 92
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 18:09:25
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 58932
            Orig. end                         :: 79922
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            SWMS01000029.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20990
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="redox-cofactor"
                     /region_number="1"
                     /rules="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /tool="antismash"
     cand_cluster    1..20990
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(PF04055 and (TIGR04085 or SPASM))
                     and (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /kind="single"
                     /product="redox-cofactor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20990
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:12145](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12145)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
     gene            630..1439
                     /locus_tag="FCN18_RS33070"
                     /old_locus_tag="FCN18_33065"
     CDS             630..1439
                     /NRPS_PKS="Domain: ECH (17-259). E-value: 3.8e-55. Score:
                     178.8. Matches aSDomain:
                     nrpspksdomains_FCN18_RS33070_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012596.5"
                     /locus_tag="FCN18_RS33070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_33065"
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="WP_112273603.1"
                     /transl_table=11
                     /translation="MAVIDYSVYENILASRAGSVLTLTLNRPERFNAVNHELHEELSRI
                     FTDVAVDDETSVVVLTGAGRAFCAGGDLKAFAADAEEQGRTGHYLDMGSAKRIIFSLLD
                     LEKPIIAKVNGHALGLGATLALFCDIVYMADDARIGDPHVSAGVVAGDGGAIIWPQLVG
                     YARAKEFLLTGDQLSATRAADMGLVNHAVPAEDLDRAVDELAARLASGAQEAIRWSKVS
                     VNVGLKQLAHSILDTSIAYETLTMRSPAHAEAIDAFSNGRKPDFTSL"
     aSDomain        681..1406
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FCN18_RS33070_ECH.1"
                     /evalue="3.80E-55"
                     /label="FCN18_RS33070_ECH.1"
                     /locus_tag="FCN18_RS33070"
                     /protein_end="259"
                     /protein_start="17"
                     /score="178.8"
                     /tool="antismash"
                     /translation="GSVLTLTLNRPERFNAVNHELHEELSRIFTDVAVDDETSVVVLTG
                     AGRAFCAGGDLKAFAADAEEQGRTGHYLDMGSAKRIIFSLLDLEKPIIAKVNGHALGLG
                     ATLALFCDIVYMADDARIGDPHVSAGVVAGDGGAIIWPQLVGYARAKEFLLTGDQLSAT
                     RAADMGLVNHAVPAEDLDRAVDELAARLASGAQEAIRWSKVSVNVGLKQLAHSILDTSI
                     AYETLTMRSPAHAEAIDAFS"
     misc_feature    complement(1762..1779)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.84"
                     /tool="antismash"
     gene            1797..2522
                     /locus_tag="FCN18_RS33075"
                     /old_locus_tag="FCN18_33070"
     CDS             1797..2522
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005163716.1"
                     /locus_tag="FCN18_RS33075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_33070"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_137096958.1"
                     /transl_table=11
                     /translation="MRIDVDGVSKRFGHVRAVEELSFTVRPGAITGFLGPNGSGKSTTM
                     RIMLGLVSPDTGSATIGGRRYAELDHPTRTVGAVLDTMRAHPAMTCLDHLRLHARLSGH
                     PVRQLDAAAEQTGVATFAARRVRTLSTGMRQRLALATALLGDPGVLVLDEPANGLDPQG
                     LAWLRDLLTRLAAEGRTVLVSSHVLAELEVMADDVVIIAEGRLVTAGPLREVLAAAGED
                     GAPARSLEQVFLSLTNGAA"
     gene            2522..3313
                     /locus_tag="FCN18_RS33080"
                     /old_locus_tag="FCN18_33075"
     CDS             2522..3313
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016697888.1"
                     /locus_tag="FCN18_RS33080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_33075"
                     /product="ABC transporter permease"
                     /protein_id="WP_112273599.1"
                     /transl_table=11
                     /translation="MRLIAAELFRFRANRLWYWSLLAALVLGCGFTALFAVIGPENFDP
                     PMPALTTHEGVRMMLGLATTTLFVPALIGAIAVTGEFRHQTFGHTVLAEPRRGRVLAAK
                     LAALAIVGAGYALVVTAGTLAALYGTTAVAGTRLGAPPGEVLTTLFGAATAMVVYSVVG
                     GGIGALVRHQLAAVGAVLGYFSLGEIVVLVLPGVNAVYPYLPGGASAALTDFGYLTEAV
                     AADTGTVTTLLPPLAGLAVLLGYAVTVAALATVSSLRRDIP"
     gene            complement(3327..3875)
                     /locus_tag="FCN18_RS33085"
                     /old_locus_tag="FCN18_33080"
     CDS             complement(3327..3875)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_Docking_Cterm (2-34). E-value:
                     0.0017. Score: 11.2. Matches aSDomain:
                     nrpspksdomains_FCN18_RS33085_PKS_Docking_Cterm.1"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012655.5"
                     /locus_tag="FCN18_RS33085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_33080"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_113642809.1"
                     /transl_table=11
                     /translation="MTRTKPAEQRRSELLDAAEALLQRDGADAFTVDDVTSGAGVAKGT
                     FYLHFSNKSELLQALRERFVRRFADAQLAAARQASGVESVERWMRAGVTEYLRELSLHD
                     LLFHPTSGIERDAPNAAVDALAELLGRLDPPVPDPPVTAVILYSAMHGATDHVVHTPAD
                     EQRVLDGLTRLCRALIPAR"
     aSDomain        complement(3774..3869)
                     /aSDomain="PKS_Docking_Cterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FCN18_RS33085_PKS_Docking_Cterm.
                     1"
                     /evalue="1.70E-03"
                     /label="FCN18_RS33085_PKS_Docking_Cterm.1"
                     /locus_tag="FCN18_RS33085"
                     /protein_end="34"
                     /protein_start="2"
                     /score="11.2"
                     /tool="antismash"
                     /translation="RTKPAEQRRSELLDAAEALLQRDGADAFTVDD"
     misc_feature    complement(3953..3971)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 24.03"
                     /tool="antismash"
     gene            4041..5846
                     /locus_tag="FCN18_RS33090"
                     /old_locus_tag="FCN18_33085"
     CDS             4041..5846
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016700272.1"
                     /locus_tag="FCN18_RS33090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_33085"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_112273597.1"
                     /transl_table=11
                     /translation="MTITDSRPTTPKPEPATERPSAAAAGLARTGALARLLAPVRAHLV
                     GCAVLSALATAAGFVPYVAVAEIATLALAGGYSPSAIWGWVALGAAGAGLRLVLVFASS
                     RLGHYADARTLHDLRVRMVRHLGSLPLGWFRANGSASVKKRMTNDLEEMHQLIAHALGE
                     LVGATTAVALGLFYLASVNPVMTLVTAGSLALLGISYRIAMRSMTLHMNRLLAAESRIS
                     AASVEYADGIGVVKAFGTGGRVLERFGEAVREQAAALAAWADETRYSTAASRLLASEMA
                     LLGILGAAGLALVHAGQLSMTELLPFLVVGIGLPTSINPAIHGTQTLRKGRVCAQNIEA
                     LLGMEPLPEPSRPLSPEGSRLELDRVTFSYDGHTDAVRDVSAVCEPGTITALVGPSGAG
                     KSTMASLIPRFYDVTGGAIRLGGVDVRDMAASTLLSSMSLVFQDVMLLRDTVTENLRIG
                     NPGATDDEVRAAARAAQIHDVIERLPDGYNTVLGDGGGLSGGERQRLTIARAILSRAPI
                     VVLDEATASLDPDSETAVHSALSRLIAGKTVIVIAHRLHTIAGADQILVLEDGRLVERG
                     THHDLIEAGGRYARMWAAQQNGDPA"
     gene            5843..6109
                     /locus_tag="FCN18_RS33095"
                     /old_locus_tag="FCN18_33090"
     CDS             5843..6109
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FCN18_RS33095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FCN18_33090"
                     /product="hypothetical protein"
                     /protein_id="WP_113642808.1"
                     /transl_table=11
                     /translation="MTYHRPFAILPRLPGASLAALQCTDTAPESVLDRLNSGLTVATFV
                     CGRGDTVVVLREGRVVETGSAADLVAAGGVYAGLRRAWAGVTA"
     gene            6106..7866
                     /locus_tag="FCN18_RS33100"
                     /old_locus_tag="FCN18_33095"
     CDS             6106..7866
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005151692.1"
                     /locus_tag="FCN18_RS33100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_33095"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_137096959.1"
                     /transl_table=11
                     /translation="MIRHLHRLVPQPGLLLRLGALTAVQAVLQGLLLGSLIPILRALLR
                     PEPDFGAAAPWLVAAAAGLVVYGVLTVIATPVGFAASSDLAGQLRRRLIDHSASLPLGW
                     FTPEHKARLARATTADAANIGNLAVSIGGPAITATLTPLTIIGVTVAVDWRVALLFAVI
                     MPVALLALRRAGRIASIADVELEQAAADIAGRAIELGQAQPVLRAAGQSSTGTARMREA
                     LDEHRTVYRRGLRRSMAPDLTYTGVIMAGFVAILVVSALLLLDGTLGVAEVVALLVLAV
                     RFLEPLGNLVELIGALHAMDNAVGRVRALLATPPLPEADRPVTELPGTSVELSGVTFTY
                     PGGSTPALAGVSFTCAPGSTTAIVGPSGSGKTTVTRLIARFFDPQEGSIRIGGVDVREL
                     DQRTLLDSIAVVFQDVYLFDDTIEENLRLAKPDATDAELAEAARAARLDEVVERLPEGW
                     HTRVGEGGSRLSGGERQRVSIARAFLKQARIVLIDEAASALDPENERAVSQAIARLAAD
                     RGRTVLVIAHRPATLDAADHVLTLHNGHVAEAGTPAGLRATGGLFARLYDQYDHARSWR
                     LDRESATEVG"
     gene            7869..8840
                     /locus_tag="FCN18_RS33105"
                     /old_locus_tag="FCN18_33100"
     CDS             7869..8840
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1033: iron
                     compound ABC transporter, periplasmic"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF013648.5"
                     /locus_tag="FCN18_RS33105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_33100"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_158303219.1"
                     /transl_table=11
                     /translation="MRTAFRGLAAVTLLAVTACGPGDAAPRQPGGPEVTVRSAVGEVTL
                     PVTDTGIWALDEASALHLLSLGVRPTHAARNAYSGDEIVTASYALLEEAGVELVPPQRP
                     ELVASAEPALIVGVDFPAHHEQRAQLEQIAPVLLTDDNLPWQEQLALLGAVTGHGEQAD
                     ALTGRLMAQVRDTAGRIAASEHAGASVSVLSDCGDQACVYGSGRALGSLLAQLGFTRPQ
                     AQRDKGGEWGYDMVSRERLAEHTADIVLSLVGSIGGDLVAGDSPLLDTSRAVTAPVDFG
                     AWYGSGTLNLVWMLHDLEAILFGDGKTATAAEAGRLWSRLDG"
     misc_feature    complement(9215..9229)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.31"
                     /tool="antismash"
     misc_feature    9216..9230
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.51"
                     /tool="antismash"
     misc_feature    complement(9220..9234)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 20.17"
                     /tool="antismash"
     misc_feature    complement(9414..9430)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 17.4"
                     /tool="antismash"
     gene            9502..10041
                     /locus_tag="FCN18_RS33110"
                     /old_locus_tag="FCN18_33105"
     CDS             9502..10041
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018333391.1"
                     /locus_tag="FCN18_RS33110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_33105"
                     /product="manganese efflux pump"
                     /protein_id="WP_113642805.1"
                     /transl_table=11
                     /translation="MIWEVLVLGFVLSLDNFRVSIALGTVPFGLKRAVQVALTFGLWDA
                     IMPLVGLLIGNKIGESIGDVAEWVGAAALGAYGLYLVISALRNPEPDELDHPWALFGIP
                     FMLSLDNLFAGASLGILGFSPWFSAAVFGIMTAVLSLVGLRLGQAAARLIRIRSDLVSG
                     VTLIIAAVALPLVFGG"
     misc_feature    9510..9524
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.27"
                     /tool="antismash"
     gene            complement(10001..11125)
                     /gene="pqqE"
                     /locus_tag="FCN18_RS33115"
                     /old_locus_tag="FCN18_33110"
     CDS             complement(10001..11125)
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_process="GO:0018149 - peptide cross-linking [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: SPASM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010228268.1"
                     /locus_tag="FCN18_RS33115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_33110"
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqE"
                     /protein_id="WP_137096960.1"
                     /sec_met_domain="PTHR43273 (E-value: 6e-33, bitscore:
                     106.6, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 4.7e-25, bitscore: 81.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 9.2e-11, bitscore: 34.6,
                     seeds: 166, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 1.2e-10, bitscore:
                     34.1, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDSPFGLLAELTYRCPLACAYCSNPLNMADYSAELATDEWRRVLA
                     EAGDLGVLQCHLSGGEPLLRRDLAEIVAEAHDLGLYTNLVTSAVGLSRPRAEQLRAAGL
                     DHVQISIQADEPAISDRIAGTPSWRRKIEAMGVVKELGWPLTVNVVLHRNNIDRVAGVL
                     ELAEEVGADRVELANTQYYGWALRNRDALLPSRAQLRAAEVVVRAARERLRNRMDVIYV
                     LPDYYSRYPKPCMGGWASRQLTVTPNGDVLPCPAAQSLPLPRASVREDTLERIWAESPV
                     MTAFRGTDWMPNPCRSCDRRELDFGGCRCQAFQLTGDAARTDPVCHLSPDHGLVAKAVE
                     AANADSRADALPLIPRPHGVRPSPRTPTAAPRRR"
     gene            complement(11118..11426)
                     /gene="pqqD"
                     /locus_tag="FCN18_RS33120"
                     /old_locus_tag="FCN18_33115"
     CDS             complement(11118..11426)
                     /GO_function="GO:0048038 - quinone binding [Evidence IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010696864.1"
                     /locus_tag="FCN18_RS33120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_33115"
                     /product="pyrroloquinoline quinone biosynthesis peptide
                     chaperone PqqD"
                     /protein_id="WP_112274796.1"
                     /sec_met_domain="PqqD_RRE (E-value: 1.8e-20, bitscore:
                     65.0, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 2.3e-13, bitscore: 42.7,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYPSTAGTDPGGGLSTSDTPRLARHVRLTFCRTRQRPILQLPETV
                     VVLNGSGADILELCDGRHTVAEIVAELGARYQTVPGDEVRQFLTRLVARRCVELADG"
     aSDomain        complement(11130..11384)
                     /aSDomain="PqqD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing protein in a pyrroloquinoline
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_FCN18_RS33120_PqqD_RRE.1"
                     /evalue="6.10E-21"
                     /identifier="RREFam006.1"
                     /label="FCN18_RS33120"
                     /locus_tag="FCN18_RS33120"
                     /protein_end="99"
                     /protein_start="14"
                     /score="65.0"
                     /tool="antismash"
                     /translation="STSDTPRLARHVRLTFCRTRQRPILQLPETVVVLNGSGADILELC
                     DGRHTVAEIVAELGARYQTVPGDEVRQFLTRLVARRCVEL"
     gene            complement(11432..12145)
                     /gene="pqqC"
                     /locus_tag="FCN18_RS33125"
                     /old_locus_tag="FCN18_33120"
     CDS             complement(11432..12145)
                     /EC_number="1.3.3.11"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR02111"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020670612.1"
                     /locus_tag="FCN18_RS33125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_33120"
                     /product="pyrroloquinoline-quinone synthase PqqC"
                     /protein_id="WP_137096961.1"
                     /sec_met_domain="TIGR02111 (E-value: 5.1e-99, bitscore:
                     322.8, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTTTGTTATASTGADGFVGTLRAHSRRYHDQHPFHVRMNTGRLS
                     RGQIQGWVANRFYYQENIPRKDAAILSNCPDPEVRRRWLRRIVDHDGTATGEGGIEAWL
                     RLGEAAGLTREEVRDHRHLVPGVRFAVDVYVNFARTRPWVEAVASSLTELFAPDLMAQR
                     LAAFERWYSWIDPEGLAYFRARLEQAPRDCEHALEVVTASCRSAESQARAVDALSFKCD
                     VLWSLMDAIDQAYPE"
     gene            complement(12150..12626)
                     /locus_tag="FCN18_RS33130"
                     /old_locus_tag="FCN18_33125"
     CDS             complement(12150..12626)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024118.5"
                     /locus_tag="FCN18_RS33130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_33125"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_228714251.1"
                     /transl_table=11
                     /translation="MAPDQRAVAPGAEMAFADGLTCRAFDVPSVVHGRVAGHRLTDGRG
                     GGTLVYLPVVQAVTPVLRMEIQGCQCLLIDGSCWRDDELVRLGLAGKTAREMGHLPIDG
                     RDGSLAQLPSLAVGRTIFVHMNNTNPILLEDSPERRVVEDSGMQVAMDGLEVEV"
     gene            complement(12860..12955)
                     /gene="pqqA"
                     /locus_tag="FCN18_RS33135"
                     /old_locus_tag="FCN18_33130"
     CDS             complement(12860..12955)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013672938.1"
                     /locus_tag="FCN18_RS33135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_33130"
                     /product="pyrroloquinoline quinone precursor peptide PqqA"
                     /protein_id="WP_112273585.1"
                     /transl_table=11
                     /translation="MESELAVWETPEFDEIGVAPEVTMYVAQLED"
     gene            complement(13005..14705)
                     /locus_tag="FCN18_RS33140"
                     /old_locus_tag="FCN18_33135"
     CDS             complement(13005..14705)
                     /EC_number="1.1.2.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005509 - calcium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009942739.1"
                     /locus_tag="FCN18_RS33140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_33135"
                     /product="PQQ-dependent dehydrogenase, methanol/ethanol
                     family"
                     /protein_id="WP_137096962.1"
                     /transl_table=11
                     /translation="MTVEYVDAGEAIDQGNLSGKVPGGDVAPPVVRGVNYERILNARSE
                     PQNWLTYYGAYNGQRYSPLDQINTENVKRIGPAWVFQAGTTGMIAGASTYSFEAAPIVV
                     DGIMFLAGWDGWVWALDAKTGVEIWRYKHAVPFDVSLCCGNVNRGVAVAAGKVFVVTAN
                     AHVLALDATTGKRVWDKTYGDVRAGESATVAPLVVKDKVIVGSSGGEFGVRGHLDAFNL
                     ETGEYQWRCYMVPKPGEPGADTWPADGEAWARGGANCWITATFDPETNLLYVGTGNPAP
                     DFDGGVREGDNLYTDSIVAVDVDGGQIRWHYQCTPHDVWDYDSIGECILFESDGRKLLG
                     HFDKNGYFFVLDRTNGALVQITPFVDRITWGAITRDGQVTAKVYPDEEGVPVHFYPGPA
                     GAKEWTHAAYSPKTGLFYVPVQDVGATATRRRREFRESIPYWGAGVQVDIEEMTGSISA
                     FDAAGDERWRWRNELPMCASVLATGGDLVFAGEPTGEFNALDARTGELLWQFQCGSGHH
                     SNPTTYMVDGRQYVAVPVGWGAWSEGFLPGMLGAGHGSALITFALPETS"
     gene            complement(14721..15182)
                     /locus_tag="FCN18_RS33145"
                     /old_locus_tag="FCN18_33140"
     CDS             complement(14721..15182)
                     /GO_process="GO:1901661 - quinone metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010242305.1"
                     /locus_tag="FCN18_RS33145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_33140"
                     /product="MSMEG_3727 family PQQ-associated protein"
                     /protein_id="WP_112273581.1"
                     /transl_table=11
                     /translation="MTTAQDRAGLLDELGLDAQNKAALGQVLGTGTIGQATERADGRME
                     ATIRIRPDEISWDPSILVMPHGGDIELELINDDLNTHCALLPSNGDRKFIWLVNHSRGR
                     AKLNLDGPGYYWFSSPTGNDEGRGLTGAIVVLGDVPPEARLDRPDQPRP"
     misc_feature    complement(15238..15248)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     misc_feature    complement(15313..15328)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.19"
                     /tool="antismash"
     gene            complement(15513..17762)
                     /gene="katG"
                     /locus_tag="FCN18_RS33150"
                     /old_locus_tag="FCN18_33145"
     CDS             complement(15513..17762)
                     /EC_number="1.11.1.21"
                     /GO_function="GO:0004096 - catalase activity [Evidence
                     IEA]"
                     /GO_function="GO:0004601 - peroxidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /GO_process="GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="katG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009943439.1"
                     /locus_tag="FCN18_RS33150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_33145"
                     /product="catalase/peroxidase HPI"
                     /protein_id="WP_137096963.1"
                     /transl_table=11
                     /translation="MSDSPDASDSTVGESNSGNAAGLGLSVPAGRRGHPTGGASSRDWW
                     PNRLNLTILRKHPAAGDPMGEDFDYAAEFRTLDLDALARDVDEVLTTSQEWWPADFGHY
                     GPLVIRMVWHSAGTYRVDDGRGGAGAGMQRFAPLNSWPDNRNLDKARRLLWPVKKKYGR
                     KISWADLMIFAGNRALETMGFKTFGFAGGRTDVWEPGEDVYWGHERAWLGDERHSGVRE
                     LENPLAAVQMGLIYVNPEGPNTVPDPLAAARDIRETFRRMGMNDEETVALIAGGHTFGK
                     THGAADPERHLGPEPEGAPIEEQGLGWKSSYGTGKGTDTISSGLEGTWTPTPTRWDNSF
                     FETLFGYEWDLELSPAGLWQWIPRDGGGAGTVPDAHDPSKTHAPTILTTDLALRFDPVY
                     EPISRRFLENPDLLADAFARVWFKLTHLDMGPIQRYLGALVPKERLLWQDPIPAVDHEL
                     VDDTDVGALKARILDSGLPAAQLVSTAWASASTFRVSDKRGGANGARIRLEPQRRWEVN
                     EPDTLAQVLRTLEKIQESFNGAQTGGKKISLADVIVLGGCAAVEQAATAAGYHVEVPFT
                     PGRMDASQEWTDVESFAPLEPTADGFRNYRAKGDRLPAEHRLVDRANLLTLSAPEMTVL
                     VGGLRVLGANYGRSRLGVLTSTPGLLTNDFFVNLLDMGIEWSPVAEDAETFEGRDRRIG
                     EVKWTASRVDLVFGSNSELRALAEVYASDDAEEKFVHDFVAAWDKVMNLDRYDMA"
     misc_feature    complement(15783..15785)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(17800..19281)
                     /locus_tag="FCN18_RS33155"
                     /old_locus_tag="FCN18_33150"
     CDS             complement(17800..19281)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017983444.1"
                     /locus_tag="FCN18_RS33155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_33150"
                     /product="DNA-binding protein"
                     /protein_id="WP_228714252.1"
                     /transl_table=11
                     /translation="MGPAATSGDQRGPRARRRALGMNQGRFSTMRDAHRLEPVAANPGS
                     GTVLAAWERFVQGEDQVPAVRPLVAISWHRCREQYRVDPHLTAAPIAVAEPDRTPEHDV
                     VFAELGFRAASVAHEMGNLGGVVTVTDATGRILAEWGDQATLARATDSNLAPWFCWSEC
                     AAGTNGMGTALEAHGPISIRGPEHWCQAFHNWVCAGVAVRDVVTREPIAVLNISCWRSQ
                     LPAAAGSWLANAATLTQCTLKKHARDSGAELVAAFTQARAHSTAMLAALDTAGKVVIAD
                     DMASVLMGVPASTPAVDPTLRWNPGLPELVGAVRYAVRQAAHNPDWVGSTQIFTHLADE
                     PTSISIRPVFSSGRLIGNLVSFGASDGAPLPQAEASASPRAQPRRLVATRDNRMVLLRL
                     PEVAFAESEGNDVLLATDQGRLRAASPGLDKLDGELADAGFLRVHRRYVVNLSRIREVE
                     RGRKGELSLVMDDRTNTMVPVSRRNAPAVRRALEI"
     gene            complement(19577..20065)
                     /locus_tag="FCN18_RS33160"
                     /old_locus_tag="FCN18_33155"
     CDS             complement(19577..20065)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009942744.1"
                     /locus_tag="FCN18_RS33160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_33155"
                     /product="YkvA family protein"
                     /protein_id="WP_137096964.1"
                     /transl_table=11
                     /translation="MTGSFWWDLLISVVATLVLAWLALGIALMVLRPRGGLLREAVRVL
                     PDVLRLVRRLAADTTLPRGVRIRLGLLLAYLAIPIDLVPDFIPVLGYADDAIIATAVLR
                     SMVRRAGLDPVRAHWPGTDDGFTALTRLLGLTTRTHPETTEQSEHCPPACRQHQRRSR"
     gene            complement(20062..20628)
                     /locus_tag="FCN18_RS33165"
                     /old_locus_tag="FCN18_33160"
     CDS             complement(20062..20628)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007030338.1"
                     /locus_tag="FCN18_RS33165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_33160"
                     /product="Chromate resistance protein ChrB"
                     /protein_id="WP_113642799.1"
                     /transl_table=11
                     /translation="MISISTAGAAGTLRVRVWRKLRSLGALYLQQSVCLLPADDEVVRQ
                     VRRLVDRVRHQGGTARVLRMRFTEPAEEQAVVAEMNAARDAEYAEVLDRLPALRQELAQ
                     ERARGRATYAEVEESEADLARFRTWLTKIAARDYFDAPGGRAARDAVDEAAADLAAFEQ
                     AAFQAEAPDPVARRSPRRLRAVADS"
     misc_feature    complement(20617..20632)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.68"
                     /tool="antismash"
ORIGIN
        1 cgggtcagcg gcccgctcac cgttccgatg tgcgcgccca tgagcgatgg ggcggccgcg
       61 gtgcttgtgg ccgtaccgga actggcccgc cgttggggcg cagatggtgt tcgcctgcgc
      121 gctgtggtgg tgggggccgg gcgccgtgga gtgcttggag aactgctccc cgccgccgcg
      181 ctccgtgcgt tcgagcaagc cggggtcggc cccgaggaca tcgacctcgt cgagtgccat
      241 gacgcggccg cgccggcgga gctgatcgtg ctcgaggaac tcgggctttg tgcgcccggc
      301 gaggccgtgg caaaactacg cgacggggcg acccggatcg gcggggagct cccggtcaat
      361 ccgagcggag gcctgcagag ccgaggacat ccgctcgggg ccaccggtct cgcgcaggtc
      421 gtcgagctgg cggaccagct ccgtggccga gccggggctc ggcaggctgg tgagccccag
      481 gcgggtctcg ccgagaacgc cgggggatac ctcggacccg acgccgccgc ggcaacggtg
      541 acgatcctga gccggtgaaa ccggtagggg gcgcccgtcc ggccgcaacg gcggcacggg
      601 ccaccgaccg cgaaacgaag gagccatgaa tggccgtgat cgactacagc gtgtacgaga
      661 acatcctcgc cagtcgcgct ggttccgtgc tgactctgac gttgaaccgc ccggagcggt
      721 tcaacgcggt caaccacgag ctccacgagg aactgagccg catcttcacc gacgtcgccg
      781 ttgacgacga gacgtccgtg gtcgtcctga ccggagcggg gcgcgccttc tgcgcgggcg
      841 gcgacctgaa ggccttcgcc gcggacgccg aggagcaggg ccgcacggga cactacctcg
      901 atatgggatc ggccaagcgg atcatcttct ccctgctcga tctggagaag ccgatcatcg
      961 cgaaggtcaa cggtcacgcg ctgggtctcg gtgcgacgtt ggccctgttc tgcgacatcg
     1021 tctacatggc tgatgacgcc cggatcggcg atccgcacgt atccgcgggt gtcgtcgccg
     1081 gcgacggggg agcgatcatc tggccacagc tcgtcggata cgcgcgagcc aaggaattcc
     1141 tgctgaccgg cgaccagctc tcggcaacgc gtgccgcgga catgggactc gtgaaccacg
     1201 cggtgccggc cgaggacttg gaccgggctg tcgatgaact ggccgcgcgc cttgcttcgg
     1261 gggcacagga ggccatccgg tggagcaagg tgtcggtgaa tgtcggcctg aagcagctcg
     1321 cccattcgat cctggacacg tcgatcgcct acgagacact cacgatgcgc agccccgcgc
     1381 acgccgaggc catcgatgcc ttctccaacg gtcgaaagcc ggacttcacg tcactctgat
     1441 cactgtcgag gggcggtccg cgcaccgacc gcgacggccg ggtccgccac gttggctgga
     1501 ccgtcctatc gggactgttc ggcgagggtg accatggcgg gcgtgaccgg actcgccgac
     1561 gggagccggt ggcaccatcg gcccccgcgg gcctgtcgcg ccggaagcgc cgcagccgcc
     1621 aggaagggac ccgcggcggt gttcctcgcg gctcgtcgcg gctcagccgc tcagccagca
     1681 cgcctgcgcc gccgcgcggc tccgggagcg gcctcgcgat ggtgggcccc gccctgctga
     1741 ttgttcccaa ggttggtaac attaccaaga ctggaacaag cagggggtgg tcgcgcatgc
     1801 ggatcgacgt cgatggggtg agcaaacgat tcgggcacgt ccgcgctgtg gaggagcttt
     1861 ccttcaccgt gaggccgggc gcgatcacgg gtttcctggg ccccaacggt tccgggaagt
     1921 ccaccactat gcggatcatg ctcggactcg tctccccgga cacgggatcg gccacgatcg
     1981 gcggacgccg ctacgccgag ctcgaccatc cgactcgcac cgtcggcgcg gtgttggaca
     2041 cgatgcgggc ccatcccgcc atgacctgtc tggaccacct gcggctgcac gcgcggctga
     2101 gtggccaccc ggtccggcag ctggacgcgg cggccgagca gaccggcgtc gccaccttcg
     2161 cggcgcgccg ggtgcgaacg ctgtcgacgg ggatgcgcca gcgcctcgcg ctggccaccg
     2221 cactgctggg cgatcccggt gtgctcgtac tcgacgaacc ggcgaacggg ctcgaccccc
     2281 agggcctggc ctggctacgg gacctgctca cccggctcgc cgccgaggga cgcacggtgc
     2341 tggtgtcgag tcacgtgctc gccgagctcg aggtcatggc cgacgacgtg gtgatcatcg
     2401 ccgagggcag gctcgtcacg gcgggtccgc tgcgcgaggt gctcgccgcg gccggtgagg
     2461 atggcgctcc ggcgcggtcg ctcgagcagg tcttcctgag cctcacgaac ggagccgcct
     2521 gatgcgcctg atcgccgccg aactgttccg gttccgcgcg aaccggttgt ggtactggtc
     2581 gctgctcgcc gcgctcgtcc tcggctgcgg gttcaccgcg ctgttcgccg tgatcgggcc
     2641 ggagaacttc gatccgccga tgcccgcgct caccacgcac gagggcgtgc ggatgatgct
     2701 cgggctcgcc accacgaccc tgttcgttcc ggcactcatc ggcgcgatcg ccgtgacggg
     2761 cgagttccgc catcagacgt tcggccacac ggtgctcgcc gaaccccgcc ggggccgggt
     2821 gctggccgcc aagctggccg cgctcgccat cgtcggcgcc gggtacgcgc tggtggttac
     2881 cgcgggcacg ctcgcggcgc tctacggcac caccgctgtc gcgggtaccc ggctcggcgc
     2941 gccgccgggg gaggtcctca ccacgctgtt cggtgccgcg accgcgatgg tcgtgtactc
     3001 ggtggtcgga gggggcatcg gcgcactcgt gcggcaccag ctcgccgcgg tgggcgcggt
     3061 gctcggctac ttctcgctcg gggagatcgt cgtgctggtg ctccccggcg tcaacgccgt
     3121 gtacccgtat ctgcccggtg gagcgagcgc ggcgctgacg gacttcggtt acctgaccga
     3181 ggccgtcgcc gccgacaccg gaacggtgac cacgctgctg ccgccgctcg ccggactcgc
     3241 ggtgctcctc ggttacgccg tgaccgtcgc cgcgctcgcc acggtgagtt ccctgcggcg
     3301 cgacatcccc tgagaccggt tgacggtcag cgcgcgggaa tcagggcgcg gcagagccgg
     3361 gtgagcccgt cgagcacgcg ctgttcgtcc gctggcgtat ggaccacgtg gtccgtggcg
     3421 ccgtgcatgg ccgagtagag gatcaccgcg gtcaccggcg gatcgggcac gggtgggtcg
     3481 agccggccga gcagctcggc cagcgcgtcc accgcggcat tgggcgcgtc ccgctcgatc
     3541 ccgctcgtcg ggtggaacag caggtcgtgc aggctcagct cccgcaggta ctcggtgacg
     3601 cccgcgcgca tccaccgctc gacgctctcg accccgctcg cctgccgcgc ggcggccagc
     3661 tgcgcgtcgg cgaagcggcg cacgaagcgt tcgcgcagtg cctgaagcag ctcggatttg
     3721 ttgctgaagt gcagatagaa cgtgcccttg gcgacaccgg cgcccgaggt gacgtcgtcg
     3781 acggtgaacg cgtcggcgcc atcgcgctgc agcagggcct ccgccgcgtc gagcagctca
     3841 ctgcgccgct gctcggcagg tttcgttcgc gtcaccgcac tcccttcgac cgaggcacag
     3901 gctacccgcg gccggacagc cgcgcgccgg ccgcgcgccg ccccggcctt gcatagggca
     3961 gccttacctc atacagtgac tgactgacgg tcagtcgact gtcagtctcg ctcattgcga
     4021 ccacgaaccc gcggaggacc atgaccatca ccgactcccg gcccactacc cccaaaccgg
     4081 agccggcgac cgagagaccg tcggccgcgg ccgcgggcct ggcgcgcacg ggcgcgctcg
     4141 cccggctgct tgcgcccgtg cgagcccacc tggtggggtg cgccgtgctc tccgcgctgg
     4201 cgaccgccgc cggtttcgtg ccctacgtcg ccgtcgccga gatcgccacg ctggccctcg
     4261 cgggcggcta ctccccgagc gcgatctggg gctgggtggc cctgggcgcc gccggcgcgg
     4321 gccttcgtct ggtgctcgtg ttcgccagct cgcggctcgg gcactacgcc gacgctcgca
     4381 ccctgcacga tctgcgcgtg cggatggtgc gccacctcgg ctcgctgccc ctcggctggt
     4441 tccgcgccaa cggctcggcc tcggtcaaga aacggatgac caacgacctc gaggagatgc
     4501 accagctcat cgcgcacgcg ctgggcgaac tggtcggcgc caccaccgcg gtcgcgctcg
     4561 gactgttcta cctcgcctcc gtgaacccgg tgatgacact ggtgaccgcg ggatcgctcg
     4621 cgctgctcgg tatcagctac cggatcgcga tgcggtcgat gacgctgcac atgaaccggc
     4681 tcctcgcggc cgagtcgaga atcagcgccg cgagtgtcga gtacgccgac ggtatcggcg
     4741 tggtcaaggc gttcggcacc ggaggacgtg tgctggagcg cttcggcgag gccgtccgcg
     4801 aacaggcggc ggcgctggcc gcgtgggcgg acgagacccg ctacagcacg gcggcctcgc
     4861 gcctgctggc ctcggagatg gccctgctcg gcattctcgg cgctgcggga ttggcgctcg
     4921 tgcacgccgg gcagctgtcg atgaccgagc tgctgccgtt tctcgtcgtc gggatcggcc
     4981 tgccgacgtc gatcaacccg gcaatccacg gcacgcagac actgcgcaag ggccgggtct
     5041 gcgcgcagaa catcgaggca ctgctcggga tggagccact gcccgagccg tcccggccac
     5101 tcagcccgga gggctcccga ctcgagctgg accgcgtcac gttctcctac gacggccaca
     5161 ccgacgccgt ccgcgacgtg agcgcggtgt gcgagcccgg aaccatcacc gcgctggtgg
     5221 gcccctccgg cgcgggaaag tccacgatgg ccagcctgat cccgcgcttc tacgacgtca
     5281 ccggcggcgc catccgcctc ggcggcgtgg acgtgcggga catggcggcg tccacgctgc
     5341 tgtcgtcgat gtcgctggtg ttccaggacg tcatgctgct gcgtgacacc gtgaccgaga
     5401 acctccgcat cggcaacccc ggcgcgactg acgacgaggt gcgcgccgcc gcacgggcgg
     5461 cgcagatcca cgatgtcatc gagaggctgc cggacggcta caacaccgtg ctcggcgacg
     5521 gaggcggcct ttccggcggc gagcgccagc ggctcaccat cgcgagggcg atcctgtcgc
     5581 gagcgccgat cgtcgtgctt gacgaggcga cggcctcgct cgacccggac agcgagacag
     5641 ccgtccacag tgcactgtcg cgcttgatcg cgggcaagac ggtgatcgtg atcgcccacc
     5701 gcctgcacac cattgccgga gcagaccaga tcctcgtcct cgaggacgga cggctggtcg
     5761 aacgcggcac ccaccacgac ctcatcgaag ccggcggccg ctacgcccgc atgtgggccg
     5821 cccagcagaa cggagacccg gcatgaccta ccatcggcct ttcgcgattc tcccgcgcct
     5881 tcccggcgca tcgctcgccg cgctgcagtg cacggacacc gcaccggagt cggtgctgga
     5941 ccggctcaac tccgggctca ccgtcgcgac cttcgtctgc gggcgcggcg acacggtcgt
     6001 cgtgctgcgg gaggggcgcg tggtcgagac cggctccgcg gccgacctcg tcgccgccgg
     6061 cggcgtctac gccggcctgc ggcgcgcctg ggcgggggtc accgcgtgat ccggcacctc
     6121 caccgcctcg tcccgcagcc cgggctgctg ctgcgcctcg gcgccctcac cgcggtacaa
     6181 gccgtgctgc agggcctgct gctcggctcc ctcatcccga tcctgcgtgc cctgctgcgg
     6241 cccgagcccg acttcggtgc ggcggcgccg tggctggtcg ccgccgcggc cgggctcgtg
     6301 gtctacggcg tgctgacggt gatcgccacc ccggtcgggt tcgccgccag ctccgatctc
     6361 gccgggcagc tgcggcgcag gctgatcgac cactcggcgt ccctgccact gggctggttc
     6421 acgcccgagc acaaggcccg cctcgcccgc gccaccaccg ccgacgccgc caacatcggc
     6481 aacctcgcgg tgagcatcgg cgggcccgcc atcaccgcga cgctcacgcc gctgacgatc
     6541 atcggtgtca cggtcgcggt ggactggcgc gtcgcgctgc tgttcgccgt gatcatgccc
     6601 gtcgcgttgc tggcactgcg cagggccggc cgcatcgcct cgatcgccga cgtcgaactg
     6661 gagcaggcag ccgcggacat cgcgggccgc gcgatcgagc tggggcaggc ccagccggtg
     6721 ctccgagccg caggccagag ctccaccggc acggcgcgga tgcgcgaggc actcgacgaa
     6781 caccgcaccg tctaccggcg cgggctccgg cgctccatgg ctcccgacct cacctacacc
     6841 ggcgtcatca tggcggggtt cgtcgcgatc ctcgtcgtca gtgcgctgtt gctgctcgac
     6901 ggcacgctcg gggtggccga ggtggtggca ctgctggtgc tggccgtccg gttcctcgag
     6961 ccgctcggca acctggtgga gctgatcggc gccctgcacg ccatggacaa cgctgtcggc
     7021 agggtccggg cgctgctcgc gacaccccca ttgcccgagg ccgaccggcc ggtgaccgag
     7081 ctgcccggca cgtcggtgga gctgtccggc gtcaccttca cctatcccgg cggcagcaca
     7141 cccgcgctcg cgggcgtgtc gttcacgtgc gcgccgggca gcacgaccgc gatcgtcggg
     7201 ccttccggat cgggcaagac cacggtgacc cggctgatcg cccggttctt cgatccccag
     7261 gagggctcga tccgcatcgg cggcgtcgac gtgcgtgagc tggatcagcg gacactgctg
     7321 gacagcattg ccgtggtgtt ccaggacgtt tacctcttcg acgacacgat cgaggagaac
     7381 ctgcggctcg ccaagcccga cgccaccgac gccgagctgg ccgaggcggc gcgcgcggcc
     7441 cgtctcgacg aggtagtcga gcggctgccc gaaggctggc acacccgagt cggcgagggc
     7501 ggatcgcggc tctccggtgg cgagcgccag cgcgtctcca tcgcccgcgc gttcctcaag
     7561 caggcccgca tcgtgctcat cgacgaggcc gcgtccgcgc tggaccccga gaacgagcgc
     7621 gccgtaagcc aggccatcgc aaggctggcc gccgaccggg ggcgcaccgt gctcgtcatc
     7681 gcccaccgcc ccgccaccct cgacgccgcc gatcacgtgc tcaccctcca caacggacac
     7741 gttgccgagg cgggcactcc tgcggggcta cgggccacgg gtggactctt cgcccggctc
     7801 tacgaccagt acgaccatgc ccgttcctgg cgcctcgacc gcgagagcgc gacggaggtg
     7861 ggctgagggt gcggaccgca ttccgcgggc tcgcggccgt gacgctgctc gccgtcacgg
     7921 cctgcgggcc gggcgacgcc gcgccgcggc agccaggcgg accggaggtc accgtgcgct
     7981 ccgccgtggg cgaggtgacg ctgcccgtca ccgacaccgg gatctgggcg ctggacgagg
     8041 cgagcgcact gcacctgctc tcgctcggtg tcaggccgac gcacgcggcg cgaaacgcct
     8101 actccggcga tgagatcgtg acagcctcct acgcgctgct ggaggaggcc ggcgtcgagc
     8161 tcgtcccacc gcagcggccc gagctcgtcg ccagcgccga gcccgcgctg atcgtgggcg
     8221 tcgacttccc cgcccaccac gagcagcgcg cccagctcga gcagatcgcc ccggtgcttc
     8281 tcaccgacga caacctgccg tggcaggagc agctcgcgtt gctgggcgcc gtcaccgggc
     8341 acggcgagca ggccgacgcg ctcaccggac ggctgatggc ccaggtccgc gacaccgccg
     8401 ggcggatcgc cgcgtccgaa cacgccgggg cgtcggtctc agtgctgtcc gactgcggcg
     8461 accaggcgtg tgtgtacggc agcggacggg cgctgggcag cctgctggcg cagctggggt
     8521 tcacccggcc gcaggcccaa cgtgacaagg gcggcgagtg gggctacgac atggtctcgc
     8581 gggaacggct ggccgagcac accgcggaca tcgtcctctc gctcgtgggc tcgatcggcg
     8641 gggacctcgt ggccggcgac tcgccgctgc tcgacacgag ccgcgcggtg accgccccgg
     8701 tggatttcgg cgcgtggtac ggctcgggca cgctgaacct ggtgtggatg ctccacgacc
     8761 tggaggcgat cctgttcggc gacgggaaga ccgcgaccgc ggccgaagcc ggccggctgt
     8821 ggtcgaggct cgacggctag gtcagctatg ccgcgtctga caaacgccat tgccggctgc
     8881 gggggggccg cgcggcgctc ggctggtgcg ggacacccgc gcccgggcat gcgttggtgg
     8941 aaggcccaag cacggtccgt ccgcgagggc cttccaccgc ctggtgaggc actagactga
     9001 tcccgctcgc cgggcctgcc cggctgacgc agaacctcct ggtggcagag aacccggacg
     9061 ccacggccgg gccgggatcc aacggatgga atcttcgtgc ctgtccgggc aggtgtggaa
     9121 ttgctagcga atccgttgga gaacacgttc ttgagcaacg cccggaaccg ttccgaacaa
     9181 cttcctgcta tgggctcgcg gcacccctgt ttttgaatgt tcgaaaaatc agaatgacag
     9241 gggtgagatt ttcgcgactc cattgtccgg gccgccggtt cgtgcgcggc gagcccgcgg
     9301 cggcgctgcg aatgcgctcg tcaggagact tggcgggcct gcgtccgctg tcggaggcgc
     9361 ggcgccggga aactgccgga aatcggctca cccgggttca tttcacgtac cgcctgagat
     9421 attatctcca accatggcgg atggtagccg agacacagtc gtccccgccg gcgtcggtcg
     9481 tcatcgggca gtggcctcgc catgatctgg gaagtgctgg tcctcggttt tgtactcagt
     9541 ctcgacaatt ttcgagtctc gatcgcgctc ggtaccgtcc cattcggtct gaagcgcgcg
     9601 gtgcaggtcg cgctgacctt cgggctgtgg gacgcgatca tgccgctggt cgggctgttg
     9661 atcggcaaca agatcgggga atccatcggg gacgtcgcag aatgggtggg cgcggccgcg
     9721 ctcggcgcgt acggcctgta cctcgtgatc tcggccctcc ggaaccccga gccggacgag
     9781 ctggaccacc cgtgggcgct gttcggcatc ccgttcatgc tgagcctgga caaccttttc
     9841 gccggggcaa gcctggggat tctcgggttc tcgccgtggt tctccgccgc tgtcttcggc
     9901 atcatgacgg cggtgttgtc gctggtcgga ctgcggctgg ggcaggcagc ggctcgcctc
     9961 atccggattc gctcggacct ggtgagcggg gtcaccctga tcatcgccgc cgtggcgctg
    10021 ccgttggtgt tcgggggcta gggcgaaccc cgtgcggccg ggggatcagc ggaagcgcgt
    10081 cggcccgcga gtcggcgttg gctgcctcaa cggccttggc gaccaggccg tggtcgggcg
    10141 agaggtggca gaccgggtcg gtgcgggcgg cgtcaccggt gagctggaac gcctggcagc
    10201 ggcacccgcc gaagtccagc tcccgccggt cacagctccg gcagggattc ggcatccagt
    10261 ccgtcccccg gaacgcggtc atcaccgggg attcggccca gatccgctcc agcgtgtcct
    10321 cccgcacact ggcccgcggc aacggcaggg actgtgcggc cgggcagggc aggacgtctc
    10381 cgttcggcgt cacggtcagc tgccgggagg cccagccgcc catgcagggc ttcgggtagc
    10441 ggctgtagta gtcggggagg acgtagatga cgtccatgcg gttccgcaac cgctcgcggg
    10501 cggcccgcac gacgacctcg gcggcccgca gctgggcccg gctcggcagg agcgcgtcac
    10561 ggttccgcag ggcccagccg tagtactggg tgttggccag ctccacccgg tcggcgccca
    10621 cctcctccgc cagctcgagc acaccggcga cgcggtcgat gttgttccgg tgcagcacca
    10681 cgttcacggt gagcggccag cccagctcct tgaccacgcc catcgcctcg atcttgcgcc
    10741 tccacgacgg cgtcccggcg atccggtcgg agatggccgg ctcgtcggcc tggatgctga
    10801 tctgcacgtg gtccaggccg gctgcccgca gctgctcggc cctcggacgc gagagcccga
    10861 cggcgctggt caccaggttg gtgtagaggc caaggtcgtg ggcttccgcc acgatctccg
    10921 ccaggtcgcg ccgcagcagc ggctccccgc cggacaggtg gcactgcagg acccccaggt
    10981 cgccggcctc ggccagcacc cgccgccact cgtcagtggc cagctcggcg gagtagtcgg
    11041 ccatgttcag cgggttggag cagtacgcgc aggccagcgg gcaacggtag gtgagctcgg
    11101 cgagcaaccc gaaggggcta tccatctgcg agctccacgc agcgccgggc gacgagccgg
    11161 gtcaggaact gccgcacctc gtcgccgggg acggtctgat atcgcgcgcc gagctcggcg
    11221 acgatctcag ccacggtgtg ccgcccatcg cacagctcga ggatgtccgc gccgctgccg
    11281 ttcagaacca ccaccgtctc ggggagttgc aggatgggac gctgcctggt ccggcagaag
    11341 gtcagccgga cgtggcgtgc caaccgaggc gtgtccgaag tggacaatcc gccgccgggg
    11401 tcggttccgg ctgtgctcgg gtacatcgcg gtcactccgg gtatgcctgg tcgatggcgt
    11461 ccatcaggct ccacaggacg tcgcacttga acgacagcgc gtcgacggcg cgcgcctggg
    11521 actcggctga ccggcaggac gcggtgacca cctcgagggc gtgctcgcag tctcgggggg
    11581 cctgctcgag gcgggcgcgg aaataggcga gaccctccgg gtcgatccag gagtaccacc
    11641 gctcgaacgc ggccaggcgc tgcgccatca ggtcgggagc aaacagctcc gtgagtgagg
    11701 aggccaccgc ctccacccat gggcgggtcc gggcgaagtt cacgtagacg tcgaccgcga
    11761 accgcacccc ggggaccagg tgccggtggt cccggacctc ttcgcgggtc agcccggcgg
    11821 cctcgccgag gcgcagccac gcctcgatgc cgccctcgcc ggtggcagtg ccgtcgtggt
    11881 cgacgatccg ccggagccag cggcggcgga cctccgggtc ggggcagttg gagaggatcg
    11941 ccgcgtcctt gcgggggatg ttctcctggt agtagaagcg gttggccacc cagccctgga
    12001 tctgcccgcg gctcagccgg ccggtgttca tccgtacgtg gaacgggtgc tggtcgtggt
    12061 agcgccggga gtgggcccgc aacgtgccga cgaagccgtc cgcgccggtg ctcgcggtcg
    12121 cggttgtccc ggttgtcgtc ggcattgccc tacacctcga cctcgaggcc gtccatggcc
    12181 acctgcatgc cgctgtcctc cacgacgcgc cgctcgggcg agtcctccag caggatcggg
    12241 ttggtgttgt tcatgtgcac gaagatcgtc cgccctacgg cgagcgaggg cagctgcgcc
    12301 aggctgccgt cccgcccgtc gatgggcaga tgccccatct cccgggccgt cttgcctgcc
    12361 aggccgagcc gtaccagctc gtcgtcgcgc cagcaggacc cgtcgatcag caggcattgg
    12421 cagccctgga tctccatccg cagcaccggt gtgactgcct gcacgaccgg caggtacacc
    12481 agcgtccccc caccgcgccc gtcggtcagc cggtgaccgg cgacgcgtcc gtggaccacg
    12541 ctgggcacgt cgaacgcccg gcaggtcagc ccgtcggcaa aggccatctc ggcgccgggg
    12601 gccaccgccc gctgatcagg agccaacgcc ggtagtcggc gctgaccgca accgacgact
    12661 gggtgtgcgc gaggccggcc ccgggacgga cagcggcgca cacccggcag ccgcggttcc
    12721 actgcgggga gccgcctccg gccgccgagc ccggcactcg cggcaacacc atgacactcc
    12781 gtccgtggtc gccgtccgtg gtcgtccgag ccgtcgggag ggcgcgggac ccgggggtcc
    12841 agcgccgccc cacgtcccgt tagtcctcca gctgagcgac gtacatggtc acttcgggcg
    12901 cgactccgat ctcatcgaac tcgggcgtct cccacacagc gagctcagac tccatggatc
    12961 cacctcctct ctgccagacg gctccggcag gtggtctcac gacgctacga cgtttccggg
    13021 agggcgaacg tgatcagcgc gcttccgtgg ccggcgccga gcatgccggg gaggaatccc
    13081 tcggaccaag cgccccatcc gaccggcacg gcgacgtact gcctgccgtc gaccatgtag
    13141 gtcgtcgggt tgctgtggtg gccgcttccg cactggaact gccagagcag ctccccggtc
    13201 cgggcgtcga gcgcgttgaa ctccccggtc ggttcaccgg cgaacaccag gtcgcccccg
    13261 gtggcaagca ccgaggcgca catcggaagc tcgttgcgcc agcgccaacg ctcgtcgcct
    13321 gcggcgtcga acgcgctgat gcttcctgtc atctcctcga tatccacctg aacgccggcg
    13381 ccccagtagg ggatgctctc cctgaactcc cggcgtcgcc gggtggcggt ggccccgaca
    13441 tcttggaccg ggacgtagaa gagcccggtc ttgggactgt aggcggcatg ggtccattcc
    13501 ttggcgccgg ccggccccgg gtagaagtgg accggcaccc cctcctcgtc ggggtacacc
    13561 ttggccgtca cctggccgtc cctcgtgatc gccccccagg tgatccggtc cacgaagggg
    13621 gtgatctgga ccaacgcgcc gttcgtgcga tccaggacga agaagtagcc gttcttgtcg
    13681 aagtgtccga ggagcttgcg cccgtccgac tcgaacagga tgcactcgcc gatgctgtcg
    13741 tagtcccaca cgtcgtgtgg ggtgcactgg tagtgccagc ggatctggcc gccgtcgacg
    13801 tcgacggcga cgatgctgtc ggtgtacagg ttgtcgccct cgcggactcc tccgtcgaag
    13861 tcgggcgccg ggtttccggt gcccacgtac agcaggttgg tctccgggtc gaaggtcgcg
    13921 gtgatccagc agttcgcgcc accacgcgcc caggcctcgc catcggcggg ccaggtgtcg
    13981 gccccgggct ctccgggctt cgggaccatg tagcaacgcc actggtactc accggtctcg
    14041 aggttgaacg cgtccaggtg accgcgaacg ccgaactccc cgccggagct cccgacgatc
    14101 accttgtcct tcacgaccag cggcgcgacc gtggcgctct ctccggcccg cacgtccccg
    14161 taggtcttgt cccagacccg cttgccggtg gtggcgtcga gcgcgagcac atgggcattc
    14221 gccgtgacga cgaaaacctt ccccgctgcc acggcgacgc cgcggttcac gttcccgcag
    14281 cacagcgaca cgtcgaaggg gaccgcgtgc ttgtaccgcc agatctcgac acccgtcttc
    14341 gcgtcgagag cccagaccca gccgtcccag cctgcgagga acatgatccc gtcgacgacg
    14401 atcggggcgg cctcgaacga gtaggtcgac gcgcccgcga tcatcccggt cgtgccggcc
    14461 tggaagaccc aggcgggacc gatgcgcttg acgttctccg tgttgatctg gtccagcggg
    14521 ctgtaccgct gtccgttgta ggcgccgtaa taggtgagcc agttctgggg ttccgaccga
    14581 gcgttcagaa tgcgctcgta gttgaccccg cgaaccaccg gcggcgcgac gtctccccct
    14641 gggaccttgc cgctcaggtt tccctggtcg atggcctcgc ccgcgtccac atattcgacg
    14701 gtcatcgtgc gtcctccaat ctagggccgc ggctggtcgg gacggtcgag gcgagcctcc
    14761 ggtggaacgt ctcccagcac cacgatggcg ccggtcagtc cccggccttc gtcgttgccc
    14821 gtgggtgagc tgaaccagta gtagccaggg ccgtcgaggt tgagcttcgc ccttcctcgc
    14881 gaatgattca ccagccaaat gaattttctg tccccattgc tcggcaggag cgcgcagtgc
    14941 gtgttcaggt cgtcattgat gagttcgagc tcgatatcac ccccgtgggg catgaccaga
    15001 atcgagggat cccagctgat ctcatcgggc cggatccgga ttgtcgcctc cattcggcca
    15061 tcggccctct ccgtagcctg cccaatggtt ccggtcccaa gaacctgacc caatgccgcc
    15121 ttgttctgcg cgtccaaccc gagctcgtcc agtagaccgg ctcggtcctg cgcggtcgtc
    15181 atcgggcgtc acctcctcat ccaatcctgt atctgcttgg cacaggaagc acgcggtgcg
    15241 acatggcaat gggtcggctg accgaatccc cggattcgcc ggtgctgccg gcggtagcag
    15301 acttgaaggc gcgaatatga ttgtgattgc atgagaacca tcacatcgaa accaattgcg
    15361 tggtcttatt cctgaattgc aaaatcacca atcaagcaaa actctacgcc gggtgaatcg
    15421 caccgacaag ggcaagcgcc aagtcgggcg ggccatgccg ttcgcccgcc accaggtacc
    15481 gttcgtaccc gatttcccgc cgttacgagg gatcaggcca tgtcgtaccg gtcgaggttc
    15541 atgaccttgt cccacgcggc cacgaagtcg tgcacgaact tctcctcggc gtcgtcgctc
    15601 gcgtacacct cggccagcgc tctcagctcg gagttcgagc cgaacacgag gtcgacgcgg
    15661 ctggcggtcc acttgacctc accgatgcgc cggtcgcggc cctcgaacgt ctcagcgtcc
    15721 tcagccaccg gcgaccactc gatgcccatg tcgagcaggt tcacgaagaa gtcgttggtc
    15781 agtaacccgg gggtcgaggt gagcacaccc agccgggacc gcccgtagtt cgcgcccagc
    15841 acgcgcaggc cccccaccag gacggtcatc tcgggcgcgc tcagggtcag caggttcgcc
    15901 cggtcgacca gccggtgctc cgccggcagc cggtcgccct ttgcccggta gttgcggaac
    15961 ccgtccgcgg tcggctcgag cggcgcgaag gactccacgt cggtccactc ctgggacgcg
    16021 tccatgcgtc ccggggtgaa ggggacctcg acgtggtagc cggcggccgt ggcggcctgc
    16081 tcgaccgcgg cacatccgcc gagcacgatg acgtcggcca gcgagatctt cttgcccccg
    16141 gtctgagcgc cgttgaagga ctcctggatc ttttccaggg tgcgcagcac ctgcgcgagc
    16201 gtgtccggct cgttgacctc ccagcggcgc tgcggctcga ggcggatgcg cgctccgttg
    16261 gctccgccgc gcttgtcgct gacgcggaac gtcgaagccg acgcccacgc cgtggacacg
    16321 agctgggcgg ccggcagccc ggagtcgagg atcctggcct tgagcgcgcc gacgtccgtg
    16381 tcgtccacca gctcgtggtc gacggcgggg atcggatcct gccagagcag ccgctccttc
    16441 gggaccagcg cgccgaggta gcgctggatc gggcccatgt ccaggtgcgt cagcttgaac
    16501 cagacccgcg cgaacgcgtc cgccagcagg tccgggttct ccaggaagcg ccgcgagatc
    16561 ggttcgtaga ccgggtcgaa tcgcagcgcg aggtctgtgg tcagaatcgt cggggcgtgc
    16621 gtcttcgacg ggtcgtgggc gtccgggacg gtgccggccc cgccgccgtc tctcggaatc
    16681 cactgccaca ggccggcggg gctcagctcg aggtcccatt cgtagccgaa cagggtctcg
    16741 aagaagctgt tgtcccacct cgtcggcgtg ggcgtccacg taccctcgag tccgctggag
    16801 atggtgtcgg ttccctttcc ggtgccgtag ctgctcttcc agcccaggcc ctgctcctcg
    16861 atcggcgcgc cctcgggttc ggggccgagg tggcgttccg ggtcggccgc gccgtgggtc
    16921 ttgccgaacg tgtgccctcc cgcgatcagc gcgacggtct cctcgtcgtt catccccatg
    16981 cgccggaacg tctcgcggat gtcccgggcc gccgcgagcg ggtccgggac ggtgttcggg
    17041 ccctccgggt tgacgtagat gaggcccatc tgtacggcgg ccagaggatt ctccagctcc
    17101 cgcactccgc tgtggcgttc gtcgccgagc caggcgcgct cgtggcccca gtagacgtcc
    17161 tcgccgggct cccagacgtc cgtgcggccg ccggcgaagc cgaaggtctt gaagcccatc
    17221 gtctccagcg cgcggttgcc cgcgaagatc atcaggtcgg cccaggaaat cttgcggccg
    17281 tacttcttct tgaccggcca gagcagacgg cgcgccttgt ccaggttgcg attgtcgggc
    17341 cagctgttca gcggcgcgaa gcgctgcatg ccggcgcccg cgcccccgcg gccgtcgtcg
    17401 acgcggtacg tgcccgcgct gtgccacacc atccggatca caagcggccc gtagtggccg
    17461 aagtcggcgg gccaccactc ctgcgaggtc gtcagcacct cgtcgacatc cctcgccagt
    17521 gcgtcgaggt cgagcgtccg gaactccgcg gcgtagtcga agtcctcgcc catggggtcg
    17581 cccgcggcgg ggtgtttccg gaggatcgtc agattgagcc ggttcggcca ccagtcgcgg
    17641 ctgctcgcgc cgccagtcgg gtgaccgcgg cgcccggccg ggacggagag gccgaggccg
    17701 gccgcgttcc cgctgttgct ctcgccgacg gtgctgtccg aggcgtccgg gctgtcagac
    17761 acgggaatcc ttccgagaac agagattgtg ctggggaact cagatttcca gcgcgcgacg
    17821 cacggccggc gcgttccgcc gggacaccgg caccatcgtg ttcgtccggt cgtccatgac
    17881 cagggacaac tcgcccttgc gcccgcgttc gacctcgcgg atgcggctga ggttgaccac
    17941 ataccgtcgg tgcacccgca ggaagccggc atccgccagc tcaccgtcga gcttgtccag
    18001 gccaggggag gcggctctca atcgcccctg gtcggtggcg agcaacacgt cgtttccttc
    18061 cgattcggcg aaggcgacct ccggtagccg gagcagcacc atccggttgt cgcgcgtcgc
    18121 gaccagtcgg cgcggctgcg cacgagggga tgcggacgct tccgcctggg gcaacggcgc
    18181 cccgtcggag gcgccgaacg agaccaggtt cccgatcagg cggccggaac tgaagacggg
    18241 gcggatgctg atcgaggtcg gctcatcggc gagatgggtg aagatctgcg tcgagccgac
    18301 ccagtcggga ttgtgggctg cctgccggac ggcataccgg acggctccga ccagttccgg
    18361 cagtccgggg ttccagcgca gggtggggtc gaccgccggg gttgaggccg ggacgcccat
    18421 gagcacactt gccatgtcgt cggcgatcac caccttgccc gcggtgtcca gcgcggcgag
    18481 catcgccgtg gagtgggccc tggcctgggt gaacgcggcg accaactccg cgccgctgtc
    18541 ccgggcgtgc ttcttcagcg tgcattgggt caaggtggcc gcgttcgcca gccagcttcc
    18601 cgcggcggcg ggaagctggc tgcgccagca ggagatgttc agtaccgcga tcggctccct
    18661 ggtcaccacg tcacgcaccg cgacgcccgc acagacccag ttgtggaacg cctggcacca
    18721 gtgctccggt cccctgatcg atatcgggcc gtgcgcctcg agcgccgtgc ccatgccgtt
    18781 ggtgccggcc gcgcactcgg accagcagaa ccagggcgcc agattggagt cggtggccct
    18841 ggcgagggtg gcctggtcac cccactcggc caggatccgg ccagtggcat cggtgacggt
    18901 gacgacgcca ccgaggttgc ccatttcatg cgccacggag gcggcacgaa aacccagctc
    18961 agcgaatacg acatcgtgct cgggcgtacg gtcgggctcc gcgacggcta tcggagccgc
    19021 tgtgaggtgc gggtcgaccc ggtactgctc tcggcagcga tgccaggaga tcgccaccag
    19081 gggccggaca gccgggactt gatcctcgcc ctgcacgaac cgttcccatg ccgcgagcac
    19141 ggtgccgctg cccgggttcg cagccacggg ctcaagccga tgtgcatccc tcatggtgga
    19201 gaaccgccct tggttcatcc ccaacgcccg acggcgtgcc cgtggtccgc gctggtcccc
    19261 gctggtcgcg gccgggccca cagcggactg gacaccgcgt cgcgcgtctt cctgccttgt
    19321 cattcgttcc aggctgtgtc acagaccggc acttctcact gtaggccgaa gtcgcggcag
    19381 cgctacacca tctttggcct ggatacccgt tgccggccgc gcacgtccct ctccgggtcg
    19441 cggatgcgga atgtcgcttg cgggacgaga tcggcggacg tttcaccggg gccgagcggg
    19501 tctcggggcc cgcgttgtgc cgacatcggc cgccgactcg caaccggagc cgacagggtt
    19561 tgcccgtgcg tgagcgtcac cgtgaacgcc gttggtgctg ccggcaggca ggtgggcagt
    19621 gctcggactg ctcggtggtt tctgggtggg tgcgtgtggt caggccgagg agccgggtca
    19681 gggcggtgaa gccgtcgtcg gtgccgggcc agtgcgcgcg aaccgggtcg aggccggcgc
    19741 ggcggaccat cgagcggagg acggcggtgg cgatgatggc gtcgtcggcg tagccgagga
    19801 cggggatgaa gtcggggacc agatcgatgg ggatggcgag gtaggccagc agcagcccga
    19861 gccggatccg gactccgcgg ggcagagtgg tgtccgcggc cagcctgcgc accaggcgca
    19921 gcacatcagg cagcacccgc acggcctcac gcaacagtcc tccgcgcgga cgcaagacca
    19981 tcagtgcgat ccccaacgcc agccaggcca gtacgagcgt ggcgacgacg ctgatcagga
    20041 ggtcccacca gaacgagccg gtcacgagtc cgccaccgcc cgcaaccggc gcgggcttcg
    20101 ccgtgcaacg gggtcaggtg cctctgcttg gaaggctgcc tgctcgaacg ccgccaggtc
    20161 ggcggcggcc tcgtccaccg cgtcccgggc agcccggccg ccgggcgcgt cgaagtagtc
    20221 cctggcggcg atcttggtca gccaggtgcg gaagcgtgcc aggtcggctt cggactcctc
    20281 gacctcggcg taggttgccc ggcctcgagc gcgctcctgc gcgagttcct gccgcagggc
    20341 gggcaggcgg tccaggactt cggcgtactc ggcgtcgcgg gcggcattca tctcggcgac
    20401 cacggcctgt tcctcggcgg gctcggtgaa gcgcattcgc agtacgcggg cggtgccgcc
    20461 ctggtggcgg acccggtcga ccagccgccg gacctgccgc accacctcgt cgtcggcggg
    20521 cagcaggcag accgattgct gcaggtagag cgcgccgagt gagcgcagct tgcgccacac
    20581 ccgcacgcgt agcgtgccgg cagccccagc ggttgagatg ctgatcatca accactccct
    20641 gccggcattg ctggtcacac agccatgtta cagccgtaac aacccggcat gttggctctc
    20701 gcacctgtcg acgtcgccgc gcggctgcgg cggtcccgca accacggctg ggcgaccggg
    20761 ccggccccga cggcggccgg ttgagcttcc gccgacaggg gccggggctg cccgcggagc
    20821 cgcagttgcg tgactcagcg cgggatcggg gtgccgatcg cccgtcgtgg ggtcgaggac
    20881 ccggcccgaa ccgctgtcgc gcgacgggtg ttctcgccga cgtgtcgcgg gtcaggtggg
    20941 gaggggggtt ctgccgtagg tggtggtgcg ttggcgggag ggtcgtccgg
//
