LOCUS       NZ_SWMS01000025        31377 bp    DNA     linear   CON 10-DEC-2024
DEFINITION  Prauserella endophytica strain CGMCC 4.7182 Scaffold25, whole genome
            shotgun sequence.
ACCESSION   NZ_SWMS01000025
VERSION     NZ_SWMS01000025.1
KEYWORDS    WGS; RefSeq.
SOURCE      Prauserella endophytica
  ORGANISM  Prauserella endophytica
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Prauserella; Prauserella
            coralliicola group.
REFERENCE   1  (bases 1 to 98716)
  AUTHORS   Liu,J.M., Habden,X., Guo,L., Tuo,L., Jiang,Z.K., Liu,S.W., Liu,X.F.,
            Chen,L., Li,R.F., Zhang,Y.Q. and Sun,C.H.
  TITLE     Prauserella endophytica sp. nov., an endophytic actinobacterium
            isolated from Tamarix taklamakanensis
  JOURNAL   Antonie Van Leeuwenhoek 107 (6), 1401-1409 (2015)
   PUBMED   25832628
REFERENCE   2  (bases 1 to 98716)
  AUTHORS   Li,Q.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-APR-2019) Yunnan Institute of Microbiology, Yunnan
            University, No. 2 Cuihu North Rd, Kunming, Yunnan 650091, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 10.16x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_005146945.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 16:32:08
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,852
            CDSs (total)                      :: 7,795
            Genes (coding)                    :: 7,703
            CDSs (with protein)               :: 7,703
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 34 of 92
            Pseudo Genes (incomplete)         :: 69 of 92
            Pseudo Genes (internal stop)      :: 2 of 92
            Pseudo Genes (multiple problems)  :: 13 of 92
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 18:09:25
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 67339
            Orig. end                         :: 98716
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            SWMS01000025.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..31377
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="arylpolyene"
                     /region_number="1"
                     /rules="(APE_KS1 or APE_KS2)"
                     /tool="antismash"
     cand_cluster    1..31377
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(APE_KS1 or APE_KS2)"
                     /kind="single"
                     /product="arylpolyene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..31377
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[20000:21098](+)"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..21098
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
     misc_feature    139..149
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     gene            complement(1020..2027)
                     /locus_tag="FCN18_RS31320"
                     /old_locus_tag="FCN18_31315"
     CDS             complement(1020..2027)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009156720.1"
                     /locus_tag="FCN18_RS31320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_31315"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_112266650.1"
                     /transl_table=11
                     /translation="MSPSIKDVAVRAGVSVGTVSNVLNHPERVAESTRTAVQSAIAALG
                     FVRNSSAAQLRAGTSRSIGLIVLDMANPFFHDVARGVEQVADELGYAVVLCNSDDQTSR
                     ENRYLQVLEEQRVRGVLITPIEVSSDRLDALRRRGTPTVLVDRHDPRVNCCSVAVDDVV
                     GGELAGAHLVAQGHERIVYFSGPLGLSQCADRLTGLRRSVAAAGLDPDAVIEVVEIPVM
                     NARSTHDVARARFEQGERATAAFCANDLMALGVLRAALSTGRRVPGDLAIVGYDDIEFA
                     ADAAVPLTSIRQPTQQIGRAAAQLLVEECDNPDTHAHQQVMFKPELVTRESTRH"
     misc_feature    complement(2214..2227)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.1"
                     /tool="antismash"
     gene            2253..3770
                     /locus_tag="FCN18_RS31325"
                     /old_locus_tag="FCN18_31320"
     CDS             2253..3770
                     /EC_number="7.5.2.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009156719.1"
                     /locus_tag="FCN18_RS31325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_31320"
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="WP_137096769.1"
                     /transl_table=11
                     /translation="MAAPEHTGVPLLELRDVTKSFQAVRALRGVSLALRAGEVHALAGE
                     NGAGKSTVVRIIGGEHQPDSGEVLLDGEPVRFSSPREAQQRGVAVIHQEPIQFPDLSVA
                     ENVFMGRQPLRPGRRIDRRAMHRRASEVFEQLGVPIDPARQTRGLSIADQQIIEIAKAL
                     VADARIIVMDEPTAALSAVEAERLFRVARGLAERGAALLFISHRLDEMYALCDRVTVLR
                     DGSFVVTERMDDIDNDTLVRRMVGRSVEQLFPKRDTEVGDEVLVVDGLTRAGVYRDISF
                     SVRRGEIVGLAGLVGSGRSEVVRAVFGVDDRDSGTVTVNGKPLPKSKPRTAIEQGIALV
                     PEDRREQGLVLELSIERNASLARLKQVSPGGLTRQSRERELARTWGERLSLKFGSLSDP
                     AATLSGGNQQKVVLGKWLATEPSVLIVDEPTRGIDIGAKVEVHALLSDLAAEGMAVLLI
                     SSELPEVLGMADRVLVMHEGRITAELSRDEATEESVMYAATGNGSAA"
     misc_feature    2301..2316
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.23"
                     /tool="antismash"
     gene            3767..4768
                     /locus_tag="FCN18_RS31330"
                     /old_locus_tag="FCN18_31325"
     CDS             3767..4768
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1113:
                     inner-membrane translocator"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009156718.1"
                     /locus_tag="FCN18_RS31330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_31325"
                     /product="ABC transporter permease"
                     /protein_id="WP_113642243.1"
                     /transl_table=11
                     /translation="MSRLRALLSGRELSIVVALVAVVGVTTATNPSFLSAQGIHDLFLN
                     ASIIALLAIGQTLLVITRNIDLSVGSVMGLTAYMSGQMFIADHDTPTILVVLAGMALGA
                     ACGAFNGALVAIAKVPALVVTLGTLYVFRGINYGWASATGVHQINADQMSQGFLAFGSG
                     SILGIPHLTLIALAALVIAAYALHNWRSGRELYAIGSNPQAARLAGIPAGKRVFTAFVV
                     SGALVGLAGVLHASYFGTINASVGTGRELAVVAAVVVGGVAIFGGSGTVLGAVLGALLL
                     TTITSALPILGVPAFWQRAVDGAALLLAISLDRAVMVRLAERLRKERSLRRA"
     gene            4761..5816
                     /locus_tag="FCN18_RS31335"
                     /old_locus_tag="FCN18_31330"
     CDS             4761..5816
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1113:
                     inner-membrane translocator"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009156717.1"
                     /locus_tag="FCN18_RS31335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_31330"
                     /product="ABC transporter permease"
                     /protein_id="WP_112265181.1"
                     /transl_table=11
                     /translation="MREKLLRWESVLLLLCIFVFVWGSASTPGFAETDNISFLLLDYTE
                     VALLALALLPIILTGEIDLSVASILGFCSALTGVLWDAGMSFESIVPIVLVAGAVLGSL
                     NATLIVRFALPALAVTIGTLGLYRGLAYVVLGDGAVTGFPDVYRPIATEEIPGTFLPYA
                     TLVVLLLGVLVAVVVHYTPVGRSLYAIGLGEQTARFSGIRVQRIKFVLYIVSGILCAIA
                     SLVYTLRYNSARADNANGMELIAVAAVLLGGVSIFGGRGTVVGVASALLLMAGLRNVLF
                     LNDVTNEIQNVINGLLLIISVLVPVVANLVRRRRTPAAAAIPGSPPPQETLPDPVGATA
                     APHGTPEEDQR"
     gene            5813..6901
                     /gene="rhaS"
                     /locus_tag="FCN18_RS31340"
                     /old_locus_tag="FCN18_31335"
     CDS             5813..6901
                     /GO_component="GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA]"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0015153 - rhamnose transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0033296 - rhamnose binding [Evidence IEA]"
                     /GO_process="GO:0015762 - rhamnose transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="rhaS"
                     /gene_functions="transport (smcogs) SMCOG1205: ABC
                     transporter, carbohydrate uptake"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009156716.1"
                     /locus_tag="FCN18_RS31340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_31335"
                     /product="rhamnose ABC transporter substrate-binding
                     protein"
                     /protein_id="WP_112265180.1"
                     /transl_table=11
                     /translation="MIHHRWSGKRALLAVTSMGLAAALVAGCGGTTKDSAESGSGSGAN
                     SEKVADPNAPIKEGLQIAFLPKEIDNPYENIVDQGGIAAVAELKGTGKEVGPSDASASS
                     QVSYINTLVQQNQDAIVIAANDPNAVAPALKDAMAKGIAVVSYDSDAAVDARQVFVNQA
                     DSESIGRSQIQMVSEQIGGKGKIAILSATPNATNQNTWIEFMKDELKKPEYKDIELVTV
                     AYGDDDDQKSFQETQALLSSNPDLKAIVSPTTVGISAAARYISSSPYKGKVVLTGLGTP
                     NQMRQFIKDGTVKEFALWDPEQLGYLAGYAAAALASGQITGKEGEVLKAGKLGERKIGK
                     NGEIILGPPTTFNADNIDEYDF"
     gene            6901..7230
                     /locus_tag="FCN18_RS31345"
                     /old_locus_tag="FCN18_31340"
     CDS             6901..7230
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005460116.1"
                     /locus_tag="FCN18_RS31345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_31340"
                     /product="L-rhamnose mutarotase"
                     /protein_id="WP_112265179.1"
                     /transl_table=11
                     /translation="MATGPRRVCFLLRVKPDRMDEYRRRHAEVWPEMRAALRETGWGNY
                     SLFLAPDGLLVGYFETDDLDAALEGMAAKEVNARWQAEMAEFFENLDGAPDEGIVPLPE
                     VFHLD"
     gene            7256..8422
                     /gene="rhaI"
                     /locus_tag="FCN18_RS31350"
                     /old_locus_tag="FCN18_31345"
     CDS             7256..8422
                     /EC_number="5.3.1.14"
                     /GO_function="GO:0008740 - L-rhamnose isomerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019299 - rhamnose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="rhaI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019818979.1"
                     /locus_tag="FCN18_RS31350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_31345"
                     /product="L-rhamnose isomerase"
                     /protein_id="WP_113642244.1"
                     /transl_table=11
                     /translation="MSDYSAVKAALREQRIETPSWAFGNSGTRFKVFAQEGIPRDAYEK
                     IADAATVHRFTGVAPSVAVHIPWDRVDDYADLAKHAENLGVRIGAVNPNVFQDDDYRLG
                     SVCNPDPAVRKKALGHLLDCVDIMDVTGSRDLSIWLADGLNYPGQDSIADRQARLEEAL
                     AAVYERLGENQRMLLEYKFFEPAFYATDVPDWGTSYAHCLELGEKAQVLVDTGHHAPGT
                     NIEFIVAFLLRKRRLGGFHFNSRFYADDDLMVGAADPYQLFRIMVEIVLGGGLDAASGV
                     AFMLDQCHNIEPKVPALIRSVLNVQEATAKALLVDADALRKAQQAGDVLGANGILTDAF
                     ATDVRPLLGELREEMGLDPDPMSAYKRSGYAERIVAERVGGTAAGWGA"
     misc_feature    7280..7293
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.61"
                     /tool="antismash"
     gene            8424..10460
                     /locus_tag="FCN18_RS31355"
                     /old_locus_tag="FCN18_31350"
     CDS             8424..10460
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (421-521). E-value: 5.1e-09.
                     Score: 28.2. Matches aSDomain:
                     nrpspksdomains_FCN18_RS31355_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009947051.1"
                     /locus_tag="FCN18_RS31355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_31350"
                     /product="bifunctional aldolase/short-chain dehydrogenase"
                     /protein_id="WP_137096770.1"
                     /transl_table=11
                     /translation="MTNQAVTDLLARSHALGADRRNTNYAGGNASAKGTDLDPATNAEV
                     ELMWVKGSGGDLGTLKETGLAVLRLDRMRALVDVYPGEEREDEMVAAFDYCLHGKGGAA
                     PSIDTAMHGLVDAAHVDHLHPDSGIAIATAVDGEELTRKVFGDRVVWVPWRRPGFQLGL
                     DIAAIKQANPQAIGCVLGGHGITAWGDTSEQCQAHSLEIIRTAEAYLAEHGDPEPFGKA
                     LPGYEPLPEEERRARAALLFPVLRGLASTDSPQLGHFTDSPEVLEFLAHEKHPALAALG
                     TSCPDHFLRTKVAPLVVDLPGSAPIDDVLDRIRELHAAYREDYAAYYRRHATPDSPPMR
                     GADPAIVLVPGVGMFSFGRDKQTARVAGEFYVNAINVMRGAESVSTYAPIPESEKFRIE
                     YWELEEAKLRRMPKPKPLATRIALVTGGGSGIGRAIAHRLAAEGACVAVADRDLSSATE
                     VAEEIGNTDRAVAVAVDVTDEDGIAAAVAATSLAFGGVDLVVNNAGLSVSKPLLETSAK
                     DWDLQHDVMARGSFLVSREAARVMVAQGLGGDIVYIVSKNGVFAGPNNIAYGATKADQA
                     HQVRLLAAELGEHGIRVNGVNPDGVVRGSGIFASGWGAQRAAVYGVPEEELGAFYAKRT
                     LLKREVLPEHVAGAVFVLTAGDLSHTTGLHIPVDAGVAAAFLR"
     aSDomain        9687..9986
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FCN18_RS31355_PKS_KR.1"
                     /evalue="5.10E-09"
                     /label="FCN18_RS31355_PKS_KR.1"
                     /locus_tag="FCN18_RS31355"
                     /protein_end="521"
                     /protein_start="421"
                     /score="28.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="ALVTGGGSGIGRAIAHRLAAEGACVAVADRDLSSATEVAEEIGNT
                     DRAVAVAVDVTDEDGIAAAVAATSLAFGGVDLVVNNAGLSVSKPLLETSAKDWDL"
     CDS_motif       9690..9755
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FCN18_RS31355_0001"
                     /evalue="7.50E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="FCN18_RS31355"
                     /protein_end="444"
                     /protein_start="422"
                     /score="15.4"
                     /tool="antismash"
                     /translation="LVTGGGSGIGRAIAHRLAAEGA"
     gene            10639..12051
                     /locus_tag="FCN18_RS31360"
                     /old_locus_tag="FCN18_31355"
     CDS             10639..12051
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005460104.1"
                     /locus_tag="FCN18_RS31360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_31355"
                     /product="L-fucose/L-arabinose isomerase family protein"
                     /protein_id="WP_113642246.1"
                     /transl_table=11
                     /translation="MSDTKRRPRIGLVAGGLGAYWPQFPDLLPTLKQSSAYVSERITGF
                     DAEIVDVGFISDAQEGAAAAEKLRAAGCDLIVGFLTTYMTATMLMPIAQRSGAPVLLIN
                     LQPTESMDHATFDTGQWLAYCGACPLPEMANAFRRAGVEFRSVSGHLRDERAWAKIGRW
                     ISAAAVRKVLRHGRHGLMGHLYPGMYDVSTDLTMVNAHFGGHVEVLEFDDLRVRVEQVT
                     DADVAAKVAEAESVFELDASVNREDLEWGAKVAVGLDRLVADFDLDSLAYYHRGLDGET
                     HERLGAGMILGASLLTARGVPAAGEYELRTSIAMLIMDVLGAGGSFTELQALDFERGHV
                     EMGHDGPAHLAISAKKPLLRGLGVYHGKRGWGVSVEFDVAHGPVTLCGIGQDREGRYSL
                     IVSEGEVVDGPLMRIGNTTSRVDFGRDPGEWTDEWSASGVAHHWALGVGHRAAELRAVA
                     SLLGVPLVEVGR"
     gene            12048..13448
                     /locus_tag="FCN18_RS31365"
                     /old_locus_tag="FCN18_31360"
     CDS             12048..13448
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1210: glycerol kinase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009156711.1"
                     /locus_tag="FCN18_RS31365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_31360"
                     /product="rhamnulokinase family protein"
                     /protein_id="WP_170200625.1"
                     /transl_table=11
                     /translation="MTAFVAVDLGATSGRVMLGQVIEGTIDLTELRRFRTGPRERPGGG
                     LRWDVEEMYAEIVAGLREAEGAEPVSIGIDSWAVDYGLLDADGRLDGDVRCYRDPRTDG
                     MAARLRERVDDETLYRITGLQYLPFNTIYQLLAEPEERLAGKTMLLLPDLIGYRLTGEF
                     GAEVTNASTTALLDATTRQWSTELADKVGLPAGLLPPLRQPGEPIGTAPGGVPVVAVAS
                     HDTASAVAAVPALGDRFGYVSCGTWSLAGLELPAPVLTDEARRANFTNEAGIDGTVRFL
                     RNTMGLWLLTESLRVWRERGHDIRLDDVLKAAMREPAFRSIVDADHPVFLTPGDVPARI
                     ATLCRESGQPVPETPPAVVRTILESLALAHADSLRTAARLADRELDVVHLVGGGALNEP
                     LCQLTADACGLPVLAGPVEASALGNVFVQARAAGVLADVPSSAPLARYEPRGEQAAWRT
                     AAERAGLG"
     gene            13445..14179
                     /locus_tag="FCN18_RS31370"
                     /old_locus_tag="FCN18_31365"
     CDS             13445..14179
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1261: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015787967.1"
                     /locus_tag="FCN18_RS31370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_31365"
                     /product="(Fe-S)-binding protein"
                     /protein_id="WP_137096772.1"
                     /transl_table=11
                     /translation="MSAPRVALFATCLTDTLYPETGKAVVRLLTRLGCDVDFPLAQTCC
                     GQMHYNTGYHDHARPLARDYAATFEGYDHVVAPSGSCGAMVREIHPSLCGTSPAVERTY
                     ELSEFLVDVLGVTDVGAYFPHRVTYHPTCHSLRMLGVGDKPLSLLRAVKGLELVELPQA
                     EQCCGFGGTFALKNAETSTAMLADKMRCVQDTGAQVLSAGDNSCLMHIGGGLSRLRTGV
                     RTVHLAEILASTEEEPWASATR"
     gene            14158..15594
                     /locus_tag="FCN18_RS31375"
                     /old_locus_tag="FCN18_31370"
     CDS             14158..15594
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /GO_process="GO:0006089 - lactate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005441969.1"
                     /locus_tag="FCN18_RS31375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_31370"
                     /product="LutB/LldF family L-lactate oxidation iron-sulfur
                     protein"
                     /protein_id="WP_137096773.1"
                     /transl_table=11
                     /translation="MGVRNPVTWLGSPVFPKAAHEALADTQLRRNLRKATTTIRTKRAG
                     VVAELDDWERLRQAGEAIKDDVLANLDTYLVRLEKAVTARGGVVHWARDAEEANRIVLD
                     LVRAEGADEVVKVKSMATAEIGLNEALEAGGVRAVETDLAELIVQLGDDRPSHILVPAI
                     HRNRAEIRDVFRRGMAEEPASDEPRDLAEAARRHLRRKFLSAKVAISGANFAVADTGSI
                     VVVESEGNGRMCLTLPETLITVMGIEKLVPSWQDLEVFLQLLPRSSTAERMNPYTSVWS
                     GVTPGDGPRRFHLVLLDNGRTATLADQVGRQALRCIRCSACLNVCPVYERTGGQAYGSV
                     YPGPIGAILAPQLAGDMHDEQAASLPYASSLCGACYEVCPVRINIPEVLTHLRAEAVRA
                     KGKRTPEAIAMAAAAWVFADPKRYEAAQKAGSLSRLLARDGRIKRLPGPGAKWTDSRDA
                     PAVPKESFRAWWRKNHVQRS"
     gene            15578..16186
                     /locus_tag="FCN18_RS31380"
                     /old_locus_tag="FCN18_31375"
     CDS             15578..16186
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020418868.1"
                     /locus_tag="FCN18_RS31380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_31375"
                     /product="lactate utilization protein C"
                     /protein_id="WP_112265169.1"
                     /transl_table=11
                     /translation="MFSARDEILARIRAVNRASPVPIPRDYERTRTVPDVLGLLDERVT
                     DYKAIVHRVAEAQLPDRIADRLALRSVSTMAVPSDVPPEWRVPAVTWLPDEPPLPLAEL
                     DTVDGVLTGCAVAIAETGTIVLDAGAGQGRRMLSLVPDYHLCVVRADQVVTSVPEALAR
                     LEPGRPLTFISGPSATSDIELDRVEGVHGPRTLEVLIAT"
     gene            complement(16286..16711)
                     /locus_tag="FCN18_RS31385"
                     /old_locus_tag="FCN18_31380"
     CDS             complement(16286..16711)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005439339.1"
                     /locus_tag="FCN18_RS31385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_31380"
                     /product="PIN domain-containing protein"
                     /protein_id="WP_137096774.1"
                     /transl_table=11
                     /translation="MIAVRYLFDTSALVRVLRDARARAGWEQQIEAGLVATCPLVELEF
                     LHTARSKADRDQLVELIGAAFTWLPVPDEVFRRAFEVQDALTAAGTHRSAGAVDLLLAA
                     TAELAGLTLVHHDHDFEQIAEVTGQPVARLAPPGSIS"
     gene            complement(16708..16917)
                     /locus_tag="FCN18_RS31390"
                     /old_locus_tag="FCN18_31385"
     CDS             complement(16708..16917)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006237182.1"
                     /locus_tag="FCN18_RS31390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_31385"
                     /product="type II toxin-antitoxin system VapB family
                     antitoxin"
                     /protein_id="WP_112265165.1"
                     /transl_table=11
                     /translation="MAKVLIDIDDEALAEASRLLGTKTKKDTVNTALRETTQRIRRAKA
                     LARLAELGESGAFDELLDKESYRR"
     gene            complement(16962..19727)
                     /locus_tag="FCN18_RS31395"
                     /old_locus_tag="FCN18_31390"
     CDS             complement(16962..19727)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025: diguanylate cyclase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009156707.1"
                     /locus_tag="FCN18_RS31395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_31390"
                     /product="EAL domain-containing protein"
                     /protein_id="WP_137096775.1"
                     /transl_table=11
                     /translation="MEARTHAEVTTGTDPDHEIVADLALAAGSSARWSVGAGDGRVTWS
                     AGLGAMFGLPEEAEADIRRTLLELISPIDVTLRNAPPWDNFELEQSLETPEGEVRWIRF
                     LARPRPGGTKAGLLGIATDVTERHGSEQALADLADRYRLLVELSPDAICVHEGGKLVYV
                     NPAALRFAAVDSADELLGRPITDFVDPASVPAMLHRIEGLTTPGATSEPTEVQLKRFDG
                     DSMLVESVSVRTTWQGRPAFQVIMRDITAQKAAEAALHYQAALVSHVSDAIIATTADGI
                     VTSWNPAAEAVYGRSSTEAIGRDVGELVGAPLDPERVMAAGGVVEGDHRTADGSTLAIR
                     VSAAEMHDGYVLVCADETPRRRAERRYSTVVAALDEGVVVIGPDGMIESANPAAARILG
                     MPNTVLRKSSPTRFPLYGESGARLAATEYPFSEVLATGQAQNGRVLRLQRPDGTYVWLS
                     MSCRPLDPDAAPPSTVVTSFTDITERRAIGEQLEHDATHDPLTGLANRTLVLQRLDGAL
                     AEPDREGLACVLFIDLDKFKLINDSLGHSTGDQVLRVVGQRLRHCVRATDLVGRLGGDE
                     FAVVTFDVSGDTGIRSLIGHLRASLTKPIGLDGRQLRVDASVGIVTAAPGDARSAEDLI
                     RDADVAMYEAKTRGRGRYEFFDVELRERVQRQLRLEQDLREAVVDGQLWMAYQPVVDLR
                     TCRTVAVEGLMRWHHPTHGAISPVEFIPLAEESDLINLIGDYMLRTTTEEIASQRAARN
                     LDTRLTVNLSARQLDDAALVPTVEEALRRTGLPPQTLCLEITESALMRDPEVAGGALSA
                     LRGLGVRLAIDDFGTGYSSLAQLWRLPLDTLKIDQSFVAGIGRPGKSEAEAIIRGIVTM
                     AHSMGLTVIAEGVETDRQLEVLRELNCDQAQGYRFGRPVSAGELFPRMAG"
     misc_feature    19860..19875
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.44"
                     /tool="antismash"
     gene            20001..21098
                     /locus_tag="FCN18_RS31400"
                     /old_locus_tag="FCN18_31395"
     CDS             20001..21098
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (115-332). E-value:
                     7.8e-29. Score: 92.7. Matches aSDomain:
                     nrpspksdomains_FCN18_RS31400_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020418266.1"
                     /locus_tag="FCN18_RS31400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_31395"
                     /product="beta-ketoacyl synthase N-terminal-like
                     domain-containing protein"
                     /protein_id="WP_137096785.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.4e-19, bitscore:
                     63.2, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="APE_KS2 (E-value: 5.7e-44, bitscore:
                     143.3, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLWDGLVSGKSAAVLTGGFGRNRDESAWVAAVPEGGDPADGRGRF
                     ARAMRASAREAIEDAKGRGWTPGRRVGLLHAVVIGEAYLWKDFYVTDKGKLRLRDYLAL
                     MPSTPMSTFMQEYGFHGPAMNVSAMCASGNAGLLTAKAWLDAGIVDDVVLVATDLSLTP
                     ENVLHFTRLGVAVANREPLDGCRPFQEGSRGFVMGEASVGMVLSNRSDKPYAVTLGGAM
                     SHDAYHVTSIDPEFPEVRRCFVEALDNARVPAEEVRYVNAHGPGTKQCDRVEAAIVEEM
                     FRPDTGIYSVKPLAGHCQGAASAVEVAVAAIGYERGVIPAPPSVAEAHPQLLHGEFGVD
                     GGLTVKSSLGMGGHNSVVVLGPARA"
     aSDomain        20346..20996
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FCN18_RS31400_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="7.80E-29"
                     /label="FCN18_RS31400_PKS_KS.1"
                     /locus_tag="FCN18_RS31400"
                     /protein_end="332"
                     /protein_start="115"
                     /score="92.7"
                     /tool="antismash"
                     /translation="EYGFHGPAMNVSAMCASGNAGLLTAKAWLDAGIVDDVVLVATDLS
                     LTPENVLHFTRLGVAVANREPLDGCRPFQEGSRGFVMGEASVGMVLSNRSDKPYAVTLG
                     GAMSHDAYHVTSIDPEFPEVRRCFVEALDNARVPAEEVRYVNAHGPGTKQCDRVEAAIV
                     EEMFRPDTGIYSVKPLAGHCQGAASAVEVAVAAIGYERGVIPAPPSVAEAHPQL"
     gene            complement(21226..21660)
                     /locus_tag="FCN18_RS31405"
                     /old_locus_tag="FCN18_31400"
     CDS             complement(21226..21660)
                     /GO_function="GO:0004601 - peroxidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005441960.1"
                     /locus_tag="FCN18_RS31405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_31400"
                     /product="OsmC family peroxiredoxin"
                     /protein_id="WP_112266644.1"
                     /transl_table=11
                     /translation="MASRDSTTHWTGGLNSGKGTVTLDSSNSGQFEVTFPRRIGEPEGT
                     TSPEELIAAAQSSCLAMNLAGVLEKEGLSPRTIDVSAEVTVTPSGGGLTITGIDITLRA
                     AVDGVDEQKFQELAGTAKETCPVSRALAGTTINLDASLSD"
     gene            complement(21727..22419)
                     /locus_tag="FCN18_RS31410"
                     /old_locus_tag="FCN18_31405"
     CDS             complement(21727..22419)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1239: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020642130.1"
                     /locus_tag="FCN18_RS31410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_31405"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_137096776.1"
                     /transl_table=11
                     /translation="MPAHRTARERARAELTAAIKDEARRQLGEQGADGLSLRAVARELG
                     MVSSALYRYFPSRDDLLTALIIDAYNALGATLEKAAAGADAPRERWRAACHGLRAWGLA
                     NRHEYSLIYGTPIPGYRAPQDTVTPATRVPAVFIGALRDAWRAGEVKPPFKGPEMSPEL
                     RRQVGIVRAQLAPDVPEEVLARGLIAWVQLFGMVGFELGGQFANTVDPADEFFTHTVEQ
                     MTLFVGLG"
     gene            22544..22999
                     /locus_tag="FCN18_RS31415"
                     /old_locus_tag="FCN18_31410"
     CDS             22544..22999
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0070967 - coenzyme F420 binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005167113.1"
                     /locus_tag="FCN18_RS31415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_31410"
                     /product="nitroreductase family deazaflavin-dependent
                     oxidoreductase"
                     /protein_id="WP_112265161.1"
                     /transl_table=11
                     /translation="MATQYDENRYLRPKAPTNLFNSAVQLLTRLGVSLWGSRVLYVRGR
                     KSGELRSTPVNLLTFEGERYLVAPRGHTQWVRNLRVAGEAELRVGRRVEMIKPVELSDD
                     EKPPVIHAYLKKWAWETGAFFEDITAKTPQDELRRVAPGFPVFRIPA"
     misc_feature    22802..22804
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(23112..23321)
                     /locus_tag="FCN18_RS31420"
                     /old_locus_tag="FCN18_31415"
     CDS             complement(23112..23321)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009156702.1"
                     /locus_tag="FCN18_RS31420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_31415"
                     /product="formate dehydrogenase subunit delta"
                     /protein_id="WP_199542779.1"
                     /transl_table=11
                     /translation="MTSTISPQVRMANDIAVQFRHLPVDEAAKAIANHIRMFWDPRMKS
                     ELRRLVDEDPTSFDPVALTAAKQV"
     gene            complement(23334..26144)
                     /gene="fdhF"
                     /locus_tag="FCN18_RS31425"
                     /old_locus_tag="FCN18_31420"
     CDS             complement(23334..26144)
                     /EC_number="1.17.1.9"
                     /GO_component="GO:0009326 - formate dehydrogenase complex
                     [Evidence IEA]"
                     /GO_function="GO:0008863 - formate dehydrogenase (NAD+)
                     activity [Evidence IEA]"
                     /GO_process="GO:0015942 - formate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="fdhF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer2_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1134: flavodoxin"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009156701.1"
                     /locus_tag="FCN18_RS31425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_31420"
                     /product="formate dehydrogenase subunit alpha"
                     /protein_id="WP_137096777.1"
                     /sec_met_domain="Fer2_4 (E-value: 2.8e-26, bitscore: 84.1,
                     seeds: 114, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGLLKEHDFGTPAKPGPATVTVEIDGVPVTVPEGTSIMRAAAETG
                     TDVPKLCATDSLEAFGSCRLCLVEIDGKKGTPASCTTPVAEGMKVRTQTPKLEKLRQGV
                     MELYISDHPLDCLTCAANGDCELQDMSGVVGLRQVRYGYEGENHLDAPKDTSNPYFDFD
                     ASKCIVCSRCVRACGEVQGTFALTIEGRGFDSKVSPGAAELFMDSECVSCGACVQACPT
                     ATLQEKSVVDLGMPTRTVLTTCAYCGVGCSFKAELRGDELVRMVPYKDGGANEGHSCVK
                     GRFAFGYATHPDRKLNPMIREKITDEWREVDWETAISYVAEKFRDIQARHGAGSIGGIT
                     SSRCTNEEVYVVQKMVRAAFGNNNVDTCARVCHSPTGYGLKQTFGTSAGTQDFRSVAQA
                     DVIVVIGANPTDGHPVFASRMKRRLREGAKLIVIDPRRIDLVRSPYIEAEHHLQLAPGT
                     NVAIVNAMAHVVVTEGLVDRSFVADRCEEFDEWAAFIAREENSPEATESITGVPAEQVR
                     AAARLYGGAGNGAIYYGLGVTEHSQGSTMVMGMANLAMATGNIGREGVGVNPLRGQNNV
                     QGSCDMGSFPHELSGYRHVSDDAVREVFEKLWERPILPEPGLRIPNMFDAAVDGTFLGL
                     FVQGEDIAQSDPNTQHVNAALSAMELVVVQDLFLNETAKFAHVFLPGTSFLEKDGTFTN
                     AERRINRVRPVMAPKTGKDEWRVACEIAQAMGYAMNYEHPREIMAEIAAVTPTFAGVSF
                     EKLDKLGSVQWPCNDKAPEGTPTMHVDAFVRGKGRFVQTPFVATRERSTRKYPLILTTG
                     RILSQYNVGAQTRRTANVAWHPEDVLEIHPHDAEVRGIENGDEVTLSSRVGTTTLRALI
                     ADRMPVGVVYTTFHHPVTGANVVTTENSDWATNCPEYKVTAVQVGLKHAVDRHDAARDE
                     EPALAD"
     gene            complement(26148..27698)
                     /locus_tag="FCN18_RS31430"
                     /old_locus_tag="FCN18_31425"
     CDS             complement(26148..27698)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020670408.1"
                     /locus_tag="FCN18_RS31430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_31425"
                     /product="NADH-quinone oxidoreductase subunit NuoF"
                     /protein_id="WP_112265157.1"
                     /transl_table=11
                     /translation="MITVYVPRDSAAVSVGANEVAAAIQREAGAEPVRIVRNGSRGMLW
                     LEPFVEVETDRGRVGYGPVTPEAVPGLVEAGLFEGAPHELCQGVVDELSWMRDQQRLCF
                     ARVGVTDPLSTEDYEANGGLAGLRRALELDPADVVAQVTESGLRGRGGAGFPAGIKWNT
                     VRGTEGPLKFVCCNADEGDSGTFADRMLMEGDPFCLIEGMTIAAHAVGASEGYIYIRSE
                     YPDAVNTMRRAIDIAYAHGWLGENVLGSGLKFDLFVRVGAGAYICGEETSMLESLEGKR
                     GMVRSKPPIPAITGLFGKPTVVNNVLTLASVPTILADGPQAYADLGVERSRGTQVFQLA
                     GNIARGGVFETAFGITLGELVNGYGGGTRSGRPVRAAQVGGPLGSYVPTSQFELPMDYE
                     AFAAADAMLGHGGVVVFDDTVDMAAMARFAMEFCAEESCGKCTPCRVGAVRGVEVIDKI
                     TGGEDRDGNLALLNDLCELMTDGSLCAMGGLTPNPVRSALTHFPDDFMTNNARHEEAK"
     gene            complement(27695..28189)
                     /locus_tag="FCN18_RS31435"
                     /old_locus_tag="FCN18_31430"
     CDS             complement(27695..28189)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020670409.1"
                     /locus_tag="FCN18_RS31435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_31430"
                     /product="NAD(P)H-dependent oxidoreductase subunit E"
                     /protein_id="WP_112265155.1"
                     /transl_table=11
                     /translation="MAVDSAGTSVVERVRAVIDAHKGERGALLPILHGIQAEFGYIAPE
                     VVPVLANELNMSRADVHGVITFYSDFQAEPSGTTTVRLCRAEACQSVGAERLVADAEQV
                     FGVKVGQTTPDGSVTLGQVFCLGNCALGPAAQINGRMYGLMDRARLVELLVRAEGGEET
                     A"
     misc_feature    28202..28220
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 26.62"
                     /tool="antismash"
     misc_feature    complement(28206..28224)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 25.92"
                     /tool="antismash"
     gene            complement(28301..29080)
                     /locus_tag="FCN18_RS31440"
                     /old_locus_tag="FCN18_31435"
     CDS             complement(28301..29080)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1195: IclR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:TIGR02431.1"
                     /locus_tag="FCN18_RS31440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_31435"
                     /product="IclR family transcriptional regulator C-terminal
                     domain-containing protein"
                     /protein_id="WP_137096778.1"
                     /transl_table=11
                     /translation="MKSPDEKDYVQSLERGLSVILAFSDRRPRLTLGELSELTGLSRPT
                     VRRLVLTLERLGYVRTEGRQYVLTPHVLALGNAYLSSLNLTEVAQPYMEDVTKVTGHTC
                     SLAALDGEDAVFLTRVPSRRVMRHTLTTGTRLPAFATSMGRVLLAWLPGHEIEEFLHHA
                     PFPRITARTVTDPDRLREILREVRTQGWALVDQEFEEGVRSFSAPVLDSGGRAIASLSM
                     SVPAGELSVADIEAETLPVIVEAAREISKQLGAPDRG"
     gene            complement(29077..30195)
                     /locus_tag="FCN18_RS31445"
                     /old_locus_tag="FCN18_31440"
     CDS             complement(29077..30195)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1268: mandelate racemase/muconate lactonizing enzyme"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013673018.1"
                     /locus_tag="FCN18_RS31445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_31440"
                     /product="muconate cycloisomerase family protein"
                     /protein_id="WP_113642252.1"
                     /transl_table=11
                     /translation="MGELSIASVRTVVVDLPLRRPHKFKSMSATRQSYLVVRLRTEGGA
                     EGVGEAVVPGGPWWGGESVESMKVMVDEYLAPQLVGAEVSRVDYLMDRLDRVAARNSFA
                     KAALEMAIFDAWGRTLGVPVYQLLGGLYRESIPVTWALGAEESEVVFAEAEEKLSSGLH
                     ASFKLKMGALDPAADTARVASVARALGDKASVRVDLNAAWDEPTSARWLPVLEEAGVDL
                     VEQPVPGWNVDAMRRLAARLTIPVMADESLLTPHDALRLVGEEAADIFSLKVHKHGGLS
                     ATRRVAAVAEAAGLPCHGGSSIESSIGTAAAAHAYAAIRGVTFGCELFGPLLLAEDLVT
                     DPLTYADGALRVPSGPGLGVTIDEEKLGRFAR"
     gene            complement(30195..30974)
                     /locus_tag="FCN18_RS31450"
                     /old_locus_tag="FCN18_31445"
     CDS             complement(30195..30974)
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0018576 - catechol 1,2-dioxygenase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009712 - catechol-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012976.5"
                     /locus_tag="FCN18_RS31450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_31445"
                     /product="dioxygenase"
                     /protein_id="WP_137096779.1"
                     /transl_table=11
                     /translation="MTTTAAVNPTQQRTAEVVADIFGVINERLVRHSVTYPEYQAAKAW
                     LIKVGEAGEWPLLLDVFFEHTIEKLASERRQGSSGCIEGPYYVPGAPELSSPATLPQRP
                     DEPGDVLVFTGTVRDLDGNPLPGSVVDIWQADALGYYSQFHPDPPQWNLRANVTTGADG
                     RFEITTVVPAPYEIPKEGPTGQLIRAAGWHHWRPAHLHMMVRAQGCRTLTSQLFFAGGE
                     YVDEDIASAVKPELTLELAHLGDGRYAAEYDFTLDPA"
     CDS             complement(30977..>31373)
                     /codon_start=3
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010242343.1"
                     /locus_tag="FCN18_RS31455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_31450"
                     /product="4-hydroxyphenylacetate 3-hydroxylase C-terminal
                     domain-containing protein"
                     /protein_id="WP_323808384.1"
                     /transl_table=11
                     /translation="YPRVREIIMQDLGSGLIYLPSHAMDFRSPEIRPYLDQYVRGSNGM
                     EAVERVKLMKLIWDSIGSEFGGRHELYERNYSGNHEGVRAELLFAAQQSGAADAMKGFA
                     EQCMAEYDLDGWTAPDLVNPDDVSLRRR"
     gene            complement(30977..>31377)
                     /locus_tag="FCN18_RS31455"
                     /old_locus_tag="FCN18_31450"
ORIGIN
        1 ggcaggccct gctacaccct cgctccgaag gcgccgacga gcagcaagca cgtgctctac
       61 ttccacggcg gcgcctacgt ccaccagatc cagaaggacc actggtcgtt cttcgagcgg
      121 ctcatcaagc gcaccggctg cactgtcacg gtgccgatct acccgctcgc gccggaccac
      181 aagtccgacg agaccgttcg catgatcaag gacgcctaca acgagctgct cggcgacacc
      241 gaccccggtg atcaggtgat catgggtgat tcggcgggcg gcgcgctcgc actcgtgctc
      301 tcggaggcgc tggaggaggc gcacgagccg cagccgaagg agctcgtgct gatctgcccg
      361 tggctcgaca tcaccatgac cgatcccgcg ctgcccgagc tcgaccgcat cgatccctac
      421 cttgccgtcg ccgggctgcg cgaggccggc cgcctctacg cgggcgatct cgacaagcgc
      481 gatccgctcg tgagtccgct gttcggaccg ctgtccagcc tcggccgcgt cagcgtcttc
      541 gtcggtaccc gtgacgtgct gctggtcgat gcgcggcgcc tccgtgatcg cgcgcgggac
      601 gagggcgtcg gactggagta ccacgagtac cccggcatgt tccacgcctg gctgctcgcc
      661 gacatccccg aggggcgcga cgcgctggag cgcatcgcta cggtggtcag ccgcgtgcgc
      721 gagttccccc acgagacccg cgagtccccc gcctgagccc gcgagtcccc cgctccgaca
      781 cgcgagttgc ccgttcggtc ccgcgagtcc cccgctcggt cccgcgagtc ccccgctccg
      841 acacgcgagt cccccgctcg gtcccgcgag tcccccgctc gggccggcga gttgcccgtt
      901 cggggcgagc gggagcgcac aactcggcgt cctgagcgca caactcggtg tcctgagcgg
      961 gggactcggt gtcctgagcg ggggactcgc gggctggagc gggggactcg cgggccgcgt
     1021 cagtgccggg ttgattccct ggtcaccagt tcgggtttga acatgacctg ctggtgggcg
     1081 tgggtgtccg ggttgtcgca ctcctccacg agcagctgcg cggccgcccg gccgatctgc
     1141 tgcgtcggct ggcggatgga cgtgagcgga acagccgcgt cggcggcgaa ctcgatgtcg
     1201 tcgtagccga cgatcgcaag gtcacccggt actcgcctgc ccgtggacag tgcggcgcgc
     1261 agcacgccga gcgccatgag gtcgttggcg cagaacgccg ccgtcgcccg ctcgccctgc
     1321 tcgaaccggg cacgggcgac gtcgtgggtg ctgcgcgcgt tcatcaccgg gatctccacc
     1381 acctcgatca cggcgtccgg gtcgaggccg gccgccgcga cggaccgccg caggccggtg
     1441 aggcggtcgg cgcactggct cagcccgagc ggcccggaga agtacacgat ccgctcgtgc
     1501 ccctgcgcca ccagatgcgc gcctgccagc tctccgccca cgacgtcgtc cacggccacc
     1561 gagcagcagt tgaccctcgg gtcgtgccgg tcgacgagca ccgtgggcgt tcctcgtctg
     1621 cgcagcgcgt cgagccggtc ggagctgacc tcgatcggcg tgatcagcac cccgcgcacc
     1681 cgctgctcct ccagcacctg gaggtaccgg ttctcgcggg aggtctggtc gtcggagttg
     1741 cacagcacca cggcgtagcc cagctcgtcg gcgacctgct ccaccccgcg ggccacgtcg
     1801 tggaagaacg ggttggccat gtcgagcacg atgagtccga tcgaacggct ggtgcccgcc
     1861 cgtagctgtg ccgcggagga gttgcggacg aagccgagcg ccgcgatcgc cgactgcacc
     1921 gcggtcctgg tggactcggc gacgcgctcg gggtggttca ggacgttgga cacggtgccg
     1981 accgagacgc ccgcgcgcac cgcgacgtcc ttgatgctcg gcgacatcgg cgacataccc
     2041 tgcctcgctc tgtgctgaaa cgttcaaccg aaaggttgca caccagggat tctgcgatca
     2101 gaagcaagct aacacgagct gccgcgaggg ggcctgccgg atcgttatca aacggcacgt
     2161 caagcggggt cttgacgacg cgcccggaac ggcctaactt gagcgccact cgtgaatgaa
     2221 acgtttcacg atctccaccg aaggaggaca tcgtggcagc accggaacac accggcgtgc
     2281 cgctactcga gctccgcgac gtcaccaagt cgtttcaggc ggtccgcgcc ctgcgcggcg
     2341 tctccctcgc gctccgtgcc ggggaggtgc acgcgctggc gggcgagaac ggcgcgggca
     2401 agtcgaccgt cgtccggatc atcggcggcg agcaccagcc cgacagcggc gaggtcctcc
     2461 tcgacgggga gcccgtgcgt ttctcctcgc cgcgcgaggc acagcagcgc ggcgtcgcag
     2521 tcatccacca ggaacccatc cagttccccg acctctccgt cgccgagaac gtgttcatgg
     2581 gccgccagcc gctgcgccct ggccgccgca tcgaccgcag ggccatgcac cgcagggcct
     2641 ccgaggtgtt cgagcagctc ggcgtgccga tcgacccggc gcggcagacc cggggcctct
     2701 ccatcgccga ccagcagatc atcgagatcg ccaaggcgct ggtcgccgac gcgcggatca
     2761 tcgtgatgga cgagccgacg gccgcactgt ccgctgtgga ggccgagcgg ttgttccgcg
     2821 tcgcgcgcgg actcgccgaa cgcggcgcgg cgctgctgtt catctcccac cgcctcgacg
     2881 agatgtacgc actgtgcgac cgggtcaccg tgcttcgcga cggctcgttc gtcgtcaccg
     2941 agcggatgga cgacatcgac aacgacacgc tcgtgcgccg catggtgggc cggtcggtgg
     3001 agcagctctt ccccaagcgc gacaccgagg tgggcgacga ggtgctggtg gtcgacggcc
     3061 tcacgcgggc cggtgtctac cgggacatct ccttctccgt gcgccgcggc gagatcgtcg
     3121 gactggccgg gctggtcggc tcgggccggt ccgaagtggt cagagccgtc ttcggcgtgg
     3181 acgaccggga ctcgggaacc gtgacggtga acgggaaacc actgccgaag agcaagccgc
     3241 gcaccgcgat cgagcagggc atcgcgctgg tgccggagga ccgcagggag caggggctcg
     3301 tgctcgagct gtccatcgag cgcaacgcga gcctcgcgcg gctgaagcag gtctcgccgg
     3361 gcgggctcac ccgccagtcg agggaacgcg agctcgcacg cacgtggggc gagcggctct
     3421 cgctgaagtt cggcagcctc tccgaccccg ccgccacgct ctccggcggc aaccagcaga
     3481 aggtcgtgct cggcaagtgg cttgccaccg agccgtcggt gctgatcgtc gacgagccga
     3541 cgcgcggcat cgacatcggc gccaaggtcg aggtccacgc gctgctgtcc gacctcgccg
     3601 ccgagggcat ggcggtgctg ctgatctcct ccgagctgcc ggaggtgctc ggcatggccg
     3661 accgcgtgct cgtgatgcac gagggccgga tcaccgccga gctgtcccgc gacgaggcca
     3721 ccgaggagtc cgtcatgtac gccgcgacag gcaacgggag tgccgcatga gccgacttcg
     3781 cgcgctgctc tccgggcgtg agctgagcat cgtcgtcgcg ctcgtcgccg tggtgggtgt
     3841 gaccacagcg accaacccgt ccttcctgag cgcgcagggc atccacgacc tgttcctcaa
     3901 cgcgtcgatc atcgcgctgc tcgccatcgg ccagacgctc ctggtgatca cgcgcaacat
     3961 cgacctctcc gtgggctcgg tgatgggcct gaccgcctac atgtcgggcc agatgttcat
     4021 cgccgaccac gacacgccaa cgatcctcgt ggtgctcgcg ggcatggcac tcggcgcggc
     4081 gtgcggcgcg ttcaacgggg cgctcgtggc catcgcgaag gtgcccgcgc tcgtggtgac
     4141 gctgggaacg ctgtacgtct tccgcggcat caactacggc tgggcgagcg ccacgggcgt
     4201 gcaccagatc aacgccgacc agatgtcgca gggcttcctc gcgttcggca gcggttcgat
     4261 actgggcatc ccacacctca cgctgatcgc gctggccgca ctggtgatcg ccgcgtacgc
     4321 gctgcacaac tggcgctccg gccgcgagct gtacgcgatc ggctccaacc cgcaggcggc
     4381 gcgccttgcc ggtatccccg ctggcaagcg ggtgttcacg gcgttcgtcg tgtccggagc
     4441 gctcgtcggg ctcgcgggcg tgctgcacgc gtcgtacttc ggcacgatca atgcctcggt
     4501 cggcaccggc cgcgagctcg ccgtggtcgc ggccgtggtg gtgggcgggg tcgccatctt
     4561 cggcggcagc gggacggtgc tcggcgccgt gctcggtgcg ctgctgctga ccacgatcac
     4621 gagcgcgctg cccatcctcg gcgtgcccgc cttctggcag cgcgccgtcg acggcgccgc
     4681 gctgctgctc gcgatctcgc tggaccgggc ggtgatggtg cgactagccg agcgcctccg
     4741 gaaggaaagg agcctgcgcc gtgcgtgaga aactgctccg ctgggagtcg gtcctcctgc
     4801 tgttgtgcat cttcgtgttc gtgtggggct cggcgagcac gcccggcttc gccgagaccg
     4861 acaacatcag cttcctgctg ctggactaca ccgaggtcgc gctgctcgcg ctggcgctgc
     4921 tgccgatcat cctcaccggc gagatcgacc tttcggtggc gtcgatcctc ggcttctgct
     4981 ccgccctcac gggtgtgctg tgggacgcgg ggatgtcgtt cgagtcgatc gtgccgatcg
     5041 tgctcgtcgc gggcgcggtg ctcggctcgc tcaacgcgac gctgatcgtg aggttcgccc
     5101 tgcccgcgct cgcggtcacc atcggcacgc tcggcctcta ccgggggctc gcgtacgtgg
     5161 tgctcggcga cggcgcggtc acgggctttc ccgacgtcta ccgtccgatc gcgacggagg
     5221 agatccccgg cacgttcctg ccgtacgcga cgctggtggt gctgctgctc ggcgtgctcg
     5281 tcgccgtggt cgtgcactac acaccggttg gccgctcgct gtatgcgatc gggctcggcg
     5341 agcagacggc gcggttctcc ggaattcgcg tgcagcgcat caagttcgtg ctctacatcg
     5401 tgtcgggcat cctgtgcgcg atcgcctcgc tcgtctacac gttgcgctac aacagcgccc
     5461 gcgccgacaa cgccaacggc atggagttga tcgcggtcgc ggccgtgctg ctcggcgggg
     5521 tgtcgatctt cggcggccgg ggcacggtcg tcggcgtcgc gagcgccctg ctgctgatgg
     5581 ccgggctgcg caacgtgctg ttcctcaacg acgtgaccaa cgagatccag aacgtgatca
     5641 acggcctgct gctgatcatc tcggttctgg ttcccgtggt cgcgaacctg gtgcgcaggc
     5701 ggcgtacacc ggccgcggcg gcgataccgg gatcaccacc accgcaggaa accctgccag
     5761 accccgtggg ggcgaccgcc gccccgcacg gcacccccga ggaggaccaa agatgatcca
     5821 ccaccgatgg agcgggaagc gggcgttgct cgcggtgacc agcatgggcc tcgcggccgc
     5881 gctggtggcc ggctgtggcg gcacgaccaa ggacagcgcc gagtccggca gcggatccgg
     5941 cgcgaactcc gagaaggtcg ccgacccgaa cgccccgatc aaggaggggc tgcagatcgc
     6001 cttcctgccg aaggagatcg acaaccccta cgagaacatc gtcgaccagg gtggcatcgc
     6061 ggcggtcgcc gagctcaagg gcaccggcaa ggaggtcggc ccctcggacg cctccgcgtc
     6121 gtcgcaggtc tcctacatca acacgctggt gcagcagaac caggacgcga tcgtgatcgc
     6181 ggccaacgac cccaacgccg tcgctcccgc gctcaaggac gcgatggcga agggcatcgc
     6241 ggtcgtcagc tacgactccg acgccgcggt ggacgcgcgc caggtgttcg tcaaccaggc
     6301 cgactccgag tcgatcggcc gttcccagat ccagatggtg tccgagcaga tcggcggcaa
     6361 gggcaagatc gcgatcctgt ccgcgacccc gaacgcgacg aaccagaaca cctggatcga
     6421 gttcatgaag gacgagctga agaagccgga gtacaaggac atcgagctgg tcaccgtcgc
     6481 atacggggac gacgacgacc agaagtcctt ccaggagacg caggcactgc tgtcctccaa
     6541 cccggacctg aaggcgatcg tctcgccgac caccgtcggc atctcggccg ccgcgcgcta
     6601 catctcgtcg tcgccgtaca agggcaaagt ggtgctcacc ggtctcggca ccccgaacca
     6661 gatgcgccag ttcatcaagg acggcacggt gaaggagttc gcgctgtggg acccggagca
     6721 gctcggatac ctcgcgggct acgccgcagc cgcgctggcc tccggccaga tcaccggcaa
     6781 ggaaggtgag gtcctcaagg cgggcaagct cggcgagcgc aagatcggca agaacgggga
     6841 gatcatcctc ggcccgccga ccacgttcaa cgccgacaac atcgacgagt acgacttctg
     6901 atggccaccg gacctcggcg tgtctgcttc ctgctcaggg tgaagccgga ccgcatggac
     6961 gagtaccggc gcagacacgc cgaggtctgg ccagagatgc gggcggcgtt gcgggagacc
     7021 ggctggggca actactcgct gttcctcgcc ccggacggtc tgctcgtcgg ctacttcgag
     7081 accgacgacc tcgacgccgc actcgaaggc atggcagcaa aggaagtcaa cgccaggtgg
     7141 caggccgaga tggccgagtt cttcgagaac ctcgacggcg cgcccgacga aggcatcgtg
     7201 ccgctgcccg aggtcttcca tctcgactga tccacaccac aagagggagg gctccatgtc
     7261 cgactactcc gccgtcaaag ccgcgctgcg tgagcagcgc atcgagaccc cctcgtgggc
     7321 cttcggcaac tccggcacgc ggttcaaggt gttcgcgcag gaggggatcc cgcgcgacgc
     7381 ctacgagaag atcgcggacg ctgcgaccgt gcaccggttc accggtgtcg cgccgagcgt
     7441 cgcggtgcac atcccttggg acagggtcga cgactacgcc gacctcgcca agcacgcgga
     7501 gaacctgggc gtgcgcatcg gcgccgtcaa ccccaacgtg ttccaggacg acgactaccg
     7561 gctcggcagt gtctgcaacc cggacccggc cgtgcggaag aaggcgctcg ggcacctgct
     7621 cgactgcgtc gacatcatgg acgtgacggg ttcgcgggac ctgtcgatct ggctggcgga
     7681 cgggctcaac tacccgggcc aggactccat cgccgaccgg caggcgcggc tggaggaggc
     7741 gctcgccgcg gtgtacgagc ggctgggcga gaaccagcgg atgctgctgg agtacaagtt
     7801 cttcgagccc gcgttctacg ccaccgacgt gcccgactgg ggcaccagct acgcgcactg
     7861 cctcgagctc ggcgagaagg cgcaggtgct cgtggacacc gggcaccacg cgcccggcac
     7921 caacatcgag ttcatcgtgg cgttcctgct gcgcaagcgc aggctcggcg gtttccactt
     7981 caactcgcgg ttctacgccg acgacgatct gatggtgggc gccgccgacc cgtaccagct
     8041 gttccggatc atggtcgaga tcgtgctggg cggtgggctc gacgcggcat cgggcgtcgc
     8101 gttcatgctc gaccagtgcc acaacatcga gccgaaggtc cccgcgctga tccgctcggt
     8161 gctgaacgtc caggaggcca cggcgaaggc cctgctcgtg gacgccgacg cgttgcggaa
     8221 ggcgcagcag gccggggatg tgctgggcgc caacgggatt ctcaccgacg ccttcgccac
     8281 ggacgtccgc ccgctgctcg gggagctgcg cgaggagatg ggcctcgacc cggatccgat
     8341 gtccgcgtac aagcgcagcg gctacgcgga gcggatcgtc gccgagcgcg tgggcggcac
     8401 cgccgccgga tggggagcgt gacatgacca accaggccgt caccgatctg ctcgcgcgct
     8461 cgcacgcgct cggcgccgac cggcgcaaca ccaactacgc gggcggcaac gcctccgcga
     8521 agggcaccga cctggacccg gcgaccaacg ccgaggtgga gctgatgtgg gtcaagggct
     8581 ccggtggcga cctcggcacc ctgaaggaga ccggcctcgc ggtactgcgg ctcgaccgca
     8641 tgcgtgcgct cgtggacgtc tacccgggcg aggagcgcga ggacgagatg gtcgccgcgt
     8701 tcgactactg cctgcacggt aagggcggcg ctgccccgag catcgacacc gcgatgcacg
     8761 gcctcgtcga cgcggcgcac gtggaccacc tgcaccccga ctccggaatc gccatcgcca
     8821 ccgcggtgga cggcgaggag ctgacccgca aggtgttcgg cgaccgcgtc gtgtgggtgc
     8881 cgtggcggcg gcccgggttc cagctgggcc tcgacatcgc ggcgatcaag caggcaaacc
     8941 cgcaggccat cggttgcgtc ctcggcgggc acggcatcac ggcgtggggc gacacgagcg
     9001 agcagtgcca ggcgcactcg ctggagatca tccgcaccgc ggaggcgtac ctcgccgagc
     9061 acggcgaccc cgagccgttc ggcaaggcgc tgcccggcta cgagccgctt cccgaagaag
     9121 agcggcgagc ccgcgcggca ctgttgttcc ccgtgctgcg cgggctcgcg tccaccgact
     9181 cgcctcagct ggggcacttc accgacagcc ccgaagtgct cgagttcctc gcccacgaga
     9241 agcaccccgc gctcgcggcg ctcggcacgt cgtgcccgga ccacttcctg cgcaccaagg
     9301 tcgcaccgct cgtggtggac ctccccggca gcgcgccgat cgacgatgtg ctcgaccgga
     9361 tcagggagct gcacgcggcc taccgcgagg actacgccgc ctactaccgg cggcacgcga
     9421 cgccggactc gccgccgatg cggggcgccg acccggcgat cgtgctggtg cccggcgtcg
     9481 gcatgttcag cttcgggcgc gacaagcaga ccgcgcgcgt ggcgggcgag ttctacgtca
     9541 acgcgatcaa cgtgatgcgc ggcgcagagt cggtgtcgac gtacgcgccg atcccggagt
     9601 cggagaagtt ccgcatcgag tactgggagc tggaggaggc caagctgcgg cggatgccga
     9661 agccgaagcc gctcgcgacc aggatcgccc tcgtgaccgg cggcggctcc ggcatcggca
     9721 gggcgatcgc gcaccggctc gccgccgagg gcgcgtgcgt ggccgtggcc gaccgcgacc
     9781 tctcctcggc gaccgaggtg gccgaggaga tcggcaacac cgaccgggcc gtggccgtgg
     9841 ccgtggacgt caccgacgag gacggcatcg ccgcggcggt ggctgccacg tcactcgcgt
     9901 tcggcggcgt ggacctggtg gtgaacaacg ccgggctgtc cgtgtcgaag ccgctgctgg
     9961 agaccagcgc gaaggactgg gacctccagc acgacgtgat ggcgcgcggc tcgttcctcg
    10021 tgtcgcgcga ggcggcgcgc gtgatggtgg cgcagggcct tggcggcgac atcgtctaca
    10081 tcgtcagcaa gaacggggtc ttcgcgggcc ccaacaacat cgcctacggc gcgacgaagg
    10141 ccgatcaggc gcatcaggtg cggctgctgg cggcggagct cggcgagcac ggcatccgcg
    10201 tcaacggtgt caaccccgac ggcgtggtgc gcggctccgg catcttcgcg tccggctggg
    10261 gcgcgcagcg cgcggccgtg tacggggtgc cggaggagga gctgggtgcc ttctacgcga
    10321 agcggaccct gctcaaacgg gaggtgctgc ccgagcacgt cgcgggcgcg gtgttcgtgc
    10381 tgaccgcggg cgacctctcc cacaccaccg gcctgcacat cccggtcgac gccggtgtcg
    10441 cagccgcgtt cctgaggtga ggttgatgca gtgaaggcca ccatgcctgc gttggacgca
    10501 gtgaaggtgg ccttcactgc ggggtgggcg ttccgtggtg ggccttgatg cagtgaaggc
    10561 caccatgcct gcgttgaacg cagtgaaggt ggccttcact gcatcggcgg accggctttt
    10621 cttgacagag gaggctccat gagcgacacg aagcggcggc cccggatcgg gctggtcgcg
    10681 ggcgggctgg gtgcctactg gccgcagttc cccgacctgt tgccgacgct gaagcagtcg
    10741 tcggcgtacg tgagcgagcg catcaccggc ttcgatgctg agatcgtgga cgtcgggttc
    10801 atctccgacg cacaggaggg cgccgccgcg gccgagaagc tgcgcgcggc gggctgtgac
    10861 ctcatcgtcg ggttcctcac gacgtacatg acggccacga tgctcatgcc gatcgcgcag
    10921 cgcagcggcg ctccggtgct gctgatcaac ctgcagccca ccgagtcgat ggatcacgcc
    10981 accttcgaca ccgggcagtg gctcgcctac tgcggcgcgt gcccgctgcc ggagatggcg
    11041 aacgcgttcc gccgcgcggg cgtggagttc cgcagcgtgt ccgggcacct gcgcgacgag
    11101 cgtgcgtggg ccaagatcgg gcgctggatc tccgctgccg ccgtgcgcaa ggtgctgcgc
    11161 cacggcaggc acgggctcat ggggcatctc taccccggca tgtacgacgt ctccaccgac
    11221 ctgaccatgg tcaacgccca cttcggcggg cacgtcgagg tgctggagtt cgacgacctg
    11281 cgcgtgcgcg tcgagcaggt caccgacgcc gacgtggccg caaaggtcgc cgaggccgag
    11341 tcggtcttcg agctggacgc gtcggttaac cgcgaggacc tcgaatgggg cgcgaaggtg
    11401 gccgtgggcc tcgatcggct cgtcgccgac ttcgatctcg acagcctcgc ctactaccac
    11461 cgcggcctcg atggggagac ccacgagcgg ctcggcgccg ggatgatcct cggcgcgagc
    11521 ctgctcaccg cgcgcggcgt cccggccgcc ggggagtacg agctgcgcac gagcatcgcg
    11581 atgttgatca tggacgtgct cggcgcgggc gggtcgttca cggagctgca ggcgctcgac
    11641 ttcgagcgcg ggcacgtcga gatgggccac gacggccccg cgcacctggc gatcagcgcg
    11701 aagaagcccc tgctgcgcgg gctcggcgtc taccacggca agcgcggctg gggcgtgtcc
    11761 gtcgagttcg acgtcgcgca cggcccggtg acgctgtgcg ggatcggcca ggaccgcgag
    11821 ggccggtact cgctgatcgt gtcggagggc gaggtggtgg acgggccgct catgcgcatc
    11881 ggcaacacca cgagccgcgt cgacttcggg cgcgaccccg gcgaatggac cgacgagtgg
    11941 tccgccagcg gcgtcgccca ccactgggcg ctcggtgtcg ggcaccgggc cgccgagctg
    12001 cgcgccgtgg cgagcctgct gggcgttccg ctggtcgagg taggccggtg accgctttcg
    12061 tcgccgtcga cctcggcgcc acgagcgggc gggtcatgct cggccaggtg atcgagggga
    12121 ccatcgacct cacggagctg cgccgcttcc gcaccgggcc ccgtgagcgg cccggcggcg
    12181 ggctgcgctg ggacgtcgag gagatgtacg ccgagatcgt cgcgggtctg cgcgaggccg
    12241 agggcgcgga gccggtgtcg atcggcatcg actcgtgggc cgtcgactac ggcctgctcg
    12301 acgcggacgg caggctcgac ggcgatgtgc gctgctaccg cgacccgcgt accgacggca
    12361 tggcggcgcg gcttcgtgag cgggtcgacg acgagacgtt gtaccgcatc acgggcctgc
    12421 agtacctgcc gttcaacacg atctaccagc tgctcgccga gccggaggag cggctggccg
    12481 gcaagacgat gctgctgctg cccgacctca tcggctaccg gctgaccggc gagttcggcg
    12541 ccgaggtgac caacgcgtcc accacggcgc tgctcgacgc caccacgcgc cagtggtcca
    12601 cggaactcgc ggacaaggtg ggcctgcccg ccgggctgct gcccccgttg cgccagcccg
    12661 gcgagccgat cggcaccgcc cccggcgggg tgccggtggt ggccgtggcc tcgcacgaca
    12721 cggcctcggc cgtggccgcc gtgcccgctc tcggcgaccg gttcggctac gtctcgtgcg
    12781 gcacgtggtc gctcgccggg ctcgaactgc ccgcgcccgt gctcaccgac gaggcccgca
    12841 gggccaactt caccaacgag gccggcatcg acggcacggt gcggttcctg cgcaacacca
    12901 tgggcctgtg gctgctcacc gagtcgctac gcgtttggcg ggagcggggg cacgacatta
    12961 ggctcgacga cgtgctgaag gcggcgatgc gggaaccggc tttcaggtcc attgtggacg
    13021 ctgatcaccc ggttttcctg accccgggtg acgtgcccgc gcgcatcgcg acgctgtgcc
    13081 gcgagtcggg gcagccggtg ccggagaccc cgcccgccgt cgtgcgcacg atcctggagt
    13141 cgctggcgct cgcgcatgcc gactcgctgc ggacggccgc gcggctcgcc gaccgcgagc
    13201 tcgacgtcgt gcacttggtc ggtggcgggg cactcaacga gccgctctgc cagttgaccg
    13261 ccgacgcgtg cggcctgccg gtgctcgcgg gcccggtgga ggcgagcgcg ctcggcaacg
    13321 tgttcgtgca ggcaagggct gccggagtgc tcgcggacgt gccgtcgagc gcgccgctgg
    13381 cccgctacga gccgcgggga gagcaggcgg cgtggcgcac ggcggccgag cgggcggggc
    13441 tgggatgagc gcgccgcgcg tggcgctgtt cgccacctgc ctcaccgaca cgctctaccc
    13501 ggagaccggc aaggccgtgg tccggctgtt gacgcggctc ggctgcgacg tcgacttccc
    13561 gctcgcgcag acgtgctgcg gccagatgca ctacaacacc ggctaccacg accacgcccg
    13621 cccgctcgct cgcgactacg cggcgacgtt cgagggctac gaccacgtgg tggcgccgtc
    13681 aggctcgtgc ggcgcgatgg tgcgggagat ccacccgagc ctgtgcggca cgagccccgc
    13741 cgtggagcgc acctacgagc tgagcgagtt cctcgtcgac gtgctcggcg tgaccgacgt
    13801 cggcgcgtac ttcccgcacc gcgtcaccta ccacccgacg tgccactcgc tgcggatgct
    13861 cggcgtcggc gacaagccgc tcagcctgct gcgcgcggtg aaggggctgg agctggttga
    13921 gctgccgcag gccgagcagt gctgcggctt cggcggcacg ttcgcgctca agaacgcgga
    13981 gacgtccacg gcgatgctgg ccgacaagat gcgctgcgtg caggacaccg gcgcgcaggt
    14041 gctcagcgcc ggtgacaact catgcctcat gcacatcggc ggcgggctgt cgcggctgcg
    14101 cacgggcgtg cggacggtgc acctggcgga gatcctggcg agcacggagg aggagccatg
    14161 ggcgtccgca acccggtgac ctggctgggg agcccggtgt tccccaaggc cgcgcacgag
    14221 gcgctcgcgg acacgcagct gcgccgcaac ctgcgcaagg ccaccaccac catccgcacc
    14281 aagcgcgcgg gcgtcgtggc cgaactggac gactgggagc ggttgcgtca ggcgggcgag
    14341 gccatcaagg acgacgtgct cgccaacctc gacacgtacc tggtgcggct ggagaaggcc
    14401 gtcaccgcgc gcggcggcgt cgtgcactgg gctcgcgacg cggaggaggc caatcggatc
    14461 gtgctcgacc tcgtgcgtgc ggagggcgcc gacgaggtcg tgaaggtcaa gtccatggcc
    14521 accgccgaga tcggactcaa cgaggcgctg gaggcgggcg gcgtgcgcgc ggtggagacc
    14581 gatctcgccg agctgatcgt gcagctcggc gacgaccggc cctcccacat cctcgtgccc
    14641 gcgatccacc gcaaccgcgc ggagatccgc gacgtcttcc gcaggggcat ggccgaggag
    14701 cccgcctcag acgagccgcg cgacctcgcc gaggcggccc gcaggcacct gcggcgaaag
    14761 ttcctgtcgg ccaaggtcgc catctccggg gccaatttcg cggtcgccga caccggttcg
    14821 atcgtggtgg tggaatccga gggcaacggg cgcatgtgcc tgaccctgcc ggaaacgctg
    14881 atcaccgtaa tgggcatcga gaagctcgtg ccgagctggc aggacctgga ggtgttcctg
    14941 cagctgctgc cgcgatcgtc cacagcggaa cggatgaacc cctacacctc ggtgtggtcg
    15001 ggcgtgacgc cgggcgacgg gccgaggagg ttccacctgg tgctgctgga caacgggcgc
    15061 acggccacgc tcgccgacca ggtggggcgg caggcgctgc ggtgcatccg ctgttcggca
    15121 tgcctcaacg tgtgcccggt gtacgagcgc acgggcgggc aggcgtacgg ctcggtgtac
    15181 ccgggtccga tcggcgcgat cctcgccccg cagctcgccg gggacatgca tgacgagcag
    15241 gcggcgtcgc tgccgtacgc gtcgtcgctg tgcggcgcgt gctacgaggt gtgtcccgtg
    15301 cggatcaaca tccccgaggt gctcacccac ctgcgtgcgg aagccgtgcg ggcaaaggga
    15361 aagcgcaccc cggaggcgat cgcgatggcc gccgcggcgt gggtgttcgc cgacccgaag
    15421 cgatacgagg cggcgcagaa ggcgggctcg ctctcgcggc tgctcgcccg cgacgggcgc
    15481 atcaaacggc tgccggggcc cggtgcgaag tggacggact cgcgcgacgc gcccgcggtg
    15541 ccgaaggagt cgttccgcgc gtggtggagg aagaaccatg ttcagcgctc gtgacgagat
    15601 cctggcccgc atccgtgccg tgaaccgcgc gtcgccggtg ccgatcccga gggactacga
    15661 gcgcacgcgc acggtgcccg acgtgctggg actgctggac gagcgggtca ccgactacaa
    15721 ggcgatcgtg caccgcgtcg ccgaggcaca gctgccggac aggatcgccg accgcctcgc
    15781 gctccgttcc gtgtcgacga tggcggtgcc ctccgacgtg ccgccggagt ggcgcgtccc
    15841 ggcggtgacg tggctgcccg acgagccgcc gcttccgctc gccgaactgg acactgtgga
    15901 cggtgtgctg acgggctgcg cggtggcgat cgccgagacg ggcacgatcg tgctcgacgc
    15961 gggtgcgggg cagggtcgcc ggatgctcag cctggtgccc gactaccacc tgtgcgtggt
    16021 gcgagccgac caggtggtga cgagcgtgcc ggaggcgctg gcgcggctgg agccgggacg
    16081 cccgctgacg ttcatcagcg gaccgtcggc gacgagcgac atcgagctgg accgggtgga
    16141 gggcgtgcac ggcccccgca ccctggaggt cctgatcgcc acctgaccag ccgaccgcag
    16201 tgaaggccac cttcactgcg ttcaatgcag tgaaggtggc cttcactgca ttgaggcgag
    16261 cctccgcgga ccctcgtgct gaccgtcagc tgatcgagcc cggcggcgcg agccgcgcca
    16321 cgggctggcc ggtgacctcg gcgatctgct cgaagtcgtg gtcgtggtgc accagcgtga
    16381 ggccggccag ctcggcggtc gccgcgagca gcaggtccac ggcaccggcc gagcggtggg
    16441 tgcccgcggc cgtcagcgcg tcctgcacct cgaaggcgcg tcggaagacc tcgtcgggaa
    16501 ccgggagcca cgtgaacgcc gcgccgatca gctccacgag ctggtcgcgg tccgccttcg
    16561 atcgagccgt gtgcaggaac tccagctcga ccaggggaca cgtcgccacc agccccgcct
    16621 cgatctgctg ctcccagccc gcccgcgccc gcgcgtcgcg cagcacgcgc accagcgcgc
    16681 tcgtgtcgaa caggtagcgg actgcgatca ccgccggtag gactccttgt cgagcagctc
    16741 gtcaaacgcc ccggactcgc ccagctcggc cagcctggcc agcgccttgg cacggcggat
    16801 gcgctgcgtg gtctccctca aggcggtgtt gaccgtgtcc ttcttcgtct tggtgcccag
    16861 gagcctcgag gcttcggcca gtgcctcgtc gtcgatgtcg atcagtacct tcgccacgaa
    16921 cgcctcccgg tatatacggt gacgtcactc agtatatacg cctacccggc catcctgggg
    16981 aacagctccc cggcgctcac cggcctgccg aagcggtagc cctgcgcctg gtcgcagttc
    17041 agctcccgca gcacctcgag ctgccgatcg gtctccacgc cctccgcgat cacggtgagc
    17101 cccatgctgt gcgccatcgt cacgatgccc ctgatgatcg cctcggcctc ggacttgccc
    17161 ggccgtccga tcccggcgac gaacgactgg tcgatcttga gcgtgtccag cggcagccgc
    17221 cagagctggg ccagcgagga gtagccggtg ccgaagtcgt cgatcgcgag ccgcacaccc
    17281 agccctcgca gcgccgacag cgccccgccc gccacctccg ggtccctcat gagcgcgctt
    17341 tccgtgatct ccaggcacag cgtctgcggc ggcagcccgg tgcggcgaag agcctcctcc
    17401 acggtcggca ccagcgcggc gtcgtcgagc tgccgggcgg agaggttgac cgtcagccgg
    17461 gtgtcgaggt tccgcgcggc acgctggctc gcgatctcct cggtcgtggt cctgagcatg
    17521 tagtcgccga tgaggttgat caggtcgctc tcctcggcga gcgggatgaa ctcgacgggc
    17581 gagatcgcgc cgtgcgtcgg gtggtgccag cgcatgaggc cctcgacggc cacggtccgg
    17641 cacgtccgca ggtccaccac cggctggtag gccatccaca gctggccgtc caccacggct
    17701 tcgcgcagat cctgctccag ccgcagctgc cgctggacgc gttcccgcag ctcgacgtcg
    17761 aagaactcgt accgcccgcg accccgcgtc ttggcctcgt acatcgccac gtcggcgtca
    17821 cggatgagat cctcggccga gcgcgcgtcg ccgggcgccg cggtgacgat gccgacgctc
    17881 gcgtccacgc gcagctgcct gccgtcgagg ccgatcggct tggtcagcga ggcccgcagg
    17941 tgcccgatga gcgagcggat gccggtgtcg ccggagacgt cgaaggtcac cacggcgaac
    18001 tcgtccccgc cgagcctgcc gaccaggtcg gtcgcgcgca cacagtggcg caggcgctgg
    18061 ccgacgacgc ggagcacctg gtcgccggtg ctgtgcccga gcgagtcgtt gatcagcttg
    18121 aacttgtcga ggtcgatgaa caacacgcac gcgaggccct cgcggtccgg ctcggccagc
    18181 gcgccgtcca gccgctgcag cacgagggtc cggttggcga ggcccgtgag cgggtcgtgc
    18241 gtggcgtcgt gctccagctg ctcgccgatg gccctgcgtt cggtgatgtc ggtgaacgac
    18301 gtgacgaccg tcgatggggg cgcggcgtcg ggatcgagcg gccggcagct catggacagc
    18361 cacacgtagg tgccgtcggg tcgttgcagc cgcagtacgc gcccgttctg cgcctgccct
    18421 gtcgccagta cctcggagaa cgggtactcc gtcgcggcga gccgggcccc cgactcgccg
    18481 tacagcggga acctcgtcgg tgacgacttc ctcagcaccg tgttcggcat gccgaggatc
    18541 ctggccgccg ccgggttggc cgactcgatc atcccgtcgg ggccgatcac cacgacgccc
    18601 tcgtcgagcg cggcgaccac cgtgctgtac cgccgctcgg cccgccgccg gggcgtctcg
    18661 tcggcgcaca cgagcacgta gccgtcgtgc atctcggccg cggagacccg gatggccagt
    18721 gtcgagccgt ccgccgtgcg gtggtcgccc tcgacgacgc cgcccgccgc catcacccgc
    18781 tccgggtcga gcggcgcgcc gacgagctcg ccgacgtccc tgccgatggc ctcggtgctg
    18841 gaccgcccgt acacggcctc cgcggcggga ttccagctgg tcacgatgcc gtcggcagtg
    18901 gtggcgatga tcgcgtcgct gacgtgggag acgagcgccg cctggtagtg cagtgccgcc
    18961 tcggcggcct tctgcgccgt gatgtcgcgc atgatgacct ggaacgcggg cctgccctgc
    19021 cacgtcgtgc gcaccgacac cgactcgacg agcatcgagt cgccgtcgaa gcgcttgagc
    19081 tgcacctcgg tgggctccga ggtggcgccc ggggtggtca ggccctcgat gcggtgcagc
    19141 atcgcgggga ccgaggcggg gtcgacgaag tcggtgatgg gcctgcccag cagctcgtcg
    19201 gccgagtcca ccgcggcgaa ccgcagtgcc gccgggttga cgtagacgag tttgccgccc
    19261 tcgtgaacgc agatcgcgtc agggctgagc tcgaccagca gccggtaccg gtcggccagg
    19321 tcggcgagcg cctgctcgct gccatgccgt tcagtcacgt ccgtagcaat cccgagaagt
    19381 ccggccttgg tgccgccggg tcgaggtcgg gccaggaacc ggatccatct gacctcgcct
    19441 tccggcgtct cgaggctctg ctcaagctcg aaattatccc acggcggagc attccgcagc
    19501 gtcacgtcga tcggtgagat caattccagg agcgtgcgcc ggatgtcggc ttcggcctcc
    19561 tcggggagcc cgaacatcgc gccaagccct gccgaccacg taacgcggcc gtcgccggcg
    19621 ccgacggacc acctggccga cgagccggcg gcgagcgcca ggtcagcgac tatctcgtgg
    19681 tcagggtcgg tgccggtggt cacctctgcg tgggtccgcg cctccatgtc ccgtccatcc
    19741 gcgtggtgct gggaaccccg attagagcac ggtttcgccg ctaggcgaac aggaggattc
    19801 ggcggcgact tcgcgttagc ggcatcccgg gcgcggcctt tcgtcgtcaa aacagtaggc
    19861 ggactttttt tggactgtgc agtgcgaagc cgcctatccg ccaaacgaaa ggtgagaaag
    19921 tgagtaagga caaggacgtg tcgcgtggaa tcgaaatatg cggcatcggt gcggtcaccg
    19981 gttatggctg gggccgcgaa atgctgtggg acggcctggt ttccggcaag tccgcggccg
    20041 tgctgaccgg cggtttcggc cggaaccggg acgagtccgc ctgggtcgcc gcggtgcccg
    20101 aaggcggtga tcccgccgac ggccgtggtc gctttgctcg tgccatgcgc gcttccgcac
    20161 gcgaggcgat cgaggacgcg aagggccgcg ggtggactcc gggcaggcgg gtcggtctgc
    20221 tgcacgccgt cgtgatcgga gaggcgtatc tgtggaagga cttctacgtc accgacaagg
    20281 gaaaactgcg actgcgggat tacctggcgc tcatgccgtc cactccgatg tcgacgttca
    20341 tgcaggagta cggattccac gggcccgcca tgaacgtgtc ggcgatgtgt gcctcgggaa
    20401 acgcgggact gctcacggcg aaggcgtggc tcgacgcggg gatcgtggac gacgtcgtgc
    20461 tcgtcgccac ggatctgtcg ctcacgccgg agaacgtgct gcatttcact cggctcggcg
    20521 tcgcggtggc caaccgggag ccactcgacg gctgtcgtcc cttccaggag ggcagccgcg
    20581 gtttcgtgat gggtgaggcg tcggtcggga tggtgctttc gaaccgctcc gacaagccgt
    20641 atgcggtcac cctcggcggt gccatgtccc acgacgcgta ccacgtgacg tcgatcgacc
    20701 cggagtttcc cgaggtgcgg cgctgtttcg tggaggcgct cgacaacgcg cgggtgccgg
    20761 cggaggaagt ccgctacgtc aacgcgcacg gccccggcac gaagcagtgc gacagggtcg
    20821 aggccgcgat cgtggaggag atgttccgtc cggacaccgg gatctactcg gtgaagccgc
    20881 tggccgggca ctgccagggc gcggcgtcgg cggtcgaggt cgcggtggcg gcgatcggct
    20941 atgaacgcgg cgtgatccct gctccaccga gcgtggccga ggcgcatccg cagctgctgc
    21001 acggtgagtt cggtgtggac ggcgggctga ccgtgaagtc gtcgctgggc atgggcggcc
    21061 acaactccgt ggtcgtgctc ggtccggctc gcgcgtgacc gaagccggtg accggcatac
    21121 tgctcgatgc cggtcaccgg cctcgcgatg tctgtgaagt ggcttgcgtg gcggagccga
    21181 tgggcggttc aggcgcgagg cggctccgcc ggttccgagt cgcagctaat cgctgagcga
    21241 ggcgtcgagg ttgatcgtgg tgcccgcgag ggccctgctc accgggcacg tttccttggc
    21301 cgtaccggcg agctcctgga acttctgctc gtcgacgccg tcgaccgcgg cgcgcaacgt
    21361 gatgtcgatg ccggtgatgg tgagcccgcc cccggagggt gtcaccgtca cctcggcgct
    21421 gacgtcgatc gtcctgggcg agaggccctc cttctccagg acgccggcaa gattcatcgc
    21481 gaggcacgac gactgtgccg ccgcgatcag ctcctcggga ctggtcgtgc cctcgggctc
    21541 gccgatccgg cgcgggaacg tgacctcgaa ctgcccgctg ttggacgagt cgagcgtcac
    21601 ggtgcccttg cccgagttga gtccgccggt ccaatgcgtg gtggagtcgc ggctggccat
    21661 gtcggctccc ttcgtggcgt tgctgctggt cccctcgacc ataggccggt tcggcgctga
    21721 ggccgcctat ccgagcccca cgaacagcgt catctgctca acggtgtggg tgaagaactc
    21781 gtcggcgggg tcgaccgtgt tcgcgaactg cccacccagt tcgaagccga ccatgccgaa
    21841 caactggacc cacgcgatga gcccccgcgc gaggacctcc tccggcacgt cgggcgccag
    21901 ttgcgcgcgg acgatgccca cctgcctgcg cagctcgggg gacatttccg gacccttgaa
    21961 gggcggcttg acctcgccgg cacgccacgc gtcgcggagg gcgccgatga acacggcagg
    22021 cacgcgcgtg gcgggcgtga cggtgtcctg gggagcccgg tagccgggga tcggtgtgcc
    22081 gtagatcagg gagtactcgt gccggttggc aagtccccac gcgcgcagac catggcacgc
    22141 ggcgcgccag cgctcgcgcg gtgcgtcggc gcccgcggcg gccttctcca gagtcgcgcc
    22201 cagcgcgttg taggcgtcga tgatcagcgc ggtgagcagg tcgtcacggc tggggaagta
    22261 gcggtacaga gctgaggaca ccatgccgag ctccctggcg accgcgcgca gggaaaggcc
    22321 gtcggcgccc tgttccccga gctgtctgcg ggcctcgtcc ttgatcgcgg ccgtcagctc
    22381 cgcacgggct cgttctctcg cggtccggtg ggctggcatg ccgctcagtg tgccattggc
    22441 gagatcggtg cacaaattcg agagcaccgc tcttgactcc tcgtggacca aggtgttcac
    22501 tgatctcaac agagagcacc gctctcgaac tgaaggagac atcatggcga cccagtacga
    22561 cgagaaccgc tacctccgcc ccaaggcccc caccaacctg ttcaacagcg ccgtccagct
    22621 gctgacccgg ctcggcgtga gcctctgggg cagcagggtg ctctacgtcc gcggccgcaa
    22681 gagcggcgag ttgcggtcga cgccggtgaa cctgctgacg ttcgagggcg agcgttacct
    22741 cgtcgcgccg agggggcaca cgcagtgggt gcgcaacctg cgcgtcgcgg gtgaggccga
    22801 gttacgcgtg ggcagacgcg tggagatgat caagccggtc gagctgtccg acgacgagaa
    22861 gccgcccgtg atccacgcgt acctgaagaa gtgggcctgg gagacgggcg ccttcttcga
    22921 ggacatcacc gcgaagaccc cgcaggacga gctgcgccgc gtcgccccgg gcttcccggt
    22981 gttccgcatc cccgcctgac gcgcaggtga cccgcgccgc tgtcgcgaac ggagccccac
    23041 ccacccccgc caaacgagag caagggagct ttgctctcgt ttgacgggag taaagctccc
    23101 ttgctccccg atcagacctg cttggcggcg gtgagggcta ccgggtcgaa ggaggtgggg
    23161 tcctcatcga ccaggcggcg tagttccgac ttcatcctcg ggtcccagaa catccggatg
    23221 tggttggcga tcgccttcgc cgcctcgtcg accggcaggt gccggaactg cacggcgatg
    23281 tcgttggcca tccgcacctg aggcgagatc gtgctcgtca tgtcgctcct cgactagtcc
    23341 gccagcgccg gttcctcgtc gcgggccgcg tcgtgccggt ccaccgcgtg cttgaggccc
    23401 acctgcaccg cagtcacctt gtactcgggg cagttcgtcg cccagtcgga gttctcggtg
    23461 gtcaccacgt tcgccccggt cacggggtgg tggaacgtcg tgtacacgac ccccacgggc
    23521 atccggtcgg cgatcagcgc gcgcagcgtc gtggtgccca cccggctgga aagcgtcacc
    23581 tcgtcgccgt tctcgatgcc cctcacctcg gcgtcgtgcg ggtggatctc cagcacgtcc
    23641 tccgggtgcc acgcgacgtt ggcggtgcgc cgcgtctgcg cgcccacgtt gtactgcgac
    23701 aggatgcggc cggtggtgag gatcagcggg tacttgcgcg tgctgcgttc ccgcgtcgcc
    23761 acgaacggcg tctgcacgaa ccggcccttg ccgcgcacga aggcgtcgac atgcatcgtc
    23821 ggcgtgccct ccggggcctt gtcgttgcac ggccactgca cgctgccgag cttgtcgagc
    23881 ttctcgaacg agacaccagc gaaggtcggc gtcaccgccg cgatctccgc catgatctcg
    23941 cgcgggtgct cgtagttcat ggcgtagccc atcgcctgcg cgatctcgca cgccacgcgc
    24001 cactcgtcct tgcccgtctt cggcgccatc accgggcgca cgcggttgat gcgccgctcg
    24061 gcgttggtga acgtgccgtc cttctccagg aacgacgtgc ccggcaggaa gacgtgcgcg
    24121 aacttcgccg tctcgttgag gaacaggtcc tgcaccacca ccagctccat cgctgaaagg
    24181 gcggcgttga cgtgctgggt gttcgggtcg gactgcgcga tgtcctcacc ctgcacgaac
    24241 aggccgagga acgtgccgtc cacggcggcg tcgaacatgt tcgggatccg caggcccggc
    24301 tccgggagga tcgggcgctc ccacagcttc tcgaacacct cgcgcacggc gtcgtcggac
    24361 acgtgccggt agcccgacag ctcgtgcggg aacgagccca tgtcgcacga gccctgcacg
    24421 ttgttctgcc cgcgcagcgg gttcaccccc actccctcgc ggccgatgtt gcccgtggcc
    24481 atcgcgaggt tcgccatgcc catcaccatc gtggagccct ggctgtgctc ggtgacgccg
    24541 aggccgtagt agatcgcgcc gttgcccgcg cctccgtaaa gccgtgccgc cgcgcgcacc
    24601 tgctccgcgg gcacgccggt gatcgactcg gtggcctcgg ggctgttctc ctcacgggcg
    24661 atgaacgcgg cccactcgtc gaactcctcg cagcggtcgg ccacgaacga ccggtcgacg
    24721 aggccctcgg tgaccacgac gtgcgccatc gcgttgacga tcgcgacgtt ggtgccgggt
    24781 gcgagctgga ggtggtgctc cgcctcgatg tacggcgagc gcacgaggtc gatccgcctc
    24841 gggtctatga cgatcagctt ggcgccctcg cgcagcctgc gcttcatgcg cgaggcgaac
    24901 acggggtgcc cgtcggtcgg gttcgcgccg atcaccacga tcacgtcggc ctgtgcgacc
    24961 gagcggaagt cctgcgtgcc cgccgaggtg ccgaacgtct gcttgaggcc gtagccggtg
    25021 ggcgagtggc agacccgggc gcacgtgtcg acgttgttgt tgccgaacgc cgcgcgcacc
    25081 atcttctgca ccacgtagac ctcttcgttg gtgcagcgcg acgacgtgat gccgccgatg
    25141 gaaccggcgc cgtggcgggc ctggatgtcg cggaacttct cggcgacgta cgagatcgcg
    25201 gtctcccagt cgacctcgcg ccactcgtcg gtgatcttct cgcggatcat cgggttgagc
    25261 ttgcggtcgg ggtgggtcgc gtagccgaaa gcgaaccggc ccttgacgca cgagtggccc
    25321 tcgttggcgc cgccgtcctt gtacggcacc atgcgcacga gctcgtcgcc acgcagctcg
    25381 gccttgaacg agcagccgac gccgcagtag gcgcacgtgg tgagcacggt ccgcgtcggc
    25441 atgccgaggt ccacgacgga cttctcctgc agcgtcgcgg tcgggcacgc ctgcacgcac
    25501 gcgccacacg agacgcattc ggagtccatg aacagctcgg cggcgcccgg cgacaccttg
    25561 gagtcgaagc cgcggccctc gatcgtcagg gcgaacgtcc cctgcacctc gccgcaggcc
    25621 cgcacgcacc gcgagcacac gatgcacttg gacgcgtcga agtcgaagta cgggttgctg
    25681 gtgtccttgg gcgcgtcgag gtggttctcg ccctcgtagc cgtagcgcac ctgccgcagc
    25741 ccgacgacgc cggacatgtc ctgcagctcg cagtcgccgt tggcggcgca cgtgaggcag
    25801 tcgagcgggt ggtcggagat gtagagctcc atcacgccct gccgcagctt ttccagcttc
    25861 ggcgtctgcg tgcgcacctt cataccctcg gccacgggcg tggtgcacga ggccggggtg
    25921 cccttcttgc cgtcgatctc cacgagacac agccggcagg agccgaacgc ctcgaggctg
    25981 tcggtggcgc acagcttcgg gacgtccgtc ccggtctccg ccgccgcgcg catgatcgac
    26041 gtgccctccg gcacggtcac tggcacgccg tcgatctcga cggtcacggt cgccggtccc
    26101 ggcttggccg gggtgccgaa gtcgtgttcc ttcaacagac ccatggtcta cttcgcctcc
    26161 tcgtggcggg cgttgttcgt catgaagtcg tcgggaaaat gggtcagcgc actgcgcacc
    26221 gggttggggg tcagcccgcc catcgcgcac agcgacccgt cggtcatcag ctcgcagagg
    26281 tcgttcagca gcgcgaggtt gccgtcccgg tcctcgccgc ccgtgatctt gtcgatcacc
    26341 tcgacgccgc gcacggcgcc gacgcgacac ggcgtgcact tgccgcacga ctcctcggca
    26401 cagaactcca tcgcgaaccg tgccatcgcc gccatgtcca cggtgtcgtc gaacaccacc
    26461 accccgccgt ggcccagcat cgcgtccgcg gccgcgaacg cctcgtagtc catcggcagc
    26521 tcgaactgcg aggtcggcac gtacgagccg agcgggccgc cgacctgcgc ggcccgcacc
    26581 gggcggccgg aacgcgtgcc gccgccgtag ccgttgacga gctcgccgag cgtgatgccg
    26641 aacgcggtct cgaacacccc gccgcgcgcg atgttgcccg ccagctggaa cacctgcgtg
    26701 ccacgggagc gttcgacgcc gaggtcggca tacgcctgcg ggccgtcggc gaggatcgtc
    26761 ggcacactgg cgagggtcag cacgttgttc accacggtcg gcttgccgaa cagcccggtg
    26821 atcgcgggga tcggcggctt cgagcggacc atgccgcgct tgccctcgag gctctccagc
    26881 atggaggtct cctcgccgca gatgtaggcg cccgcgccca cgcgcacgaa gaggtcgaac
    26941 ttcagcccgg agccgagcac gttctcaccg agccagccgt gcgcgtaggc gatgtcgatg
    27001 gccctgcgca tcgtgttcac ggcgtccggg tactccgagc ggatgtagat gtagccctcg
    27061 ctcgcgccca ccgcgtgcgc ggcgatggtc atgccctcga tgaggcagaa cgggtcgccc
    27121 tccatgagca tccggtcggc gaacgtgccg ctgtcgccct cgtcggcgtt gcagcacacg
    27181 aacttcagcg ggccctcggt gccgcgcacc gtgttccact tgatgcccgc ggggaacccc
    27241 gcgccgccgc ggccgcgcag gcccgactcg gtcacctgtg cgaccacgtc cgcggggtcg
    27301 agctccagtg ctctgcgcag cccagcgagc ccgccgttcg cctcgtagtc ctctgtggat
    27361 agtgggtcgg tgacgccgac cctggcgaag cacaggcgct gctggtcgcg catccacgac
    27421 agctcgtcga cgacgccctg gcacagctcg tgcggcgcgc cctcgaacag cccggcctcg
    27481 acgagaccgg gcacggcctc aggcgtcacc ggcccgtagc cgacgcggcc ccggtcggtc
    27541 tccacctcca cgaacggttc gagccagagc atgccgcgcg agccgttgcg cacgatccgg
    27601 acgggttcgg cgcccgcctc gcgctggatc gcggcggcga cctcgttggc gcccaccgag
    27661 acggctgccg agtccctcgg cacgtagacg gtgatcatgc ggtctcctcg ccaccttccg
    27721 cgcgtaccag cagctccacc aggcgcgccc ggtccatgag cccgtacatc cggccgttga
    27781 tctgggccgc ggggccgagg gcgcagttgc cgaggcagaa gacctgcccg agcgtcaccg
    27841 agccgtccgg cgtcgtctgc cccaccttca cgccgaacac ctgctcggcg tccgccacga
    27901 ggcgctccgc acccaccgac tggcaggcct ccgcgcggca cagtcgcacc gtcgtggtgc
    27961 ccgagggctc ggcctggaag tcggagtaga aggtgatcac gccgtgcacg tcggcgcggc
    28021 tcatgttcag ctcgttcgcc agcaccggaa ccacttccgg ggcgatgtag ccgaactcgg
    28081 cctggatgcc gtgcaggatc gggagcaggg ctcctcgctc gcccttgtgc gcgtcgatca
    28141 cggctcgaac gcgttccacg accgacgtac cggcgctgtc caccgccata ccgcaacctc
    28201 cttgatgtat acggtataca tcgtcgatcg tacccgcgcg gtgacgtaga caacaagggt
    28261 acgttccgcc gggcgggtgt ggaacgcacc gaatcgctcg tcagcccctg tccggggcgc
    28321 cgagctgctt gctgatctcc cgcgcggcct cgacgatcac gggcagcgtc tccgcctcga
    28381 tgtcggccac gctcagctcc cctgcgggca ccgacatgct cagcgacgcg atggcgcggc
    28441 cccccgagtc gagcaccggc gcggagaacg agcgcacacc ctcctcgaac tcctggtcca
    28501 ccagcgccca gccctgcgtg cgcacctccc gcaggatctc gcgcagccgg tccgggtcgg
    28561 tcaccgtccg cgcggtgatc ctcggaaacg gcgcgtggtg caggaactcc tcgatctcgt
    28621 gtccgggcag ccaggccagc agcacgcggc ccatcgacgt cgcgaacgcg ggcagccgcg
    28681 tacccgtggt gagcgtgtgc cgcatgacgc ggcgggaggg cacacgggtc aggaacaccg
    28741 cgtcctcgcc gtcgagcgca gccagcgagc acgtgtgccc cgtgaccttg gtgacgtcct
    28801 ccatgtaggg ctgggccacc tcggtcaggt tgagcgaaga caggtaggcg ttgcccagtg
    28861 cgaggacgtg cggcgtgagc acgtactgcc tgccctcggt gcggacgtag cccagccgct
    28921 ccagcgtgag cacgaggcgc cgcacggtcg ggcgggaaag gccggtcagc tcggaaagct
    28981 cgccgagggt cagcctgggg cggcggtccg agaaggcgag gatcactgag agaccgcgtt
    29041 cgagcgactg gacgtagtcc ttctcgtcgg gcgacttcat cgggcgaacc tgcccagttt
    29101 ctcctcgtcg atcgtcacgc cgagacccgg cccgctcggc acgcgcaacg cgccgtcggc
    29161 gtacgtcagc gggtcggtga ccaggtcctc ggcgagcaac aacgggccga acagctcaca
    29221 gccgaacgtg acgcccctga tggccgcgta ggcgtgtgcc gccgcggcgg tgccgatgga
    29281 actctcgatg ctcgacccgc cgtggcaggg caggcccgcc gcctccgcga ccgcggcgac
    29341 cctcctcgtc gccgacagac cgccgtgctt gtgcaccttc agcgagaaga tgtccgccgc
    29401 ctcctcgccg accagccgca gggcgtcgtg cggggtcagc aggctctcgt cggccatcac
    29461 cgggatcgtt agccgcgcgg cgagcctgcg catcgcgtcg acgttccagc ccggcaccgg
    29521 ctgctcgacc aggtcgacgc cggcctcctc cagcacgggc agccaacgag ccgacgtcgg
    29581 ctcgtcccac gccgcgttga ggtcgacgcg cacgctggcc ttgtcgccga gcgccctggc
    29641 caccgaggcg acgcgcgcgg tgtccgcggc agggtcgagc gcgcccatct tgagcttgaa
    29701 cgacgcgtgc aggcccgagg agagcttctc ctcggcctcg gcgaacacca cctccgactc
    29761 ctcggcgccg agcgcccacg tcacgggaat cgactcgcgg tacagcccgc cgagcagctg
    29821 gtacaccggc acgccgagcg tcctgcccca cgcgtcgaag atcgccatct ccagcgccgc
    29881 cttggcgaag gagttccgcg cggccacgcg gtcgagccgg tccatcaggt agtccacgcg
    29941 cgacacttcg gcgccgacga gctgcggggc gaggtactcg tcgaccatca ccttcatcga
    30001 ctcgacactc tccccgcccc accacggtcc gccgggcacc acggcctcgc cgaccccctc
    30061 ggcgccgccc tcggtgcgca gccgcaccac caggtagctc tgcctggtcg cactcatcga
    30121 cttgaacttg tgcggccggc gcagcggcag gtcgaccacc accgtgcgga ccgaagcgat
    30181 ggacagctct cccatcacgc gggatccagt gtgaagtcgt actcggccgc gtagcgcccg
    30241 tcgccgaggt gggccagctc cagcgtgagc tccggcttca cggcgctcgc gatgtcctcg
    30301 tcgacgtact cgccgcccgc gaagaacagc tggctcgtca gcgtccggca accctgcgcg
    30361 cgcaccatca tgtgcaggtg tgcgggccgc cagtggtgcc agcccgcggc cctgatcagc
    30421 tgaccggtcg gaccttcctt cgggatctcg tacggcgccg ggacaaccgt cgtgatctcg
    30481 aaccggccgt ccgcgccggt ggtgacgttc gcgcggaggt tccactgtgg agggtcgggg
    30541 tggaactgcg agtagtagcc gagcgcgtcg gcctgccaga tgtccaccac cgagccgggg
    30601 agcgggttgc cgtcgaggtc gcggacggtt ccggtgaaca ccagcacgtc gcccggctcg
    30661 tccggccgct gcgggagcgt ggccggtgag gacagctcgg gcgcgcccgg gacgtagtac
    30721 gggccctcga tgcacccgga gctgccctgg cgccgctcgg aggcgagctt ctcgatcgtg
    30781 tgctcgaaga acacgtcgag caacagcggc cactcgccgg cctcgccgac cttgatcaac
    30841 cacgccttgg ccgcctggta ctcggggtag gtcaccgagt gccgcaccag ccgctcgttg
    30901 atcacgccga agatgtcggc cactacctcc gccgtgcgct gctgggtggg gttcaccgct
    30961 gcggtcgttg tcatgactac ctcctccgga ggctgacgtc gtcgggattg acgaggtctg
    31021 gggcggtcca gccgtcgagg tcgtactcgg ccatgcactg ctcggcgaag cccttcatgg
    31081 cgtcggccgc gccggactgc tgggcggcga agagcagttc ggcgcgcacg ccctcgtggt
    31141 tgccggagta gttgcgctcg tagagctcgt ggcggccgcc gaactcactg ccgatcgagt
    31201 cccagatcag cttcatcagc ttcacgcgct cgacggcctc catgccgttg gagccgcgca
    31261 cgtactggtc gagatacggg cggatctccg gggaccggaa gtccatggcg tgcgagggca
    31321 ggtagatcag cccgctgccg aggtcctgca tgatgatctc gcgcacgcgc gggtagc
//
