LOCUS       NZ_SWMS01000023        24104 bp    DNA     linear   CON 10-DEC-2024
DEFINITION  Prauserella endophytica strain CGMCC 4.7182 Scaffold23, whole genome
            shotgun sequence.
ACCESSION   NZ_SWMS01000023
VERSION     NZ_SWMS01000023.1
KEYWORDS    WGS; RefSeq.
SOURCE      Prauserella endophytica
  ORGANISM  Prauserella endophytica
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Prauserella; Prauserella
            coralliicola group.
REFERENCE   1  (bases 1 to 105665)
  AUTHORS   Liu,J.M., Habden,X., Guo,L., Tuo,L., Jiang,Z.K., Liu,S.W., Liu,X.F.,
            Chen,L., Li,R.F., Zhang,Y.Q. and Sun,C.H.
  TITLE     Prauserella endophytica sp. nov., an endophytic actinobacterium
            isolated from Tamarix taklamakanensis
  JOURNAL   Antonie Van Leeuwenhoek 107 (6), 1401-1409 (2015)
   PUBMED   25832628
REFERENCE   2  (bases 1 to 105665)
  AUTHORS   Li,Q.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-APR-2019) Yunnan Institute of Microbiology, Yunnan
            University, No. 2 Cuihu North Rd, Kunming, Yunnan 650091, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 10.16x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_005146945.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 16:32:08
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,852
            CDSs (total)                      :: 7,795
            Genes (coding)                    :: 7,703
            CDSs (with protein)               :: 7,703
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 34 of 92
            Pseudo Genes (incomplete)         :: 69 of 92
            Pseudo Genes (internal stop)      :: 2 of 92
            Pseudo Genes (multiple problems)  :: 13 of 92
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 18:09:25
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 39494
            Orig. end                         :: 63598
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            SWMS01000023.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24104
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="triceptide"
                     /region_number="1"
                     /rules="((cds(PF04055 and (TIGR04085 or SPASM)) and
                     triceptide_precursor) or triceptide_rSAM)"
                     /tool="antismash"
     cand_cluster    1..24104
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((cds(PF04055 and (TIGR04085 or SPASM))
                     and triceptide_precursor) or triceptide_rSAM)"
                     /kind="single"
                     /product="triceptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24104
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14104](-)"
                     /cutoff="5000"
                     /detection_rule="((cds(PF04055 and (TIGR04085 or SPASM))
                     and triceptide_precursor) or triceptide_rSAM)"
                     /neighbourhood="10000"
                     /product="triceptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..14104)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="((cds(PF04055 and (TIGR04085 or SPASM))
                     and triceptide_precursor) or triceptide_rSAM)"
                     /neighbourhood="10000"
                     /product="triceptide"
                     /protocluster_number="1"
     misc_feature    148..162
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 21.73"
                     /tool="antismash"
     gene            757..1632
                     /locus_tag="FCN18_RS30125"
                     /old_locus_tag="FCN18_30120"
     CDS             757..1632
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012707.5"
                     /locus_tag="FCN18_RS30125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_30120"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_110343883.1"
                     /transl_table=11
                     /translation="MAKRSPRLKTLMAAALSLALVSTSCGTNSGAVGSNNSAGLPTTLV
                     VATGDYKVPTSFLNKKGELDGLNVDLTRALGRRLGVEMKLVAVPFDAVIPGIQSGRFDT
                     ALFNVSDTPERRAVVDLVDYAPSGTVIVTRKNDRKGITANPLTLCGRTVAVKAGQTEFN
                     ILNKDVSPKCKETGEPAINFQTFKDDNGLEFAVETGRADAFLGGTTVTPYFVSRNSDTF
                     EIVGKLPIALDPLGMPFAKGRDDLVGAVLAAWKEIWQSGEYERIAKKWSLQSIVPKDIS
                     LFTVNGGDKS"
     gene            1629..2579
                     /locus_tag="FCN18_RS30130"
                     /old_locus_tag="FCN18_30125"
     CDS             1629..2579
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013678583.1"
                     /locus_tag="FCN18_RS30130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_30125"
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_110343884.1"
                     /transl_table=11
                     /translation="MTSLTESRETSLDRDRATAEDFEVKPGLHIVRWVVAGVVLLFAAQ
                     LVYGAATNPRLSWDIVADYFFDPQILDGLLVTLGLTMVSQVLATVIGLTVALMALSHNP
                     VLVAVARIYVAVFRTVPTMVQMLFWYYLAAVVPVLSIGIPFGPDLVTLDTNSVMTQFAA
                     ALLGLALGEAAFLAEYFRGGIISVPRGQIDAAAACGLTPACTFRRIVLPQALRVILPAY
                     GNAMIINIKNTSLVFVIGAGDLMTRAQLIYSQNFQQIPLLIVVSGWYMVIVLLLTWLQR
                     RIEVRYSRGYGDRPAPGRVWSWLRENLSTRPRSVR"
     gene            2576..3370
                     /locus_tag="FCN18_RS30135"
                     /old_locus_tag="FCN18_30130"
     CDS             2576..3370
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015101122.1"
                     /locus_tag="FCN18_RS30135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_30130"
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="WP_110343885.1"
                     /transl_table=11
                     /translation="MSGSIVVRAVGVHKWYGDVHALRGVDLDVPRGSVVCLLGPSGSGK
                     STLLRCINRLEVPTSGGVEIEDDCIGYKREPGRLRPCSSRRLAAQRRCTGMVFQQFNLF
                     AHMTVLQNVMEGQTSGLGTPKAQARERAFELLDGVGLVDKADHYPGHISGGQQQRVAIA
                     RALASNPKVLLFDEPTSALDPELVGEVLAVMRSLAQEDVTMIVVTHEIEFAAEVATEVH
                     FMCDGSIVESGNPRQVIDAPQQERTQYFLAHMRKRRSADTKA"
     gene            3379..4590
                     /locus_tag="FCN18_RS30140"
                     /old_locus_tag="FCN18_30135"
     CDS             3379..4590
                     /EC_number="4.4.1.13"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_function="GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (39-388). E-value:
                     3.1e-36. Score: 117.2. Matches aSDomain:
                     nrpspksdomains_FCN18_RS30140_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012382.5"
                     /locus_tag="FCN18_RS30140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_30135"
                     /product="MalY/PatB family protein"
                     /protein_id="WP_137096682.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 5.6e-36, bitscore:
                     117.1, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKYHDRRGWKQLTISDLASWSVANSRARRCKRWSLYPAEIIDLT
                     VAEMDLPVAEPIMAAVRDAVDRQAFGYPLPGHDSELPAAAAEWLTAQGLAVQPEHVNLI
                     SDVIKGMVLGLRHFAPPHTPVVVITPTYSRFLDAVEAAQRQVIEVPMLLGENGYSLDVP
                     EIEKALRQGARTVLLCNPSNPVGRVFNHSELAELSVLVERFGARVISDEVHSPLRYGTK
                     FVPYASVSSAAAEHSITLTSASKAWNIPGLRCAIMVLTNPADQLTWDVLPRASKGGISP
                     LGIEASTAAFKQGQPWLNEAIKLLDVNRLAVGDYLKRAGLGGVMCMPEATYLAWFDLRE
                     FGHPDPQRYLMENAGVATTSGDEHGVGGAGFVRVNFATPQSVLLDALERMTSALRRSPT
                     RNSS"
     aSDomain        3496..4542
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FCN18_RS30140_Aminotran_1_2.1"
                     /evalue="3.10E-36"
                     /label="FCN18_RS30140_Aminotran_1_2.1"
                     /locus_tag="FCN18_RS30140"
                     /protein_end="388"
                     /protein_start="39"
                     /score="117.2"
                     /tool="antismash"
                     /translation="EIIDLTVAEMDLPVAEPIMAAVRDAVDRQAFGYPLPGHDSELPAA
                     AAEWLTAQGLAVQPEHVNLISDVIKGMVLGLRHFAPPHTPVVVITPTYSRFLDAVEAAQ
                     RQVIEVPMLLGENGYSLDVPEIEKALRQGARTVLLCNPSNPVGRVFNHSELAELSVLVE
                     RFGARVISDEVHSPLRYGTKFVPYASVSSAAAEHSITLTSASKAWNIPGLRCAIMVLTN
                     PADQLTWDVLPRASKGGISPLGIEASTAAFKQGQPWLNEAIKLLDVNRLAVGDYLKRAG
                     LGGVMCMPEATYLAWFDLREFGHPDPQRYLMENAGVATTSGDEHGVGGAGFVRVNFATP
                     QSVLLDALE"
     gene            4706..5923
                     /locus_tag="FCN18_RS30145"
                     /old_locus_tag="FCN18_30140"
     CDS             4706..5923
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1268: mandelate racemase/muconate lactonizing enzyme"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024771.5"
                     /locus_tag="FCN18_RS30145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_30140"
                     /product="enolase C-terminal domain-like protein"
                     /protein_id="WP_110343887.1"
                     /transl_table=11
                     /translation="MNRDEDSDGRKSVVVESNFAKSVIGDVRVHLVRLPGMTNVFREEA
                     AIVEVQTEDGVSGWAEANGLLLALKAHVEADRPHPRDRGPRAALVGQQFADVHAAVEAL
                     RSNTTLSGRSGLGRVANGAIETALFDLAGRLDGVPAWHLLLGSAEGPEQHVITPYITIF
                     NRGSYPDVVAKAKEDIDRARSFGYRHFKIEATSYNTDERQAVTIVDEVRSHVGDSVTLF
                     VDNVYRWAEYTAGAEAAKAYKSLGAEFLEDPFLPEQWEWWRRLRDEVGLPLATGGGMET
                     LERFLAQMEFANTDILQPGAHVAGLLGAHEVAQAAAKRVRSITPFGVSATTLATGGALH
                     LAAANPNVKYIEYAPANLFRVLRLRSDVTPDEPELRPDGTFLAPTTPGIGVDCDTDAID
                     KYRVSG"
     misc_feature    5561..5563
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            <7403..>8204
                     /locus_tag="FCN18_RS30155"
                     /old_locus_tag="FCN18_30150"
                     /pseudo=""
     CDS             7403..>8204
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011689697.1"
                     /locus_tag="FCN18_RS30155"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /old_locus_tag="FCN18_30150"
                     /product="IS256 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MAAELVAQARERGLELTGPDALLKMFTKNVLETALNEEMTEHLGH
                     EKNHAEFGRDSSNVRNGTRSKTVISDAVGEVEVEVPRGRESTFEPKIVKKRQRRLTDVD
                     EIVLSLYAKGLTRGRFLRISLKSMAPRCRRKPSHGSPTRWSPRCRSGPAVRSIPCTPRC
                     SLTRSWSRCVMGR"
     misc_feature    complement(8216..8233)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.78"
                     /tool="antismash"
     misc_feature    complement(8590..8604)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.92"
                     /tool="antismash"
     gene            8767..9123
                     /locus_tag="FCN18_RS30165"
                     /old_locus_tag="FCN18_30160"
     CDS             8767..9123
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FCN18_RS30165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FCN18_30160"
                     /product="hypothetical protein"
                     /protein_id="WP_110343890.1"
                     /transl_table=11
                     /translation="MSDEDLDVTTARLYRGLVEQPGAEFTANPLAAGLEVPVTEVERVL
                     GRLLEANLVTETGDERYRLYDLVRDHVTPLTDQDDEARAPRGTSSDDRVVPAAHRGGRQ
                     GHQPVPPSVQPRLL"
     gene            9470..9703
                     /locus_tag="FCN18_RS30170"
                     /old_locus_tag="FCN18_30165"
     CDS             9470..9703
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FCN18_RS30170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FCN18_30165"
                     /product="hypothetical protein"
                     /protein_id="WP_110343891.1"
                     /transl_table=11
                     /translation="MAEIRRIGHSPARTSRPTNSHAARPDLERALEIAEDPKIADAKLA
                     VHHLRLAASMFAGISDHIGHARTVMHLARASP"
     gene            complement(10001..10273)
                     /locus_tag="FCN18_RS30175"
                     /old_locus_tag="FCN18_30170"
     CDS             complement(10001..10273)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     triceptide: triceptide_precursor"
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012610.5"
                     /locus_tag="FCN18_RS30175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_30170"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_158303191.1"
                     /sec_met_domain="triceptide_precursor (E-value: 1.0,
                     bitscore: 10.0, seeds: 0, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIFLQVSWDNRADRIDHDGPDFVWEQVAADLRADIESGALAPGV
                     RLPSESALASIYGVARGTIGRALLKLKEDGLVVTRFGRGTFVART"
     misc_feature    complement(10046..10048)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            10447..10797
                     /locus_tag="FCN18_RS30180"
                     /old_locus_tag="FCN18_30175"
     CDS             10447..10797
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FCN18_RS30180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FCN18_30175"
                     /product="hypothetical protein"
                     /protein_id="WP_137096685.1"
                     /transl_table=11
                     /translation="MSPTDEQCLRIADALLDDNVAQAEVYLWAAWHPTAEFPDEDYSSE
                     ERAWATAIRTLRQPAAQDLESALVRLDQAICAETTHLLQHDDSAARDTLRSVGTHLLAR
                     GHTILTVTESQP"
     gene            10851..11411
                     /locus_tag="FCN18_RS30185"
                     /old_locus_tag="FCN18_30180"
     CDS             10851..11411
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FCN18_RS30185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FCN18_30180"
                     /product="hypothetical protein"
                     /protein_id="WP_110343894.1"
                     /transl_table=11
                     /translation="MIDVLCEITIASHGALEHLQHRGRGILEIARRRRRPLPRAHALGA
                     AETLFRREVHEAIGLLATYIEDSEIDEHYLNEVGAEVRIIAERMECFPREPLPPPPSND
                     ISVQLTRINHAVDAEAAMIYQLKDTGQPSATTYLRRRGLHLLELGMLETEQAGIDITAI
                     RSAISTAFNIPNQTNSESRGLCR"
     gene            complement(11616..11975)
                     /locus_tag="FCN18_RS40340"
     CDS             complement(11616..11975)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013775.5"
                     /locus_tag="FCN18_RS40340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphotransferase"
                     /protein_id="WP_245960223.1"
                     /transl_table=11
                     /translation="MRDTLGVDLHIRRWETIHNDLHWNNLLAPELGILDWEFWGRGPAG
                     TDAASLYCYSLLVPDVARRVWRTFGTVLDTDDGQRALLWVAARLLHRATKLGDHPALIT
                     PLHELTAPLLRSGGA"
     gene            complement(12447..13073)
                     /locus_tag="FCN18_RS30195"
                     /old_locus_tag="FCN18_30190"
     CDS             complement(12447..13073)
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_process="GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012235.5"
                     /locus_tag="FCN18_RS30195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_30190"
                     /product="AAA family ATPase"
                     /protein_id="WP_228714202.1"
                     /transl_table=11
                     /translation="MAELADNGLEFTAPVTMLVGENGSGKSTVVEAIAEAFKLDAYGGR
                     AGRKYGNDRPRTPLGEVVQLETTPEGARMRSGPRTKRKGFFLRAETAFGLMNAVSGMSG
                     HWEADTSEMSHGEGFLTVFAEMFQGGGLYLMDEPEAALSFTSCLQLVALMHDLGHSGAQ
                     VPTSSRSATTGHAGRSGTAWTSRRSGGGSSPSPRSTCGISLHDRG"
     gene            complement(13175..14104)
                     /locus_tag="FCN18_RS30200"
                     /old_locus_tag="FCN18_30195"
     CDS             complement(13175..14104)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     triceptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     triceptide: SPASM"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012783522.1"
                     /locus_tag="FCN18_RS30200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_30195"
                     /product="radical SAM/SPASM domain-containing protein"
                     /protein_id="WP_228714203.1"
                     /sec_met_domain="PF04055 (E-value: 8.3e-16, bitscore: 51.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 7.9e-09, bitscore: 28.7,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDADDAHAALTAVTCDRHLLTFLWLEITGRCQLECTHCYAGSSP
                     MGTHGTMTPDGWRGVLDQAAELGVTTVQLIGGEPTLHPALPELVHHALAHDVQVEVFTN
                     LVHISDELWHVFSRPGVSLATSYYSDDPDRHAAITGRPSLARTRANISKALRSGIPLRA
                     GLIDLADNQRVNEAAAELVNLGVPEIGRDRLRHVGRGGRGQPGTVGQLCGQCGRGSAAV
                     AADGIVWPCVFSRWLPIGNVRESSLAAALTSEKAAHVSNELRTAFADRPATMCVPTMCD
                     PQCGPSCSPACRPAGNCRPVGACAPDYG"
     gene            14726..15991
                     /locus_tag="FCN18_RS30205"
                     /old_locus_tag="FCN18_30200"
     CDS             14726..15991
                     /EC_number="2.7.7.65"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025: diguanylate cyclase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR00254.1"
                     /locus_tag="FCN18_RS30205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_30200"
                     /product="GGDEF domain-containing protein"
                     /protein_id="WP_110343895.1"
                     /transl_table=11
                     /translation="MTAHATGRHEQSAGDQRAASRLLPLRFTLYFVATVLAAGAIWAVA
                     ALTETIHGADGTTFGVLVVSGLVAGELAGQIERRRRRFSDTPHVNFSSVWTLAAALLLP
                     LDLVSLVAVVLYAHLWVRSWRGVTGVRAYRVVFSVANVIVSCQVAQWFARELGLFPLGS
                     ELALTGVLALAVVVLAYFATNSIIVGIAIALLHPGRSLAGLTGPASENVLELATLCFGT
                     VAAVLVSTEPWLVGLLVLPLYALHRSVLVTQLERAATRDGKTGLLNAASWRAQADAELD
                     RARRHDRAVGLLMIDIDRFRTINERYDRGIGDEVLGAVGATLRKGTRQEDLCGRLGGEE
                     FVIMLPGVAGQDLVRVADRLRRRIAETTIATGAPLPLQVSVSMGAASYPRAGSSVEELL
                     LAADNGLFAAKDGGRNRVVLAG"
     misc_feature    14789..14791
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    14864..14866
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(16007..16372)
                     /locus_tag="FCN18_RS30210"
                     /old_locus_tag="FCN18_30205"
     CDS             complement(16007..16372)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF013777.5"
                     /locus_tag="FCN18_RS30210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_30205"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_137096686.1"
                     /transl_table=11
                     /translation="MADWDMPYRQQVRDTLAVLNGDWTVAVLAALAPGERRFGELRAEV
                     NEVEERIGWASHTRPLSEKVLTTTLQRLHDEGLVERRAEGDRFGAVWYRLTPAGRSLLR
                     ALRSLVDWAREYRAPPP"
     gene            complement(17161..17460)
                     /locus_tag="FCN18_RS40345"
     CDS             complement(17161..17460)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FCN18_RS40345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_228714204.1"
                     /transl_table=11
                     /translation="MANTPSAAPQAKPKFVQRFSAAAAIVKHAKPPAVIAATIGNGKRP
                     DRTSVIVSTQLIAHAQHHATATGPGPNRAHPTANNTAHPTDAATSTTTHELHGP"
     gene            17459..17707
                     /locus_tag="FCN18_RS40350"
     CDS             17459..17707
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FCN18_RS40350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_228714205.1"
                     /transl_table=11
                     /translation="MAAAVQAVAPEHTGGGDTALYGAVALYLGWFGWNVLATGLLLAAG
                     LTAVVAIAVAVVTHQARARFPAGPSVLAGALLGMLFA"
     gene            17826..18347
                     /locus_tag="FCN18_RS30220"
                     /old_locus_tag="FCN18_30215"
     CDS             17826..18347
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FCN18_RS30220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FCN18_30215"
                     /product="hypothetical protein"
                     /protein_id="WP_137096687.1"
                     /transl_table=11
                     /translation="MAVALGASLLVSGCSGERPSAPPPLDSSAPSQGSLAPSASLDAAA
                     AVEAAYTQFWPRSAQTPHKPEDTWRDAIAAIAIEPQLSVTLEAMRRNKAAGFTTYGEVV
                     VRITSVEVSGDTAKVVDCQDASRAGQADARTGDPKTVGVPRMPVTATMKRDQASGQWKV
                     ARLRFPGGAC"
     misc_feature    18081..18083
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            18305..19285
                     /locus_tag="FCN18_RS40355"
     CDS             18305..19285
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FCN18_RS40355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_228714206.1"
                     /transl_table=11
                     /translation="MEGGSTALSWGCVLMHRGLLAIPACLAAATGVLAASPSAAADEPH
                     DDGQVVVTPVDPYGQYTPPRVDLRALYSRGEAPIRRGGPQATSSPGSLAGTDGTGTADA
                     SSGLPPGCFLGGFPVGDGPGGIRSGGNAVGLRCLPSVPADAPPGAQAPGPPPLPTPAEL
                     AARAFEQLRLPLPVPRHSPDVRLPDGRDATIVGENTWVWTDRSVWHPAVQRVQVGPVWA
                     EVTATPVAMLFNSGTGGSMSCAGPGTPYDRSYGLHAASPDCGFVYTRSSVGQPNDQATA
                     EWAIQWSVSWVGSDGTTEVGGDFPQMSSRAAATFAVAEVQALRAN"
     gene            19387..20085
                     /locus_tag="FCN18_RS30230"
                     /old_locus_tag="FCN18_30225"
     CDS             19387..20085
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009155747.1"
                     /locus_tag="FCN18_RS30230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_30225"
                     /product="SAF domain-containing protein"
                     /protein_id="WP_110343899.1"
                     /transl_table=11
                     /translation="MGTAVSFSRPPQPRSGDSGLTGQGEEGDGPRVPRRRRWWLLGVAV
                     VLAAVVAYGNHALIAGQDERVDVLVLTRDVGWGQRIGEGDLGVAKAVPDQRLASIPASD
                     RAGVVGQVARSTLPAGTVLAPGQLSAQPVPGPGERLVGLPVKPGHLPARGLAPGDLVQV
                     TPVAGGTGTDASQSTASTAGPFRARVLGVGPPDSTGAVTVDVLVGADTAQAASSAAAGQ
                     VVLVQLGPGA"
     gene            20126..20953
                     /locus_tag="FCN18_RS30235"
                     /old_locus_tag="FCN18_30230"
     CDS             20126..20953
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009155746.1"
                     /locus_tag="FCN18_RS30235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_30230"
                     /product="hypothetical protein"
                     /protein_id="WP_110343900.1"
                     /transl_table=11
                     /translation="MITIVSGKGAPGATTTLAALAAAWPVPVVLADCDPAGGDLAAGWL
                     GQWVVDGTIRTDLGVLSHATATRHATAGDPATLLDHVQQVPPARHVGLLAGLSAPGQHA
                     AVGTAGWTRLTAALAAFKTTSGHPADALVDIGRYSTLTPWPLLLAADLVLVAVRPTQRH
                     ILAARPLLAELAERIVPHRLGLAVCATTPAGSREVRAALGREAGVQVAADARAAAVFSD
                     GADGGTLPRRSPLLRSVRRAARRLHGTYHQDTPAELRTPAAPGSPGVLTGGAR"
     gene            20950..22467
                     /locus_tag="FCN18_RS30240"
                     /old_locus_tag="FCN18_30235"
     CDS             20950..22467
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020670176.1"
                     /locus_tag="FCN18_RS30240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_30235"
                     /product="CpaF family protein"
                     /protein_id="WP_110343901.1"
                     /transl_table=11
                     /translation="MTLPHNGYRPTTGPTAPRRPPDLSAPFAGALGTGPAAPPAPTAPP
                     DGATGGYLDPQAVRAIRESVAARLEQVAAGEAHLDSPLSVEEQQARMRAYVAEEVTAWV
                     QRRAAAGQAPLPVDDERRLVRAVVAALSGLGALEELLEREDVENIHVHGCDHVFLELAD
                     GSIERWPHPVADTDAELVEMLAAMFARQGQTSREFNAGRPMGNLRIPAGGPLGARVAAV
                     MEVSDRPRVAIRRHRLVNVGLDDLVANGTLDPLLASFLRAAVRAGCNTVVSGGPAAGKT
                     TMLRALCREIPAFEHVVTVEEEYELGLHIGPRPLVTPLEARPANSEGIGEITLDDLLKQ
                     TLRHSPSRVIVGEVRAGEVTAMLRALGNGATGGMCTLHAISASAVFDRIGALGQLADPP
                     LAIDAAHQWTASAIDLVVHVARTDHPGRRERFIAEVIEVGPVGDSGRPDTTRIFGPRPV
                     DGRAVPAYAPSRDLLERLERHGFDRAALDAAGSGTWHTAGFPDAGLR"
     gene            22464..23405
                     /locus_tag="FCN18_RS30245"
                     /old_locus_tag="FCN18_30240"
     CDS             22464..23405
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016334814.1"
                     /locus_tag="FCN18_RS30245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_30240"
                     /product="type II secretion system F family protein"
                     /protein_id="WP_110343902.1"
                     /transl_table=11
                     /translation="MTTVWPWLLGLAAVLAVACAVAAFLPLAARQPDESARATTPWGLL
                     AWRAVVARVPLRRVLLAVAAGAVVWWATGWPVAAIIAAAGVITVPILARGHDAQRLITR
                     LDALASWVRRLADVLASGAGGLEQAIASSARTAPEALATEVETLAVRLRTRGLEQALRA
                     FAEDVGDEAADEVVLALILRSRAGGRGLVDILDAKATALEREVVARRDIEADRAKPRTD
                     VRAILGITAVLLAGLVFFAHEFLTPFNDVLGQLVMAGIGGLLGAAGWWMHLLTRTRRPA
                     RLLGAASRTPVGAPKPTRKAAVVAPAGEGVPR"
     misc_feature    complement(23429..23443)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 22.41"
                     /tool="antismash"
     misc_feature    23430..23444
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 22.41"
                     /tool="antismash"
     misc_feature    complement(24090..24104)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
ORIGIN
        1 cggatattcg aagatctcgg caagtatatc cgcgtctgga ttccagcgat agacggcaat
       61 ccgtgaggta cttagcgcat cgatacttac cgaaggttgc tcggccaacg gatgtcgggg
      121 atggctcacg gtgagcagtc tggagcggca caagttgtgc gccgtgatgc ttgccggaaa
      181 agcctgattg atgaccagtc cgatatccgc tgttccatcc agtaaaaggt cgattacttc
      241 acgactgtgg gcgactcggc agtgcgcttg taacgacgaa tcgctcaaga tcttgagtac
      301 cggtgggaag agttccgttc ccaggctggc gggcgcggca agaatgagcc ggctggatgc
      361 ctcggttccc actgcctggt gagcctcgcc gagtaagtcg agacagcgac gtgcgtaagg
      421 caccagtcgt tctccggctg gggtgagcgt tgacccgcgg gctgtgcgtg cgaacaactg
      481 cgtcgtcagt ttgtgttcca gcgtggcgat gcgtgcgctc acggagggcg tcgcgagtcg
      541 cagttccctg gccgctgtgc cgaagcttcc ggcgcgggca acggtgagga atacaacgag
      601 atcgaatgtt tccaggctct catgagtagc cataggccca gcctaacact ggcgacaggg
      661 agatgccacc taccgcgcta gcgtacacgc tgccatgctg gcgaaacccg cgcgaagtct
      721 atataggagc acctaacggg cagatcggag actccgatgg caaagcgttc tcctcgattg
      781 aaaacactga tggcagcggc gctatcgctc gcgctggtca gtacgtcctg cgggaccaat
      841 tccggggccg ttggttcgaa caattctgcg ggcctgccga ccactttggt ggtcgctacg
      901 ggtgactaca aggttccgac gagcttcttg aacaagaagg gcgagctgga cgggttgaac
      961 gtggacctca ccagggcgtt gggccgtcgg ctcggcgtcg agatgaagct ggtggccgtt
     1021 ccgttcgacg ctgtgattcc cggtatacaa tccggccggt ttgacaccgc tctcttcaat
     1081 gtgagcgata cgccggagcg gcgcgcggtc gtcgaccttg tcgactacgc gccatcgggc
     1141 actgtgattg tgacacgaaa aaatgatcgt aaggggatca cggccaaccc acttacccta
     1201 tgtggccgga cagtcgcggt gaaggcgggg cagaccgagt ttaatatcct gaacaaggac
     1261 gtgtcgccga aatgcaaaga gacgggcgaa cctgcgatca atttccagac tttcaaggac
     1321 gacaacggct tggaattcgc cgtggagact gggcgtgccg acgccttcct cgggggcacc
     1381 acggtgacgc cctacttcgt cagcaggaac tctgacacgt tcgagatcgt gggcaaactg
     1441 ccgattgcgc tggatccgct gggtatgccc ttcgcgaagg ggcgcgatga cctggtgggt
     1501 gccgtgctcg ctgcatggaa ggagatatgg cagagcggtg agtacgagcg gatcgcgaag
     1561 aagtggtcac tgcaatcaat tgttccaaag gatatctcgt tgttcaccgt gaacgggggc
     1621 gacaagtcat gacatcgctt accgaaagcc gggagacgtc gctcgaccgc gatcgggcta
     1681 ccgccgagga cttcgaggtc aaaccgggcc tgcatatcgt gcggtgggtc gtggcgggcg
     1741 tggttctcct ctttgctgcg caactggtat acggcgcggc gaccaatcct cggctgtcct
     1801 gggacatcgt ggccgactac ttctttgacc cgcagatact tgatggcctg ctcgtcacct
     1861 tgggattgac gatggtctca caggtgcttg caactgtcat cgggctcacc gtggcgctca
     1921 tggcgctgtc acacaatccg gtgctcgtgg cggtcgctcg catctacgtc gctgtgtttc
     1981 ggacagttcc cacgatggtg cagatgttgt tctggtacta ccttgcggcc gtcgtaccag
     2041 tcttgtcgat tggcatccca tttggtccgg accttgtcac actcgacaca aactcggtaa
     2101 tgactcagtt cgcagcggca ttgctcggtc tcgcacttgg cgaggcagcg ttcttggcgg
     2161 agtacttccg tggtggaatc atctcggtac cgcgtgggca gatcgacgca gctgcggctt
     2221 gtggactgac accggcgtgc acattccgcc gcatcgtgct tccgcaggcg ctcagggtga
     2281 tcctgcctgc ctatggcaat gccatgatta ttaacatcaa gaacacctcg ctagtcttcg
     2341 taatcggggc cggcgacttg atgacgcgcg cccagctcat ctactcccag aacttccagc
     2401 agattccgct cttgattgtt gtcagcggct ggtacatggt gatcgtcttg ctgctcacct
     2461 ggctgcaacg tcgtatcgag gttcgatatt cacggggtta tggagaccga ccggcgcccg
     2521 gaagagtgtg gtcctggctc cgtgagaacc tgagtacgcg gccgaggagc gtgcgatgag
     2581 tggaagtatt gtggttcggg ccgttggtgt tcataaatgg tacggcgatg tgcacgcgct
     2641 acgcggcgtc gatctcgatg tcccccgagg aagcgtggtc tgcctcctcg ggccctcagg
     2701 ctcaggtaag agcacccttt tgcgttgtat caatcgactt gaagtaccga cttccggcgg
     2761 tgtagaaatc gaagacgatt gtatcggcta caagcgggag ccgggacgtc tccgtccgtg
     2821 cagttcacgg cgtcttgcgg cgcaacgtcg ctgcaccggg atggtcttcc agcagttcaa
     2881 cctgtttgcg catatgacgg ttctgcagaa cgtgatggag ggccagacaa gcggtctggg
     2941 tacgccgaag gcgcaagccc gtgagcgcgc gttcgaactg ctggacggcg ttggtcttgt
     3001 ggacaaggcc gaccattacc cagggcatat ctccggaggt cagcaacaga gagttgcgat
     3061 cgcgcgtgcc ctcgcatcga atcccaaggt gctgctgttc gacgagccga cctcggcgct
     3121 tgatcctgaa ctcgtgggcg aggtcctcgc agtgatgcga tcgctcgcgc aggaggacgt
     3181 gacgatgatc gtggtgaccc acgagatcga atttgcggca gaggtcgcga cggaagtgca
     3241 tttcatgtgc gatggctcaa ttgttgagag cggaaacccg cgccaggtga tcgacgcgcc
     3301 acagcaggag cgcacacagt acttcctcgc tcatatgagg aaacgtcgca gtgcggacac
     3361 aaaagcatag aacttatcgt gagtaaatac cacgacagaa ggggctggaa gcagttgacc
     3421 atttcagatc tggcgagttg gagtgttgcg aattccagag cgcgacgttg caaacggtgg
     3481 tcgctatatc cggcagaaat catcgacctg accgttgccg agatggacct gccggtggcg
     3541 gaaccgatca tggctgccgt acgcgacgcg gttgatcgcc aggccttcgg gtatccgctt
     3601 cccgggcacg acagcgagtt gccggccgcc gcagcggaat ggctaaccgc acaaggtctg
     3661 gcggtacaac ccgaacacgt caacctcatt tcggatgtca tcaaagggat ggtgcttggc
     3721 ctcagacatt tcgctcctcc gcatactcct gtcgtggtta tcacgcctac gtacagtcgt
     3781 tttctggacg cggtcgaggc cgcgcaacga caggtgatag aggtgccgat gctactcggt
     3841 gagaacggct acagcctgga tgttccggag atcgaaaagg ctcttcggca gggcgcgcgg
     3901 accgtgctgc tgtgcaatcc gagtaatcct gtgggccggg tcttcaacca tagcgagcta
     3961 gctgagctca gcgtgctcgt agagcggttc ggcgcacgcg tcatcagcga cgaggtccat
     4021 tcgccgcttc ggtacgggac gaagttcgtg ccttacgcga gcgtaagttc ggcggcggcg
     4081 gagcattcga taacactgac aagtgctagc aaggcgtgga acatcccagg actacgctgt
     4141 gcgatcatgg tgctaacgaa tccggcggat cagctcacct gggacgtact gccgcgcgcg
     4201 tcaaaggggg gcatctcgcc tctcgggatc gaggcctcta ccgctgcctt caaacaaggg
     4261 cagccatggt tgaacgaagc gatcaaactg cttgacgtca accggctggc agtcggcgac
     4321 tatctgaaaa gggccgggtt ggggggggtc atgtgtatgc cggaggcgac ctacctcgcc
     4381 tggtttgacc tacgcgagtt cggccatccg gacccccagc gctacctgat ggagaacgcc
     4441 ggtgtggcta ccactagcgg tgacgagcac ggcgtcggcg gcgctggatt cgtcagggtg
     4501 aacttcgcga ctccccagag cgttctgctg gacgccttgg aacggatgac aagtgcgcta
     4561 cgtaggtcgc cgacccggaa ctcgtcctga ttgcccgcag attgacgatt gacctcatcc
     4621 tgggccgagt gttgtcggcc gtagcaacgt cgcgtacctg tcggccgggc tttggtgagt
     4681 ggctggcccc tgcgccggag cggtgatgaa cagagatgaa gactccgatg gaaggaaaag
     4741 tgtcgttgtg gaatcaaatt ttgccaaatc ggtaatcggc gatgtgcggg tgcatctcgt
     4801 gcgattgccg ggtatgacga acgtcttccg agaggaagca gcgattgtcg aagtgcagac
     4861 agaagacggc gtcagcggtt gggcagaggc gaatggcctg ctgcttgcgc tcaaggcgca
     4921 cgtagaggcg gaccgtccgc atccacgcga tcgcggcccg cgggccgcgc tggtgggcca
     4981 gcagttcgct gatgtccatg ctgcggtgga ggcgctccgc agcaacacaa cgttgtctgg
     5041 acgttccggg ctcggtcgtg tagccaatgg tgcgattgag acggcgctgt tcgatctcgc
     5101 cggtcgactc gacggcgtgc ccgcctggca cctacttcta gggtcggccg aaggtcccga
     5161 gcagcacgtc attactccct acatcacgat cttcaatcgt ggcagctacc ccgatgtggt
     5221 tgccaaggcg aaggaagata tcgaccgtgc caggagcttc gggtaccgac atttcaagat
     5281 cgaagcaacc agttacaaca ccgacgaacg tcaggcggtg acgattgtcg atgaggtgcg
     5341 ctctcacgtc ggtgactccg tgacgttgtt cgtcgataat gtttaccggt gggccgagta
     5401 taccgccggc gcggaggccg cgaaggcgta caagtcattg ggcgccgagt ttctcgagga
     5461 cccttttctg ccggagcagt gggaatggtg gcggcgcctt cgagacgagg tcggtctgcc
     5521 gctcgcgacg ggcggcggta tggaaacgct ggaacgtttc ttagcgcaga tggagttcgc
     5581 gaacacggac atcttgcaac caggcgcgca tgtggccggc ttgctggggg cgcacgaggt
     5641 agcgcaggcg gctgcgaagc gggtcaggag tatcacgccg tttggcgtat cggcaacgac
     5701 actcgcaaca ggcggtgcgc tccacttggc cgccgcaaat ccgaacgtga aatacattga
     5761 gtacgctcca gcgaatctgt ttagggtatt gcgtctgagg tcggacgtaa cacccgacga
     5821 gccggaattg cggcccgacg gcacgttcct ggcgcccaca accccgggta tcggagtcga
     5881 ctgcgacacg gacgccatcg acaagtaccg ggtgtcgggg tagccagctg gcggacgcta
     5941 gctgggtgac tagccgcagg gtcgccgggt gtgtcggcac ctggcggcct ttgcgtgcgt
     6001 acgccgggct acctgaccgg atctgcgccg gacatggtgc ccgcgcgaat ctcaggagag
     6061 gtcgggcgtc cgtcgtagtc gcagcaatgg ccctcagcct cgaccctgtg tgtcaacaag
     6121 gggcggaaag gggaggacgg ccgtcccatt cctacatccc ggcgaccacg ttggcggtga
     6181 tcccggaggc tggttcgtag cgccggttgg agatggtccg ccgttgacgt gtgcggccag
     6241 ccaccagggt cagtgaaccc ttgaacgcgc agtccgccca gcgtggcgcg gcacaatagg
     6301 ctcgagttcg tggcaacggc tgtcggacag ctccgggaga gaccgaacgg ctacccgcat
     6361 gtctggggtc tagggcggta tccctcccag atgacgagtt gaccgagggg ctcacgctgc
     6421 gggcagaccg caatccgcct gcggcccggc gtcgtcgccg agctgcacta cgacaacagt
     6481 ctggtacgtg cttgggcgtt ggatgagcga accggctccc caaccgggcg ccttcaccgc
     6541 cgatctggac gcggcgacga gatcgccctc ggcgctgtcg ccacgtcgct cgttgcggct
     6601 gaactgctcc acggcaggcc gttgcgctcg gtcgactcga acgtcaccgt ggtggacttg
     6661 tgcgcggccc catccttcgc ccgtgtcgcg gctgtgagtg cggcgcgggc tccggctgcc
     6721 gactgcgacc gtcgagatga accggcccct gtctagctcg ccgttgacgc ccatcctcgt
     6781 agcgttgatc tgatacacct catcggccag tacccggaag gagcgggatg gtggggaaac
     6841 cgtgcgagtg agtggcgcgg gtagccttgg atctacgacc tgtgtaccaa tcaacatttc
     6901 acactcaagc agaacccact gcgccgtcaa cacctggacg atttcgtcga gcgctacgcg
     6961 tccgaaacgc cacgctccga gcggatcgag tccgaacgat tcaggccgtt catctatgac
     7021 gcccttctcg cgcgcgacaa ggtcaacctc gacatcacgt ggctccgtga tgagtcactc
     7081 gaagacaccg acaaccttcc agccccacac ctcatcgccc gcgagatcat cgaggacctc
     7141 accgccgcac tggtcgaact cgaagtcgtc gctgcggcgc tcgaactgtc atccggcgga
     7201 atgtccgact gaagaatgac tcggacatcg agagtcctcc ggtcaatgct tgtcaggggg
     7261 actgtttcac ggacggtgtt tccgaccgac acgccgggcg tgagttcggc gggacggaca
     7321 ctgtgagtga tgacatctga tgctgtgagc gcatcgagga agaccaacaa gcaggagcaa
     7381 cagctgtcgg cggagcaggc gggccgcggc cgagctggtg gcgcaggcgc gcgagcgtgg
     7441 gctggagctg accgggccgg acgcgctgtt gaagatgttc accaagaatg tgctggaaac
     7501 ggcgctgaac gaggaaatga ctgagcatct cggtcacgag aagaaccatg ccgagtttgg
     7561 acgggactcg tcgaatgtgc gtaatggtac gcggtcgaag acggtgatct cggacgccgt
     7621 gggcgaggtg gaggtcgagg ttccgcgtgg tcgggaatcg acgttcgagc cgaagattgt
     7681 gaagaagcgt cagcgtcgat tgaccgatgt cgatgagatc gtgttgtcgc tgtatgcgaa
     7741 aggtctcacc agggggagat ttctgcgcat ttcgctgaaa tctatggcgc ctcggtgtcg
     7801 aaggaaaccg tctcacggat caccgacaag gtggtcgccg agatgcagga gcgggccagc
     7861 cgtccgctcg attccgtgta cgccgcggtg ttcattgacg cgatcgtggt caaggtgcgt
     7921 gatgggcagg tgaccgaccg gccgttctac gccgctgtcg gcgtcaccac ggacggctgc
     7981 aaggaggtcc tgggcctgtg ggccggcagc ggcggcgagg gcgccaaatt ctggatgagt
     8041 gttctcgtgg acctgaaaac cggggtgtta aagacgtttt ctttctcgtc tgcgacgggc
     8101 tgaaaggact gcccgaggtc gtggagaacg tctggccgag cacgatcgtc cagaactgca
     8161 tcatccactt gattcgcaac tcattccggc tcacctcgaa gaagtacgtg aaagattcac
     8221 atgccgttga caactcggcc gagtgaatcg tgccgctgct gaagtcgtgc tcaggtgcag
     8281 tgccgcctca tggatgcctc gcgagcgccg tgttgtccgc tctggttcag atcttgatgt
     8341 cgccggtcta atcgcccgca ccaacccggc cgacttcggg caacggagac gtcccaccgg
     8401 cccgcgtcga ccaggtgtac agcaggtcag gctcatgatg acgagccggg cgggggaacg
     8461 tcacggtgat ggcgacgcaa aagggtgcgt gcggcctcaa cacgctagtt gatcgtgacg
     8521 cgccatcgct gttccgcatc tacgactacc tactcagcgg cgggcacaat ttggccgccg
     8581 accggctcgt ggccgacaag atcgcagctc tggtgcccga atgtggcgtg ccatcgctgg
     8641 gcccacctcg ccgcgcatcc tcggcgcgac ctcgcgcttc tgatcaccgg cctgcgccac
     8701 catcccgcca aggcttcatc cggcgccttg gattcgcacg agctgcctgt cggaggagtg
     8761 ctgcagatga gcgacgagga cctcgacgtc accaccgccc ggctgtaccg cggcctggtt
     8821 gagcagcccg gcgccgagtt caccgccaac ccgctggccg ccggcctgga agtcccggtg
     8881 accgaggtcg agcgagtact cggacggttg ctggaggcca acctcgtcac cgagaccggt
     8941 gacgagcgct accggctgta cgacctggtg cgcgaccacg tgacgcccct gaccgaccag
     9001 gacgacgagg cccgcgcgcc tcgcggtacg tcgtcggatg atcgagtggt acctgcggcg
     9061 caccgcggcg gccgacaagg tcatcaaccc gttcccccgt cggttcagcc ccgtctactt
     9121 tagcctcgac acccgggatg ttccccgacg ccaaggccgc cctggactgg gtcgagaccg
     9181 aacgaggcaa cctcctggcc gcacaacagg ttgccgccga cagcggctgg gacgagctgg
     9241 tgtaccagtt cgccgacgcc ctgtggagcc ccctgcgccc caactacacc gcaagcgaac
     9301 tggtgtggtc ccagttcctc ggagccaacg cagccgccga cgccggacac atcctggaga
     9361 tcgtctgccg tacccggcag ggcttcggtg aaaccaacct cgaactccac gaggccgcga
     9421 tcgccatctg cgccatcgcc gtacagcgtg ccaccgaggt gtgcgatccg tggctgaaat
     9481 ccggcgcatt ggccactctc ccgcgcgcac ctcaaggccg acgaattccc acgccgcccg
     9541 cccggacctg gaacgggcgc tggagatcgc cgaggacccc aagatcgccg acgccaagct
     9601 cgcggtacac cacctacggc tcgcggcgag catgttcgct ggcatcagcg accacatcgg
     9661 ccacgcccgc accgtcatgc acctggcgcg agcctcaccc tgaacgggca ggccgccgag
     9721 gcgctgaccg aactgaccgc gatcgagcaa gccgtgcacg actacggctt ggttggctac
     9781 ctcgccgacc tatacaccgt gctgggcgaa gtccacgccg cgctaggcaa caccgccgag
     9841 gcccgccacc acttcggcag gtcatcgact gctacaccgt agccggccca ctccggctac
     9901 ggcgacaagc ggactcttga gcctgttctg aagctgatac ggaatgccgc agcggtaacg
     9961 gcgacggatt gatgtgcgag gtcaggcaac gcctggctcg ctatgtccgg gcgacgaacg
    10021 ttccccggcc gaagcgcgtg acgactaagc cgtcctcctt cagcttcaac agcgcacggc
    10081 cgatcgtccc gcgggctacg ccgtaaatcg aggccagggc cgactcgctc ggcaaccgca
    10141 cacctggcgc caacgcgccg ctctcgatgt ctgcgcgcag gtcagcagcc acctgttccc
    10201 agacgaagtc cggcccgtcg tgatcaatgc ggtctgcgcg attgtcccag ctcacctgca
    10261 ggaaaatacg cactcctatg cgcctacctt gccatagcga cgtccataga cggacacgga
    10321 ctcctacaga cgtccatagg agcctatatt ttacctgcaa taacgtgagg aggtagagtc
    10381 atgagagaac cacaagcgac gccgccaccc gcgcgtaccc accgcgcggc tcgggagggg
    10441 ttcaccgtgt cgcccaccga tgaacagtgc ctccggatcg ccgacgcact gctggatgac
    10501 aacgtggcac aagctgaggt atacctctgg gctgcgtggc accccaccgc cgagtttccc
    10561 gacgaggatt actcttccga agaaagggcc tgggccaccg ccatccgtac ccttcgccag
    10621 cctgctgcgc aggacctgga gagcgcgctg gtacggctgg accaggcgat ctgcgccgaa
    10681 acgacacacc ttctgcagca cgacgacagc gccgcgcgcg acacactgcg ttccgtcggc
    10741 acccaccttc tcgcgcgggg ccacacgatc ctcaccgtca cggagtccca gccatgatcg
    10801 tgcgacgact ccgccgatac gccagcctca cccgacggca atgggaggac atgatcgacg
    10861 ttctctgcga gatcaccatt gccagtcacg gcgcgctcga acacctgcaa caccgggggc
    10921 gcggcatcct cgaaatcgcc cgccgacggc ggcgccccct accacgagcg catgccctcg
    10981 gcgccgccga aacactcttc cgccgcgaag tacacgaagc gatcggcctg ctggccacct
    11041 acatcgagga cagtgagatt gacgaacact acctcaacga agtcggcgcc gaagttcgca
    11101 tcatcgccga acgcatggaa tgctttcccc gcgaaccact cccgccgcca ccatccaacg
    11161 acatcagcgt ccaactcacg cgcatcaacc acgccgtcga cgccgaagca gccatgatct
    11221 accaactcaa agacaccggc caaccctccg ccacgaccta cctccggcgc aggggcctcc
    11281 acctcctcga gctcggcatg ctcgaaaccg aacaagccgg catcgacatc accgccatcc
    11341 gctcagccat ctccaccgcc ttcaacatcc ccaaccaaac aaatagcgaa agtcgcggcc
    11401 tgtgcagatg acctggattt cgcaggaagt cacgggctgc ttcttcggct agcaaagcgc
    11461 gaacttgcct tccgcgcccc catcggacgc gcatcacaag tctgcgtcgt cgagtcggat
    11521 atcagctgcc caggcccggc ggatcgataa cgcacgagcg cgggattgcg aacacagttc
    11581 ggtccaaggg cacggtgatc gtctcgattg gcaactcagg cacctcctga cctcagcagt
    11641 ggcgcggtca gctcgtgcag cggtgtgatc agcgccgggt ggtcgccgag ttttgtggcc
    11701 cggtgcagca gccgtgccgc cacccacaac agggcccgct ggccgtcgtc ggtgtccagc
    11761 accgtgccga aggtccgcca gacgcggcgc gccacgtcgg ggacgagcag gctgtagcag
    11821 tacagcgagg ccgcgtcggt gcccgctggg ccgcgccccc agaattccca atcgaggatg
    11881 ccgagttcgg gtgccagcag gttgttccag tggagatcgt tgtggatggt ctcccagcgg
    11941 cgaatgtgca ggtcaacgcc gagcgtgtca cgcactcgcc gtgtgtcgat gccgcgcgtg
    12001 gcgtagcgag atgtcgacac ttggcgcaaa cggtccaggc tgtgcgcagg gactcccacc
    12061 aatcatccga cagatccagc ggagcctgga gaacatctgt gggcgagcac ggatgcccgc
    12121 ctaggacggt catgacgtcg gcgcggacgc gtcggtgctg gtcagccgcc tcccactggg
    12181 tggtgtcgag cacgcgcggt ttcggtaccc cacggatgat gttggcgtcg aggttgccag
    12241 tccagaagtc gctgccgtga tccagccatc gggtttgctc agagcccacc cgcaaccagc
    12301 agaggccgcc ggcgccacgg gcgacggcga cgacggaccg cagccgccag ccgaaggtcg
    12361 gtagctcgac gagggtcagc ccgaagtggg cggcggcgtg gtcgaggttg tcgcgcatcc
    12421 acgcgcgaaa cgcctcgtcg gaacgctcaa cctcggtcat ggagtgatat gccgcaggta
    12481 gaacgcgggc tcggcgagga accgccgcca ctgcgccgtg aggtccaggc cgtcccactt
    12541 cgcccggcgt gtcccgtggt cgccgatctc gatgatgtcg gcacctgcgc gccggagtgt
    12601 ccgaggtcgt gcatgagcgc cacgagctgg agacacgagg tgaacgacag cgccgcctcg
    12661 ggctcgtcca tgagatagag cccgccacct tggaacattt cggcgaacac ggtcaaaaag
    12721 ccctcgccgt gactcatctc gctcgtgtca gcctcccagt gcccgctcat cccggacacg
    12781 gcattcatca gcccgaacgc ggtctcggcg cgcaggaaga accccttccg tttggtgcgc
    12841 gggcctgacc gcatccgggc accttcgggt gtggtttcga gttgcacgac ctcgccgagg
    12901 ggtgtgcgag ggcggtcgtt gccgtacttg cggccggcgc gcccgccgta ggcgtcgagt
    12961 ttgaacgcct cggcaatggc ttccacgaca gtggatttcc cggagccgtt ctcgccgacc
    13021 agcattgtca ccggagcggt gaattcgagc ccattgtcgg ccagttcagc cacgcacggc
    13081 accgtgtagg gccacgaggt cagggcagcg ggtcgcagcc cctcggggat gaacgcgcgt
    13141 cggacagcat ccgcctctcc ctaatccctg ttcgtcagcc atagtccggt gcgcaagccc
    13201 caaccggtcg gcagttgcct gctggtcggc acgccgggct gcacgagggt ccgcattgag
    13261 ggtcgcacat ggtcggcacg cacatcgtcg ccggccgatc ggcgaacgcg gtgcggagct
    13321 cgttgctgac gtgggcggct ttttcgctgg tcaacgcggc ggcgaggctg ctctcgcgca
    13381 cattgccgat cggaagccag cgtgagaaca cgcacggcca cacgatgccg tccgccgcga
    13441 cagcggccga gccgcgaccg cattgtccgc agagctgacc gaccgtgccc ggctgcccgc
    13501 ggccgccgcg cccgacgtgc cggagccgat cgcggccgat ctcaggtacg ccgaggttca
    13561 ccagctccgc tgccgcttcg ttcactcgct gattgtcggc gaggtcgatc agcccggcgc
    13621 gcagcggaat tccgctgcgc agcgccttgc tgatgttggc acgtgtgcgg gcgagcgagg
    13681 ggcggccagt gatggcagcg tgccggtcag ggtcgtcgga gtagtaggag gtcgcgaggc
    13741 tgacgccagg gcgggagaac acatgccaca gctcgtcgct gatatgcacg aggttggtga
    13801 acacctccac ttgcacatca tgggcgagcg catggtgcac caactctggc aacgccgggt
    13861 gcaatgtggg ctcgccgccg atcaactgca cggtcgtgac gcccagctcc gcagcttggt
    13921 cgagcacacc acgccagcca tcgggcgtca tcgtgccgtg ggtgcccatc ggcgagctgc
    13981 ctgcgtaaca gtgagtgcac tcaagctgac agcggcccgt gatctccagc cacaggaacg
    14041 tcaacaggtg acggtcgcag gtgacagcgg tcagcgcggc atgggcgtca tcggcgtcaa
    14101 gcacgttcca gctagcggca tgccgcggag agggttgcga accgcggacg accagtcgcc
    14161 aaagaggtgc cacctcgccg cgacccctgc caacgccgct gtggctgatt ctgctccgca
    14221 gtcgtgtgta gagagatcga gcgacgcggc gagcgcgcac gtcggagagg cggtaacaga
    14281 ttcgaggtcg cgtgcggtct ccaagccacc catgacggag acggccttca ggtcatctgt
    14341 cattccgctg atgaccacgc aaagtgatac ggctacgaca atgtggtgaa ctcgcgggac
    14401 aatgtggcct cgtggcgtgt gctccggctt atcgtggacg atctggatgc gacggtcaaa
    14461 gcggtacgcg cgggctacgc caatggggag gtgagtaggc ccggtcgtga cgacgtcgtc
    14521 gtcactcggg cggcccagcc aggctcgtcg atgcgagcgg ctcgtcccca gggtcagtgg
    14581 ccgaggacga gccaggcgag ctgggtgagt cgatgccttc acaggtcctt gttgcgcatg
    14641 gcgagcctcc tcccacagat ggcggacggc cgagtctggt agcccgagcc gtcgcgagcg
    14701 ggcgcggaac gaaagcggga ccagtatgac ggcacatgca acgggtcggc acgagcagtc
    14761 ggctggcgat cagcgcgcgg catcgcgttt actaccgctg cgattcacgc tgtactttgt
    14821 cgcaaccgtg ttggcagctg gcgcgatctg ggcggtggca gcgttaactg aaacaatcca
    14881 cggtgcagat ggcactacgt tcggcgtgct cgtggtgtcc ggcctggtgg cgggcgagct
    14941 cgctgggcag atcgagcgtc ggcgtcggcg cttctccgac acgccacacg tgaatttcag
    15001 ctcggtatgg acgctggctg ccgcgttgct gctgcccctg gacttggtct cgctggtcgc
    15061 cgtggtgctg tatgcgcatc tctgggtacg aagctggcgt ggcgtgacgg gcgtgcgtgc
    15121 ctaccgcgtc gtgttcagcg tggccaacgt gatcgtgtcc tgccaggtgg cccagtggtt
    15181 cgcacgagag ttgggcctgt tcccgctcgg gtcggagctg gcactgaccg gagtgctggc
    15241 tctggcggtg gtggtcctgg cgtatttcgc gaccaactcg atcatcgtcg ggatcgcgat
    15301 cgcgctgctg catcctgggc gttcgctggc tggtttgacc gggcctgcga gtgagaacgt
    15361 gctcgagctg gctaccttgt gcttcgggac ggtggcggcg gtgctggtga gcaccgagcc
    15421 gtggctggtg gggttgctgg tgctgccgct gtacgcgttg caccgcagcg tgctggtcac
    15481 ccagttggag cgcgcggcga cgcgggacgg caagaccggt ctgctgaacg cggcgagttg
    15541 gcgcgcccaa gcggatgccg aactcgatcg cgccagacgc cacgacaggg ccgtgggcct
    15601 gctcatgatc gatatcgacc gcttccgcac gatcaacgag cgctacgacc ggggtatcgg
    15661 cgacgaggtg ctgggcgcgg tgggcgcgac gttgcgcaag ggcacccggc aggaggatct
    15721 gtgcggccgg ctgggtggcg aggagttcgt gatcatgttg cccggggtgg ccgggcagga
    15781 cctggtgcgc gtcgccgacc gcctccggcg ccgcattgcg gagaccacga ttgccactgg
    15841 cgcgcccctg ccgctgcagg tgagcgtgtc catgggggcg gcgagctatc cgcgggccgg
    15901 ctcgtcggtg gaggagttgc tgctggcggc ggacaacggg ctgttcgcgg ccaaggacgg
    15961 gggacgcaac cgggttgtgc tggccggctg accccggagt acgtggttag ggtggcggtg
    16021 ctcggtattc gcgtgcccag tcgaccaggg atcgcagggc gcggagcagg ctgcgtccag
    16081 ccggggtgag ccggtaccag acggcgccga atcggtctcc ttccgctcga cgctcgacga
    16141 gtccctcatc gtgcagtcgt tgcagggtgg tcgtcaggac cttttcgctg aggggacgcg
    16201 tgtgggaggc ccagccgatg cgttcctcga cctcgttcac ctcggcccga agctcgccga
    16261 accgtcgttc tcccggcgcc agggcagcca gtacggcgac ggtccagtcg ccgttgagca
    16321 cggcgagggt gtcgcgcacc tgctggcggt atggcatgtc ccaatcggcc accccggttg
    16381 cgtatcacga tcaacaccgc gggttgacga cccccggcga cccgatcggg tggtgtaccg
    16441 caagaccgtt ttcgagggct gacctggtgt aggtcgaacg ggtgaagatt gcccgactaa
    16501 ccctggggta agtcggtact taccttgcac tcagtcgagg tccgcgcgct acacgtagat
    16561 caatccgccg ccgcggatgg cgacagaggc gcgcagaggg gggacttggc catggttcat
    16621 cgtcgaccgt tgatgaccgc acccgatccc gctgccgggg tagcgagatg catcttctat
    16681 gggtgtggcg atgccggacg agatgctggc gtctggggag gcgcagcggg ctgtgctcaa
    16741 gctctgatag gcgcgttgct gagcatgcct ggccgctcag tgattcaggt ctttgcgttt
    16801 gcctggccgc tacgccgtgg ccaggtggct cccggcaggg atgacggcga tgagtgcacc
    16861 cgcgacgagg acagggctca atgcgagagt gctgcgctgg cgtggctgcc gagcggctcg
    16921 ccaggtcagg gtgatgtcgg ctgtggagag tcatgtcagg gccgaggccc cgtggtcgcg
    16981 ggtggcgacg ggggcaccgg tgagtcgggt gccggtgcgc cggtctggtg gtcgcggcgt
    17041 tggtcaccgg cgtgccgcgc ggggggtgtg tgggatgtcg acgatgttgt ggcttattgg
    17101 ggtcggagtg ctgcttggtc ccgggctggt cgccgttgcc gaacgcagcc tgggctctcg
    17161 tcagggacca tgcagttcat gtgtggtggt gctggttgcg gcgtcggtgg ggtgtgcggt
    17221 gttgttcgcc gtggggtggg cgcggtttgg accgggcccg gtggcagtgg cgtggtgctg
    17281 ggcgtgtgcg atgagctgcg tgctgacgat caccgacgta cggtctgggc gtttgccgtt
    17341 tccgatcgtg gccgcgatga cagccggagg cttggcgtgc ttgacgatgg ctgcggccgc
    17401 cgagaatcgc tggacgaact tgggcttcgc ctgcggggcg gcgctagggg tgttggccat
    17461 ggcggcagcg gtgcaggcgg tggcaccgga gcacaccggc ggcggggaca ccgctctgta
    17521 cggggcggtc gcgctgtatc tgggctggtt cggctggaat gtcctggcga ccggactgct
    17581 gctggctgcc ggcctaaccg cggtagtcgc catcgcggtc gcggtggtca cgcaccaagc
    17641 gcgcgcccgt tttcccgccg gtccttccgt gctggctggc gccctgctgg ggatgttgtt
    17701 cgcgtagcga accgatcgac gctgagcgtc ggctcgcgcg gagcggacgg ctctgcgagt
    17761 tcgacagcgt gggggaatgc gtgatggctt gctcgatctg gcgctcgtcg gcctggggtg
    17821 tcatcgtggc ggtggcgctc ggcgcttcgt tgctggtgtc cgggtgcagc ggcgagaggc
    17881 cgtccgcgcc accgccactg gattcgtctg cgccatccca gggatcgctg gctccgtcgg
    17941 cgtcgctgga tgcggcggcc gcggtagagg ccgcgtacac ccagttctgg ccgcgttcgg
    18001 ctcagacgcc gcacaagccc gaggacacct ggcgtgacgc gatcgccgcg atcgccattg
    18061 agccgcagct gagcgtcacg ttagaggcaa tgcgccgcaa caaggcggcc gggttcacca
    18121 cctacggtga ggttgtcgtg cgtatcactt cggtcgaggt gagcggcgac acggccaagg
    18181 tggtcgactg tcaggacgcc tcccgtgcgg gccaggccga cgcgcgcacc ggtgacccga
    18241 agaccgttgg cgtgcctcga atgccggtca cggcgacgat gaagcgcgat caagcttccg
    18301 ggcagtggaa ggtggctcga ctgcgctttc ctgggggtgc gtgctgatgc atcgtggact
    18361 gctcgccatc cccgcgtgtc tggctgcggc cacgggtgtg ctggcggcca gcccgtcggc
    18421 ggcggctgac gaacctcacg atgatggcca ggtcgtcgtg acgccggtgg acccgtatgg
    18481 tcagtacacg ccaccgcggg tggatctgcg ggcgttgtac tcgcgcggcg aggcgccgat
    18541 ccgccgcggc ggaccgcagg cgacgtcgtc gcccgggagc ctagcgggca ccgacgggac
    18601 cgggacggcc gacgcgtcga gtggtctgcc gccgggctgc ttcctgggtg ggttccccgt
    18661 tggtgacggc ccgggaggta tccggtcggg cggcaatgcg gtggggctgc ggtgtctgcc
    18721 gtccgtgccg gcggatgccc cgccgggggc gcaggctccc ggcccaccac ccttgccgac
    18781 tccggcagag ctggccgcga gagcgttcga gcagcttcgt cttcctttgc cggtgccgcg
    18841 gcattcgccg gatgtgcggt tgccggatgg gcgggacgcc acgatcgttg gggagaacac
    18901 ctgggtgtgg accgaccgga gcgtgtggca tccggcggtg cagcgggtgc aggtgggtcc
    18961 cgtctgggcg gaggtgaccg cgacgcctgt ggcgatgttg ttcaactccg gcaccggcgg
    19021 ctcgatgtcg tgtgcgggtc cgggcacgcc gtatgaccgg tcgtacgggc tgcacgctgc
    19081 cagccccgat tgcggttttg tgtacacccg ctcgtcggtc gggcagccga acgaccaggc
    19141 cacggcggag tgggcgatcc agtggtcggt gagctgggtc ggctcggacg gcaccacgga
    19201 ggtcggcggg gacttcccgc agatgagttc gcgggccgcg gccacgttcg cggtggccga
    19261 ggtgcaggcc ctgcgcgcga actgacggac aggactttga caaccgcatt ctgcgacaga
    19321 ttcgtttctc gcattctgcg gaaataaagg caacaacatt tttggaatgg ggaaggagtt
    19381 accccagtgg gtactgctgt gtctttttcc cggccgccac agccgcgcag cggcgactcg
    19441 gggctcaccg gccagggcga ggagggcgat ggcccgcggg tgccccggcg gcgccgctgg
    19501 tggctgctgg gcgtcgcggt cgtgctggcc gcggtggtcg cgtacggcaa ccacgcgctg
    19561 atcgcggggc aggacgagcg ggtcgacgtg ttggtgctga cccgcgacgt cgggtggggc
    19621 cagcggatcg gcgaaggcga tctcggcgta gccaaggcgg tcccggacca gcggctggcc
    19681 tccatccccg ccagcgaccg agccggggtg gtcggccagg tcgcgcgctc gacgctgcct
    19741 gcgggcaccg tgctcgcccc cggccagctg tccgcgcagc cggttcccgg gccgggcgag
    19801 cgcctcgtcg ggctgccggt gaaaccgggg cacctgcccg cccgcgggtt ggcacccggc
    19861 gacctggtcc aggtgacccc ggtcgcggga ggcaccggaa ccgatgcgag ccaatccacg
    19921 gcgagcacgg ccgggccgtt tcgcgcgcgg gtgctcgggg ttggcccgcc ggactccacc
    19981 ggcgcggtca cggtcgatgt cctggtcggc gcggacaccg cgcaggccgc aagcagcgcc
    20041 gccgcgggcc aggtggtcct ggtccagctc ggtcccggcg cctaaaagac gactgctgtc
    20101 tggaagggcg gtgagggtgt tggcaatgat cacgatcgtc tcgggcaagg gggcacccgg
    20161 cgcgaccacg acgttggccg cgctggcggc ggcctggccc gtaccggtgg tgttggccga
    20221 ctgcgaccca gccgggggcg acctcgcagc gggctggctg ggccagtggg tcgtggacgg
    20281 cacgatccgc actgacctcg gcgtgttgtc gcacgccacg gcgacccggc acgcgacggc
    20341 gggcgacccg gccacgctgc tcgaccacgt acagcaggtt cctccggccc ggcacgtcgg
    20401 gctgctggcc gggttgagcg cgccgggcca gcacgccgcc gtcggcaccg ccgggtggac
    20461 gcgcctgacc gcggcgctgg ccgcgttcaa gaccacgtcc gggcacccgg ccgacgcgct
    20521 ggtcgacatc ggccgctaca gcacgctcac cccatggccg ctgctgctgg ccgccgacct
    20581 cgtgctggta gcggtacgcc cgacccagcg gcacatcctg gccgcacgcc cgctgctggc
    20641 cgagctcgcc gagcggatcg tcccgcaccg gctcgggttg gcggtctgcg cgacgactcc
    20701 ggcgggcagc cgggaagtcc gcgcggcgct gggccgggag gcgggcgtgc aggtcgctgc
    20761 ggatgcgcgg gcggcggcgg tgttctccga cggcgccgac ggcggcacgc tgccacgccg
    20821 gtcgccgttg ctgcgcagcg tgcgccgcgc ggcgcgccgc ctgcacggca cctaccacca
    20881 ggacaccccg gcggaactgc gcacaccggc cgcaccgggc tcgccgggcg tgctcaccgg
    20941 aggagcccga tgacgttgcc gcacaacggg taccgcccca ccaccggccc cacggccccg
    21001 cgtcgcccgc ccgacctgtc ggcaccgttc gctggtgccc tgggaaccgg gccagcagcg
    21061 ccgccagcgc ccacagcacc gccggacggg gcgacgggcg gctacctgga cccgcaggcc
    21121 gtgcgggcga tccgggagtc ggtcgccgcc cgcctggaac aggtcgccgc cggggaagca
    21181 catttggact cgccgctgtc ggtcgaggag cagcaagccc ggatgcgcgc ctacgtggcc
    21241 gaggaagtca cggcctgggt acaacgtcgc gccgccgcgg gccaggcgcc gctgccagtc
    21301 gacgacgaac ggcggctcgt gcgcgcggtg gtggccgcgc tgtccgggct cggcgcgttg
    21361 gaggagctgc tggagcgcga ggacgtggag aacatccacg tccacggctg cgaccacgtc
    21421 ttcctcgaac tcgcggacgg ctcgatcgaa cggtggccgc atccggtcgc cgacaccgac
    21481 gccgagctgg tcgagatgct cgcggcgatg ttcgcccgcc agggccaaac cagccgggag
    21541 ttcaacgccg gtcgcccgat ggggaacttg cggattcctg ccggtggccc gctcggggcg
    21601 cgggtggcgg cggtgatgga ggtgtccgac cggccgcggg tggcgatccg ccgccaccgc
    21661 ctggtcaacg tcggcctgga cgacctggtc gcgaacggca ccctcgaccc gctgctcgcc
    21721 tccttcctgc gtgcagccgt gcgcgcgggc tgcaacacgg tcgtctccgg tggccccgct
    21781 gccgggaaga ccaccatgtt gcgcgcgttg tgccgcgaga tccccgcctt cgagcacgtg
    21841 gtcaccgtcg aggaggagta cgaactcggc ctgcacatcg gcccccggcc gttggtcact
    21901 ccgctggaag cgcgcccagc gaactccgag ggcatcggcg agatcaccct agacgacctg
    21961 ctcaagcaga cgctgcggca ctcgccgagc cgcgtgatcg tcggcgaagt tcgcgccgga
    22021 gaagtcaccg ccatgctccg cgcgctcggg aacggggcga ccgggggcat gtgcaccctg
    22081 cacgcgatct ccgcgtcggc ggtgttcgac cggatcggcg cgctcgggca actcgccgat
    22141 ccacccctgg ccatcgacgc agcgcaccaa tggaccgcct cggcgatcga cctcgtcgtg
    22201 cacgtcgccc gcaccgacca tcccgggcgc cgggagcggt tcattgccga agtgatcgag
    22261 gtcggcccgg tcggcgattc cggccgcccg gacaccaccc ggatcttcgg cccccgcccg
    22321 gtggacgggc gcgccgtgcc tgcctacgca cccagccgcg acctgctgga gcggctggaa
    22381 cgccacggct tcgaccgcgc cgcgctcgac gccgccggtt ccggcacctg gcacaccgct
    22441 ggtttcccag atgcaggtct gcgatgacga ccgtgtggcc gtggctgctc ggcctggcgg
    22501 cggtgctggc ggtggcctgc gccgtggccg cgttcctgcc gctcgccgcg cggcagcccg
    22561 acgagtccgc tcgagcaacc acgccatggg ggttgcttgc ttggcgagca gtcgtcgcac
    22621 gggttccgct gcgccgggtg ttgctggccg tggccgcagg cgctgtggtg tggtgggcca
    22681 ccggctggcc ggtcgccgcg atcatcgccg ccgccggagt gatcacggtg ccgatcctgg
    22741 cccgcggaca cgacgcgcag cggctcatta cccggctcga cgcgttggca agctgggtgc
    22801 ggcgcctggc cgacgtactc gcctccggcg ccggtggcct ggagcaggcg atcgccagct
    22861 ccgcgcgcac cgcacccgag gcgctcgcca cggaagtgga gaccctggcg gtgcggctgc
    22921 gcacccgcgg cctggagcag gcgttgcgcg cgttcgccga ggacgtcggt gacgaggccg
    22981 ctgacgaggt ggtccttgcg ctgatcttgc gctcgcgggc gggcgggcgt ggcctggtcg
    23041 acatcctcga cgccaaagcc accgctctgg aacgggaagt ggtggcgcgc cgggacatcg
    23101 aagccgaccg cgccaaaccc cgcaccgacg ttcgcgcgat cctcggcatc accgccgtcc
    23161 tgttggccgg gctggtgttc ttcgcccacg agttcctcac cccgttcaac gatgtgctgg
    23221 gtcagctggt gatggccggg atcggcggac tcctgggcgc ggccgggtgg tggatgcacc
    23281 tcctgacccg aactcgccgc ccggcgcggc tgctcggcgc ggcctcgcgc accccggtgg
    23341 gggcaccgaa accgacgcgg aaggcggccg tggtcgcccc ggccggggag ggggtgccgc
    23401 gatgagcccc ggcttcaccg ctgcggtgct gggcgcgctc gcagggctcg cggtcgtgtg
    23461 cgtgatcctg gctctggtac gcccggcccc ggtcaacctg gccgccgcgg tcgccgagct
    23521 ggacgaccgc accgctcgcc gcgccgacgg cgctccgcca aggggccggt gggcgacgcg
    23581 gctggagcac ctcgccggct actcggctcg gtcatcgagc cgctggtggg gcatccccac
    23641 cgccgacctc gacgtactcg accacacgcc cgaacgctat gtcgcccgcc gcctggcctg
    23701 ggccgcaggc gccaccgcgg ccgttctcac ggtgacgggg ctggcgtggt tcgcccggct
    23761 cggctttccc accaccgtgg tggtgctggc cgccgtgatc gcagccgtgg cgggatcggt
    23821 ggtgccggtc ctggccgtgc gcgaggacgc cacccgggca cgggaggagt tccgccgcgc
    23881 gactgcggcc tacctcgacc tcgtggccca ggaacgagcc accggccgtg cgccgagtca
    23941 agcgctaggc gaagccgccg cggtcggcga ttcctgggtg ttcgcccgga tcagccgcac
    24001 gctcggccgc gcgatgcgcg ccgggcacac cccctgggtt gccttgtccc ggttgggaaa
    24061 gcggatgggc gtggtcgaac tcgccgacct ggccgacatc ctcg
//
