LOCUS       NZ_SWMS01000009        22014 bp    DNA     linear   CON 10-DEC-2024
DEFINITION  Prauserella endophytica strain CGMCC 4.7182 Scaffold9, whole genome
            shotgun sequence.
ACCESSION   NZ_SWMS01000009
VERSION     NZ_SWMS01000009.1
KEYWORDS    WGS; RefSeq.
SOURCE      Prauserella endophytica
  ORGANISM  Prauserella endophytica
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Prauserella; Prauserella
            coralliicola group.
REFERENCE   1  (bases 1 to 261856)
  AUTHORS   Liu,J.M., Habden,X., Guo,L., Tuo,L., Jiang,Z.K., Liu,S.W., Liu,X.F.,
            Chen,L., Li,R.F., Zhang,Y.Q. and Sun,C.H.
  TITLE     Prauserella endophytica sp. nov., an endophytic actinobacterium
            isolated from Tamarix taklamakanensis
  JOURNAL   Antonie Van Leeuwenhoek 107 (6), 1401-1409 (2015)
   PUBMED   25832628
REFERENCE   2  (bases 1 to 261856)
  AUTHORS   Li,Q.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-APR-2019) Yunnan Institute of Microbiology, Yunnan
            University, No. 2 Cuihu North Rd, Kunming, Yunnan 650091, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 10.16x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_005146945.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 16:32:08
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,852
            CDSs (total)                      :: 7,795
            Genes (coding)                    :: 7,703
            CDSs (with protein)               :: 7,703
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 34 of 92
            Pseudo Genes (incomplete)         :: 69 of 92
            Pseudo Genes (internal stop)      :: 2 of 92
            Pseudo Genes (multiple problems)  :: 13 of 92
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 18:09:25
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 108382
            Orig. end                         :: 130396
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            SWMS01000009.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22014
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="redox-cofactor"
                     /region_number="1"
                     /rules="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /tool="antismash"
     cand_cluster    1..22014
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(PF04055 and (TIGR04085 or SPASM))
                     and (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /kind="single"
                     /product="redox-cofactor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22014
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12014](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12014
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
     misc_feature    160..175
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.95"
                     /tool="antismash"
     misc_feature    441..452
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.72"
                     /tool="antismash"
     gene            complement(502..2661)
                     /locus_tag="FCN18_RS17885"
                     /old_locus_tag="FCN18_17885"
     CDS             complement(502..2661)
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005441792.1"
                     /locus_tag="FCN18_RS17885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_17885"
                     /product="transglycosylase domain-containing protein"
                     /protein_id="WP_112265004.1"
                     /transl_table=11
                     /translation="MRMRDGLLKMLGLCLLAGVLVAGILFPVVGGMGVLSNQASDTVEA
                     MSTGLADEPPPLVSTITDRDGQPIATLYDQYRIPTAPDQISDAMKWALISVEDRRFYEH
                     HGVDWKGTIRAAISNTSGGDTQGASTLTQQYVKNYLINVIYRGDKLGQQRAQEVTIARK
                     LNEARIAIQLETKMGKEQILAGYLNVVEFSREIYGVGGAARAYFNTTPDKLTVAQGALL
                     AGMANNPPAYDPWNNPERATERRNFVLDKMVENRKLSPQDAERIKAEPLGVVPEGPNKP
                     AANCVGAGPEHGFFCQYVEDYLLEHGMTKEDLYTGGYTIRTTMDPRSNHLAKQSAEEQV
                     DKMEDNVANTLSLVKPGKDRHEVVALAANRDYGPDAEAGQTEYALPSAISNVTGAGSSY
                     KMFTAAAAVERGVVGIYDTVQSPPSHVSQIFSGSPPPCPYIAPYTRGYCVVNASEGYSG
                     SMSLQTALQTSPNTAFVILEEQTGMGPIVEMASKLGLRKTMASNAATGGPPDPNAESQE
                     VRLSQTQFFGPSERSPGKGSFTLGVSPTSGLELANVAATLMSGGVWCPPTPIGEIRDRS
                     GNPVPIKEEPCEQAVPEGLANTMVVGLSKDDLPGGTAAAAAQGVGWSRPMIGKTGTTQN
                     NGSAAFIGATPQIAGASMVFRPDLPNGGLVDGGPGNVIAVDGDSGNMFGGKTPARTWFG
                     AVSKILEGQPAPPLPPADPKYERVN"
     misc_feature    complement(2743..2760)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.56"
                     /tool="antismash"
     misc_feature    complement(2754..2770)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 18.12"
                     /tool="antismash"
     misc_feature    2759..2772
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.34"
                     /tool="antismash"
     misc_feature    complement(2765..2774)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.63"
                     /tool="antismash"
     gene            2952..3245
                     /locus_tag="FCN18_RS17890"
                     /old_locus_tag="FCN18_17890"
     CDS             2952..3245
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005441790.1"
                     /locus_tag="FCN18_RS17890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_17890"
                     /product="WhiB family transcriptional regulator"
                     /protein_id="WP_112265002.1"
                     /transl_table=11
                     /translation="METNQSDWRIYAYCRDTDPDGLFVRGAEQNRAKVVCMGCPVRTEC
                     LAEALDNRIDFGVWGGMTERERRALLRRRPEVGSWRDLLESAKREYEPAAGA"
     gene            complement(3264..4400)
                     /locus_tag="FCN18_RS17895"
                     /old_locus_tag="FCN18_17895"
     CDS             complement(3264..4400)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005441789.1"
                     /locus_tag="FCN18_RS17895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_17895"
                     /product="ArsA family ATPase"
                     /protein_id="WP_137095658.1"
                     /transl_table=11
                     /translation="MTFPTSSLDVDTLIDDPETRVIVCCGSGGVGKTTTAAALALRAAE
                     RGRQTVVLTIDPARRLAQALGLRELGNHPRKVSVAGFEPKGELWAMMLDMRRTFDDMVR
                     RHAGPERSEQLLANRFYQTISTSFSGTQEYMAMEKLGQLAAAGDWELIIVDTPPSRSAL
                     DFLDAPTRLSAALDGRMIRLLTGPAKAGGWGLRKVVSAGFSMFAKAVSTILGGQLLADA
                     SAFMQAFDTTFGGFRERARKTAELLRSKGTAFLVVAAPEPDALREASYFVERLSEESMP
                     LAGLVANRTHPVLADLSAIDALAAADALDRGGRSAPLAAAVLRLHADRVALAEREKRLL
                     ARFTRAHPGVSVVRVPALPSDVHDLAGLREIGDRLAGS"
     gene            complement(4397..5398)
                     /locus_tag="FCN18_RS17900"
                     /old_locus_tag="FCN18_17900"
     CDS             complement(4397..5398)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017985510.1"
                     /locus_tag="FCN18_RS17900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_17900"
                     /product="ArsA-related P-loop ATPase"
                     /protein_id="WP_112264998.1"
                     /transl_table=11
                     /translation="MTTPAGWTDELTRTRLHFVTGKGGTGKTTLAASLGLALASHGRRV
                     LLIEVEGRQGFAQVFDTEPLPYAEQRIAAAPGGGEVRALHIDVEAALLEYFEMFYNLGF
                     AGRTLRRMGAIEFATTLAPGLRDVLLTGKIKECVGRTESDGRHTYDAVVVDAPPTGRVV
                     KFLDVTKALTDLAKTGPIRAQAEGVVRLLHSGETAVHLVTLLEEMPVRETLDAVAELDG
                     ADLRPGAVLINRVRPPRLPARSVPAAADGRVDASRVRGGLASAGLELPEATLDGLVEET
                     VEHAIRLAAEQRAREQLSESDLPTLELADLNGGVDVAALYELAEALVEQGVR"
     gene            complement(5436..5684)
                     /locus_tag="FCN18_RS17905"
                     /old_locus_tag="FCN18_17905"
     CDS             complement(5436..5684)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019809272.1"
                     /locus_tag="FCN18_RS17905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_17905"
                     /product="hypothetical protein"
                     /protein_id="WP_112264996.1"
                     /transl_table=11
                     /translation="METWRILATILLAVAGVAGVLIIMAKARDSTDSSPTVAVAGLVSF
                     TTVAVLCVLTLTVLPGAVAWGVAGLVTLVVTVLTLAS"
     gene            5717..5878
                     /locus_tag="FCN18_RS17910"
                     /old_locus_tag="FCN18_17910"
     CDS             5717..5878
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020642049.1"
                     /locus_tag="FCN18_RS17910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_17910"
                     /product="DUF4177 domain-containing protein"
                     /protein_id="WP_003068074.1"
                     /transl_table=11
                     /translation="MSATKWEYATVPLLIHATKQILDQWGEDGWELVTVLPNPSGEQHV
                     AYLKRPKG"
     gene            5883..6338
                     /locus_tag="FCN18_RS17915"
                     /old_locus_tag="FCN18_17915"
     CDS             5883..6338
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007026588.1"
                     /locus_tag="FCN18_RS17915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_17915"
                     /product="RidA family protein"
                     /protein_id="WP_113641267.1"
                     /transl_table=11
                     /translation="MSWSARLADLGIELPGVAAPVAAYIPAIRSGSLVFTSGQLPFVEG
                     SLAATGKVGGEVSPEEAKQHARTAVLNALAAVHDLVGIDSVVRVVKVTGFVASSEGFTG
                     QPAVINGASELLGEVFGDEGRHARSAVGVAELPLGAPVEVELTVEVS"
     gene            6338..6967
                     /locus_tag="FCN18_RS17920"
                     /old_locus_tag="FCN18_17920"
     CDS             6338..6967
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005441780.1"
                     /locus_tag="FCN18_RS17920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_17920"
                     /product="hypothetical protein"
                     /protein_id="WP_112264993.1"
                     /transl_table=11
                     /translation="MDPDIEYACHELLLRLAGRMPDQMLWRFRDWLGEGAMGTLSRTLP
                     KSLLKHRIDLDQAEYRLLVAGLIPHGADWHQVSSTLGVDASAENRYTFTTGAPDWVNTV
                     DSVSVVVHATLRGRPDVGEVRESWRHDRGSEDEAKRILLVTAVSGLPRLTGELQRVLRV
                     LGDEAPSVEVLPVQFDVPAYHRAALENSRFVCVGSVDAGHHKLVPA"
     gene            7004..8137
                     /locus_tag="FCN18_RS17925"
                     /old_locus_tag="FCN18_17925"
     CDS             7004..8137
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017985506.1"
                     /locus_tag="FCN18_RS17925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_17925"
                     /product="hypothetical protein"
                     /protein_id="WP_112264991.1"
                     /transl_table=11
                     /translation="MVDVHDGLPKDGFAVPLRLHNVLLALAGRLDDSALSEARELVARS
                     HLDDAAELAVGALISGRIMVRPAEQRELALVLEMSRSDATLADQLTVGDAIPGYAHRFS
                     RENEPERGISEALDRTLQVLPDLRSVHAVWRNTPAGSVPGPLPQRVVLVEIGPEAHPPA
                     VAFRVDDALRKGGIRSVVEVTGPGAERTEYHEAALAAATPVWLATGQSAGGSASWSARG
                     PRPVGGAHTVAEAPTPREPSHAAPDFEEPAVKVSTEEKDTGEAPEKEPEPTPAERENRA
                     AATTEMTKEEVAQLRAAIAEDPEKGRAIAAVNLRSDEIVELPELDLDDPQLSDRDRQLL
                     RELHAELAERERAEAAKSAKSRTNGSEHRWADGFSGG"
     gene            8142..8954
                     /locus_tag="FCN18_RS17930"
                     /old_locus_tag="FCN18_17930"
     CDS             8142..8954
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009156590.1"
                     /locus_tag="FCN18_RS17930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_17930"
                     /product="NUDIX domain-containing protein"
                     /protein_id="WP_228714024.1"
                     /transl_table=11
                     /translation="MFRGVPANFHVPKQSVLSLPAEPPERPAAAKDAATVLLLRDAGDG
                     VEVFLQRRVTAMAFAGGMTVFPGGGVDQRDADASVSWAGPPPARWAEWFGCSESVARAL
                     VCAAVRETFEESGVLLAGSESSTVTDTSQYAAAREQLVSRELSLAGFLAGEGLTLRADL
                     LRPWANWVTPEQEPRRYDARFFLAALPEGQHADGRTTEAESSGWSRPADAIADAKAGRS
                     TLMPPTWFLLDELISCASVAEALAQERSVRKITPRLVPDGDAVRVELP"
     gene            8951..9727
                     /locus_tag="FCN18_RS17935"
                     /old_locus_tag="FCN18_17935"
     CDS             8951..9727
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1170: metallo-beta-lactamase family protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020669678.1"
                     /locus_tag="FCN18_RS17935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_17935"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_137095659.1"
                     /transl_table=11
                     /translation="MTHPAYGKLREVSPAASVLLENNPSMMTLEGTNTWVLRAPGSRSC
                     VVVDPGYEDVEHLERVAAVEPVELILLTHHHPDHSEGAPWLAERVGAPVRAFQADLCLG
                     AEPIADDDVVTAAGLEIAVLHTPGHTDDSVSLRFDAAGRTHVLTGDTVLGRGTTVLTDL
                     GHYLRSLKLLCALPEGALGLPGHGPELADLTATAREYSAHREQRLDQVRTALRQLGPEA
                     TPRQVVEIVYADVDPSLWGPAESSVVAQLEYLRSEG"
     gene            9796..9894
                     /gene="pqqA"
                     /locus_tag="FCN18_RS17940"
                     /old_locus_tag="FCN18_17940"
     CDS             9796..9894
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019813815.1"
                     /locus_tag="FCN18_RS17940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_17940"
                     /product="pyrroloquinoline quinone precursor peptide PqqA"
                     /protein_id="WP_110340926.1"
                     /transl_table=11
                     /translation="MVESGELEVWTTPDFEEYETPMEVTAYFGRME"
     misc_feature    9816..9831
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 21.33"
                     /tool="antismash"
     misc_feature    9919..9930
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.34"
                     /tool="antismash"
     gene            10001..10681
                     /gene="pqqC"
                     /locus_tag="FCN18_RS17945"
                     /old_locus_tag="FCN18_17945"
     CDS             10001..10681
                     /EC_number="1.3.3.11"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR02111"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020631254.1"
                     /locus_tag="FCN18_RS17945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_17945"
                     /product="pyrroloquinoline-quinone synthase PqqC"
                     /protein_id="WP_170200566.1"
                     /sec_met_domain="TIGR02111 (E-value: 3.9e-83, bitscore:
                     272.4, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEQAFVAALKGLSHRYWGTHPFHHRMHAGELTEHELRVWAANRW
                     YYQRMLPQKDAAIISNCPLPEVRRQWLDRIVYHDGRAEGEGGAERWLRLCSAVGLDREE
                     VLDERHVAPGVRFAVDAYVNFARTRPWAEAVASGLTEMFSGHLMRRRVGDMLARYEWIR
                     SEDLAYFTNRIDAVSGEGEETLAIVVAHCVTREQQEAAVAALSFKCDVLWSMLTAIEHA
                     AAKQ"
     gene            10678..10929
                     /gene="pqqD"
                     /locus_tag="FCN18_RS17950"
                     /old_locus_tag="FCN18_17950"
     CDS             10678..10929
                     /GO_function="GO:0048038 - quinone binding [Evidence IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005464292.1"
                     /locus_tag="FCN18_RS17950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_17950"
                     /product="pyrroloquinoline quinone biosynthesis peptide
                     chaperone PqqD"
                     /protein_id="WP_137095660.1"
                     /sec_met_domain="PqqD_RRE (E-value: 1.2e-22, bitscore:
                     73.4, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 8e-13, bitscore: 42.5,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPRLRCGVRLTYDRTRQTHVLLFPEGVLVPNATAAAVLELCDGE
                     RTVPDIAAALGERYAGVREGDVGDVLARLVDRQVVEWA"
     aSDomain        10681..10920
                     /aSDomain="PqqD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing protein in a pyrroloquinoline
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_FCN18_RS17950_PqqD_RRE.1"
                     /evalue="1.40E-23"
                     /identifier="RREFam006.1"
                     /label="FCN18_RS17950"
                     /locus_tag="FCN18_RS17950"
                     /protein_end="81"
                     /protein_start="1"
                     /score="73.4"
                     /tool="antismash"
                     /translation="TPRLRCGVRLTYDRTRQTHVLLFPEGVLVPNATAAAVLELCDGER
                     TVPDIAAALGERYAGVREGDVGDVLARLVDRQVVE"
     gene            10920..12014
                     /gene="pqqE"
                     /locus_tag="FCN18_RS17955"
                     /old_locus_tag="FCN18_17955"
     CDS             10920..12014
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_process="GO:0018149 - peptide cross-linking [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: SPASM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019813812.1"
                     /locus_tag="FCN18_RS17955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_17955"
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqE"
                     /protein_id="WP_137095661.1"
                     /sec_met_domain="PTHR43273 (E-value: 1.6e-30, bitscore:
                     100.3, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 7.4e-20, bitscore: 65.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 8.1e-07, bitscore: 23.4,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 6.7e-13, bitscore:
                     42.9, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 2.8e-12, bitscore: 41.0,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGVTEEVQGVRPPLGMLAELTHRCPLHCPYCSNPVELVTRERELG
                     TEEWCSVLDQARDLGVLQVHLSGGEPLARPDLPELVTRASGLGCYVSLVTSGLGLTEAR
                     LADLVDRGLAHVQLSVQGADAARANLLAGAKAHDHKLTAAALVKRFELPLSVNVVLHRA
                     NHDQLEGMIALAERMGADRLELANTQFYGWALRNRDALLPTREQLAAAEPVVRAAIERL
                     KGSMQVVYVLSDYYEQYPKPCMSGWGAQQLTVAPDGTVLPCPAATAITTLPLENVRERP
                     LAEIWYDSESFNAYRGEDWMREPCRTCERRTVDFGGCRCQAFQLTGDAAATDPVCRRSP
                     DRGLVDVLLEPPHGSGEFVMRGVR"
     gene            12011..12892
                     /gene="pqqB"
                     /locus_tag="FCN18_RS17960"
                     /old_locus_tag="FCN18_17960"
     CDS             12011..12892
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020631257.1"
                     /locus_tag="FCN18_RS17960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_17960"
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqB"
                     /protein_id="WP_137095662.1"
                     /transl_table=11
                     /translation="MKVILLGTAAGGGVPQWNCACANCEAVRDGSAPARTQDCLAVSAD
                     GRAWYLLNASPDVRTQLTSCAALAPGPGPRETPLRGVLLTDGELDHTLGLFQLKEAAGL
                     RVWAPGAVAATVPAREIAGRYHGWEWPRLRERFELDGLVVTVFPVSGKRPKYAGDSTLD
                     GPWVVAYRIEDPATGGSLVYAPCVAQWPAGFDEFCAGASCVLLDGSFFAPDEMAGATAG
                     GVGSGAQLAMGHLPMAGEHGSLARIRRSRGTRWLYTHVNNTNPVLNPASPEHAALLEAG
                     AELPPDATELLL"
     gene            complement(12914..14170)
                     /locus_tag="FCN18_RS17965"
                     /old_locus_tag="FCN18_17965"
     CDS             complement(12914..14170)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016337881.1"
                     /locus_tag="FCN18_RS17965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_17965"
                     /product="MFS transporter"
                     /protein_id="WP_206077933.1"
                     /transl_table=11
                     /translation="MSQSESHGRTTLADYRIALSTPGARRPMVASLFARLPIAMIGISA
                     LLFVQRETGSFAAAGLVSAGALVGVSAGSVVQGRIIDRFGPTRPLLLVAALFSVAMTIL
                     VLAIEAHAPTPLLVTLAVGIGVTEPMTGSASRALWARLVPEGPTRDAAFSYEAISMETF
                     FILGPGLAGLLIAAPWPGTGMVLGAACMVTGAVLFALSPAVRAWGPAEERTGGRLLGAL
                     ASPGMRTLALAALGFGMVIGFVEVAVPAAAEEAGHLALGGLLLSAWSVSSVGFGVAYSL
                     RPWPRPMRLRLPVLLALFGALVALLALPTTLWALAIAMLGAGALITPQSTAHSTAIEIV
                     APKGTAAEAFGWVLTAVTLGLAFGQSVSGYLVEHSGPPAAFLAAAACALALAAVVWLLR
                     HTIRPPRPVKPKPTAPALT"
     misc_feature    14201..14216
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 16.99"
                     /tool="antismash"
     misc_feature    complement(14221..14241)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.04"
                     /tool="antismash"
     gene            complement(14544..15218)
                     /locus_tag="FCN18_RS17970"
                     /old_locus_tag="FCN18_17970"
     CDS             complement(14544..15218)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0030552 - cAMP binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003873299.1"
                     /locus_tag="FCN18_RS17970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_17970"
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="WP_005441764.1"
                     /transl_table=11
                     /translation="MDETLARAGIFQGVEPAAAEALAQTLETVEFPRGHVIFNEGEPGD
                     KLYIIKSGKVKIGRKSADGRENLFQIMGPSDMFGELSIFDPGPRTSTATTVTEVSAVTM
                     DRPALRQWISTRPEIAEQLLRVVARRLRRTNNMVAELIFTDVPGRVARALLQLAQRFGS
                     QEAGLLRVTHDLTQEEIAQYVGASRETVNKALADFAHRGWLRLEGKSVLILDPERLARR
                     AR"
     misc_feature    complement(14850..14852)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(15230..15248)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.95"
                     /tool="antismash"
     gene            complement(15492..15743)
                     /locus_tag="FCN18_RS17975"
                     /old_locus_tag="FCN18_17975"
     CDS             complement(15492..15743)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009156587.1"
                     /locus_tag="FCN18_RS17975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_17975"
                     /product="hypothetical protein"
                     /protein_id="WP_110340936.1"
                     /transl_table=11
                     /translation="MTVWFVIAVPLVVMLFALGMERVENRLRHVSVRGEDVEEFLEQAQ
                     PDEVRALYGHGIGRALELFRLRRLGGKTAKLKPRRVRG"
     misc_feature    complement(15728..15743)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.43"
                     /tool="antismash"
     gene            15836..16606
                     /gene="nth"
                     /locus_tag="FCN18_RS17980"
                     /old_locus_tag="FCN18_17980"
     CDS             15836..16606
                     /EC_number="4.2.99.18"
                     /GO_function="GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /gene="nth"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009156586.1"
                     /locus_tag="FCN18_RS17980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_17980"
                     /product="endonuclease III"
                     /protein_id="WP_206077934.1"
                     /transl_table=11
                     /translation="MSSAVGRAPRKRRSFAEESRLSLVRRARRMKRCLDEAYPNAHCEL
                     DFTTPLELLVAVILSAQCTDQRVNLTTPALFARYRTAADYAGADRTELEELIRPTGFYR
                     NKATSLLGLGAALVERHGGDVPGKLDQLVKLPGVGRKTANVVLGEAFGVPGITVDTHFG
                     RLVRRWGWTGDEDPVRVEHEIGELIPRKEWTMLSHRVIFHGRRVCHARKPACGACPLAN
                     DCPSYGAGPTEFDVAAKLVKGPERDHLLSLVTKS"
     gene            16603..17199
                     /locus_tag="FCN18_RS17985"
                     /old_locus_tag="FCN18_17985"
     CDS             16603..17199
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1241: lipoprotein
                     dsbF"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013230549.1"
                     /locus_tag="FCN18_RS17985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_17985"
                     /product="TlpA disulfide reductase family protein"
                     /protein_id="WP_137095663.1"
                     /transl_table=11
                     /translation="MTTATKWALAVGVLALAVLVAVLPNIGDEPAPPRAGEDLGPARSA
                     AALEPCPKGSGTVQRLAGVEASCLGDGSQVDLGSALAGETTLVNVWATWCQPCREELPL
                     LQSYAAEPGAARVLAVQVQSDAKDGLELLAELGVHLPSVHDGEGPTGPVREALRVPRAL
                     PASYLVTEDGQVRFVDDPRLFTSVAQIRETVEAAR"
     gene            17196..17906
                     /locus_tag="FCN18_RS17990"
                     /old_locus_tag="FCN18_17990"
     CDS             17196..17906
                     /EC_number="3.6.1.55"
                     /GO_component="GO:0005777 - peroxisome [Evidence IEA]"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0003986 - acetyl-CoA hydrolase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008413 - 8-oxo-7,8-dihydroguanosine
                     triphosphate pyrophosphatase activity [Evidence IEA]"
                     /GO_function="GO:0010945 - coenzyme A diphosphatase
                     activity [Evidence IEA]"
                     /GO_function="GO:0030145 - manganese ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0035539 - 8-oxo-7,8-dihydrodeoxyguanosine
                     triphosphate pyrophosphatase activity [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0009132 - nucleoside diphosphate metabolic
                     process [Evidence IEA]"
                     /GO_process="GO:0015938 - coenzyme A catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016337878.1"
                     /locus_tag="FCN18_RS17990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_17990"
                     /product="CoA pyrophosphatase"
                     /protein_id="WP_112264975.1"
                     /transl_table=11
                     /translation="MTGPLVDPGDVPEWLRGLVEVSGELDAKTFTRFAAPSGTRTRSAA
                     VLILFGDGGERGPDVLLLRRADTLGSHAGQVAFPGGGAEDGDDGPVGTALREAEEETGV
                     VPSGVRPLAVLPELYVPVSGFAVTPVLAHWREPCPVHAVDPAETAAVARVPVAELTDPA
                     NRFLVRRSGADWKGPAFEVGEMFVWGFTAGLLSVLLTLGGWEREWDHTDVRDLDVALAR
                     HEARVRRAEAGSRE"
     misc_feature    complement(17916..17929)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 21.28"
                     /tool="antismash"
     gene            17916..19100
                     /locus_tag="FCN18_RS17995"
                     /old_locus_tag="FCN18_17995"
     CDS             17916..19100
                     /EC_number="3.4.21.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007035061.1"
                     /locus_tag="FCN18_RS17995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_17995"
                     /product="MarP family serine protease"
                     /protein_id="WP_112264973.1"
                     /transl_table=11
                     /translation="MNWVDVLVILLALLAAVSGARQGVVIALPAFLGVIAGAVVGIQLA
                     PMVVDFFDHPAARVAFAVGTVVFLVALGETLGVWLGNKLKSRIRSPKLSGVDSSLGAVV
                     QGVVVFVVAWLIALPLTSVAALPGLARAINNSVVLGGVNSMMPDAAQGLPGELRQLLDA
                     SGFPSIVDPFQKAPVRETGPPDAALQNSAVVQDLRPSVLKIRGIAPSCSRSLEGSGFVV
                     SPERVMTNAHVVAGTEEVAVETDAGRLDARVVYYDPETDLAILAVPGLTAAPLALDPQP
                     AQEGDDAIALGYPLDGPYTASALRVRQRINLRGPDIYDANTVERDVFTVRGQVRSGNSG
                     GPMVDPDGDVIGVVFGASVEDPETGFVLTADEVRAEVEAAPGLGAQVSTGPCTS"
     gene            complement(19162..20109)
                     /locus_tag="FCN18_RS18000"
                     /old_locus_tag="FCN18_18000"
     CDS             complement(19162..20109)
                     /NRPS_PKS="Domain: Abhydrolase_1 (36-297). E-value:
                     1.8e-33. Score: 108.1. Matches aSDomain:
                     nrpspksdomains_FCN18_RS18000_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020669686.1"
                     /locus_tag="FCN18_RS18000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_18000"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_137095715.1"
                     /sec_met_domain="PF00561 (E-value: 1.2e-26, bitscore: 87.8,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.2e-24, bitscore:
                     81.2, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPAPDPSTVRLVGPWTHRDVSANGIRLHVAEAGSGELVLLLHGFA
                     EFWWTWHHQLRSLSEAGFRVVAADLRGYGDSDKPPRGYDAWTLAGDVAGLVRALGERRA
                     HLVGHAWGGLLAWTAATLHPRVVSSVSVLGGAHPLALRSAFGRSALRRRRSQARAMSHL
                     LRFQMPMRPERWLVKDDAAAVERLLHDWSGETWRRGPGFAETARAFRNAMLVPGVAHSA
                     LEYYRWAFRAQFRGEGRRFAEAVDARLRMPVLQLHGAADPVVLPGTAHDSAPWLGPRSR
                     FETMPRVGHYPQLEEPENTAKALVSFLRGSGQPQ"
     aSDomain        complement(19219..20001)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FCN18_RS18000_Abhydrolase_1.1"
                     /evalue="1.80E-33"
                     /label="FCN18_RS18000_Abhydrolase_1.1"
                     /locus_tag="FCN18_RS18000"
                     /protein_end="297"
                     /protein_start="36"
                     /score="108.1"
                     /tool="antismash"
                     /translation="LVLLLHGFAEFWWTWHHQLRSLSEAGFRVVAADLRGYGDSDKPPR
                     GYDAWTLAGDVAGLVRALGERRAHLVGHAWGGLLAWTAATLHPRVVSSVSVLGGAHPLA
                     LRSAFGRSALRRRRSQARAMSHLLRFQMPMRPERWLVKDDAAAVERLLHDWSGETWRRG
                     PGFAETARAFRNAMLVPGVAHSALEYYRWAFRAQFRGEGRRFAEAVDARLRMPVLQLHG
                     AADPVVLPGTAHDSAPWLGPRSRFETMPRVGHYPQLEEP"
     CDS_motif       complement(19747..19797)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FCN18_RS18000_0001"
                     /evalue="3.40E-03"
                     /label="NRPS-te1"
                     /locus_tag="FCN18_RS18000"
                     /protein_end="121"
                     /protein_start="104"
                     /score="10.0"
                     /tool="antismash"
                     /translation="HLVGHAWGGLLAWTAAT"
     gene            complement(20130..20645)
                     /locus_tag="FCN18_RS18005"
                     /old_locus_tag="FCN18_18005"
     CDS             complement(20130..20645)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007028454.1"
                     /locus_tag="FCN18_RS18005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_18005"
                     /product="phage holin family protein"
                     /protein_id="WP_199542483.1"
                     /transl_table=11
                     /translation="MRPVSSPKHEPVGGDRVGSVPYIPLSEENESAADGQSIGALVKDA
                     TAHLSTLFRAEVELVKAETVGEAKKAAKGSVFFVIAGVVALYSSFFFFFFLGELLSEWL
                     QRWAAFGIVFLLMLVTAALFGLLGYRKWKKVRAPQRSIDSLKETAAALKPRREPEPAAA
                     EPGLPAQR"
     gene            complement(20658..21872)
                     /gene="nhaA"
                     /locus_tag="FCN18_RS18010"
                     /old_locus_tag="FCN18_18010"
     CDS             complement(20658..21872)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0006885 - regulation of pH [Evidence IEA]"
                     /codon_start=1
                     /gene="nhaA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009156580.1"
                     /locus_tag="FCN18_RS18010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_18010"
                     /product="Na+/H+ antiporter NhaA"
                     /protein_id="WP_112264970.1"
                     /transl_table=11
                     /translation="MNTSRRPAQAVSEFARFLRVETTGGMLLLAATAIALLWANSPLDD
                     VYRTVRDFRIGPESLHLNLSIGDWAKDGLLAVFFFVAGLELKRELVVGELSNLKSAALP
                     IIAAAGGMIAPALIAVGIAWGEPGIEQAWAIPVATDIAFALGVLALTGSNLPTAARVFL
                     LSLAVVDDLGAIIVIAALFTESFSLVAAAIAVSGLACYAYLQHRRVRAWWIYVPLALVV
                     WASVHAAGVHATIAGVALGLLTRVRADRGEHEAPALRLEHRLQPWSAGFAVPMFALFAA
                     GIAVSADALSAVFTSPIPLAVMAGLLGGKLVGILGFSALAVRLGIARLPGSLTWLDIGA
                     LSMLGAVGFTVSLLIAELSLEGEAAELAKAAVLIASAVASLTAALLLIRRSKVHASGAP
                     TEPSD"
     misc_feature    complement(21980..21997)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.48"
                     /tool="antismash"
ORIGIN
        1 ttgcggcccc tcggcatcag gtacctggcg gggttcttcg gcttgggcgc gtagtagtcg
       61 ttgctgccga acacgaacag gccgggccgg tcgagcagcg ggccgaacgc acgcagcacc
      121 gagggcaccg cccgccggtg ggcgaggttg tcgcccgtgt tgacgaccag gtcgggctcc
      181 agccggtcga gctcggcgac ccagcgctgc ttggagacct ggccgggcag catgtgcagg
      241 tcggagacgt gcaggattct gatcggccgg gctccgctgg ccagtacggg cagctccgcc
      301 gtgcgcagtg tccagtgccg ccgctcgatg tcgacggcgt aaccgagggt tgcggcgccg
      361 agtgccgccg tacccgtcac gagacgtttc atcatcatcc ttgagcgtgc ctgtgttacc
      421 cagcgtacac gcgtgatgca gaaaacgtgt tcgtccgtgg caacgattca gccgatcgtc
      481 gccgatgtgc tcagccgggc ttcagttgac ccgctcgtac ttcgggtcgg ccgggggcaa
      541 cggcggggcc ggctgccctt cgaggatctt gctcacggct ccgaaccacg tcctggccgg
      601 cgtcttgccg ccgaacatgt tgccgctgtc tccgtcgacc gcgatcacgt tgccgggccc
      661 gccgtcgacc agaccgccgt tgggcaggtc gggccggaac accatcgacg cgcccgcgat
      721 ctgcggggtc gcgccgatga aggcggccga gccgttgttc tgggtggtgc cggtcttacc
      781 gatcatcggc cggctccagc cgacgccctg ggccgcggcc gccgcggttc cgcctggcag
      841 atcgtccttg ctcagcccca ccaccatcgt gttggcgagc ccctccggca cggcctgctc
      901 gcagggctcc tccttgatcg gcaccgggtt gccgctgcga tcccggatct cgccgatcgg
      961 cgtcggcggg caccacacgc cgccgctcat caacgtcgcc gcgacgttgg ccagctccag
     1021 gccgctcgtc gggctcaccc cgagcgtgaa cgagcccttg cccggggacc gttcgctcgg
     1081 tccgaagaac tgggtctggc tgagcctgac ctcctggctc tccgcgttcg ggtcgggcgg
     1141 gccgccggtc gcggcgttgg acgccatcgt cttgcgcagc cccagtttgc tggccatctc
     1201 gacgatcggc cccatgccgg tctgctcctc gagtatcacg aaggccgtgt tcggcgaggt
     1261 ctgcaacgcc gtctgcaacg acatgctgcc gctgtagccc tcgctcgcgt tcaccacgca
     1321 gtagccgcgc gtgtagggcg cgatgtaggg acacggcgga gggctgccgc tgaagatctg
     1381 cgacacgtgc gacggcggcg actggacggt gtcgtagatg ccgaccacac cgcgttccac
     1441 ggcggccgcg gcggtgaaca tcttgtagct cgatcccgcg ccggtcacgt tcgagatggc
     1501 cgagggcagc gcgtactccg tctgccccgc ctccgcgtcg ggcccgtagt cgcggttggc
     1561 ggccagcgcc accacctcgt gccggtcctt gcccggcttg accagcgaca acgtgttggc
     1621 gacgttgtcc tccatcttgt ccacctgctc ctcggccgac tgcttggcga ggtggttgga
     1681 cctggggtcc atggtggtgc ggatggtgta gccgccggtg tagagatctt ccttggtcat
     1741 cccgtgctcg agcaggtagt cctcgacgta ctggcagaag aagccgtgtt cggggcctgc
     1801 gccgacgcag ttggcggccg gcttgttggg tccctcgggg accacgccga gcggctcggc
     1861 cttgatgcgt tcggcgtcct gcggcgagag cttgcgattc tccaccatct tgtcgagcac
     1921 gaagttgcgc cgctccgtgg cgcgctccgg gttgttccac gggtcgtagg cgggcgggtt
     1981 gttggccatg cccgcgagca gcgcgccctg cgcgaccgtg agcttgtccg gcgtggtgtt
     2041 gaagtaggcg cgcgcggcac caccgacccc gtagatctcg cgcgagaact ccacgacgtt
     2101 gaggtagccg gcgaggatct gctccttgcc catcttcgtc tcgagctgga tggcgatccg
     2161 ggcctcgttg agcttgcggg cgatggtgac ctcctgcgcc cgctgctggc ccagcttgtc
     2221 gccccggtag atgacgttga tgaggtagtt cttgacgtac tgctgcgtga gcgtggacgc
     2281 gccctgcgtg tcgccgcccg aggtgttgct gatcgccgct cggatggtgc ccttccagtc
     2341 gactccgtgg tgctcgtaga agcggcggtc ctccaccgag atcagcgccc atttcatggc
     2401 gtccgagatc tggtcggggg cggtgggtat gcggtactgg tcgtacagcg tcgcgatcgg
     2461 ttggccgtcc cggtcggtaa tggtgctgac cagcggcggc ggctcgtcgg caaggcccgt
     2521 ggacatggcc tcgacggtgt cgctggcctg gttggagagc acccccatgc ccccgacgac
     2581 cgggaagagg atccccgcga ccagcacccc cgcgagtagg cagaggccga gcatcttcag
     2641 cagaccgtcc ctcatgcgca cccatatcag ggtagccacg agtggcgtat ctcacctgat
     2701 tcgttcactg ggccgagcgg gttgcgttct ccggataccg cattgacagg aatgtgacat
     2761 ctggtaacaa aacgcggctt gggggttggc ggacggaacc gaggccccct acagtccgtc
     2821 aacatctcac gaatacggcg cctggggagg cgctactgga gggacgtgag cacaggagac
     2881 ctgctcgcgg ggggcgaggc cgaggaactt cgctgcctgc ctgcggtcac aacagggtag
     2941 gagctggggg tatggagacc aaccagtcgg actggcggat ctatgcgtac tgcagggaca
     3001 ccgaccccga cggcctgttc gtcaggggcg cggagcagaa ccgggccaag gtcgtctgca
     3061 tggggtgccc ggtgcgcacc gaatgcctgg ccgaggcgct ggacaaccgg atcgatttcg
     3121 gtgtctgggg cgggatgacc gagcgcgagc ggcgcgcgct cctgcgcagg cggcccgagg
     3181 tgggcagctg gcgcgacctg ctggagtcgg ccaaacgcga gtacgagccc gccgcgggag
     3241 cctgaacgct gaagggggcc gcctcagctt ccggccaggc ggtccccgat ttccctcaac
     3301 ccggcgaggt cgtgcacgtc gctgggcaac gccggaaccc gcacgaccga caccccgggg
     3361 tgagcccggg tgaagcgcgc gagcaggcgc ttctcccgtt cggccagcgc gacgcggtcg
     3421 gcgtgcaggc gcaggaccgc ggcggcgagc ggagcgctcc tgcctccgcg gtcgagcgcg
     3481 tcggccgcgg ccagcgcgtc gatggccgag agatcggcga gcaccggatg ggtccggttc
     3541 gcgacgagcc cggccagcgg catggactcc tcggacagcc gctccacgaa gtagctcgcc
     3601 tcccgcagcg cgtccggttc gggcgccgcc accaccagga acgccgtgcc cttcgagcgc
     3661 aacagctccg cggtcttgcg ggcccgctcg cggaacccgc cgaacgtcgt gtcgaacgcc
     3721 tgcatgaacg ccgacgcgtc ggcgagaagc tgcccgccga ggatggtcga cacggccttc
     3781 gcgaacatcg agaatccggc gctgacgacc ttgcgaaggc cccagccgcc cgccttcgcc
     3841 ggtccggtga gcaggcggat catccggccg tcgagcgcgg cggagagccg ggtcggcgcg
     3901 tcgaggaagt ccagcgccga ccggctcggc ggtgtgtcga cgatgatcag ctcccagtcg
     3961 cccgcagccg cgagctggcc gagcttctcc atcgccatgt actcctgcgt gccggagaac
     4021 gacgtggaga tcgtctggta gaagcggttg gccagcagct gctcggagcg ttccggcccg
     4081 gcgtggcggc gcaccatgtc gtcgaaggtg cggcgcatgt cgagcatcat cgcccacagc
     4141 tcacccttcg gctcgaagcc ggcgaccgag accttgcgcg ggtggttgcc cagttcccgc
     4201 aggcccagcg cctgtgcgag cctgcgggcc gggtcgatcg tcagcaccac ggtctgcctg
     4261 ccgcgttccg ccgcgcgcag ggcgagcgcc gccgccgtcg tggtcttgcc gaccccaccg
     4321 gagccgcagc acacgatcac gcgcgtctcg gggtcgtcga tcagtgtgtc cacgtccagg
     4381 ctcgaggtcg ggaaggtcat cgaaccccct gttcgaccag tgcctcggcg agttcgtaaa
     4441 gagcggcgac gtcgacgcca ccgttgaggt cggccagctc gagcgtaggc aggtcgctct
     4501 cggagagctg ctcgcgcgcg cgttgctcgg cggccagccg gatcgcgtgc tccacggtct
     4561 cctcgacgag cccgtccagg gtcgcctcgg gcagctccag ccccgctgac gcgagcccgc
     4621 cgcggacgcg ggaggcgtcg accctgccgt ccgcggcggc gggcaccgat cgcgcgggca
     4681 gcctcggcgg gcggacccgg ttgatcagca ccgctcccgg ccgcagatcg gcgccgtcga
     4741 gttccgcgac cgcgtcgagg gtctcccgta ccggcatctc ctccagcaac gtcacgagat
     4801 gcacggccgt ctcgccggag tgcagcagcc gcaccacccc ttcggcctgc gcgcggatcg
     4861 gaccggtctt ggccaggtcg gtgagggcct tggtgacgtc gaggaacttc accacgcggc
     4921 cggtcggcgg cgcgtcgacc acgacggcgt cgtaggtgtg cctgccgtcg gactcggtcc
     4981 gcccgacgca ctccttgatc ttgccggtca gcagcacgtc acgaagaccc ggcgcgaggg
     5041 tggtcgcgaa ctcgatggcg cccatgcggc gcagggtccg gccagcgaag ccgaggttgt
     5101 agaacatctc gaagtactcg agcagcgcgg cctcgacgtc gatgtgcaga gcccgcacct
     5161 caccgccgcc gggcgcggcg gcgatgcgct gctcggcgta gggcaggggc tcggtgtcga
     5221 agacctgggc gaagccctgt ctgccctcca cctcgatgag cagcacgcgt ctgccgtggc
     5281 tggccagcgc gagtccgagg gaggcggcga gggtggtctt gccggtcccg cccttgcctg
     5341 tgacgaagtg gagccgggtc cgtgtgagct cgtcggtcca gccagccggt gtggtcacct
     5401 aggcagggta agccagaaat cccgatcatc gcggctcagg aggcgagtgt gaggacggtg
     5461 acgaccagcg tgacgagccc ggcgacaccc caggccacgg caccgggcag caccgtgagt
     5521 gtgagcacgc acagcacggc caccgtggtg aaggacacga ggccggcgac ggcgacggtc
     5581 ggcgagctgt cggtgctgtc gcgcgccttg gccatgatga tcagcacgcc tgccacgccg
     5641 gccacggcca gcaggatcgt cgcgaggatg cgccatgtct ccacgcgctc agacggtact
     5701 ggctagggtg tgccgcatga gtgccacgaa gtgggagtac gccacggttc cactgctgat
     5761 ccacgcgacc aagcagatcc tcgaccagtg gggtgaggac ggctgggagt tggtgaccgt
     5821 gctgcccaac cccagcggcg agcagcacgt cgcctacctg aagcgaccga agggctgagc
     5881 ccgtgagctg gagcgcgagg ctcgccgacc tcggcatcga gctgcccggc gtcgccgcac
     5941 cggtcgccgc ctacattccc gccatccgca gcggctcgct cgtgttcacg tcgggccagc
     6001 tgccgttcgt cgagggctcg ctcgccgcga ccggcaaggt cggcggcgag gtgagccccg
     6061 aggaagccaa gcagcacgca cgcactgccg tgctcaacgc gctcgcggcc gtgcacgatc
     6121 tggtgggcat cgactcggtg gtccgggtgg tcaaggtgac cggtttcgtg gcctccagcg
     6181 agggattcac cggtcagccc gccgtgatca acggtgcgtc cgagctgctc ggagaggttt
     6241 tcggcgacga gggcaggcat gcccggtccg ccgtgggcgt cgcggaactg ccgctcggag
     6301 ccccagtcga agtcgagctg accgtggagg tttcctgatg gaccccgaca tcgagtacgc
     6361 gtgccacgag ctgctgctgc ggctggccgg gcgcatgccc gaccagatgc tgtggcggtt
     6421 ccgggactgg ctgggtgagg gcgcgatggg tacgctctcc cgcaccctcc cgaagtcttt
     6481 gcttaagcac aggatcgatc tcgaccaggc ggagtaccgc ctgttggtcg ccggtctgat
     6541 cccccacggt gccgattggc accaggtgag ttcgacgctt ggggtagacg cctccgccga
     6601 gaaccggtac acattcacga cgggtgcacc cgattgggtg aacaccgtcg attcggtgtc
     6661 cgtggtggtt cacgcaacgt tgcgtggtcg cccggatgtg ggagaggttc gggagagctg
     6721 gcggcacgac cgtgggtccg aagacgaggc gaagcggatc ctgctggtca ccgcggtttc
     6781 cggcctccca cgacttactg gggagctaca acgagtcctc cgggtgctcg gtgacgaggc
     6841 gccgagcgtg gaggtcttgc cggtgcagtt cgacgtgccc gcctaccacc gggcggcgct
     6901 cgagaactca cggttcgtgt gcgtgggctc cgtggacgcc ggtcaccaca aactcgtacc
     6961 cgcgtaacgc tcgctcggcc agcgggctgg agggagatcg gcgatggtgg atgtccacga
     7021 tggcctgccg aaggacggct tcgcggtccc gctgcgactg cacaacgtcc tgctggcgct
     7081 ggcgggccga ctggacgaca gcgcgctgtc ggaggcacgt gagctcgtcg ctcgttcgca
     7141 cctggacgac gcggccgaac tcgccgtcgg cgcgctgatc tccggccgga tcatggtccg
     7201 gcctgccgag cagcgtgagc tggcgctcgt gctggagatg agcaggtcgg acgcgacgct
     7261 ggccgatcag ctcaccgtcg gcgacgccat tcccggctac gcccaccggt tcagccgcga
     7321 gaacgagccc gagcgcggca tctccgaggc gctcgaccgc accctgcagg tgctgccgga
     7381 tctgcgctcc gtgcacgccg tgtggcgcaa cacgcccgcg ggcagcgtgc cgggcccgct
     7441 gccgcagcgc gtggtgctcg tcgagatcgg ccccgaggca cacccgcccg ccgtcgcgtt
     7501 ccgcgtcgac gacgcgctgc gcaagggcgg catccgctcg gtcgtcgagg tcaccggacc
     7561 cggagccgag cgcaccgagt accacgaggc ggcgctggcc gcggcgacgc cggtgtggct
     7621 ggccacgggc cagtcggcag gcggctcggc ctcgtggagc gcacgcgggc cgcgtccggt
     7681 cgggggcgcc cacacggtcg ccgaggcgcc gacgccgcgt gagccgtccc atgcggctcc
     7741 cgacttcgag gagcctgccg taaaggtctc caccgaggag aaggacaccg gcgaggctcc
     7801 cgagaaggag ccggagccca ccccggcgga gcgggagaac cgcgccgcgg cgaccaccga
     7861 gatgaccaag gaggaggtcg cgcagctgcg cgccgctatc gccgaggacc ccgagaaggg
     7921 gcgcgcgatc gccgccgtca acctgcgttc cgacgagatc gtcgagctgc ccgaactcga
     7981 cctcgacgac ccgcagctgt ccgaccgcga ccgccagctg ctgcgtgagc tgcacgccga
     8041 gctggccgaa cgcgagcgcg ctgaggccgc gaagagcgcc aagagcagga cgaacggcag
     8101 cgagcaccgc tgggcggacg gcttctccgg cggctgaagg tatgtttcgg ggcgtgccag
     8161 cgaacttcca cgtgccgaag cagtctgtgc tgtcgttgcc ggccgagccg ccggagcggc
     8221 ccgccgccgc caaggacgcg gcgacggttt tgctccttcg cgacgcgggt gacggcgtcg
     8281 aggtcttcct ccagcgccgt gtcacggcga tggccttcgc gggcgggatg accgtcttcc
     8341 caggcggggg tgtcgaccag cgcgacgccg acgcgtcggt gagctgggca ggtccgccgc
     8401 ccgcgcggtg ggcggagtgg ttcggctgct ccgagtcggt ggcgagggcg ctggtgtgcg
     8461 cggccgtccg cgagacgttc gaggagtcgg gcgtgctgct ggcgggctcc gagtcgagca
     8521 cggtcaccga cacctcgcaa tacgcggccg cccgtgaaca gctcgtctcg cgggagctct
     8581 cgctcgccgg cttcctcgca ggcgagggtc tgaccctgcg cgcggacctg ctgcggccgt
     8641 gggcgaactg ggtgacccca gagcaggagc cgcgccgcta cgacgcgcgg ttcttcctcg
     8701 ccgcactgcc agagggccag cacgccgacg gcaggaccac cgaggccgag tcgtccggct
     8761 ggagcaggcc cgccgacgcc atcgccgacg ccaaggcggg ccggagcacg ctcatgcccc
     8821 ccacgtggtt cctgctcgac gagctcatct cgtgcgcgtc ggtcgccgag gcgctggcgc
     8881 aggagcggtc ggtgcgcaag atcacgcctc ggctcgtgcc cgacggtgac gcggtgaggg
     8941 tggagttgcc atgacccatc ccgcgtacgg gaagctgcgc gaggtctcgc ccgccgcctc
     9001 ggtgctgctg gagaacaacc cctcgatgat gacgctcgag ggcaccaaca cgtgggtgct
     9061 gcgggcgccc ggctcccgct cgtgcgtggt ggtggacccc ggttacgagg acgtcgagca
     9121 cctggagcgg gtcgccgccg tcgagcccgt cgagctgatt ctgctcaccc accaccaccc
     9181 cgaccactcc gagggcgcgc cgtggctcgc cgagcgcgtc ggcgcgccgg tgcgcgcgtt
     9241 ccaggccgac ctgtgcctcg gcgcggagcc gatcgcggac gacgacgtcg tgaccgccgc
     9301 cgggctggag atcgccgtgc tgcacacccc cggccacacc gacgactcgg tgagcctgcg
     9361 gttcgacgcg gcagggcgca cccacgtgct cacgggcgac accgtgctcg gccggggcac
     9421 cactgtgctg accgatctcg gacactacct gcgctcgctg aaactgctct gcgcgttgcc
     9481 ggagggggca ctcgggctgc ccggtcacgg gccggagctg gccgacctca cggccaccgc
     9541 gcgcgagtac tccgcacacc gggaacagcg gctcgaccag gtgcgaaccg cgctgcggca
     9601 gctcggcccc gaggcgacgc cgcggcaggt cgtcgagatc gtctacgccg acgtcgaccc
     9661 ctcgctgtgg ggtccggccg agtccagcgt ggtggctcag ttggagtatc tgcggtccga
     9721 gggatagcgc tttcagcgcg aatcccgtta ccgtggtggc gttttcatcg acatcccaat
     9781 ggagggaggc gcaccatggt cgagtcgggc gagctggagg tctggaccac cccggacttc
     9841 gaggagtacg agacgccgat ggaggtcacg gcgtacttcg gccgtatgga gtgacgagtg
     9901 tttcggcgtg gccgatggga aagcgcttac agccgttccg tcggccacgc cccaccgacc
     9961 cgggaggacg gcagtgcggc cgatcgagcc gaagccaccg atgaccgagc aggccttcgt
    10021 cgccgcgctc aagggactct cgcaccgcta ctggggcacc catccgttcc accaccggat
    10081 gcacgccggt gagctgaccg agcacgagct gcgggtctgg gccgccaatc gctggtacta
    10141 ccagcgcatg ctgccgcaga aggacgcggc gatcatcagc aactgcccgc tgccggaggt
    10201 gcgcaggcag tggctcgacc gcatcgtcta ccacgacggc cgggccgagg gcgagggcgg
    10261 agccgagcgc tggctgcgcc tgtgctcggc ggtcggcctc gaccgtgagg aggtgctgga
    10321 cgagcgccac gtcgcgccgg gcgtgcggtt cgccgtcgac gcgtacgtga acttcgcgcg
    10381 caccaggccg tgggccgagg cggtcgcctc cgggctcacg gagatgttct ccgggcacct
    10441 catgcgccgc cgggtcggcg acatgctggc gcgttacgag tggatccgca gcgaggacct
    10501 ggcctacttc acgaaccgga tcgacgccgt gagcggcgag ggcgaggaga cgctcgcgat
    10561 cgtcgtggcc cactgtgtca cccgcgagca gcaggaggcg gccgtggcgg cactgtcgtt
    10621 caagtgcgac gtgctgtggt cgatgctcac cgccatcgag cacgcggcgg cgaagcagtg
    10681 acgccccggc tgcgctgcgg cgtgcggctg acctacgacc gcaccaggca gacccacgtg
    10741 ctgctgttcc ccgagggcgt gctggtgccc aacgcgaccg cggccgccgt gctcgagctg
    10801 tgcgacggcg agcggacggt gcccgacatc gccgcagcgc tcggcgagcg ctacgcgggt
    10861 gtgcgcgaag gcgacgtcgg cgacgtgctc gccaggctcg tcgaccggca ggtggtcgaa
    10921 tgggcgtgac ggaggaggtg cagggggtgc ggccgccgct gggcatgctc gccgagctga
    10981 cccaccgctg cccgctgcac tgtccgtact gctcgaaccc cgtcgaactg gtcacgcgcg
    11041 agcgggaact gggcaccgag gagtggtgct cggtgctcga ccaggcccgc gacctcggcg
    11101 tcctgcaggt gcacctctcc ggcggtgagc cgctggccag gccggacctg ccggagctgg
    11161 tcacccgcgc ttccggtctc ggctgctacg tcagcctcgt gaccagcggg ctcgggctca
    11221 ccgaggcgcg ccttgccgac ctcgtggacc ggggactcgc acacgtccag ctgtccgtgc
    11281 agggtgccga cgccgcgcgg gcgaacctgc tcgcgggcgc gaaggcccac gaccacaagc
    11341 tcaccgccgc ggcgctggtg aagaggttcg agctgccgct gagcgtcaac gtcgtgctgc
    11401 accgggccaa ccacgaccag ctggaaggca tgatcgcgct cgccgagcgg atgggcgccg
    11461 accggctgga gctggccaac acgcagttct acggctgggc gctgcgcaac cgcgacgcgc
    11521 tcctgccgac ccgcgagcag ctcgcggcgg cggagccggt ggtgcgggcg gcgatcgagc
    11581 ggctcaaggg ctcgatgcag gtcgtctacg tgctctccga ctactacgag cagtacccca
    11641 agccgtgtat gtccggctgg ggcgcccagc agctgaccgt ggctccggac ggcaccgtgc
    11701 tgccctgccc cgcggccacg gcgatcacga cgttgccgct ggagaacgtg cgagagcggc
    11761 cgctggcgga gatctggtac gactcggagt cgttcaacgc ctaccgtggc gaggactgga
    11821 tgcgcgagcc gtgccggact tgcgagcggc ggaccgtcga cttcggcggt tgccgctgcc
    11881 aggcgttcca gctcaccggc gacgccgccg cgaccgaccc ggtgtgccgt cgctcgcccg
    11941 accggggatt ggtggacgtg ctgctggagc cgccgcacgg ctccggcgag ttcgtgatgc
    12001 ggggtgtgcg gtgaaggtga ttctgctcgg cacggccgcg ggcggcgggg tgcctcagtg
    12061 gaactgcgcg tgcgcgaact gcgaggccgt acgcgacggg agtgctcccg cgcggacgca
    12121 ggactgcctc gcggtgagcg ccgacggccg ggcctggtac ctgctcaacg cttcgccgga
    12181 cgttcgcaca cagctgacgt cctgcgcggc cctcgcgccg gggccgggcc cgagggagac
    12241 gccgctgcgg ggtgtgttgc tcaccgacgg cgagctcgac cacacgctgg gactgttcca
    12301 gctcaaggag gccgcaggcc tgcgcgtgtg ggctcccggc gcggtggcgg cgaccgtgcc
    12361 ggcgcgggag atcgcggggc gctaccacgg ctgggagtgg ccacggttga gggagaggtt
    12421 cgagctcgac ggcctggtgg tcaccgtgtt cccggtgagc ggcaagcgcc cgaagtacgc
    12481 cggggactcg accctcgacg gtccgtgggt cgtggcgtac cggatcgagg acccggcgac
    12541 cggcggctcg ctcgtgtacg cgccgtgcgt cgcgcagtgg cccgccgggt tcgacgaatt
    12601 ctgcgcgggg gcgagctgcg tgctgctgga cggctccttc ttcgcgccgg acgagatggc
    12661 gggcgcgacg gccgggggcg tcggctccgg cgcccagctc gcgatgggtc acctgccgat
    12721 ggcgggcgag cacggcagcc tcgcgcgcat ccggcgttcg cggggcactc gctggctgta
    12781 cacgcatgtc aacaacacga acccggtgct gaacccggcg tcgccagagc acgccgccct
    12841 tctcgaagca ggtgccgaac tcccgccgga cgccacggaa ctgctcctct aacggccttg
    12901 ggggcaggcg gggtcaggtg agtgcgggtg cggtgggctt gggtttgacg ggccgcggtg
    12961 ggcggatggt gtggcggagg agccagacca cggccgccag ggccagcgca cacgccgccg
    13021 cggccaggaa cgcggcgggc gggccgctgt gctccaccag gtagccgctc acggactggc
    13081 cgaaggcgag acccagcgtc accgccgtga gcacccagcc gaacgcctcg gccgcggtgc
    13141 ccttcggcgc gacgatctcg atcgccgtcg agtgcgccgt cgactgcggc gtgatgaggg
    13201 caccggcgcc gagcatcgcg atcgccagtg cccacagcgt cgtcggcagc gcgagcagcg
    13261 ccaccagcgc gccgaacagg gcgagcagca cgggcaggcg gagccgcatc ggccggggcc
    13321 acgggcgcag gctgtaggcg acgccgaaac cgaccgagct caccgaccac gccgagagca
    13381 gcagcccgcc gagcgcgagg tggcccgcct cctcggccgc cgcgggcacc gcgacctcga
    13441 cgaacccgat caccatgccg aagcccagcg ccgcgagcgc gagtgtgcgc atgccggggc
    13501 tcgcgagcgc gccgagcagc cgccccccgg tgcgctcctc ggcgggcccc cacgcccgga
    13561 ccgccgggct cagcgcgaac agcaccgcac cggtgaccat gcacgcggcg cccagcacca
    13621 tgccggtgcc aggccatggc gcggcgatca gcagtccggc caggccgggg ccgagaatga
    13681 agaacgtctc catgctgatg gcctcgtagg agaacgccgc gtcccgcgtg ggaccctcgg
    13741 gcacgagccg cgcccacagc gcccgtgacg ccgagccggt catcggctcg gtcacgccga
    13801 tgccaacggc gagcgtcacc agcaacggcg tgggggcatg cgcctcgatc gcgagcacga
    13861 gaatggtcat cgcgaccgag aacagcgccg ccaccagtag caacggccgc gtggggccga
    13921 accggtcgat gatccggccc tggaccaccg agcccgccga gacgccgacg agcgccccgg
    13981 ccgacacgag ccccgccgcg gcgaaggacc cggtctcccg ctgcacgaac agcagcgcgg
    14041 agataccgat catggcgatg ggcagccgtg cgaacaggga ggccaccatg ggcctgcggg
    14101 cgcccggcgt gctcagcgcg atgcggtagt cggccagcgt cgtgcggccg tgggactcgg
    14161 actgggacac gcgtaccagt atgcctcgca gtggtacgcg agtaccactt gtataccgga
    14221 aaagcgacac gccgactcga agaggtgtga gatccgtccc ggatgggtac ttctgtctca
    14281 gttgggtaac agagtgcgga ttccgggcat caaaccatca cattgggcgt ccttgagagt
    14341 gaacggcctt gagttggtgg gtaggggtcg tggatcgtgg aagttacgaa tagcgccgca
    14401 gtctccctcc gggaatcggg tcggggccta caaccggagg gcggggagcg cggactgtcg
    14461 ggggatggtc cgcgcacagc aaggggccgg tgcgccacgt cgggggtggc gcccggcccc
    14521 ttgttatgtc tggagctgcg tgctcagcga gcccggcggg cgagccgctc ggggtcgagg
    14581 atcagcacgc tcttgccttc gagtcgcagc cagccacggt gcgcgaagtc ggcgagcgcc
    14641 ttgttgacgg tctcgcgcga cgcgccgacg tactgggcga tctcctcctg cgtcaggtcg
    14701 tgagtgaccc gcagcaggcc ggcctcctgg ctgccgaagc gctgtgcgag ctgcaacagc
    14761 gccctggcga cgcggccggg aacgtcggtg aagatcagtt ccgcgaccat gttgttcgtg
    14821 cggcgcagcc tgcgcgcgac cacgcgcagt aactgctcgg cgatctccgg acgcgtcgaa
    14881 atccactgcc gcagggcagg ccggtccatc gtcacggcgc tgacctcggt cacggtcgtc
    14941 gcggtcgagg tgcgggggcc ggggtcgaag atcgacagct caccgaacat gtcggaaggg
    15001 cccatgatct ggaacaggtt ctcgcggccg tccgcggact tgcgcccgat cttcaccttg
    15061 cccgacttga tgatgtacag cttgtcgccc ggctcgccct cgttgaagat cacgtggccg
    15121 cggggaaact ccacagtctc caaggtctgc gcaagcgcct cggctgctgc cggttccaca
    15181 ccctgaaaaa tgcccgcgcg ggccagggtc tcgtccacct cgtgcctcct ttgagaagcg
    15241 accgcgatcc tcgaactcaa ggagcgtgtc gccgatcact acgtgcagtg tagggcgtgc
    15301 tcccgagatc gcctcccggc tcgccgtgcc gaggtgaacc cgccctgcgc gggtgatacc
    15361 tcagcgcatt cgcgccaata ccgcctgtca gagcggtgtg gaatcgatct cgtccgatcg
    15421 gccagtgtaa ccgtgacgcg cggcgtctcc gcttgggcgg tggtgggaga acgcgcggga
    15481 ccggctcact gtcaaccgcg gacgcggcgc ggcttcagtt tggcggtctt cccgccgagc
    15541 ctgcgcagcc ggaaaagctc gagcgcacgg ccgattccgt gcccgtacaa ggccctgacc
    15601 tcgtcgggct gggcctgctc gaggaactcc tcgacgtcct caccgcggac ggacacgtgc
    15661 cggagcctgt tctcgacgcg ctccatgccg agcgcgaaca gcatgaccac gaggggcacc
    15721 gcgatgacga accatacggt catgagtctc ctcatcctcg ctcgtggctg gccacggggc
    15781 cgaccttagc caagcacgta tccgtctgct cggacggcgc acgtaggcta gcggtgtgtc
    15841 gtcagccgtc ggtcgcgccc cccggaagcg gcgctcgttc gctgaagaga gccgattgtc
    15901 gttggtaaga cgcgcccggc gtatgaaacg ttgcctcgac gaggcatatc caaacgccca
    15961 ctgcgagctg gatttcacga cgccgctgga acttctcgtc gcggtgatcc tttccgcaca
    16021 gtgcaccgac cagcgcgtca acctgaccac gcccgcgctg ttcgcccgct accgcaccgc
    16081 cgccgactac gcgggagccg accgcacgga gctggaggag ctgatccggc cgaccgggtt
    16141 ctaccgcaac aaggcgacgt cgttgctggg gctcggcgcc gcgctcgtcg agcggcacgg
    16201 cggtgacgtg cctggcaagc tcgaccagct cgtgaagctg cccggcgtcg ggcgcaagac
    16261 cgcgaacgtc gtgctgggcg aggcgttcgg cgttcccggg atcactgtgg acacccactt
    16321 cggcaggctc gtgcgccgct ggggctggac cggcgacgag gatcccgtcc gcgtcgagca
    16381 cgagatcggc gagctgatcc cgcgcaagga gtggacgatg ctctcccacc gcgtgatctt
    16441 ccacggcagg cgggtgtgcc acgctcgcaa gcccgcctgc ggcgcctgcc cgctcgcgaa
    16501 cgactgccct tcctacggag cgggtccgac cgagttcgac gtcgcggcga agctcgtgaa
    16561 gggtcccgag cgcgaccatc tgctttcact ggtgacgaag tcttgaccac tgcgaccaaa
    16621 tgggcgctgg ccgtgggcgt gctcgccctc gccgtgctgg tggccgtgct gccgaacatc
    16681 ggtgacgagc cggcgccgcc gcgggcgggt gaggacctcg gacccgcccg ctcggccgcc
    16741 gcgctggagc cgtgcccgaa gggcagcggc accgtccagc ggctcgccgg cgtggaggcc
    16801 tcgtgcctcg gcgacggctc gcaggtcgac ctcggcagtg cgctggccgg cgagacgacg
    16861 ctggtgaacg tgtgggccac ctggtgccag ccgtgccgcg aggagttgcc gctgctccag
    16921 tcctacgccg cggagccggg cgccgcgcgc gtgctcgccg tgcaggtgca gagcgacgcg
    16981 aaggacggcc tggaactgct ggccgagctc ggcgtgcacc tgccgtccgt gcacgacggc
    17041 gaaggcccga ccgggccggt gcgggaggcg ctgagggtgc cgagggcgct gcccgcgtcg
    17101 tacctggtca ccgaggacgg gcaggtccgc ttcgtcgacg atccgcgcct gttcacctcc
    17161 gtggcgcaga tccgcgagac cgtggaggcg gccaggtgac cggtccgctc gtcgaccctg
    17221 gcgacgtccc ggagtggctg cgcggcctcg tcgaggtcag cggcgagctg gacgcgaaga
    17281 cgttcacgcg cttcgccgcg ccgtccggca ccaggacgag gtccgcggcc gtgctgatcc
    17341 tcttcggcga cgggggcgaa cggggccccg acgtgctgct gctgcgcagg gccgacacgc
    17401 tcggctcgca cgcgggccaa gtggcgttcc ccggcggagg cgccgaggac ggagacgacg
    17461 ggccggtcgg cacggccctg cgcgaggccg aggaggagac cggggtcgtc ccgtcgggcg
    17521 tgcgcccgct cgccgtactg ccggagctgt acgtccccgt gtccggtttc gccgtcacgc
    17581 ccgtgctcgc ccactggcgc gagccgtgcc cggtgcacgc cgtcgacccg gccgagacgg
    17641 ccgccgtcgc gcgggtgccg gtggcggagc tcaccgaccc cgccaaccgc tttctggtac
    17701 gcaggtccgg tgccgactgg aagggcccgg ccttcgaggt cggcgagatg ttcgtgtggg
    17761 gcttcaccgc gggcctgctc tccgtgctgc tcaccctcgg cggctgggag cgggagtggg
    17821 accacacgga cgtacgagac cttgacgtag cgttggcgcg acacgaggcc cgcgtcaggc
    17881 gcgcggaggc cggctcgcgc gagtagggag agacgttgaa ctgggtcgac gtgctggtga
    17941 ttctgctggc attgctggcg gcggtctccg gcgctcgcca gggggtcgtg atcgcgctgc
    18001 ccgccttcct cggggtgatc gcgggcgcgg tggtcgggat ccagctggcg ccgatggtcg
    18061 tcgacttctt cgaccatccc gccgcgcgcg tcgcgttcgc ggtgggcacc gtggtctttc
    18121 tcgtcgcgct gggcgagacg ctcggcgtgt ggctcggcaa caagctcaag agcaggatcc
    18181 gctcgccgaa gctgtccggc gtggacagtt cgctcggcgc ggtcgtccag ggcgtcgtcg
    18241 tgttcgtggt ggcgtggctc atcgcgttgc cgctcaccag cgtcgccgcg ttgccggggc
    18301 tggccagggc gatcaacaac tcggttgtgc tcggcggagt caactcgatg atgcccgacg
    18361 ccgcgcaggg gctgcccggt gagctgcgcc agctcctcga cgcctccggc ttcccgtcca
    18421 ttgtggatcc gttccagaag gcgccggtgc gtgagaccgg cccgcccgac gcggcgttgc
    18481 agaacagcgc cgtcgtgcag gacctgcggc cgagcgtgct gaagatccgc ggcatcgcgc
    18541 cgtcgtgctc gcgttcactg gagggcagcg gcttcgtggt ctcgccggag cgggtgatga
    18601 ccaacgcgca cgtggtggcc ggcaccgagg aggtggcggt cgagaccgac gccggacgcc
    18661 tcgacgccag ggtcgtgtac tacgacccgg agaccgacct cgcgatcctc gctgtgcccg
    18721 ggctcaccgc cgcgccgctg gcgctcgacc cgcagcctgc gcaggagggc gacgacgcga
    18781 tcgcgctggg ctacccgctc gacggcccct acaccgcgtc cgccctgcgc gtgcgccagc
    18841 gcatcaacct gcgcggcccc gacatctacg acgccaacac cgtggagcgt gacgtcttca
    18901 cggtgcgcgg tcaggtccgt agcgggaact ccggcgggcc gatggtggat cccgacggcg
    18961 acgtgatcgg cgtggtcttc ggcgcgtcgg tggaggaccc cgagaccggg ttcgtgctca
    19021 ccgccgacga ggtgcgtgcc gaggtggagg cggctccggg gctgggcgcc caggtcagca
    19081 ccggcccctg cacgtcctga ccggatcctc gccctgcagt gaaggccacc ctcactgcgt
    19141 tcaacgcagt gagggtggcc ttcactgcgg ttgcccgctc ccgcgcagga agctcacgag
    19201 cgccttcgcc gtgttctccg gctcctccag ttgcgggtag tgccccacgc gcggcatcgt
    19261 ctcgaagcgc gagcgggggc cgagccacgg cgcggagtca tgcgcggtgc cggggagcac
    19321 gacggggtcg gcggcgccgt gcagctgcag caccggcatc cgcagccgtg cgtcgacggc
    19381 ctcggcgaac cgcctgccct cgccgcggaa ctgcgcgcgg aaggcccacc ggtagtactc
    19441 gagcgcgctg tgcgcgacgc cgggaacgag catcgcgttg cggaacgccc tcgcggtctc
    19501 ggcgaagccg ggcccgcgcc gccacgtctc gccggaccag tcgtggagca gccgttcgac
    19561 ggcggcggcg tcgtccttca cgagccagcg ttccggccgc atcggcatct ggaaccgcag
    19621 caggtgggac atcgcgcggg cctggctgcg ccgcctgcgc agggcggagc gcccgaacgc
    19681 ggagcgcagc gcgagcgggt gcgccccgcc gagcacgctc accgagctga cgacgcgggg
    19741 atgcagggtc gcggcggtcc aggcgagcag gccgccccag gcgtggccga cgaggtgcgc
    19801 acgccgctcg cccagcgcgc ggaccaggcc cgcgacgtcg ccggcgagcg tccaggcgtc
    19861 gtagccccgc ggtggcttgt ccgagtcgcc gtagccccgc aggtcggccg ccaccacgcg
    19921 gaacccggcc tcggagagcg aacgcagctg gtggtgccac gtccaccaga actccgcgaa
    19981 cccgtgcagc agcagcacca gctcaccgga tccggcctcg gcgacgtgca ggcggatccc
    20041 gttcgcggag acgtcgcggt gggtccaggg acccaccagc cggacggtcg acgggtcggg
    20101 cgcgggcacg gcgacctgcg gcaccgccgt cagcgctgcg ccggcaggcc cggctccgcc
    20161 gcggcgggct cgggctcgcg ccggggcttc agcgctgcgg ccgtctcctt caggctgtcg
    20221 atcgagcgtt gcggcgccct gaccttcttc cacttgcggt agccgagcag gccgaacagc
    20281 gcggcggtga ccagcatcag caggaacacg atgccgaacg ccgcccagcg ctgcagccac
    20341 tccgacagca gctcgccgag gaagaaaaag aagaagaacg agctgtacag cgcgacgacg
    20401 ccggcgatca cgaagaagac gctgcccttg gccgccttct tggcctcccc gacggtctcc
    20461 gccttgacca gctcgacctc ggccctgaac agggtcgaga ggtgcgccgt cgcgtccttg
    20521 acgagcgcac cgatcgactg gccgtcggcc gcggattcgt tctcttcgga cagcgggatg
    20581 tagggcactg agcccacacg atcgccgccg accggttcgt gtttggggct gctcacgggc
    20641 ctcatcgtgc catgtgatca atccgagggc tcggtgggcg cgccactcgc gtgcaccttg
    20701 ctccgcctga tgagcagcag ggcggcggtg agggacgcga cggccgacgc gatgagcacg
    20761 gccgccttgg ccagctcggc cgcctcgccc tccagggaga gctccgcgat cagcaggctc
    20821 acggtgaagc cgaccgcgcc gagcatcgag agtgccccga tatcgagcca ggtcagcgag
    20881 ccgggcagcc gcgcgatgcc gagccggacg gccagtgcgg agaaaccgag gatgccgacg
    20941 agcttgccgc cgagcaggcc cgccatcacc gcgagcggga tggggctcgt gaacaccgcg
    21001 ctcagcgcgt cggcgctgac cgcgatgccc gcggcgaaca gcgcgaacat cggcacggcg
    21061 aagccggccg accacggctg cagccggtgt tcgagccgca gggcgggagc ctcgtgctcg
    21121 ccccggtcgg cccgcacccg cgtgagcagt ccgagcgcga cacccgcgat cgtcgcgtgg
    21181 acgccggccg cgtgcaccga ggcccagacg acgagggcca gcggcacgta gatccaccac
    21241 gcccggacgc ggcggtgctg caggtaggcg tagcaggcca gccccgagac ggcgatcgcc
    21301 gcggcgacga ggctgaagct ctcggtgaag agcgcggcga tcacgatgat cgcgccgagg
    21361 tcgtcgacca cggcgagcga gagcaggaag acgcgggcgg ccgtgggcag gttcgagccg
    21421 gtcagcgcga gcaccccgag tgcgaacgcg atgtcggtcg ccaccgggat cgcccacgcc
    21481 tgctcgatgc ccggctcgcc ccacgcgatg ccgacggcga tcagcgcggg cgcgatcatg
    21541 ccgcccgccg cggcgatgat cggcagagcc gcggacttga ggttggacaa ctcgccgacc
    21601 acgagttctc gtttgagctc cagcccggcg acgaagaaga acaccgccag caggccgtcc
    21661 ttcgcccagt ccccgatgga gaggttcagg tgcagcgact cgggtccgat gcggaagtcg
    21721 cggacggtcc ggtagacgtc gtcgagcggc gagttcgccc agagcagcgc gatggccgtg
    21781 gcggcgagca gtagcatgcc gccggtcgtc tcgacccgca ggaaacgggc gaactcggat
    21841 acggcctgcg cagggcggcg agaagtgttc acgggcggct ccagggatcg gcgatgagac
    21901 cgccgaccag acttcccggc acacctgcct accaccctaa ctggtcgccc ggcgtggcct
    21961 gacccccgtc ggtccggaat ttactcagca gtaacctatc gtgttggtgg tttt
//
