LOCUS       NZ_SWMS01000006        25960 bp    DNA     linear   CON 10-DEC-2024
DEFINITION  Prauserella endophytica strain CGMCC 4.7182 Scaffold6, whole genome
            shotgun sequence.
ACCESSION   NZ_SWMS01000006
VERSION     NZ_SWMS01000006.1
KEYWORDS    WGS; RefSeq.
SOURCE      Prauserella endophytica
  ORGANISM  Prauserella endophytica
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Prauserella; Prauserella
            coralliicola group.
REFERENCE   1  (bases 1 to 320027)
  AUTHORS   Liu,J.M., Habden,X., Guo,L., Tuo,L., Jiang,Z.K., Liu,S.W., Liu,X.F.,
            Chen,L., Li,R.F., Zhang,Y.Q. and Sun,C.H.
  TITLE     Prauserella endophytica sp. nov., an endophytic actinobacterium
            isolated from Tamarix taklamakanensis
  JOURNAL   Antonie Van Leeuwenhoek 107 (6), 1401-1409 (2015)
   PUBMED   25832628
REFERENCE   2  (bases 1 to 320027)
  AUTHORS   Li,Q.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-APR-2019) Yunnan Institute of Microbiology, Yunnan
            University, No. 2 Cuihu North Rd, Kunming, Yunnan 650091, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 10.16x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_005146945.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 16:32:08
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,852
            CDSs (total)                      :: 7,795
            Genes (coding)                    :: 7,703
            CDSs (with protein)               :: 7,703
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 34 of 92
            Pseudo Genes (incomplete)         :: 69 of 92
            Pseudo Genes (internal stop)      :: 2 of 92
            Pseudo Genes (multiple problems)  :: 13 of 92
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 18:09:25
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 117909
            Orig. end                         :: 143869
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            SWMS01000006.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..25960
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..25960
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25960
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:15960](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..15960
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            505..1689
                     /locus_tag="FCN18_RS13440"
                     /old_locus_tag="FCN18_13440"
     CDS             505..1689
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017985592.1"
                     /locus_tag="FCN18_RS13440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_13440"
                     /product="beta-1,3-glucanase family protein"
                     /protein_id="WP_137095229.1"
                     /transl_table=11
                     /translation="MLGRRSFLAGLGAAALALPTGTAWARGTAQATLPLTIVNESGEFA
                     GSSVWVYIVGTDLVSNVQCRVTPDGRAVPVSLSDNGSDGFTDYAIPLAASGPTRLNLPT
                     MSGRVYVALGRKLRFKAVGDGAGRAALQYPAGWVESDPNFPVLHDFVEFTHVAPGTPNL
                     RPGMYCNTTMVDQFSVPLAIRLDGERSQTTGTLADGGRDRIFADLAAQQDFGSLVVDDL
                     RVIAPGHGLDSGRFRADYFATYIDEVWNRYSGTDLRIETEGGGFTGRVDGAGNFVFTKD
                     TGETTRPFAKPSTRDVLFCDGALAAPNDGVTGPVAAVLGAGFNRSILHTGSTQPGTDPG
                     SFYGHAVTNHYARVLHANTVDGKAYGFAFDDVAGFASYIEDPAPASVTVTLTPF"
     gene            1703..2701
                     /locus_tag="FCN18_RS13445"
                     /old_locus_tag="FCN18_13445"
     CDS             1703..2701
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017985593.1"
                     /locus_tag="FCN18_RS13445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_13445"
                     /product="chitinase"
                     /protein_id="WP_112268800.1"
                     /transl_table=11
                     /translation="MRIPRRFSRLLAAAATGAALLLAGATATAEPTPAGALPGKQLTGY
                     WQNFVNGATPLRVADVSAAYDVIVLAFAEADPARPGAVTFGVDPGLSSALGGYDEAALK
                     ADIAAKKAEGKSVVLSIGGERGDVDLGGPANVTNFVDSFAAIAAEYGIQGLDVDLEHGF
                     DVANMASAIQRLRERMGEGFLLTMAPQTLDVQPGGAYLQLIDQVKDLITVVHTQYYNSG
                     SMNGCHGQVVTQGTVDFITAQACILLQRLRPDQVSLGLPATSSAAGSGYVSPDVVTAAL
                     DCLTTGSRCGSYVPETPFPGLSGVMTWSVNWDAASGGSFSGPVRAHLDSLT"
     gene            complement(2690..3196)
                     /locus_tag="FCN18_RS13450"
                     /old_locus_tag="FCN18_13450"
     CDS             complement(2690..3196)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020667298.1"
                     /locus_tag="FCN18_RS13450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_13450"
                     /product="2'-5' RNA ligase family protein"
                     /protein_id="WP_137095231.1"
                     /transl_table=11
                     /translation="MVRLAFAVRPPEAVRAVVAALPRPELARTTWSLPEQWIVKLRPLG
                     HVPSSLREPLLGAAAAALDGAPAPLARLGPATHRLAGQWLSVPVNGLDELAADIFAATE
                     PLVPVTHPQPFRGELVLARGRPPRELSGTAIEAAWRVTEVLLVADHSSPRGPRLEDVGA
                     IPLGE"
     misc_feature    complement(3259..3272)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.16"
                     /tool="antismash"
     misc_feature    3260..3271
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.83"
                     /tool="antismash"
     misc_feature    complement(3274..3285)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.99"
                     /tool="antismash"
     gene            3316..5367
                     /locus_tag="FCN18_RS13455"
                     /old_locus_tag="FCN18_13455"
     CDS             3316..5367
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020672935.1"
                     /locus_tag="FCN18_RS13455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_13455"
                     /product="sorbosone dehydrogenase family protein"
                     /protein_id="WP_137095233.1"
                     /transl_table=11
                     /translation="MSKPRWSLLATVALVGTLLSGTQAAAQADAPIMDPIPEDPVTSGL
                     GLTVEEVAQFPKSEPTPAPTDPRLMRHARINYLGELPDGSGRQYVPDLNGNLYFLSDDD
                     DPYVYLDVKARFPDFFSGRGMGQGFGFVAFDPRFQRNGKFYTVHTEAGAALEKPTTYPA
                     QPGTRYHGIVTEWIADDPEADVFSGTHREVLRFGFAQQIHGIQQIDFNPTASRHDEDYG
                     LLYVAVGDGGLGVSSTEPQDLSTPHGKILRIDPDGTGSGNGQYGVPRANPFVGQEGALG
                     EIWAYGMRDPHRFSWDPRSPHRMYLGHIGQHAIEAVYEVREGDNLGWSEREGTFRYERG
                     DGCWLYPLPEDDDKYGYVYPVAQYDHNPPPDWDCGDVGRAISGGFVYRGDIPELRGKYL
                     FADLVDGRVFYTEQNQMKRGHDPATVHTLMIYDEHGNRVSTPELAGDARVDLRFGRDAE
                     GELYLLAKANGKIWKVTGARKFSSCGTAGAGVGDAMDAGSWAPVTPEKWRFPGREVVLA
                     EAGEARPGPRRPFEYAVLTKGGEYGSVRVDAEVRLDTPVTEANRDVIIVFGYRSDTEFY
                     YAHLSSDNSIYPHNGIFKVNNADRERIDDQWNATVSRGAAPAITDASWHDVRVTHCAAT
                     GEIAVYVDGARNPLMTAVDTTFASGRVGFGSFDNIGRLRNLEVSGTRA"
     misc_feature    3337..3339
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(5468..6217)
                     /locus_tag="FCN18_RS13460"
                     /old_locus_tag="FCN18_13460"
     CDS             complement(5468..6217)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020659919.1"
                     /locus_tag="FCN18_RS13460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_13460"
                     /product="sigma 54 modulation/S30EA ribosomal C-terminal
                     domain-containing protein"
                     /protein_id="WP_137095235.1"
                     /transl_table=11
                     /translation="MGRQRWTGGVVVQTRGEVLDSARDYVRKQIAGLARKLPDRLVSAR
                     VKLVAFAKPSAPVPALAQANLDVAGRAVRAQVAAAFFAEAGGLLRARLREQVASLTGPR
                     TFRPWRGAAPEVPAARSRGPREIVRCKEFPLCRCDPAEAAFTMDLRDYDFHLFVDADTG
                     EDSVVYRAGPTGYRLARLHSPVPPRDRPAVPLTVRPRPVPVESAAGAAAGLDRTELPFA
                     FFRDHETGRGSVVYRRYDGHYGLITPA"
     gene            complement(6292..6966)
                     /locus_tag="FCN18_RS13465"
                     /old_locus_tag="FCN18_13465"
     CDS             complement(6292..6966)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020422869.1"
                     /locus_tag="FCN18_RS13465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_13465"
                     /product="phosphoribosyltransferase"
                     /protein_id="WP_137095237.1"
                     /transl_table=11
                     /translation="MEFENRREAGRELAGRLGYLRGRHPIVLGLPRGGVVVARQIADAL
                     GAPLDVLLVRKIGAPGRPELAIGAVGEGGVLVTNADILRRLRLTAEEVDEAARRELAEL
                     DRRALVLRRGRAPLPVTGRTVVLTDDGIATGASVKAALRVLRARGASRIVLAVPVAPAD
                     VLEELSHSTDHTVCPNRRVWMRAVGNWYRDFSEVSDADVVALLPDPADDVPEQVTGRSR
                     DR"
     gene            7115..8176
                     /locus_tag="FCN18_RS13470"
                     /old_locus_tag="FCN18_13470"
     CDS             7115..8176
                     /NRPS_PKS="Domain: PKS_ER (15-268). E-value: 1.1e-08.
                     Score: 26.5. Matches aSDomain:
                     nrpspksdomains_FCN18_RS13470_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019815569.1"
                     /locus_tag="FCN18_RS13470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_13470"
                     /product="NAD(P)-dependent alcohol dehydrogenase"
                     /protein_id="WP_113644702.1"
                     /sec_met_domain="ADH_N (E-value: 2.2e-28, bitscore: 92.7,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 7e-26, bitscore:
                     85.1, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRALRLLAWKSEPEFADVEEPRPGPGQVVVRIAGAGVCHSDLHLM
                     HDFEPGQLPWGPPFTLGHENAGWVHALGEGVTGLAPGQPVAVYGPWGCGVCRNCRVGVE
                     TYCENPEGAPAPGGGGGLGVDGGMAELMLVPHARHVVPVPEGLDPVLAAPLTDAGLTPY
                     HAVRRSWPKLVPGSTAVVIGVGGLGHLALQIVKATTAARVIGVDAREEALTHARELGAD
                     LALPSGDDTAARIRDVTRGVGADVVIDCVGNDATLALGAACARQLGDLTIVGIGGGTLP
                     VSFFTLPYELSVQTTYWGSRPELIEVLDLAARGLLRTTVTRFAFDEAPEAYARLARGEL
                     TGRAVVTPPADGA"
     aSDomain        7160..7918
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FCN18_RS13470_PKS_ER.1"
                     /evalue="1.10E-08"
                     /label="FCN18_RS13470_PKS_ER.1"
                     /locus_tag="FCN18_RS13470"
                     /protein_end="268"
                     /protein_start="15"
                     /score="26.5"
                     /tool="antismash"
                     /translation="ADVEEPRPGPGQVVVRIAGAGVCHSDLHLMHDFEPGQLPWGPPFT
                     LGHENAGWVHALGEGVTGLAPGQPVAVYGPWGCGVCRNCRVGVETYCENPEGAPAPGGG
                     GGLGVDGGMAELMLVPHARHVVPVPEGLDPVLAAPLTDAGLTPYHAVRRSWPKLVPGST
                     AVVIGVGGLGHLALQIVKATTAARVIGVDAREEALTHARELGADLALPSGDDTAARIRD
                     VTRGVGADVVIDCVGNDATLALGAACARQLG"
     misc_feature    complement(8193..8207)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.58"
                     /tool="antismash"
     misc_feature    complement(8245..8254)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     misc_feature    8280..8294
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.35"
                     /tool="antismash"
     gene            8297..8899
                     /locus_tag="FCN18_RS13475"
                     /old_locus_tag="FCN18_13475"
     CDS             8297..8899
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FCN18_RS13475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FCN18_13475"
                     /product="hypothetical protein"
                     /protein_id="WP_137095239.1"
                     /transl_table=11
                     /translation="MSDSTTSTCLGRFLRSLFPGRNPVARTSDRIEAAVLLLAIVVPLL
                     ALPIAAALGSDTYARESRAAELEASTRYESTAVLLTDAVLESPTIYAGGRQTVQVRAEW
                     QRPDGSPGTGLVVAEAGLEKGSEVRVWLDESGERVQPPRTQAMAAWNAAAVAITAWLSV
                     TLVCALSWWALHALLDRARRQRWQREWDELDREIHGL"
     gene            complement(8944..9240)
                     /locus_tag="FCN18_RS13480"
                     /old_locus_tag="FCN18_13480"
     CDS             complement(8944..9240)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017982310.1"
                     /locus_tag="FCN18_RS13480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_13480"
                     /product="dsRBD fold-containing protein"
                     /protein_id="WP_137095241.1"
                     /transl_table=11
                     /translation="MARPAQWTMSVVLEENNGTTRARVRLGDDRGNHFDGIGLAHRGVD
                     VARVPQVAGELAVARALTDLTEELLTAVAADIESAIGVPAFGSPAPSLTPTPK"
     misc_feature    complement(9292..9311)
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: medium, score: 25.32"
                     /tool="antismash"
     misc_feature    9435..9453
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.96"
                     /tool="antismash"
     misc_feature    9565..9580
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.13"
                     /tool="antismash"
     misc_feature    complement(9609..9620)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.32"
                     /tool="antismash"
     gene            10001..10867
                     /gene="hpnC"
                     /locus_tag="FCN18_RS13485"
                     /old_locus_tag="FCN18_13485"
     CDS             10001..10867
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009154298.1"
                     /locus_tag="FCN18_RS13485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_13485"
                     /product="squalene synthase HpnC"
                     /protein_id="WP_112268813.1"
                     /sec_met_domain="phytoene_synt (E-value: 3.3e-43, bitscore:
                     142.1, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.4e-44,
                     bitscore: 146.8, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPAERSTLQEPAALRRVLAKARDENFPVALRLLPAAQRGHLLAL
                     YAFARMVDDLGDEAEGDRLRLLDAVSHDLDRIYAGSPPPEPLYQRLSTTIYACGLPREP
                     FERLVEANRRDQTVRRYATFGDLLGYCALSADPVGRLVLGVFGVATEERLPLSDRVCSA
                     LQVLEHCQDVAEDARAGRIYLPAEDLDRFGVAEGDLLSGRASREVRALVGYTAQRAVAL
                     LDEGEPLVGTLSGTARLAVAGYVAGGRATAVALAGAGFDVLATTPRPSKGRTIAEWVRL
                     LVTGGAR"
     gene            10864..11721
                     /locus_tag="FCN18_RS13490"
                     /old_locus_tag="FCN18_13490"
     CDS             10864..11721
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005465126.1"
                     /locus_tag="FCN18_RS13490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_13490"
                     /product="squalene/phytoene synthase family protein"
                     /protein_id="WP_137095243.1"
                     /sec_met_domain="phytoene_synt (E-value: 2.7e-56, bitscore:
                     185.0, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.6e-66,
                     bitscore: 218.9, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNVADAYEECERITRQQARNFSYGIRLLPPAKRRALSAVYAFARR
                     IDDIGDGDLAGEVRLEALENARKALHSLDEPGGDPVLIGLGDAAERFGLTLGAFDELID
                     GCRADVLGTTYETFDELHHYCRCVAGSIGRLSLAVFGGAHPRRDARLADDLGIALQLTN
                     ILRDVLEDRRNGRIYLPAEDLRRFGCTLDLDEGGWLADSEEALLPLLEYEAARAEEWYG
                     RGLVLLDSLDARSRACCAAMAGIYHRLLRRMALRPGLVLHGRTSLPDWEKLTVAARALA
                     GARP"
     gene            11718..13049
                     /gene="hpnE"
                     /locus_tag="FCN18_RS13495"
                     /old_locus_tag="FCN18_13495"
     CDS             11718..13049
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009154300.1"
                     /locus_tag="FCN18_RS13495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_13495"
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_137095245.1"
                     /sec_met_domain="DAO (E-value: 7.9e-13, bitscore: 42.9,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAHVVVVGGGLAGLTAACDLADDGLRVTLLEARGRLGGATFSFR
                     RDGLSVDNGQHVLLRCCTEYRALLARLGTAEGIAMQERFRMPVLAPGGRLTELTRTWGP
                     APLHLVAGLARYGALPVTDRLRAFRAAAAMRLLDPDDPALDERGFGDWLRGHGQNGATL
                     AALWNLISVAALNCDADEASLALAAKVFRTALLDRADAADIGVPRWPLEDLHVRPAEKY
                     LLARGAEIRTRSAVRAVERRDRGFAVRLDGETLTADAVVVAAPPEPSAKVCPAEAGVSG
                     ARLAGLGAAPIVNVHVVYERPVTDLPFAATTGSPVQWIFDRTDVAGLSAGQYLTISLSA
                     AHTWLDTPVPELREIFLTELGRLLPAARTTPCTRFFVTRERRATFRQAPGTGRLRPQPE
                     TRLPGLVLAGSWTATGWPDTMEGAVRSGHRAAGLVSAHAWGGAR"
     gene            13046..14053
                     /locus_tag="FCN18_RS13500"
                     /old_locus_tag="FCN18_13500"
     CDS             13046..14053
                     /EC_number="2.5.1.-"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005439219.1"
                     /locus_tag="FCN18_RS13500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_13500"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_112268819.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 6.9e-63, bitscore:
                     206.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATLPSEVTATQALVQPALRDAVGELRPPMRRIVSYHLGWTDEH
                     GQARNGGGGKALRPALALLAAQAVRAGPEAALPGAVAVELVHNFSLLHDDVMDGDLERR
                     HRPTVWRLFGTPAAILAGDALLTLAVDVLERAADPTATRCLTASVQDLIAGQSQDVGFE
                     TRMDVGLDECLEMAAGKTAALMRCAAEVGALLGRASPVASGLLAEFGRCLGMAFQLVDD
                     LLGIWGSPDVTGKPVLADLRVRKKSVPVVAALDSGTGPGAALRELYGRPDPPTEEELRT
                     MAELIERSGALAWTRDRAQRYVVEARSCLDRLAPPEPIHAALSDLTRFVVERDR"
     gene            14059..15960
                     /gene="shc"
                     /locus_tag="FCN18_RS13505"
                     /old_locus_tag="FCN18_13505"
     CDS             14059..15960
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0016866 - intramolecular transferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009942896.1"
                     /locus_tag="FCN18_RS13505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_13505"
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_228713945.1"
                     /sec_met_domain="T2TS (E-value: 5.2e-153, bitscore: 504.7,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIERTTAPAAAREAAERAREYLLSLQHEEGWWKGELETNVTMDAE
                     DLMLRRFLGILDEQTLAESARWIRSCQREDGTWANFHGGPADLSTTVEAYVALRMAGDP
                     VGSEHLRKAREYILAHGGIEATRVFTRIWLALFGEWSWDELPVLPPEMVLLPDWFPLNI
                     YDWACWARQTVVPLTVVGAARPCRALGVSVRELRTGRPGPEPASLLTWAGAFQRLDGVL
                     HVLERVPVKPLRGVALARAERWILDRQEADGGWGGIQPPWVYSILALNLRGYGTDHPVL
                     RKALDGLDGFTIRERTAEGMVRRLEACQSPVWDTALAIIALLDAGLPPGDPALVRATDW
                     VLREEIRSDGDWSVRRPDLTPSGWAFEFANDHYPDTDDTAEVVLGLNRVHHPEPARLGE
                     ALDRAVAWTTGMQSRDGGWGAFDADNTRTLPEKLPFCDFGAVIDPPSADVTAHIVEMLA
                     ARGEADAQPARRGVRWLLRHQERDGSWFGRWGANHVYGTGAVVPALVACGIPVTHPAIR
                     RAVGWLTRHQNPDGGWGEDLRSYVDPAWVGKGESTASQTAWALLALLAAGERGDPVVRG
                     VEWLTRTQREDGGWDEPWFTGTGFPGDFYINYHLYRLVFPLMALGRYVEVTSDETTG"
     gene            15944..17464
                     /locus_tag="FCN18_RS13510"
                     /old_locus_tag="FCN18_13510"
     CDS             15944..17464
                     /EC_number="1.17.7.4"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051745 - 4-hydroxy-3-methylbut-2-enyl
                     diphosphate reductase activity [Evidence IEA]"
                     /GO_process="GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009154303.1"
                     /locus_tag="FCN18_RS13510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_13510"
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="WP_113644674.1"
                     /transl_table=11
                     /translation="MKPPDDDLIVVSPLLLEARSVRRGLRGPSGGHVVLAGPHARRAKR
                     VARALRQYPDRPVAVAGVAGALVHGLRPGDLVVASEVRSAQGTHHCRSAPLLAAQLRKL
                     GLTVHVGPMVETDHVVWQPEGARLALDGAIAVDMESARLLDMIGSRPAAVVRAVVDTPT
                     RSLLHPATVPGGIAALRSLRAVGPALRRWAAATGDRTVLLAGPRSFCAGVDRAVEIVER
                     LLDRHAPPIYVRKQIVHNSRVVGELERRGAVFVDELDEVPENATVVFSAHGVSPAVREA
                     AEERGLDVVDATCPLVAKVHGEARRFARDGDTVFLIGHAGHEEVEGTLGEAPERTVLVE
                     RPEDVAGLEVEDPDRVAYLMQTTLAMDEAAGVVDALRDRFPALRGPGSDDICYATTNRQ
                     DAVRVVARESDVVLVAGSGNSSNSRRLVEVAQREGARAYLVDNVNEIDLDWLVGARTVG
                     LSAGASAPTVLVDEIVDALAGLGAVETRERTTATETVNFSLPKEVRHR"
     gene            17461..18471
                     /gene="hpnH"
                     /locus_tag="FCN18_RS13515"
                     /old_locus_tag="FCN18_13515"
     CDS             17461..18471
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019818822.1"
                     /locus_tag="FCN18_RS13515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_13515"
                     /product="adenosyl-hopene transferase HpnH"
                     /protein_id="WP_112268825.1"
                     /sec_met_domain="PF04055 (E-value: 1.2e-19, bitscore: 65.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 3.9e-10, bitscore: 33.8,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNMPLHQAIRVARHVATQKLRKRDKFPFIMELEPILACNLKCGGC
                     GKIQHPANILKQRMPVEQAVAAVEEAGAPMVSIAGGEPLMHPEIDRMVNELVKRKKYVF
                     LCTNAVLLRKKIDKLDLKPSKYFAFTVHLDGLRERHDAAVAKEGVFDEAVAAIRELKRR
                     GFRVTTNTTVFNTDTPQSVIDVLDYLNDELEIDSLMLSPAYAYEKAPDQEHFLGVQETR
                     ELFRKAFANGNRKRWRLVHSPLFLDFLEGKVDFECTAWGVPLYTLFGWQKPCYLMGDGY
                     VKTYRELVETTEWEKYGRGRDPRCANCMAHCGYEPTSVLATMSSLKESIRAARET"
     gene            complement(18737..19477)
                     /locus_tag="FCN18_RS13520"
                     /old_locus_tag="FCN18_13520"
     CDS             complement(18737..19477)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (6-165). E-value: 1.5e-12. Score:
                     39.7. Matches aSDomain:
                     nrpspksdomains_FCN18_RS13520_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005452329.1"
                     /locus_tag="FCN18_RS13520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_13520"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_137095250.1"
                     /transl_table=11
                     /translation="MIGAGTTAVVTGGSSGIGAATASVLARRGCDVLVTGRDPAALETV
                     ARRTGARACAADLAGSGAAARVLASAGDVDLLVCNAGVGWAGRLEDMPEADAETLVRVN
                     LLAQILLVRAVLPGMVERGRGHLVFVSSIAGSMSVAGEAVYSATKAGLDAFAASVRGEV
                     AGRGVGVSVVVPGVVDTPFFARRGTPYTRHSPRPVPPERVAAALVAAVERNRAEVFVPR
                     WLRLPARLRGVAPALTDALQRRFA"
     aSDomain        complement(18983..19459)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FCN18_RS13520_PKS_KR.1"
                     /evalue="1.50E-12"
                     /label="FCN18_RS13520_PKS_KR.1"
                     /locus_tag="FCN18_RS13520"
                     /protein_end="165"
                     /protein_start="6"
                     /score="39.7"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TAVVTGGSSGIGAATASVLARRGCDVLVTGRDPAALETVARRTGA
                     RACAADLAGSGAAARVLASAGDVDLLVCNAGVGWAGRLEDMPEADAETLVRVNLLAQIL
                     LVRAVLPGMVERGRGHLVFVSSIAGSMSVAGEAVYSATKAGLDAFAASVRGEVAG"
     CDS_motif       complement(19001..19102)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FCN18_RS13520_0002"
                     /evalue="7.50E-04"
                     /label="PKSI-KR_m4"
                     /locus_tag="FCN18_RS13520"
                     /protein_end="159"
                     /protein_start="125"
                     /score="12.0"
                     /tool="antismash"
                     /translation="HLVFVSSIAGSMSVAGEAVYSATKAGLDAFAASV"
     CDS_motif       complement(19379..19453)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FCN18_RS13520_0001"
                     /evalue="5.00E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="FCN18_RS13520"
                     /protein_end="33"
                     /protein_start="8"
                     /score="16.0"
                     /tool="antismash"
                     /translation="VVTGGSSGIGAATASVLARRGCDVL"
     gene            complement(19474..20364)
                     /locus_tag="FCN18_RS13525"
                     /old_locus_tag="FCN18_13525"
     CDS             complement(19474..20364)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020660514.1"
                     /locus_tag="FCN18_RS13525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_13525"
                     /product="DMT family transporter"
                     /protein_id="WP_137095252.1"
                     /transl_table=11
                     /translation="MTGQDTVLGIAVPAAILAAAAFGVTGALQHRAARRVEGGGPVRWG
                     LVFTLLRQPLWLASLLANGLGIVFQWLALSTAPLVFVQPLLVTSLVFAVFSSSALRRER
                     PDGLVLLGAGLCVAGLALFFLVARPEAGHGTLELRDVLPLATGLAAMIAVAVGLAVRFA
                     GRVRVLALATATGVLYGVTAGVTKLAADDLRRGVVALLTHWHFYVVVVCGVTGFLLSQN
                     AFRVGVALAPALAVIVSLDPLVSIGVGALWLGEELPGGAGRIAGQVLGLAVAIAGIALL
                     SQRAPQVSTPGRENG"
     gene            complement(20361..22748)
                     /locus_tag="FCN18_RS13530"
                     /old_locus_tag="FCN18_13530"
     CDS             complement(20361..22748)
                     /GO_function="GO:0004144 - diacylglycerol O-acyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0045017 - glycerolipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_tran_28_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF018613.5"
                     /locus_tag="FCN18_RS13530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_13530"
                     /product="wax ester/triacylglycerol synthase
                     domain-containing protein"
                     /protein_id="WP_137095254.1"
                     /sec_met_domain="Glyco_tran_28_C (E-value: 1.7e-09,
                     bitscore: 32.1, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVTTSASPEAEGPARLLIVSATMGEGHNATARALRAAAQRVWPGI
                     EVEWADVLDVMGRGTGPVFRWIYATSVERLPWLYEFFYTSVWHHRWFAKAAKRVIGAWS
                     GRRLASVIDAARPDAIVSTYPMGSTGLEWLRRHRGLSVPTAAWVSDIAPHPSWVHEGVT
                     VNMVMHEVAVEAARRSVPGAPVAVSAPPVPGRFAPGDRGAARERLGLPDAGPLAVVSCG
                     SLAFGDPSGAVRELLGGGPAACVVVVTGRDERLRRRLERGFAGDERVRVLGWVDDMATL
                     MTAADLVVTNAGGATALEALACGRAVVLHDPIPGHGKANARLLEEAGLARVCAGPGELA
                     RTVRELVTRPERLRALEEAARRHTSAHRLDDDLRVFARQPGAARARPLPAPDALFLHAS
                     TPEVPQYVGTALVFEPGPPLTRKDAAGMLAAVPGVGGRLLPATLVRRARWDPGEDADPL
                     SLVDEVVAGDLARSVDAFFSVPLDTTRALGAARLVTGLPGQRRALLVKLHHALGDGMTV
                     LQALLSDTDTSTGLSWAIRPTTSVGGNGFRPAPGKLAGGLWELARAGRAPATPLDVAIT
                     GPDRHHAVVRLPGKEVRQAARALGVAPADLLKAVFAEAVHDVLGAQPGARFRLMAPWSL
                     RGTGSLRAAGNHTGAVSVDLPVGPMDLRTRASLVANGLRERIDAGVPEAAHAVVRLIGR
                     LPPRLHALAARSVYRGDWFNAIGTVMPGPRREIRWHGSVMSEAYPVLALAPGSGLAWGA
                     MTWGRWITMVFTGTPAQAAFVDGIAARTDALLAELAGDHAGP"
     gene            complement(22831..24420)
                     /locus_tag="FCN18_RS13535"
                     /old_locus_tag="FCN18_13535"
     CDS             complement(22831..24420)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009154309.1"
                     /locus_tag="FCN18_RS13535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_13535"
                     /product="hypothetical protein"
                     /protein_id="WP_113644678.1"
                     /transl_table=11
                     /translation="MPLTAAHWIYLAGVIVILGTMMARKNIVVPAVAATFLTALVFSGS
                     LITGITAVFDASLVAATNLFNIFLIIALVTAMLHSLQVLGADRKMVAPFRRVMRNGHLA
                     FWALLVVTYFISLFFWPTPAVPLIGAVLVPVAIRAGLRPMAVGMVMACAGQGMALSSDY
                     VIRVAPGLSAQAGGMDPNAVADKAMVLSLVVGGVALLVGYALEFRKMRKPSARLLTEWE
                     ASGRQFATPEPRQAAETAEAAPRQRELVPTGAGARVASDGDGTEPPPAAPLLGGSPDTV
                     DGGDPASADPAREYPRASTFFAVFVPLAYLSLIGYMIVAKISPSVPDLESGQAAGLVGG
                     VAALIVFMAALVGDGRGFLETSATHVVNGLVFAFKAMGIVLPIAGFFFIGNAEFASQIL
                     GTEIRGQGILFDLVAAVQDHIPENGFIAAFAILLVGVVAGLDGSGFSGLPLTGALAGSL
                     GAGAGIDDTTLAALGQMGNIWSGGGTLVAWSSLIAVAGFARVPVLDLARRCFLPVMAGL
                     LAATVFSVVFLG"
     misc_feature    complement(24681..24697)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.28"
                     /tool="antismash"
     misc_feature    complement(25127..25141)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     misc_feature    25470..25483
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.46"
                     /tool="antismash"
     misc_feature    complement(25471..25485)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.38"
                     /tool="antismash"
ORIGIN
        1 gccctccaac gctgtgctct tcgtcggcgg gctgtcggtg gccgcgcctc tgttcggcga
       61 gcagatgctg gtgtggctgg tcgacgcggg cagcctcagc atcatcgcgg cctacctgat
      121 ggtggcgctg agcttcctcg tcctgcgcag gcgtgagccg gacatggcgc gcccgttccg
      181 cgtgccggcc ggccgcacgg tcggtgtgct cgccatcgtg ctgagcctcg gcacgggcgt
      241 gctgttcctg cccggcatgc ccgcgcagct catctggcca tgggagtggg tcatcgtcgg
      301 gctgtggtgg ctggccgggg tcgtgctcgt gctgcgcctg ccgcggatcg ggccgggggc
      361 cgacgccgag gaccggctga tcgatgcggt ccgtgtgggg gacaatcgct gacaagacgc
      421 gacaactttt cgcctttctc ttgcggcggg tcccctatgc ccgcatattg gttcgaacca
      481 cttcgctacg aagggttcat accaatgctg ggtcgcagaa gtttcctcgc cgggcttggg
      541 gccgcggcgc tcgccctgcc cacgggaacg gcgtgggcgc gcgggaccgc gcaggccacc
      601 ctcccgctga cgatcgtcaa cgagtccggt gagttcgccg ggagctcggt ctgggtctac
      661 atcgtcggca ctgacctggt ctcgaacgtc caatgcagag tgacaccgga cggcagagcg
      721 gtgccggtgt cgttgtcgga caacgggtcc gacgggttca ccgactacgc catcccgctc
      781 gccgcgagcg gccccacccg gctgaacctg cccaccatgt ccggtcgcgt gtacgtcgcg
      841 ctcggccgga aactcaggtt caaggccgtc ggggacggcg cgggccgggc cgccctgcag
      901 taccccgccg gctgggtgga atccgacccg aacttcccgg tgctgcacga cttcgtcgag
      961 ttcacccacg tcgcaccggg cacgccgaac ctgcggccag gcatgtactg caacaccacg
     1021 atggtcgacc agttcagcgt gccgctcgcc atccggctcg acggcgagcg ctcgcagacc
     1081 acgggcacgc tcgccgacgg cggacgggac cggatcttcg ccgacctcgc cgcccagcag
     1141 gacttcggct cgctcgtggt cgacgacctc cgcgtgatcg cacctggcca cgggctcgac
     1201 tccgggcggt tccgcgccga ctacttcgcc acctacatcg acgaggtgtg gaaccgctac
     1261 tcgggcaccg acctgcggat cgagaccgag ggcggcggct tcaccggccg cgtcgacggc
     1321 gcggggaact tcgtgttcac caaggacacc ggcgagacca cgcggccctt cgcgaaaccg
     1381 tcgacgcggg acgtgctgtt ctgcgacggc gcgctggcgg cgcccaacga cggcgtgacc
     1441 gggccggtcg cggccgtgct cggcgccggg ttcaaccgct cgatcctgca cacggggtcc
     1501 acgcagcccg gcaccgaccc cggctcgttc tacgggcacg cggtgaccaa ccactacgcc
     1561 cgtgtcctgc acgccaacac ggtggacggc aaggcctacg gcttcgcgtt cgacgacgtc
     1621 gccgggttcg cctcctacat cgaggatccc gcgccggcct cggtcaccgt caccctcacc
     1681 ccgttctagg aaaggacctc cgatgaggat cccgcgccga ttctcccggc tgctcgccgc
     1741 cgcggccacg ggtgccgcgc tgctgctcgc cggggccacc gccacggcgg agccgacgcc
     1801 cgccggggcg ctgcccggca agcagctgac cggttactgg cagaacttcg tcaacggcgc
     1861 caccccgctg cgggtcgccg acgtctccgc cgcctacgac gtgatcgtgc tggcgttcgc
     1921 cgaggccgac ccggcgcgcc cgggcgcggt caccttcggc gtcgacccgg gcctgtcgag
     1981 cgcgctcggc ggctacgacg aggccgcgct caaggccgac atcgccgcca agaaggcgga
     2041 gggcaaatcc gtggtgctct cgatcggcgg cgagcgcggc gacgtcgacc tgggcggccc
     2101 cgcgaacgtg accaacttcg tcgactcgtt cgccgccatc gccgccgagt acggcatcca
     2161 gggcctcgac gtggacctgg agcacggctt cgacgtcgcc aacatggcga gcgcgatcca
     2221 gcggctgcgc gagcggatgg gcgagggctt cctgctcacg atggcgccgc agaccctcga
     2281 cgtgcagccg ggcggggcct acctccagct catcgaccag gtcaaggacc tgatcacggt
     2341 ggtgcacacg cagtactaca actccgggtc gatgaacggc tgccacggcc aggtcgtcac
     2401 acagggcacg gtcgacttca tcaccgcgca ggcgtgcatc ctgctccagc gcctgcgccc
     2461 cgatcaggtc tcgctcggcc tgccggcgac gtcgtcggcc gcgggcagcg ggtacgtgag
     2521 ccccgacgtg gtgaccgccg ccctcgactg cctcaccacg ggcagccgct gcgggtccta
     2581 cgtgccggag actccgtttc ccgggctcag cggcgtgatg acgtggtcgg tcaactggga
     2641 cgcggcgagc ggcggctcgt tctccggccc ggtgcgcgcc cacctggact cactcaccta
     2701 gcggtatcgc gcccacgtcc tcgaggcgcg gtcccctcgg cgaggagtgg tcggcgacca
     2761 gcagcacctc ggtcacccgc cacgccgcct cgatggccgt cccggacagc tcccggggcg
     2821 gccgtccgcg cgcgagcacc agctcgcccc ggaacggctg cggatgcgtc accggaacca
     2881 gcggctccgt cgccgcgaag atgtcggccg ccagctcgtc gagcccgttg acgggcaccg
     2941 acagccactg gcccgcgagc cggtgggtgg cgggcccgag cctcgcgagc ggtgccggcg
     3001 caccgtcgag cgccgctgcc gcggcgccga gcagcggctc gcgcagggac gacggcacgt
     3061 ggccaagcgg ccgcagcttc acgatccact gctccggtag tgaccaagtg gtccgcgcca
     3121 gctcgggccg gggaagggcg gcgacgaccg cgcgcaccgc ctccggtggg cgcacggcga
     3181 acgcgagccg gaccatgcgc cttattgtga ccgaacccgg tcactgcttg cttacccgcg
     3241 cccacgggct gtagagtctg caagcgcttt caggaaagcg ctttcaaggc ggacccggac
     3301 tcgaggatga gtgtgatgtc aaagccgaga tggtctttac tggcaacggt cgccctggtg
     3361 ggcacgttgc tgtcgggcac gcaggcggcc gcgcaggccg acgcgcccat catggatccg
     3421 atccccgagg acccagtgac ctccgggctc gggctcacgg tcgaggaggt cgcccagttc
     3481 ccgaagtccg agccgacacc ggctccgacc gacccgcgcc tgatgcggca cgcgcgtatc
     3541 aactacctcg gtgagctgcc ggacggctcg ggcaggcagt acgtgcccga cctcaacgga
     3601 aacctgtact tcctctccga cgacgacgat ccgtacgtct acctcgacgt caaggccagg
     3661 ttcccggact tcttctccgg cagggggatg gggcagggct tcgggttcgt cgcgttcgac
     3721 ccgcggttcc agcgcaacgg gaagttctac accgtccaca ccgaagccgg tgcggcgctg
     3781 gagaagccga cgacgtaccc ggcgcagcct ggcacgcggt accacggcat cgtcaccgag
     3841 tggatcgccg acgacccgga ggccgacgtc ttcagcggca cccaccggga ggttctgcgg
     3901 ttcgggttcg cccagcagat ccacggcatc cagcagatcg acttcaaccc gacggcctcg
     3961 cgccacgacg aggactacgg cctgctctac gtcgccgtcg gcgacggcgg gctcggcgtg
     4021 tccagtaccg agccgcagga cctgagcacg ccacacggga agatcctgcg catcgacccg
     4081 gacggcaccg gcagcggcaa cggccagtac ggcgtgccca gggcgaaccc gttcgtcggc
     4141 caggagggcg cgctcggcga gatctgggcc tacggcatgc gcgatccgca ccggttcagc
     4201 tgggacccga ggagcccgca ccggatgtac ctgggccaca tcggccagca cgcgatcgag
     4261 gcggtctacg aggtgcgcga gggcgacaac ctcggctgga gcgagcgcga gggaacgttc
     4321 cgctacgagc ggggcgacgg ctgctggctg tacccgctgc ccgaggacga cgacaagtac
     4381 ggctacgtct accccgtggc gcagtacgac cacaacccgc cgcccgactg ggactgcggt
     4441 gacgtcggcc gcgcgatcag cggcggattc gtgtaccggg gcgacatccc ggagctgcgc
     4501 ggcaagtacc tcttcgccga cctggtggac ggcagggtgt tctacaccga gcagaaccag
     4561 atgaagcggg gccacgaccc ggccaccgtc cacacgctga tgatctacga cgagcacggc
     4621 aaccgcgtca gcacgcccga gctcgccggt gacgcccgcg tggacctccg cttcggccgc
     4681 gacgccgaag gcgagctgta tctgctggcg aaggcgaacg gcaagatctg gaaggtcacc
     4741 ggcgcgcgga agttctcgag ctgtggcacg gcgggcgccg gggtcggcga cgcgatggac
     4801 gccggcagct gggctccggt gacaccggag aagtggcggt tccccgggcg tgaggtggtc
     4861 cttgccgagg cgggcgaggc gcggccgggt ccgcgcaggc ccttcgagta cgccgtgctg
     4921 accaagggcg gggagtacgg ttcggtgcgc gtcgacgcgg aggtccggct cgacaccccc
     4981 gtgacggagg ccaaccggga cgtgatcatc gtcttcgggt accgctcgga cacggagttc
     5041 tactacgcgc atctgtcatc ggacaactcg atctacccgc acaacggcat cttcaaggtg
     5101 aacaacgccg accgggagcg catcgacgac cagtggaacg cgacggtctc gcggggcgcg
     5161 gccccggcga tcaccgacgc cagctggcac gacgtgcgcg tgacccactg cgcggccacc
     5221 ggtgagatcg cggtgtacgt cgacggtgca cgcaacccgc tgatgacggc ggtcgacacg
     5281 acgttcgcct cgggccgcgt cggcttcggc tcgttcgaca acatcggcag gctgcgaaac
     5341 ctggaggtga gcggcaccag ggcctgaccg cggccggagc ccttccggcc gcggtgaacc
     5401 gcagtgaagg ccaccttgcc tgcgttcaac gcagggaagg tggccttcac tgcggccggg
     5461 tcgcggttca ggcgggcgtg atcaacccgt agtgcccgtc gtagcgccgg tagaccaccg
     5521 agccccggcc cgtctcgtgg tcgcggaaga aggcgaacgg cagctcggtg cggtcgagcc
     5581 ccgccgccgc cccggccgcg ctctccaccg gcacgggccg cggccggacc gtgagcggca
     5641 cggcaggccg gtctcgcggt ggcacggggg agtgcaggcg ggccagccgg tagcccgtgg
     5701 ggcccgcgcg gtagacgacg ctgtcctcgc cggtgtcggc gtcgacgaac aggtggaagt
     5761 cgtagtcgcg gaggtccatc gtgaacgccg cctcggcggg gtcgcaccgg cagagcggaa
     5821 actccttgca ccgcacgatc tccctcggcc cccgggaccg cgccgcgggt acctccgggg
     5881 cagccccgcg ccacggccgg aaagtcctcg gcccggtgag cgacgccacc tgctcgcgca
     5941 gccgggcccg cagcaggccg ccggcctcgg cgaagaacgc ggccgcgacc tgcgcgcgca
     6001 ccgcccgccc cgcgacgtcg agattcgcct gtgccagcgc gggaacgggc gcgctcggct
     6061 tcgcgaacgc gaccagcttc acgcgcgcgg acacgagccg gtccggcagc ttccgtgcca
     6121 gtccggcgat ctgcttgcgc acgtagtccc gcgcgctgtc cagcacctcg cccctggtct
     6181 gcacgacgac gccacccgtc cagcgctgcc tgcccatccg ggcctcacca ccttccgctc
     6241 acgccccgat catcatcggc gggccgggcc ggggcaaggc gggtgatcgg ttcagcggtc
     6301 tcgcgagcgg ccggtgacct gctccggcac gtcgtcggcg gggtcgggca ggagggcgac
     6361 cacgtcggcg tcggacacct cggagaagtc gcggtaccag ttgccgaccg cgcgcatcca
     6421 gacgcggcgg ttcgggcaga cggtgtggtc ggtgctgtgg gagagctcct cgagcacgtc
     6481 ggcgggagcg acggggacgg cgagcacgat ccggctggcg ccgcgggcgc gcagcacccg
     6541 cagtgccgcc ttcaccgagg cgcccgtggc tatgccgtcg tcggtgagca cgacggtccg
     6601 gccggtcacg ggcaggggag cgcggccacg gcgcagcacg agggcgcgcc ggtcgagctc
     6661 ggcgagctcc cgccgggccg cctcgtccac ctcctcagcg gtgagccgca gcctgcgcag
     6721 gatgtcggcg ttggtgacga gcacgccgcc ctcgcccacg gccccgatgg ccagctcggg
     6781 acggcccggc gcgccgatct tgcgcaccag cagcacgtcc agcggtgccc cgagggcgtc
     6841 ggcgatctgc cgggccacga cgacaccgcc acggggaagc ccgagcacga tcgggtggcg
     6901 tccgcggagg taccccagtc ggcccgcgag ttcgcggccg gcttcccggc ggttctcgaa
     6961 ctccatggtt cttccctcca ggtgggttac cgctgatgct cggccacacg gacgccctgg
     7021 tgaagagtcg aaggtccctc ggtggcgggg caccggaaag tgtccgatgg tggtggcgga
     7081 agggctcgac cccgcgacga agaagggtgt cggaatgcga gcgttgcgtc tcctggcctg
     7141 gaagtccgag cccgagttcg ccgacgtcga ggagccgagg cccggccccg gccaggtcgt
     7201 ggtgcggatc gcgggcgccg gcgtctgcca ttcggacctg cacctgatgc acgacttcga
     7261 gcccggacag ttgccgtggg ggccgccgtt cacgctcggc cacgagaacg cgggctgggt
     7321 gcacgcgctc ggcgagggcg tcaccgggct cgcgccggga cagcccgtcg ccgtgtacgg
     7381 cccgtggggc tgcggggtct gccgcaactg ccgggtcggc gtcgagacct actgcgagaa
     7441 cccggaaggt gcgcccgcgc cgggcggtgg cggcggcctc ggcgtcgacg gcgggatggc
     7501 cgagctcatg ctcgtcccgc acgcccggca cgtcgtgccg gtgccggagg ggctcgaccc
     7561 ggtgctcgcc gcgccgctca ccgacgcggg gctgacgccg taccacgcgg tgcgccggtc
     7621 gtggccgaag ctcgtccccg gctccaccgc cgtggtgatc ggcgtcggcg ggctcgggca
     7681 cctggcgctg cagatcgtca aggccaccac ggcggccagg gtgatcggtg tcgacgcgcg
     7741 cgaggaggct ctgacccacg cgcgagaact cggcgccgac ctcgcgctgc cctccggcga
     7801 cgacacggcg gcgcggatca gggacgtcac gcgcggtgtg ggcgcggacg tggtaatcga
     7861 ctgtgtcggc aacgacgcga cgctggcgct gggcgcggcc tgcgcgcggc agctcggcga
     7921 cctcacgatc gtcgggatcg gcggcggcac cctcccggtg tcgttcttca cgcttcccta
     7981 tgagctctcg gtgcagacga cgtactgggg gagcaggccg gagctcatcg aggtgctcga
     8041 cctcgccgca cgcgggctgc tgcgcaccac ggtcacgcgg ttcgccttcg acgaggcccc
     8101 cgaggcctac gcgcggctgg cgcgcggcga gctgaccggt cgcgcggtgg tgacgccgcc
     8161 ggcggacgga gcgtgaccgg atcgctccac tgtggaacgg ctgggccgcc cagcgcggtt
     8221 gaggtcgaag gactcttcgc gtgcggccgc cttccggtcc atcctggtgg gtgaggacgg
     8281 gaggaggtcg gccacgatga gcgactccac gacttcgacc tgcctggggc ggtttctgcg
     8341 gagcctgttc cccggccgca acccggtcgc ccgcacctcg gaccggatcg aggccgccgt
     8401 gctgctgctc gcgatcgtcg tcccgctgct ggcactgccg atcgccgccg cgctcgggtc
     8461 cgacacctac gccagggagt cgcgggcggc ggagctggag gcgagcaccc ggtacgagtc
     8521 cacggccgta ctgctcaccg acgcggtgct ggagtctccg acgatttacg cgggcggcag
     8581 gcagacggtg caggtgcggg cggagtggca gcggccggac ggctctcccg gaaccggcct
     8641 cgtcgtcgcc gaggccgggc tggagaaggg cagcgaagtc cgcgtctggc tcgacgagag
     8701 cggtgagcgc gtgcagccgc cgcgcacgca ggccatggcg gcctggaacg ccgccgccgt
     8761 cgcgatcacg gcctggctga gcgtcactct cgtgtgcgcg ctctcctggt gggccctgca
     8821 cgcactgctc gaccgtgcca ggcggcagcg ctggcagcgg gaatgggacg agctggaccg
     8881 cgagatccac ggcctgtgag gggcctgcag tgcacaaagg acggtaatac cgtcgccagt
     8941 ggactacttc ggcgtggggg tcaggctcgg tgcgggggag ccgaacgcgg ggaccccgat
     9001 cgccgactcg atgtcggcgg cgaccgcggt gagcagttcc tcggtgaggt cggtcagcgc
     9061 gcgcgccacg gcgagctcgc cggccacctg cggtacccgg gcgacgtcca ctccccggtg
     9121 ggcgagccct atcccgtcga agtggttgcc gcggtcgtct ccgagccgca ctcgcgctcg
     9181 agtcgtgccg ttgttctcct cgaggacgac gctcatcgtc cactgggcag gtcgtgccat
     9241 atctctcctc cgagccgcgg catccacact cgcagtcccg gcggcgcgag cctagggtcg
     9301 ttcgtcccta tccgaggcgt caaggggccg gaattcggtc cccggatcga cgaaagacac
     9361 aatcgcgcac ttcgtctcga acgatgtgga cagttgaatg cgaacgtgcc gatgacgagt
     9421 aaccggtcag tacacagtgg acgaaaacac aggggtctcg cgtcgccgtg tccgggcctt
     9481 cccgctccgg cgacccgtgt ccgggaagct ccacgtattg tacgcctttc cgggccggtc
     9541 gtgtcagctc gcgggaccaa tctcgttaac acttttcacc gagcgaagtt cgccctgtcg
     9601 gcgtcacgga aaactgttgc gctgaccggc cggggaaata agatcatggt cggtggacgc
     9661 ggcagccgga atagtgggcc cgcagggccc tcaacccgcc agatgtcagg cgccgggtgc
     9721 tccgtcccgg tgctccgagg gggccggaat gggagttgcc cgtagtcagg gcgttgaacg
     9781 acaatggtgt cctctccgct ccggcgcccg gtgcactggc cgaatgggac gaggcggttc
     9841 ggatggacgc gctcggcgag tacgacccgg tcggcggcct cggggcgccg gtggcacagc
     9901 cacctggcct gaaccagaag gaccgtgccg ggccggttcg ccgtccgggc gcggcgccac
     9961 cgcagacctc ccgagtccct gcttcgtgtt ggaggcgtga ttgacacccg cggaacggtc
    10021 gacactccag gagcccgccg cgctgcggcg cgtgctcgcc aaagcccggg acgagaactt
    10081 ccccgtggca ctgcggctgc tccccgccgc ccagcgcggg cacctgctcg cgctgtacgc
    10141 cttcgcccgg atggtcgacg acctcggcga cgaggccgag ggtgaccggc tccggctgct
    10201 cgacgcggtg tcgcacgacc tcgaccggat ctacgcgggc tcgccgccgc cagaaccgct
    10261 ctaccagcgg ctcagcacca cgatctacgc atgcggcctg ccgcgtgagc cgttcgagcg
    10321 gctggtcgag gccaaccggc gcgaccagac cgtgcgccgt tacgccacgt tcggcgacct
    10381 gctcgggtac tgcgcgctct cggcggaccc ggtgggacgg ctggtgctcg gggtgttcgg
    10441 cgtggccacc gaggaacgcc tgccgttgtc cgaccgggtc tgctcggcac tgcaggtgct
    10501 ggagcactgc caggacgtcg cggaggacgc gcgggcgggc cggatctacc tgcccgccga
    10561 ggacctcgac cggttcggtg tcgcggaggg cgacctgctg tccggccgcg cgagccggga
    10621 ggtgcgcgcg ctcgtcggct acacggcgca gcgggcggtc gcgctgctcg acgagggcga
    10681 gccgctggtc ggcacgctct ccggcacggc caggctcgcc gtcgcgggct acgtcgcggg
    10741 cggcagggcg accgccgtcg cgctcgccgg cgcgggcttc gacgtcctcg ccacgacccc
    10801 gaggccgtcg aagggccgca cgatcgcgga atgggtccgg ctgctggtca cgggtggtgc
    10861 gcgatgaacg tggccgacgc gtacgaggag tgcgagagaa tcacgcggca gcaggcgcgc
    10921 aacttctcct acggcatccg gctgctgccg cccgccaagc gcagggcgct cagcgccgtc
    10981 tacgccttcg cccgccgcat cgacgacatc ggcgacggtg acctcgcggg cgaggtgagg
    11041 ctggaggcgc tggagaacgc ccgcaaggcg ctgcacagcc tcgacgagcc gggcggggac
    11101 ccggtgctca tcgggctcgg cgacgccgcg gagcggttcg ggctgacact cggagcgttc
    11161 gacgagctca tcgacggctg ccgcgccgac gtgctcggca cgacgtacga gacgttcgac
    11221 gagctgcacc actactgccg gtgcgtcgcc gggtcgatcg gcaggctctc gctggccgtg
    11281 ttcggcggcg cgcacccgcg gcgtgacgcg cggctggccg acgacctcgg catcgcgctg
    11341 cagctgacca acatcctgcg cgacgtgctg gaggaccgcc gcaacggccg gatctacctg
    11401 cccgccgagg acctgcgccg gttcggctgc accctcgacc tcgacgaggg cggatggctc
    11461 gccgactccg aggaggcgct gctgcccctg ctggagtacg aggccgccag ggcggaggag
    11521 tggtacggcc gcgggctggt gctgctggac tccctcgacg cgcgcagccg cgcgtgctgt
    11581 gccgcgatgg cgggcatcta ccaccggctg ctgcggcgga tggcgctgcg gcccggcctc
    11641 gtcctgcacg gccgcacgtc gctgcccgac tgggagaagc tcaccgtggc cgcgagagcg
    11701 ctcgccgggg cgcggccatg agcgcgcacg tggtggtcgt cggtggcggg ctcgccggcc
    11761 tgaccgccgc gtgcgacctc gccgacgacg ggctgcgggt gaccctgctc gaggcgcggg
    11821 gcaggctggg cggcgccacg ttctcgttcc gccgcgacgg tctctccgtc gacaacggcc
    11881 agcacgtgct ccttcgctgc tgcaccgagt accgggcgct gctggcccgc ctcggcacgg
    11941 cggagggcat cgcgatgcag gagcggttcc gcatgccggt gctcgcgccc ggcgggcggc
    12001 tcaccgagct gacccggacc tgggggcccg cgccgctgca cctggtggcc ggcctggccc
    12061 gttacggcgc tctgccggtc accgaccggc tccgcgcctt ccgcgcggcc gccgccatgc
    12121 gcctgctcga ccccgatgac cccgcgctcg acgagcgcgg cttcggcgac tggctgcgcg
    12181 ggcacgggca gaacggcgcc acgctcgccg cgctgtggaa cctgatctcg gtggcggcgc
    12241 tcaactgcga cgccgatgag gcctcgctcg cgctcgccgc gaaggtgttc cgcaccgcgc
    12301 tgctcgaccg cgccgacgcc gccgacatcg gcgtgccgcg gtggccgctg gaggacctgc
    12361 acgtccgccc cgccgagaag tacctgctgg cccgcggggc cgagatccgc acgcgcagcg
    12421 cggtgcgggc ggtggagcga cgcgatcgcg gcttcgcggt gcggctcgac ggcgagacgc
    12481 tcaccgccga cgccgtcgtg gtggccgccc cgccggagcc ctcggcgaag gtgtgcccgg
    12541 ccgaggccgg ggtctccggc gcgcggctcg cggggcttgg cgcggcgccg atcgtgaacg
    12601 tccatgttgt ctacgagcgg cccgtcaccg acctgccctt cgcggcgacc accggctcgc
    12661 ccgtgcagtg gatcttcgac cgcacggacg tcgccgggct cagcgcggga cagtacctga
    12721 cgatctcgct gtccgcggcc catacctggc tcgacacccc cgtgcccgag ctgagggaga
    12781 tcttcctgac ggagctgggc aggctgctgc ccgccgccag gaccacgcca tgcacgcggt
    12841 tcttcgtcac ccgcgaacgg cgggccacct tccggcaggc gccgggcacg gggcggctgc
    12901 gcccccagcc ggagacccgg ctgcccggac tcgtgctcgc cggctcgtgg accgccaccg
    12961 ggtggcccga cacgatggag ggagccgtgc gaagcggaca ccgagcggcc ggactcgtca
    13021 gcgcacacgc ctggggaggt gcgcgatgac cgcgacgctg ccctccgagg tgaccgccac
    13081 ccaggcgctc gtgcagcccg cactgcgcga cgcggtgggc gagctgcgcc cgccgatgcg
    13141 ccggatcgtc agctaccacc tcggctggac cgacgagcac ggccaggcgc gcaacggtgg
    13201 tggcggcaag gcgctgcggc ccgcgctggc gctgctcgcc gcgcaggccg tccgcgcagg
    13261 ccccgaggcg gcactgcccg gggcggtcgc cgtggagctc gtgcacaatt tctcgctgct
    13321 gcacgacgac gtcatggacg gcgacctcga gcgcaggcac cggcccaccg tgtggcggct
    13381 gttcggcacg ccggccgcga tcctcgccgg cgacgcgctg ctcacgctcg cggtggacgt
    13441 gctcgaacgc gccgccgacc ccaccgccac ccgctgtctc accgcgtcgg tgcaggacct
    13501 gatcgcgggc cagagccagg acgtcgggtt cgagactagg atggacgtcg gcctcgacga
    13561 gtgcctggag atggcggcgg gcaagaccgc ggcgctcatg cgctgtgccg ccgaggtcgg
    13621 ggcgctgctc ggcagggcga gcccggtggc ctccgggctg ctcgccgaat tcggccgctg
    13681 tctcggcatg gccttccagc tcgtcgacga ccttctcggc atctggggga gtcccgacgt
    13741 caccgggaaa ccggtgctgg cggacctgcg cgtgcggaag aagtccgtgc ccgtggtcgc
    13801 cgcgctggac tccggcaccg ggcccggcgc ggcgctgcgc gagctgtacg gcagacccga
    13861 tccgcccacg gaggaggagc tccgcacgat ggcagagttg atcgagcggt ccggcgcgct
    13921 ggcctggacc cgcgaccggg cgcagcgcta cgtcgtggag gcgaggtcgt gtctcgaccg
    13981 cctcgccccg cccgaaccca tccacgccgc gctgagcgat ctcacgcggt tcgtcgtgga
    14041 gcgtgaccgg tgagcggcgt gatcgagcgg acgacggccc ccgccgcggc gagggaggcg
    14101 gccgagcggg cccgcgagta cctgctctcg ctccagcacg aggaaggctg gtggaagggc
    14161 gagctcgaga ccaacgtgac gatggacgcc gaggacctga tgctccggcg cttcctcggc
    14221 atcctcgacg agcagacgct cgccgagtcg gcgcggtgga tccgctcgtg ccagcgggag
    14281 gacggcacgt gggccaactt ccacggcggt cccgccgacc tctccaccac cgtcgaggcc
    14341 tatgtcgcgc tccgcatggc gggcgacccg gtcggctcgg agcacctgcg caaggcgcgc
    14401 gagtacatcc tcgcccacgg cggtatcgag gccacccggg tcttcacccg catctggctc
    14461 gcactgttcg gcgagtggtc ctgggacgag ctgcccgtgc tgccgccgga gatggtgctg
    14521 ctgccggact ggttcccgct caacatctac gactgggcgt gctgggcccg gcagaccgtg
    14581 gtgccgctga ccgtggtcgg cgcggcgcgg ccgtgccgcg cgctcggcgt gagcgtgcgg
    14641 gaactgcgca ccggacggcc gggaccggag ccggcttcgc tgctgacgtg ggcgggggcc
    14701 ttccagcgcc tcgacggggt gctgcacgtg ctcgagcgcg tccccgtcaa gccgctgcgc
    14761 ggcgtcgcgc tggcccgcgc ggaacggtgg atcctcgacc ggcaggaggc ggacggcggg
    14821 tggggcggca tccagccgcc gtgggtgtac tcgatcctcg cgctgaacct gcgtggctac
    14881 ggcacggacc atccggtgct gcgcaaggca ctcgacgggc tcgacgggtt cacgatccgc
    14941 gagcgcaccg ccgagggcat ggtgcggagg ctggaggcgt gccagtcgcc ggtgtgggac
    15001 accgcgctcg cgatcatcgc gctgctcgac gccggactgc ctcccggcga cccggcgctc
    15061 gtgcgcgcca ccgactgggt gctgcgcgag gagatcagga gcgacggcga ctggagcgtg
    15121 cgcaggccgg acctgacgcc gtccggctgg gcgttcgagt tcgccaacga ccactacccg
    15181 gacaccgacg acacggccga ggttgtgctt ggcctgaacc gcgtccacca tcccgagccc
    15241 gcccggctcg gcgaggcgct cgaccgggcg gtggcgtgga ccaccggaat gcagtcgcgc
    15301 gacggcggct ggggcgcgtt cgacgcggac aacaccagga cgctgccgga gaagctgccg
    15361 ttctgcgact tcggcgccgt gatcgacccg ccctcggccg acgtgaccgc gcacatcgtc
    15421 gagatgctcg ccgcccgcgg tgaggcggac gcccagcccg cgcggcgtgg cgtgcgctgg
    15481 ctgttgcggc accaggaacg ggacggctcg tggttcggcc ggtggggcgc gaaccacgtc
    15541 tacggcaccg gtgccgtcgt gcccgcgctg gtcgcctgcg ggatcccggt gacgcacccc
    15601 gcgatccgcc gcgcggtcgg ctggctcacg cggcaccaga accccgacgg cggctggggt
    15661 gaggacctcc ggtcctatgt ggacccggcc tgggtgggca agggcgagtc cacggcgtcg
    15721 cagacggcgt gggcactgct cgcgctgctc gccgcggggg agcgcggcga tcccgtggtg
    15781 cggggcgtcg agtggctcac tcgcacccag cgggaggacg gcggctggga cgagccctgg
    15841 ttcaccggca ccggcttccc cggcgacttc tacatcaact accacctgta ccggctcgtc
    15901 ttcccgctca tggcgctcgg ccgatacgtg gaggtgacca gcgatgaaac caccggatga
    15961 cgacctgatc gtcgtctcgc cgctgctgct ggaggcccgg agcgtccggc ggggcctgcg
    16021 cggtccctcc ggtgggcacg tggtgctcgc gggaccgcac gcgcgccggg ccaaacgcgt
    16081 cgcacgggcg ctgcggcagt acccggaccg gccggtggcc gtcgcggggg tcgccggcgc
    16141 gctcgtgcac ggcctccggc cgggggacct ggtggttgcg agcgaggtcc gctccgcgca
    16201 gggcacgcac cactgccggt cggcgccgct gctcgcggca cagctgcgca agctcgggct
    16261 gaccgtccac gtcggaccga tggtggagac cgaccacgtg gtgtggcaac cggagggcgc
    16321 gcggctcgcg ctcgacgggg cgatcgccgt ggacatggag tccgcgcggc tgctggacat
    16381 gatcgggtcc cgtcccgccg ccgtggtgcg ggcggtggtg gacaccccca cgcggtcgct
    16441 gctgcacccg gcgaccgtgc cgggcggcat cgccgcgctg cggtcgctgc gggcggtcgg
    16501 gcccgcgttg cgccggtggg cggccgcgac cggcgaccgc acggtgctgc tggccggccc
    16561 gcgatcgttc tgcgccggtg tggaccgggc ggtggagatc gtggagcgcc tgctcgaccg
    16621 gcacgcgccg ccgatctacg tgcgcaagca gatcgtgcac aactcgcgcg tggtgggcga
    16681 gctggaacgg cggggcgcgg tgttcgtcga cgaactcgac gaggtgccgg agaacgcgac
    16741 cgtcgtgttc tccgcgcacg gcgtctcccc ggcggtgcgg gaggccgccg aggaacgcgg
    16801 gctcgacgtg gtggacgcga cgtgcccgct cgtggccaag gtgcacggcg aggcgaggcg
    16861 gttcgcccgc gacggcgaca ccgtgttcct catcgggcac gccgggcacg aggaagtgga
    16921 ggggacgctc ggcgaggcgc cggaacgcac cgtgctcgtg gagcggccgg aggacgtcgc
    16981 gggactcgag gtcgaggacc ccgaccgcgt cgcctacctc atgcagacca ccctcgcgat
    17041 ggacgaggcc gcgggggtgg tggacgccct gcgcgaccgc ttcccggctt tgcggggtcc
    17101 cggctcggac gacatctgct acgccaccac caaccggcag gacgcggtgc gcgtggtggc
    17161 gcgcgagtcg gatgtcgtgc tcgtggcggg ttcgggcaac tcgtccaact cccgccgcct
    17221 cgtggaggtg gcccagcgtg agggcgccag ggcctacctg gtggacaacg tgaacgagat
    17281 cgacctcgat tggctggtgg gcgcccgcac ggtcgggctg tccgccggcg cgtcggcgcc
    17341 gacggtactg gtggacgaga tcgtcgacgc gttggccggt ctcggggcgg tggagacgag
    17401 ggagcgcacc accgcgaccg aaaccgtgaa cttcagcctt cccaaggagg tgcggcaccg
    17461 atgaacatgc ccctgcacca ggcgatccgc gtggcgaggc acgtggccac ccagaagctg
    17521 cgcaagcgcg acaagttccc gttcatcatg gagctcgaac cgatcctggc ctgcaacctc
    17581 aaatgcgggg gctgcgggaa gatccagcac ccggccaaca tcctcaagca gcggatgccc
    17641 gtcgagcagg ccgtcgccgc cgtggaggag gccggcgcgc cgatggtgtc gatcgcgggc
    17701 ggcgagccgc tcatgcatcc cgagatcgac cggatggtca acgagctcgt caagcgcaag
    17761 aagtacgtct tcctgtgcac caacgcggtg ctcctgcgca agaagatcga caagctcgac
    17821 ctcaagccgt ccaagtactt cgcgttcacc gtgcatctcg acgggctccg ggagcggcac
    17881 gacgcggccg tggcgaagga gggcgtgttc gacgaggccg tcgcggcgat ccgggagctg
    17941 aagcggcgcg ggttccgcgt caccaccaac acgaccgtgt tcaacacgga caccccgcag
    18001 agcgtcatcg acgtgctcga ctacctcaac gacgagctcg agatcgactc gctcatgctg
    18061 tctcccgcct acgcctacga gaaggcgccg gaccaggagc acttcctcgg cgtgcaggag
    18121 accagggagc tcttccggaa ggccttcgcg aacggcaacc gcaagcgctg gcggctcgtg
    18181 cactcgccgt tgttcctcga cttcctcgag ggcaaggtcg atttcgagtg caccgcgtgg
    18241 ggcgtgccgc tgtacacgct gttcggctgg cagaagccct gctacctcat gggcgacggg
    18301 tacgtgaaga cgtaccggga gctggtcgag accaccgagt gggagaagta cggccgcggc
    18361 cgggacccgc gctgtgccaa ctgcatggcg cactgcgggt acgagccgac gtcggtactg
    18421 gcgaccatga gctccctgaa ggagtcgatc cgcgcggccc gcgaaacctg acgccgagcc
    18481 cgcgagtccc ccgctccgac ccgcgagtcc cccgctcggg cccgcgagtt gcccgctcgg
    18541 ggcctgcgag ttgcccgctc gggcccgcga gtcccccgct ggggcgcgtg agttgcccct
    18601 tccggacccc gagtcgtgcg ttgccgaacg cgcgaacgca gggccggcgg tccggagcgg
    18661 gggactcggc gtccggagtg cagaactcgg cgtccggagc gggggactcg cgggctggag
    18721 cgggggactc gcgggttcag gcgaagcggc gttgcagggc gtcggtgagg gccggcgcca
    18781 ctccgcgcag gcgtgcgggc aggcgaagcc agcggggcac gaacacctcc gcccgattcc
    18841 gctcgacggc ggcgacgagg gccgccgcca ctcgctccgg gggtaccggg cgcgggctgt
    18901 gccgcgtgta cggcgtaccc cggcgcgcga agaacggcgt gtcgaccacg cccggcacca
    18961 ccaccgacac gcccacgccg cgaccggcca cctcgccccg cacgctcgcg gcgaacgcgt
    19021 ccagccccgc cttcgtcgcc gagtagacgg cctcgcccgc gacgctcatg ctccccgcga
    19081 tcgacgagac gaacacgaga tgcccgcgcc cgcgctccac catccccggc agcaccgccc
    19141 gcaccaacag gatctgcgcc agcaggttca cgcgcacgag ggtctcggcg tccgcctccg
    19201 gcatgtcctc gaggcgtccc gcccagccga cgcccgcgtt gcacaccagc aggtccacgt
    19261 cgcccgcgga ggccagcacc cgcgcggcgg caccggaacc ggcgaggtcg gcggcacacg
    19321 cacgggcacc ggtgcgccgc gcgacggtct ccagcgccgc ggggtcgcgg ccggtcacca
    19381 gcacgtcaca tccacgccgg gcaagcaccg acgccgtcgc ggcgccgata cccgacgaac
    19441 cgcccgtcac caccgcggtc gttccggctc cgatcacccg ttctcccttc ccggcgtgct
    19501 cacctgcggg gcccgctggc tgagcagcgc gatgccggcg atggcgaccg ccagcccgag
    19561 cacctgcccc gcgatccttc cggcgccgcc cggcagctcc tcgccgagcc acagcgcgcc
    19621 gaccccgatg ctgacgagcg ggtcgagcga gacgatcacc gcgagcgcgg gagccagcgc
    19681 caccccgacc cggaacgcgt tctggctcaa caggaacccc gtcaccccgc acaccaccac
    19741 gacgtagaaa tgccagtgcg tcagcagcgc caccacaccg cgccggaggt cgtcggcggc
    19801 gagcttggtg acccccgccg tgacgccgta cagcaccccg gtggccgtcg ccagcgccag
    19861 gacccgcacc cggccagcga accgtaccgc gagcccgacc gcgacggcga tcatcgcggc
    19921 cagccctgtc gccagcggca ggacgtcgcg cagctccagc gtgccgtgcc cggcctccgg
    19981 tctggccacg aggaagaaca acgccagccc cgccacacac agccccgccc cgagcagcac
    20041 caggccgtcc gggcgctccc gccgcagcgc gctgctgctg aacaccgcga acaccagcga
    20101 cgtcacgagc agcggctgca cgaacaccag cggcgcggtg ctgagcgcca gccactggaa
    20161 cacgatcccg agcccgttgg ccagcagcga ggccagccac agcggctgcc gcagcagcgt
    20221 gaacaccagc ccccatcgca cggggccccc gccctcgacg cgacgggccg ccctgtgctg
    20281 cagcgcgccg gtcacgccga acgccgccgc ggccaggatc gcggcgggca ccgcgatccc
    20341 caggacggtg tcctggccgg tcatgggccg gcgtggtcac cggccagctc ggcgaggagg
    20401 gcgtcggtgc gcgcggcgat cccgtcgacg aacgcggcct gcgcgggggt gcccgtgaac
    20461 accatcgtga tccagcgccc ccacgtcatc gcgccccacg cgagcccgct gccgggcgcc
    20521 agcgcgagca cggggtaggc ctccgacatc accgacccgt gccagcggat ctcccgccgt
    20581 ggccccggca tgacggtgcc gatcgcgttg aaccagtcgc ctcggtagac gctcctggcg
    20641 gcgagcgcgt gcagccgggg cggcagcctg ccgatgaggc gcaccacggc gtgcgcggcc
    20701 tcgggcaccc cggcgtcgat gcgctcccgc agcccgttgg ccacgagcga agcccgggtg
    20761 cgcaggtcca tcgggccgac cggcaggtcc accgacaccg ccccggtgtg gttgcccgcc
    20821 gcgcgcaggc tcccggtgcc acgcagggac cacggcgcca tcagccggaa ccgcgcgccg
    20881 ggctgcgctc cgagcacgtc gtgcacggcc tcggcgaaca ccgctttgag caggtcggcc
    20941 ggtgcgacgc cgagggcgcg ggcggcctgc cggacctcct tgcccggcag ccgtacgacc
    21001 gcgtggtgac ggtcgggtcc ggtgatcgcg acgtccagcg gcgtcgcggg cgccctgccc
    21061 gcccgcgcca gctcccacag ccctccggcg agcttgcccg gagcgggccg gaaaccgttg
    21121 ccgcccaccg aggtcgttgg ccggatcgcc caggagagcc cggtgctggt gtcggtgtcg
    21181 gacagcaggg cctgcagcac ggtcatcccg tcgcccagcg cgtggtgcag cttgacgagc
    21241 agggctcgcc gctggccggg caggcccgtc accagccgtg cggcaccgag cgcgcgggtg
    21301 gtgtcgagcg gcacggagaa gaacgcgtcg acggagcggg ccagatcacc ggccacgacc
    21361 tcgtcgacca gcgaaagcgg gtcggcgtcc tcgccggggt cccagcgcgc ccgtcgcacg
    21421 agggtcgccg ggagcagcct gccgccgacg cccggcaccg cggcgagcat tccggcggcg
    21481 tccttgcgcg tgagcggcgg ccccggttcg aacaccagcg ccgtgccgac gtactgcggc
    21541 acctctggag tgctggcgtg caggaagagc gcgtcgggcg cgggcagcgg acgtgcccgc
    21601 gccgcaccgg gttgccgggc gaatacgcgc aggtcgtcgt cgagccggtg agcgctcgtg
    21661 tgccggcggg ccgcctcctc cagcgcgcgc aggcgctccg gccgggtcac cagctcgcgc
    21721 accgtgcggg ccagctcacc cggccccgcg cacaccctgg cgagtcccgc ctcctccagc
    21781 aggcgggcgt tggccttgcc gtgtcccggg atcgggtcgt gcagcaccac ggcgcgaccg
    21841 cacgcgagcg cctccagcgc cgtcgcgccg cccgcgttgg tcaccaccag gtcggccgcg
    21901 gtcatgagcg tggccatgtc gtcgacccag cccagcaccc gtacgcgctc gtcgccggcg
    21961 aacccgcgtt ccagccggcg ccgcaggcgc tcgtcgcgcc cggtcaccac cacgacgcac
    22021 gcggccgggc cgccgcccag cagctcccgg acggcgccgc tggggtcgcc gaaggccagc
    22081 gagccgcacg acacgacggc cagcggcccc gcgtccggaa gccccagccg ttcccgtgcc
    22141 gcgccgcggt caccgggagc gaaccgtcct ggcacagggg gagcggacac cgcgaccggc
    22201 gcgccgggca cgctgcgccg tgcggcctcc acggccacct cgtgcatgac catgtttacg
    22261 gtcacgccct cgtgcaccca cgacgggtgc ggcgcgatgt cggagaccca cgccgccgtc
    22321 ggcaccgaca gtccccggtg cctgcgcagc cactccagcc cggtgctgcc catcgggtag
    22381 gtggagacga tcgcgtcggg gcgggccgcg tcgatgacgg aagcgagccg ccgcccgctc
    22441 cacgcgccga tcacccgctt ggcggctttc gcgaaccagc ggtggtgcca caccgaggtg
    22501 tagaagaact cgtagagcca cggcagccgc tcgacgctcg tcgcgtagat ccagcggaac
    22561 accggtccgg tgccgcggcc catcacgtcg agcacgtcgg cccactccac ctcgatgccg
    22621 ggccacaccc gttgcgccgc cgcccgcagg gcgcgcgcgg tcgcgttgtg gccctcgccc
    22681 atggtcgccg agacgatcag caaccgggct gggccctccg cctccggact cgcgctcgtc
    22741 gtcaccaccg cccatccgtg cccgctgcca ggattcaatc acgattcccg ggcgagcgtg
    22801 accctctgga gtggacggct gtagcgcgtg tcagccgaga aacaccacgg agaacacggt
    22861 ggcggccagg agccccgcca tgacggggag gaagcagcgg cgggcgaggt cgagcacggg
    22921 caccctggcg aacccggcca ccgcgatgag cgacgaccac gcgacgagcg tcccgccacc
    22981 ggaccagatg ttgcccatct ggccgagcgc ggcgagggtc gtgtcgtcga tgcccgcgcc
    23041 ggcgccgagg ctgcccgcga gcgcgcccgt gagcggcaga ccggagaaac cggagccgtc
    23101 gagaccggcg accacgccga cgagcaggat cgcgaaagcc gcgatgaacc cgttctccgg
    23161 aatgtggtcc tgcaccgcgg ccacgaggtc gaacaggatt ccctggcccc ggatctcggt
    23221 gccgaggatc tgggaggcga actcggcgtt gccgatgaag aagaagccgg cgatgggcag
    23281 cacgatcccc atcgccttga atgcgaagac cagcccgttc accacgtggg ttgccgacgt
    23341 ttccaggaag ccgcggccgt cgccgacgag ggccgccatg aagacgatga gcgccgcgac
    23401 gccgccgacg agcccggcgg cctggccgga ctccaggtcg ggcacgctcg gtgagatctt
    23461 ggcgacgatc atgtagccga tcagggacag gtaggcgagg ggcacgaaga cggcgaagaa
    23521 cgtcgatgcc ctcgggtact cccgtgccgg atcggcggaa gccgggtcac caccgtccac
    23581 agtgtccggt gagccgccaa ggagcggtgc ggccggcgga ggttccgtgc cgtcgccgtc
    23641 agaggccaca cgcgccccgg ctccggtggg caccagctcg cgctgcctcg gcgctgcctc
    23701 ggcggtttcg gcggcctggc gcggttccgg cgtggcgaac tgccggccgc tcgcctccca
    23761 ttcggtgagc agccgcgccg agggcttgcg catcttgcgg aactcgagcg cgtaacccac
    23821 gagcagcgcc acgccgccga ccaccagcga gagcaccatc gccttgtcgg ccaccgcgtt
    23881 cgggtccatg ccacccgcct gcgcggagag cccgggtgcg acgcggatga cgtagtccga
    23941 cgacagtgcc atgccctgtc ccgcgcacgc catcaccatg cccaccgcca tcggccgcag
    24001 gcccgcgcgg atcgcgacgg gcacgaggac cgcgccgatc agtggcaccg cgggcgttgg
    24061 ccagaagaac agcgagatga agtaggtgac caccaggagt gcccagaacg ccagatgccc
    24121 gttgcgcatc acccggcgga agggcgccac catcttccgg tcggcgccca gaacctgcag
    24181 cgaatggagc atcgcggtca cgagcgcgat gatcaggaag atgttgaaca ggttcgtcgc
    24241 ggcgaccagg ctcgcgtcga acaccgcggt gatgccggtg atcaggctgc cggagaacac
    24301 cagcgcggtc aggaacgtcg ccgccacggc ggggacgacg atgttcttcc tggccatcat
    24361 cgtgccgaga atgacgatga caccggccag gtatatccag tgggcggctg tgagtggcat
    24421 gggcttccct tcggctggaa gtcatggcgt taacggaaga ggttccgcgt gcgggcggtg
    24481 tcccgtctac cagtcatgtg cacaccgcgc ggggccaagt ttgtgcacgt tgccctggtg
    24541 ccaccggttg taaccggggc agtctgaaat ggatctcggc gcaaccgcac cgtaaccgcc
    24601 gcgcgacatg gactggcccg gtgcgtgctc gcccgcgagt cctggaggtc cgttccggtg
    24661 ggggaagtcc gcacgcccgg tgcccgggtg ttgtgcacac tgctggcggt gacgctgctc
    24721 ggcaccgtct gcaacaacgt gctcaacgtg ccgttgcgcg agatctcgct cgacctcggc
    24781 gtgccgctgc ccgcgggtgt gcttgcggtg agctccttcg cgctggtgct cgccgtgacg
    24841 atgccgctgg tgggctgggt tggtgaccgt gtcggccgca cgcgcacgct gctcgtcgcg
    24901 caggtgctga tggcctgctc gatggcgggt gccgcgctcg cgccgtcgct gccggtgctc
    24961 gcggtgtgcc ggggactcca ggggctcgcg tgcgcggcgg ctccgccgtg cgtgatgggg
    25021 ctcctggcga gcctctacgg cccccggcgg cgtaaccgcg tgatgggcgc gtgggcggcg
    25081 gccaacggcg tgggccaggc actcggcccg ccgctcggcg ggctcgtggc cgaatcactc
    25141 ggctggcggg agatcttctg ggtactcacg ccggtgagcg tgttgctggt ggccgcgctc
    25201 gcgtggctgg tgcccgcaga gccggccagg cccgcgcgcc tgcactggcc gggcacgatc
    25261 acgttcacgc tgggaaccgc cctgctcatg gcggcggccg ccctcgcacc gggcgcgacg
    25321 atcccgttgc cggtgctggc cgggctcgcc gccgcgggca ccggcttgct gacggcgtac
    25381 gccctgctgt cccgcaacgt cgcggacccg ttcatcccgc cccggctgat cacggagacc
    25441 cgattcctgc gcagcgggtt cgccgcatgc gcacagatgt tctgcctcgg cgcgacgctg
    25501 gtcgcgatgc cgttgtacgc cacgggttcg ctcggactgc gcacggcgat ggcgggcctg
    25561 ctggtgttcg cgctgccgct taccatggcg gtgctggccg gcgtggtcgg cgtgctcagc
    25621 gagcgcaccc ggccccgctg ggtgctccgc gccgggctgg cgctgctggt ggtcgcggag
    25681 atggcgatcg gctgctacgt cggcgcccgc ggccagagcc tcgcggcggt ggcggcgttg
    25741 ctggccgcga tcggctgcgg ggtcgcgctg gtgcagaccc cggcggccgc cggagccacc
    25801 cgctcggcag cgggaagcgc gggtgccgca ctcggcctgt tcaacacgtt gcgcttcggc
    25861 ggggcggccc tcggcgtggc gtgggtcggc ctgatgtacc ccgtggtctc gccgccggtg
    25921 ctcttcggcg ggtgtgccgt gttcgcgctc gccggcctcg
//
