LOCUS       NZ_SWMS01000004        21560 bp    DNA     linear   CON 10-DEC-2024
DEFINITION  Prauserella endophytica strain CGMCC 4.7182 Scaffold4, whole genome
            shotgun sequence.
ACCESSION   NZ_SWMS01000004
VERSION     NZ_SWMS01000004.1
KEYWORDS    WGS; RefSeq.
SOURCE      Prauserella endophytica
  ORGANISM  Prauserella endophytica
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Prauserella; Prauserella
            coralliicola group.
REFERENCE   1  (bases 1 to 390627)
  AUTHORS   Liu,J.M., Habden,X., Guo,L., Tuo,L., Jiang,Z.K., Liu,S.W., Liu,X.F.,
            Chen,L., Li,R.F., Zhang,Y.Q. and Sun,C.H.
  TITLE     Prauserella endophytica sp. nov., an endophytic actinobacterium
            isolated from Tamarix taklamakanensis
  JOURNAL   Antonie Van Leeuwenhoek 107 (6), 1401-1409 (2015)
   PUBMED   25832628
REFERENCE   2  (bases 1 to 390627)
  AUTHORS   Li,Q.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-APR-2019) Yunnan Institute of Microbiology, Yunnan
            University, No. 2 Cuihu North Rd, Kunming, Yunnan 650091, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 10.16x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_005146945.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 16:32:08
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,852
            CDSs (total)                      :: 7,795
            Genes (coding)                    :: 7,703
            CDSs (with protein)               :: 7,703
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 34 of 92
            Pseudo Genes (incomplete)         :: 69 of 92
            Pseudo Genes (internal stop)      :: 2 of 92
            Pseudo Genes (multiple problems)  :: 13 of 92
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 18:09:25
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 188449
            Orig. end                         :: 210009
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            SWMS01000004.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21560
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21560
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21560
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11560](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11560)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            86..895
                     /locus_tag="FCN18_RS10095"
                     /old_locus_tag="FCN18_10095"
     CDS             86..895
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005462043.1"
                     /locus_tag="FCN18_RS10095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_10095"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_112271636.1"
                     /transl_table=11
                     /translation="MRLGRISLTAFTWLVAILFVFPVIWMVLTSFKTEADAYTDPPRLF
                     FSPTLEQFAGVFERGFLPYLANSAFVTVVSTLAVLVLAIPAAYALSIAPVKGTSNVLGF
                     FLSTKMLPIVAAIIPLYVISQNVQLLDNVWALNILYTAMNLPLAVWMMRSFFLEVPKEM
                     IEAARVDGAKLPTLLYKVVLPVVAPGIAATALICVIFSWTEFFYAVNLTAARAGTVPVF
                     LSGFITSEGLYWAQLSAAALLASLPVMIIGWIAQNHLVRGLSMGAVK"
     gene            1082..1903
                     /locus_tag="FCN18_RS10100"
                     /old_locus_tag="FCN18_10100"
     CDS             1082..1903
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1292: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009152825.1"
                     /locus_tag="FCN18_RS10100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_10100"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_137094609.1"
                     /transl_table=11
                     /translation="MSSDSAAVDSEIVVLDNGVPTAARVYDVMLNGKDNYAIDRQVAEA
                     SLSVMPELKEIALHNRAILHRVVRHLAAEQGITQFLDLGSGLPTARNTHEVAQEANPDA
                     KVVYVDIDPIVLAHGRALLQDNENTRVVTADLRKPEEVLSHPDVQEMIDFSKPVCVMLC
                     GILHHLADDEDPKGIVQALREAVVPGSYFFITNFTRLSDSPESEELEKVLLSQLGTGRV
                     RTPAELEEFFEGLEILAPGIVPLPLWRPDEIVTDATTIGVRFMTGGVGRKN"
     gene            complement(1988..2539)
                     /locus_tag="FCN18_RS10105"
                     /old_locus_tag="FCN18_10105"
     CDS             complement(1988..2539)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005151102.1"
                     /locus_tag="FCN18_RS10105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_10105"
                     /product="hemerythrin domain-containing protein"
                     /protein_id="WP_137094611.1"
                     /transl_table=11
                     /translation="MTDDLISVIMNDHREVERVFAELEDKATDPRRRRELADHVIAELV
                     RHSVAEEQFMYPAARKHLENGNELADHEIEEHSEAELLMKQLEDMDATDPKFDQLLGNL
                     MDSIRHHVEDEENDLLPKLRAACSEEELRELGEKVLRAKEKAPTRPHPQSPDKPPANRI
                     LDPGAGLIDRMRDKLSGRAT"
     gene            complement(2608..3678)
                     /locus_tag="FCN18_RS10110"
                     /old_locus_tag="FCN18_10110"
     CDS             complement(2608..3678)
                     /GO_function="GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005454069.1"
                     /locus_tag="FCN18_RS10110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_10110"
                     /product="AI-2E family transporter"
                     /protein_id="WP_323808351.1"
                     /transl_table=11
                     /translation="MHANGYPHRMSKPRLRLSAGMLRSAAIVSAELLLLFLALWALRNV
                     VEHLSYVLIPMSIALLLSAFLQPLVGFLCRHRWPRGLAVVTSLIAGLTVAGGLVAFVVL
                     SILNNFDELRLQVAESIAQVEDWLRRGPFQFEGGLSDRVQEWLGGNQQAVISQALGAFS
                     TVSAIGIGLLLSTVLLVIFLYDGPRMWEFLLRPFRTSTRNVIDESGRRAYRSVVTYVWV
                     TALVALIDAIGIGIGLAIVGVPLTVPLAALVFLGGFVPYVGSVVSGFVAVAVTLVSNGG
                     VAALIILGVVLGVQQLEGHVLQPVLQGNLSKLHPAVVLVALVIGGTEGGIAGVLFAVPT
                     VAAVKAVLITVAEHRA"
     gene            3781..4083
                     /locus_tag="FCN18_RS10115"
                     /old_locus_tag="FCN18_10115"
     CDS             3781..4083
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009152837.1"
                     /locus_tag="FCN18_RS10115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_10115"
                     /product="DUF3040 domain-containing protein"
                     /protein_id="WP_137094613.1"
                     /transl_table=11
                     /translation="MLSHYERQELERIAQRFEHDDPELASALGSCAHPRGTLRLSKLAR
                     LGLDLFAGVLVVLGALTLNFGLVFVGALLLICAACAHLKGWSPIDPPPTQYRRME"
     gene            complement(4144..4986)
                     /locus_tag="FCN18_RS10120"
                     /old_locus_tag="FCN18_10120"
     CDS             complement(4144..4986)
                     /EC_number="6.3.2.6"
                     /GO_function="GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007026827.1"
                     /locus_tag="FCN18_RS10120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_10120"
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="WP_137094796.1"
                     /transl_table=11
                     /translation="MSRVKHIHAGKVRDLYEDGGDILLVASDRVSVYDVTLPTPIPGKG
                     ALLTQLSLWWFERFGDVVPNHVLSGTDVPPEFARRAIRCKPLEMVKVECIARGYLAGLG
                     LKEYQKYGTVSGVALPPGLEEGSELPEPIFTPTTKAEVGHDEFITFDDVVRQEGRETAE
                     RLRDLTLEIYRRGAAHAETRGILVADTKLEFGRDADGTLTLADEVLTSDSSRFWPADEW
                     QPGRTQHAFDKQFVRDWATSTDWDRTPPGPEVPPEIVEATRARYTEAYERITGNTWTG"
     gene            5058..6848
                     /locus_tag="FCN18_RS10125"
                     /old_locus_tag="FCN18_10125"
     CDS             5058..6848
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055: pyruvate oxidase/decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005448857.1"
                     /locus_tag="FCN18_RS10125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_10125"
                     /product="thiamine pyrophosphate-requiring protein"
                     /protein_id="WP_113641002.1"
                     /sec_met_domain="TPP_enzyme_N (E-value: 3.6e-47, bitscore:
                     154.7, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1e-30, bitscore:
                     101.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAETVGDQVVRRLREWGVEHVFGYPGDGINGIVTAFGKADNQPRF
                     VQSRHEEMSAFQAVGYAKFSGEVGVCLATSGPGAIHLLNGLYDAKLDHVPVVALVGQTA
                     RTAMGGSYQQEVDLQALYKDVAAAYLVEVNVAEQLPNALDRAFRTARARQAPTAVIIPA
                     DLQEQDYSPPQHAFKQVPSSPPSSPHAVLVPPEDELARAAEVLNAGEKVAILVGQGARN
                     AADEVKHVAELTGAGVAKALLGKDVLPDDLPYVTGSIGLLGTRPTYELMQECDTLLIVG
                     SNMPYSQFLPEFGQARAVQIDVDASVIGMRYPTEANLVGEAKGTLRALIPLLEAKDDRS
                     WRRDIERNVAAWWETMEQQAMLEARPVNPQRVVHELSARIPEDAIVTADSGSSTNWYAR
                     NLRIRGRMRASLSGTLATMGPGVPYAIGAKFAHPERPVVALVGDGAMQMNGMAELITIA
                     RYRELWSDPRLVVCVFHNDDLNQVTWELRAMGGAPKFEESQSLPDVSYAGFARSLGFEG
                     IAVDDPGELGPAWDRALSADGPVVLDVRCDPEVPPIPPHATFEQMKSTAEALLKGDPNA
                     WHVLVQGAKTKMQEFVPGRR"
     misc_feature    complement(5059..5073)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     gene            7039..7842
                     /locus_tag="FCN18_RS10130"
                     /old_locus_tag="FCN18_10130"
     CDS             7039..7842
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1292: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007026826.1"
                     /locus_tag="FCN18_RS10130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_10130"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_137094615.1"
                     /transl_table=11
                     /translation="MALPVPATDQQKAEQPSIARVHDCWLEGSHHSDLDRQYADQIALC
                     APHVPYLVRESRQLLRRMVGFLVEQGVRQFLDLGTGIPTRGHVHEIAQELDPSCRVVYV
                     DNDPRVAADGAKVVADNGGAAFVQADIRRPDEIFGAKESRELLDRSRPVAVLLVETLLF
                     LRDEEDPAAVVKAYVDAVCPGSYVGIVHFSQNEELDQGLNLFSRMFGAPPIVTLRDRDV
                     LVDFFAGLDLVEPGIVPVPLWRPEDEDPVLNPEAVQVHAGLGRKP"
     gene            complement(7861..8778)
                     /locus_tag="FCN18_RS10135"
                     /old_locus_tag="FCN18_10135"
     CDS             complement(7861..8778)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013226.5"
                     /locus_tag="FCN18_RS10135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_10135"
                     /product="UbiA family prenyltransferase"
                     /protein_id="WP_137094618.1"
                     /transl_table=11
                     /translation="MSRLTSPLWRDVVTIHRLEYTLPVAYFCYAALGACFAPAGDGSWP
                     WGPALLAVLANLLLIVGPLALNVAVDSRTDERHQEKRYLAAAASGFGRSRAVRWSLAEL
                     GVGLVLSTTVALWTGSWLVAAAATAIIVLQAAYNLEPVRLKRRGFAGPTAFGIASVGLP
                     FLLSYGAVTSSVDITAWLLASGMGVLAVGRTVWWSLPDRMADAATDISAPAVRYGLRRT
                     VALTCVILAAGLALLVAGLWWRYGPVWAVLGSAAHGVFLACVATLAASTSDTMRPSARR
                     MLKRSLPLVTIAELALVVTALANR"
     gene            complement(8766..10001)
                     /locus_tag="FCN18_RS10140"
                     /old_locus_tag="FCN18_10140"
     CDS             complement(8766..10001)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020420679.1"
                     /locus_tag="FCN18_RS10140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_10140"
                     /product="cytochrome P450"
                     /protein_id="WP_137094620.1"
                     /sec_met_domain="p450 (E-value: 2.8e-38, bitscore: 126.3,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRTELRMALRTLPFLDSHAHRKEGFLELAGGPHPKLLVWHPEAI
                     DWIFRSDAMLEHPGSRSLRPLLGPGSLLWLDGPRHRAYRKLLSAPLSARRVGDYRPIIQ
                     ETIDRALASLTPGTVFTVPEWTRRVTLDIASRILLGSDGLSVLREFTAWLERALGSPHR
                     SLAYRLFRGELPRSGSTLDGELVRRARAACPPALASLVVAPDSPLGTVGDGELRDQIVS
                     LLFAGHETTASATAWTVYWLDRDEVLRGDVLAELNSTTDSGADAKAVPLLHATVQEALR
                     ITPPVLLAGNRMLTEETHLFGRRLPRGAVLSPSVYLAHRGSDSFHRPDRFDPSRFLDGR
                     PLAQHYLPFGGGTRHCLGSQLGLLETRMIVAALLRRRSLRSTRRRAVKARVRGHAMAPS
                     ARLQMKVTACHD"
     gene            complement(10001..11560)
                     /locus_tag="FCN18_RS10145"
                     /old_locus_tag="FCN18_10145"
     CDS             complement(10001..11560)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009152842.1"
                     /locus_tag="FCN18_RS10145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_10145"
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_137094623.1"
                     /sec_met_domain="T2TS (E-value: 2.3e-91, bitscore: 301.5,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSRGSWLANANETVTALVADMAADPWGRFSPSVYETGRIVALTP
                     SLPGHAERVGFLLREQHGDGRWGGPGDYDIVPTLSATHALLTETSRPGAHPEVARAAER
                     GVRALADRLRLNTLLPDTVAIELMVPGLVDDINAHLERLGRPPLTSPKGTYADLLAQLR
                     TAVSQGHPLPEKLLHSLEVVGAPAQSAPFVKPVHGRVVGCSPAATAVWLGDEAVRDERN
                     PCVRYLRAVQEPGGGVPVAAPLALFERSWVLSTLVSAGLDVRVPRELVDGLHAAFSPEG
                     AAGGDGLPPDVDDTATALYALALLGSPRSPESLWHYEADDHFRCFPEERTPSTSANAHV
                     LQAIGASLGLDLPDRERYVAAAKTLTRWLGERQDADGGWHDKWHASPFYATACCATALA
                     EYGGADGNKAVRRAVDWLLATQRKDGSWGRWNGTREETAYAVKTLLHQGVPTTEATVRA
                     AARGAAHLLTTDGDTTHPPLWHDKDLYTPLRIVEVEIIAALYLAHTTAAVAARLTEDRV
                     GV"
     gene            complement(11687..13711)
                     /locus_tag="FCN18_RS10150"
                     /old_locus_tag="FCN18_10150"
     CDS             complement(11687..13711)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009152843.1"
                     /locus_tag="FCN18_RS10150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_10150"
                     /product="neutral/alkaline ceramidase"
                     /protein_id="WP_137094625.1"
                     /transl_table=11
                     /translation="MRARALAAALLTGACLVAAPTTAPAASPAPAEPYLVGRGIADATG
                     EIAEVGMMGYGRTDQQAEGLHNRLRSRAFVVADPATGERVVLVVVDSPMIFDSVHQAVL
                     RRLAERYGDLYTEQNVLLTGTHTHAGPGGYSHHLLYNLTTLGFHEKTFDAITEGIVESV
                     ERAHADLAPASLTLTHSELTDASVNRSRAAFDRNPAEDREFFPAAVDPQTSLLRIERDG
                     RVVGAVNWFATHNTSMSGDNRLISADNKGYAAYHWEREVEHVDYLADTPPDFVSAFAQT
                     NAGDMSPNLDLAPPTTPEDFARTEEIGQRQYEAAARQLTRDGAALTGGVDSRLVYVDMS
                     DVDVRPEFTGDGKHHRTCDPAVGAAMAAGSTEDGPAFPLFAEGENPLWDTVSHSVLYTA
                     SPELRQCQAPKGIAVPIGAMNAVYPWVQETVPVQLVRVGGLYLIGVPGEVTIAAGLRLR
                     RTVADIVGADVRDVLVAGYSNAYFHYVTTPEEYDAQHYEGGSTLFGRWQLPALQQTAAG
                     LAEAMRDGRPAPSGPAPADLSGRRISLQPPIVADAPPLGRRFGDVLTQPRPSYSPGERA
                     EVVFAGAHPGNDLHRGGTYLEVQRWNGNRWIRVADDGDWSTTLRWARRGVAASHVTIGW
                     KVPPGSEGTYRIRYHGEARNLLGGVRSFTGASNQFSVRG"
     gene            complement(13708..14889)
                     /locus_tag="FCN18_RS10155"
                     /old_locus_tag="FCN18_10155"
     CDS             complement(13708..14889)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005452079.1"
                     /locus_tag="FCN18_RS10155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_10155"
                     /product="YncE family protein"
                     /protein_id="WP_113640996.1"
                     /transl_table=11
                     /translation="MAKRWVRLGSLVAAALLAVTLAPAAHAAPARDVMFVGNNWDGTVD
                     LVDARTFEKYQRIDVVPDFEQRKREMTPDRLVAMLVIRQTAGEGHDQLVDDIMVSPDGR
                     TMYVSRPSLGDVSAFDVATGRQLWFTRVDGYRSDHMALSPDGRTLLVSATTANVVNTVD
                     TATGAITGRIASGDFPHENRFSEDGSTIYNATIGNVVAPDAPLLDAAKGRRWLTIADAK
                     TLEVRKVIDFGVGIRPFVVLPDQRTMYAQLSFHNGFIEYDLEEERTTRTVHLPLSEEAK
                     QLRRDEYPLDSAHHGLSTNNDHTKICDAGTISDYAAILSVPALTVDAIVPTGKKPYWAA
                     TSPDGRHCFLSNSDSDDISVVSFDNPREVARIPVGDHPQRVRGYSVPADVLTP"
     gene            14978..15814
                     /locus_tag="FCN18_RS10160"
                     /old_locus_tag="FCN18_10160"
     CDS             14978..15814
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014376.5"
                     /locus_tag="FCN18_RS10160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_10160"
                     /product="AraC family transcriptional regulator"
                     /protein_id="WP_137094627.1"
                     /transl_table=11
                     /translation="MGSGDDARYWRHPGVAGVDLLRARFVRHAFARHSHETFAIGVVES
                     GAEELRIGSAVERVTTGGTVLLNPEVVHTGAPAHADGWTYRVLYLPVAELVSFTGIRGT
                     PAFTEQLTYDRDTAAAVLAAHRAAESPDRLAAGTLLDLLLARLWHAHGSRTPTASPRAG
                     RRDAELVRQVLLERMAGPPPLAELAAEFGTSRFALQRAFRARFGLPPHAYLNQHRVRTA
                     RSLLARGVPPAEVAVTVGFVDQAHLSRHFTRIVGVPPGAYARAHERTSRGRRSRLA"
     gene            15820..17211
                     /locus_tag="FCN18_RS10165"
                     /old_locus_tag="FCN18_10165"
     CDS             15820..17211
                     /NRPS_PKS="Domain: Aminotran_5 (153-300). E-value: 3.4e-11.
                     Score: 34.6. Matches aSDomain:
                     nrpspksdomains_FCN18_RS10165_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1180: Decarboxylase, pyridoxal-dependent"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007025722.1"
                     /locus_tag="FCN18_RS10165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_10165"
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="WP_137094630.1"
                     /sec_met_domain="Aminotran_5 (E-value: 8.7e-09, bitscore:
                     29.3, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDPSREDVAAMMAAATSFVTEFLDGLPHAPASHVTDGDVPALLEP
                     PAERPGELGELLATFRDAAAHAVETAGPGYLAYFPAGGLFSSALAELLANTVNRYTGVS
                     STAPALVAMEQGVLRWLCAEFGLPDGSGGIVTTGASMATLSALVAARERVLGGPLPAGT
                     IYVTEHTHHCVAKAAHLAGFTPEQLRTVPTSDGLRMDPSAAAEAITRDRAEGHVPFLLV
                     GTAGSTSTGTIDPLGALAEVALREGLWFHVDAAYGGGFQLTERGRAKLAGIERADSVTL
                     DPHKTMFLPYGTGVLLVRAVSDLRAAHSADADYLQDLRRDPLLPDYADLGPELTREFRG
                     LRLWLPLHLHGVAAFRSALDEKLDLAAWAHRELSRFAEVPTEPDLTVLTFRVPGGDDAA
                     NRRALERINAGRRIFLSSTRIGGRFTPRLCVLSLRTHRPHVEEAMRIIRDAVVSASRGT
                     PAAAP"
     aSDomain        16279..16719
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FCN18_RS10165_Aminotran_5.1"
                     /evalue="3.40E-11"
                     /label="FCN18_RS10165_Aminotran_5.1"
                     /locus_tag="FCN18_RS10165"
                     /protein_end="300"
                     /protein_start="153"
                     /score="34.6"
                     /tool="antismash"
                     /translation="VLGGPLPAGTIYVTEHTHHCVAKAAHLAGFTPEQLRTVPTSDGLR
                     MDPSAAAEAITRDRAEGHVPFLLVGTAGSTSTGTIDPLGALAEVALREGLWFHVDAAYG
                     GGFQLTERGRAKLAGIERADSVTLDPHKTMFLPYGTGVLLVRA"
     gene            complement(17174..18004)
                     /locus_tag="FCN18_RS10170"
                     /old_locus_tag="FCN18_10170"
     CDS             complement(17174..18004)
                     /NRPS_PKS="Domain: Abhydrolase_1 (25-260). E-value:
                     4.1e-32. Score: 103.6. Matches aSDomain:
                     nrpspksdomains_FCN18_RS10170_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020632264.1"
                     /locus_tag="FCN18_RS10170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_10170"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_113640994.1"
                     /sec_met_domain="PF00561 (E-value: 3.9e-26, bitscore: 86.8,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 3.1e-20, bitscore:
                     68.3, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEYLSIPTPAGSFDALAAGPEDGRPVLLLHGFPEAAVQWEHQVA
                     VLGREGYRAVAPDQRGYSPGVRPEDVAEYAIEHLVGDVVAIADALGWGRFDLVGHDWGG
                     AVAWWTADKHPERLRSITSVATPHPGALADALRRDEDQAMRSQYMRDWRSRDTEKRMLA
                     GNAEALRRMYEWKVPRDRVEDYLRRLSEPGALTAALNWYRAGRPAERIGKVGVPALYVW
                     GTEDVAFGSTAALDTEQWVTGPYEFQMLEDVTHWVPEEVPEAFTALLLEFLGRR"
     aSDomain        complement(17225..17929)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FCN18_RS10170_Abhydrolase_1.1"
                     /evalue="4.10E-32"
                     /label="FCN18_RS10170_Abhydrolase_1.1"
                     /locus_tag="FCN18_RS10170"
                     /protein_end="260"
                     /protein_start="25"
                     /score="103.6"
                     /tool="antismash"
                     /translation="PVLLLHGFPEAAVQWEHQVAVLGREGYRAVAPDQRGYSPGVRPED
                     VAEYAIEHLVGDVVAIADALGWGRFDLVGHDWGGAVAWWTADKHPERLRSITSVATPHP
                     GALADALRRDEDQAMRSQYMRDWRSRDTEKRMLAGNAEALRRMYEWKVPRDRVEDYLRR
                     LSEPGALTAALNWYRAGRPAERIGKVGVPALYVWGTEDVAFGSTAALDTEQWVTGPYEF
                     QMLEDVTHWVPEE"
     gene            complement(18147..19406)
                     /locus_tag="FCN18_RS10175"
                     /old_locus_tag="FCN18_10175"
     CDS             complement(18147..19406)
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016335287.1"
                     /locus_tag="FCN18_RS10175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_10175"
                     /product="cyclopropane-fatty-acyl-phospholipid synthase
                     family protein"
                     /protein_id="WP_112271654.1"
                     /transl_table=11
                     /translation="MAHGELGEVFGRLLTAGEHVAITLYDGSVVGDPGSPHRIDVRSPT
                     ALSYVFSAPGELGLARAYVTGHLDVHGDLYTVLRALTAVIDGLSIADKLWIMRRLGTRF
                     LRSVPVPAEEAPGRVKRGLRGLRHSKSRDSAAISQHYDVSNHFYELVLGPSMAYTCACY
                     PEEDSTLEEAQFHKFDLVCRKLALEPGMRLLDVGCGWGGMVAHAAEHYGVRAIGVTLSR
                     EQAQWGQKNIVARGLADRAEVRHLDYRDVAEGGFDAVSSIGLTEHIGARNLPSYFRFLH
                     SKLREGGRLLNHCITRPTTREPAHTGPFIDRYVFPDGELEGVGTIISAMQDHGFEVRHS
                     ENLREHYARTLAAWCANLDANWSEAVQEAGVRRARVWALYMAASRLGFERHKIELQQVL
                     GVKVAANGDAAMPLRPDWGV"
     misc_feature    19392..19406
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.96"
                     /tool="antismash"
     gene            complement(19415..20794)
                     /locus_tag="FCN18_RS10180"
                     /old_locus_tag="FCN18_10180"
     CDS             complement(19415..20794)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007035464.1"
                     /locus_tag="FCN18_RS10180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_10180"
                     /product="FAD-binding protein"
                     /protein_id="WP_137094632.1"
                     /transl_table=11
                     /translation="MLRSGGGSGSTATAEGYAARVARLREQLAALPEGAPVRLAKRTSN
                     LFRPRADTSSGLDVSDFNHVLSVDPVARTADVEGMVTYEQLVDATLPHGLMPLVVPQLK
                     TITLGGAVTGLGIESSSFRNGMPHESVLEMDLLTGDGEIVLARPENEHSELFFGFPNSY
                     GTLGYALRLRIELEPVRPYVRLEHVRYTDPARYFAALERACREREADFVDGTIFGPDEL
                     YLTLATFTGEAPETSDYTWLDIYYRSIRERTVDHLPVRDYLWRWDTDWFWCSRALGVQN
                     RLVRLLVGPKLLRSDVYWKVVAFERRHGLLSRFERALGKPERESVVQDIEVPVDRAAAF
                     LDFFHREIPISPVWVCPVRQRDPDRTWPLYELDPKALYVNFGFWATVPLEPGEPDGTHN
                     RLIEQKVTELGGRKSLYSESFCDEDTFWRLYNGTAYHALKRRYDPARRLLDLYDKCVRA
                     R"
     misc_feature    complement(20786..20798)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 19.4"
                     /tool="antismash"
     misc_feature    complement(21215..21228)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.41"
                     /tool="antismash"
     misc_feature    21396..21410
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     misc_feature    21529..21544
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.67"
                     /tool="antismash"
ORIGIN
        1 tgatcgtggt gatcctgacg ctgatcgtgg ccacgttcac cctgcgcctg atgttccgga
       61 ccttcgacgt gagcgggggt gtgaaatgag gctcggccgc atctcgctga ccgcgttcac
      121 gtggctggtc gcgatcctgt tcgtctttcc cgtcatctgg atggtgctga cgtcgttcaa
      181 gacggaggcc gacgcctaca ccgatccacc gaggctgttc ttctcgccga ccctggagca
      241 gttcgcgggc gtgttcgaac gcgggttcct gccctacctc gccaactcgg cgttcgtcac
      301 ggtggtgtcg acgctcgccg tgctggtgct ggcgatcccg gccgcctacg cgctttcgat
      361 cgcgccggtc aagggcacga gcaacgtgct cggcttcttc ctgtccacga agatgctgcc
      421 gatcgtggcg gcgatcatcc cgctgtacgt gatctcgcag aacgtgcagc tgctggacaa
      481 cgtgtgggcg ctgaacatcc tctacacggc catgaacctg ccgctggcgg tgtggatgat
      541 gcgctcgttc ttcctcgagg tgccgaagga gatgatcgag gccgcacggg ttgacggcgc
      601 caagctgccg acgctgctct acaaggtcgt gctgcccgtc gtggcgcccg gcatcgcggc
      661 gaccgcgctg atctgcgtga tcttctcgtg gacggagttc ttctacgcag tcaacctcac
      721 cgcagcgcgg gccggcaccg tgccggtgtt cctgtccggc ttcatcacca gtgagggcct
      781 gtactgggcg cagctgtcgg ccgcggccct gctcgcctcg ctgcccgtga tgatcatcgg
      841 ctggatcgcg cagaaccacc tcgtccgcgg cctctccatg ggcgccgtca agtagaggag
      901 cggcgcggcg cggagcggag cggagcgtgg tgcgcgccgg ggtgtgagct gggcgaagtc
      961 cacgtcctcg accccgagac gacgttgtcg atcacccgaa actcccaacc gcagtgacgc
     1021 cgtgtggcgg aacggctacg atgtccagcg tcccgcatat ggtgaggaga gcgagccttc
     1081 aatgtcctcc gacagcgcag cagtcgactc cgagatcgtc gtactggaca acggggtgcc
     1141 gacggccgcc cgcgtctacg acgtcatgct caacggcaag gacaactacg ccatcgaccg
     1201 gcaggtcgcc gaggcgagtc tgtccgtgat gccggagctc aaggagatcg cactgcacaa
     1261 cagggcgatc ctgcaccgcg tggtgcgtca ccttgccgcc gagcagggca tcacgcagtt
     1321 cctcgacctg ggctcggggc tgcccacggc gcgcaacacg cacgaggtgg cccaggaggc
     1381 caaccccgat gcgaaggtcg tctatgtcga catcgacccg atcgtgctgg cgcacggcag
     1441 ggcgctgctg caggacaacg agaacacgcg cgtcgtcacc gccgacctcc gcaagccgga
     1501 ggaggtgctc tcgcaccccg acgtgcagga gatgatcgac ttcagcaagc cggtgtgcgt
     1561 gatgctctgc ggcatcctgc accacctcgc cgacgacgag gacccgaagg gcatcgtgca
     1621 ggccctgcgg gaggccgtgg tgcccggttc gtacttcttc atcacgaact tcacgcggct
     1681 gtcggactcg ccggagagtg aggagctgga gaaggtcctg ctctcgcagc tgggcaccgg
     1741 ccgcgtccgg accccggcgg agctcgagga gttcttcgag ggcctggaga tcctggcgcc
     1801 cggcatcgtg ccgctgccgc tgtggcggcc cgacgagatc gtcaccgacg cgacgacgat
     1861 cggcgtgcgc ttcatgaccg gcggggtcgg caggaagaac tgaggtgctt tccgggacgc
     1921 gggcggcgta accggctgat caccggaaac cgcccgcgcc ccggaatgac ttgacgcgtc
     1981 cctcacctca cgtcgcgcgc ccgctgagct tgtcgcgcat ccggtcgatc aggcccgcgc
     2041 ccgggtcgag gatgcggttg gccggcggct tgtccggcga ctgcgggtgc ggcctcgtcg
     2101 gtgccttctc cttggcccgc aacaccttct cgcccagctc ccgcagctcc tcctcgctgc
     2161 acgccgcgcg cagcttgggc agcagatcgt tctcctcgtc ctcgacgtgg tggcggatcg
     2221 agtccatcag gttgccgagc agctggtcga acttggggtc ggtggcgtcc atgtcctcca
     2281 gctgcttcat cagcagctcg gcctcggagt gctcctcgat ctcgtggtcg gcgagctcgt
     2341 tgccgttctc gaggtgcttg cgcgcggcgg ggtacatgaa ctgctcctcc gcgacggagt
     2401 gccggaccag ctcggcgatg acgtggtcgg cgagctccct gcgacggcgc gggtcggtgg
     2461 ccttgtcctc cagctcggcg aacacccgct cgacctcgcg gtggtcgttc atgatgacgc
     2521 tgatcaggtc gtcggtcatg gggtggctcc tcctgctcgg ttgcctggct ggcggcggag
     2581 tacccgggcc cctgccggcg aaacggctca cgcgcggtgt tcggcgactg tgatcagcac
     2641 cgccttcacg gcggccacgg tgggcaccgc gaacagcaca ccggcgatac cgccctcggt
     2701 gccgccgatc acgagcgcca cgagcaccac ggccgggtgc agcttcgaga ggttgccctg
     2761 cagcaccggt tgcagcacgt gcccctccag ctgctgcacg ccgagcacca cgccgaggat
     2821 gatgagcgcg gccacgccgc cgttgctcac cagggtcacc gcgaccgcga cgaagccgga
     2881 gacgaccgag cccacgtagg gcacgaatcc gccgaggaac accagcgcgg cgagcggaac
     2941 ggtgagcggg acgccgacga tcgcgagccc gatcccgatg ccgatcgcat cgatgagcgc
     3001 gaccagcgct gtcacccaca cgtaggtcac gacgctgcgg taggccctgc ggcccgactc
     3061 gtcgatgacg ttgcgggtcg acgtgcgaaa cggtcgcagc aggaactccc acatcctcgg
     3121 accgtcgtag aggaagatca cgaggagcac agtggacagc agcaggccga tcccgatcgc
     3181 gctcaccgtg ctgaacgcgc cgagcgcctg tgagatcacc gcctgctgat tgccgccgag
     3241 ccactcctgc acccggtcgg acagcccgcc ctcgaactgg aacggtcccc tgcgcagcca
     3301 gtcctcgacc tgggcgatgc tctcggcgac ctgtagccgc agctcgtcga agttgttgag
     3361 gatggaaagc acgacgaagg ccacgaggcc gcccgctacg gtcagccccg cgatcagcga
     3421 ggtcaccacc gcgaggccgc gtggccaccg gtgccggcac aggaagccca ccagcggctg
     3481 caggaacgcc gagagcagca gcgcgatcga catggggatc agcacatagc tcaggtgctc
     3541 gacgacgttg cgcagcgccc acagcgcgag aaagagcagc agcagctcgg ctgacacgat
     3601 ggcagcgctg cgcagcatgc ccgcgctcag ccgcaggcgg ggcttcgaca tgcggtgcgg
     3661 gtatccattc gcgtgcatgc ggaaacagtg gtcgtttgcc gtccgctccg tggggtagcc
     3721 aaggggcccc gaacgcgctg agcgacggcc cgtgtccttg agtgagccca ggagccgacc
     3781 atgttgagcc attacgaacg acaggagctg gaacggatcg cgcaaaggtt cgagcacgac
     3841 gatcccgagc tggccagtgc gctcggttcg tgtgcgcacc cgcgtggcac gctcaggctg
     3901 tcgaagctcg cccgtctcgg tctggacctg ttcgccggtg tgctcgtggt gctgggcgcg
     3961 ctcacgctga acttcgggct ggtgttcgtg ggcgcgctgc tgctgatctg cgccgcgtgc
     4021 gcacacctca agggctggag cccgatcgac ccgccgccca cgcagtaccg ccgcatggag
     4081 tgaccgaggc cagggtgccc agctgcagtg aaggtggcct tcactgcgcc cgcaggacct
     4141 ttcctagccg gtccaggtgt tgccggtgat gcgctcgtag gcctcggtgt agcgcgcccg
     4201 ggtggcctcg acgatctcgg gcggcacctc cggccccggc ggggtgcggt cccagtcggt
     4261 gctcgtggcc cagtcgcgca cgaactgctt gtcgaacgcg tgctgggtcc ggccaggttg
     4321 ccactcgtcg gcaggccaga accgggacga gtcggaggtg agcacctcgt cggccagcgt
     4381 cagcgtgccg tcggcgtccc ggccgaactc cagcttggtg tcggcgacca ggatgccccg
     4441 ggtctcggcg tgcgcggcgc ccctgcggta gatctccagc gtgaggtcgc gcagccgctc
     4501 ggcggtctcc ctgccctctt gccgcactac gtcgtcgaag gtgatgaact cgtcgtggcc
     4561 gacctcggcc ttcgtggtgg gggtgaagat cggctcgggg agctcgctgc cctcctccag
     4621 gcccggcggc agcgcgacgc cggagaccgt gccgtacttc tggtactcct tcagccccag
     4681 cccggcgagg tagccgcggg cgatgcactc gaccttgacc atctccagcg gcttgcaccg
     4741 gatggccctg cgggcgaact cgggcggcac gtcggtgccc gagagcacgt ggttgggcac
     4801 gacgtcgccg aaacgctcga accaccacag cgagagctgg gtgagcagcg cgcccttgcc
     4861 ggggatcggc gtgggcagcg tcacgtcgta caccgagacc cggtcggagg cgaccaggag
     4921 gatgtcgccg ccgtcctcgt agagatccct gaccttgccc gcatggatgt gcttcacgcg
     4981 gctcagcata cgtacgggtt ggaccggcct tgttcgggta gccactggcg gacggtgacg
     5041 gcgagcgagg aggcgacatg gccgagacgg tcggtgacca ggtggtgcgg cgcttgcggg
     5101 agtggggagt cgagcacgtg ttcggctacc cgggcgacgg catcaacggg atcgtcaccg
     5161 ctttcggcaa ggcggacaac cagccgcggt tcgtgcagtc gaggcacgag gagatgtcgg
     5221 cgttccaggc cgtcggctac gccaagttca gcggtgaggt cggcgtgtgc ctcgcgacgt
     5281 cggggccggg cgccatccac ctgctcaacg ggctctacga cgccaagctc gaccacgtgc
     5341 ccgtggtcgc gctcgtgggg cagacggcgc gcaccgcgat gggcggtagc taccagcagg
     5401 aggtggacct gcaggccctc tacaaggacg tcgccgcggc ctacctcgtg gaggtcaacg
     5461 tcgccgagca gctgccgaac gcgctcgacc gggcgttccg caccgcgcgg gcgcggcagg
     5521 cgcccaccgc cgtgatcatc ccggccgacc tgcaggagca ggactacagc ccgccgcagc
     5581 acgcgttcaa gcaggtgccc tccagcccgc ccagctcgcc gcacgcggtg ctggtgccgc
     5641 ccgaggacga gctggcccgc gccgccgagg tgctcaacgc gggggagaag gtggcgatcc
     5701 tcgtcggcca gggcgcacgc aacgccgccg acgaggtcaa gcacgtcgcg gagctgacgg
     5761 gcgccggggt ggcgaaggcg ttgctgggca aggacgttct ccccgacgac ctgccgtatg
     5821 tcaccggctc gatcggcctg ctcggcacgc ggccgacgta cgagctgatg caggagtgcg
     5881 acacgctgct gatcgtcggc tccaacatgc cgtacagcca gttcctgccc gagttcggcc
     5941 aggcgagggc ggtgcagatc gacgtggacg ccagcgtgat cggcatgcgc tacccgaccg
     6001 aggcgaacct cgtcggcgag gcgaagggca cgctgcgcgc gctgatcccc ttgctggagg
     6061 ccaaggacga ccggtcgtgg cggcgggaca tcgagcggaa cgtggccgcg tggtgggaga
     6121 cgatggagca gcaggcgatg ctcgaggcgc ggccggtcaa cccgcagcgg gtggtgcacg
     6181 agctgtccgc gcggatcccc gaggacgcga tcgtcacggc cgactccggc tcgtcgacca
     6241 actggtacgc ccgcaacctg cgcatccgag gccgcatgcg ggcctcgctc tccggcacgc
     6301 tggccacgat gggtcccggc gtgccgtacg cgatcggagc gaagttcgcg cacccggaac
     6361 gtcccgtggt cgcgctcgtc ggcgacggcg cgatgcagat gaacggcatg gcggagctga
     6421 tcaccatcgc caggtaccgc gagctgtggt cggacccgag gctcgtggtg tgcgtgttcc
     6481 acaacgacga cctcaaccag gtcacgtggg agctgcgggc catgggcggc gcgccgaagt
     6541 tcgaggagtc acagtcgctg ccggacgtct cctacgccgg tttcgcgcgc agcctcggtt
     6601 tcgagggcat cgcggtggat gatccgggcg agctcggccc ggcctgggac cgggcactct
     6661 ccgcggacgg tccggtggtg ctggacgtac ggtgcgaccc cgaggtgccg ccgatcccgc
     6721 cgcacgcgac gttcgagcag atgaagtcga cggcggaggc gctgctgaag ggcgacccca
     6781 acgcctggca cgtcctggtg cagggagcca agacgaagat gcaggagttc gtccctggca
     6841 ggcgctgagc gacgcacggt gccgcgctgt agcgcgctgc ttttccttgc ccagcaagcg
     6901 aaaatcaacg ccttggggca gaatgtcgcg gccagcccgg ccaccacaga ggggccgatc
     6961 gcagtagaat ctggtgccct gtgcggcgga agatcacgag gttcggaccg ggccttgccc
     7021 cgaggaggcg tacacagagt ggcactccct gtacctgcga ccgaccagca gaaggctgag
     7081 cagccgagta tcgcccgtgt ccacgactgc tggctggagg gctcgcatca ctccgacctc
     7141 gaccggcaat acgcggacca gatcgcgctc tgcgcaccgc atgtgccgta tctcgtgcgg
     7201 gagtctcgcc agctgctccg ccggatggtc ggctttctcg tcgagcaggg cgtacggcag
     7261 ttcctcgacc tcggaaccgg catccccacc cgcggtcacg tgcacgagat cgcgcaagag
     7321 ctcgacccgt cctgccgggt cgtgtacgtc gacaacgacc cacgcgtcgc agcggacggc
     7381 gcgaaggtgg tcgccgacaa cggcggcgcg gccttcgtac aggccgacat ccggaggccc
     7441 gacgagatct tcggggcgaa ggagtcgcgg gaacttctgg atcggagccg gccggtggcg
     7501 gtgcttctgg tcgaaacgct gctgttcctg cgtgacgagg aggacccggc cgccgtcgtc
     7561 aaggcttacg tcgacgccgt ctgccctggc agctatgtgg gcatcgtgca cttcagtcag
     7621 aacgaggaac tcgaccaggg gctcaacctc ttcagccgca tgttcggtgc tccgccgatc
     7681 gtcacgctcc gggatcgaga tgtgctggtg gacttcttcg ccggtctcga cttggtcgaa
     7741 cccgggatcg ttccggtgcc gctgtggcgg ccggaggacg aggaccccgt cctcaatccg
     7801 gaggcggttc aggtgcacgc cggactcggt cgcaagccct gagcgaaccg gggccggagg
     7861 tcagcggttc gccaaagctg tgacgaccag cgcaagttcg gcgatcgtga ccagaggcag
     7921 actccgtttg agcatgcggc gtgcgctggg ccgcatggtg tcggacgtac tggccgccag
     7981 cgtggccacg caggcgagga acactccgtg tgccgcgctg ccgagtaccg cccagacggg
     8041 tccgtagcgc caccacaacc ccgcgacgag aagcgctaga cccgcagcga ggatcacaca
     8101 ggtcagggcg accgtgcgcc ggagcccgta gcgcacggcc ggcgcggaga tgtccgtcgc
     8161 cgcgtcggcc atgcggtccg gcagcgacca ccacacggtg cggccgactg ccagcacgcc
     8221 catacctgag gcgaggagcc atgccgtgat gtccaccgac gaggtcacgg cgccgtacga
     8281 cagcaggaag ggcagcccga cggacgcgat gccgaacgcc gttgggcctg cgaagccgcg
     8341 ccgcttgagc cggaccggtt cgaggttgta cgcggcctga agcacgatga tcgccgtggc
     8401 cgcggcggcg accaaccacg aaccggtcca cagtgcgacc gtcgtggaca gtacgagccc
     8461 taccccgagt tcggcgagcg accagcgcac cgcacggcta cggccgaatc cagaggctgc
     8521 cgcggccagg taacgcttct cctggtgccg ctcgtccgtg cgcgaatcga cggcgacgtt
     8581 gagggccagc ggccccacga tgagcagcag gttggcgagc acggccagca atgccgggcc
     8641 ccagggccag ctaccgtctc cggccggtgc gaagcaggca cccagcgcgg cgtagcagaa
     8701 gtaggcgacc ggcaaggtgt actcgagccg gtggatcgtc acgacgtcgc gccagagggg
     8761 cgaggtcagt cgtgacacgc cgtcaccttc atctgcagcc gcgctgacgg agccatggcg
     8821 tgcccgcgca ctcgtgcctt taccgcacgg cggcgtgtgc tgcgcaggct ccggcggcgc
     8881 agcagcgcgg cgacgatcat tctggtctcc agcagaccga gctggctgcc caggcagtgc
     8941 cgggttccgc cgccgaaggg caggtaatgc tgcgccaggg gccggccgtc gaggaatcgg
     9001 ctcgggtcga accggtccgg acggtggaat gagtcactcc cgcggtgcgc gagatagaca
     9061 ctgggggaga gcacggcccc ccggggcagt ctgcgaccga acagatgcgt ttcctccgtc
     9121 agcatgcggt tgccggcgag gagcacgggt ggcgtgatgc gcagagcctc ctgcacggtg
     9181 gcgtgcagca gtggcacggc cttggcgtcg gctccactgt ccgttgtgga attcagctcg
     9241 gcgaggacat caccccggag aacctcgtca cgatcgagcc agtacacggt ccatgcggtc
     9301 gccgacgccg tggtctcgtg ccccgcgaac agcaacgaca cgatttggtc ccgtagctcg
     9361 ccgtcgccga ccgtgccgag ggggctgtcc ggtgccacga ccagcgaggc caacgcgggt
     9421 gggcacgccg cgcgggctcg gcgcacgagc tcgccgtcca acgtggatcc cgatcgaggc
     9481 agctcgcccc tgaagagccg gtacgccagc gagcggtggg gcgagccgag agcgcgttcg
     9541 agccacgctg tgaactcccg gagaaccgag aggccatcgg agccgagcag gatccggctc
     9601 gcgatgtcga gggtgacccg gcgcgtccac tcgggcactg tgaagaccgt gcctggagtc
     9661 aaactcgcca atgccctgtc gatggtttcc tggatgattg ggcgatagtc accgaccctg
     9721 cgggcgctca gcggagcgct gagaagtttc cggtaggcgc ggtgtcgcgg gccgtccagc
     9781 cacagcagcg aaccgggtcc gagcaagggc cgcagagagc ggctgcccgg gtgttcgagc
     9841 atggcgtccg agcggaagat ccagtcgatc gcctccgggt gccacaccag gagctttggg
     9901 tgtggtccac ctgccagctc caggaagcct tccttgcggt gcgcgtggga gtcgagaaag
     9961 ggcaatgtgc gcagcgccat gcgcagctcc gtgcggttca tcacacgccg actcggtcct
    10021 cggtaagccg cgccgcgacg gccgcggtcg tgtgtgccag gtagagcgcc gcgatgatct
    10081 ccacctccac gatccgcagc ggtgtgtaca ggtccttgtc atgccacagc ggggggtggg
    10141 tggtgtcgcc gtcggtggtg agcaggtggg cggcgcccct cgccgcggcg cggaccgtgg
    10201 cttcggtggt cgggactcct tggtgcagca gggttttcac cgcgtaggcg gtctcctcgc
    10261 gcgtgccgtt ccagcgtccc cacgagccgt ccttccgctg cgtcgcgagc agccagtcga
    10321 cggcgcggcg cacggccttg ttcccgtcag cgccgccgta ctcggcgagc gccgtcgcgc
    10381 agcacgccgt ggcgtagaac ggagacgcgt gccatttgtc gtgccagccg ccgtcggcgt
    10441 cctgccgctc gcccagccag cgcgtgagcg tcttcgccgc ggcgacgtag cgctcgcggt
    10501 cgggcaggtc gagacccagc gaggcgccaa tcgcttgcag cacgtgggcg ttcgcgctcg
    10561 tcgacggcgt gcgctcctcc gggaagcacc ggaagtggtc gtccgcctcg tagtgccaca
    10621 ggctttccgg cgaccgcggg ctacccagca gggccagcgc gtagagcgcg gtggcggtgt
    10681 cgtcgacgtc gggcggaagc ccgtcgccgc ccgccgctcc ctccggcgag aacgcggcgt
    10741 gcaggccgtc cacgagctcg cgggggaccc ggacgtcgag acccgcggag acgagcgtgg
    10801 acagtaccca ggagcgctcg aagagggcca gcggcgcggc cacgggaacg ccgccgcccg
    10861 gctcctgcac cgcgcgcagg taccgcacgc acgggttccg ctcgtcgcgc accgcctcgt
    10921 ccccgagcca caccgccgtg gcggcggggg agcagccaac gaccctgccg tgcaccggtt
    10981 tcacgaacgg cgcgctctgc gcgggcgcgc cgacgacctc caaggagtgc aacagcttct
    11041 ccggcagcgg atgtccctgc gagacggccg tacgcagctg tgccagcaag tcggcgtagg
    11101 tgcccttcgg cgatgtcagt ggtgggcggc cgaggcgttc gaggtgagcg ttgatgtcgt
    11161 cgacgaggcc gggcaccatc agctcgatcg cgaccgtgtc gggcagaagg gtgttaagac
    11221 gcaaccgatc ggcgagcgca cgtactccac gttcggccgc cctcgcgacc tcggggtgag
    11281 cgccgggtcg ggatgtctcc gtcagcaacg cgtgggtcgc gctcaacgtg ggcacgatgt
    11341 cgtagtcacc gggcccgccc cagcggccgt cgccgtgctg ttcccgcagg aggaacccga
    11401 cccgttccgc gtgtcccgga agggaagggg tgagcgccac gattctgccc gtctcgtaga
    11461 cggacggcga gaaccggccc catggatcgg cggccatgtc ggccaccagc gctgtcaccg
    11521 tctcgttcgc gttcgccagc caggaaccgc gtgaactcat gggcactcct cgacggtcag
    11581 cgcagttgag ttgtcgggcc agccggtaac cggttgaaaa ctcaaagtag catttcgcac
    11641 cgaggtgtca caccgctgtg ctccgaacgg agcagtgtgg tgttggtcaa ccgcggacac
    11701 tgaactggtt ggacgcaccg gtgaaactcc tgactccacc gagcaggttc cgggcctccc
    11761 cgtggtagcg aatccggtac gtgccctcgc tgccaggggg aaccttccag ccgattgtga
    11821 cgtgtgaggc cgcgacgccg cgccgggccc agcgcagggt cgtgctccag tcgccgtcgt
    11881 cggccacccg tatccagcgg tttccgttcc accgctggac ttccaggtag gtgccaccgc
    11941 ggtgcaggtc gttgccggga tgcgcgcccg cgaacaccac ttcggcgcgc tcgccggggg
    12001 agtacgacgg ccggggctgg gtgagcacgt caccgaaccg cctgcccagc ggcggtgcgt
    12061 cggcgacgat gggcggctgc agggaaatcc gccgtcccga gaggtcggcg ggtgcggggc
    12121 cggacggcgc gggcctgccg tcgcgcatcg cctccgcgag ccccgcggcg gtctgctgca
    12181 aagcgggcag ctgccagcgg ccgaacagcg tgctgccgcc ctcgtagtgc tgcgcgtcgt
    12241 actcctccgg cgtggtgacg tagtggaagt aggcgttgct gtaccccgcg acgagcacgt
    12301 cgcgcacgtc ggcgccgacg atgtcggcga cggtcctgcg cagccgcagc ccggccgcga
    12361 tggtgacctc gccgggcacg ccgatcaggt acagcccgcc gacgcgcacc agctgcaccg
    12421 gaaccgtctc ctgcacccac gggtacaccg cgttcatcgc gccgatcggc accgcgatgc
    12481 ccttgggcgc ctggcactgc ctcagctcgg gggatgcggt gtagagcacc gagtgcgaca
    12541 ccgtgtccca caacgggttc tcgccctcgg cgaagagcgg gaaggcgggg ccgtcctcgg
    12601 tgcttcccgc cgccatcgcc gcgccgaccg cgggatcgca cgtgcgatgg tgcttcccgt
    12661 cgccggtgaa ctcgggccgc acgtccacat cggacatgtc gacgtagacc agccgggagt
    12721 cgacgcctcc ggtcagcgcg gcgccgtccc gggtgagctg cctggccgcg gcctcgtact
    12781 gccgctgccc gatctcctcg gtgcgcgcga agtcctccgg cgtggtgggt ggcgcgaggt
    12841 ccaggttcgg cgacatgtca ccggcgttgg tctgcgcgaa cgccgacacg aagtccggcg
    12901 gcgtgtccgc gaggtagtcg acgtgctcga cctcgcgttc ccagtggtag gccgcgtagc
    12961 ccttgttgtc ggcgctgatc agccggttgt cgccggacat gctggtgttg tgcgtggcga
    13021 accagttgac ggcgccgacc acacgcccgt cgcgctcgat gcgcaacagc gacgtctgcg
    13081 ggtcgaccgc ggctggaaag aactccctgt cctcggcggg gttgcggtcg aacgccgcgc
    13141 gggaacggtt cacgctcgcg tcggtgagct cggagtgggt gagcgtgagc gacgcgggcg
    13201 ccaggtcggc gtgcgctcgt tccaccgact ccacgattcc ttcggtgatg gcgtcgaacg
    13261 tcttctcgtg gaagcccagc gtggtgaggt tgtagagcag gtggtgggag tagccgccgg
    13321 ggcccgcgtg ggtgtgcgtg ccggtgagca gaacgttctg ttcggtgtag aggtcgccgt
    13381 agcgctcggc gagcctgcgc agcaccgcct ggtgcacgct gtcgaagatc atcggcgagt
    13441 ccacgaccac gagcaccacg cgctcgccgg tcgcggggtc ggcgaccacg aacgcccgcg
    13501 agcgcagccg gttgtgcagg ccctcggcct gctggtcggt gcggccgtag cccatcatgc
    13561 cgacctcggc gatctcgccg gtggcgtcgg cgatcccgcg cccgacgagg tacggctcgg
    13621 cgggcgcggg ggacgccgcg ggtgcggtcg tgggcgcggc gacgaggcac gcgccggtga
    13681 gcagcgcggc agcgagcgcg cgggccctca cggggtcagc acgtcggcgg gaacggagta
    13741 gccgcgcacg cgctgcgggt ggtcgcccac cgggatacgg gcgacctcgc gggggttgtc
    13801 gaacgacacc accgagatgt cgtcactgtc gctgttggac aggaagcagt gccgtccgtc
    13861 gggcgaggtg gccgcccagt acggcttctt gccggtcggc acgatcgcgt ccacggtcag
    13921 cgcgggcacc gagaggatcg ccgcgtagtc ggagatcgtg ccggcgtcgc agatcttggt
    13981 gtggtcgttg ttcgtcgaaa ggccgtggtg cgcggagtcc agcgggtact cgtcgcgccg
    14041 cagctgtttc gcctcctccg acagcggaag gtgcacggta cgggtggtgc gttcctcctc
    14101 gaggtcgtac tcgatgaacc cgttgtggaa cgacagctgc gcgtacatcg tgcgctgatc
    14161 cggcagcacg acgaacgggc ggatgccgac gccgaagtcg atgaccttgc gcacctcgag
    14221 cgtcttcgcg tcggcgatcg tgagccagcg cctgcccttg gcggcgtcga gcagcggggc
    14281 gtcgggagcg acgacattgc cgatcgtcgc gttgtagatc gtgctgccgt cctcggagaa
    14341 ccggttctcg tgcgggaagt cgccgctcgc gatgcggccg gtgatcgcgc ccgtggcggt
    14401 gtcgacggtg ttgacgacgt tggcggtggt cgccgagacc agcagggtgc gcccgtcggg
    14461 cgagagcgcc atgtggtcgg agcggtagcc gtcgacgcgg gtgaaccaca gctgcctgcc
    14521 ggtggccacg tcgaacgccg acacgtcgcc gaggctgggc cgcgacacgt acatcgtcct
    14581 gccgtcgggg gagaccatga tgtcgtcgac gagctgatcg tggccctcgc ccgcggtctg
    14641 tctgatgacg agcatcgcga cgagccggtc gggcgtcatc tcccgcttgc gctgctcgaa
    14701 gtcgggcacg acgtcgattc gctggtactt ctcgaaggtc cgggcgtcca ccaggtcgac
    14761 ggtgccgtcc cagttgttgc cgacgaacat cacgtcccgt gctggcgcgg cgtgtgccgc
    14821 cggagcgagc gtcacggcca gcagagccgc cgccacgagt gaaccgagcc gtacccaccg
    14881 cttggccata acgtacctac cccgtagtag atatgaaggt gattcacgat tgtgcgggct
    14941 ccggacgacg agcgcaaccc ggacgtaggg tcgcggggtg ggcagtggtg acgacgcacg
    15001 gtactggcgg catcccggcg tggccggagt ggacctgctc cgcgcgcggt tcgtgcggca
    15061 cgccttcgcc cggcacagcc acgagacgtt cgcgatcggc gtcgtcgagt cgggagccga
    15121 ggagctgcgc atcggctcgg ccgtcgagcg ggtcaccacg ggcggcacgg tgctgctcaa
    15181 ccccgaggtc gtgcacaccg gagcgcccgc ccacgccgac ggctggacct accgcgtgct
    15241 gtacctgccg gtggccgagc tggtctcgtt caccggcatc cgcggcacgc cggcgttcac
    15301 ggaacagctc acctacgacc gcgacacggc ggccgccgtg ctcgccgcac accgggccgc
    15361 ggagtcgccg gaccggctcg cggcgggcac cctgctcgac ctgctgctcg cccggctctg
    15421 gcacgcccac ggcagccgga ctcccaccgc ctccccgcga gccggccgcc gggacgccga
    15481 actcgtcagg caggtgctgc tggagcggat ggccggcccg ccgccgttgg cggagctggc
    15541 cgccgagttc ggcaccagcc ggttcgcgct gcagcgcgcg ttccgggccc gtttcgggct
    15601 gccgccgcac gcctacctga accagcaccg tgtccgcacc gcgcggagcc tgctcgcgcg
    15661 cggtgtcccg cccgccgagg tggccgtgac ggtcggcttc gtggaccagg cccacctttc
    15721 ccggcacttc acccggatcg tcggcgtccc gcccggcgcc tacgcgcggg cgcacgaacg
    15781 tacaagcagg gggcgaaggt cccgcctagc gtgaagccca tggatccctc ccgcgaggac
    15841 gtcgccgcga tgatggcggc ggcaacatcg ttcgtcaccg agttccttga cgggctgccg
    15901 cacgcgcccg cgtcccacgt gaccgatggg gacgtgcccg cgttgctgga acctcccgcg
    15961 gagcggccag gcgagctggg cgagttgctc gcgacgttcc gggacgcggc cgcgcacgcg
    16021 gtcgagaccg cgggacccgg ctacctcgcc tacttccccg ccggcggcct gttcagctcc
    16081 gcgctcgccg agctgctcgc gaacaccgtc aaccgctaca ccggcgtcag ctcgacggcg
    16141 cccgcgctcg tggcgatgga acagggcgtg ctgcgctggc tgtgcgcgga gttcggcctc
    16201 cccgatggct ccggcggcat cgtcaccacc ggggcgtcga tggcgaccct gtcggcgctc
    16261 gtcgccgccc gcgagcgggt gctcggcgga cccctgcccg cagggacgat ctacgtcacc
    16321 gagcacaccc accactgcgt cgccaaggcg gcgcacctgg ccgggttcac gcctgaacag
    16381 ctgcgcacgg tgcccacttc ggacgggctg cgcatggacc cctccgccgc agcggaggcg
    16441 atcacgcggg accgcgccga gggccacgtg ccgttcctgc tcgtcggcac cgcggggtcc
    16501 acgagcacgg gcacgatcga cccgctcggc gcgctcgcgg aggtggccct gcgggaaggg
    16561 ctgtggttcc acgtcgacgc cgcatacggc ggcggcttcc agctcaccga gcggggccgc
    16621 gcgaagctcg ccgggatcga aagggccgac tcggtgacgc tcgacccgca caagacgatg
    16681 ttcctgccgt acggcaccgg cgtgctgctc gtgcgtgccg tgagcgacct gcgggccgcg
    16741 cactccgccg acgccgacta cctgcaggac ctgcgccgcg acccgctgct gcccgactac
    16801 gccgacctcg gccccgagct gacgcgcgag ttccgcggcc tgcggctgtg gttgccgctg
    16861 cacctgcacg gcgtcgccgc gttccgctcc gcgctcgacg agaagctcga cctcgcggcg
    16921 tgggcccacc gcgagctgag ccggttcgcc gaggtgccga cggagcccga cctcaccgtg
    16981 ctcaccttcc gggtccccgg cggtgacgac gccgccaacc gccgagcact ggagcgcatc
    17041 aacgcgggga gacggatctt cctgtccagc accaggatcg gtggccggtt cacgccaagg
    17101 ctgtgtgtgc tgagcctgcg cacgcaccgt ccgcacgtcg aggaggcgat gcgcatcatc
    17161 cgcgacgccg tggtcagcgc ctcccgagga actccagcag cagcgccgtg aacgcctcgg
    17221 gcacctcctc gggcacccag tgggtcacgt cctccagcat ctggaactcg tacggccccg
    17281 tgacccactg ctcggtgtcg agcgcggccg tcgagccgaa cgcgacgtcc tcggtgcccc
    17341 acacgtacag cgcgggaacg ccgaccttgc cgatccgttc cgccggcctg cccgcgcggt
    17401 accagttcag cgcggccgtg agcgcgcccg gctcggagag cctgcggagg tagtcctcga
    17461 cccggtccct cggcaccttc cactcgtaca tccgccgcag cgcctcggcg ttgcccgcga
    17521 gcatgcgctt ctcggtgtcg cggctgcgcc agtcgcgcat gtactgcgag cgcatggcct
    17581 ggtcctcgtc gcgccgcagc gcgtcggcga gcgcaccggg atgcggcgtg gccacggagg
    17641 tgatgctgcg caggcgttcg gggtgcttgt cggccgtcca ccacgcgacg gcgccgcccc
    17701 agtcgtgtcc cacgaggtcg aaccggcccc agccgagcgc gtcggcgatc gcgacgacgt
    17761 cgccgacgag gtgctcgatc gcgtattcgg cgacgtcctc cggccgcaca ccgggggagt
    17821 atccgcgctg gtcgggcgcc acggcgcggt agccctcgcg gccgagcacg gccacctggt
    17881 gctcccactg cacagccgcc tcgggaaagc cgtgcagcaa caggaccggt cgcccgtcct
    17941 cgggacccgc ggcgagcgcg tcgaaggaac cggcgggcgt ggggatgctc aggtactcgc
    18001 tcacggaagg agcctagcca gccggattcg gccccctcta tccgcagtga aggccacctt
    18061 cactgcgttg agcgcaggca aggtggcctt cactgcgttg agcgcaggca gggtggcctt
    18121 cactgcggtc gggcggtccc ccgcggtcac acgccccagt cggggcgcag gggcatcgcg
    18181 gcgtcgccgt tcgcggctac cttcacgcca agcacctgct gcagctcgat cttgtgccgc
    18241 tcgaagccca gccgcgacgc tgccatgtac agcgcccaca cccgcgccct gcgcacgcct
    18301 gcctcctgca ccgcctcgga ccagttcgcg tcgaggttgg cgcaccaggc cgcgagcgtg
    18361 cgcgcgtagt gctcgcgcag gttctccgaa tgccgcacct cgaacccgtg gtcctgcatc
    18421 gccgagatga tcgtgcccac gccctccagt tcgccgtcgg ggaacacgta gcggtcgatg
    18481 aacggccccg tgtgcgcggg ctccctggtg gtcggccgcg tgatgcagtg gttcagcagg
    18541 cgcccgcctt cgcgcagttt cgaatgcagg aaccggaagt acgacggcag gttgcgggcc
    18601 ccgatgtgct cggtgagccc gatggaggac accgcgtcga agccgccctc tgccacgtcg
    18661 cggtagtcga ggtgccggac ctcggcccgg tcggcgagac cgcgcgcgac gatgttcttc
    18721 tgcccccact gcgcctgctc gcgcgacagc gtgaccccga tcgcccgcac cccgtagtgc
    18781 tcggcggcgt gcgccaccat gccgccccag ccacagccca cgtcgagcag ccgcatcccc
    18841 ggttccaggg cgagcttgcg gcacaccagg tcgaacttgt ggaactgcgc ctcctccagc
    18901 gtcgagtcct cctcggggta gcacgcacac gtgtaggcca tcgagggacc gagcacgagc
    18961 tcgtagaagt ggttcgacac gtcgtagtgc tgcgagatcg ccgcgctgtc ccgggacttc
    19021 gaatgccgca gcccgcgcag gccgcgcttg accctgccgg gcgcctcctc ggcgggcacg
    19081 ggcaccgaac gcaggaagcg cgtgccgagc ctgcgcatga tccacagctt gtcggcgatg
    19141 ctgagcccgt cgatcacggc ggtcagcgca cgcagcacgg tgtagaggtc gccgtggacg
    19201 tcgaggtgcc cggtgacgta cgcgcgggcg aggccgagct cgcccggtgc ggagaagacg
    19261 tagctgagcg ccgtcggcga gcgcacgtcg atccggtggg gcgagccggg atcgccgacg
    19321 acgctgccgt cgtagagcgt gatggccacg tgctcgcccg cggtgaggag ccgtccgaac
    19381 acctcaccga gttctccatg tgccattgct gctttcacct cgctctaacg cacttgtcgt
    19441 aaaggtctag caacctccgc gcggggtcgt atcgccgttt cagcgcgtga taggccgttc
    19501 cgttgtagag ccgccagaac gtgtcctcgt cgcagaagct ttcggagtac agcgacttcc
    19561 gcccgccgag ctcggtcacc ttctgctcga tgagccggtt gtgcgtgccg tccggctcgc
    19621 ccggctccag cgggaccgtt gcccagaaac cgaagttgac gtagagcgct ttcgggtcca
    19681 gttcgtacag tggccaggtg cggtccgggt cccgctgccg caccgggcac acccacaccg
    19741 ggctgatcgg tatctcgcgg tggaagaagt cgaggaacgc cgccgcccgg tccaccggaa
    19801 cctcgatgtc ctgcaccacg gactcgcgtt ccggtttgcc cagtgcgcgc tcgaaccggg
    19861 agagcaggcc gtgccgccgc tcgaacgcca cgaccttcca gtacacgtcg gagcgcagca
    19921 gcttcggtcc caccagcagg cggacgagcc ggttctgcac ccccagcgcg cgcgagcacc
    19981 agaaccagtc ggtgtcccag cgccacaggt agtcccgcac cgggaggtgg tcgacggtgc
    20041 gctccctgat ggacctgtag tagatgtcca gccacgtgta gtcgctggtc tctggtgcct
    20101 cgccggtgaa cgtcgcgagc gtcaggtaca gctcgtcggg tccgaagatc gtcccgtcga
    20161 cgaagtcggc ctcgcgttcg cgacacgcgc gctccagcgc cgcgaagtac cgcgcgggat
    20221 cggtgtagcg gacgtgttcg agccggacgt agggccgcac cggttccagc tcgatgcgca
    20281 ggcgcagcgc gtagccgagc gtgccgtagg agttggggaa gccgaagaac agctcgctgt
    20341 gctcgttttc gggccgggcg agcacgatct cgccgtcgcc ggtgagcagg tccatctcca
    20401 gcaccgactc gtgcggcatg ccgtttcgga acgacgacga ctcgatgccc agcccggtga
    20461 ccgcgccgcc gagcgtgatg gtcttgagct gcggcacgac cagcggcatc agcccgtgtg
    20521 ggagggtcgc gtccacgagc tgctcgtagg tgaccatgcc ctcgacgtcg gccgtgcgcg
    20581 ccaccggatc caccgacagc acgtggttga aatcggagac gtccagcccg gaggaggtgt
    20641 cggcgcgcgg ccggaagagg ttcgacgtgc gtttcgccag ccgcaccggg gcgccctcgg
    20701 gcagtgcggc gagctgctcc cgcagccgcg ccaccctcgc cgcgtacccc tcagccgtgg
    20761 ccgtgctccc gcttcccccg ccgcttcgca acatgcaacc catgatcgcg ctgtcccggc
    20821 cgcgctgcca gggtccgctg tgggtttgcc tacggtcagg cgaaaacgca ggtcagacgg
    20881 gttgacccaa atggcctatt cgcggtaaga ggcgctgcgc gccgctgtgt tcgtcaacgc
    20941 gggcatggtg gccttcactg cggctgaggt gtcccggcaa cgccgccctc gacggcctcg
    21001 agcgcgtcgt cgtgcccgcg ctcatgcgtc cggacccccg aaaacgccct gaccgaccgt
    21061 cagcacgccc ttcgggtcgt accgcttctt ggcggcctcc agcttctccc actcgtcgcc
    21121 gaagtggtcc ttccagtcct tctccgtcat cggcagcgtg ttggccgggt acaccgtgcc
    21181 gccgagcgcc ttgacccgct cgtacaggcc ggtgttgagc tggatcatcc tcgccacgcc
    21241 cgccgggtcg tacggcttgc ccgtgcgcag cagtgcgaac agccacacga ggtccctcga
    21301 cggcacacgg accagcggtg tcgacagccg ctccctgcgc accgggtaga gcatcacgag
    21361 gcccgagtcg ccgaggtcct cgccgcccgt ctcggcgagc gtgtcggcca ccacggcctc
    21421 cacctcgtca tcgggcacga acacgttgag ccacgggtgc gggtggaacc agctgccctc
    21481 ctcgcgcagc accgcttcgc cgtcggccat ccggtcgagg aactcgtgat aggtcgagtc
    21541 ctccacctcg gcggtctcgc
//
