LOCUS       NZ_SWMS01000004        11440 bp    DNA     linear   CON 10-DEC-2024
DEFINITION  Prauserella endophytica strain CGMCC 4.7182 Scaffold4, whole genome
            shotgun sequence.
ACCESSION   NZ_SWMS01000004
VERSION     NZ_SWMS01000004.1
KEYWORDS    WGS; RefSeq.
SOURCE      Prauserella endophytica
  ORGANISM  Prauserella endophytica
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Prauserella; Prauserella
            coralliicola group.
REFERENCE   1  (bases 1 to 390627)
  AUTHORS   Liu,J.M., Habden,X., Guo,L., Tuo,L., Jiang,Z.K., Liu,S.W., Liu,X.F.,
            Chen,L., Li,R.F., Zhang,Y.Q. and Sun,C.H.
  TITLE     Prauserella endophytica sp. nov., an endophytic actinobacterium
            isolated from Tamarix taklamakanensis
  JOURNAL   Antonie Van Leeuwenhoek 107 (6), 1401-1409 (2015)
   PUBMED   25832628
REFERENCE   2  (bases 1 to 390627)
  AUTHORS   Li,Q.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-APR-2019) Yunnan Institute of Microbiology, Yunnan
            University, No. 2 Cuihu North Rd, Kunming, Yunnan 650091, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 10.16x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_005146945.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 16:32:08
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,852
            CDSs (total)                      :: 7,795
            Genes (coding)                    :: 7,703
            CDSs (with protein)               :: 7,703
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 34 of 92
            Pseudo Genes (incomplete)         :: 69 of 92
            Pseudo Genes (internal stop)      :: 2 of 92
            Pseudo Genes (multiple problems)  :: 13 of 92
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 18:09:25
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 30573
            Orig. end                         :: 42013
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            SWMS01000004.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..11440
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..11440
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..11440
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:6440](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..6440
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     misc_feature    complement(492..508)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 22.03"
                     /tool="antismash"
     gene            complement(1648..2886)
                     /locus_tag="FCN18_RS09325"
                     /old_locus_tag="FCN18_09325"
     CDS             complement(1648..2886)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FCN18_RS09325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FCN18_09325"
                     /product="hypothetical protein"
                     /protein_id="WP_206077848.1"
                     /transl_table=11
                     /translation="MITIFISNRFGSMDTPRLVVADYRAGRVYAVRGAAVNPLGCGVLA
                     EHAGVLSLPERAGRSRGWAFVDDRGGALVVHTGDERRRIPVAIPGEHLACDVTGRYVVI
                     TTGMGANADVWSDVVTIVDVDQDESVRFRTRVGEPGVLVVPDQRDGEPAIVLRHREPGA
                     IEAIPLRDGLGVGSHVPELSGRATTDLAADGHGDAVDHRTGIAATATSRGLERFVIDQG
                     VPRMIGRTPWPVPGRAFYLRFDPATGRAVGVVRGGPTSPGQWTAWTNHLVDVDLSTGHT
                     RSTELPPGLAFRFALGGGRAAVATIHPDGDEVTIVDRSGTDLHRLRTVSLPALSRPPAA
                     GHLPWDPVGDSPAQRRAIALDPTGSMVAVTRGGDSQLHLIGDDGIDTLSVPTPLDEGGH
                     LYWHGGAVDPVGR"
     misc_feature    2863..2876
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.12"
                     /tool="antismash"
     misc_feature    2869..2884
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 23.01"
                     /tool="antismash"
     misc_feature    complement(2869..2887)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.36"
                     /tool="antismash"
     misc_feature    complement(2871..2884)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 16.74"
                     /tool="antismash"
     misc_feature    2871..2885
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 23.65"
                     /tool="antismash"
     misc_feature    2872..2885
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.72"
                     /tool="antismash"
     misc_feature    complement(2872..2887)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.68"
                     /tool="antismash"
     misc_feature    2873..2884
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.79"
                     /tool="antismash"
     misc_feature    complement(2949..2967)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.55"
                     /tool="antismash"
     gene            2966..3064
                     /gene="amiA"
                     /locus_tag="FCN18_RS40515"
     CDS             2966..3064
                     /codon_start=1
                     /gene="amiA"
                     /inference="COORDINATES: protein motif:HMM:NF040714.1"
                     /locus_tag="FCN18_RS40515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="streptamidine family RiPP"
                     /protein_id="WP_245960170.1"
                     /transl_table=11
                     /translation="MDTQIVAEIEEPEQLAHLSATHSNALVENPFD"
     gene            3143..4015
                     /locus_tag="FCN18_RS09330"
                     /old_locus_tag="FCN18_09330"
     CDS             3143..4015
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FCN18_RS09330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FCN18_09330"
                     /product="hypothetical protein"
                     /protein_id="WP_137094494.1"
                     /transl_table=11
                     /translation="MPTESRVAHVPATGAHVLIDSDGAAMVRTSAGRFLRLQAPPPGLW
                     DVLAGDSAGDEATAAYLAALQEEMASREAADAQHRWPASKRTVGLLGSGAVIDELAQAL
                     GEWEVSTQRYATSAQLLATGHPGPDGEPVNGGGGPVACDLVIAYADSGAERADWGRLDV
                     LPGEGVAWLRAYREGENCFVDPIGVTAEDPGSEQVRRRRLAASLVPGQLAAWQRAAPAD
                     GRPIPSSARTFLVGRILAVALAWAQETALLEEYRQTLWTFVPATGTVSEHPVLGYAPPY
                     VPDEPVIRR"
     gene            4051..5004
                     /locus_tag="FCN18_RS09335"
                     /old_locus_tag="FCN18_09335"
     CDS             4051..5004
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014215.5"
                     /locus_tag="FCN18_RS09335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_09335"
                     /product="CocE/NonD family hydrolase"
                     /protein_id="WP_199542597.1"
                     /transl_table=11
                     /translation="MRDGTELRGQFWECTAPAGLVVIRTPYDARQHAATARSWSARGYH
                     CLIQDVRGRYRSGGDWAPYQHEEDDGGQVLAQLGREHPRLPIVLFGASYAAHAALEAAR
                     GAAHAGSGTVAAVIVLVPALGLAETAWDSSGTPQIWHRIGWWHEHGRTRYAQNPLSTAE
                     LARRTAQAGNAGVVDAAKNWGWTPHALAQWQRLWQAERIDLAARYPLDVPLLVISGEDD
                     FFDNDARRLARTWTAASHFVTGPWGHGLAGDIADPELRSRFRAAGGLGGIIEAWLAAHD
                     LPGTAAAWTEPLRCVPHSRSTLDPAEMAWRHERTAP"
     gene            5001..6440
                     /locus_tag="FCN18_RS09340"
                     /old_locus_tag="FCN18_09340"
     CDS             5001..6440
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015100718.1"
                     /locus_tag="FCN18_RS09340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_09340"
                     /product="YcaO-like family protein"
                     /protein_id="WP_113641619.1"
                     /sec_met_domain="YcaO (E-value: 8.2e-46, bitscore: 151.7,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPVDIGRPREHAAGEFPTPAPHRQRVLPVEALVDPVCGVIRSVR
                     QVPHPAGAPTAYLALTAAVSDARRLGEWPADRVSLGTSFGDVEQARIAAVAEGVERYCG
                     NWLPAELPAGELRIATRAQLLDDALTPIPLSALPVFAPWQYDRENFPYERLTEHTPTLW
                     ARCTDEHDADVWVPASLVYLNWRQSRFRQLPRIHHLNYAGIATGQGTQDARDRGVLEII
                     ERDALEVWWHLDGPTIGIDPASVPGLADDLDGSSLTVSLVAMPSEFAPAVAALVHDRDR
                     GLYAAGFSAALDPAQAARKAVLEAVHTWIYTQGCTSADGWVFRAVEQGLLARGLYLDFR
                     EDARYLDAAGQHCEHIIDLGAHVQLWLDPRVHAEARRFAAPAGGIRPITDLPAVTMDEV
                     YQRLRARGHGILTRDLTTSDIRRTSLRVVRTIITGLVPNAPAAFAYLGMSRFEQAALDR
                     GWRTSWDGSPADLTFIPPPHM"
     gene            6615..7562
                     /locus_tag="FCN18_RS09345"
                     /old_locus_tag="FCN18_09345"
     CDS             6615..7562
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FCN18_RS09345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FCN18_09345"
                     /product="hypothetical protein"
                     /protein_id="WP_113641618.1"
                     /transl_table=11
                     /translation="MPVAIPERLRSLFDGLWRSPGYHHLPDGTVTSIRQRPVPSAGAAY
                     PVHTHLVVGSAGLDGLDPGRYLYDHENGHLLRRVAAREPATGWDIERARPATAQTTLVL
                     TVQPGRSFGRYRHRAWPLWIADVAYAQTAVEFLITQHLKTSTGPGPLLRALLGVPRAAC
                     AQPWLSRGLVPEIPLAAVELPPSWTVDADRSHALATRRSPALSEFEQATGRRPEPRAVE
                     VARLSGQGWVLGADRVETWSVPAQAPAQDIAGAVWQAHRRAASLCYDGTLSGRWRSRPI
                     SGIAAGHGRWITHALAMLPASGHRHTNDAQEACA"
     gene            7559..9214
                     /locus_tag="FCN18_RS09350"
                     /old_locus_tag="FCN18_09350"
     CDS             7559..9214
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.5"
                     /locus_tag="FCN18_RS09350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_09350"
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="WP_113641617.1"
                     /transl_table=11
                     /translation="MMIVRELWREAARFPAALAWSIALLVLVFATHVGQAVAIAWSMSA
                     VLDGQAQDVLVALGAIVGIALARLVLSLVQTSAAARLGGQVRKTIRRRAMRAALVPDRL
                     HDTTVRDGSMRASLGDGIDGTDAYVSKYIPVIAQLFVTCPLVIIAVMVLSPWAGLCVAA
                     GVVLALAGPMAWKRMMARRGLDHWGSYEAVSADLLESLRGMSTLRTLGDVSGTRRRLHA
                     RSEALRRATERVMRVSLAETGVTDFAIQAGVVAAAGAAIVHAVTGQPPAVEVYLILLLV
                     SEAFRPIRELSRHWHAGFLGLTAIPGLARIGAFAGAADTAQPTPAAGAGGAVSPEQARQ
                     LRVRALSFRYADSDGPVLDGLDLTARRGTLSAIVGPSGAGKSTLFDLLLGFLTPDAGTI
                     DLDGRPLRGDDIAVVSQRPVLFAGTIRDNLAVTGTVAESELIAACRAAGILEEIQAFPR
                     GFDTEVTEAGSSLSGGQRQRLALARALLAHRPVLLVDEPTSALDPVRAADVIETLHRVA
                     AERIVIMISHRPETLTGVDNVLRLNSGQLDRSTR"
     gene            9211..10986
                     /locus_tag="FCN18_RS09355"
                     /old_locus_tag="FCN18_09355"
     CDS             9211..10986
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.5"
                     /locus_tag="FCN18_RS09355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FCN18_09355"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_113641616.1"
                     /transl_table=11
                     /translation="MTTIPSPRTFRALLPVLRPEWRGMLGSYLIGTASAMALAALSVLT
                     AWAVGHAVVERALPGLGWWIVLTGLVVVRTVLTWREMDVSHALAYRVLARLRMALFDAY
                     ARSVPGRRREHSGHAASVAMDDIEKLEFFYAHTIAQLGASITVFLTCLATAFALLPEAG
                     IVLLAGSVLVATSAFYGAGAIRRLGAAEQHERSSLSVRIVDALGALREVLAYGLTSRII
                     ADTIDATTRITTIARRRELLTQLVTAIREFIVTAVVIGVIATSAFAAGVLSGTAEPRLS
                     PALLPALVALALAGVLATTDATTTLTQLHPLVASAQRVADGINRPPVVTAPTSPRPLPD
                     GPLGLRFRDVSFSYDDRPPTLSSWSADIAAGEHVGLTGPSGSGKSTLIALAARLWDPSS
                     GSIELVDRDGATLPINQIDDTALRGAVALVDQDATLFHGTVRDNLLRGTTPLPDDELTV
                     ILRRVGTAESIGLDDDLGQSGLRLSGGQQARLCLARALVRQPRILLVDEVTASLDPDTE
                     HAISNVIADFTGTALIASHRAETLSRLDRSIDIGAGHTHHATTDAAATRDHDPPDPKKP
                     GPERSPGPSPSAMPH"
     misc_feature    10561..10563
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
ORIGIN
        1 ggttcggtcg gcacgccaca cggcggcgtc gccgcccctg tcccgcaggg cgtcgacgac
       61 cgcttgggtg gcatcggcgt tgacgcggga gtcgtccgcg agcactacgc cgaggaatct
      121 cggaagccgg atcccggcag gcagagtttg ggcgcggtgc aacggtgaga tgcggcgcag
      181 ttcgtcgatg cctccggggc tgtccggatc gccgaactcg ttgatccagt ggtgcccgag
      241 cggatgggcg tcgaggttga gcaggtcgag cggtgccgcg gtgctgacga ccccggcgca
      301 caggtccggg aagccgagtg cgcaactgga taccagcact ccgccgtggg aagcgccgac
      361 cagtacgagc tggtcggggc gggtgtagcc ggcctcgacg aggccgcggg cgacgcaggc
      421 aaggtcgtcg ataccgcggt gtttgttcct cccgcggccg gcatcgcgcc aggccctgcc
      481 gcgctcgccg ccgccccgaa cgtgtgcgat ggcgtaccgg ccaccgtgtt cgatccaggc
      541 ggggatggtc ggttcgaaca ccgggaggct cggcaccccg aatccgccgt agcaggtcag
      601 gatcagcgga gtcggcccgt cgatgtcgac gggagaggtg atcgccaccg atatgttctc
      661 gccgtcgtcg gcggtgaccg tgtgccattg ggtgcgggcg accgtggcgt tctcgcggct
      721 gctggtctcg gcggtgtccg cgagcagctc gagggctggg acgacgcgtg ggggcagggc
      781 cggcgcttcg atgagaacgt gaacccggcc gtcgtcggca ctcaccccgc tcgccacggc
      841 cggagctcct cggtagctga cgaggcgctc gtcgatgacg tgtccgtcgg cgagccggaa
      901 gaggacgctg tggccgtccc ggacggcgcc aatgtgcacg tgccggcctg cgaccgcgag
      961 ggacgtgatc tgcagggcag gatcctgcca ggaccatttc tcggtcccgc cgcgagggtc
     1021 gaggacatga agcgtggtgc cgtcgtcgat gaggacgtcg tcgccgatgc cgacgacccg
     1081 gacgactgcc gggaacgagg cgaagtgtct gccggtggca cggtcgacca tgcgggtggg
     1141 tgtgcccggt cggctttcgc agaggagccc gcgcgggcct gccgggaaca accgcacgcg
     1201 cgcctcagcg gtcagttccg tggtcgtgac ccgctgggcg gtcacatcga cgctgacgag
     1261 gcgttggggt tctcgggcga cgaggtcgac cgtgcgcgag tgcgcgtccc acaccatggg
     1321 ctcgtagcga cagcggatac ccggatacgg gtggacctga ccggatgcga cgtccacgat
     1381 cgccaggtcc gcgttctcgt cggcgtgctc ggcgagctgg atcgcgatgt ggcggcgatc
     1441 cggggccgcg gccatgcgca gaatgtgccc gtccggttcg atgacggcct caccggtgtc
     1501 ggcgcgatag atgccgcgac gctgccgccc gggtaggcgg ctgagtgtga aaccgctgtc
     1561 gggcaggcca ggccggccgt gccgctccca gcgggacaag gcggcatcca gcgcagggtc
     1621 gatcgggacg atcacctcag tcacggttca tcgaccgacc gggtcgacgg cgccgccgtg
     1681 ccagtacagg tgcccgccct cgtcgagtgg tgtgggcacg ctgagggtgt cgattccgtc
     1741 gtcgccgatc aggtgcagct gactgtctcc gccgcgggtg acggccacca tcgaaccggt
     1801 ggggtcgagg gcgatcgccc tgcgctgggc cggggagtcg ccgaccggat cccacgggag
     1861 gtgtccggcg gccggtggac gggacagtgc tggcagtgaa accgtgcgga ggcggtgcag
     1921 atccgtgccg gagcggtcga cgatcgtcac ttcgtcgccg tcgggatgga tcgtggccac
     1981 cgctgcccgc cctccgccga gcgcgaaccg gaacgccagc cccgggggga gttccgtact
     2041 gcgcgtgtgg ccggtggaga gatcgacgtc cacgagatgg ttcgtccagg cggtccactg
     2101 accaggggag gtgggaccgc cgcggacgac gccgaccgct cggcccgtgg ctggatcgaa
     2161 gcgcaggtag aacgctcgcc ccggaaccgg ccacggggtg cggccgatca tgcggggcac
     2221 accctgatcg atgacgaacc gttccaggcc tcggctggtt gccgtcgccg cgatccccgt
     2281 ccggtgatcg acggcatcac catgcccgtc agcggcgagg tccgttgtgg cccgcccact
     2341 cagttctggc acgtgcgaac ctacgccgag gccgtcgcgg agcgggatcg cttcgatggc
     2401 tccgggttct cggtgccgta gcacgatcgc cggttcgccg tcgcgctggt cgggcacgac
     2461 aaggacgccg ggttcgccga cacgggtacg aaagcgcacc gactcgtcct gatcgacatc
     2521 gacgatggtg acgacatcgc tccacacgtc cgcgttcgcg cccatccctg tcgtgatcac
     2581 gacgtaccgg ccggtgacat cgcaggcgag atgttcgccg gggatcgcga ccgggatccg
     2641 cctgcgctcg tcgcccgtgt gcaccacgag cgcgccgccg cggtcgtcga cgaaagccca
     2701 cccgcgagac cggcccgccc gttcgggcaa cgacaacaca cccgcgtgtt cggccagcac
     2761 gccgcagccg agcgggttca cggcagcgcc gcgaacggcg tacacgcgcc ctgcccggta
     2821 gtcggcgacc acgagccgcg gagtatccat gctcccaaac ctattagata tgaaaatcgt
     2881 tatcaactag ggtcgacggt gttcgcctcg cgaactcgtg tcggccttcc cgccggcacg
     2941 gcccatccat cgagaggagt ccgcaatgga cacgcagatc gttgctgaga tcgaggagcc
     3001 cgagcagctg gcgcacctgt cggccacgca ctcgaacgct ctcgtcgaga acccgttcga
     3061 ctgaccacgt cgccagcgag tacacactcc cggtcgggca gcccttcggg gttgcccgac
     3121 cgggcccttc gaaaggccgc cgatgcccac cgaatctcgt gtcgctcacg tgcccgccac
     3181 cggcgcgcac gtgctgatcg actccgacgg cgccgcgatg gtgcgcacgt ccgcgggccg
     3241 gttcctgcgc ctgcaggcgc cgccgccggg gctgtgggac gtcctcgccg gggactcggc
     3301 cggtgacgag gcgaccgcgg cctacctcgc cgcgctccag gaggagatgg cctcacgtga
     3361 agccgccgac gctcagcacc ggtggccggc ctccaagcgc acggtgggac tgctcggatc
     3421 cggtgccgtc atcgacgagt tggcccaggc actgggtgaa tgggaggtga gcacacagcg
     3481 gtacgccacg agcgcgcaat tgctggcgac tgggcacccg gggccggacg gtgaaccggt
     3541 gaacggtggg ggcgggcccg tagcgtgcga tctggtgatc gcctatgcgg actctggtgc
     3601 ggagcgggcc gactggggcc ggctggatgt cctgccgggc gagggggtgg cgtggctgcg
     3661 cgcctatcgg gaaggcgaga actgtttcgt cgatccgatc ggcgtgaccg ctgaggaccc
     3721 gggaagcgag caggtgcggc gccggcgttt ggcggccagc ctcgtgcccg gacagttggc
     3781 cgcctggcag cgggcggccc ccgccgacgg caggccgata ccgtccagcg cgcgcacctt
     3841 cctggtcggc cgcatcctcg ccgttgcctt ggcgtgggcg caggagaccg cgctgctgga
     3901 ggagtaccgg cagacgctgt ggacgttcgt accggcgacc ggcacggtca gcgaacaccc
     3961 tgtcctgggc tacgccccgc cgtatgtgcc cgatgagccg gtgatccgac ggtgatgaca
     4021 cccgtgcagc cacgcgagca tgtgtgccgc atgcgcgacg gcaccgagct tcgagggcag
     4081 ttctgggagt gcacggcccc ggccggcttg gtcgtgatcc gaacccccta cgacgcgcgg
     4141 cagcacgcgg cgacggcgag atcctggtcg gcgcgcggct accactgcct gatccaggac
     4201 gtccgcggac ggtaccggtc cggcggcgac tgggccccct accagcacga ggaggacgat
     4261 gggggccagg tgctcgccca gctgggccgc gagcaccctc gactgccgat cgtgctgttc
     4321 ggcgcgtcct atgccgcgca cgcggccctg gaagccgctc gcggcgcggc acacgccggc
     4381 agcggcaccg tcgcggcggt gatcgtgctc gtcccggcgc tgggactcgc cgagaccgcg
     4441 tgggacagct caggtactcc gcagatctgg catcgaatcg gatggtggca cgaacacggc
     4501 cgcacccgct acgcccagaa cccgctgtcc acggccgaac tcgccaggcg cacagcgcaa
     4561 gccggcaacg ccggtgttgt cgatgccgcg aagaactggg gctggacacc acacgcgcta
     4621 gcacaatggc agcggctttg gcaggccgaa cggatcgacc tggccgcacg ctaccccctc
     4681 gatgtcccgc tgctggtgat cagcggcgag gacgacttct tcgacaacga cgcccgtcgc
     4741 ctagcgcgca cctggaccgc ggcgagtcac ttcgtcaccg ggccctgggg acacgggctg
     4801 gccggagaca tcgccgaccc cgagctgcgg agccgtttcc gcgccgccgg cggcctgggc
     4861 ggcatcatcg aggcgtggct ggcggcccac gacctgcccg gcaccgcggc ggcgtggacc
     4921 gagcccctgc ggtgcgtgcc tcactctcgc tcgacgctcg atcccgccga gatggcgtgg
     4981 cgtcacgaaa ggaccgcacc atgacccccg tcgacatcgg ccgaccgcgt gagcacgccg
     5041 cgggtgagtt cccgacgcca gcaccgcacc gccagcgcgt gctgcccgtc gaggcgctgg
     5101 tagacccggt gtgcggcgtc atccgctctg tccgccaggt gccacacccc gccggtgcgc
     5161 ccaccgccta cctcgccttg accgcggccg tctcggacgc ccgccggctg ggcgaatggc
     5221 cggctgaccg cgtgtccttg ggcacctcct tcggcgacgt ggaacaggcc cgcatcgcgg
     5281 cagtcgccga aggcgtcgaa cggtactgcg gcaactggct ccccgccgag cttcccgccg
     5341 gggaactacg catcgcgacc agggcccagc tgctcgacga tgcgctcact cccatcccac
     5401 tgagtgcgct gccggtgttc gccccgtggc aatacgaccg ggagaacttc ccctacgagc
     5461 gactcaccga gcacacgccc acactgtggg cccgctgcac cgacgagcac gacgcagacg
     5521 tgtgggtccc tgcctcactg gtctacctga actggcggca atcccgattc cggcagctgc
     5581 cccgcatcca tcacctcaac tacgcgggca tcgccaccgg acaaggcacg caggacgccc
     5641 gcgaccgcgg cgtactggag atcatcgaac gcgacgcgct cgaagtgtgg tggcacctcg
     5701 atggacccac gatcggcatc gaccccgcca gtgtgcccgg cctcgcggac gatctcgacg
     5761 gcagcagcct gaccgtgtcg ctggtggcca tgccctcgga gttcgctccc gccgtagccg
     5821 ctctcgtgca cgatcgggac cgtggcttgt acgcggcggg attctccgcc gccctcgacc
     5881 cggcacaagc cgcccgcaaa gccgtcctgg aagccgtgca cacctggatc tacacccaag
     5941 gctgcacgag cgccgacggg tgggtgttcc gtgccgtcga acagggtctg ctggcccggg
     6001 gcctgtacct cgatttccgc gaggacgcac gttatctcga cgccgcgggt cagcactgcg
     6061 agcacatcat cgacctcggc gcgcatgtcc aactctggct cgatccccgc gtccacgccg
     6121 aggcgcgccg gtttgccgct ccggccggcg ggatacgccc gatcaccgac ctgccggcgg
     6181 tgaccatgga cgaggtctac caacgtctgc gcgcacgcgg acatggcatc ctcacccgag
     6241 acctgaccac cagcgacatc cgccgcacct cgttgcgcgt cgtccggacc atcatcaccg
     6301 gtcttgtccc caacgcgccg gcagccttcg cctacctcgg catgtcccgc ttcgagcagg
     6361 ccgccctcga ccggggatgg cgcacctcat gggatggcag cccggcagac ctcaccttca
     6421 ttccgccccc gcatatgtag gccccgccaa tgacccccgt gaccacaggc acccccacag
     6481 acagcaccca gcggcatgcg gcaccggcga tgtggagtct cccggcgccc ctggcacgcg
     6541 ccctcactcc ggagagtccc gggccaccgg tggcacccgg accccgggtc aacccatggc
     6601 agggggccgg agcggtgccc gtcgccatcc ctgagcgtct gcggagcctg ttcgatggtt
     6661 tgtggcgcag ccccggttac caccacctgc ccgacggtac cgtcaccagc atccggcaac
     6721 ggccggtgcc gtcggccgga gccgcctacc cggtgcacac ccatctcgtc gtcggcagcg
     6781 cgggcctcga cggtctggac ccaggccgct acctctacga ccacgagaac gggcatctcc
     6841 tgcgccgggt cgcggcccgc gaacctgcca ccggatggga catcgagcgc gcccggcccg
     6901 ccaccgcgca gaccacactg gtgctgaccg tacagcccgg ccgcagtttc ggacggtatc
     6961 gccaccgcgc gtggccgctc tggatcgccg atgtcgccta tgcgcagacg gcggtggagt
     7021 ttctcatcac ccagcacctg aagacctcga ccggtcctgg gccgctgctg cgggcactgc
     7081 tcggtgttcc gcgcgcggcc tgcgctcagc cgtggctgag ccgagggctc gttcccgaga
     7141 tcccgctggc ggcggtcgaa cttcctccat cgtggacagt cgacgccgac cgcagccatg
     7201 cgttggccac ccggcgctct ccggcgctca gcgagttcga acaggccacc ggccgtcgcc
     7261 ctgagccgcg tgccgtggag gtcgcgcgcc tgtccgggca gggctgggtt ctcggggcgg
     7321 accgggtcga gacgtggtcg gtgcccgcgc aggccccggc tcaggacatc gccggggccg
     7381 tgtggcaggc gcatcgtcgc gccgcgtcac tgtgctacga cggaacgctg tcgggccggt
     7441 ggcggagccg gccgatctcc ggaatcgccg ccggccatgg gcgctggatc acacatgccc
     7501 tcgcgatgct gccggcgtcc gggcaccgtc acacgaacga tgcccaggag gcctgcgcat
     7561 gatgatcgtg cgcgagctgt ggcgcgaagc ggcccggttc cctgccgcac tggcgtggag
     7621 catcgcccta ctggtgctcg tcttcgccac ccatgtcggc caggctgtgg cgatcgcgtg
     7681 gtccatgtcg gcggtcctgg acgggcaggc gcaggacgtg ctcgtggcgc tgggagccat
     7741 cgtcgggatc gcgctggccc gcctggtgct ctcgctggtt caaacctcgg cggcggcgcg
     7801 gctgggcgga caggtgcgga aaacgatccg ccgccgggcg atgcgggccg cgctggttcc
     7861 cgaccgcctg cacgacacga ccgtccggga cggatcgatg cgggcaagcc tcggcgatgg
     7921 gatcgatggc accgacgcgt acgtatcgaa gtacatcccg gtcatcgctc agctcttcgt
     7981 cacctgtcca ctggtgatca tcgccgtgat ggtgctgtca ccatgggcgg gcctgtgcgt
     8041 ggctgccggg gtcgtgctcg ccctggccgg gccgatggcg tggaagcgga tgatggcccg
     8101 gcgcggactc gatcattggg gcagctacga agctgtcagc gccgacctgc tcgaatccct
     8161 gcggggcatg tccacactac gcacgcttgg ggacgtctcc ggcacccgac ggcgcttgca
     8221 cgcacgctcc gaagcattgc gacgagccac cgaacgagtc atgcgggtgt cgctggccga
     8281 gacgggggtg acggacttcg cgatccaagc cggagtcgtc gccgcagcgg gcgccgcgat
     8341 cgtccacgcc gtcaccgggc aaccgcctgc cgtcgaggtc tacctgatct tgttgctcgt
     8401 ctccgaagcg ttccgtccga tccgggagct ctcccgccac tggcatgcgg ggttcctcgg
     8461 gctgaccgcg atccccggcc tggccaggat cggtgccttc gccggggcgg cagacacggc
     8521 acagcccacc ccggcggcgg gtgcgggcgg cgcggtctca cccgagcagg ccaggcagtt
     8581 gcgggtgagg gcgctgagct tccgttacgc cgactcggac ggcccggtac tcgacggtct
     8641 cgatctgacc gcgcgcaggg gcacgctgag cgccatcgtc ggcccctcgg gggcaggtaa
     8701 atcgaccctg ttcgacctcc tactcgggtt tctcaccccg gatgccggaa cgatcgacct
     8761 ggacgggcgg ccactgcggg gcgatgacat cgcggtggtt tcccaacggc cggtgctctt
     8821 cgccgggacc atccgcgaca acctcgccgt caccgggacc gtagcggaat ccgagctcat
     8881 cgctgcctgc cgtgccgccg gcatcctcga ggagatccag gcgtttcccc gcggcttcga
     8941 caccgaggtc accgaagcag ggtcgagcct gtccggcggg caacgccaac gactcgccct
     9001 ggcccgcgcg ctgctggcgc accggccggt tttgctcgtg gacgaaccga cgagcgccct
     9061 ggatcccgtc cgcgccgccg acgtgatcga gacactgcac cgggtcgccg ccgagcgcat
     9121 cgtgatcatg atcagccacc gacccgaaac actcaccggg gtggacaacg tgctgcggct
     9181 gaactccggt cagctggaca ggagcacccg gtgaccacga tcccttcacc gcgcaccttc
     9241 cgtgcgctgc tgccggtgct ccgccccgaa tggcggggca tgctcgggag ctatctcatc
     9301 ggcaccgcca gtgccatggc gctggcggcc ttgtcggtcc tgaccgcgtg ggccgtaggt
     9361 cacgcggtcg tcgagcgcgc cctgcccggg ttgggatggt ggatcgtact gaccggcctc
     9421 gtcgtggtgc ggacagtgct gacctggcgg gaaatggatg tctcccacgc cctggcctac
     9481 cgcgtgctgg cacgactgcg gatggcgctc ttcgacgcct acgcacgcag tgtcccaggc
     9541 cggcgccgtg agcattccgg acatgccgcg agtgtggcga tggacgacat cgagaagctg
     9601 gagttcttct acgcccacac gatcgcccaa ctcggggcct ccatcaccgt gttcctcacc
     9661 tgcctggcca ccgcgttcgc actactgccc gaagcgggca tcgtcctgct cgcgggtagc
     9721 gtcctcgtcg ccaccagcgc gttctacgga gccggagcca tccggcggct gggcgcggcc
     9781 gaacaacacg aacgctcctc attgtcagta cggatcgtcg acgcgctcgg cgccctgcgt
     9841 gaagttctgg cctacggtct cacctcgcgc atcatcgccg acaccatcga cgccaccacc
     9901 cggatcacca cgatcgcccg gcgacgcgaa ctgctgacgc aactggtcac cgccattcgc
     9961 gagttcatcg tcaccgctgt cgtcatcggc gtgatcgcta ccagcgcttt cgccgccggg
    10021 gtgctctccg gcactgccga gccgcgactg tccccggcgc tgctgccagc cctggtcgcg
    10081 ctcgccctcg cgggagtcct cgccaccacc gacgcgacga ccaccctcac ccagctgcac
    10141 ccactggtgg ccagtgccca gcgtgtcgct gacggcatca accggccccc ggtcgtcacc
    10201 gcgccgacct cgccgcggcc gctccccgac gggccgctgg gcctgcggtt ccgtgacgtg
    10261 tccttctcct acgacgaccg gccaccaaca ctgtcgtcct ggtcagcgga catcgctgcc
    10321 ggcgagcacg tgggcttgac cggaccctcg ggttccggca agagcaccct catcgccctc
    10381 gccgcacgac tgtgggaccc gtcgtcgggc agcatcgaac tcgtcgaccg cgacggcgcg
    10441 accctgccga tcaaccagat cgacgacaca gccctccgag gggcggtcgc cctggttgat
    10501 caggacgcaa ccttgttcca cggcaccgtc cgcgacaatc tcctccgcgg caccacgccg
    10561 ttacccgacg acgagctgac agtgatactc cgccgggtag gtaccgccga gtcgataggt
    10621 ctcgacgacg acctcggcca aagcgggctc cggctctccg gcggacagca agcccgcctc
    10681 tgcctcgccc gcgccctcgt ccgccagccc cggatcctgc tcgtggacga ggtcactgcc
    10741 agcctcgacc ccgacaccga acacgcgatc tcaaacgtca tcgccgactt caccggcacc
    10801 gccctcatcg cctcgcaccg tgccgagacc ctcagcagac tcgaccgcag catcgacatc
    10861 ggcgccggac acacccacca cgccaccact gatgccgcag ccaccaggga ccatgaccca
    10921 ccggatccca agaagccagg acccgaaagg tccccggggc cgtcaccgtc ggccatgccg
    10981 cactgagtgg gtcgatggcc gcgggccgcg cggccgttgc ccggctacgg tgccctcatc
    11041 gtgttggtga gttccggcat gtcggcggtc ttctccggac aacgacgcga ggacggcttc
    11101 ttgcgccgtc tccggcagcg tatggagcag ctgcatgacg cggtccagtc gtctgcggcc
    11161 accagcacgg tcgggcaggc ccggagtggg tcgcatctgt ggtggtacac cggtgacctc
    11221 ctcgacacca cccgagccgt gaccggcttc gaacagcgcc ttctcggcgg ccagggtcgc
    11281 actgtccttt tcctcggaca tgccgatcgg cccgtccatc cgtccgttga ggaactgcct
    11341 caccaccggc tcctcggatg tcaggagcag ttccctcggc ccgaacatga ccagctcctt
    11401 gcggaagagc atgccgatgt tgtccggcac cgtccgggcg
//
