LOCUS       NZ_CP039292            27813 bp    DNA     circular CON 28-MAR-2024
DEFINITION  Actinomyces procaprae strain dk561 chromosome, complete genome.
ACCESSION   NZ_CP039292
VERSION     NZ_CP039292.1
KEYWORDS    RefSeq.
SOURCE      Actinomyces procaprae
  ORGANISM  Actinomyces procaprae
            Bacteria; Actinomycetota; Actinomycetes; Actinomycetales;
            Actinomycetaceae; Actinomyces.
REFERENCE   1  (bases 1 to 3600355)
  AUTHORS   Dong,K.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-APR-2019) National Institute for Communicable Disease
            Control and Prevention, Chinese Center for Disease Control and
            Prevention, Changping District Changbai Road, No. 155, Beijing
            102206, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 278.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004798665.1-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 04:44:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,013
            CDSs (total)                      :: 2,952
            Genes (coding)                    :: 2,897
            CDSs (with protein)               :: 2,897
            Genes (RNA)                       :: 61
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 24 of 55
            Pseudo Genes (incomplete)         :: 35 of 55
            Pseudo Genes (internal stop)      :: 2 of 55
            Pseudo Genes (multiple problems)  :: 5 of 55
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 15:51:19
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 70302
            Orig. end                         :: 98115
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP039292.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..27813
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..27813
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..27813
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:17813](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..17813
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            complement(355..1593)
                     /locus_tag="E4J16_RS00305"
     CDS             complement(355..1593)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008732379.1"
                     /locus_tag="E4J16_RS00305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="histidine kinase"
                     /protein_id="WP_240038192.1"
                     /transl_table=11
                     /translation="MTVLGDAIASLAARARSVLLRQPEPLSRRRIYVFIGAIVGIGNLV
                     FNLAANLQAVKPLDLAFMTVALVSVTVIPVRPVPGVLAYLTCWVLLLLIPAADFSDMTI
                     SNLAFLFFLGRFFPPWPAFSVLLATLLVEAVLLVSLSSPGNAIGNTLGTLWYTALMGAL
                     LVPLGALMRFVEASRLAEAEQADAQLEEMRLEIAREMHDLVAYSMSQTALRAQRAAADT
                     SYPDRARSEFTALEATASDALHELRLLLRTLRTPSSEQEKSISATTGLGNAVTDLRTAV
                     GAISADVSSAGFDITYRHLGDSVPTRIQASTLSRVAREMGANIIRHGDPHAPVTMTLSL
                     GPEVIRLVSTNRVRDTGAHLPRSGTGILGMRERLAAIGGTLTTLSDDGSWMVTATVTVT
                     DSRPILLTAEKPS"
     gene            complement(1846..2280)
                     /locus_tag="E4J16_RS00310"
     CDS             complement(1846..2280)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="E4J16_RS00310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_136192124.1"
                     /transl_table=11
                     /translation="MTIEILSAIVGSLATAVITFFISRRRYRSFLTTMAAMGGTITDAG
                     LLNTLKAIVQTVTIASVCAALGTALLMAAGSLLNPAQVIITCAVILMLAVTLAWVYGRY
                     AVLAELAHTRHLKLPYGPWGLFLAHGRFRPVASRARSSLN"
     gene            complement(2420..5182)
                     /locus_tag="E4J16_RS00315"
     CDS             complement(2420..5182)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006547767.1"
                     /locus_tag="E4J16_RS00315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lysylphosphatidylglycerol synthase transmembrane
                     domain-containing protein"
                     /protein_id="WP_136312915.1"
                     /transl_table=11
                     /translation="MTDVPPPENPERVQATSPVGIPRIGVTPVVDKSTQSPHTSAGTAA
                     PRTTTLLVDAPERHLRRAEDLLDLIVAALGLTFMIILAAYAHATTTGVTQDVQNALAVV
                     LRRVLVFPLQAIEGLITFTVPVVVIMNSLLRRAWRTAGAALLAGAGGFLLAWLSLHALN
                     AWGPSILASGLTVTASGSARIGISTVFATLAGLLTGAGERRSSPVIRHTWTAVWIVVGL
                     AVLRSAITLPGAIISILLGRLPGLAVRYAFGVDDTRAHGVALVRALRRAGIDAVRVVRM
                     DRAPAARAWTVETQTPLGYTERVRETPLTAPTALDDAEATATVVDEAPDAPPPPEVTSP
                     LLPEDSSTITPADDVDLAVVLAEASSAALTEGRLSAHRLYAVWDAEGVRRDVTVLDADR
                     QVAGFLATLWDRVRVKGLSPERGLSVRSAAEHAALMILEAGRAGVRTPALVGMAEADES
                     VLLVTEHVDGARALADLEEVGDDVLTDLWDQISRAHRAGLAHRELDSACVVLDADGAVW
                     LLGWDSGETISSELSRRVDLAQALALTASLADVERAITAASRSLSTQQLASIAPMLQRV
                     VLPAATREAMGRRGKVLQELRDALVDLTPTAHAEPAKLTRFSPRTVIMAIVGLVALWTL
                     LARMNIEQITDAVAGASIWWIIGALVFSLATYVGAGLALVAFSPVRLSLWKSTEVHLAS
                     SVVSLVAPAGVGGAAINLRFLSRNGVPTAIGVATVALVQVVQFVVTVVLLIIVAATTGQ
                     STSLTLPSGWVLLIAVVLVAVVATALFIPKVRSWVWDKIEPTYRQVWPRLVWVMSNPGR
                     LALGLGGTLLLSLSYIMSFGASLWAFGHTLSFSLLAITYLAANTVGSVVPSPGGIGPVE
                     VALTAGLVTAGVPSGVALSTAIVYRLVTFWIPIPVGWLSLHRLQRNGDL"
     CDS             5562..5711
                     /gene="allorf_0075864_0076013"
                     /locus_tag="allorf_0075864_0076013"
                     /protein_id="allorf_0075864_0076013"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MAGVRGCARRRRGAAAAGAVASWGCGWANCRGALNRPSRACSMVC
                     VSPD"
     CDS_motif       5562..5618
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MAGVRGCARRRRGAAAAGA"
                     /locus_tag="allorf_0075864_0076013_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       5619..5711
                     /prepeptide="core"
                     /locus_tag="allorf_0075864_0076013_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-3.60"
                     /molecular_weight="3082.5"
                     /monoisotopic_mass="3080.4"
                     /core_sequence="VASWGCGWANCRGALNRPSRACSMVCVSPD"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MAGVRGCARRRRGAAAAGA"
                     /leader_location="[5561:5618](+)"
     CDS             5930..6139
                     /gene="allorf_0076232_0076441"
                     /locus_tag="allorf_0076232_0076441"
                     /protein_id="allorf_0076232_0076441"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MRGLQAEPARPPGPRGRAWGRASRPRPSVVMRRFVFGGVGGAGRW
                     FVGVLCADLVCSPVRGLLRRFGVC"
     CDS_motif       5930..6043
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MRGLQAEPARPPGPRGRAWGRASRPRPSVVMRRFVFGG"
                     /locus_tag="allorf_0076232_0076441_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       6044..6139
                     /prepeptide="core"
                     /locus_tag="allorf_0076232_0076441_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.60"
                     /molecular_weight="3245.9"
                     /monoisotopic_mass="3243.7"
                     /core_sequence="VGGAGRWFVGVLCADLVCSPVRGLLRRFGVC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRGLQAEPARPPGPRGRAWGRASRPRPSVVMRRFVFGG"
                     /leader_location="[5929:6043](+)"
     CDS             6036..6209
                     /gene="allorf_0076338_0076511"
                     /locus_tag="allorf_0076338_0076511"
                     /protein_id="allorf_0076338_0076511"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MGVWVEPGGGSSACFALTSSARRFAVYYAGSVSAEGSGRVSDCLC
                     KGCGPTYKETRG"
     CDS_motif       6036..6122
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MGVWVEPGGGSSACFALTSSARRFAVYYA"
                     /locus_tag="allorf_0076338_0076511_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       6123..6209
                     /prepeptide="core"
                     /locus_tag="allorf_0076338_0076511_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.20"
                     /molecular_weight="2697.0"
                     /monoisotopic_mass="2695.3"
                     /core_sequence="GSVSAEGSGRVSDCLCKGCGPTYKETRG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MGVWVEPGGGSSACFALTSSARRFAVYYA"
                     /leader_location="[6035:6122](+)"
                     /alternative_weights="2715.0"
                     /alternative_weights="2733.0"
                     /alternative_weights="2751.0"
     misc_feature    6323..6340
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.59"
                     /tool="antismash"
     gene            6330..6479
                     /locus_tag="E4J16_RS14980"
     CDS             6330..6479
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="E4J16_RS14980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_168709428.1"
                     /transl_table=11
                     /translation="MTGEDGLLTGVLKAALERGLEAELTSHLGYEKGAADAAAHTNSLW
                     RHQP"
     misc_feature    complement(6963..6978)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.18"
                     /tool="antismash"
     gene            6999..7884
                     /locus_tag="E4J16_RS00320"
     CDS             join(6999..7205,7207..7884)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558180.1"
                     /locus_tag="E4J16_RS00320"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS5 family transposase"
                     /protein_id="WP_204519867.1"
                     /ribosomal_slippage=""
                     /transl_table=11
                     /translation="MSIDAAARHDLTDAQWGLLEPLLPAPPVRGRPRVYPLRDMINAVR
                     WRTRVGAPWRDVPARYGPWWRALRLYRAWQTDGVWERIESALVAQADAAGKIGWRVSVD
                     STTCRAHVHAAGARKDSPQLVEGEPEDHALGTSRGGWSTKVHAAVDAACGMLAGVLTAG
                     QVADCPMMIPVLDKICVQRPAGGRPRTRPQMVLADKAYSSKGNRDWLRNHHIKATIPIK
                     ADQADNRRRRGSAGGRPPAFDPVAYKDRNAVERCFGQLKQNRAMATRYDKLAVRYQATT
                     HIASIDHWLKRLT"
     gene            <7893..8632
                     /locus_tag="E4J16_RS15415"
                     /pseudo=""
     CDS             <7893..8632
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015748734.1"
                     /locus_tag="E4J16_RS15415"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="KHVLGIWAPGP"
     CDS             complement(8966..9031)
                     /gene="allorf_0079268_0079333"
                     /locus_tag="allorf_0079268_0079333"
                     /protein_id="allorf_0079268_0079333"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MKSCGSVDRVPGASRRKWCNL"
     CDS_motif       complement(8993..9031)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKSCGSVDRVPGA"
                     /locus_tag="allorf_0079268_0079333_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(8966..8992)
                     /prepeptide="core"
                     /locus_tag="allorf_0079268_0079333_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.10"
                     /molecular_weight="1044.2"
                     /monoisotopic_mass="1043.6"
                     /core_sequence="SRRKWCNL"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKSCGSVDRVPGA"
                     /leader_location="[8992:9031](-)"
     CDS             8973..9044
                     /gene="allorf_0079275_0079346"
                     /locus_tag="allorf_0079275_0079346"
                     /protein_id="allorf_0079275_0079346"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MHHFRRDAPGTRSTEPHDFNDLC"
     CDS_motif       8973..9005
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MHHFRRDAPGT"
                     /locus_tag="allorf_0079275_0079346_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9006..9044
                     /prepeptide="core"
                     /locus_tag="allorf_0079275_0079346_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.30"
                     /molecular_weight="1397.5"
                     /monoisotopic_mass="1396.6"
                     /core_sequence="RSTEPHDFNDLC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MHHFRRDAPGT"
                     /leader_location="[8972:9005](+)"
                     /alternative_weights="1415.5"
     CDS             complement(9347..9514)
                     /gene="allorf_0079649_0079816"
                     /locus_tag="allorf_0079649_0079816"
                     /protein_id="allorf_0079649_0079816"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MSVPFGSGVSGADAVGSPPVVVADRDKCVRRPGCFPSAERLRLMR
                     LKEEPGPTIV"
     CDS_motif       complement(9479..9514)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSVPFGSGVSGA"
                     /locus_tag="allorf_0079649_0079816_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9347..9478)
                     /prepeptide="core"
                     /locus_tag="allorf_0079649_0079816_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.80"
                     /molecular_weight="4664.4"
                     /monoisotopic_mass="4661.5"
                     /core_sequence="DAVGSPPVVVADRDKCVRRPGCFPSAERLRLMRLKEEPGPTIV
                     "
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSVPFGSGVSGA"
                     /leader_location="[9478:9514](-)"
                     /alternative_weights="4682.4"
     gene            9515..9685
                     /locus_tag="E4J16_RS00325"
     CDS             9515..9685
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mature_ha"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF000539.0"
                     /locus_tag="E4J16_RS00325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="plantaricin C family lantibiotic"
                     /protein_id="WP_136312916.1"
                     /sec_met_domain="mature_ha (E-value: 3.2e-09, bitscore:
                     33.8, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNAKFTSTSTAKNDLLDEITEQDYITANGGVSWLSRKLGNRGFFC
                     TLTKECQSMCN"
     gene            9741..9902
                     /locus_tag="E4J16_RS14990"
     CDS             9741..9902
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF038161.1"
                     /locus_tag="E4J16_RS14990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class II lanthipeptide, LchA2/BrtA2 family"
                     /protein_id="WP_168709430.1"
                     /transl_table=11
                     /translation="MTHENLTGTYTASELEELNDISAYGGTTPSSWPCGIGITTTICPT
                     AVCTSKCR"
     CDS_motif       9741..9815
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MTHENLTGTYTASELEELNDISAYG"
                     /locus_tag="E4J16_RS14990_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9816..9902
                     /prepeptide="core"
                     /locus_tag="E4J16_RS14990_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.30"
                     /molecular_weight="2662.1"
                     /monoisotopic_mass="2660.3"
                     /core_sequence="GTTPSSWPCGIGITTTICPTAVCTSKCR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTHENLTGTYTASELEELNDISAYG"
                     /leader_location="[9740:9815](+)"
                     /alternative_weights="2680.1"
                     /alternative_weights="2698.1"
                     /alternative_weights="2716.2"
                     /alternative_weights="2734.2"
                     /alternative_weights="2752.2"
                     /alternative_weights="2770.2"
     gene            10001..12916
                     /gene="lanM"
                     /locus_tag="E4J16_RS00330"
     CDS             10001..12916
                     /GO_process="GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0018193 - peptidyl-amino acid modification
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="lanM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="E4J16_RS00330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type 2 lanthipeptide synthetase LanM"
                     /protein_id="WP_136312917.1"
                     /sec_met_domain="DUF4135 (E-value: 1.1e-62, bitscore:
                     209.9, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.5e-35, bitscore:
                     120.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTLDATDLFPELDSIRLSDYLERMSEVSLPPSNPGDDIGPLTLP
                     ASQERTPFQHLYEAVEAATYHPGKERTHRGDLLATARSTRRRIVVDSLDSILTRPLVSL
                     LRKERDQGALRADTPHDRYREFTRRLASRPSLIRSRFPVAWTMLMTTMRNTEAFLTELV
                     RRLELDWDEITSELGIPPTDTVTSLQTGGDCHHHGRRVTTVTTSSGVRFVYKPRSMDGE
                     WAYEQIVSRLAPIIGHYRSAHVIRKEGYGYAEFVEATDDVSLVDAAGQTGGLSALFYVL
                     GCNDLHAENVLLTADGPVPIDMETMLHPYVPNQDGGSATAHHEANRLLAQSVFGTGVLP
                     MVVSRPEDPDSYYDVGLLGPQEQVNGGAFRHHAITNPFTDEMSVILTKEGTEPEPERHR
                     GTDLDEVRACSDAFASAFSRTYRALMGSRETLLNVVADCCSGLRLRYIHNPTQFYAQIL
                     STLTSPLAAGSAGLARMLALRVGLTGTSHTRLIAEEVSSLLDQDIPYFTTDTSRPHVLD
                     AAGARALLPLDRAPIDTALERIRALDETDLARQLRLIRSAFCGIVPDESIAPTARPALA
                     PRPASWAPSEDRMTLTDLAANLGGQIVARMLTDTDSRHPMTWIGPLASVETTRPWPPGV
                     LGYDLYTGRLGTALALARAGRALSDTALTRAASQIFDTTIDVVGDDPEAASPVRGTYAG
                     AAGVAWALWAAGQVLERPDWCRSSGDLLRHLWRSTRPTDPADELDTISGVIASWRVSQM
                     LGVTEPIVGHDLDKALATITDGSWKDTEVAHHSGFAHGTAGVLYTVAQHPQAQRYIPTL
                     LDHLATFWDEDSRNWFTASDRSHVNHGWCHGRAGVLLGLAAARLTQGLTDVHRSELTGL
                     TADIANDGAAYNLTYCHGSLGDYDAARWLIDHGACTDTSVLTRMEEVITPQAIARKSRD
                     PHSRYSLSDGLMIGIAGSLLHLAERIDPTITVSPTTLEVHS"
     gene            12913..15042
                     /locus_tag="E4J16_RS00335"
     CDS             12913..15042
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /locus_tag="E4J16_RS00335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_136312918.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 9.7e-28, bitscore:
                     94.1, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRHRVPVRTQVSQTECGLACCLAVLEHLGCYRSFTDARRCLRPGR
                     SGLSITELQDYLRDNGCKVRSYRAGTGRLTELPLPAIVFWEKSHFVVLEHLGRHRVKLM
                     DPALGRRTLSRATFDENYSGVILTATRGPGFQPRRRQPLHQWRLPGLTWDLDLASTGVI
                     AATTVLTYLVTLVMPMITAHLVDHVTGAPAGAGTSARTLLLATAATVVLYIVVEYVRTL
                     ATSRVVRRLGAGLMQTSFGHLLRLPLSYFATRVPGELMQRLAGVNYLRDTLSSQLVSSL
                     FDLGTAIVVLGYIWVVSPQLGLAATVILVLLLAFLLLTRQPLSRAIDEEITALMEAQGV
                     QYDAVSSIAQIKIGGYTTTMESKWRKEYDRSLTALHSRMRWQNGIVGSVSAAFQLFGPF
                     TLLLYGTTLPSTSLGQAVAVSSLAATMLAGVSGLLGTYTDFITCSNHLDRLEDIIATAP
                     EPTGGAISVIRDGRIELENLSFRYANEPVPVLDGVSLTIREGEMTALVGQSGSGKTTLA
                     KVLCSLYAPSSGQVRIGGHLLEDYDRDALRRHIGYVPQDVTLHNGTLMENLALGSDMPE
                     EEIVRHCRSLGFLDFIDSLPMGYSTQVSDLGANFSGGQRQRLAIARALLRRPRIMVLDE
                     ATSALDRLNEHRVNKVLRDLGCTRVVIAHRLETVRSADSIYVMDSGRVVEHGTHQSLIQ
                     ANSTYAALYKKGAAA"
     gene            15039..17813
                     /locus_tag="E4J16_RS00340"
     CDS             15039..17813
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF024964.4"
                     /locus_tag="E4J16_RS00340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF4135 domain-containing protein"
                     /protein_id="WP_168709431.1"
                     /sec_met_domain="DUF4135 (E-value: 6.3e-60, bitscore:
                     200.8, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.9e-11, bitscore:
                     40.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPALPTTQALTSAFDAFHPFLEAVTAQSLQQTEAAALPAHLTH
                     SVHDKILEEASRIWFRALLEEFHEFRQDAGLPMQADSQQALRRYAAHLGRPEVVAGLRL
                     RWPTADQLLRTRASMHVANAWQLAQAWQEDRQHLVSCGLIPPDFDPETVTFGKGDSHNG
                     GQSVTVLSCASGERILFKPHSADGDLLLADLLGLVSRYCGEDLTGCAPRTLAGSWGSWQ
                     EFVPAREPATPGEVSQYFYRFGLLAALLTAIGAGDLHHENVIVRGPSPCVIDTETLLQP
                     GTVGPSNRLGDILLEAGERSPGSTLMLPMRVREGAFDILLCALGVPWEQVSRKSTFTLL
                     DDGTDAVRMARSEVQIDHEANVVRLYGEVVDPVDHIDRVTAGYLRMHAALRECQEEVVS
                     LLQQSGSGTFRVVLRPTETYTKLLDASVQLSALRDARQRQGILSVLRDQDYNDDGAVGA
                     RERKDLANFDVPAFQVRADGTRLLHRGQPVSRPYFAASPVAAATTSLRRFCQRDPLFHH
                     QVLETSLGELAAGQGRPYPAPLVEGALEEDPNRCANGVLRLLERTALRGLTDEGLGASW
                     LSHLGHDGLETFELDRVMSFHDLGGLVATLVSRHPGSPLARQARAALSTRLAIQDESAG
                     TPVLSVFAGPMHGWLPDDDMAAVPPGPHVLARLCPRPEDIDLITGLSGSILAAASQPDQ
                     VGDRLVAALSRLEELLPEVRWERDWYNLAHGEVGALWAQVRARHALGLAVDEPLTKILR
                     GLQGSLEDTRLGTSWCAGASGGLIVLSDLHRMGLEAPPSTAGALAARISSQALGEDPVD
                     LSVCHGVSGCIQALLLASETGLLPEGMTQAGLLWTGAVSRARSRGTQTGAVGRTTVQGY
                     MLGWGGLLDTMHRLTRGPGTFDAVSLRPRLPAPQHHLIGGPVSPMSAVTPKTA"
     misc_feature    17568..17570
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(17836..17845)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.27"
                     /tool="antismash"
     misc_feature    complement(17852..17870)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 22.76"
                     /tool="antismash"
     gene            17886..18587
                     /locus_tag="E4J16_RS00345"
     CDS             17886..18587
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="E4J16_RS00345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_136194269.1"
                     /transl_table=11
                     /translation="MSIILTDVCQAYSGFELRDVSFEVSTGEIVGFLGPNGSGKSTTLR
                     ILLGLERPVRGTALIEGTPYAKLPQPMRTIGSILDAQWIAGGQTVTQYLNWLAIAGGLD
                     RSRIPLLLEQVDLAYAAKRRVSRLSLGMRQRLGLAGALLGDPRYLVLDEPLNGLDPEGI
                     RWFRDLLRELRDQGRGILLSSHILTEVSAVADRVVMISNGRVTGSGSLSDFEAEGSLED
                     AFFKHLAPKER"
     gene            18593..20329
                     /locus_tag="E4J16_RS00350"
     CDS             18593..20329
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="E4J16_RS00350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_136312920.1"
                     /transl_table=11
                     /translation="MRLLISELYKLYVYRWPALLLTGALAACALLDIYLALAYSSSAGS
                     YVSMALSFNELVCRLAWFTLPVLVLAGDARDGMLASVVLVRPRPRAILAAKLVSSLVAA
                     QVSALGSLVLIAAFMPLGGWPDAATALAAAAPMAARLLVLPPLAVCFGFGVAVLANLRS
                     LPWVATGLVLWSQVIEKLLFTVVGNLVPPSVGAALAPYSAAVMWLYGGWGEMGLPAFDT
                     WGFLPLAGLAALTCAAAAFLLMRTADPAGRPWGLHTVALTAEAAPAMSATPTTTASAHT
                     ATAAATPTRQAADGDAARPHLVGAPAPTTGARSRRGVLADVLAWLWASMSAHGALRRTL
                     LLTLFTAVANAAITAGVVVIFEISLTSSGALSDAESAFVAVSGGWGMLCLPLTVLTGSW
                     TYLRLIQTRELALVYTALPRRSAVITACAVHAGLQAAVVTLVSIAAGLAVLSAATSVSA
                     VLATAGLTRMLVAAPLGAVLAQLSVIGAAVLIRRPIPALAGVAGWLLLAEPLLQSSSPV
                     LERVVGRRTISALVDNLVSPSSFADETLSTTSALMWLIVLAAVLVTTAIVVERRRPGVI
                     GN"
     CDS             complement(20386..20478)
                     /gene="allorf_0090688_0090780"
                     /locus_tag="allorf_0090688_0090780"
                     /protein_id="allorf_0090688_0090780"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MVMMNWSPGASREAACSWSQPCGQRGGPGR"
     CDS_motif       complement(20449..20478)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MVMMNWSPGA"
                     /locus_tag="allorf_0090688_0090780_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(20386..20448)
                     /prepeptide="core"
                     /locus_tag="allorf_0090688_0090780_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.30"
                     /molecular_weight="2036.2"
                     /monoisotopic_mass="2034.9"
                     /core_sequence="SREAACSWSQPCGQRGGPGR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MVMMNWSPGA"
                     /leader_location="[20448:20478](-)"
                     /alternative_weights="2054.2"
     CDS             complement(20829..20918)
                     /gene="allorf_0091131_0091220"
                     /locus_tag="allorf_0091131_0091220"
                     /protein_id="allorf_0091131_0091220"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MGRRQGMASGGGRFVCLPDGSSGSSNSSA"
     CDS_motif       complement(20886..20918)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MGRRQGMASGG"
                     /locus_tag="allorf_0091131_0091220_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(20829..20885)
                     /prepeptide="core"
                     /locus_tag="allorf_0091131_0091220_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.90"
                     /molecular_weight="1619.7"
                     /monoisotopic_mass="1618.8"
                     /core_sequence="GRFVCLPDGSSGSSNSSA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MGRRQGMASGG"
                     /leader_location="[20885:20918](-)"
                     /alternative_weights="1637.7"
                     /alternative_weights="1655.7"
                     /alternative_weights="1673.7"
                     /alternative_weights="1691.8"
                     /alternative_weights="1709.8"
     gene            complement(<21542..21700)
                     /locus_tag="E4J16_RS15420"
                     /pseudo=""
     CDS             complement(<21542..21700)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611430.1"
                     /locus_tag="E4J16_RS15420"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS5/IS1182 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRPRALPYRATLDVPDATARTVSR"
     gene            21909..22856
                     /locus_tag="E4J16_RS00355"
     CDS             21909..22856
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009748421.1"
                     /locus_tag="E4J16_RS00355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_136312921.1"
                     /transl_table=11
                     /translation="MTAESPALELRDIRKRYDTPGGAIDALAGMTLTAEQHKIHAFLGP
                     NGAGKSTSLEMTVGLRTPDSGTVRTLGLDPRTARDELSRRVAIQPQEAKVFQYLRVGEL
                     LDLWSSFYDHPRPADEILDSLELAKYVERQVTKLSGGTLQRLNVALAMVSDPELLILDE
                     PSTGLDPRARERLWSVLGSWRDRGTTIVLSTHSMEEATALADSVFIVDRGRCVSSGTPK
                     ELIASFAGGPAVVFRLSGDLTEENASRLRSLGDLTVNPDRSAALMTARTDEALALLSQT
                     PGCYDLGIRQPTLGDAYLAATGTELTATTTPEED"
     misc_feature    complement(21935..21953)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 22.63"
                     /tool="antismash"
     gene            22859..23641
                     /locus_tag="E4J16_RS00360"
     CDS             22859..23641
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009748422.1"
                     /locus_tag="E4J16_RS00360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease"
                     /protein_id="WP_136312922.1"
                     /transl_table=11
                     /translation="MSTTTDSGALRSARPLTITHWREMSRNRTNFGVAILLPFFIAGVF
                     LGMDKILHSTMGGPGPDFSVMVVPIALCMLLTGTCMTLTAGPIAEYRQYGTLRILGTTP
                     VSRGQFILTHLAVRVLLAIALSVLVGVLGALLGISETAAVWRAVLVALPSSVLFLALGY
                     FIGSIVSSGQAATNIATFTGMFFLFASGVVVPLELLSDSVKRVFDFLPTSYFGDLLFWV
                     TGGVQRYETTLDFVVLTALAIVAVPLAVKTFRWEAANN"
     CDS             complement(23998..24237)
                     /gene="allorf_0094300_0094539"
                     /locus_tag="allorf_0094300_0094539"
                     /protein_id="allorf_0094300_0094539"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MVLGLGDGCHSQAPKPSPVRRSNPEALCPHARCRRKGGCQRVRWS
                     RPPGQTPFCPAGRACYSRPRGADSASALCSSSVR"
     CDS_motif       complement(24022..24237)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MVLGLGDGCHSQAPKPSPVRRSNPEALCPHARCRRKGGCQRVRWSRPPGQTPFCPAGRA
                     CYSRPRGADSASA"
                     /locus_tag="allorf_0094300_0094539_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(23998..24021)
                     /prepeptide="core"
                     /locus_tag="allorf_0094300_0094539_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.20"
                     /molecular_weight="696.8"
                     /monoisotopic_mass="696.4"
                     /core_sequence="LCSSSVR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MVLGLGDGCHSQAPKPSPVRRSNPEALCPHARCRRKGGCQR
                     VRWSRPPGQTPFCPAGRACYSRPRGADSASA"
                     /leader_location="[24021:24237](-)"
                     /alternative_weights="714.8"
                     /alternative_weights="732.8"
     CDS             24276..24497
                     /gene="allorf_0094578_0094799"
                     /locus_tag="allorf_0094578_0094799"
                     /protein_id="allorf_0094578_0094799"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MRHIQFGYVNDAGEIRANDSLGEAVTWMGDGGSAGAAAAGVVSPR
                     SDTDMAMAERVRRERMCEDFLTVVDPVG"
     CDS_motif       24276..24383
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MRHIQFGYVNDAGEIRANDSLGEAVTWMGDGGSAGA"
                     /locus_tag="allorf_0094578_0094799_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       24384..24497
                     /prepeptide="core"
                     /locus_tag="allorf_0094578_0094799_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-2.40"
                     /molecular_weight="3966.5"
                     /monoisotopic_mass="3963.9"
                     /core_sequence="AAAGVVSPRSDTDMAMAERVRRERMCEDFLTVVDPVG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRHIQFGYVNDAGEIRANDSLGEAVTWMGDGGSAGA"
                     /leader_location="[24275:24383](+)"
                     /alternative_weights="3984.5"
                     /alternative_weights="4002.5"
                     /alternative_weights="4020.5"
     CDS             24328..24474
                     /gene="allorf_0094630_0094776"
                     /locus_tag="allorf_0094630_0094776"
                     /protein_id="allorf_0094630_0094776"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MIRSVRRLHGWEMGVRRVLLRRELSAPGAIRTWRWQRGCEGNACA
                     RTS"
     CDS_motif       24328..24414
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MIRSVRRLHGWEMGVRRVLLRRELSAPGA"
                     /locus_tag="allorf_0094630_0094776_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       24415..24474
                     /prepeptide="core"
                     /locus_tag="allorf_0094630_0094776_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.90"
                     /molecular_weight="2197.5"
                     /monoisotopic_mass="2196.1"
                     /core_sequence="IRTWRWQRGCEGNACARTS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MIRSVRRLHGWEMGVRRVLLRRELSAPGA"
                     /leader_location="[24327:24414](+)"
                     /alternative_weights="2215.5"
     gene            complement(24599..25267)
                     /locus_tag="E4J16_RS00370"
     CDS             complement(24599..25267)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012301.4"
                     /locus_tag="E4J16_RS00370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_136194272.1"
                     /transl_table=11
                     /translation="MNPSTQPSPIRVAIVDDDAIVRETLSAILGQEDGIEIIATATNGI
                     EAVDLVHERMVDVVLMDVQMPELDGIKATSRILAAGGKTRVLLLTTFDDDTFLDGGIAA
                     GASGFLLKSTPAAEIATAIRTVHGGGKVLSPGPTSRVLDRYVRGQRPSTSSTAELDLSG
                     REREVLRLLCQARSNRQIARQMNVAETTVKTHVSSLMRKMGVGSRLEIVTEAYKRGIGG
                     "
     gene            complement(25264..25524)
                     /locus_tag="E4J16_RS00375"
     CDS             complement(25264..25524)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="E4J16_RS00375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_136312923.1"
                     /transl_table=11
                     /translation="MIKYAAPDAQCTIQLDITDTTAELHAINPLSDTRHTTPATSSKLG
                     ILGIQERTHALGGTTTTKHTNHQWILHTTLPLTPNNAKDKP"
     gene            complement(25665..27587)
                     /locus_tag="E4J16_RS00380"
     CDS             complement(25665..27587)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF019350.4"
                     /locus_tag="E4J16_RS00380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="histidine kinase"
                     /protein_id="WP_136312924.1"
                     /transl_table=11
                     /translation="MFALPHPALNVAPRRLRAAWRARRELSVFTAFSLALSALPVLLQR
                     FTLADAVGLVVPWALLLIPRNPWTATIILAAGTAHGLVDARGPGLLMAGCFATYALFRR
                     GGYLQAVVMVVAMMAGNLLAWHAGTKMDDLFISQALWIVICIGIAAPLRLADANVSRAQ
                     AAHAQALRDQRALIARELHDTLARANTQIVLRAQQAQTHLHTPNHANQINTALDDIITT
                     GHQSVLDLRTMLRLLRQDTNTPLDPAPPTPDLATTLAQARHNLQSAGLRATVTHQGDPT
                     RLTPTLTTTLTRILDECVANMIKYAAPDAQCTIQLDITDTTAELHAINPLSDTRHTTPA
                     TSSKLGILGIQERTHALGGTTTTKHTNHQWILHTTLPLTPNNEDEPRHHTSDAHRNMDR
                     WGRTRNWSRTHWRLWLLTALSLAVSALPVLLQRFTLADAVGLVVPWALLLIPRNPWTAT
                     IILALSAVHVTASNQFTGTVIATTAAICVFIRRGGYLQAVVMVVAMVAGNLLAWHAGHD
                     MHYSLPTQLLWLVLCLGIASALRLADANVSRAQAAHAQALRDQRALIARELHDTLARAN
                     TQIVLRAQQAQTHLHTPNHANQINTALDDIITTGHQSVLDLRTMLRLLRQDTNTPLDPA
                     PPHPT"
     CDS             complement(27636..27770)
                     /gene="allorf_0097938_0098072"
                     /locus_tag="allorf_0097938_0098072"
                     /protein_id="allorf_0097938_0098072"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MTHATSKHRLHNTFLSRRSFGQSEDAIAGIRECSGFPPRPVLPW"
     CDS_motif       complement(27684..27770)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MTHATSKHRLHNTFLSRRSFGQSEDAIAG"
                     /locus_tag="allorf_0097938_0098072_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(27636..27683)
                     /prepeptide="core"
                     /locus_tag="allorf_0097938_0098072_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.00"
                     /molecular_weight="1736.0"
                     /monoisotopic_mass="1734.9"
                     /core_sequence="IRECSGFPPRPVLPW"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTHATSKHRLHNTFLSRRSFGQSEDAIAG"
                     /leader_location="[27683:27770](-)"
ORIGIN
        1 tcgcggccag ggtctccacc gggtcctcct tcgcgatgaa gccgcgcacg ccggcggcca
       61 gtgcccggtc caccaccgag tcggccacga aggtggtcag tacgagtatg gcgatctcgg
      121 ggtgctcgcg atgcaggatc tttgccaggg cgatgccgtc cagacgcggc atctgcacgt
      181 cgagcagtag cacctgcaca ttcgcctccg gcgtctgcga acgcaggatc tccagggcct
      241 cctgcccgtc gcgggccgcc cattcgacgt gtatgtcgtc aatggcctcg gtggtgagca
      301 ggtcggtgag tgtgcggcgc acgagtgcgt cgtcgtcaac gatgcctacg tgaatcatga
      361 cggtttctcc gcggtcagga ggatggggcg tgagtcggtt acggtgacag tggcggtgac
      421 catccaggag ccgtcgtcgg acagggtggt cagggtgccg ccgatggcgg ccaggcgctc
      481 ccgcatgccc aggatgccgg ttccggagcg gggcagatgt gcgccggtgt cgcggacgcg
      541 gttggtggac accagccgga tgacctccgg gccgagggag agggtcatgg tgaccggcgc
      601 gtggggatcg ccgtggcgga tgatgttggc acccatctcc ctggccaccc gggacagggt
      661 gctggcctgg atgcgggtgg ggacggagtc acccagatga cggtaggtga tgtcgaaccc
      721 ggcggaggag acgtcggcgc tgatggcgcc caccgcggta cgcaggtcgg ttaccgcgtt
      781 acccaggccg gtggtggcgg agatcgactt ctcctgctcg gaggagggag tgcgcagcgt
      841 gcgcagcagc agccgcagct catggagcgc gtccgaggca gtcgcctcga gggcggtgaa
      901 ctcgctgcgg gcgcggtccg ggtaggaggt gtcggcggcg gcgcgttggg cacgcagcgc
      961 cgtctgcgac atggagtagg cgactagatc gtgcatctcc cgggcgatct ccaggcgcat
     1021 ctcctcgagc tgggcgtccg cctgctcagc ctcggccagg cgtgaggcct cgacgaagcg
     1081 catcagtgct ccgagcggaa ccaggagggc gcccatcagg gccgtgtacc acagtgtccc
     1141 cagcgtgttg ccgatcgcgt tcccgggcga gctcagcgat accagcagaa cggcttcgac
     1201 cagaagtgtt gcgagcagca ctgagaaggc cggccagggc gggaagaacc ggcccaggaa
     1261 gaacaggaag gccagattgc tgatggtcat gtctgagaag tccgcggccg gtatcagcag
     1321 caggagaacc cagcaggtga ggtaggcgag cacccccggt accggccgca ccgggatgac
     1381 ggtcaccgat accagggcca cggtcatgaa cgccagatcg aggggcttga ccgcctgcag
     1441 attcgcggcc aggttgaaga ccaggttccc gattccgacg atcgccccga tgaacacgta
     1501 gatacggcgg cgggacagtg gctcgggttg tcgtagaagt acgctgcggg cacgtgctgc
     1561 cagggaggcg atggcatcgc ccagcactgt catgcatccc cttccgccat gctcgctgtt
     1621 atgcgagtca ctctagcaat gctcgtcgta agcgttcccg agacgggcat gacgactccg
     1681 acattagccg tgcgtgggcg aggatactgg cgattcgcca gtgatacgac agtggtatcg
     1741 agcacctgtg ccgcatcggc ggtgttgggc ggccaggtat gggggcacga tggtggtcca
     1801 gggccgcgcg tgggtgccga tggcgattcg ggcgctcgtt cgttctcagt taagtgagga
     1861 ccgggcgcga gaagcgaccg gccggaagcg accgtgggcg aggaacagcc cccacggccc
     1921 gtagggaagc ttcaggtgac gagtgtgtgc cagctccgcg agcaccgcgt acctgccgta
     1981 aacccaggcg agcgtgaccg ccagcatcag gatgaccgcg caggtgatga tcacctgcgc
     2041 gggattcagc aggcttcccg cagccatcag cagcgcggtg ccgagggctg cgcagacgct
     2101 ggcaatggtg accgtctgca cgatcgcctt gagggtattg agcaggcccg cgtcggtgat
     2161 ggtgccgccc atggcggcca tggtcgtcag aaaactgcga taccggcggc gggagatgaa
     2221 gaaggtgatg acggcggtgg cgaggctgcc gactatggca ctaagtatct cgatggtcat
     2281 cagggactcc ttcgggatga tgtcctgccg attgtgctag taactccgct accgcgcatc
     2341 ccccgatcgg gtgatccaat cggggggcgc tgcggcccgc cggggcggcg ggtgtgctcc
     2401 ggggctgctg gtgacgcggc tacaggtcgc cgttgcgctg caggcggtgc aggctcagcc
     2461 agccgacggg gatcgggatc cagaaggtga ccaggcggta gacgatcgcg gtggacaggg
     2521 ccacgccgct gggcacgccg gcggtgacca ggccggccgt cagcgccact tccaccgggc
     2581 cgatgccgcc gggggagggg accaccgagc cgaccgtgtt cgccgccagg taggtgatcg
     2641 ccagcaggga gaaggacagg gtgtggccga aggcccacag gctggccccg aaggacatga
     2701 tgtagctcag gctcagcagg agtgtgccgc cgagtcccag cgccaaccgt cccgggttgg
     2761 acatgaccca caccagccgc ggccacacct gccggtaggt gggctcgatc ttgtcccaca
     2821 cccagctgcg caccttcggg atgaacaggg cggtggcgac gacggcgacc aggacgacgg
     2881 cgatcagcag cacccagccg ctgggcaggg tgaggctggt cgactggccg gtcgtggcgg
     2941 cgacgatgat gagcaggacc acggtgacga cgaattggac cacctggacc agtgccacgg
     3001 tggccacgcc gatcgccgtc ggcaccccgt tgcgggacag gaagcgcagg ttgatggcgg
     3061 cgccgcccac gccggccggt gcgacgagcg agaccacgga tgaggccagg tgcacctcgg
     3121 tggacttcca cagagacagc cgcaccgggc tgaaggccac cagggccagc ccggccccca
     3181 cgtaggtggc cagtgagaag accagtgcgc cgatgatcca ccagatgctc gccccggcga
     3241 cggcgtcggt gatctgctcg atgttcatgc gggccagcag cgtccacagg gccaccaggc
     3301 cgacgatcgc catgatcacg gtccgcgggg agaagcgggt cagcttggcc ggctcggcat
     3361 gcgccgtcgg cgtcaggtcc accagggcgt cacgcagctc ctgcagtacc ttgccgcgcc
     3421 gccccatggc ctcgcgggtc gcggccggca ggaccacccg ctgcagcatg ggggcgatgg
     3481 aggccagctg ctgggtgctc agggagcgcg aggccgcggt gatggcgcgt tcgacgtcgg
     3541 ccagtgaggc ggtgagcgcc agcgcctggg cgaggtcgac tcggcgggac aactcggagg
     3601 agatggtctc accggagtcc catccgagca gccagacggc gccgtcggcg tcgaggacga
     3661 cgcacgcgga gtcgagttcc cggtgggcca ggccggctct gtgcgcgcgg ctgatctgat
     3721 cccacaggtc ggtcagtacg tcgtcaccga cctcctcgag gtccgccagg gcgcgggcgc
     3781 cgtccacatg ctcggtcacc agcaggacgg actcgtcggc ctccgccata cccaccaggg
     3841 cgggggtgcg cacgccggcg cgacccgcct caaggatcat gagggccgcg tgctcggcgg
     3901 ccgagcgcac cgacaggccc cgttccggtg acagtccctt cacgcggacc cggtcccaca
     3961 gggtggccag gaagcccgcc acctgccggt cggcgtccag tacggtgacg tcccggcgca
     4021 cgccctcggc gtcccagacg gcgtacaggc ggtgggctga cagccgcccc tcggtgagtg
     4081 ccgcggagga ggcctcggcc aggacgacgg cgaggtcgac gtcgtcggcg ggggtgatcg
     4141 tggaactgtc ctccggtagc agtggagagg tcacctcggg cgggggtggg gcgtccgggg
     4201 cctcgtcgac gacggtggcg gtggcctcgg cgtcgtcgag tgctgtgggt gcggtcaggg
     4261 gggtctcgcg gacgcgctcg gtgtatccca gcggcgtctg ggtctcaacc gtccaggcgc
     4321 gggcggcggg ggcgcggtcc atgcgtacga cgcggacggc atcgatgccg gcgcgacgca
     4381 gggcccgcac cagggcgacg ccgtgggcac gcgtgtcgtc gaccccgaag gcgtagcgca
     4441 cggcgagtcc gggcaggcgt cccagcagga tggagatgat ggctcccggc agggtgatcg
     4501 cgctgcgcag gaccgccagc cccaccacga tccacacggc ggtccaggtg tgccgaatga
     4561 cgggggagga ccgacgctcg cccgcacccg tgagcaggcc cgccagggtg gcgaacaccg
     4621 tggagatgcc tatacgggcg gagccggagg cggtcacggt caggccggag gcgagaatgc
     4681 tggggcccca cgcgttcagg gcgtgcaggc tcagccaggc caggaggaag cctccggctc
     4741 cggccagcag ggccgcgccc gccgtccgcc aggcacggcg cagcaggctg ttcatgatca
     4801 ccaccactgg gacggtgaag gtgatcagac cctcgatggc ctgcaggggg aagacgagga
     4861 cgcggcgcag cacgactgcg agcgcgttct gcacgtcctg ggtgacgccg gtggtggtgg
     4921 cgtgggcgta ggccgccagg atgatcatga aggtcaggcc gagtgcggcc acgatcaggt
     4981 cgagcaggtc ctcggcgcgg cgcaagtggc gctcgggggc gtccaccagc agtgtcgtcg
     5041 tccgaggggc cgcggtgcct gcggaggtgt ggggggactg cgtcgacttg tcgacgacgg
     5101 gagtgacgcc aatgcgcgga atgccgaccg gcgaagtcgc ctggacgcgt tccgggttct
     5161 ccgggggcgg gacatctgtc atgtcggtgt caacctgttg gcctacggat cgtgcagccc
     5221 caaccggggc gaaacgagcg taccaggcgg accctgggac gccgcgggac acccggtggg
     5281 taccagccgg gagagcggcc gcgaatcggg tgggctcgga gtgcgtgggc tcggagtggc
     5341 gcagcgaggc gaccgggtca catttgtcca acgggtggac tcaatcagtg tggatcggcc
     5401 gattggctgt ccgatccgac tagccgatcg gccgatgttg agagtctcga cgcttggcag
     5461 acttatcgcc gtcggcacgc aagagccgag ctgactagtc cctgaacctc cctggttagt
     5521 tcgggccggg cccctcagcg gggctcggcc cgaaccgctt tttggcgggt gtgcgtgggt
     5581 gtgctcggcg tcggcgtggg gctgccgctg cgggagcggt ggcatcgtgg ggctgcggct
     5641 gggcgaactg tcggggagca ctgaaccgtc ctagccgagc gtgttcaatg gtctgtgtga
     5701 gccctgattg agagcacctg ctgtcatgag tgtgactgat gagaagaagg ccgccgcgtg
     5761 ggaggccgtt ccggctggta gtggtgtggt ccgggagccg gctgccttgc ggcgcgcttg
     5821 atgacggcct gtttgagcag gtcgagtccg gcagggtgga gctgactgga gctgactggt
     5881 gctgactgtg ctggcggtct gctgccggcc ttgttgaagg gcccccgggg tgcggggcct
     5941 gcaggcagag ccggctcgac cacctgggcc acggggaagg gcatggggaa gggcgagccg
     6001 accaaggccg tccgtggtaa tgcggcgctt cgtgtttggg ggtgtgggtg gagccgggag
     6061 gtggttcgtc ggcgtgcttt gcgctgacct cgtctgctcg ccggttcgcg gtttactacg
     6121 ccggttcggt gtctgctgaa gggtccggga gggtgtcaga ttgtttgtgt aaggggtgtg
     6181 gtccgaccta caaggagacg agagggtgag tatgactgct gctgaagacc gggctgcggc
     6241 tggtgagcgg cagcgtgaga tcgcggagga gctgaaggcc tcgggcgcgt cggggtgaga
     6301 tcttcgcgca gatcgatgcc ggtaccccgt tgactggaga ggatgggctg ctgaccggcg
     6361 tgctcaaggc ggccctggag cggggtcttg aggccgagct gaccagccac ttgggctacg
     6421 agaagggcgc tgccgacgcc gcggcgcata ccaactccct ttggcggcac cagccgtaag
     6481 acgatcagca cttaaggatc ggggatgtcg acccggaggt cgtgccgcag gggtagggcc
     6541 ggcaccttca ccccgatgct ggtacccaag ggacagcgcc gcccgggggc ggcctggacg
     6601 ggatgatcac ccggcctgta cgccggcggc attgagggtg cgggacaccc cggcatcatt
     6661 tggcctcgac catcggcacc gagccggtgc cacgagacga tcagcaagat caccgaccag
     6721 acctggcagg ggaggtgctg gcctggcccc gccggccgcc gggtggccca cctacccggt
     6781 gattctgcca ggggcgcgat cgtggccggg atccgcgacg gggcccatgt ctccaaccgg
     6841 gccgcgcata tcgccgttgg ggcggggcat ggacgggatt agggcgtgtt gcgttagtcg
     6901 ggtggggtgg tcggcgtggt gtgcgggatg gggtgaggcc tttggggtat cacgggtggt
     6961 gtgagaacaa accgtgacac tgccaaaggc ctcgaccgtt gagtatagac gctgccgctc
     7021 gtcatgacct gaccgatgct cagtgggggc tgctcgagcc cctgctgccc gccccgcctg
     7081 ttcgtggcag gccgcgcgtg tatccgctgc gggacatgat caacgccgta cggtggagaa
     7141 cccgggtcgg tgcgccctgg cgtgacgtac cggcccgcta cgggccgtgg tggagggccc
     7201 tgcgccctgt accgggcctg gcagaccgat ggggtgtggg agcgcatcga gtccgccctt
     7261 gtcgcccagg ccgacgccgc cggcaagatc ggctggcggg tgtcggtgga ttcgaccacc
     7321 tgtcgggcgc atgtgcatgc cgctggggcg cgcaaggaca gtccccagct ggtggagggg
     7381 gagcccgagg atcacgccct ggggacctct cggggtggct ggtcgaccaa ggttcacgcc
     7441 gccgtggacg ccgcctgcgg catgctggcc ggggtgctga ccgccggaca ggtcgcggac
     7501 tgcccgatga tgatccccgt cctagacaag atatgtgtcc agcgtcctgc cggtggacgg
     7561 ccccgcacca ggccgcagat ggtgctggcc gacaaggcct actcctcaaa ggggaaccgg
     7621 gactggctgc gcaaccacca catcaaggcc accatcccta tcaaggcaga ccaggccgac
     7681 aaccgccgcc gacgcggcag cgccgggggc agaccgcccg ccttcgaccc cgtggcctac
     7741 aaggaccgca acgccgtgga gcggtgcttc ggccagctca agcagaaccg cgccatggcc
     7801 accaggtacg acaagctcgc cgtccgctac caagccacca cccacatcgc cagcatcgac
     7861 cactggctca aacgacttac ataacacgcc ctaagcacgt cctgggtatc tgggcacctg
     7921 gcccatgagg gagctaagtt ctgggccggg gtgtgcgccc gtgccggcac aaccgcggcg
     7981 tcctaggggc gtgctgatcg tgtgccgggc gggctgaccg ggttccctga ggcgatcgag
     8041 gcgacctggc cacaggccac cgccccggac ctgcgtagtg cacccgggtc cgggctgcca
     8101 cacggttcgt gtcctacaag gaccgcaagg ggcgtgtgcg ccgcgttgcg gccgaccctg
     8161 ccaggccgcc aacgaggagg ccgccccggg gtggccctgg cggccttcga ggccagcgaa
     8221 ctcggccagc gctacccggc ggcggacaca ggccttcacc gacgcctggg agaggaacac
     8281 cgccgttcct ggcgtactcc ggccgatgct gcgccgggtc atctctcccc cacttcgtgg
     8341 gaggtacccc ctccaccaac agtatcgagt cgcccagcta ccagctgcgc aaggtgtcga
     8401 agaacagggg ccagcacccg ctccgatgag gccgcggtga agctgttgtg gctggcgatc
     8461 tgcaacaccc gtggacaagc gcgccagaca gcgcgagaag gagaagaacc tacccgccag
     8521 caaacgcaaa gccaagggcc ggctcgtgga aggagcggta accaccaact ggaaacaagc
     8581 cctccaacaa caggccctgg cctacccaga acgaatcaac ccctacctgt aagcaacaac
     8641 ccgcttacac agaaaacttg acaggctccc gcgcgctggt cttgaccgca ctcgctcgac
     8701 gcccgcgaca ccgccccgag gacacccccc gccggccaca agtcctcctc agctccagaa
     8761 cctccgcgca ggtcccacaa cctcgctgcc ccgacgcccg agcacgacca ccccgtcccg
     8821 agcacggcct cctagccggc ggtgcacgcc gaacagcgcg cccgagcacg accacccgcg
     8881 agcccgggca cgaccacccg cgggcccgca ccaccacgcc cgcaaacgcg cagcgcccgt
     8941 gagcatccga tggtgctccc agctgtcaca gattgcacca ctttcgccgg gacgcgccgg
     9001 gaacccggtc aacagaaccg catgatttca acgatttgtg ctaggtggct cctgtccggg
     9061 caggtaaagt ggtgcaatca gtgacagctg ggcgacggtc accgtgtcga gccggcaggc
     9121 ccaccggtct cctcacccgg agacacgccg gccgccacat ccacaagcac gacgagccgg
     9181 tccagatgac ctggcggggc tgctagagga cacgccccgg ccagacctca cacctgcaaa
     9241 ccggaagcgc cacatatgtg caccctcgca cccaacccgg gtgagaaagg ctcagtgctg
     9301 ccgcaccccg tggtggagcg ggcccggtct cagcattctg gatcaactag acgatggttg
     9361 gccctggctc ctccttaagt ctcataagtc tgagccgttc tgctgatggg aagcaccccg
     9421 gacggcgaac acacttgtcc ctgtcagcaa cgacaaccgg tggggagccc acagcatccg
     9481 caccactcac acccgacccg aaaggaacac tcaaatgaac gccaagttca cctccacctc
     9541 caccgccaag aacgacctcc tcgacgagat caccgagcag gactacatca ccgcaaacgg
     9601 cggcgtctcc tggctgtcgc gaaagctcgg gaaccgcgga ttcttctgca ccctcaccaa
     9661 ggagtgccag agtatgtgca actaatcgcc ctcgcacgac aatcaaccca ccagcagcta
     9721 ccgaccgaaa ggacacgact atgacccatg agaacctgac cggcacctac accgcctccg
     9781 agctggagga gctgaatgac atcagcgcct acggcggaac aacccccagc tcctggccct
     9841 gcggcattgg catcacgacc accatctgcc cgaccgcagt atgcactagc aagtgccggt
     9901 gaccaatcgc tgaggggagg gagggagtac tgcttcctcc ctccctcccc tcacttctcc
     9961 tcctcagcac ctcctccttg acggaaagag acctccgcac atgacgaccc tggacgccac
    10021 cgacctcttc ccagagctcg acagcattcg cctgagcgac tacctcgagc gcatgagcga
    10081 ggtctcgctc ccaccctcca accccggcga cgacatcggc ccgctcaccc ttcctgccag
    10141 ccaggaacgg acccctttcc agcacctgta cgaggccgtg gaggccgcta cctaccaccc
    10201 tgggaaggag cgcacccacc gaggcgatct cctggcgacc gccaggagca cccgccgccg
    10261 catcgttgtc gactccctag acagcatcct cacccgtccc cttgtcagcc ttctccggaa
    10321 ggagcgcgat cagggggcgc tgcgggcgga cactccgcac gaccgctacc gcgaattcac
    10381 caggcgcctg gcctcccgcc cgtctctcat tcgctcacgg ttccccgtcg cctggaccat
    10441 gctgatgacc accatgagga acaccgaagc cttcctcacc gagctcgtcc gccgccttga
    10501 gctggactgg gacgagatca ccagcgagct cggcatccca cccaccgata ctgtcaccag
    10561 ccttcagacg ggaggcgact gccaccacca cggccgtcgc gtcaccaccg tcaccacgtc
    10621 cagcggcgtc cgattcgtct acaagccccg ctcgatggac ggcgaatggg cctatgagca
    10681 gatcgtctcc cgcctggcac ccatcatcgg ccactaccgc tcggctcacg tcatccgcaa
    10741 agagggctat ggctacgccg agttcgtcga ggccaccgac gacgtcagcc tggtcgatgc
    10801 tgctggacaa accggtggcc tgtcggccct gttctacgtc ctgggatgca acgacctgca
    10861 tgcggagaac gtcctgctca ccgcggacgg ccccgtaccc atcgacatgg agactatgct
    10921 gcacccctac gtccccaacc aggacggcgg tagtgcaaca gcccaccacg aggccaaccg
    10981 actactcgcc cagtcagtat tcggcacagg cgtgctgccc atggtcgtgt cacgtcctga
    11041 ggaccccgac tcctactacg acgtcggcct cctcggcccg caggagcagg tcaacggcgg
    11101 ggcgttccgc caccacgcca tcaccaaccc cttcaccgac gagatgtcag taatcctcac
    11161 caaagagggg acggagccgg agccagagcg ccatcgcggc actgacctgg acgaggtgcg
    11221 cgcctgctcg gacgccttcg cctccgcctt cagtcggacc taccgcgctc ttatgggcag
    11281 ccgcgagacg ctgctcaatg tcgtcgccga ctgctgctcg ggcctgcgcc tgcgctacat
    11341 ccacaacccg acccagttct acgcccagat cctgtccaca ctcacctccc cactcgccgc
    11401 aggctcagcc gggctcgctc ggatgctcgc cctgcgggtc gggctgacgg gcacctccca
    11461 cacgcggctc atcgccgagg aggtgagcag cctcctggac caggacatcc cctacttcac
    11521 caccgacacg agcaggcccc atgtcctcga cgccgccggc gcacgagccc tcctaccact
    11581 ggaccgggcg ccgattgata ctgcgttgga acggatccgg gcactggacg agaccgatct
    11641 ggcccgccag ctgcgtctca tccgctcggc cttctgtgga atcgttcccg acgagtccat
    11701 cgccccgacg gcccgcccgg cactcgcccc ccgcccggcg tcgtgggcgc cgagtgagga
    11761 ccgcatgacg ctcaccgacc tcgcggcgaa cctaggcgga cagatcgtcg ctcgtatgct
    11821 caccgacacc gactctcgcc acccgatgac gtggatcggc cccctcgcct cagtggagac
    11881 gacccgcccc tggccccccg gcgtactggg atacgacctc tacaccggcc gcctgggcac
    11941 cgccctcgcc ctcgcccgcg caggtcgcgc gctcagcgac acggccctca cccgcgcagc
    12001 ctcccagatc ttcgacacca ccatcgacgt ggtgggagat gatcctgagg ccgcctcccc
    12061 ggtacgagga acctacgcgg gcgccgcggg cgtggcctgg gccctgtggg cggcaggaca
    12121 ggtcctggag cgccccgact ggtgccgctc cagcggtgac ctcctgcgcc acctgtggag
    12181 gagcacccgc cccaccgacc cggcggacga gctcgacacc atcagcggag tcatcgcctc
    12241 ctggcgcgtg agccagatgc tcggcgtcac ggagcccata gtcggccacg acctcgacaa
    12301 ggcccttgcc accatcacgg acggcagctg gaaggacacc gaggtcgccc accactccgg
    12361 cttcgctcac ggcacagccg gagtcctcta caccgtcgca cagcaccctc aggctcagcg
    12421 ctacataccc acgctcctgg accacctggc caccttctgg gacgaggaca gccgtaactg
    12481 gtttaccgcc tcggaccgca gtcacgtcaa ccacggctgg tgccacggac gcgccggcgt
    12541 gctcctcggc ctcgcagccg cccggctcac ccagggactc acagacgtcc accggagcga
    12601 gctgacaggg ctgacagccg acatcgccaa cgacggggcg gcctacaacc tcacctactg
    12661 ccacggctcg ctgggcgact acgacgccgc ccgctggctc atcgaccacg gcgcatgcac
    12721 agatacctcc gtcctgaccc gcatggagga ggtcatcacc ccgcaggcca tcgcccggaa
    12781 gagtcgcgat ccgcacagtc gctactccct cagcgacggc ctgatgatcg ggatcgccgg
    12841 ctcactcctc cacctggcgg aacgcatcga ccccaccatc acagtctccc cgacaaccct
    12901 ggaggtccac tcatgaggca ccgtgtcccc gtgcgcaccc aggtctcgca gacggagtgc
    12961 ggtctcgcct gctgcctggc cgtcctggag cacctggggt gctaccgctc cttcaccgac
    13021 gcccgtcgct gcctgcgacc aggccggtct gggctgtcca tcaccgagct gcaggactac
    13081 ctgcgtgaca acggctgcaa ggtccgctcc taccgggccg ggaccggacg gctgaccgag
    13141 ctgccgctac cggcgatcgt cttctgggag aagtcccact tcgtcgtcct ggagcacctc
    13201 ggccgccatc gggtcaagct catggacccc gccctgggac gcaggacgct ctcacgcgcc
    13261 acctttgacg agaactactc cggcgtgatc ctcacagcca cgcgcgggcc cggcttccag
    13321 ccccgacgcc gccagccgct gcaccagtgg cggctgcccg gactcacctg ggacctcgat
    13381 ctggccagca cgggagtcat cgccgcgacg acggtactga cctacctcgt caccctcgtc
    13441 atgccgatga tcacggccca cctcgtcgac catgtgaccg gcgcacccgc aggcgccggg
    13501 acatcggccc gtaccctcct gctcgccaca gcagccaccg tggtgctgta catcgtcgtg
    13561 gagtacgtgc gcaccctggc tacctcacgc gtggtcagac gcctgggagc cggactcatg
    13621 cagacctctt tcgggcacct gttgcgccta cccctgtcct acttcgccac ccgcgtgccc
    13681 ggcgagctca tgcaacgcct cgccggcgtc aactacctgc gcgacacctt gtccagccag
    13741 ctggtgtctt ccctgttcga cctgggaaca gccatcgtcg tcctcggcta catctgggtc
    13801 gtctcacctc agctcggcct ggccgccacg gtgatcctcg tccttctcct cgccttcctc
    13861 ctcctgaccc gccagcccct cagtcgggcc atcgacgagg agatcaccgc gctcatggag
    13921 gcccaggggg tgcagtacga cgcggtctcc tccatcgccc agatcaagat cggcggctac
    13981 accacgacaa tggagagcaa gtggcgcaag gagtacgacc gctccctcac cgccctccac
    14041 agcaggatgc gctggcagaa cgggatcgtg ggctcggtca gcgccgcgtt tcagctcttc
    14101 ggccccttca cgctgctgct ctacggcacg acgcttccct cgacctccct ggggcaggct
    14161 gtggccgtct cctccctggc ggccacgatg ctcgccggcg tctcaggcct gctgggcacc
    14221 tacaccgact tcatcacctg ctccaaccac cttgaccgcc tcgaggacat catcgccacc
    14281 gcgcccgagc cgacgggcgg tgcgatcagc gtcatccgtg acggccgcat cgagctggag
    14341 aacttgtcct tccgctacgc caacgagccc gtacctgtgc tcgacggtgt cagcctgacg
    14401 attcgcgagg gagagatgac cgccctggtg ggccagtcgg gctccggcaa gaccactctg
    14461 gcaaaggtcc tatgcagcct ctacgccccc tcctcaggcc aggtccgcat cggaggccac
    14521 ttgcttgagg actacgaccg ggacgcgctg cgtcggcaca tcggttacgt cccgcaggac
    14581 gtcaccctcc acaacggcac cctcatggag aacctggccc tcggcagcga catgcccgag
    14641 gaggagatcg tccggcactg ccgctccctg ggcttcctcg acttcatcga cagcctcccg
    14701 atgggctact ccacccaggt gtccgacctc ggtgcgaact tctccggcgg acagcgtcag
    14761 cgcctcgcta tcgcccgggc actgctgcgc cggccccgaa tcatggtgct ggacgaggcg
    14821 accagcgccc tggaccggct gaacgagcac cgcgtcaaca aggtcctccg cgacctggga
    14881 tgcacacgag tcgttatcgc ccaccgcctg gagacagtgc gctccgccga cagcatctac
    14941 gtcatggact ccggccgagt cgtcgagcac ggcacccacc agagcctcat ccaggccaac
    15001 tccacctacg ccgccctcta caagaaaggt gctgcagcat gactgccccc gccctgccca
    15061 cgacacaggc cctgacctcc gccttcgatg ccttccaccc cttcctcgag gccgtcacgg
    15121 cgcagtccct ccagcagacc gaggccgccg cgttgcccgc ccacctcacg cacagcgtcc
    15181 acgacaagat ccttgaggag gcctcccgga tctggttccg tgccctcctt gaagagtttc
    15241 acgagttccg tcaggacgcg ggcctcccca tgcaggccga ctcccagcag gccctgcggc
    15301 gctacgccgc ccacctgggc aggccggagg tcgtcgcagg cctccggcta cgctggccaa
    15361 cagccgacca gctcctgcgt actcgcgcct cgatgcacgt cgccaacgcc tggcagctgg
    15421 cccaggcctg gcaggaggac cgccagcacc tggtctcctg cggactcatt ccgccagact
    15481 tcgacccgga gaccgtcacc ttcggcaagg gcgacagcca caacggcggc cagtccgtca
    15541 cggtcctgtc ctgcgccagt ggcgagcgca tcctgttcaa gccgcacagc gctgacggag
    15601 acctcctgct ggcagacctt ctcgggctcg tgagccgata ctgcggggag gacctgaccg
    15661 gttgcgctcc ccgtaccctt gccggctcgt ggggcagctg gcaggagttc gtccccgctc
    15721 gggagcccgc aacccccggt gaggtcagtc agtacttcta ccgcttcgga ctcctggccg
    15781 ccctcctgac cgctatcggc gctggggacc tgcaccacga gaatgtcatc gtgcgtggac
    15841 ccagcccgtg cgtcatcgac acagagacac tccttcagcc cggcaccgtg ggtccttcca
    15901 accgtcttgg ggacatcctc ctcgaggcgg gcgaaaggtc tccgggctcc acgctcatgc
    15961 tccccatgcg ggtgagggaa ggagccttcg acatcctgct gtgcgcgctg ggggtcccct
    16021 gggagcaggt ctcccgaaag tcgaccttca ccctcctcga cgacggcacg gacgccgtgc
    16081 ggatggcccg ctccgaggtg cagatcgacc atgaggccaa cgtcgtgcgc ctctacggcg
    16141 aggttgtcga ccccgtcgac cacatcgacc gcgtcactgc cggatacctg aggatgcacg
    16201 cagcactgag ggagtgccag gaggaggtcg tctcgctttt gcagcagtcc ggctcaggga
    16261 cgttccgtgt cgtgctgcgc cctacggaga cctacacgaa gctcctggac gcctccgtcc
    16321 agctgagcgc gctccgcgac gcccggcagc gacaggggat cctctccgtc ctgcgcgacc
    16381 aggactacaa cgacgacggg gccgtcgggg cgcgagagcg gaaagacctt gccaacttcg
    16441 acgtcccggc cttccaggtc cgggccgacg gaacacggct gctccaccgt ggccagccgg
    16501 tatctcgccc ctacttcgcc gcgagccccg tcgcagcggc gaccacctcg ctccggcgct
    16561 tctgccagcg cgacccgctc ttccaccacc aggttctcga gacctcgctc ggcgagctcg
    16621 ctgcggggca aggacgtccc taccccgccc ctctcgtcga gggagcgctg gaggaagacc
    16681 cgaaccgctg cgcgaatggc gtcctgaggc tcctggagcg cacggcgctg cggggtctga
    16741 ccgatgaggg tctgggcgcc tcctggctgt cccacctcgg ccacgacggc ctggagacct
    16801 tcgagctcga ccgggtcatg tcgttccacg acctcggtgg tctcgtcgcc actctggtct
    16861 ccaggcaccc cggctcgccc ctggcacggc aggcgcgagc cgcactgagc acccggctgg
    16921 cgatccagga cgagtcggct ggcaccccgg tcctgtcggt gtttgccggt ccgatgcacg
    16981 gctggcttcc agatgacgac atggctgccg tcccacctgg cccccacgtg ctcgcccgcc
    17041 tgtgcccacg gcctgaggac atcgatctca tcacgggcct gtctggcagc atcctcgctg
    17101 cggcgagcca gcccgaccag gtgggtgacc gcctcgtggc cgccctcagc cggctggagg
    17161 aactgctgcc cgaggtccgc tgggaacggg actggtacaa tctcgcccac ggggaggtag
    17221 gggccctgtg ggcccaggtc cgcgcacgcc acgccctcgg ccttgcggtt gacgagccgc
    17281 tgaccaagat cctccgcggc ctgcaaggca gcctggagga cacccggctg ggcacgtcgt
    17341 ggtgcgccgg ggcctcgggc ggattgatcg ttctgtccga cctgcaccgg atgggccttg
    17401 aagcgccgcc ctcgaccgcc ggggccctcg ccgcccggat cagcagtcag gctctgggag
    17461 aggaccccgt tgacctgtcc gtgtgccacg gggtgagcgg ctgcatacag gctcttctac
    17521 tggcctcaga gacgggactc cttcccgagg gcatgaccca ggccggctta ttgtggaccg
    17581 gggccgtaag ccgggcccgt tcccgcggta cccagaccgg cgcggtcggc cgcacgaccg
    17641 tccagggcta catgctgggg tggggcggcc tcctggacac catgcaccgg ctcacacggg
    17701 gccccggcac ctttgacgca gtgagcctgc gcccccgcct gcccgccccg cagcatcatc
    17761 tgatcggagg acccgttagc ccgatgtcgg ccgtcacccc gaaaacggcc tgacaaacac
    17821 acaacaactg actgtccaaa aaacacccat cactccaaac cgttctcaac catgggagta
    17881 tcaccatgtc catcatcctg actgacgtgt gccaggccta ttcgggcttc gagttgcgcg
    17941 acgtgtcctt cgaggtctcc accggcgaga tcgtcggctt cctggggccc aacggctcgg
    18001 gcaagtccac cacgttgcgc atcctgctgg gcctggagcg ccccgttcgg ggcaccgccc
    18061 tcatcgaggg gaccccttac gcgaagctgc ctcagccgat gcgcaccatc ggctccatcc
    18121 tcgacgccca gtggatcgct gggggccaga cggtgacgca gtacctgaac tggctggcca
    18181 tcgccggggg cctggaccgc tcccgcatcc ccctgctgct agagcaggtc gacctggcct
    18241 acgccgccaa acgacgtgtc tcgcgcctat ccctgggcat gcgccagcgc ctgggcctgg
    18301 ccggagcgct gctgggcgac ccgcgctacc tcgttctgga cgagccgctc aacggactgg
    18361 accccgaggg catccgctgg ttccgtgacc tgctacgaga gctacgagac cagggccggg
    18421 gcatcctgtt gtcctcccac atcctgaccg aggtctccgc cgtagccgac cgcgtcgtca
    18481 tgatctccaa cggacgcgtc accggcagtg gcagcctgag cgacttcgag gcggaaggca
    18541 gcctggaaga cgccttcttc aagcacctcg cccccaagga gcggtgatag cgatgcgact
    18601 gctcatcagc gagctctaca agctctacgt ctaccggtgg cccgccctgc tgctgacagg
    18661 agcactggcc gcctgcgccc tcctggacat ctacctcgcc ctggcgtact cctcctccgc
    18721 cggctcctat gtgagcatgg cactgagctt taacgagctt gtctgccgcc tggcgtggtt
    18781 cactctgccc gtcctggtcc tggccggtga cgcgcgtgat ggcatgctgg ccagtgtcgt
    18841 cctggtccgt ccgcgtccgc gcgcgatcct ggccgccaag ctcgtctcct cccttgtcgc
    18901 cgcccaggtc agcgccctgg ggtccctggt cctcatcgcg gccttcatgc cgctgggagg
    18961 ctggcccgac gccgccaccg ccctggccgc cgccgccccg atggccgctc gcttgctggt
    19021 gctgccgccg ctggcagtgt gcttcggttt tggcgtggcc gtcctggcca acttgaggtc
    19081 actgccgtgg gtggcgacgg gactggtcct ctggagccag gtgatcgaga agctcctctt
    19141 caccgtcgtg ggcaacctcg tgcctccgtc cgtcggagcg gccctggccc cgtattccgc
    19201 cgctgtcatg tggttgtacg gcggctgggg cgagatgggc ctgcctgcct ttgacacctg
    19261 gggcttcctg ccgctggcgg gcctggccgc cctcacctgt gcggccgccg ccttcctcct
    19321 catgcgtacc gccgacccgg ccggacggcc ctggggcctg cacaccgtcg ctctgaccgc
    19381 cgaggccgca cccgccatga gcgccacccc gacgacgacc gcctccgcgc ataccgccac
    19441 ggccgcagca accccgacgc gtcaggcggc cgacggcgac gccgctcgcc ctcacctggt
    19501 gggagcgcct gcccccacta ccggggccag gtcccgcagg ggtgtgttgg ctgatgtcct
    19561 ggcctggctt tgggccagta tgagcgccca cggagcgttg cggcgcacgc tgctcctgac
    19621 cctgttcacc gccgtcgcga acgccgccat cactgccggc gtggtggtca tcttcgagat
    19681 ctccctgacc tcctccggtg ccctcagtga cgccgagtcc gcgttcgtgg ccgtcagcgg
    19741 cgggtggggc atgctctgcc tgccgttgac cgtcctgacc ggctcgtgga cctacctgcg
    19801 tctcatccaa acccgcgagc tggccctggt ctacacggct cttccgcgtc gcagcgccgt
    19861 catcaccgcc tgcgcggtcc acgccggcct ccaggcggcg gtggtcaccc tggtgtccat
    19921 cgccgcgggt cttgcggtcc tgagcgctgc caccagcgtc agcgccgtcc tggccactgc
    19981 cggtcttacc cggatgttgg tcgccgcccc gctgggcgcc gtcctcgccc agctcagcgt
    20041 catcggagcc gccgtcctca tccgccggcc gatccccgcc ctggcgggcg tggccggctg
    20101 gctcctgctg gctgagcccc tcctccagag cagcagcccg gtcttggagc gagtagtcgg
    20161 tagacgcacc atcagcgctc tggttgacaa cctcgtcagt cccagctcct tcgccgacga
    20221 gaccctgagc accacttcgg cccttatgtg gctcatcgtg cttgccgccg tcctcgtcac
    20281 cacggcgatc gtcgtcgagc gacggcgccc aggagtcatc gggaactgac ctggacggag
    20341 caccatccgc gcaccctttc agggtggccc tggtcggcga cagcctcacc ggccagggcc
    20401 acccctctgt ccgcacggct ggctccagct gcaggcggcc tctctgcttg ccccgggcga
    20461 ccagttcatc atcaccacgg agtacgccgt tcatgccggt gccggtgacc gacctctgcg
    20521 tcctggcgga cagggcccag gttcttgatc gctgcaggct tgataaccac ccgcggccct
    20581 tcggcagtca ctaggccacc aggttttacc ggctctgcgt gtttgtgggc gtggtgtgtg
    20641 gggtgtctgg gtggtggttt gtgtgtgcgc cccggtgggt gcggtgagcg gggatgggat
    20701 ggttcaccgt gagtcccggc gggtcacggc ggatatcggc ggatcgtgcg tgagggttcg
    20761 tgcgctctgg tcgacggttc ggctcgtccg gcggcggtcc gtggggtggg tgcacgagtc
    20821 gtcgtcggtc atgccgagct gttggagctt cctgacgagc cgtcaggcaa acacacgaac
    20881 cgtccacccc ctgacgccat cccctgtcgt cggcccatga cggcccgccc gccagagccc
    20941 gccgccgatg cactcggcag tccatctggc ctgcgccagt gtcggtgtgg gtctgggggg
    21001 tgtcggggag gttctttacg acgctactta ggggattgtg acgcgactta gcggtctgct
    21061 gaaggcctcc cggggcgtac agcagagcgg tgaatggtgt tgcggacggt caagcggtgt
    21121 tgcgtacgcg cccgcggggt cggcgaccgg gatgttctcc tcgcggggtg ccgtgctcgt
    21181 gcccccaagc tccccgttgg ccctggggtt cagggacggg gacctgaccc tagtgcgtgc
    21241 cccggggttg gtggggttcg tgttccccgg tcggctgtgc ttggtaggac gggcgccatg
    21301 tcgatttacg atcttgggct gcgattcgcg accaccccgg ggtcgtaaac cagcgctggc
    21361 cagcgcttcg cgcttgaggg gcgcggccgc ccaagacaac cacgcggcag gtctccctcg
    21421 ggcgcggcag gccgtgttca ggcgcgggag gctacgcatg ggggcgcggg agatactgcc
    21481 ctcaggccga ccagaacaca ccaccagcca cccccccaaa cacaaagatc cctgttagcc
    21541 gacgcagcag catgatcgtc tgggcccagc tggtggcggc ccgctgccag ggacggacgt
    21601 cgtggcggtg gcggtgggct gcgattcacc gggacacggt gcgggcggtg gcgtcaggta
    21661 cgtcgagggt ggcacgatag ggcagcgcgc gaggcctcat tttcgggctt ggtttcttgg
    21721 tcgagacgca tgctgccgaa agactccgcg tgcactcact aacgacacac ccaccttccc
    21781 gcaccacccc aacgatccct agccccctgc cctcaaccct gatgagaaag gctcgctgaa
    21841 cccgctcgag gagtgcctgg cggcacacct ctgtgaaaca tcgtccacaa ctgaaggaga
    21901 cactcaccat gaccgccgag agccccgcgc ttgaactgcg ggatattcgc aagcgctacg
    21961 acacccccgg tggggccatt gacgccctcg cgggcatgac gctgaccgcc gagcagcaca
    22021 agatccacgc cttcctcggc cccaacggcg ccggtaagag cacctccctg gagatgacgg
    22081 tcggcctgcg cacccccgac tcgggcaccg tgcgcaccct gggcctcgac ccgcgtacgg
    22141 cacgggacga actcagtcgc cgcgtcgcca tccagccgca ggaggccaag gtcttccagt
    22201 acctgcgcgt cggcgaactg ctggacctgt ggtcctcctt ctacgaccat ccccggcctg
    22261 ccgacgagat cctcgactcc ctcgagctgg cgaagtacgt cgagcgccag gtgaccaagc
    22321 tctcgggggg cacgctccag cgtcttaacg tcgccctggc gatggtgtcc gaccccgagc
    22381 tgctcattct tgacgagcct tccaccggct tggacccgcg ggcacgggaa cgactgtggt
    22441 cggtcctcgg cagctggagg gaccgcggca cgacgatcgt cctgtccaca cactccatgg
    22501 aggaggccac cgcattggcg gactccgtgt tcattgtgga ccgtggcagg tgcgtcagct
    22561 ccgggacccc aaaggagctg atcgcctcct tcgccggagg accggcagtc gtcttccgcc
    22621 tgtcagggga cctgactgag gagaacgcct cccggctgcg gtcgctcggg gacctcacgg
    22681 tcaacccgga ccgctccgcc gctctcatga cggcgcggac cgatgaggca ctcgctctcc
    22741 tgtcccagac tcccggatgc tacgacctcg gcatccgtca gcccacgctg ggcgacgcct
    22801 atctggccgc caccggcacc gaacttaccg ctactacgac acccgaggaa gactgaccat
    22861 gagcaccacg accgacagcg gtgcgctccg cagcgcccgt ccccttacca tcacccactg
    22921 gcgggagatg tcccgcaatc ggacgaactt cggcgtcgcc atcctccttc ccttctttat
    22981 cgctggagtc ttcctgggca tggacaagat cctccactcg acaatgggag gaccgggacc
    23041 agacttctcg gtgatggtgg taccaatcgc cctgtgcatg cttctcactg ggacgtgcat
    23101 gacactgacc gccggcccga tcgccgagta ccggcagtac ggcaccctgc gtattctggg
    23161 caccaccccg gtgtcacggg gacaattcat cctgacccac cttgccgttc gagtgctcct
    23221 tgcgatcgcg ctcagtgttc tggttggagt tctgggtgcg cttctcggca tcagcgagac
    23281 cgccgccgta tggcgtgctg tgctcgtcgc cctgccctcc tccgtgctgt tcctggccct
    23341 gggctacttc atcggctcga tcgtcagttc ggggcaggct gccaccaata tcgccacatt
    23401 caccgggatg ttcttcctgt tcgcatcggg ggtggtcgtc cccctggaac tgctgtccga
    23461 ctcggtcaag cgcgtcttcg acttccttcc cacctcatac ttcggggact tgttgttctg
    23521 ggtcaccgga ggcgtgcaga gatatgagac gacgctggac ttcgtggttc tcaccgcctt
    23581 ggcgatcgtg gccgttcccc tggcggttaa gactttccgc tgggaggctg cgaataactg
    23641 agccgctcat ccgttgaatg gatggattct tctgggagga ggtagcttca tgggatgtaa
    23701 taccgactca tccttggggg tgagtacgat catggagcgt gtaagcacta tcctcgacga
    23761 gcacgatatg tgcgtccacc gtgggcgcga aggaacctcg gctcacgccg tgtttcttcg
    23821 ctccgcttga tgagcaccgc ttggtcttcg tctcatcgaa gggatcttgg cacgtggccc
    23881 atatgcgggc ggacccgcat tgctcggcac tcgtgcttcc cgagcaggcg gagcggggac
    23941 ggctggtttc cctgctcctg gcgggagagg tgacgtgccc gcaagggcgg agccggctca
    24001 gcgcaccgac gagctacata gcgcggatgc ggagtctgct cccctcggtc tcgagtagca
    24061 tgcgcggcct gctggacaaa aaggtgtttg tcctggaggc cgagaccatc gaactcgttg
    24121 acaccctcct ttgcggcggc accgtgcgtg tgggcagagg gcctcggggt tggagcgccg
    24181 gaccggggat ggttttgggg cttgggaatg acatccatcc ccaagcccca aaaccaattc
    24241 cgatcaacgg gatcggtcag cagtaagatg gtgcgatgcg acatatccaa ttcgggtatg
    24301 tgaatgatgc gggcgaaata agggctaatg attcgctcgg tgaggcggtt acatggatgg
    24361 gagatggggg ttcggcgggt gctgctgcgg cgggagttgt cagccccagg agcgatacgg
    24421 acatggcgat ggcagagagg gtgcgaaggg aacgcatgtg cgaggacttc ctgacggttg
    24481 tggatccggt gggatagccg catcttgccc cacacagctg tgtgggctgt tcatcattga
    24541 gtccccatgc gattcctcct tttgggggaa cccgacgaga catgatgagg aggggagact
    24601 agccgccgat gccccgcttg tacgcctcgg tgacgatctc cagtcggcta cccaccccca
    24661 tcttgcgcat aagcgatgag acgtgagttt tgacggtggt ctccgcaacg ttcatctggc
    24721 gtgcaatctg gcggttgctg cgtgcctggc acagaagccg aagcacttcc cgctctcgtc
    24781 ccgatagatc gagctccgcg gtggaactgg tactggggcg ctggccacgc acgtagcggt
    24841 ccaagacgcg gctggtgggt ccgggcgaga ggaccttacc gcccccgtgg acggtccgaa
    24901 ttgccgttgc gatctcggcg gcaggtgtgc tcttgagaag gaagcccgaa gcgccggcgg
    24961 cgattccgcc atcgagaaaa gtatcgtcat cgaaggtggt caataggagt acccgggtct
    25021 tgcccccggc tgcgaggata cgtgaggtgg ccttgatgcc gtccagctcc ggcatctgga
    25081 cgtccatgag cacgacatcc accatgcgtt catgaaccag atcgaccgcc tcgatgccat
    25141 tcgtggcggt ggcgatgatc tcgatgccgt cctcctggcc gaggatcgcg gatagtgtct
    25201 cgcgcacgat ggcgtcatcg tccacgatgg cgacgcggat cggactgggc tgggtgcttg
    25261 ggttcacggt ttgtccttag cgttgttggg tgtgaggggg agggtggtgt ggaggatcca
    25321 ttggtggttg gtgtgtttgg tggtggtggt tcctccgagg gcgtgggtgc gttcttggat
    25381 gccgaggatg ccgagtttgg atgaggtggc gggggttgtg tgtcgggtgt cggacagggg
    25441 gttgatggcg tggagttcgg cggtggtgtc ggtgatgtct agttggatgg tgcactgggc
    25501 gtcgggggcg gcgtacttga tcatgttggc gacgcattcg tccaggatgc gggtcagggt
    25561 ggtggtcagg gtgggggtta gccgggtggg gtctccttgg tgggtgacgg tggcgcgcag
    25621 gccggctgac tggaggttgt ggcgggcttg ggcgagggtg gtggctaggt cgggtgtggg
    25681 ggtgcggggt ctaggggggt gttggtgtct tgtcttagga ggcgcagcat ggtgcgcagg
    25741 tcgaggactg attggtggcc ggtggtgatg atgtcgtcta gggcggtgtt gatctggttg
    25801 gcgtggttgg gggtgtggag gtgggtttgt gcttgttggg cgcgtaggac gatttgggtg
    25861 ttggcgcggg cgagggtgtc gtggagctcg cgggctatga gggcgcgctg atcgcgcagg
    25921 gcctgggcgt gggcggcctg ggcccgggaa acgttggcgt ccgcaagccg cagagccgag
    25981 gcgataccca gacaaaggac gagccacaac agttgggttg gtagagagta gtgcatgtcg
    26041 tgacccgcgt gccaggccag gaggttgccg gccaccatgg ccaccaccat cacaacagcc
    26101 tgcagatagc caccccgacg gataaagaca cagattgccg cggtagtggc tataacggtt
    26161 ccggtgaact ggttgctggc tgtcacatgt acagcgctta gtgccaggat gatggtggcg
    26221 gtccaagggt tgcgggggat cagcagcagc gcccacggca ccaccagacc caccgcgtca
    26281 gcgagagtga acctctggag cagcaccggc aacgcagaga cagccagact gagcgctgtt
    26341 agcaaccaaa gtcgccaatg cgtgcgcgac cagttccgtg tgcgacccca ccgatccatg
    26401 tttcggtgag cgtccgatgt gtgatgtcta ggctcgtctt cgttgttggg tgtgaggggg
    26461 agggtggtgt ggaggatcca ttggtggttg gtgtgtttgg tggtggtggt tcctccgagg
    26521 gcgtgggtgc gttcttggat gccgaggatg ccgagtttgg atgaggtggc gggggttgtg
    26581 tgtcgggtgt cggacagggg gttgatggcg tggagttcgg cggtggtgtc ggtgatgtct
    26641 agttggatgg tgcactgggc gtcgggggcg gcgtacttga tcatgttggc gacgcattcg
    26701 tccaggatgc gggtcagggt ggtggtcagg gtgggggtta gccgggtggg gtctccttgg
    26761 tgggtgacgg tggcgcgcag gccggctgac tggaggttgt ggcgggcttg ggcgagggtg
    26821 gtggctaggt cgggtgtggg gggtgcgggg tctagggggg tgttggtgtc ttgtcttagg
    26881 aggcgcagca tggtgcgcag gtcgaggact gattggtggc cggtggtgat gatgtcgtct
    26941 agggcggtgt tgatctggtt ggcgtggttg ggggtgtgga ggtgggtttg tgcttgttgg
    27001 gcgcgtagga cgatttgggt gttggcgcgg gcgagggtgt cgtggagctc gcgggctatg
    27061 agggcgcgct gatcgcgcag ggcctgggcg tgggcggcct gggcccggga aacgttggcg
    27121 tccgcaagcc gcagaggtgc ggcgatacca atacagatta caatccacaa cgcctggctg
    27181 atgaacaggt catccatctt cgttcccgcg tgccaggcca ggaggttgcc ggccatcatg
    27241 gccaccacca tcacaacagc ctgcagatag ccaccccgac ggaagagggc gtatgtggcg
    27301 aagcacccgg ccatcagcaa tccggggcct ctagcgtcta ccagcccatg agccgtaccc
    27361 gctgccagga tgatggtggc ggtccaaggg ttgcggggga tcagcagcag cgcccacggc
    27421 accaccagac ccaccgcgtc agcgagagtg aacctctgga gcagcaccgg caacgcagag
    27481 agagccaggc tgaaggccgt gaagacgctg agttcacggc gggcgcgcca cgcagcacga
    27541 agtcgcctcg gcgcgacgtt gagtgctggg tggggcaggg cgaacatggg cggcctttca
    27601 agactgttca cagactagcc cacatcatga gcctcctacc aaggtaggac aggtcgtggc
    27661 gggaagccgg agcactcacg tatccctgcg atggcatcct cggactgtcc gaaggatcgc
    27721 ctggagagga acgtgttgtg cagccggtgc ttgctcgtgg cgtgtgtcac tcatatgcgg
    27781 gacgccaggt gctgcgggat gtggatctgg tgg
//
