LOCUS       NZ_ML974127            23390 bp    DNA     linear   CON 23-OCT-2024
DEFINITION  Halorussus salinus strain YJ-37-H Scaffold1, whole genome shotgun
            sequence.
ACCESSION   NZ_ML974127
VERSION     NZ_ML974127.1
KEYWORDS    WGS; RefSeq.
SOURCE      Halorussus salinus
  ORGANISM  Halorussus salinus
            Archaea; Methanobacteriati; Methanobacteriota; Stenosarchaea group;
            Halobacteria; Halobacteriales; Haladaptataceae; Halorussus.
REFERENCE   1  (bases 1 to 1585202)
  AUTHORS   Cui,H.-L. and Han,D.
  TITLE     Genome sequence of Halorussus salinus YJ-37-H isolated from a marine
            solar saltern
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1585202)
  AUTHORS   Cui,H.-L. and Han,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-OCT-2019) School of Food & Biological Engineering,
            Jiangsu University, 301 Xuefu Road, Jingkou District, Zhenjiang,
            Jiangsu 212013, China
REFERENCE   3  (bases 1 to 1585202)
  AUTHORS   Cui,H.-L.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-JAN-2019) School of Food & Biological Engineering,
            Jiangsu University, 301 Xuefu Road, Jingkou District, Zhenjiang,
            Jiangsu 212013, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: APR-2019
            Assembly Method                   :: SOAPdenovo v. Apr-2019
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004765815.2-RS_2024_10_23
            Annotation Date                   :: 10/23/2024 11:43:09
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,758
            CDSs (total)                      :: 4,705
            Genes (coding)                    :: 4,661
            CDSs (with protein)               :: 4,661
            Genes (RNA)                       :: 53
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 44
            CDSs (without protein)            :: 44
            Pseudo Genes (ambiguous residues) :: 0 of 44
            Pseudo Genes (frameshifted)       :: 8 of 44
            Pseudo Genes (incomplete)         :: 39 of 44
            Pseudo Genes (internal stop)      :: 6 of 44
            Pseudo Genes (multiple problems)  :: 6 of 44
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:04:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1455719
            Orig. end                         :: 1479109
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            ML974127.1.
            Bacteria and source DNA available from School of Food & Biological
            Engineering, Jiangsu University.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23390
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="5"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..23390
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23390
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13390](-)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13390)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            complement(1098..1802)
                     /gene="queC"
                     /locus_tag="EPL00_RS07320"
     CDS             complement(1098..1802)
                     /EC_number="6.3.4.20"
                     /GO_process="GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="queC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueC"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006181082.1"
                     /locus_tag="EPL00_RS07320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="7-cyano-7-deazaguanine synthase QueC"
                     /protein_id="WP_135852434.1"
                     /sec_met_domain="QueC (E-value: 1.4e-74, bitscore: 246.7,
                     seeds: 27, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTETNAEKRAVVLASGGMDSATAAYLAAEEGYDCYLLHTSYGQET
                     EDREYECARRLADDLDAADFLHVETGHLAAIGGSSLTDDEMDVADADLDSEEVPTSYVP
                     FRNANLLAMATAYAEANDCEAVFIGAHSEDFSGYPDCRPAFFDAFQNVIDAGTKDETDI
                     ELRAPFVEWSKTDIAERGVELGVPYEHTWSCYREEAPACGTCDACAFRLQAFQNVGVRD
                     PIAYDERPEYAD"
     gene            complement(1887..2129)
                     /locus_tag="EPL00_RS07325"
     CDS             complement(1887..2129)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EPL00_RS07325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_135851124.1"
                     /transl_table=11
                     /translation="MALTSGGSHSFSAFASMIVATVISKYVWNHTPSFVEVSNLAGDLL
                     VATTGVELAPQTAGSLLIASGLAFVWGVLYHVTRH"
     CDS             complement(2186..2257)
                     /gene="allorf_1457905_1457976"
                     /locus_tag="allorf_1457905_1457976"
                     /protein_id="allorf_1457905_1457976"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MSAEKPSEDEFRGASESRHRCGV"
     CDS_motif       complement(2216..2257)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSAEKPSEDEFRGA"
                     /locus_tag="allorf_1457905_1457976_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(2186..2215)
                     /prepeptide="core"
                     /locus_tag="allorf_1457905_1457976_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.60"
                     /molecular_weight="994.1"
                     /monoisotopic_mass="993.5"
                     /core_sequence="SESRHRCGV"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSAEKPSEDEFRGA"
                     /leader_location="[2215:2257](-)"
                     /alternative_weights="1012.1"
     gene            complement(2254..3078)
                     /locus_tag="EPL00_RS07330"
     CDS             complement(2254..3078)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008896642.1"
                     /locus_tag="EPL00_RS07330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="7-carboxy-7-deazaguanine synthase QueE"
                     /protein_id="WP_135851123.1"
                     /sec_met_domain="QueE (E-value: 7.9e-64, bitscore: 211.9,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1.5e-10, bitscore: 38.0,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 8.2e-28, bitscore: 94.4,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVTSDVDADAGESATRERETENASDDSGDALPINELFESLQGEG
                     RLAGVPSVFVRSSGCNLRCWFCDSYHTSWEPTHATMSVEEIVAEVESYDADHVVLTGGE
                     PLLHDASVALLEELDARGYHTTVETNGTIHRDAPIDLASVSPKLASSTPTPDETARPDG
                     KPTDADEWAERHDERRIDLDALAALVEEYDFQLKFVVSDRADVTEATDLLDRLRDAAAV
                     EIRDTDVLLMPEGATKERVAETRPVAAELAQEFGFRYTPRLHVNLWNDAPET"
     misc_feature    complement(2725..2727)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(3081..3533)
                     /locus_tag="EPL00_RS07335"
     CDS             complement(3081..3533)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTPS"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005537405.1"
                     /locus_tag="EPL00_RS07335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="6-pyruvoyl tetrahydropterin synthase family
                     protein"
                     /protein_id="WP_135851122.1"
                     /sec_met_domain="PTPS (E-value: 1e-22, bitscore: 76.9,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQRISGSPLAESGERTLYVGRDRPIRISSGHRIQHHDGKCSRPH
                     GHNYEITVKVVGELRDEGWVVDKGDITSIISEWDHRFLLEEGDPLVEAFEESGDGDALV
                     VLDAPPTAEVMSAVLERRLADELPDNVSEVAVQVSETAELCGGAEL"
     gene            complement(3634..4635)
                     /locus_tag="EPL00_RS07340"
     CDS             complement(3634..4635)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007983588.1"
                     /locus_tag="EPL00_RS07340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_135851121.1"
                     /transl_table=11
                     /translation="MPSTERRRLLRTSAAALAIGAAGCLGGGSGSTADELTTGEPTVAE
                     RPTTDSTTDDRTDGATTETPENTDSFDLPASSVRSVADVSVGVAETVARPAVAYDSIMG
                     SGGVLAPEEAQFVVAAVQSDDGSGADAAGPPTAEAFELVAGGERFPAAEIEERTTGAFT
                     TSLAGRGRVKYDDPYADGAAKGGVGWVAFEVPSPLAADSPAIRCRYGGETAVWDLPAEE
                     AAALGEPAPRFELRSFDATVADGETVELSLTAENVAEVGGELLAAVYWPTTIADDDESL
                     LVRKSVAPSGRVEWSETVDAAYAASSDGTVTASVEGCVSGTTTVALSATTTE"
     misc_feature    complement(3844..3846)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(4789..5154)
                     /locus_tag="EPL00_RS07345"
     CDS             complement(4789..5154)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006078585.1"
                     /locus_tag="EPL00_RS07345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF3006 domain-containing protein"
                     /protein_id="WP_135851120.1"
                     /transl_table=11
                     /translation="MTGEKTEVADGRYVAVVDRFEETDPARSGGERDAEGRTEDGGREL
                     AVLLLESGESVVAERAIPAWRLPADARRQDAVLELSVKNGFVVSMTHDSEETERRTDSA
                     QSRFDRLAERPGEDDES"
     gene            complement(5144..6616)
                     /locus_tag="EPL00_RS07350"
     CDS             complement(5144..6616)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008528501.1"
                     /locus_tag="EPL00_RS07350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lamin tail domain-containing protein"
                     /protein_id="WP_135851119.1"
                     /transl_table=11
                     /translation="MNRPRAPRLARVVVAVVVVSSLAGCLGGVGLGGSPDTATTDRTTA
                     DAGLAPAPGGNASDGTLSIHFLHVGQGGSVLVVGPDGETLLYDTGNWNDDGEHVLDYLR
                     ARNVSRIDYLVTSHADADHIGGHAEVIEYFETEADGIGAVYDPGIAAGTRTYEDYLDAV
                     ERHNVTLYRAQAGDEIPMAGASVRVLSPPEGYLADRERNENSLVLRVGYGNASLLLPGD
                     AERAAERYLTDRYAGALNATLLAAGHHGSNSSTGPGLLGAVGPRIAVIQSAYDSPYGHP
                     HREVLARLADRGVPTYWTGVHGTVVVETDGERAVVRTRRAAPTDPLDLRSASGVSPGAD
                     GPLERRATFAVGGSSGIVAADGGTTPESSTADADDSDTANSLAVARVHADARGDEAANL
                     NDEYVVFRNAGDRTIDLSGWVVSDEADHRYAFPAGTELAPGETLTLHTGRGTDGGGDYY
                     WNADAPVWNNAGDTVFVRDADGSLVAEVSYDG"
     gene            7055..7201
                     /locus_tag="EPL00_RS07355"
     CDS             7055..7201
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EPL00_RS07355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_162224169.1"
                     /transl_table=11
                     /translation="MSVTQHTSDVKAEIETEYARDGSDALDDSSEPMRACSCYTRICCD
                     IDS"
     gene            7324..8364
                     /locus_tag="EPL00_RS07360"
     CDS             7324..8364
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004590514.1"
                     /locus_tag="EPL00_RS07360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_135851118.1"
                     /transl_table=11
                     /translation="MRDTTPERRQRRDDEAESAESDADRVRPGDPALAVEGLSKSFGSG
                     DGAVTAVDDVSFSVGRGSIVGLLGPNGAGKTTTIKSILGMVVPDAGSVRIEDVDVHADP
                     RAAYERADAMLEGARNDYWRLTVRENLEYFASIGGEDPAAVRDRHDELLDRLDIADKAD
                     EPVRNLSRGMKQKVSLASVLARDVSVVFLDEPTLGLDVESSLQLREELGRLVRERDLTV
                     LLSSHDMDVIEAVCDRVLILNDGRIVADDSVESLLSSVELQGFRVAVADLSDATRRWVR
                     DEFEVEEMTTSADRTRFTVSTDPAGFYRLTNRFEAEEVRLEDVRTVAPDLEDVFIDVTN
                     DGGGER"
     gene            8407..9207
                     /locus_tag="EPL00_RS07365"
     CDS             8407..9207
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008005322.1"
                     /locus_tag="EPL00_RS07365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease"
                     /protein_id="WP_135851117.1"
                     /transl_table=11
                     /translation="MTEETSADRTGGHRHLWRAVLKREVVLFVRYPLNALGGFVVFLFM
                     FLVIFLGGRAFAAPALSSSIEGIVVGFFLWTLATASYVDISQDIGKDAKWGTLERHLMT
                     PFGFGVVLASKSVAKLLREAVMAVALLVVMLLLTGVELRLDVLTVVPILVATLASVFGL
                     GFAMGGLTLLYKQIGNWAALLQFGFIALVAAPTLDLGWARLLPLAQGSALLQRAMTDGT
                     RLWEFPATDLGILLATGIGYLLAGYLVFQFAQRRARRLGVLGHY"
     gene            9232..9981
                     /locus_tag="EPL00_RS07370"
     CDS             9232..9981
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024880.5"
                     /locus_tag="EPL00_RS07370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_135851116.1"
                     /transl_table=11
                     /translation="MISDVAAKYDAVASEGHADRMEASYWPVVEQVVEEIAVDASTTVL
                     DLGTGNGYAARYFASEGATVVGVDVSGEMVRVAREASDEEEAPGESEAADESATTGETE
                     TTDDGLLDFAVADMHDVPIADDSIDLAFSMDVLPYSRDLSTPLGEVARVLAPDGAFHCC
                     VNYYAEAARFQREEARGGLGMTLHSADEYADAFAAAGFRGVSQDTVPNTAIEIPPEEAF
                     PTDGWETSEDMRRTLREWGTLLTVGEL"
     gene            complement(10001..13390)
                     /locus_tag="EPL00_RS07375"
     CDS             complement(10001..13390)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="EPL00_RS07375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_135851115.1"
                     /sec_met_domain="DUF4135 (E-value: 5.2e-76, bitscore:
                     252.8, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 4.4e-48, bitscore:
                     160.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSLTEEQRAALAGRARTLHERLDAPAETRPGGTVDDVDAVLDAW
                     RDQLADGDPDRFRARLDALGLSRDDCRERLQSNAWPDDEPLPDWVATVEEVSSFVAEVA
                     PSSVESPDSERELPFEEVVGAIVAAARSRLDDEAVEETLTDAALADFEVALAERVEHVV
                     AHPLFVEFKTFVAHHDRELALADDPPEPDDPRNYYEAFVAGALDDGLREFFVEYAFLSR
                     LLASILDQWVATVEEFCGRLARDAPELAERFGDDGEGSGDDERLGGDEGLGDVTRIDVV
                     GDYHEGGRASLRVGFSSGVTLAYKPREMRVTSAFYDLLAWVNDQSRTEQSSANSSGLPE
                     LRTLDCLAREEYGWLEWAETDECATAEEVERFYRRAGVLIAMLYALRFGDGHADNVVAA
                     GDQPVVVDAETLAEPEIPPERAPHMDRAVKRVADESVVGTGLIPTTDAAGAGEAGGDGA
                     ASGGGSAGGDGGTSGDDGATGDESDATGDGGPTNVGTGAFAVVDDETGGVREPVFSEVN
                     TDLMEMDYRRVAEGSVSNLPELRGDETRPADHADRIAAGFEEGYRLLESRRDDLLADDG
                     PLSAFEDCEVRVVYRETAKYAAVLESLRTPEYLRTGLQFGCKSEALLTLFADADTGFDY
                     EPLYRAELDALARLDVPRFGASTDDTALYWDGERCVEELFDRTPYESMRERIRGLGDED
                     LAEQREYVRYAFDPETRSHGGRATEPTPDETALDPDDATFERAARDCYDRLVDAAVEGR
                     DGDPTWLVRENRPEGVSVDTLPDDLYRGRLGVALFAAALARTADEPRFAEFAEEVADPV
                     ADAVSAESVADLPLGVTGIGSVVYGFTKLGDLLDADEYVRVAETAASALTPEKIRSDGA
                     YDLLGGSAGAILGLLALHDETGSAEVVERATTAGDHLLAERADADGVPAWHSAVDGQPL
                     TGLSHGVSGIALALVRLGAVSDDRFAEAGVESLAFERRHYSPDERNWRDLRPAFDGEFG
                     DAWCNGRSGIGLARLGMAADGRGGSLDAEERRDLRDEARDALAGVEAETLQGNDHLCCG
                     NFGRVAFLNRAGTDLGDAEYRRDARRLAAASVARADRERQFRARWQTDHWHNPSLFGGE
                     AGIGYELLRLVDPSLPCVLLLE"
     gene            complement(13557..13748)
                     /locus_tag="EPL00_RS07380"
     CDS             complement(13557..13748)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF033497.1"
                     /locus_tag="EPL00_RS07380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="rubrerythrin-like domain-containing protein"
                     /protein_id="WP_135851114.1"
                     /transl_table=11
                     /translation="MAVSDGPPIGIRHPTVNPTPDAAIAQSRSGACECVDCGYVVGTDD
                     DLPPKCPDCGGALTFVRS"
     CDS_motif       complement(13656..13748)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MAVSDGPPIGIRHPTVNPTPDAAIAQSRSGA"
                     /locus_tag="EPL00_RS07380_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(13557..13655)
                     /prepeptide="core"
                     /locus_tag="EPL00_RS07380_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.80"
                     /molecular_weight="3281.7"
                     /monoisotopic_mass="3279.4"
                     /core_sequence="CECVDCGYVVGTDDDLPPKCPDCGGALTFVRS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MAVSDGPPIGIRHPTVNPTPDAAIAQSRSGA"
                     /leader_location="[13655:13748](-)"
     gene            complement(14602..15006)
                     /locus_tag="EPL00_RS07385"
     CDS             complement(14602..15006)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EPL00_RS07385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_135851113.1"
                     /transl_table=11
                     /translation="MNHVDRFRTRVAEAFGAMILTLLATVGGVMIRSAREATSATEPAT
                     LLSIDLTVGLITSLPGLVSLAGIIGATIVAGPVGLLGVLLETAGATQLLYHQSEAGFWM
                     IVFGAGLVTVGAPIPWGKVLEAFLESGGRY"
     misc_feature    complement(14869..14871)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS             complement(15003..15113)
                     /gene="allorf_1470722_1470832"
                     /locus_tag="allorf_1470722_1470832"
                     /protein_id="allorf_1470722_1470832"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MPISSIDLIQSPQLPSSAYSRVYQEGLSVFRTCRLS"
     CDS_motif       complement(15054..15113)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MPISSIDLIQSPQLPSSAYS"
                     /locus_tag="allorf_1470722_1470832_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(15003..15053)
                     /prepeptide="core"
                     /locus_tag="allorf_1470722_1470832_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.10"
                     /molecular_weight="1860.1"
                     /monoisotopic_mass="1859.0"
                     /core_sequence="RVYQEGLSVFRTCRLS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MPISSIDLIQSPQLPSSAYS"
                     /leader_location="[15053:15113](-)"
                     /alternative_weights="1878.2"
                     /alternative_weights="1896.2"
     gene            15115..15864
                     /locus_tag="EPL00_RS07390"
     CDS             15115..15864
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EPL00_RS07390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_135851112.1"
                     /transl_table=11
                     /translation="MGSEIVSRAARGLVERYNQGRERAGLNKIGPRKQRHYRRLLVYLG
                     TGGVLILTLTAIFAFFPSSVLSLVSLTLAILSISLAIFSFTQPEYWYPRDVEYLIKSTE
                     PDEWEYQEIEEESRTQFIYKNNRDIVLKFQPYSEREDFHEEWVENYMNDTAYKRQLEVT
                     HRGRRLDNVYIVSVDGGSDDIPIPSRFDRTLSEYEYELGRILNCAQAGYLARDLEDYDR
                     EYHQALKHGGISAENDSFEIDWDKASL"
     misc_feature    15340..15342
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            16230..19838
                     /locus_tag="EPL00_RS23775"
     CDS             16230..19838
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004048679.1"
                     /locus_tag="EPL00_RS23775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Eco57I restriction-modification methylase
                     domain-containing protein"
                     /protein_id="WP_135851111.1"
                     /transl_table=11
                     /translation="MTLQQITTDDIADWDSLDAIATSFEKRGLKPKPDLGDDNELVLQV
                     SDREFIVLVEAGPGESASDFKPDDRRRRTNLVATNDYEEFTFLTRTRALDGQQHGRIKH
                     QKLSFTKEQMTSKGGEKNTILQKLNSLEYDSPAAISDDLYDTKQVVREFYQEFEELRTY
                     LVQEVTGIPDDRGDAKQRYVQITLDRMIFLYFIQEKRLLDRNPNYLHEHHEQRAKNGKD
                     TYESFYEPLFFEMLAEGKQNLDFGSLPYLNGGLFSKNPIEEEFEDARLGDTPEHTNELF
                     GDILDFLSDWNWNVDERLDIVDPKNLSPAVLGHIFEQTVNQKEMGAYYTPEEITGFMSR
                     RTIHPYLLDQLNEEVGAKYDEIDDVFGFPAPDAESGVEALADGGVVTEQIPTENVETRH
                     VETLYHDFLKDTRVVDPAVGSGAFLLAAQEVLLDIYMQCIEFFQQMDDEGKTWELEERT
                     VEELERINEGRGSASLYAKRTIILNNLYGVDIDDGAVEICKLRLWLSMVADIEDEPSEV
                     EPLPNIDFNIRQGNSLIGFTDIVELTDDGDASLNNWGAGAGTGVKELYEDVIEAIERHR
                     SATSAQDAANARRVAESKISSHSGELDEKVIEQFHAAGLESVDQDSIKDFNPFHWVLEF
                     APVYEAGGFDVVIGNPPWDRIKPLRDDFFSKYDETFRTRLPDDKDSVQEELLSDEEIAQ
                     EWQEYQDEIELRAEYFKNTPAYDLQRPEIDGRINPSTNDLSSLFFERVFSLAGDDSRVA
                     QILPGAIFNGASGKDLRTHLLNNTQLDVLNLFENHGIFDGVDDRYMFGVVVFKNEGSTD
                     YVSGRYQAGDLSIFDNFGERAIRIPRDVLELYSPKARIFPHIESERKLEVLKSIIQNPA
                     IAPDDAPNGYMEPYQGLRRTSDSDRFVDKSEAEYPVYGGKNIYQYSYTPEFISDVQEPE
                     FWSVEEETDPSRSAKQRMREKTVRDLKSAIYDAFEGTGSQKGFVNDLLEQHRGKPLSES
                     DVLLDSTEYRIGLRRIARSTDERTLIATVLPKGIVCHNTLLTIPSYLITPYEEGLSEEP
                     LHNFYESMFTGDELFAKLGLLNSIPLDYLLRTKVDTGIVMYKFKESQMPDLTDGDNWFH
                     YISERAARLSCYGEEFAEMRERLGGIEPATNTQERQEIQAEIDAAAFHAYGLERREVQF
                     ILDDFHRVTNPRMMTENYFDMVFEKFDLLEEEGPFK"
     misc_feature    17649..17651
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    17787..17789
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    18072..18074
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    18807..18809
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    19314..19316
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    19704..19706
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    19812..19814
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            19866..20684
                     /locus_tag="EPL00_RS07400"
     CDS             19866..20684
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EPL00_RS07400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="endonuclease NucS domain-containing protein"
                     /protein_id="WP_135851110.1"
                     /transl_table=11
                     /translation="MVYHVDGKRVTALDPTSFDSLDLTEADIEEWIIETPSILGEDLLV
                     VASQYAKFDRAAERPDVLALDPDGKLVVIEVKRDRADKTTDLQAIKYASYCSTISAEEL
                     QQDYRAFWNKRRDEDDQLTPEKVGERFTEFLGEDIVLTEDGYADFVLDDRPRILLAAGG
                     FGPEITTPVVWLEREYGMDITCIELDVHQRDEEVFVSARQVLPIPEAEEYMAKRRQKER
                     QQSRSSSRAERAITVLLEAGLVEEGDIVLFDGESLPDDAEREYDSEDDFW"
     misc_feature    20340..20342
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS             20726..20845
                     /gene="allorf_1476445_1476564"
                     /locus_tag="allorf_1476445_1476564"
                     /protein_id="allorf_1476445_1476564"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MVGERCRILVHCPRPGGTRTSDGSRIQCQWLPVLATHRA"
     CDS_motif       20726..20797
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MVGERCRILVHCPRPGGTRTSDGS"
                     /locus_tag="allorf_1476445_1476564_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       20798..20845
                     /prepeptide="core"
                     /locus_tag="allorf_1476445_1476564_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.00"
                     /molecular_weight="1774.1"
                     /monoisotopic_mass="1773.0"
                     /core_sequence="RIQCQWLPVLATHRA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MVGERCRILVHCPRPGGTRTSDGS"
                     /leader_location="[20725:20797](+)"
     gene            complement(20966..21913)
                     /locus_tag="EPL00_RS07405"
     CDS             complement(20966..21913)
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014048.5"
                     /locus_tag="EPL00_RS07405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="endonuclease NucS domain-containing protein"
                     /protein_id="WP_135851109.1"
                     /transl_table=11
                     /translation="MPTCYLIKSGHQEYFPYWDQEDIVSVGWEKASKQVVEEVPDSDII
                     DSIEGQYDQSPGYILSVVKCFAGHEHKDRTPMEEGDIVIIVGQRKIRGKSVIRGVAEVG
                     DIDWEDERIHEDFPHQLHRDVAEWKYNGGPVVRDELSTKFQPKERSSTHLPNTLQQWNP
                     AEKDSLEVLVEELQSAPKIQPKSYDFEFDESVIQAHLRDNPEKFQDNANIVSEDIKREY
                     QTENEQFADFVFLSSESVTTVVETKVGAAGPSAVRQLKQYLQDIRSEREELVQGVLVAE
                     DFYDYEGIESELEEANITLQRYGVTLEYDQVPVE"
     misc_feature    complement(21314..21316)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
ORIGIN
        1 cgcctaccgg cgcgcgggcg acgagtggga ggcggtgaac gcgacggtcc agtcgcgggg
       61 tgagacggtt ctcctccgaa tcgcggccga cgggttcgcc ccgatagcgg tcggcgcgga
      121 gcggtcggtg acggtcgccg acgccgaact cgcggccgcg gaaatcgccg ccgacgaagc
      181 ggtcgcgctg aacgcgacct tcgagaacga cgggaactcg accgcgacgt tcgccgcgaa
      241 tctgaccgcc gacggcgaag tcgtggcgac gaagcgagtc acggtgcccg ccgaggagac
      301 cgccgaagtc acgctccgcg ccgacatcgc gccgggcacc cacgcggtcg gtctcgcggg
      361 cgagcgcgtc gggtccgaga gcgcgcgagt cggcgacgtg acggtggccg aacccaccgc
      421 ggacatctcg gtcgcggacg tgtcggtcaa cgagtccgat atcacggcgg gccagcaggt
      481 cgccatcacc gcgacggtca cgaatcgcgg gtcggcgtcg ggcgagcgcg ccctcgcgct
      541 ctcgctgttc ggcgaggagg tcgccacgaa gcgaatcgcc ctgtcggcgg gcgagcgcgc
      601 cgaggtcacc ttcgtccggc gaatcgacgc cgcgggcgag tacaccgccg aggtcgggaa
      661 cgcgacggcc gcggtgtcgg tcgaggaggt cggcgacggc gagtcggcga gtcccgaaat
      721 tccggttccc ggcttcggcg tcggggtctc ggtggtcgcg ctggtcgcgg cgctcctcgt
      781 cctccggaga cgggagtgag ttctagggga ctcgggcggt cgaactcgac gaagcaaccg
      841 ctccggcgcg tgctggcgcg acttcgtgtc gcgccatcgg cgcgcgaggg atgaggaccg
      901 caggtctgtg gccgaggacc gcaatcggtt ggggaggtgt gtggttcgcg gttgcggtgc
      961 tgtgccgttg cggtagactc cttgttgtcg gcagtagccc gcttcttccc caatcaaacg
     1021 tcgaggaaat cgcggagaca accgtagctt acagccgccc tctcatcagt ttcgaccgaa
     1081 tcctgctcga ccgaatccta gtccgcgtac tccggccgct cgtcgtacgc gatggggtcg
     1141 cgcacgccga cgttctggaa cgcctgcaac cggaacgcgc aggcgtcgca ggtgccgcag
     1201 gccggggcct cctcacggta gcaactccac gtgtgttcgt agggcacgcc caactccacg
     1261 ccgcgctcgg cgatgtcggt cttcgaccac tccacgaacg gcgcgcgcag ttcgatgtcc
     1321 gtctcgtctt tcgtcccggc gtcgatgacg ttctggaagg cgtcgaagaa cgccgggcgg
     1381 cagtcggggt agcccgagaa gtcctcgctg tgggcaccga tgaacaccgc ctcgcagtcg
     1441 ttggcctcgg cgtaggcggt cgccatcgcc agcaggttcg cgttccggaa cgggacgtag
     1501 gaggtcggga cctcctcgga gtccaagtcg gcgtcggcca cgtccatctc gtcgtcggtg
     1561 agactcgacc cgccgatggc cgcgaggtgg cccgtctcca cgtggaggaa gtccgcggcg
     1621 tcgaggtcgt cggcgagtcg ccgggcgcac tcgtactctc ggtcctcggt ctcctgtccg
     1681 taggaggtgt gcaggagata acagtcgtag ccctcctcgg cggcgaggta ggccgcggtg
     1741 gcgctgtcca tcccgccgga ggcgaggacg accgcgcgtt tctcggcgtt cgtctcggtc
     1801 atgccggacc actggaccgg caggtagatg agtcgtacgg ttccgaccag cgaggagcta
     1861 tcggtctccc gcggtgtcac acctcgtcag tgtcgcgtga cgtgatacag cacgccccac
     1921 acgaacgcga ggcccgacgc gatgaggagg ctcccggccg tctgaggcgc gagttcgacg
     1981 ccggtcgtgg cgaccagcag gtccccggcg aggttcgaca cctccacgaa cgagggcgtg
     2041 tggttccaga cgtacttcga gatgaccgtg gcgactatca tgctggcgaa cgccgagaag
     2101 gagtgcgagc cgcccgatgt gagtgccatg tggtagttac gactccctta ttatttgtcc
     2161 ctgtcacgca gtcacttaac tgtattcaga cgccacatcg atggcgcgat tcggacgctc
     2221 ctcgaaattc gtcttccgaa ggtttctccg cgctcaagtc tcgggcgcgt cgttccagag
     2281 gttgacgtgg agtcgcggcg tgtaccggaa accgaactcc tgtgcgagtt cggcggcgac
     2341 gggccgggtc tcggcgacgc gctctttggt cgcaccctcc ggcatcagga gtacgtcggt
     2401 gtcccgaatc tcgaccgcgg cggcgtcccg gagtcggtcc agcaggtccg tcgcctcggt
     2461 cacgtccgcg cggtcgctca cgacgaactt gagttggaag tcgtactcct ccacgagcgc
     2521 cgcgagcgcg tcgaggtcga tacgacgctc gtcgtggcgc tcggcccact cgtcggcgtc
     2581 ggtcggtttg ccgtcgggtc tggcggtctc gtcgggcgtc ggcgtgctgg acgccagttt
     2641 gggactcacg ctggcgaggt cgatgggcgc gtcgcggtgg atggtcccgt tggtctcgac
     2701 ggtggtgtgg tagccccgcg cgtctaactc ctccaagagc gccacggacg cgtcgtgcag
     2761 gagcggttcc ccgccggtca ggaccacgtg gtcggcgtcg taggactcga cctcggcgac
     2821 tatctcctcg acgctcatcg tcgcgtgggt cggctcccac gaggtgtgat acgagtcgca
     2881 gaaccagcac cggaggttgc accccgagga gcggacgaag acgctcggga cgcccgcgag
     2941 tcggccctcg ccctgtaggg actcgaagag ttcgttgata gggagcgcgt cgcccgagtc
     3001 gtcgctggcg ttctcggtct cgcgctctcg ggtcgccgat tcgcccgcgt cggcgtccac
     3061 gtcgctggtg acgggcatcg ctacaactcg gccccgccac agagttcggc ggtctcgctc
     3121 acctgcacgg cgacctccga gacgttgtcg ggcaactcgt cggcgaggcg acgctccagc
     3181 accgcgctca tcacctcggc ggtcggcggg gcgtcgagga cgaccagcgc gtcaccgtcg
     3241 ccggactcct cgaaggcctc cacgagcggg tcgccctcct ccagcaggaa gcggtggtcc
     3301 cactcggaga ttatcgaggt aatatccccc ttgtccacga cccagccctc gtcgcgcaac
     3361 tcgccgacga ccttgaccgt aatctcgtag ttgtggccgt gcggtcggct acacttgccg
     3421 tcgtggtgct ggatgcgatg cccgcttgag atgcggatgg ggcggtcgcg cccgacgtag
     3481 agcgtgcgct cgcccgactc cgcgagagga gacccggaga ttcgttgagc catatcacga
     3541 gattatccgg cgcgcactta acttcacgca aacggcggcc gtgtgggtcg agctggcaac
     3601 gcgagggtcg gcgggcgcga gggccgggcg cgactactcg gtcgtcgtcg ccgacagcgc
     3661 gacggtcgtc gtcccggaga cacaaccctc gacgctggcg gtcacggtgc cgtccgacga
     3721 ggcggcgtac gcggcgtcca cggtctcgga ccactcgacg cgaccgctcg gggcgaccga
     3781 cttccggacc agcaaactct cgtcgtcgtc ggcgatggtc gtcggccagt agaccgcggc
     3841 cagtaactcg cccccgacct cggccacgtt ctcggcggtc agggacagtt cgacggtctc
     3901 gccgtcggcg accgtcgcgt cgaacgaccg gagttcgaac cggggcgctg gctcgccgag
     3961 cgcggcggcc tcctcggcgg ggaggtccca gaccgccgtc tcgccgccgt accgacaccg
     4021 aatcgcgggc gagtcggcgg ccagcggcga cggcacctcg aaggcgaccc acccgacgcc
     4081 gcccttcgcg gccccgtcgg cgtacgggtc gtcgtacttg actcggcccc gtccggcgag
     4141 cgacgtggtg aacgcgccgg tcgttcgctc ctcgatttcg gccgcgggga agcgttcgcc
     4201 gcccgcgacc aactcgaagg cctcggcggt cggcggtccc gcggcgtcgg ctcccgaccc
     4261 gtcgtcgctc tggaccgcgg ccacgacgaa ctgggcctcc tcgggcgcga ggacgccgcc
     4321 cgaccccatg atggagtcgt aggcgaccgc cggtcgggcg acggtctcgg ccacgccgac
     4381 gctcacgtcg gcgaccgacc gcaccgacga cgcgggaagg tcgaaggagt cggtgttttc
     4441 gggcgtctcg gtggtcgcgc cgtcggttcg gtcgtcggta gtcgaatcgg tcgtcggccg
     4501 ctcggctacc gtcggttcgc cggtcgtcag ttcgtccgcg gtcgaaccac tgccgccgcc
     4561 gagacacccg gccgcgccga tagcgagggc ggcggcgctc gtccggagga ggcgtcgtcg
     4621 ttcggtggag ggcatacccg ccgatactcg aacgcccgac aagtgctttc tgccgaggtc
     4681 gggggtctat cgtacccgtc cgatacacat ctacacacgt ctttagaaaa tcaaattcta
     4741 tcgaagaagt atctatggaa tgccttgaaa aatctagaaa tgggtgcgct acgattcgtc
     4801 gtcctcgccc ggccgctcgg ccagtcggtc gaaccgcgac tgtgccgagt cggtccggcg
     4861 ctcggtctcc tcggagtcgt gtgtcatcga gaccacgaac ccgttcttca ccgacagttc
     4921 cagcacggcg tcctgccgcc gggcgtcggc ggggagtcgc cacgccggaa tcgcgcgctc
     4981 ggcgacgacc gactcgccgg attcgaggag caagaccgct agctcgcgcc cgccgtcttc
     5041 cgtgcgaccc tcggcgtcgc gctccccgcc gcttcgcgcc gggtcggtct cctcgaagcg
     5101 gtccacgacg gcgacgtagc gcccgtcggc cacctcggtt ttctcacccg tcatagctga
     5161 cctccgccac gagcgacccg tcggcgtcgc ggacgaaaac ggtgtcgccc gcgttgttcc
     5221 agaccggcgc gtcggcgttc cagtagtagt cgccgccgcc gtcggttccg cggccggtgt
     5281 ggagcgtcag cgtctcgccg ggcgcgagtt cggtccccgc ggggaaggcg taccggtggt
     5341 cggcctcgtc gctcacgacc caccccgaga ggtcgatggt ccggtcgccc gcgttccgga
     5401 agacgacgta ctcgtcgttc aggttggccg cctcgtctcc tcgggcgtcg gcgtggactc
     5461 gggcgacggc gagcgagttg gcggtgtcgg agtcgtccgc gtcggcggta ctcgattcgg
     5521 gagtcgtccc gccgtccgcg gccactatcc ccgaactccc gccgactgcg aacgtcgccc
     5581 gccgttccag cggcccgtcc gcgccgggcg agacgcccga cgcgctccgg aggtccagcg
     5641 ggtcggtcgg ggccgcgcgc cgggtccgga ccaccgcgcg ctcgccgtcg gtctcgacga
     5701 ccacggtgcc gtggacgccg gtccagtagg tcgggactcc tcggtcggcg aggcgcgcta
     5761 gcacttcgcg gtgcgggtgg ccgtacggcg agtcgtaggc gctctggatg acggcgattc
     5821 gggggccgac cgccccgagg agaccggggc cggtgctgga gttcgacccg tggtggcccg
     5881 cggccagcag ggtcgcgttc agcgcgccag cgtagcggtc ggtcaggtag cgttccgccg
     5941 ctcgctcggc gtcgcccggc aggaggagac tcgcgttccc gtagccgacc cggaggacga
     6001 ggctgttctc gttgcgctcg cggtcggcga ggtagccctc cggtggcgac agcacgcgga
     6061 ccgacgcgcc cgccatcgga atctcgtcgc ccgcctgcgc ccggtagagc gtgacgttgt
     6121 gccgttccac cgcgtcgagg tagtcctcgt aggtccgcgt gcccgccgcg ataccggggt
     6181 cgtagacggc cccgatgccg tcggcctcgg tctcgaagta ctcgatgacc tcggcgtggc
     6241 cgccgatgtg gtcggcgtcg gcgtgggagg tcacgaggta gtcgatgcgg gagacgtttc
     6301 gagcgcgcag gtagtcgagg acgtgttcgc cgtcgtcgtt ccagttgccg gtgtcgtaga
     6361 gcagggtctc gccgtcggga ccgaccacga ggacgctacc gccctgcccg acgtggagga
     6421 agtgtatcga gagcgtgccg tcgctggcgt tcccgccggg cgcgggcgcg agacccgcgt
     6481 cggcggtcgt tcggtcggtc gtcgccgtgt cgggcgaccc gccgaggccg accccgccga
     6541 gacaccccgc gagcgacgag acgacgacca ccgcgacgac gacgcgcgcg agtcgaggag
     6601 cgcggggacg gttcatcggg tctcctcaag gcccggagcg tcaacactct ttcccacgtc
     6661 cgagacgatt ccgtcggaac gtcgccgaat cagttcgagg agttcggaac tgtagtctac
     6721 agattcctcg actaaatact tgttagcata cagcacgaac ctacgtcaga acgaggttag
     6781 atacgttcgg cgagaggtaa ttgtatcgga aaaatagtta acaatgtacg cggcatacgg
     6841 gtcgtcgtga tatctcgtca cggagtccca ccggaacgac cgaggagtcc gcgtccggag
     6901 acgagcgtga agttgcggca cgctcggcgc ttccgcgcgt cgtcccgcgt ttttccttac
     6961 gttctatccg acacagtagt gaattcatct ccaactaaat gttaaagaca gctagaaaag
     7021 atttaacaac gtctgttgtg tataatctat cgcaatgtcc gtgacacagc ataccagtga
     7081 cgtgaaggca gagatcgaaa ccgagtacgc ccgcgacggg tccgacgccc tcgacgattc
     7141 gtcggagccg atgcgagcct gtagctgtta cactcgcatc tgttgcgaca tcgactccta
     7201 aacgaccgcg acgaccgagg tcgttttttt ttcggccgtg cgtctgtccg ctacgcccct
     7261 cggccacggc gacgagagct gacgacgatt cggcggtctt ccgccgggaa ctgactcgat
     7321 aggatgcgag atacgacacc ggaacgaaga cagagacgcg acgacgaggc cgaatccgcg
     7381 gagagcgacg ccgaccgagt gcgaccggga gacccggcac tcgccgtcga gggcctctcg
     7441 aagtcgttcg gctccggcga cggcgcggtc acggcggtag acgacgtgtc cttctcggtc
     7501 ggtcgcgggt ccatcgtcgg actcctcggg ccgaacggcg cgggaaagac gaccaccatc
     7561 aagtcgatac tcggaatggt cgtccccgac gccgggtcgg tccggataga ggatgtggac
     7621 gttcacgccg acccccgcgc ggcctacgag cgcgccgacg cgatgttgga gggcgcgcga
     7681 aacgactact ggcggctgac cgtccgcgag aacttggagt acttcgccag catcggcggc
     7741 gaggaccccg cggcggtgcg agaccgccac gacgagttgc tcgacaggct cgacatcgcc
     7801 gacaaggccg acgaaccggt ccggaacctc tcgcggggga tgaaacagaa ggtgtcgctg
     7861 gccagcgtcc tcgcccgcga cgtgtcggtc gtcttcttgg acgaaccgac gctcggactc
     7921 gacgtggaga gttccctgca actgcgcgag gagctaggcc gactcgtccg cgagcgcgac
     7981 ctcaccgtcc tcctctccag tcacgacatg gacgttatcg aggcggtctg tgaccgcgtg
     8041 ttgattctga acgacggtcg catcgtggcc gacgactcgg tcgagtcgct cctctcgtcg
     8101 gtcgaactgc agggcttccg cgtcgcggtc gccgacctct cggacgcgac tcggcggtgg
     8161 gtccgcgacg agttcgaggt cgaggagatg acgacttcgg ccgacagaac ccggttcacc
     8221 gtctcgacgg acccggcggg gttctaccga ctcacgaacc gattcgaggc cgaggaggtc
     8281 cgactcgaag acgtgcgcac ggtcgcgccg gacctcgaag acgtgttcat cgacgtgacg
     8341 aacgacggag gcggagaacg atgaccaacg ggggcgaacc atgacgaagg agagaggtgg
     8401 agaacgatga ccgaggagac cagcgccgac cggaccggcg ggcatcgcca cctctggcgc
     8461 gcggtactca agcgggaggt cgtcctgttc gtccggtacc cgctgaacgc gctcggcggg
     8521 ttcgtggtgt tcctgttcat gtttctggtc atcttcctcg gcgggcgggc gttcgccgcc
     8581 ccggcgctgt ccagttccat cgagggcatc gtcgtcggct tcttcctctg gacgctggcg
     8641 acggcctcct acgtggacat ctcccaagac atcggcaagg acgccaagtg gggcacgctc
     8701 gaacgccacc tgatgacgcc gttcgggttc ggcgtcgtgc tggcgagcaa gtcggtcgcc
     8761 aaactcctgc gcgaggcggt gatggccgtc gcgttgctcg tcgtcatgct cctgttgacc
     8821 ggcgtcgaac ttcgactcga cgtgctgacg gtcgtcccga ttctcgtcgc gacgctcgcg
     8881 tcggtgttcg gcctcgggtt cgcgatgggc ggactgacgc tcctgtacaa gcaaatcggt
     8941 aactgggcgg cgctcctcca gttcggcttc atcgcgctgg tcgccgcgcc cacgctcgac
     9001 ctcgggtggg cgaggcttct cccgctcgcg caggggagcg cgctcctcca gcgcgcgatg
     9061 accgacggga cccgcctctg ggagttcccg gcgacggacc tcggtatcct gctggccacg
     9121 ggaatcgggt atctcctcgc gggctacctc gtcttccagt tcgcacagcg acgcgcccgg
     9181 cggttgggcg tcctcggcca ctactgacca ccgaacgacc acaccgaact catgatttcc
     9241 gatgtcgccg ccaagtacga cgccgtagcg agcgagggcc acgccgaccg gatggaagcg
     9301 tcctactggc cggtcgtcga acaggtcgtc gaggagatag ccgtcgatgc ctcgaccacc
     9361 gtcttggacc tcgggaccgg caacggctac gccgcgagat acttcgcctc ggagggggct
     9421 accgtcgtcg gcgtggacgt gtccggcgag atggttcggg tcgcgcgcga ggcgtccgac
     9481 gaggaggaag cgcccggcga gtccgaagcg gccgacgagt cggcgacgac cggcgagacc
     9541 gagacgaccg acgacggact cctcgacttc gccgtcgcgg acatgcacga cgtaccgata
     9601 gccgacgaca gcatcgacct cgcgttctcg atggacgtgc ttccctactc gcgggacctc
     9661 tcgacgccgc tcggcgaggt cgcccgcgtc ctcgcgcccg acggcgcgtt ccactgctgt
     9721 gtcaactact acgccgaggc cgcccggttc cagcgcgagg aggcccgcgg cggtctcggg
     9781 atgacgctcc actcggccga cgagtacgcc gacgccttcg cggcggctgg cttccgagga
     9841 gtctcccaag acaccgtacc caacaccgcg atagagatac cgcccgagga ggcgttcccg
     9901 accgacggct gggagaccag cgaggacatg cgccggacgc tccgggagtg gggcaccctg
     9961 ctcacggtcg gggagctgta ggccgacgaa cgtccccgaa ctactccagc aacagcacgc
    10021 aggggagact cgggtccacc agtcggagca gttcgtagcc gattccggcc tcgccgccga
    10081 acagcgacgg gttgtgccag tggtcggtct gccagcgcgc ccggaactgc ctctcgcggt
    10141 cggcgcgcgc gacgctcgcg gccgccagtc ggcgcgcgtc acggcgatac tcggcgtcgc
    10201 cgaggtcggt ccccgcccgg ttcaggaacg ccacgcgccc gaagttgcca cagcagaggt
    10261 ggtcgttgcc ctgcaacgtc tcggcctcga cgcccgccag cgcgtcgcgg gcctcgtcgc
    10321 ggaggtcgcg gcgctcctcg gcgtcgagac tcccgccgcg accgtccgcg gccatcccga
    10381 ggcgagcgag accgatgccg ctccggccgt tgcaccacgc gtcgccgaac tcgccgtcga
    10441 acgccgggcg gaggtcccgc cagtttcgct cgtcgggcga gtagtggcgg cgctcgaacg
    10501 ccagactctc gacgcccgcc tcggcgaacc ggtcgtccga gaccgctccg agccggacca
    10561 gcgcgagcgc gatacccgag acgccgtgtg agagacccgt cagcggttgg ccgtccaccg
    10621 cggagtgcca cgcgggaacg ccgtcggcgt ccgcgcgctc ggccagcagg tggtcgcccg
    10681 cggtcgtcgc gcgctccacg acctccgcgc tccccgtctc gtcgtggagc gcgaggagac
    10741 cgagaatcgc gcccgcgctc ccgccgagca ggtcgtacgc cccgtccgag cgaatcttct
    10801 cgggcgtgag cgcgctcgcg gccgtctcgg cgacccggac gtactcgtcg gcgtcgagga
    10861 ggtccccgag tttggtgaac ccgtagacga ccgagccgat tcccgtgacg cccagcggga
    10921 ggtcggcgac gctctccgcg gagacggcgt cggccaccgg gtcggcgacc tcctcggcga
    10981 actcggcgaa tcgcggttcg tcggcggtgc gggccagcgc ggcggcgaac agcgcgacgc
    11041 cgagtcgccc ccggtagagg tcgtcgggga gcgtatcgac cgagacgccc tcgggtcggt
    11101 tctcccggac gagccacgtc gggtcgccgt ctcggccctc gaccgcggcg tccacgagtc
    11161 ggtcgtagca gtctctcgcc gcgcgctcga acgtcgcgtc gtcggggtcc agtgcggtct
    11221 cgtccggggt cggttccgtg gcacgcccgc cgtgcgagcg cgtctccggg tcgaaggcgt
    11281 agcggacgta ctcgcgctgt tcggccaagt cctcgtcgcc cagtccacgg attcgttccc
    11341 gcatcgactc gtatggcgtt cggtcgaaca actcctcgac gcaccgctcg ccgtcccagt
    11401 agagggcggt gtcgtcggtg gacgccccga accgcggcac gtcgaggcgg gccagcgcgt
    11461 cgagttcggc ccggtagagc ggttcgtagt cgaatccggt gtcggcgtcc gcgaacagcg
    11521 tcaggagggc ttcggactta cagccgaact ggagtccggt ccggaggtac tcgggcgtcc
    11581 ggagcgactc caacaccgcc gcgtacttgg ccgtctcgcg gtagacgacc cggacctcgc
    11641 agtcctcgaa cgccgagagc gggccgtcgt cggccagcag gtcgtcgcgc cgggattcga
    11701 ggagccgata cccctcctcg aaccccgccg cgattcggtc ggcgtggtcg gccgggcggg
    11761 tctcgtcgcc ccggagttcg gggaggttcg agacgctccc ctcggcgacg cgccggtagt
    11821 ccatctccat caggtcggtg ttcacctcgc tgaacaccgg ctcccggaca ccgccggtct
    11881 cgtcgtccac gaccgcgaac gcgccggtgc cgacgttcgt cgggccgccg tcgcccgtcg
    11941 cgtcactctc gtcgccggtc gcgccatcgt cgccgctcgt tccgccatcg ccgcctgccg
    12001 agccgccccc gcttgctgca ccgtccccgc ctgcctcacc ggccccggcg gcgtcggtgg
    12061 tcggtatcag ccccgtcccg acgaccgact cgtcggcgac ccgcttgacg gcccggtcca
    12121 tgtggggcgc tcgctcgggc ggtatctcgg gttccgccag cgtctcggcg tccacgacga
    12181 ccggctggtc gcccgccgcg accacgttgt cggcgtggcc gtcgccgaac cggagcgcgt
    12241 acagcatcgc tatcagcacg cccgcccgcc ggtagaaccg ctcgacctcc tcggcggtcg
    12301 cacactcgtc ggtttcggcc cactccagcc agccgtactc ctcgcgggcg agacagtcga
    12361 gcgtccggag ttcggggagg cccgacgagt tcgcgctcga ctgttctgtt ctcgactggt
    12421 cgttcaccca cgcgagaagg tcgtagaacg cgctcgtgac ccgcatctct cggggtttgt
    12481 acgcgagcgt gaccccggag gagaacccga cgcggagcga ggcccggccg ccctcgtggt
    12541 agtcgcccac cacgtcgatt cgggtcacgt cgcccaaccc ctcgtcgccg cccaaccgct
    12601 cgtcgtcgcc cgagccttcg ccgtcgtccc cgaaccgctc ggcgagttcg ggggcgtcac
    12661 gggcgagtcg tccgcagaac tcctcgacgg tcgcgaccca ctggtcgagt atcgacgcca
    12721 gcagtcgcga cagaaacgcg tactccacga agaactcccg gaggccgtcg tccagcgcgc
    12781 ccgcgacgaa cgcctcgtag tagttgcggg ggtcgtccgg ctccggcggg tcgtcggcca
    12841 gcgccaactc ccggtcgtgg tgggcgacga acgtcttgaa ctccacgaac agcggatggg
    12901 cgacgacgtg ttcgactcgc tcggccagcg cgacctcgaa gtccgcgagc gccgcgtcgg
    12961 tcagcgtctc ctcgacagcc tcgtcgtcca accgcgagcg agcggcggcg acgattgccc
    13021 cgacgacctc ctcgaacggg agttcgcgct ccgagtcggg actctcgacc gaggagggcg
    13081 cgacttccgc gacgaacgac gacacctcct cgacggtcgc cacccagtcg ggaagcggtt
    13141 cgtcgtccgg ccacgcgttc gactgtaggc gctcgcggca gtcgtctcgc gacagtccga
    13201 gcgcgtccag tcgcgctcgg aaccggtcgg ggtcgccgtc ggccaactgg tcgcgccacg
    13261 cgtccagtac cgcgtctacg tcgtctacgg tcccgcccgg tcgggtctcg gcgggcgcgt
    13321 cgaggcgctc gtggagcgtc cgggcgcgtc ccgccagcgc cgctcgttgc tcctcggtga
    13381 gggacggcat ataattacta cagcagttgc tcgtatttat gtgtcgtgcc cgtcgttgac
    13441 atccggttcg tcaccactcg cggtcggcgt ccgcgacgcg cgtgcggtcc gtcgagaccg
    13501 accgagtggg gactgtggct tctcggaaaa ggcgttctcc tcggtacgac accgagctac
    13561 gaccgcacga acgtcagcgc cccgccgcag tcggggcatt tcggcggcaa gtcgtcgtcc
    13621 gttccgacga cgtacccaca atcgacacac tcgcaggccc ccgaccgact ctgtgctatc
    13681 gcggcgtccg gagtcgggtt caccgtcgga tgccgaatac ctatcggtgg tccatcactt
    13741 acggccataa tcgaacagac gggacgaatc cctaaatatg ttccatagcc attagaacat
    13801 acctcagtgt tcgtctatac ttttcagtaa taccgtgatt agacggccgg tctctcgaag
    13861 attcgagggc agtgattcga gaaaacaaac gtcactactg ggcgtttggt tcggcagaga
    13921 agtgctccgt tagggatttg aaccctagtc cttgccgtga gaggccaacc caactcgcca
    13981 catcaaaccg accaacttac cggaacccct cacaccaatc cccggtctga actgatgaca
    14041 ccccgattct caacgtcgca ccttataaat cacctgttca ttgccaccta ggcaacctcg
    14101 actcaccgga ttcttttatc caatgtcccg gccataatac tatggttcgg tcgaagtccc
    14161 ttagcggcgt attagtaatg atggtgtaca tctagctgat attctgctaa catgccttca
    14221 aggacgcggt agagggtgtc gaagggagag tggacgacgt cgcttgggat aaattccggg
    14281 gtgagaacgc gtgtaccagc aactatgaat gttgtaggaa acgataacag tagttgataa
    14341 tacggtttct tattcaatct gtcattcgta accgactcgg gggttttgct caatgcgtgg
    14401 tgtagattga gcatgggaat ccctatcaat taagtgtggt attgcgaggt gcgtgctgaa
    14461 tccagagcgt gaattcagca cggcacactc atttctttca cgctgaagtc agcgaaccag
    14521 ttgttcagtg gatctgccca cctaccgaac cagaacacgc gcaggtagac ctcgaccacc
    14581 tcgctgtcgg cgtcggtctg gttagtatcg accacccgat tcaaggaacg cttccaatac
    14641 cttcccccaa gggattggcg caccgaccgt caccagaccg gctccaaaga caatcatcca
    14701 aaagcccgcc tcgctttgat ggtagagcaa ctgtgtcgcc cctgctgttt cgagtagcac
    14761 accgagaagt ccgactggcc ctgcgacaat tgtcgcgcca ataataccgg caagagaaac
    14821 gaggcccgga agcgaagtga tgagtccgac agttaggtca atagacagta acgtggcggg
    14881 ttcagttgcc gatgtggctt ctcgggcgga gcgaatcata acgcccccaa cggtcgccag
    14941 cagagttaga atcatcgcac cgaaggcttc agcgacgcgg gtacggaagc ggtcaacatg
    15001 gttcatgaga ggcgacacgt tctgaacaca gataatccct cttggtagac acgactatac
    15061 gcggatgacg gtaattgagg ggattgaata aggtctatcg aggatattgg cacaatgggt
    15121 agtgagattg tatctcgcgc ggctcgcggt cttgtggagc gctataatca gggacgggaa
    15181 cgtgctggct tgaacaaaat cggcccacgg aaacaacgac actaccgtag actactcgta
    15241 taccttggaa cgggcggcgt attgattcta actttgaccg ctatcttcgc attcttccca
    15301 tcctctgtac tttctcttgt gagcctcaca ctagcgatat tatcaatttc gctggcaatt
    15361 ttctcgttca ctcaacccga atactggtat ccccgtgatg tggaatacct gattaaatct
    15421 actgaacccg acgaatggga gtatcaagaa atagaagagg aaagccgaac tcaatttatt
    15481 tacaagaata acagagacat agtgctgaaa ttccaaccat atagtgagcg cgaagacttt
    15541 cacgaagagt gggtagagaa ctatatgaat gacacagcgt acaaacgaca actcgaagta
    15601 acccatcgag gccgtcgctt ggataacgta tatattgtgt cagttgacgg ggggagcgac
    15661 gacattccaa tcccgtctcg ctttgaccgg acactctctg aatacgagta tgagttgggg
    15721 cgcatactca attgcgctca agcgggatac ctcgcacgag atctagagga ttatgatagg
    15781 gagtaccacc aagcgctcaa gcatggtgga atatcggctg aaaacgattc gttcgagatt
    15841 gattgggaca aagccagcct ctagactata tttcagaaag ggatagtata gaattctccg
    15901 acttccaacc cggcgctgga ttcaatcact gcactgagcg attgccactc ttctcctgac
    15961 tctcttgacg cgtgttgaat atgtgccgtc tattcagcac gctatttctg acaactgtag
    16021 gtcaaggcgt cgatggtagt gataaataca cgctctgcat ttcgcgacgg ttacacaggc
    16081 aattctgaat aaagaaaccg tactactaac tactgataaa tgtattaagt ggaagagagg
    16141 gaattccact acttccggta cccagccagg ccacaaacac caaacgataa ctgaggtact
    16201 tttttacgga taccctgact ggttcctgta tgactctcca gcagattacg acagacgata
    16261 tcgctgactg ggactctctt gacgccattg ccacctcttt tgagaagcgc ggactgaagc
    16321 cgaaaccgga tctcggcgac gacaacgagc ttgtcctcca ggtttccgat cgtgagttta
    16381 tcgttctcgt cgaagcaggc cccggtgaat cggcctcaga tttcaagcca gacgaccgca
    16441 gacgtcgaac gaaccttgtc gccaccaacg actacgagga attcacgttc cttactcgca
    16501 cccgggcact tgacggacaa caacacgggc gtatcaaaca ccagaagctc tcgttcacga
    16561 aagagcaaat gaccagcaag ggtggcgaaa agaacaccat cctccagaaa ctcaacagtc
    16621 tcgaatacga ctcaccagca gcaatctccg acgatctcta cgacaccaag caagtcgtca
    16681 gggagttcta ccaagaattt gaggaactcc gcacctatct cgtgcaggaa gttactggca
    16741 tcccggacga ccgtggtgac gcgaagcaac gctatgtcca gatcaccctc gaccggatga
    16801 tcttccttta cttcatccaa gagaaacgcc ttctcgaccg caacccgaac tatctccacg
    16861 aacaccacga acaacgggca aaaaacggta aagacaccta tgagtcattc tatgagccgc
    16921 tcttcttcga gatgctcgca gaaggtaagc aaaacctcga cttcggctcc cttccgtacc
    16981 tcaatggtgg cctgttctcg aagaacccca tcgaagaaga attcgaagac gcccgactcg
    17041 gcgatacacc cgagcacacc aacgaactgt ttggagacat tcttgacttc ctttcagact
    17101 ggaactggaa cgttgacgag cgactcgaca tcgtcgaccc caagaacctc tcaccagccg
    17161 tccttggtca catcttcgag cagacggtca accagaagga gatgggggcg tactacacgc
    17221 ccgaagagat taccgggttc atgtcccggc ggacgattca tccgtacctc cttgaccagc
    17281 tcaacgaaga agtgggtgcc aaatacgatg agattgacga cgtgttcggg ttccctgctc
    17341 cggacgctga gagtggcgtg gaggcgctcg ccgatggtgg ggtagtcacg gaacaaatcc
    17401 caaccgagaa cgtcgagaca cggcacgtgg agacgctgta tcacgacttc ctaaaggata
    17461 ctcgcgttgt tgaccctgcg gtgggcagcg gcgcattcct acttgcggct caggaagtcc
    17521 tgctggacat ctatatgcaa tgtatcgagt tctttcagca gatggatgac gaggggaaaa
    17581 cgtgggaact ggaggaacgc actgttgagg aactggagcg tatcaatgag ggtcgtggaa
    17641 gcgcttcctt atatgcgaag cggacaatca ttctcaacaa cctgtatggc gtggacattg
    17701 acgatggtgc cgttgaaatc tgtaagctta gattgtggct ctctatggtg gcggatatcg
    17761 aagatgaacc gagtgaagtc gagccattac caaatatcga cttcaatatc cgtcagggga
    17821 actcactaat cggctttact gatatagtcg aacttacaga cgatggagat gcctcactca
    17881 ataattgggg cgctggtgca gggactggag tcaaagagct ctacgaagac gttatcgaag
    17941 cgattgagcg ccaccgtagt gctacgagtg cccaagatgc ggcaaatgca cggcgcgtgg
    18001 cggagtcaaa aatctcctca catagcggag aacttgacga aaaggtgatt gaacagttcc
    18061 acgcagccgg gttagagtca gttgatcagg actctattaa agatttcaat ccgttccact
    18121 gggttctcga atttgctccg gtctatgagg ctggtggttt cgacgtggtg attgggaatc
    18181 ccccatggga tcggattaaa ccactgcggg atgatttctt ctccaaatat gatgagacat
    18241 tccgtacacg tcttccagac gacaaagata gtgtccaaga ggaactgctc tctgacgaag
    18301 agattgcgca ggaatggcag gagtaccaag acgagataga actacgtgct gagtatttca
    18361 agaacacacc agcgtacgat ctacaacggc ctgagattga cggacgaatc aaccctagca
    18421 cgaatgacct ttcatcgttg ttctttgagc gtgtgttcag tttggcagga gacgattctc
    18481 gcgtcgcgca aattcttcca ggcgcaattt tcaatggcgc gtcgggcaaa gatctaagaa
    18541 cacatctgct gaacaacacg caactagatg tactgaacct gtttgagaac cacggcatct
    18601 ttgacggggt tgatgaccgg tatatgtttg gtgtggtggt tttcaagaat gaaggctcta
    18661 cagattatgt ctctggaaga taccaggcag gcgacctctc tatctttgat aacttcggcg
    18721 aaagagcaat ccgaatcccc cgggatgtcc ttgaactcta ttcaccaaaa gcgcgcatct
    18781 tcccccacat cgaatctgaa cgcaaattag aggtgctcaa atccattatc cagaacccgg
    18841 ctatcgctcc ggatgacgct ccaaacgggt acatggaacc gtatcaagga ctccgccgga
    18901 caagtgactc tgatcgtttc gtcgataagt ctgaggcaga gtatcccgta tacggcggga
    18961 agaacatcta ccaatattca tacactcccg aattcatcag tgacgtgcag gaaccggagt
    19021 tctggagcgt tgaggaagaa actgatccct ctcgcagtgc caaacaacgg atgcgagaga
    19081 aaaccgtacg tgacctcaag tccgccatct atgatgcgtt tgagggcacg ggatctcaga
    19141 aggggtttgt caatgaccta ctagaacaac accgtggtaa acctctctca gaaagcgacg
    19201 ttctccttga ttctacagag taccggattg gacttcgccg gatagctcgt tcaaccgacg
    19261 aacggacact catcgccacg gtattgccga aaggcattgt ctgccataat acgttattga
    19321 ctatccccag ctacctgata accccctacg aggagggact gtcggaagaa cccctccaca
    19381 acttctacga gagtatgttc actggcgatg aactgttcgc caaactggga ttgctcaact
    19441 ccattccgtt ggattatcta ctcaggacaa aggtcgatac ggggattgtg atgtacaaat
    19501 tcaaagagtc ccaaatgccc gacctcaccg atggtgacaa ctggttccac tacatttctg
    19561 agcgtgctgc ccgactgagc tgctacggtg aggagtttgc agaaatgcgc gaacgacttg
    19621 gtggtataga gcccgcgact aacactcagg agcgccaaga gatacaggct gagattgatg
    19681 ctgctgcgtt ccatgcatac gggttagaac ggcgggaagt ccagttcatt cttgatgact
    19741 tccatcgggt aacaaatcca cgaatgatga cggagaacta cttcgatatg gtattcgaga
    19801 aattcgacct gttagaggaa gaaggcccct tcaagtaaga tcatcaacga tatcgtccac
    19861 tacaaatggt ttatcacgtt gacgggaaga gggttacagc acttgaccca acaagcttcg
    19921 actctcttga cctgacggaa gcggacattg aggagtggat tatcgagaca ccctcgatac
    19981 ttggtgaaga cctactcgta gtcgcgtcac agtacgcaaa gttcgaccgg gcagcggagc
    20041 gccccgacgt cttggctctc gatccggacg ggaagctcgt ggtaattgag gtgaagcgag
    20101 accgcgcaga caagacgact gatctccaag ccatcaaata cgcgagctac tgttcaacta
    20161 tcagcgccga agagcttcag caggattatc gggcgttctg gaataagcgc cgcgatgaag
    20221 acgaccagct gacgcctgag aaagtgggcg agcggttcac tgaattcctt ggtgaggaca
    20281 tcgtcttgac agaagacggc tacgccgatt tcgtgctgga cgaccggcca cggatcttgt
    20341 tagcagcggg gggcttcggc ccggagatta ccacacccgt tgtctggctc gaacgcgagt
    20401 acggaatgga catcacctgc atcgaactgg atgtacacca acgggacgaa gaggtgtttg
    20461 ttagtgctcg acaggtactc ccgattcccg aggccgaaga gtacatggcc aagcgacgtc
    20521 agaaggagcg acaacagagt cggtcgtcga gtcgagccga gagggcgatc actgtcctac
    20581 ttgaggcggg actcgtcgag gaaggggaca tcgtcctgtt cgatggtgaa agccttccag
    20641 acgacgctga gagagaatat gattcagagg acgacttctg gtgaggccga atcaccggga
    20701 aaacaggacg gagtgacaac gtcgagtggt tggagaacgg tgcagaatac tcgttcactg
    20761 ccctcgccca ggaggtactc gaacaagcga cggatcgcga attcaatgtc aatggctacc
    20821 cgtactggct acacatagag catgacataa gtctctccga actcagacgg tcgaaggttg
    20881 gcgatattga ctggtgaacg tgttgaacta ggggacacca attgaggcac tccccctgag
    20941 aagtattttt ggaacgaaga tacgcctatt ccactggaac ttggtcatat tccagtgtaa
    21001 ctccgtatcg ctgtagggtt atattggctt cctcaagctc cgattctatt ccttcatagt
    21061 catagaagtc ttcagccacc agaaccccct gcaccagttc ctccctttcc gacctgatat
    21121 cttggaggta ttgtttgagt tgtcggacag cgctggggcc cgcggcccct accttagtct
    21181 ccactaccgt tgttactgac tcactcgaca gaaagacgaa atccgcgaac tgttcattct
    21241 ctgtctggta ctccctcttt atatcctcgg aaacgatatt tgcgttgtct tggaacttct
    21301 ctggattatc ccgtaaatgg gcttgaatga cgctttcgtc aaactcaaaa tcatacgact
    21361 ttggctggat tttcggtgca gattgtagct cctcaaccaa tacttctaga ctgtctttct
    21421 ccgcaggatt ccattgctgg agagtgttcg ggagatgcgt cgatgatctc tccttaggct
    21481 ggaacttcgt tgatagctcg tctcgtacta ctggcccgcc gttgtatttc cattcagcaa
    21541 cgtctcgatg gagttggtgt gggaaatcct cgtgaattct ttcgtcttcc cagtcaatgt
    21601 ccccgacctc tgcgactcct cgaattacac tcttgccgcg gattttacgt tgaccgacta
    21661 taatgacgat gtccccctct tccatggggg ttctatcctt gtgctcgtgg cctgcaaagc
    21721 acttcacgac actaaggata tatccgggag attggtcata ctggccctca atactatcaa
    21781 taatgtcact atccggtacc tcctccacaa cttgttttga agctttctcc cacccaacag
    21841 atacgatgtc ttcttgatcc caataaggga agtattcctg gtgacccgac ttaatcaaat
    21901 agcaggttgg cacacctctt tcatttcgcg accacttaat aaaggtatgt gcaagaccgc
    21961 gctggtaaaa ccaacgtcaa agaaaagtgg ttatgagccg ataactcccc aacagatgag
    22021 tcgggcctgg acagcactct ctccaacaag tgtggtctgg tattcttggg acgcttcgat
    22081 gttgtcctcg atgaaagcct ccagttcgtt caagaactcc ttaaccggcc agtcaccgag
    22141 cgacgtgtag tcagggtgtt cccggaaggt ctcccgcaat attcggtctt cgtccgtatt
    22201 cttgagactc acccgatcga actgatcaaa tagcgcatcc gtccactctc cgaccgtatc
    22261 atacctgtcc accggtgcag gttcatcacc gtactgtggc tggattcgca tctgcatcat
    22321 atccaacacc atttcctggg ttgctgactg accaccgcca ctgaacactt cctcaacctg
    22381 cccctctcga accgcttcca accgttcgga gagttgctct tctatcgcct cccggttcgc
    22441 aagaatcctg tcagtgttcc ctgacaggtg ttccccttca gtgtctggtg caatactgag
    22501 tgacccgact gggcgctcct tgatgtcacc actaaacggt ttgtagtaca atgctcgccg
    22561 tacacgccca agcggtgcct cttcgggttc gccagtatcc ttgttctcga accacagatg
    22621 gacgagcccg aacacaccag gacgtgggcc actatcgtgg tcggtggcgt tcgtgtagag
    22681 aaaatcccgg tcatcggtcg gctcactgaa gtacccttcc gcaaattcaa aatcgtcgga
    22741 tgagagtcca tagtcctcgt tcagctcttc tttgaggagc acacgttcga atgccgcgtt
    22801 ctcgtcacta ccagcattcc gcagtaatgg attcttcgag gtgtcgtcca actcgttgta
    22861 gtcgtctacc ttccgagacc ctcggataga agactcaatt tcctcaatct ccagttcacc
    22921 aatggttttc tcagtctcaa cccccgcttt ctccagcact gcatcctcgt ttgggtcgag
    22981 aatattgttc tccttgccga cgatgagcgc gatgtcgttg atcttcgcct gcaagcgctc
    23041 aaggagcttg atcgcagctt cgatgtcgcc atcggggtag aagttgtgga cgtacttgtc
    23101 tgctgtcgag ccgatgcggt cgatgcggcc aacacgctgg acgattcgca tggggttcca
    23161 cggaaggtcg tagttgacga caactgagat gtcctgaagg ttcacaccct cgctcagggt
    23221 gtctgtcgca accacgtact gcaattctgt ttcattactc tcggctagcg tctgctggta
    23281 ccctgacgcc tctggggcga atcgtttgat gatgttttgt ttgttttcgt cacccccttt
    23341 tacgacggca ctattttccg tcgtcatggg tgagttctcg tcgttgacga
//
