GCF_004765785.1 - 9 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

NZ_SBIT01000001.1 (Halorussus ruber)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1.1	terpene	70,022	90,345
Region 1.2	RiPP-like	353,546	365,303

NZ_SBIT01000002.1 (Halorussus ruber)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 2.1	terpene-precursor	363,510	384,352

NZ_ML219768.1 (Halorussus ruber)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 3.1	NI-siderophore	91,143	124,979	Medium	schizokinen	NRPS:Type IV

NZ_SBIT01000008.1 (Halorussus ruber)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 6.1	terpene-precursor	126,089	147,150
Region 6.2	terpene	310,584	331,639

NZ_SBIT01000010.1 (Halorussus ruber)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 8.1	terpene	74,234	95,169
Region 8.2	lanthipeptide-class-ii	155,501	178,683

NZ_SBIT01000015.1 (Halorussus ruber)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 11.1	terpene	16,651	37,604

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1.1	terpene	70,022	90,345
Region 1.2	RiPP-like	353,546	365,303
Region 2.1	terpene-precursor	363,510	384,352
Region 3.1	NI-siderophore	91,143	124,979	Medium	schizokinen	NRPS:Type IV
Region 6.1	terpene-precursor	126,089	147,150
Region 6.2	terpene	310,584	331,639
Region 8.1	terpene	74,234	95,169
Region 8.2	lanthipeptide-class-ii	155,501	178,683
Region 11.1	terpene	16,651	37,604

No secondary metabolite regions were found in these records:: NZ_SBIT01000006.1 (Halorussus ruber); NZ_SBIT01000007.1 (Halorussus ruber); NZ_SBIT01000009.1 (Halorussus ruber); NZ_ML219769.1 (Halorussus ruber); NZ_ML219770.1 (Halorussus ruber); NZ_SBIT01000016.1 (Halorussus ruber); NZ_SBIT01000017.1 (Halorussus ruber); NZ_SBIT01000018.1 (Halorussus ruber); NZ_SBIT01000019.1 (Halorussus ruber); NZ_SBIT01000020.1 (Halorussus ruber); NZ_SBIT01000021.1 (Halorussus ruber); NZ_SBIT01000022.1 (Halorussus ruber); NZ_SBIT01000023.1 (Halorussus ruber); NZ_SBIT01000024.1 (Halorussus ruber); NZ_SBIT01000025.1 (Halorussus ruber); NZ_SBIT01000026.1 (Halorussus ruber); NZ_SBIT01000027.1 (Halorussus ruber); NZ_SBIT01000028.1 (Halorussus ruber); NZ_SBIT01000029.1 (Halorussus ruber); NZ_SBIT01000030.1 (Halorussus ruber); NZ_SBIT01000031.1 (Halorussus ruber); NZ_SBIT01000032.1 (Halorussus ruber)

Compact view

NZ_SBIT01000001.1 - Region 1 - terpene

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Location: 70,022 - 90,345 nt. (total: 20,324 nt) Show pHMM detection rules used

terpene: (PT_phytoene_like or phytoene_synt or Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA or TS_Pyr4)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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resistance

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Isomerases: isomerase

EPL01_RS04975: isochorismate synthase

smcogs: SMCOG1018: isochorismate synthase

Ligases: synthase

EPL01_RS04980: carbamoyl phosphate synthase small subunit

smcogs: SMCOG1249: carbamoyl phosphate synthase small subunit

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001962.3	0.40	PKS	hierridin B, hierridin C	Cyanobium sp. LEGE 06113
BGC0002031.3	0.39	other (other)	kitasetaline	Kitasatospora setae KM-6054
BGC0001778.5	0.32	other (other)	showdomycin	Streptomyces showdoensis
BGC0001634.3	0.32	ribosomal	keywimysin	Streptomyces sp. NRRL F-5702
BGC0001903.3	0.30	other (other)	neocarazostatin A	Streptomyces sp. MA37
BGC0000922.5	0.30	PKS	2-heptyl-3-hydroxy-4-quinolone, 2,4-Quinolinediol, 2-heptylquinolin-4(1H)-one	Pseudomonas aeruginosa PAO1
BGC0002324.3	0.29	NRPS, PKS	myxochelin B, myxochelin N, myxochelin O, myxochelin P, myxochelin Q, myxochelin A	Archangium violaceum
BGC0001529.5	0.29	other (other)	benzastatin J, 7-hydroxyl benzastatin B, 7-hydroxyl O-demethylbenzastatin A, JBIR-67, 7-hydroxyl benzastatin F, 7-hydroxyl O-demethylbenzastatin D, O-demethylvirantmycin, 7-hydroxyl benzastatin D, virantmycin, benzastatin K, methylbenzastatin K	Streptomyces sp. RI18
BGC0002668.2	0.29	ribosomal	cesin A	Clostridium estertheticum
BGC0002439.3	0.29	other (other)	diastaphenazine, izumiphenazine C	Streptomyces diastaticus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001962.3	0.40	PKS	hierridin B, hierridin C	Cyanobium sp. LEGE 06113
BGC0002031.3	0.39	other (other)	kitasetaline	Kitasatospora setae KM-6054
BGC0001778.5	0.32	other (other)	showdomycin	Streptomyces showdoensis
BGC0001634.3	0.32	ribosomal	keywimysin	Streptomyces sp. NRRL F-5702
BGC0001903.3	0.30	other (other)	neocarazostatin A	Streptomyces sp. MA37
BGC0000922.5	0.30	PKS	2-heptyl-3-hydroxy-4-quinolone, 2,4-Quinolinediol, 2-heptylquinolin-4(1H)-one	Pseudomonas aeruginosa PAO1
BGC0002324.3	0.29	NRPS, PKS	myxochelin B, myxochelin N, myxochelin O, myxochelin P, myxochelin Q, myxochelin A	Archangium violaceum
BGC0001529.5	0.29	other (other)	benzastatin J, 7-hydroxyl benzastatin B, 7-hydroxyl O-demethylbenzastatin A, JBIR-67, 7-hydroxyl benzastatin F, 7-hydroxyl O-demethylbenzastatin D, O-demethylvirantmycin, 7-hydroxyl benzastatin D, virantmycin, benzastatin K, methylbenzastatin K	Streptomyces sp. RI18
BGC0002668.2	0.29	ribosomal	cesin A	Clostridium estertheticum
BGC0002439.3	0.29	other (other)	diastaphenazine, izumiphenazine C	Streptomyces diastaticus

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Detailed terpene predictions

Product predictions:

Class	Subclass	Product name	Chain length	Initial cyclisations	Functional groups
tetraterpene	C40 carotenoid		C40	unknown	unknown

Genes with terpene domains:

EPL01_RS04940: Lycopene_cycl

Domain 1 (12 - 92): Lycopene cyclase

Reactions:: C40_carotenoid → C40_carotenoid

Terpene

Glossary

No acronyms to display

NZ_SBIT01000001.1 - Region 2 - RiPP-like

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Location: 353,546 - 365,303 nt. (total: 11,758 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

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Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Hydrolases: phosphatase

EPL01_RS06385: inositol monophosphatase

smcogs: SMCOG1207: inositol monophosphatase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000878.5	0.39	other (other)	puromycin	Streptomyces alboniger
BGC0000249.5	0.29	PKS	nogalamycin	Streptomyces nogalater
BGC0000716.5	0.28	saccharide	spectinomycin	Streptomyces netropsis
BGC0002652.2	0.28	other (other), saccharide	cytosaminomycin F, cytosaminomycin G, streptcytosine P, plicacetin, 40551-F, 12F-plicacetin, streptcytosine D, streptcytosine E	Streptomyces sp. SHP22-7
BGC0000715.5	0.27	saccharide	actinospectacin	Streptomyces spectabilis
BGC0000873.3	0.25	other (other)	A-201A	Saccharothrix mutabilis subsp. capreolus
BGC0000953.5	0.25	saccharide	amicetin	Streptomyces vinaceusdrappus
BGC0002012.4	0.24	PKS	julichrome Q3-3, julichrome Q3-5	Streptomyces afghaniensis 772
BGC0002288.2	0.24	NRPS	ashimide A, ashimide B	Streptomyces sp. NA03103
BGC0001138.5	0.24	other (nucleoside)	a201a	Marinactinospora thermotolerans

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000878.5	0.39	other (other)	puromycin	Streptomyces alboniger
BGC0000249.5	0.29	PKS	nogalamycin	Streptomyces nogalater
BGC0000716.5	0.28	saccharide	spectinomycin	Streptomyces netropsis
BGC0002652.2	0.28	other (other), saccharide	cytosaminomycin F, cytosaminomycin G, streptcytosine P, plicacetin, 40551-F, 12F-plicacetin, streptcytosine D, streptcytosine E	Streptomyces sp. SHP22-7
BGC0000715.5	0.27	saccharide	actinospectacin	Streptomyces spectabilis
BGC0000873.3	0.25	other (other)	A-201A	Saccharothrix mutabilis subsp. capreolus
BGC0000953.5	0.25	saccharide	amicetin	Streptomyces vinaceusdrappus
BGC0002012.4	0.24	PKS	julichrome Q3-3, julichrome Q3-5	Streptomyces afghaniensis 772
BGC0002288.2	0.24	NRPS	ashimide A, ashimide B	Streptomyces sp. NA03103
BGC0001138.5	0.24	other (nucleoside)	a201a	Marinactinospora thermotolerans

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

NZ_SBIT01000002.1 - Region 1 - terpene-precursor

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Location: 363,510 - 384,352 nt. (total: 20,843 nt) Show pHMM detection rules used

terpene-precursor: (PT_FPPS_like and not PT_HPP)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

Gene overview

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MIBiG comparison

KnownClusterBlast

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Terpene

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Transferases: methyltransferase

EPL01_RS09010: methyltransferase

smcogs: SMCOG1089: methyltransferase

Ligases: synthetase

EPL01_RS09045: Polyprenyl synthetase

smcogs: SMCOG1182: Polyprenyl synthetase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002162.3	0.50	terpene	sesterfisherol, sesterfisheric acid, compound 6, compound 7a, compound 5, compound 8	Aspergillus fischeri NRRL 181
BGC0002736.2	0.50	terpene	preaspterpenacid I	Aspergillus terreus NIH2624
BGC0001969.3	0.41	terpene	asperterpenoid A	Talaromyces wortmannii
BGC0000677.5	0.37	terpene	cyclooctatin	Streptomyces melanosporofaciens
BGC0002245.2	0.37	terpene	terpestacin, preterpestacin 3, preterpestacin 2, preterpestacin 1	Bipolaris maydis C5
BGC0000640.3	0.36	terpene	carotenoid	Enterobacteriaceae bacterium DC404
BGC0001528.4	0.36	terpene	betaestacin I, betaestacin II	Phoma betae
BGC0002309.2	0.36	terpene	cattleyene	Streptomyces cattleya NRRL 8057 = DSM 46488
BGC0002219.2	0.36	terpene	(-)-(R)-nephthenol	Stereum hirsutum FP-91666 SS1
BGC0001400.3	0.35	PKS	citreoviridin	Aspergillus terreus NIH2624

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002162.3	0.50	terpene	sesterfisherol, sesterfisheric acid, compound 6, compound 7a, compound 5, compound 8	Aspergillus fischeri NRRL 181
BGC0002736.2	0.50	terpene	preaspterpenacid I	Aspergillus terreus NIH2624
BGC0001969.3	0.41	terpene	asperterpenoid A	Talaromyces wortmannii
BGC0000677.5	0.37	terpene	cyclooctatin	Streptomyces melanosporofaciens
BGC0002245.2	0.37	terpene	terpestacin, preterpestacin 3, preterpestacin 2, preterpestacin 1	Bipolaris maydis C5
BGC0000640.3	0.36	terpene	carotenoid	Enterobacteriaceae bacterium DC404
BGC0001528.4	0.36	terpene	betaestacin I, betaestacin II	Phoma betae
BGC0002309.2	0.36	terpene	cattleyene	Streptomyces cattleya NRRL 8057 = DSM 46488
BGC0002219.2	0.36	terpene	(-)-(R)-nephthenol	Stereum hirsutum FP-91666 SS1
BGC0001400.3	0.35	PKS	citreoviridin	Aspergillus terreus NIH2624

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Detailed terpene predictions

Product predictions:

Class	Product name	Chain length	Initial cyclisations	Functional groups
sesquiterpene precursor	FPP	C15	acyclic	PP
diterpene precursor	GGPP	C20	acyclic	PP
sesterterpene precursor	GFPP	C25	acyclic	PP
triterpene precursor	HPP	C30	acyclic	PP

Genes with terpene domains:

EPL01_RS09045: PT_FPPS_like

Domain 1 (28 - 247): Prenyltransferase; Farnesyl diphosphate synthase like

Subtype: unknown

Reactions:: IPP, DMAPP → FPP; IPP, DMAPP → GGPP; IPP, DMAPP → GFPP; IPP, DMAPP → HPP

Terpene

Glossary

Acronym	Full name
DMAPP	Dimethylallyl diphosphate
FPP	Farnesyl diphosphate
GFPP	Geranylfarnesyl diphosphate
GGPP	Geranylgeranyl diphosphate
HPP	Hexaprenyl diphosphate
IPP	Isopentenyl diphosphate
PP	Diphosphate

NZ_ML219768.1 - Region 1 - NI-siderophore

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Location: 91,143 - 124,979 nt. (total: 33,837 nt) Show pHMM detection rules used

NI-siderophore: IucA_IucC

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

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Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: oxygenase reductase

EPL01_RS00555: lysine/ornithine N-monooxygenase

smcogs: SMCOG1080: lysine/ornithine N-monooxygenase

EPL01_RS00570: alkyl hydroperoxide reductase subunit

smcogs: SMCOG1176: alkyl hydroperoxide reductase subunit

Transferases: aminotransferase

EPL01_RS00535: aminotransferase class-III

smcogs: SMCOG1013: aminotransferase class-III

Hydrolases: deaminase

EPL01_RS00520: ornithine cyclodeaminase

smcogs: SMCOG1158: ornithine cyclodeaminase

Lyases: decarboxylase dehydratase

EPL01_RS00475: NAD-dependent epimerase/dehydratase

smcogs: SMCOG1010: NAD-dependent epimerase/dehydratase

EPL01_RS00540: Decarboxylase, pyridoxal-dependent

smcogs: SMCOG1180: Decarboxylase, pyridoxal-dependent

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002469.2	0.67	other (other)	woodybactin A, woodybactin B, woodybactin C, woodybactin D	Shewanella woodyi ATCC 51908
BGC0002633.2	0.66	other (other)	schizokinen	Leptolyngbya sp. PCC 7376
BGC0002683.2	0.63	NRPS	schizokinen	Nostoc sp. PCC 7120 = FACHB-418
BGC0001572.3	0.62	other (other)	desferrioxamine E	Pantoea agglomerans
BGC0001478.5	0.62	other (other)	desferrioxamine E	Streptomyces sp. ID38640
BGC0002692.2	0.60	other (other)	speibonoxamine, desoxy-desferrioxamine D1, desferrioxamine D1, desferrioxamine B, didesoxy-desferrioxamine D1, desoxy-desferrioxamine B, didesoxy-desferrioxamine B	Kribbella speibonae
BGC0000941.3	0.60	other (other)	desferrioxamin B	Streptomyces griseus subsp. griseus NBRC 13350
BGC0002470.2	0.59	other (other)	synechobactin C9, synechobactin C11, synechobactin 13, synechobactin 14, synechobactin 16, synechobactin A, synechobactin B, synechobactin C	Synechococcus sp. PCC 7002
BGC0002305.2	0.59	other (other)	legonoxamine A, desferrioxamine B, legonoxamine B	Streptomyces sp.
BGC0001713.5	0.58	other (other)	ochrobactin	Ochrobactrum anthropi

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002469.2	0.67	other (other)	woodybactin A, woodybactin B, woodybactin C, woodybactin D	Shewanella woodyi ATCC 51908
BGC0002633.2	0.66	other (other)	schizokinen	Leptolyngbya sp. PCC 7376
BGC0002683.2	0.63	NRPS	schizokinen	Nostoc sp. PCC 7120 = FACHB-418
BGC0001572.3	0.62	other (other)	desferrioxamine E	Pantoea agglomerans
BGC0001478.5	0.62	other (other)	desferrioxamine E	Streptomyces sp. ID38640
BGC0002692.2	0.60	other (other)	speibonoxamine, desoxy-desferrioxamine D1, desferrioxamine D1, desferrioxamine B, didesoxy-desferrioxamine D1, desoxy-desferrioxamine B, didesoxy-desferrioxamine B	Kribbella speibonae
BGC0000941.3	0.60	other (other)	desferrioxamin B	Streptomyces griseus subsp. griseus NBRC 13350
BGC0002470.2	0.59	other (other)	synechobactin C9, synechobactin C11, synechobactin 13, synechobactin 14, synechobactin 16, synechobactin A, synechobactin B, synechobactin C	Synechococcus sp. PCC 7002
BGC0002305.2	0.59	other (other)	legonoxamine A, desferrioxamine B, legonoxamine B	Streptomyces sp.
BGC0001713.5	0.58	other (other)	ochrobactin	Ochrobactrum anthropi

Similar known clusters from MIBiG 4.0

Similar subclusters

No significant matches found.

NZ_SBIT01000008.1 - Region 1 - terpene-precursor

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Location: 126,089 - 147,150 nt. (total: 21,062 nt) Show pHMM detection rules used

terpene-precursor: (PT_FPPS_like and not PT_HPP)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Terpene

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Transferases: acetyltransferase

EPL01_RS13705: acetyl-CoA acetyltransferase

smcogs: SMCOG1124: acetyl-CoA acetyltransferase

Hydrolases: dehalogenase

EPL01_RS13695: haloalkane dehalogenase

smcogs: SMCOG1262: haloalkane dehalogenase

Ligases: ligase synthetase

EPL01_RS13675: Polyprenyl synthetase

smcogs: SMCOG1182: Polyprenyl synthetase

EPL01_RS13715: AMP-dependent synthetase and ligase

smcogs: SMCOG1002: AMP-dependent synthetase and ligase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002274.2	0.56	NRPS	aspulvinone H, aspulvinone B1	Aspergillus terreus NIH2624
BGC0001641.4	0.55	NRPS	kolossin	Photorhabdus laumondii subsp. laumondii TTO1
BGC0000677.5	0.41	terpene	cyclooctatin	Streptomyces melanosporofaciens
BGC0000286.3	0.38	PKS	viguiepinol	Streptomyces sp. KO-3988
BGC0001910.4	0.37	terpene	cyslabdan A, cyslabdan B, cyslabdan C	Streptomyces cyslabdanicus
BGC0000639.3	0.37	terpene	carotenoid	Enterobacteriaceae bacterium DC260
BGC0000642.3	0.37	terpene	carotenoid	Enterobacteriaceae bacterium DC413
BGC0001911.3	0.37	terpene	raimonol	Streptomyces anulatus
BGC0002309.2	0.36	terpene	cattleyene	Streptomyces cattleya NRRL 8057 = DSM 46488
BGC0002007.2	0.36	terpene	atolypene A, atolypene B	Amycolatopsis tolypomycina

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002274.2	0.56	NRPS	aspulvinone H, aspulvinone B1	Aspergillus terreus NIH2624
BGC0001641.4	0.55	NRPS	kolossin	Photorhabdus laumondii subsp. laumondii TTO1
BGC0000677.5	0.41	terpene	cyclooctatin	Streptomyces melanosporofaciens
BGC0000286.3	0.38	PKS	viguiepinol	Streptomyces sp. KO-3988
BGC0001910.4	0.37	terpene	cyslabdan A, cyslabdan B, cyslabdan C	Streptomyces cyslabdanicus
BGC0000639.3	0.37	terpene	carotenoid	Enterobacteriaceae bacterium DC260
BGC0000642.3	0.37	terpene	carotenoid	Enterobacteriaceae bacterium DC413
BGC0001911.3	0.37	terpene	raimonol	Streptomyces anulatus
BGC0002309.2	0.36	terpene	cattleyene	Streptomyces cattleya NRRL 8057 = DSM 46488
BGC0002007.2	0.36	terpene	atolypene A, atolypene B	Amycolatopsis tolypomycina

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Detailed terpene predictions

Product predictions:

Class	Product name	Chain length	Initial cyclisations	Functional groups
sesquiterpene precursor	FPP	C15	acyclic	PP
diterpene precursor	GGPP	C20	acyclic	PP
sesterterpene precursor	GFPP	C25	acyclic	PP
triterpene precursor	HPP	C30	acyclic	PP

Genes with terpene domains:

EPL01_RS13675: PT_FPPS_like

Domain 1 (40 - 352): Prenyltransferase; Farnesyl diphosphate synthase like

Subtype: unknown

Reactions:: IPP, DMAPP → FPP; IPP, DMAPP → GGPP; IPP, DMAPP → GFPP; IPP, DMAPP → HPP

Terpene

Glossary

Acronym	Full name
DMAPP	Dimethylallyl diphosphate
FPP	Farnesyl diphosphate
GFPP	Geranylfarnesyl diphosphate
GGPP	Geranylgeranyl diphosphate
HPP	Hexaprenyl diphosphate
IPP	Isopentenyl diphosphate
PP	Diphosphate

NZ_SBIT01000008.1 - Region 2 - terpene

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Location: 310,584 - 331,639 nt. (total: 21,056 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (PT_phytoene_like or phytoene_synt or Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA or TS_Pyr4)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Terpene

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: dehydrogenase oxidoreductase

EPL01_RS14580: acyl-CoA dehydrogenase

smcogs: SMCOG1006: acyl-CoA dehydrogenase

EPL01_RS14610: 3-hydroxybutyryl-CoA dehydrogenase

smcogs: SMCOG1095: 3-hydroxybutyryl-CoA dehydrogenase

EPL01_RS14655: oxidoreductase

smcogs: SMCOG1079: oxidoreductase

Transferases: methyltransferase

EPL01_RS14550: methyltransferase

smcogs: SMCOG1089: methyltransferase

Hydrolases: hydrolase

EPL01_RS14620: isochorismatase

smcogs: SMCOG1027: isochorismatase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000278.3	0.45	PKS	urdamycin	Streptomyces fradiae
BGC0000706.3	0.45	saccharide	kanamycin	Streptomyces kanamyceticus
BGC0002284.3	0.44	other (other)	corynecin III, corynecin I, corynecin II	Rhodococcus sp. H-CA8f
BGC0001778.5	0.41	other (other)	showdomycin	Streptomyces showdoensis
BGC0000207.5	0.40	PKS	chartreusin	Streptomyces chartreusis
BGC0000003.3	0.39	PKS	AF-toxin	Alternaria alternata
BGC0000720.3	0.38	saccharide	tobramycin	Streptoalloteichus tenebrarius
BGC0002412.2	0.38	NRPS	holomycin	Photobacterium galatheae
BGC0002091.3	0.37	NRPS	holomycin	Yersinia ruckeri ATCC 29473
BGC0001464.3	0.35	other (other)	tetrabromopyrrole	Pseudoalteromonas sp. PS5

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000278.3	0.45	PKS	urdamycin	Streptomyces fradiae
BGC0000706.3	0.45	saccharide	kanamycin	Streptomyces kanamyceticus
BGC0002284.3	0.44	other (other)	corynecin III, corynecin I, corynecin II	Rhodococcus sp. H-CA8f
BGC0001778.5	0.41	other (other)	showdomycin	Streptomyces showdoensis
BGC0000207.5	0.40	PKS	chartreusin	Streptomyces chartreusis
BGC0000003.3	0.39	PKS	AF-toxin	Alternaria alternata
BGC0000720.3	0.38	saccharide	tobramycin	Streptoalloteichus tenebrarius
BGC0002412.2	0.38	NRPS	holomycin	Photobacterium galatheae
BGC0002091.3	0.37	NRPS	holomycin	Yersinia ruckeri ATCC 29473
BGC0001464.3	0.35	other (other)	tetrabromopyrrole	Pseudoalteromonas sp. PS5

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Detailed terpene predictions

Product predictions:

Class	Subclass	Product name	Chain length	Initial cyclisations	Functional groups
triterpene		squalene	C30	acyclic	none
triterpene	C30 carotenoid	diapophytoene	C30	acyclic	none
triterpene		PSPP	C30	acyclic	PP
tetraterpene	C40 carotenoid	phytoene	C40	acyclic	none
triterpene		hydroxysqualene	C30	acyclic	OH

Genes with terpene domains:

EPL01_RS14600: PT_phytoene_like

Domain 1 (26 - 282): Prenyltransferase; Phytoene synthase like

Subtype: unknown

Reactions:: FPP → squalene; FPP → diapophytoene; FPP → PSPP; GGPP → phytoene; PSPP → hydroxysqualene

Terpene

Glossary

Acronym	Full name
FPP	Farnesyl diphosphate
GGPP	Geranylgeranyl diphosphate
PP	Diphosphate
PSPP	Presqualene diphosphate

NZ_SBIT01000010.1 - Region 1 - terpene

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Location: 74,234 - 95,169 nt. (total: 20,936 nt) Show pHMM detection rules used

terpene: (PT_phytoene_like or phytoene_synt or Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA or TS_Pyr4)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Terpene

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: dehydrogenase

EPL01_RS16650: alcohol dehydrogenase

smcogs: SMCOG1040: alcohol dehydrogenase

Transferases: glycosyltransferase

EPL01_RS16640: glycosyl transferase group 1

smcogs: SMCOG1045: glycosyl transferase group 1

Hydrolases: hydrolase

EPL01_RS16630: metallo-beta-lactamase family protein

smcogs: SMCOG1170: metallo-beta-lactamase family protein

Similar gene clusters

Analysis type:

Reference	terpene	Similarity score	Type	Compound(s)	Organism
BGC0000236.5		0.28	PKS	kinamycin	Streptomyces murayamaensis

Reference	Aggregated	Similarity score	Type	Compound(s)	Organism
BGC0000236.5		0.28	PKS	kinamycin	Streptomyces murayamaensis

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Detailed terpene predictions

Product predictions:

Class	Subclass	Product name	Chain length	Initial cyclisations	Functional groups
tetraterpene	C40 carotenoid		C40	unknown	unknown

Genes with terpene domains:

EPL01_RS16670: Lycopene_cycl + Lycopene_cycl

Domain 1 (6 - 97): Lycopene cyclase

Reactions:: C40_carotenoid → C40_carotenoid

Domain 2 (152 - 240): Lycopene cyclase

Reactions:: C40_carotenoid → C40_carotenoid

Terpene

Glossary

No acronyms to display

NZ_SBIT01000010.1 - Region 2 - lanthipeptide-class-ii

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Location: 155,501 - 178,683 nt. (total: 23,183 nt) Show pHMM detection rules used

lanthipeptide-class-ii: cds(LANC_like and DUF4135)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Lanthipeptides

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Transferases: methyltransferase

EPL01_RS17105: methyltransferase

smcogs: SMCOG1089: methyltransferase

Lyases: cyclase

EPL01_RS17120: lanthionine synthetase C family protein

smcogs: SMCOG1070: lanthionine synthetase C family protein

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002703.2	0.52	ribosomal	archalan α	Halorussus salinus
BGC0000554.4	0.48	ribosomal	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0002704.2	0.47	ribosomal	archalan β	Halorussus salinus
BGC0001579.4	0.46	ribosomal	duramycin	Streptomyces cinnamoneus
BGC0000503.5	0.45	ribosomal	cinnamycin	Streptomyces cinnamoneus
BGC0001787.3	0.43	ribosomal	suicin 3908	Streptococcus suis
BGC0000516.4	0.42	ribosomal	geobacillin II	Geobacillus thermodenitrificans
BGC0000547.5	0.42	ribosomal	salivaricin 9	Streptococcus salivarius
BGC0002699.2	0.41	ribosomal	nostolysamide A, nostolysamide B	Nostoc punctiforme PCC 73102
BGC0000498.5	0.41	ribosomal	bovicin HJ50	Streptococcus equinus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002703.2	0.52	ribosomal	archalan α	Halorussus salinus
BGC0000554.4	0.48	ribosomal	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0002704.2	0.47	ribosomal	archalan β	Halorussus salinus
BGC0001579.4	0.46	ribosomal	duramycin	Streptomyces cinnamoneus
BGC0000503.5	0.45	ribosomal	cinnamycin	Streptomyces cinnamoneus
BGC0001787.3	0.43	ribosomal	suicin 3908	Streptococcus suis
BGC0000516.4	0.42	ribosomal	geobacillin II	Geobacillus thermodenitrificans
BGC0000547.5	0.42	ribosomal	salivaricin 9	Streptococcus salivarius
BGC0002699.2	0.41	ribosomal	nostolysamide A, nostolysamide B	Nostoc punctiforme PCC 73102
BGC0000498.5	0.41	ribosomal	bovicin HJ50	Streptococcus equinus

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Lanthipeptide predictions

Lanthipeptide(s) for EPL01_RS17120

EPL01_RS21830

Leader:

MSVLDTDNAA

Core:

ESAKQSYDAEFDAVDTGSRDSPDGMKGEECAWSCASSTLC

Core with dehydrations:

EDhaAKQDhaYDAEFDAVDDhbGDhaRDDhaPDGMKGEECysAWDhaCysADhaDhaDhbLCys

antiSMASH-DB 4.0 matches for EPL01_RS21830

100.0%

NZ_SBIT01000010.1:

Lanthipeptides: EPL01_RS21830_lanthipeptide

1

ESAKQSYDAEFDAVDTGSRDSPDGMKGEECAWSCASSTLC

40

ESAKQSYDAEFDAVDTGSRDSPDGMKGEECAWSCASSTLC

1

ESAKQSYDAEFDAVDTGSRDSPDGMKGEECAWSCASSTLC

40

28.3%

NZ_AKXV01000031.1and 1 other:

NZ_AKXV01000031.1 Lanthipeptides: Y19_RS44045_lanthipeptide

Lanthipeptides: Y19_RS44045_lanthipeptide

7

YDAEFDAVDTGSRDSPDGMKGEECAWSCASST

38

YD EF+ V+ G D G WSCA T

1

YD-EFELVEMGEADVYGGTT-----WSCAIVT

26

allorf_176054_176206

Leader:

MRVNPRMRFNIFESTFYYG

Core:

CECQRRSFSDELGRKPRPWKQIRFCMHNVYA

Core with dehydrations:

CysECysQRRDhaFDhaDELGRKPRPWKQIRFCysMHNVYA

antiSMASH-DB 4.0 matches for allorf_176054_176206

100.0%

NZ_SBIT01000010.1:

Lanthipeptides: allorf_176054_176206_lanthipeptide

1

CECQRRSFSDELGRKPRPWKQIRFCMHNVYA

31

CECQRRSFSDELGRKPRPWKQIRFCMHNVYA

1

CECQRRSFSDELGRKPRPWKQIRFCMHNVYA

31

22.6%

NZ_LN831278.1:

Lanthipeptides: allorf_496552_496677_lanthipeptide

17

RPWKQIRFC-MHN

28

R WK ++FC +HN

9

RVWKILQFCVVHN

21

13.1%

NZ_QTVL01000002.1and 2 others:

NZ_QTZB01000015.1 Lanthipeptides: DXC15_RS14275_lanthipeptideNZ_QUKU01000003.1 Lanthipeptides: DXC27_RS03000_lanthipeptide

Lanthipeptides: DWZ44_RS04090_lanthipeptide

1

CECQRRSFSDELGR

14

EC RR + DE GR

21

SEC-RREYKDEFGR

33

with 5 more sequence matches

12.9%

NZ_CP065430.1and 1 other:

NZ_MRXY01000010.1 Lanthipeptides: allorf_005966_006160_lanthipeptide

Lanthipeptides: allorf_1209205_1209336_lanthipeptide

21

QIRFCMHNV

29

++R+C+HN+

3

ELRYCVHNI

11

10.9%

NZ_JALAPU010000003.1and 1 other:

NZ_JALAUG010000006.1 Lanthipeptides: MOE44_RS16960_lanthipeptide

Lanthipeptides: MOD17_RS07975_lanthipeptide

3

CQRRSFSDELGRKPRPWKQIRFCMHNV

29

+++ F + + R+P+ +K C+ +

17

LEQQGFVELVSRRPKAYKISEDCLEEI

43

10.9%

NZ_JALATU010000001.1:

Lanthipeptides: allorf_0125951_0126130_lanthipeptide

3

CQRRSFSDELGRKPRPWKQIRFCMHNV

29

+++ F + + R+P+ +K C+ +

17

LEQKGFVELVSRRPKAYKISEDCLEAI

43

10.9%

NZ_JALAVR010000001.1:

Lanthipeptides: MOE47_RS04580_lanthipeptide

3

CQRRSFSDELGRKPRPWKQIRFCMHNV

29

+++ F + + R+P+ +K C+ +

17

LEQKGFVELVSRRPKAYKISEDCLEEI

43

7.4%

NZ_FMXV01000022.1:

Lanthipeptides: allorf_002190_002423_lanthipeptide

19

WKQIRFCMH

27

W +R CMH

30

WGGLRMCMH

38

MIBiG 4.0 matches for allorf_176054_176206

22.6%

BGC0000517.4 (BAB04173.1):

Lanthipeptide: haloduracin β or haloduracin α

3

CQRRSFSDELGRKPRPWKQIRFCM

26

C + S LG K CM

1

CAWYNISCRLGNKGAYCTLTVECM

24

allorf_176079_176204

Leader:

MRIHCAYRTVFVSMAVAFGPVHRRMSAAG

Core:

TRSRNKRWIRRC

Core with dehydrations:

DhbRDhaRNKRWIRRCys

antiSMASH-DB 4.0 matches for allorf_176079_176204

100.0%

NZ_SBIT01000010.1:

Lanthipeptides: allorf_176079_176204_lanthipeptide

1

TRSRNKRWIRRC

12

TRSRNKRWIRRC

1

TRSRNKRWIRRC

12

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Lanthipeptides

Core peptide predictions

EPL01_RS21830 - Class II

Cleavage pHMM score: -7.20

RODEO score: 0

Monoisotopic mass: 4070.7 Da

Molecular weight: 4073.3 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 4091.3 Da N = 1; 4109.3 Da N = 2; 4127.3 Da N = 3; 4145.3 Da N = 4; 4163.4 Da N = 5; 4181.4 Da N = 6

allorf_176054_176206 - Class II

Cleavage pHMM score: -6.10

RODEO score: 0

Monoisotopic mass: 3803.8 Da

Molecular weight: 3806.4 Da

Number of bridges: 2

allorf_176079_176204 - Class II

Cleavage pHMM score: -4.30

RODEO score: 0

Monoisotopic mass: 1594.9 Da

Molecular weight: 1595.9 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 1613.9 Da N = 1

NZ_SBIT01000015.1 - Region 1 - terpene

Download region GenBank file

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Location: 16,651 - 37,604 nt. (total: 20,954 nt) Show pHMM detection rules used

terpene: (PT_phytoene_like or phytoene_synt or Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA or TS_Pyr4)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Terpene

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: dehydrogenase

EPL01_RS17670: dehydrogenase

smcogs: SMCOG1222: dehydrogenase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000637.3	0.45	terpene	carotenoid	Corynebacterium glutamicum
BGC0000644.3	0.45	terpene	carotenoid	Dietzia sp. CQ4
BGC0000650.3	0.44	terpene	carotenoid	Algoriphagus sp. KK10202C
BGC0000664.5	0.42	terpene	isorenieratene	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000633.3	0.42	terpene	carotenoid	Streptomyces avermitilis
BGC0001227.3	0.42	terpene	isorenieratene	Streptomyces collinus Tu 365
BGC0000513.3	0.41	ribosomal	Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3	Saccharopolyspora erythraea NRRL 2338
BGC0001456.3	0.41	terpene	isorenieratene	Streptomyces argillaceus
BGC0000551.5	0.41	ribosomal	SapB	Streptomyces coelicolor A3(2)
BGC0000504.5	0.40	ribosomal	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000637.3	0.45	terpene	carotenoid	Corynebacterium glutamicum
BGC0000644.3	0.45	terpene	carotenoid	Dietzia sp. CQ4
BGC0000650.3	0.44	terpene	carotenoid	Algoriphagus sp. KK10202C
BGC0000664.5	0.42	terpene	isorenieratene	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000633.3	0.42	terpene	carotenoid	Streptomyces avermitilis
BGC0001227.3	0.42	terpene	isorenieratene	Streptomyces collinus Tu 365
BGC0000513.3	0.41	ribosomal	Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3	Saccharopolyspora erythraea NRRL 2338
BGC0001456.3	0.41	terpene	isorenieratene	Streptomyces argillaceus
BGC0000551.5	0.41	ribosomal	SapB	Streptomyces coelicolor A3(2)
BGC0000504.5	0.40	ribosomal	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Detailed terpene predictions

Product predictions:

Class	Subclass	Product name	Chain length	Initial cyclisations	Functional groups
triterpene		PSPP	C30	acyclic	PP
triterpene	C30 carotenoid	diapophytoene	C30	acyclic	none
triterpene		squalene	C30	acyclic	none
tetraterpene	C40 carotenoid	phytoene	C40	acyclic	none
triterpene		hydroxysqualene	C30	acyclic	OH

Genes with terpene domains:

EPL01_RS17685: PT_phytoene_like

Domain 1 (8 - 278): Prenyltransferase; Phytoene synthase like

Subtype: unknown

Reactions:: FPP → PSPP; FPP → diapophytoene; FPP → squalene; GGPP → phytoene; PSPP → hydroxysqualene

Terpene

Glossary

Acronym	Full name
FPP	Farnesyl diphosphate
GGPP	Geranylgeranyl diphosphate
PP	Diphosphate
PSPP	Presqualene diphosphate