LOCUS       NZ_SBIT01000015        20954 bp    DNA     linear   CON 23-OCT-2024
DEFINITION  Halorussus ruber strain YC25 Scaffold11_1, whole genome shotgun
            sequence.
ACCESSION   NZ_SBIT01000015
VERSION     NZ_SBIT01000015.1
KEYWORDS    WGS; RefSeq.
SOURCE      Halorussus ruber
  ORGANISM  Halorussus ruber
            Archaea; Methanobacteriati; Methanobacteriota; Stenosarchaea group;
            Halobacteria; Halobacteriales; Haladaptataceae; Halorussus.
REFERENCE   1  (bases 1 to 188656)
  AUTHORS   Cui,H.-L.
  TITLE     Genome sequence of Halorussus ruber YC25, isolated from an inland
            salt lake of China
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 188656)
  AUTHORS   Cui,H.-L.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-JAN-2019) School of Food & Biological Engineering,
            Jiangsu University, 301 Xuefu Road, Jingkou District, Zhenjiang,
            Jiangsu 212013, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. Dec-2018
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004765785.1-RS_2024_10_23
            Annotation Date                   :: 10/23/2024 04:20:59
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,396
            CDSs (total)                      :: 4,336
            Genes (coding)                    :: 4,270
            CDSs (with protein)               :: 4,270
            Genes (RNA)                       :: 60
            rRNAs                             :: 3, 3, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1 (5S, 23S)
            partial rRNAs                     :: 3 (16S)
            tRNAs                             :: 51
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 66
            CDSs (without protein)            :: 66
            Pseudo Genes (ambiguous residues) :: 0 of 66
            Pseudo Genes (frameshifted)       :: 18 of 66
            Pseudo Genes (incomplete)         :: 50 of 66
            Pseudo Genes (internal stop)      :: 6 of 66
            Pseudo Genes (multiple problems)  :: 7 of 66
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:04:38
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 16650
            Orig. end                         :: 37604
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            SBIT01000015.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20954
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20954
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20954
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10954](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10954)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(79..1098)
                     /locus_tag="EPL01_RS17630"
     CDS             complement(79..1098)
                     /EC_number="3.4.23.-"
                     /GO_function="GO:0042500 - aspartic endopeptidase activity,
                     intramembrane cleaving [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008014408.1"
                     /locus_tag="EPL01_RS17630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="presenilin family intramembrane aspartyl protease
                     PSH"
                     /protein_id="WP_135826604.1"
                     /transl_table=11
                     /translation="MENRTRAFAAVGLTVLMFLLVQLGALALVEPFQQAGYQQVENPSD
                     PTNSLVYVGAVLVLTGVMLLIIKLDVQWLLRGAIIFTSGLLSWYVFSVVIPGWLVVSFG
                     GAPLNVVALAAAGLVSLALAVHPEWYVIDAAGVLMGAGAAGLFGISFGLLPAILLLSVL
                     AIYDAISVYGTEHMLTLASGVMDLKIPVILVIPLSLSYSFLDDEGMAAEDEESPEEGTA
                     SAADGGEPSETDAEAERPGMGERDVFFIGLGDAVMPTVMVASAAFFAPAEPLISGLALN
                     LPALTSMVGTIAGLLVLLWMVMKGRAHAGLPLLNGGAIGGYLVGALASGMTLVQALGF"
     gene            1206..1523
                     /locus_tag="EPL01_RS17635"
     CDS             1206..1523
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012944358.1"
                     /locus_tag="EPL01_RS17635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_135826605.1"
                     /transl_table=11
                     /translation="MSTHGTRGASPESARLPDAVPFGLPALSRLSWELGSRVVADAPLL
                     TEWEHVTSGRTLEVHDVTDNTVVLGVRTPVGRERFFGAAKEDFEEKRPLLSDADDWRRP
                     E"
     gene            complement(1538..1765)
                     /locus_tag="EPL01_RS17640"
     CDS             complement(1538..1765)
                     /GO_component="GO:0031429 - box H/ACA snoRNP complex
                     [Evidence IEA]"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0034513 - box H/ACA snoRNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0000454 - snoRNA guided rRNA pseudouridine
                     synthesis [Evidence IEA]"
                     /GO_process="GO:0031120 - snRNA pseudouridine synthesis
                     [Evidence IEA]"
                     /GO_process="GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004977496.1"
                     /locus_tag="EPL01_RS17640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="H/ACA ribonucleoprotein complex subunit GAR1"
                     /protein_id="WP_135826606.1"
                     /transl_table=11
                     /translation="MQRVGEVVRTAQGLAVVRCADDDHPDVGTEAVDEQLNSVGRVVDV
                     FGPVSRPYVAVTPDEGVTLATLLGQKLYAR"
     gene            complement(1778..2059)
                     /gene="srp19"
                     /locus_tag="EPL01_RS17645"
     CDS             complement(1778..2059)
                     /GO_function="GO:0008312 - 7S RNA binding [Evidence IEA]"
                     /GO_process="GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA]"
                     /codon_start=1
                     /gene="srp19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006067537.1"
                     /locus_tag="EPL01_RS17645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="signal recognition particle subunit SRP19"
                     /protein_id="WP_135826607.1"
                     /transl_table=11
                     /translation="MVEKVLWPAYFDAEKTRNEGRRVAEEMAVEEPTVDEIAQAVQQVG
                     YDAIIERDKAYSRENWQENGRVLVQNADDSTKNDLIQAVAAYVAALRK"
     gene            complement(2138..3274)
                     /locus_tag="EPL01_RS17650"
     CDS             complement(2138..3274)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1033: iron
                     compound ABC transporter, periplasmic"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009366137.1"
                     /locus_tag="EPL01_RS17650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PGF-CTERM-anchored ABC transporter
                     substrate-binding protein"
                     /protein_id="WP_135826608.1"
                     /transl_table=11
                     /translation="MRQKVTSVFAVLLLLAAGVAPVGAVTGGTADAAQSSCSFPVTSTD
                     ATGTEVTVEQKPERVVTLSPSAAQTMWEIGGKSQVVGVSQYAAYLDGTDSLTNVSGSGQ
                     QFVNVEKVVSTEPDLVLAPNVIPNETVQKLREAGLTVYKFDFATSVEDIYAKTELMGQL
                     TGNCEGATETVSWMKDRVGTVREAVENSERSTVFISQGAGWTAGGGTFIDNVVELAGGT
                     NVAAEANISGYGKISEEVIVEQNPEWIVQLGAFGAYPETEAYNGTDAVKQGNVITVSNE
                     NISQPAPRVVYAITKMAKAFHPDAYAEANATTTEATETTVEPTTTESPETTTDEGAMQE
                     QEETTTATADGSSGSTPGFGVTAAVAALAGAALLARRR"
     gene            3336..4436
                     /gene="btuC"
                     /locus_tag="EPL01_RS17655"
     CDS             3336..4436
                     /codon_start=1
                     /gene="btuC"
                     /gene_functions="transport (smcogs) SMCOG1011: transport
                     system permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014039571.1"
                     /locus_tag="EPL01_RS17655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="vitamin B12 ABC transporter permease BtuC"
                     /protein_id="WP_135826609.1"
                     /transl_table=11
                     /translation="MADSARVVGWSIGLLAALAAVVVVSAAIGPVSLEYLVVGKVLLNA
                     LAVPAGVGLAERTLRIAGLAVTVPGPTVEFAPVFHFAVPETARTIVVTLRLPRIALGAV
                     VGFALSTAGVVMQGFFRNPMADPSIIGVSSGAAVGAVATIAIPFAVPLALPTAAFVGAV
                     LAAFGVYLLATEEGRTPVATLLLAGVAVQTFLGAVVSFLLLQSGESLRRAVYWLMGHLH
                     LASWEDVTFVLPVAILGFAVLLAYARDLNVLLLGEEDAHALGVEVERTKRLLLAVASVM
                     TGAAVAVSGVIGFVGLVVPHVMRLLVGPDHRILLPTSALAGATFLVATDTVARSGTAEL
                     PVGIVTAFLGAPFFLYLLRTREVHAL"
     gene            4984..6255
                     /locus_tag="EPL01_RS17660"
     CDS             4984..6255
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009366139.1"
                     /locus_tag="EPL01_RS17660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="heme ABC transporter ATP-binding protein"
                     /protein_id="WP_135826610.1"
                     /transl_table=11
                     /translation="MIRIQDLEVELGGTEILDGVTTEIEDGQFVGLVGPNGAGKTTLLR
                     AINGVLKPDSGSVYVDSDPVADLSSKEASRRIAVVPQDTSLSFDFPVEEVVAMGRHPYR
                     SRFSGPKPSTDGDSDQQIVEEAMARTEVQHLAERSITAVSGGERQRVLLARALAQDTPA
                     LLLDEPTASLDINHQVRTLELVRELADEGKTVVAAIHDLNLAAHYCDELRLLAGGEIRA
                     SGDPADVLAEDHLEAAFDTRAVVSSHPVTGSTYVTALPERPDDAAGRVHVVGGGGTVSR
                     LLYLLSAAGYDVSVGVLNEGDSDLETARSLGLDAVTEEPFAPVGEAARREAEERIREAD
                     ATILADVEVGAGNVANLRAAREADSVVVVEERPFAERNFAGSDAAALYRELCERGQVVG
                     PDELLSAVERAVGEKRASARCDAT"
     gene            complement(6263..6571)
                     /locus_tag="EPL01_RS17665"
     CDS             complement(6263..6571)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007978553.1"
                     /locus_tag="EPL01_RS17665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_135826611.1"
                     /transl_table=11
                     /translation="MNPAKFALLLGVGLLSFLFVVSLYVVWTRIVGLDPTLAQRCASFS
                     RPARMAIALLSGGVLGTASMAAPSVDVGIAGMVLLAASTFAALMLFELLQQRQRVAS"
     gene            6716..8248
                     /locus_tag="EPL01_RS17670"
     CDS             6716..8248
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006179807.1"
                     /locus_tag="EPL01_RS17670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_135826612.1"
                     /sec_met_domain="DAO (E-value: 1.7e-10, bitscore: 34.7,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQLSDRSVAVVGSGFGGLSTACYLADAGADVTVVEKNEQLGGRAS
                     VLERDGFRFDMGPSWYLMPDVFERFFGHFGRSPSEYYELEHLHPHYKIFFKDGDRVTVT
                     ADREETKATFEEYERGAGPALDAYLEEAEETYQIGMEHFVYTDRPRFRDYVDWDVVRHA
                     RGLTFLGSMQDHVADYFDHPKLRQIMQYTLVFLGGSPKNTPALYNLMSHVDFNLGVHYP
                     RAKDGTATDGGDADGTTPGGMGVVVDAIAEMGEELGVEYRTGSEVESILGSAGNFRVET
                     EDGFLRADLVVSDADYAHTEQELLPPQSRQYDADYWESRTYAPSAFLLYLGVEGDVDGL
                     EHHTLVLPTEWNDHFDEIFEEPAWPEDPAYYLCVPSETDDTVAPEGHSNLFALVPIAPG
                     LDDGPETRRRYRDFVLDDIAENTGVDLRDRIVLEESFCVSDFAERYNSIQGTALGLAHT
                     LRQTGPLRPGHRSSEVPGLYFTGSFTTPGIGVPMCLISGQHTADALLEDYGE"
     gene            8253..9134
                     /locus_tag="EPL01_RS17675"
     CDS             8253..9134
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ubiA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018128652.1"
                     /locus_tag="EPL01_RS17675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="prenyltransferase"
                     /protein_id="WP_135826613.1"
                     /sec_met_domain="ubiA (E-value: 1.1e-15, bitscore: 51.4,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLRYLLKLSRPRFWLYLAGPVLVGVAYGASAPSDLFAPAGVALFA
                     YFLLPANVYLYGINDVFDADIDEENPKKTGEEAPEARFRGGTAVTLLVALCGLAGFALA
                     GAFAVGALALGSNPPMGATVGVAVWVVAFLLLGYAYSAPPFRLKTVPPLDSVSNGLYVL
                     PGAAAYVALAGRQPPALAVVSGWLWAMAMHTFSAIPDIEPDRRAGIRTTATVLGERRTL
                     AYCGVCWLLAAGAFGLLDIRAGALLLLYPLFALGVAETDVSVSRAYWWFPAINTLVGMV
                     LTLGGLWGVVRG"
     gene            9136..9957
                     /gene="cruF"
                     /locus_tag="EPL01_RS17680"
     CDS             9136..9957
                     /EC_number="4.2.1.161"
                     /GO_function="GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cruF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007741202.1"
                     /locus_tag="EPL01_RS17680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="bisanhydrobacterioruberin hydratase"
                     /protein_id="WP_135826767.1"
                     /transl_table=11
                     /translation="MSRTQVERRLSDLVRENRFTIAVVFPLVGAGMFVASHEGWLPPWL
                     AMNPLLVLFGTLVMRLPLVAGLAPLVDRRAGVGLLLVTAYSYVIEYIGVHYGVPYGEFS
                     YQIELGPMVGGVPVGLPVFFLPLVVNSYLLVLLLLPKAGRIARTLAALAVVLVVDFVLD
                     PAAVGLGFWDYGGGFYYGVPFSNFQGWILSGLIAVSLVEWGFDRAALGDRLRNCEFALD
                     DFVSFVLLWGAMNVYFGNWIAVALAAGLSAGLVRTDRFDFVGIGRERPEQG"
     gene            complement(10001..10954)
                     /locus_tag="EPL01_RS17685"
     CDS             complement(10001..10954)
                     /EC_number="2.5.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009760707.1"
                     /locus_tag="EPL01_RS17685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_135826614.1"
                     /sec_met_domain="phytoene_synt (E-value: 1.8e-66, bitscore:
                     217.8, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.8e-57,
                     bitscore: 188.5, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVTDRQLRRSKTIQQRTGRTFHFATRLLPRRIRNPTYVLYAFFRV
                     ADEVVDGADDLPPDEQRARLEQLRAEALGEVETDDEVLAAFQEVSDERGIPDEEIEIFI
                     DAMISDIEKSRWETYAELEEYMRGSASAVGVMMQSVMGVEKPERAKPHAVALGEAFQLT
                     NFLRDVREDILDHDRIYLPGTTRERHGVTEADIRRCNPTDGFRAAMADELRRAERKYRE
                     GVAGIEYLPEDCQFAVLYAAVLYAEHHRLIRARDYDVFSSEPEVGAFRAAWLWAKTRWY
                     WQKSRDPVTVFRAVSAVPEAEKVHASHRPEGAPQAD"
     gene            11186..11842
                     /locus_tag="EPL01_RS17690"
     CDS             11186..11842
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EPL01_RS17690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_135826615.1"
                     /transl_table=11
                     /translation="MSSSDAVTETLDEGGNGIAGRVGSLAKPLGPALAKHAESGTLAAA
                     SGVVSLVRAGRTFLKGNRKRGVLQALGGLFWVGVALAQRRTGRGSTAGATRGGPSTSDL
                     ADVADSSPDIEDVETEGTDADHATGEEVVDTTDADIEESDTAPEVESHAEGDVDQRDVV
                     ESGDLEDADADEESEAGSEDATEAGDVSEESPIDAVSDENAQAEPDGGTESDDEE"
     gene            12381..13472
                     /locus_tag="EPL01_RS17695"
     CDS             12381..13472
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006882440.1"
                     /locus_tag="EPL01_RS17695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="trans-acting enoyl reductase family protein"
                     /protein_id="WP_135826616.1"
                     /transl_table=11
                     /translation="MTDELLIYGAYGYTGALVAETAVERGLSPVLAGRTAEKVERQATD
                     LGLDHRVFSLEHPEIVEDHVEEFSAVLNCAGPFSETARPMYSACLRTGTDYLDITGEID
                     VLEAIAERDRDAEEADVTLLPAVGFDVVPTDCLAAYLQTQLDSATRLTLAIDGLGTFSP
                     GTAKSIVEGLSRSGAVRENGELRTVPAAWKTRHLDFGRGPKPAVTIPWGDISTAYFTTG
                     IPNVETYATVPDYVPNVMEKTRPLVPLLGTEPVQSAMKAAIDAVVSGPTAEERAQSLAR
                     IWGEVEDDAGNRFAARMRTPDTYDLTAQTAVESARRVVEGEVNSGFQTPSSAFGPDYVL
                     EFDGVEREDVQEVSEVGASVLEE"
     tRNA            complement(13662..13736)
                     /anticodon=(pos:complement(30349..30351),aa:Thr,seq:cgt)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="EPL01_RS17700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /product="tRNA-Thr"
     gene            complement(13662..13736)
                     /locus_tag="EPL01_RS17700"
     gene            complement(13862..14890)
                     /locus_tag="EPL01_RS17705"
     CDS             complement(13862..14890)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008011644.1"
                     /locus_tag="EPL01_RS17705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class I SAM-dependent methyltransferase family
                     protein"
                     /protein_id="WP_135826617.1"
                     /transl_table=11
                     /translation="MEVPCVRVERERGEETRQRLADENLLAAEFEIEVAEGSLYLPVTD
                     ADRVPEDLTVVSRAVGERDTPDTPTDLLGYEPTYERLGDIAILDEDDPERAREIADAVM
                     ASDIPVKTVVNRASKVKGELRVRDWEVLAGDGTETVHREYGCEFLLDVSEVYFSPRLAT
                     ERHRVAEQVGEGPRPSKDASGDTPRATDERAFDMFAGVGPFVVPFAKRGAEVVGVDLNE
                     KAVEYLRENARRNDVEDRVTAIHGDVREVAPEYSDWADRVVMNLPHSADEFLDSAVELA
                     GDDCVIHYYDIQHEDDPFGPGEAAIREAAEPEYEVEVETRHVVRSYAPHELNVCLDVRL
                     SR"
     gene            15069..15842
                     /gene="dph5"
                     /locus_tag="EPL01_RS17710"
     CDS             15069..15842
                     /EC_number="2.1.1.98"
                     /GO_function="GO:0004164 - diphthine synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0017183 - protein histidyl modification to
                     diphthamide [Evidence IEA]"
                     /codon_start=1
                     /gene="dph5"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TP_methylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004057334.1"
                     /locus_tag="EPL01_RS17710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="diphthine synthase"
                     /protein_id="WP_135826618.1"
                     /sec_met_domain="TP_methylase (E-value: 2.4e-23, bitscore:
                     76.9, seeds: 87, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTFVGLGLYDERSITVEGKEVLREADRAFAEFYTSKLLGASVED
                     LEAYHDTDIEVRDRAGVEQDPEEILRAAESGDAVFLTAGDTMISTTHVDLRLRAEERGI
                     DTRVVHAPTAESAASGLTGLQNYRFGKATTLPFEYAHGADGVPASVTDAIDENRERGLH
                     TLVYLDIKVRNDEYMSADYAADLLAEEYGDLLGVVVARAGSPDPLVAADRISALADRDF
                     GDPLHLLVVPGDLHHIEADALGALAGAPEELLDVE"
     gene            complement(15867..16790)
                     /gene="artA"
                     /locus_tag="EPL01_RS17715"
     CDS             complement(15867..16790)
                     /EC_number="3.4.22.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0004197 - cysteine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006605 - protein targeting [Evidence IEA]"
                     /GO_process="GO:0043687 - post-translational protein
                     modification [Evidence IEA]"
                     /codon_start=1
                     /gene="artA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008389429.1"
                     /locus_tag="EPL01_RS17715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="archaeosortase A"
                     /protein_id="WP_135826619.1"
                     /transl_table=11
                     /translation="MTTALTDGLAWLVVGLFAAAAALDWYDDDHGRGRARYLAAFAWVV
                     FGVFWLALFPHFAFEQKSFVEGALSLAALPACLYAAYLLVQGRETLFLLSRAIAFMGLI
                     YLPFTMIPAGKEWLIETVAWQGEFVMETLGYEFEVVERDGGIRGTYFFHTNEGKFKVNV
                     LLACTGLGSMAIFGGLIAAVRAPLGRKLRGVAIAIPIIWALNLVRVVFITLAFSHQWLQ
                     FFVDPTMSLLGYQDPHMVSYFISDRVLAQVLSVVALVGIAWAVAREVPELLTVGEDVLY
                     IATGDEYDLHEAVGTDRPVATDGKGE"
     gene            complement(16976..18796)
                     /locus_tag="EPL01_RS17720"
     CDS             complement(16976..18796)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF045517.1"
                     /locus_tag="EPL01_RS17720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="BGTF surface domain-containing protein"
                     /protein_id="WP_246045738.1"
                     /transl_table=11
                     /translation="MSGEYVIVDNNGDAIEFENGASQGTPDSNPVSTSKWEVATQDFSA
                     SVNETNVTTADDVALSLDSNRGGYDVAVSSDDIDAEDLVDVFADGVATLNDDEDAVIID
                     GGADKTVEPLNFAEAGNYTLDLSVTDTDAEASVDVNVDEEGDAVYSLANSYPSDERGDV
                     GEFTVELENTQSAWVQFGTEEVNYAVYGKVTDEDGDGEVTVEVHTYETGTQDADAVLTD
                     TGGDDTVTEQGFRQNDDDEVLNTDSVIEAGDYDITVYDDNPTGDNAEEEAFGTFVLNER
                     STDAAQSWVAPAGASLDDSSDVYDAVSEGDTIAVDDYAIVQVQASGLYDYLDTGDHFDS
                     QNGLSVSFDHTNPGANQDGVAVDQESYDVVTDAQNNTFFIVLDTSDQDAFADGQEYEAT
                     FTIEGPESEDDDNYNKLVAEDESESVNTTFSLAESSVSFDTNRDDVYAVPNGEVNVTGT
                     SSLAPGSEFTVSARSTAANLLQSQTVTVDSDGAWTADFDFSEVENGTEFEFTNKETEDS
                     VDAVVDSSLEADSPSDNGTTTTTTTTTTTTTTTETTTTEEPTETTTTTTEEPTETTTTT
                     ASDGGIPGFGVSVALVALVAAALLALRRSN"
     gene            complement(<19046..19111)
                     /locus_tag="EPL01_RS22645"
                     /pseudo=""
     CDS             complement(<19046..19111)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR04207.1"
                     /locus_tag="EPL01_RS22645"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTTTNDKIRSVTLAAMLVLSVF"
ORIGIN
        1 taatcagcgt ctcgggctca ccatcggact tttaatttag aaaacaacta tatgaaataa
       61 tagtgtgacg atgagttctt agaaccccaa cgcctgcacc aacgtcatcc cactcgccaa
      121 agctccgacc agatacccgc cgattgcccc gccgttcagc agggggagtc cggcgtgcgc
      181 ccggcccttc atgaccatcc acagaagcac gaggaggccc gcaatcgtgc cgaccatcga
      241 ggtcagggcg ggcaggttga gcgcgaggcc cgaaatcagc ggctcggcgg gcgcgaaaaa
      301 ggccgcgctg gcgaccatca ccgtgggcat caccgcgtcg cccagtccga tgaagaacac
      361 gtctcgctct cccattcccg ggcgctcggc ctcggcgtcg gtctcggagg gttcgccgcc
      421 gtcagccgcg cttgcagttc cttcctccgg cgattcttcg tcctcggcgg ccatcccctc
      481 gtcgtcgagg aaggagtagg agagagacag cggaatcacg aggatgacgg gaatcttcag
      541 gtccatcacg cccgaggcca gcgtcagcat gtgttcggtg ccgtagacgc tgatggcgtc
      601 gtagatggca agcaccgaga gcaggaggat ggccgggagc aggccgaaac taatgccgaa
      661 cagtccggcc gcgccagccc ccatcaggac gcccgcggcg tcgatgacgt accactcggg
      721 gtggaccgcc agcgccagcg agaccaaccc ggccgcggcc agcgcgacga cgttgagggg
      781 agcgcccccg aacgagacga ccagccaccc cggaatcacg accgagaaga cgtaccacga
      841 cagcagtccg ctggtgaaga taatcgcccc gcggagcagc cactggacgt cgagtttgat
      901 gatgagcagc atcacgccgg tcaggaccag caccgccccg acgtagacca gactgttggt
      961 cgggtccgag gggttctcga cctgctggta gcccgcctgc tggaacggct cgaccagcgc
     1021 cagcgcgccg agttggacga gcagaaacat gaggaccgtc aacccgacgg ccgcgaacgc
     1081 acgcgttcgg ttctccatgt cgggtgcctc gcacccctcc gcctttgggg ttgtggtctc
     1141 ccctcgcgtg tcgggaaccg aaggcaaacg gcaggttttt gtcggtggcc cgcccgtgtg
     1201 acggtatgtc aacgcacggg acgcgagggg cgtcgccaga gtccgcccgc ctccccgacg
     1261 cggttccgtt cggcctgcct gcgctctctc ggctaagttg ggaactcggg tcgcgggtcg
     1321 tcgcggacgc gccgctcctc accgaatggg aacacgtcac gtccgggcgg acgctcgaag
     1381 tccacgacgt gaccgacaac accgtggtcc tcggcgtccg gacgccggtc ggccgcgagc
     1441 gcttcttcgg cgcggccaag gaggacttcg aggagaaacg cccgctactt tcggacgcgg
     1501 acgactggcg tcggcccgaa tagggaaacc tcggattcta ccgcgcgtac aacttctgcc
     1561 cgaggagcgt cgccagcgtg acgccctcgt ctggcgtgac cgcgacgtag ggccgggaga
     1621 cggggccgaa cacgtccacg actcggccga cgctgttgag ttgctcgtcc acggcctcgg
     1681 tgcccacgtc cgggtggtcg tcgtcggcac accgcacgac ggcgaggccc tgtgcggtcc
     1741 ggacgacttc gccgactcgt tgcatcaggc tctcacctca cttgcggagc gccgcgacgt
     1801 aggccgcgac agcctgaatc aagtcgttct tcgtcgagtc gtcggcgttc tggaccaaca
     1861 cgcggccgtt ctcctgccag ttctcgcggg agtaagcctt gtcgcgctcg attatcgcgt
     1921 cgtagccgac ctgctggacg gcctgtgcga tttcgtccac cgtcggctct tcgacggcca
     1981 tctcctcggc gacccggcgt ccctcgttgc gggtcttctc cgcgtcgaag tacgcgggcc
     2041 acagcacttt ctcgaccata cgtcaacgtc ttcttccggc ccctaaacaa cttaggaatc
     2101 gggtcggaga atagccggaa acgggctggc gaagcgatca gcgacgacgc gcgaggaggg
     2161 ccgcaccggc gagcgccgcg actgccgcgg tgacgccgaa gccgggggtg cttccggagg
     2221 acccgtcggc ggtcgcagta gtagtctcct cctgttcctg catcgcgccc tcgtcggtgg
     2281 tcgtctcggg cgattcagtc gtggtcggtt cgaccgtcgt ctcggtcgcc tcggtcgtgg
     2341 tcgcgttcgc ctcggcgtag gcgtcggggt ggaaggcctt cgccatcttc gtgatggcgt
     2401 agacgacgcg cggtgcgggc tggctgatgt tctcgttgct gaccgtgatg acgttgccct
     2461 gcttcaccgc gtcggtgccg ttgtaggcct cggtctcggg gtacgcgccg aacgcgccga
     2521 gttggacgat ccactcgggg ttctgctcga cgatgacctc ctcgctaatc ttcccgtagc
     2581 ccgagatgtt ggcctcggcg gcgacgttgg tcccgccagc gagttcgacc acgttgtcga
     2641 tgaacgtgcc ccctccggcg gtccaaccgg cgccctgcga gatgaagacc gtcgagcgct
     2701 cggagttctc gaccgcttct cggaccgtgc cgacgcggtc tttcatccac gagaccgtct
     2761 cggtcgcgcc ctcgcagttg cccgtgagct gacccatcag ttcggtcttc gcgtagatgt
     2821 cttcgacgga ggtggcgaag tcgaacttgt agacggtcag tccggcctct cggagcttct
     2881 ggaccgtctc gttcgggatg acgttgggcg cgaggaccaa gtccggctcg gtcgagacca
     2941 ctttctcgac gttgacgaac tgctggccgc tccccgagac gttggtcagc gagtcggtgc
     3001 cgtcgaggta ggcggcgtac tgagagacgc cgacgacctg cgacttaccg ccgatttccc
     3061 acatcgtctg ggccgcgctc ggcgacagcg tgacgactcg ctcgggcttc tgctcgaccg
     3121 tgacctcggt tcccgtcgcg tcggtgctgg tgacggggaa cgaacaactc gactgtgcgg
     3181 cgtctgccgt gccgccggtg actgctccga ccggcgcgac accggccgcg agcaacagca
     3241 ggaccgcaaa aacgctcgta accttctgtc tcatgcgtcc gcatctccgg ccgtatgcaa
     3301 taagtattta cctaaagcaa tcaggctttc acacgatggc tgattcggcg cgcgtcgtgg
     3361 gctggtcaat cggactcctc gccgcgctgg cggccgtggt ggtcgtcagc gccgcgattg
     3421 gcccggtgtc gctggagtat ctcgtggtcg ggaaagtgct attgaacgcg ctcgcggtcc
     3481 cggcgggcgt cggactcgcc gagcggacgc tccgaatcgc ggggctggcg gtcacggttc
     3541 cggggccgac cgtcgagttc gcgccggtgt tccacttcgc ggtgcccgag acggcccgga
     3601 ccatcgtcgt gaccctgcgc ctgccccgca tcgcgctcgg ggcggtcgtg ggcttcgccc
     3661 tctcgacggc gggggtcgtg atgcaggggt tcttccggaa tccgatggcc gacccctcca
     3721 tcatcggcgt ctcgtcgggc gcggcggtgg gcgcggtggc gaccatcgca atccccttcg
     3781 cagtcccgct cgcgctcccg accgcggcgt tcgtcggcgc ggtgctggcc gccttcggcg
     3841 tctacctgct cgccaccgag gagggccgga ctccggtcgc caccctcctg ctcgcggggg
     3901 tcgcggtcca gaccttcctc ggcgcggtgg tctcctttct gctcctccag agcggcgaga
     3961 gcctgcgccg ggcggtctac tggctgatgg gccacctgca tctggcctcg tgggaggacg
     4021 tgaccttcgt cctcccggtc gcaatcctcg gcttcgcggt gctgctggcc tacgcgcggg
     4081 acctgaacgt cctcttgctc ggcgaggagg acgcccacgc gctcggcgtc gaggtcgagc
     4141 gcaccaagcg actcctgctg gcggtcgcca gcgtgatgac cggcgcggcg gtggcggtct
     4201 cgggcgtcat cggcttcgtc ggcctcgtcg tgccccacgt catgcgcctg ctggtcgggc
     4261 cggaccaccg gattctcctg cccacctcgg cgctggcggg tgcgaccttc ctcgtcgcca
     4321 ccgacacggt ggcgcgctct ggtaccgcgg agctaccggt cggcatcgtg accgccttcc
     4381 tcggcgcgcc gtttttcctc tatctcctcc ggactcggga ggtgcatgcg ctgtgaaccg
     4441 atttttcgga cgacgacgtt tcgacctcct cccggcgcgc gctggagcgg cgtctcgtcg
     4501 ccgcgccatc gtcgcgcgag ggatgaggac cacagggagg agcgaagcga cgaccgagga
     4561 ccgcaatcgg ttggggagga cgtggcccac gcgctcggcc gatggtccac cactcgcgct
     4621 cggccaaacc aaccaccgag gacgcgctcg accgaccgaa ccacagcggg tggatgaagg
     4681 ggccgcccgc tcgcggggcg gaggcccgtg gtcgtctggc cgacccctat ccggaccggg
     4741 cggtgcggag aggtccggat atgtcggcca gcgaccgcga gcgggcgggg gcttcagagg
     4801 aagaaacctc gaaagttctc atcccaactc caaaccgaac ccatcgaagc gagcgggcgg
     4861 ggatttcaga ggcgttcacg tcctcagttc tggcctcgaa acgggctcta ccgactccgc
     4921 tctcagcatc tcttcgactg attccttcaa cacaaaatcc gccagaggag gtcccaagaa
     4981 ccgatgatac gaatccaaga cctagaagtc gaactcggcg ggaccgaaat cctcgacggc
     5041 gtaaccacgg aaatcgaaga cggccagttc gtcggtctcg tcggtcccaa cggcgcaggc
     5101 aaaactacat tgcttagagc aatcaatggt gttctaaaac ctgattctgg aagtgtctac
     5161 gtcgatagcg accccgtcgc cgacctctcc tcgaaggagg ccagtcgtcg catcgcggtc
     5221 gtcccgcagg acaccagcct ctcgttcgac ttcccggtcg aggaggtcgt ggcgatgggt
     5281 cgccacccct atcggtcgcg gttctccggg ccgaaaccct ctaccgacgg cgactcagac
     5341 cagcaaatcg tcgaggaggc gatggcgcgc accgaggtcc aacacctcgc cgagcgttcc
     5401 attaccgccg tctcgggtgg cgagcgccag cgcgtcctgc tggctcgcgc gctggcccaa
     5461 gacacccccg cgctcctgct ggacgaaccc accgccagcc tcgacatcaa ccatcaggtc
     5521 cggacgctcg aactcgtccg cgaactcgcc gacgagggca agaccgtcgt ggcggccatc
     5581 cacgacctga atctggcggc ccactactgc gacgaactcc gcctgctggc gggcggcgag
     5641 attcgcgcca gcggcgaccc cgcggacgtg ctggccgagg accacctcga agcggccttc
     5701 gacacgcgcg ccgtggtctc cagccacccc gtcacgggtt cgacgtacgt cacggccctg
     5761 ccagagcgcc ccgacgacgc ggcgggccga gtccacgtcg tcggcggcgg tggaaccgtc
     5821 tcccgactgc tctatctcct ctcggcggcg ggctacgacg tgtcggtcgg cgtcctcaac
     5881 gagggcgact cggacctcga aaccgctcgg tcgctcggcc tcgacgccgt gacagaagag
     5941 ccgttcgcgc cggtcggcga ggcggcccgc cgcgaggccg aggagagaat ccgcgaggcc
     6001 gacgccacga ttctcgcgga cgtggaagtc ggcgcgggca acgtcgccaa cctccgggcc
     6061 gcccgggagg ccgactcggt ggtcgtggtc gaggagcgcc ccttcgccga gcgcaacttc
     6121 gccgggagcg acgccgcggc gctctaccgg gaactctgcg agcgcgggca ggtcgtcggg
     6181 ccggacgaac tcctctcggc ggtcgagcgc gcggtcggag aaaagcgggc gtcggcgcgg
     6241 tgcgacgcta cctgaccggc gcttacgacg cgactcgctg gcgctgctgg agcaactcga
     6301 acagcatcag cgccgcgaac gtgctggccg ccagtagcac catcccggcg atacccacgt
     6361 ccaccgaggg cgcggccatg ctcgccgtcc cgaggacgcc gcccgagagg agcgcaatcg
     6421 ccatccgcgc gggccgcgag aagctcgcac atcgctgggc gagcgtgggg tccagaccca
     6481 cgattcgagt ccagacgacg tacagcgaca ccacgaacag aaacgagagc agaccgacgc
     6541 ccagcaggag ggcgaacttc gccggattca tttcctgttt tcaacagcat cagggttcgg
     6601 atataagcct atcggagata cgtctcaatc gttacacgac ggcgagtgaa tccggtcctc
     6661 ctcgggggtg aaaccggtcc gccaatttat gtgactcgcg ccctcagaat ccgacatgca
     6721 actctcggac cggtcggtcg cggtcgtcgg aagcggtttc ggcgggctct cgaccgcctg
     6781 ttacctcgcc gacgcgggcg ccgacgtgac tgtcgtggag aaaaacgagc agctgggcgg
     6841 ccgggccagc gtcctcgaac gcgacgggtt ccggttcgac atggggccgt cgtggtatct
     6901 gatgcccgac gtgttcgagc gcttcttcgg ccacttcggc cggagtccga gcgagtacta
     6961 cgaactcgaa cacctccacc cccactacaa gattttcttc aaggacggcg accgcgtcac
     7021 cgtcacggcc gaccgcgagg agaccaaggc caccttcgag gagtacgagc gcggggccgg
     7081 gccggccctc gacgcctacc tcgaggaggc cgaagagacc taccaaatcg ggatggaaca
     7141 cttcgtctac accgaccggc cccggttccg cgactacgtg gactgggacg tggtccgcca
     7201 cgcccgcggc ctgaccttcc tcgggtcgat gcaggaccac gtcgccgact acttcgacca
     7261 ccccaaactc cgccaaatca tgcagtacac gctggtgttc ctcggcgggt ccccgaagaa
     7321 caccccggcg ctctacaacc tgatgagcca cgtcgatttc aacctcggcg tccactaccc
     7381 gagagccaag gacgggaccg cgaccgacgg cggggacgcc gacggaacca ctcccggcgg
     7441 gatgggcgtc gtcgtggacg ccatcgccga gatgggcgaa gaactgggcg tcgagtaccg
     7501 gaccggcagc gaggtcgagt cgattctggg gtcggcgggg aacttccgag tggagacgga
     7561 agacgggttt ctcagagccg acctcgtggt cagcgacgca gactacgccc acaccgaaca
     7621 ggaactcctc ccgccacaga gtcgccagta cgacgccgac tactgggagt ctcggaccta
     7681 cgcgccctcg gccttcctgc tgtacctcgg cgtcgagggc gacgtggacg gcctcgaaca
     7741 ccacaccctc gtcctgccga ccgagtggaa cgaccacttc gacgagattt tcgaggagcc
     7801 agcgtggccc gaggacccgg cgtactacct ctgcgtgccc agcgagaccg acgacacggt
     7861 cgcgcccgag ggccacagca acctgttcgc gctggtcccc atcgcgcccg gcctcgacga
     7921 cggccccgag accagacggc gctaccgcga cttcgtgctg gacgacatcg ccgagaacac
     7981 cggggtagac ctccgagacc gaattgtcct cgaggagtcc ttctgcgtct cggacttcgc
     8041 ggagcgatac aactcgattc agggcaccgc gctcggcctc gctcacaccc tgcgccagac
     8101 cggcccgctc cggcccggcc atcgctcctc ggaggtcccg ggactgtact tcacggggtc
     8161 gttcaccacg cccggaatcg gcgtcccgat gtgtctcatc agcggccagc acaccgccga
     8221 cgccctgctg gaggactacg gcgagtagcg ccatgctgag gtacctcctc aaactctctc
     8281 ggccccggtt ctggctctat ctggccggac cggtcctcgt gggggtcgcc tacggcgcgt
     8341 ccgccccgag cgacctgttc gccccggccg gggtcgcgct gttcgcgtac ttcctcctgc
     8401 ccgcgaacgt ctacctctac ggcatcaacg acgtgttcga cgcggatatc gacgaggaga
     8461 acccgaagaa gacgggcgag gaggcacccg aggcccggtt ccggggcggg accgccgtca
     8521 ccctcctcgt cgcgctctgc ggcctcgccg gtttcgcgct ggcgggtgcc ttcgccgtcg
     8581 gggcgctcgc actcgggtcg aatccgccga tgggtgcgac cgtgggcgtg gctgtctggg
     8641 tcgtcgcctt cctgctcttg gggtacgcct acagcgcgcc cccgttccga ctgaagaccg
     8701 tgccgcctct cgattcggtc tcgaacggtc tctacgtcct gccgggcgcg gcggcctacg
     8761 tcgcgctggc gggtcgccaa cctcccgcgc tcgcggtcgt ctcggggtgg ctctgggcga
     8821 tggcgatgca caccttctcg gcgattcccg acatcgaacc cgaccgccgg gccgggattc
     8881 ggaccaccgc gaccgtgctg ggcgagcgcc ggaccttggc ctactgcggg gtctgctggt
     8941 tgctcgcggc gggagccttc ggcctgctgg atattcgggc cggggcgctc ctcttgctct
     9001 atcctctctt cgcactcggg gtcgccgaga ccgacgtttc ggtctcgcgg gcctactggt
     9061 ggttcccggc catcaacacg ctggtcggga tggtgctgac gctcggcggt ctctgggggg
     9121 tcgtgcgtgg gtaacctgag tagaacccag gtcgagcgcc gactctcgga cctcgtccgc
     9181 gagaaccggt ttaccatcgc ggtcgtcttt ccgctggtcg gggccgggat gttcgtcgcc
     9241 agtcacgagg ggtggctccc gccgtggctg gcgatgaatc ctctgctggt cctgttcggc
     9301 acgctcgtga tgcgcctgcc gctcgtggcg ggtctcgcgc cgctggtgga ccgccgggcc
     9361 ggagtcggcc tgcttctggt cacggcctac agctacgtca tcgagtacat cggagtccac
     9421 tacggcgtcc cctacggcga gttcagctac caaatcgagt tgggaccgat ggtcggcgga
     9481 gttccggtcg gcctgcccgt cttcttcctc ccgttggtgg tcaacagcta cctcctcgtc
     9541 ctacttctgc tcccgaaggc aggccggata gctcggaccc tcgcggcgct cgcggtcgtg
     9601 ctggtcgtgg acttcgtgct ggaccccgcg gcggtcggac tcggcttctg ggactacggc
     9661 ggcgggttct actacggcgt ccccttctcg aactttcagg gctggattct gagcggcctg
     9721 attgcggtct cgctcgttga gtggggattc gaccgcgcgg cgctcggcga ccgactccgg
     9781 aactgcgagt tcgcgctcga cgacttcgtg agcttcgtcc tcctctgggg cgcgatgaac
     9841 gtctacttcg ggaactggat tgcggtggcg ctggccgcgg gactctcggc cgggttggtt
     9901 cgaaccgacc gcttcgactt cgtcggaatc ggccgggaac gccccgaaca gggttgaaaa
     9961 actccaaaat cgccgggaag agaccaccga ggagccgggt tcaatcggcc tgcggtgccc
    10021 cttccgggcg atggctggcg tggactttct cggcctcggg gacggcgctc acggcccgga
    10081 acaccgtcac cgggtcgcgg gacttctgcc agtaccaccg ggtcttcgcc cagagccacg
    10141 cggcgcggaa ggctccgacc tccggctccg aggagaacac gtcgtaatct cgcgctcgga
    10201 tgaggcggtg gtgttcggcg tagaggaccg cggcgtacag caccgcgaac tggcagtcct
    10261 cgggcaggta ctcgatgccc gccacgccct cgcggtactt gcgctcggcc cgccggagtt
    10321 cgtcggccat cgccgcgcgg aagccgtctg tcgggttgca acgccgaatg tcggcctccg
    10381 tgacgccgtg gcgctcgcgg gtggttccgg ggaggtagat gcggtcgtgg tccagaatgt
    10441 cctcgcgcac gtcgcggagg aagttcgtca actggaaggc ctcgccgagt gcgaccgcgt
    10501 gaggtttggc gcgctcgggt ttctcgacgc ccatcaccga ctgcatcatc acgccgaccg
    10561 cggaggccga cccgcgcatg tactcctcga gttcggcgta ggtctcccag cgggacttct
    10621 cgatgtccga aatcatcgcg tcgatgaaga tttctatctc ctcgtcggga atcccgcgct
    10681 cgtcgctgac ctcctgaaac gccgcgagca cctcgtcgtc cgtctccact tcgccgagcg
    10741 cctccgcccg gagttgttcg agtcgcgccc gttgctcgtc gggcggtaag tcgtcggcac
    10801 cgtctacgac ctcgtcggcg acgcggaaga acgcgtagag gacgtacgtg ggattgcgta
    10861 tccgccgggg gagcaaccgc gtagcgaagt ggaaggttct gccggttcgc tgctgaatcg
    10921 tcttacttcg tcggagttgt cggtcggtga ccattcgatc tctcctgtgt tgtgcagagt
    10981 ccggtcgaac agcagcggcc ccagcatttc acctagggag tcgtccgtgt taattgttgg
    11041 cgtcggtgaa ctcccggcgg gcagacagtc cgcgcggtag gatgtcctta ctgagcgtaa
    11101 tctgggttac gaggtccgga gttcgccgcg agcgcttccg gactgccatc acgcctttct
    11161 acgtcggtgc cctcgattcg gacgtatgag ttcttccgac gccgtcaccg agacgttaga
    11221 cgagggtgga aacggaatcg cgggtcgagt cgggtcgctg gcgaagccgc tcggaccggc
    11281 gctcgccaag cacgccgagt cgggcaccct cgcggccgcg tcgggggtcg tctcgctggt
    11341 ccgggccggg cggaccttct tgaagggcaa ccgcaagcgc ggcgtcttgc aggcgctcgg
    11401 aggcctgttc tgggtcggcg tcgcgctcgc ccagcgccgg acgggacgcg gttcgaccgc
    11461 cggagcgacc cgaggaggac cctctacctc cgacctcgcc gacgtggccg actcctcgcc
    11521 ggacatcgag gatgtcgaaa ccgaaggcac ggacgccgac cacgccacgg gcgaggaggt
    11581 cgtggatacg accgacgccg acatcgagga gtccgacacc gcgccggaag tcgagtcgca
    11641 cgccgagggc gacgtggacc agcgcgacgt ggtggagtcg ggtgacctcg aagacgcgga
    11701 cgccgatgaa gagagcgaag cagggtccga ggacgcgacg gaggcaggag acgtctccga
    11761 ggagtcgccc atcgacgcgg tcagcgacga gaacgcgcag gccgaacccg acggcggcac
    11821 cgagagcgac gacgaggagt gactcaggac tcggcggagc ccgatcaaag ccttgtattt
    11881 gtttctctgg gcaattataa tatttcctaa ccaattatat atgatccttt gtccagaaat
    11941 ccgcgagtgc ggcccggcgg ccagcggccg ccgggccgcc gaacgcccgg ccgaccaaac
    12001 agccagcaaa cgctcgtcca gccatccacc ggcgaacgcc cggccaacca accgccggga
    12061 acgcgctcgg tgaaacaatc accacgggag gatgaagggg ccggtcgctc gcgttcactt
    12121 tagtcgtctc cgcgggcact actcgcgccg ggcggtgtct gcgggagcga agcgaccaaa
    12181 ggctcgtcgg agctcgtctc cgacggtgcg gagaggcgcg agtatcccgc ggagcgaccg
    12241 cgagcgaccg ggggcttcag aagacatcat cacagtagtt ctgctgttcg cactctcgtt
    12301 cgcaatcgtc gtcatagcaa gaactccctc acctagaatc ggccccgcga gttttacccg
    12361 tcaccgtcta atccgacatc gtgaccgacg aactgctcat ctacggagcc tacggctaca
    12421 ccggcgcgct cgtcgcggag acggcagtcg agcgaggtct ctcgcccgtc ctcgcggggc
    12481 gcaccgccga gaaggtagag cggcaggcga ccgacctcgg cctcgaccac cgggtgttca
    12541 gcctcgaaca ccctgaaata gtcgaggacc acgtcgagga gttctcggcg gtgctgaact
    12601 gcgcggggcc gttctccgag acggcccggc cgatgtactc ggcgtgcctg cgcaccggca
    12661 ccgactatct ggacatcacc ggggaaatcg acgtgctgga ggccatcgcc gagcgcgacc
    12721 gggacgccga ggaggccgac gtgaccctcc tcccggcggt gggcttcgac gtggtgccga
    12781 ccgactgtct ggcggcctac ctccagaccc agctggactc ggcgacgagg ctcacgctcg
    12841 ccatcgacgg actgggcacc ttctcgccgg gcaccgccaa gtccatcgtg gagggcctct
    12901 cgcgctccgg cgcggtccga gagaacggcg agcttcggac cgtccccgcg gcgtggaaga
    12961 cccgccacct cgacttcggg cgcggcccca agcccgccgt gacgattccc tggggcgaca
    13021 tctcgacggc ctacttcacc accgggattc cgaacgtcga gacctacgcc accgtgcccg
    13081 actacgtccc gaacgtgatg gagaagaccc gcccgttggt gccgctcctc gggaccgaac
    13141 cggtccagtc cgcgatgaag gccgccatcg acgccgtggt ctcgggaccg accgccgagg
    13201 agcgcgccca gagtctggcc cgcatctggg gcgaagtcga ggacgacgcg ggcaaccgct
    13261 tcgccgcccg gatgcggacg cccgacacct acgacctcac cgcccagact gcggtcgagt
    13321 ccgcgcgccg ggtggtcgag ggcgaggtca attctggctt ccagacgccc tcctcggcgt
    13381 tcgggccgga ctacgtgctg gagttcgacg gggtggagcg cgaggacgtg caggaggttt
    13441 cggaggtagg tgcgagtgtg cttgaggagt aacagctttc accgatagcc gattcgctgt
    13501 cgaggaatac tcgacactca ccgtataatt cgtggaaaag taagccggtg gagggattat
    13561 gaaccacctg aaaacgcttc ctcgccttcg gcgagactgc cttttccgta gttcaaatcc
    13621 tctacagaag gctcttcagc ctcactacgt tcggcagaaa gagccggtgg agggatttga
    13681 accctcggcc tattccttac gaaggaatcg ctctagccag tctgagctac accggcacac
    13741 tcacttcgtt cgtgtcccga gcctcgcctc gcgttgctcg gcgagacacc ggcgcgcgta
    13801 cttcctcttc actctttact actccccaca ggcaaaataa ggcttccgga atcgcccgcc
    13861 gttagcgaga tagtcgcacg tcgagacaga cgttcaactc gtgaggagcg tacgaccgga
    13921 ccacgtggcg cgtctcgact tcgacttcgt actcgggttc cgcggcctct cgaatcgcgg
    13981 cctcgcccgg cccgaagggg tcgtcctcgt gctggatgtc gtagtaatga atcacgcagt
    14041 cgtcgccagc gagttcgacc gccgagtcga ggaactcgtc ggcgctgtgg ggcaggttca
    14101 tcaccacgcg gtcggcccag tccgaatact cgggcgcgac ctctctcacg tcgccgtgaa
    14161 tcgcagttac cctgtcttcc acgtcgttgc gccgggcgtt ctcccggagg tactcgacgg
    14221 ccttctcgtt caggtccacg ccgacgacct ccgcgccgcg cttggcgaag gggacgacga
    14281 acggcccgac gcccgcgaac atgtcgaagg cgcgctcgtc ggtcgctcgc ggggtatccc
    14341 cgctcgcatc tttcgagggc cgtggcccct cgccaacctg ctcggcgacc cggtggcgct
    14401 cggtggcgag ccgaggagag aagtagacct cggacacgtc gaggaggaac tcgcagccgt
    14461 actcgcggtg gaccgtctcg gttccgtctc ccgcaagcac ctcccagtcg cggacccgga
    14521 gttcgccctt gaccttcgag gcccgattca cgaccgtctt cacggggatg tccgaggcca
    14581 tcacggcgtc ggcgatttcc cgggcgcgct ccgggtcgtc ctcgtctaag atggcgatgt
    14641 cgccgaggcg ctcgtaagtc ggttcgtagc ccagcaggtc ggtgggcgtg tccggcgtgt
    14701 cgcgctcgcc gacggcgcgc gagactacgg tcaaatcctc gggcactcgg tcggcgtcgg
    14761 tcaccgggag gtagaggctc ccctccgcga cttcgatttc gaactcggcc gcgaggaggt
    14821 tctcgtcggc caaccgctgg cgagtctcct cgcctcgctc gcgctcgact cgcacgcacg
    14881 ggacttccat actctcgctt ttcggggtgt ggcggtaagc gtgacgcttc gcggtcgtcg
    14941 tgggtgtccg tgggtggtcg tcggtcgtcg tggttcgccg gtgggtccag ccccgacgca
    15001 ctcgtcgtcg ggccagcgag cgcgtccgac tcgaaacgct ataacccgct ggcgtcccta
    15061 ccggaggtat gctcacattc gtcggcctcg gtctctacga cgagcgttcg attaccgtcg
    15121 agggcaaaga agtcctccga gaggcggacc gcgccttcgc cgagttctac accagcaaac
    15181 tcctcggcgc gagcgtcgag gacttggaag cctaccacga caccgacatc gaggtccgcg
    15241 accgggcggg cgtcgagcag gaccccgagg aaattctccg ggccgccgaa tctggcgacg
    15301 cggtctttct caccgcgggc gatacgatga tttcgaccac tcacgtcgac ctccggctcc
    15361 gggccgagga gcgcggcatc gacacgcgcg tcgtccacgc gcccaccgcc gagtcggcgg
    15421 ccagcggcct gaccggcctc cagaactacc gcttcggcaa ggccacgacg ctccccttcg
    15481 agtacgccca cggtgccgac ggcgtccccg ccagcgtcac cgacgccatc gacgagaacc
    15541 gcgagcgcgg cctgcacacg ctggtctacc tcgacatcaa ggtgcgcaac gacgagtaca
    15601 tgtccgccga ctacgccgcc gacctgctgg ccgaggagta cggcgacctg ctgggcgtcg
    15661 tggtcgcccg cgccgggagt cccgacccgc tcgtggccgc cgaccgcatc tcggcgctgg
    15721 ccgaccgcga tttcggcgac ccgctccacc tgctggtcgt gccgggcgac ctccaccaca
    15781 tcgaggccga cgcgctcggc gcgctggcgg gtgcgccgga ggaactcctc gacgtcgaat
    15841 aattctaaac actgagccgc gctcgattac tcgccttttc cgtcggtcgc aacgggtcgg
    15901 tcggtgccga ccgcctcgtg gaggtcgtac tcgtcgccgg ttgcgatgta gaggacgtcc
    15961 tcgccgaccg tcagcagttc ggggacctcg cgggccaccg cccacgcgat accgaccagc
    16021 gcgaccaccg agaggacctg agccagcacg cggtcggaga tgaagtacga caccatgtgg
    16081 gggtcctgat agcccagcag gctcatcgtc gggtccacga agaactgcaa ccactggtgg
    16141 ctgaacgcca gcgtgatgaa gaccacgcgg acgaggttca gcgcccagat aatcgggatg
    16201 gcgatggcga cgccccggag cttgcggccg agcggcgcgc ggaccgcggc gatgaggccg
    16261 ccgaagatgg ccatgctccc gaggccggta cacgccagca ggacgttgac cttgaacttg
    16321 ccctcattcg tgtggaagaa gtacgtcccg cgaattccac cgtcgcgctc gaccacctcg
    16381 aactcgtagc ccagcgtctc catgacgaac tcgccctgcc acgccaccgt ctcgatgagc
    16441 cactccttgc cagcgggaat catcgtgaac ggcaggtaga tgaggcccat gaacgcgatg
    16501 gcccgcgaga gcagaaagag ggtctcgcgg ccctgcacca gcaggtacgc ggcgtacagg
    16561 caggccggaa gcgcggccag actcaacgca ccctccacga agctcttctg ctcgaacgcg
    16621 aagtggggga acagcgcgag ccagaacacg ccgaagacga cccacgcgaa cgcggcgagg
    16681 tagcgagcgc gcccccggcc gtggtcgtcg tcgtaccagt cgagggcggc ggccgcggcg
    16741 aacagtccga cgacgagcca cgcgagtccg tctgtcaacg cggtagtcac ggttagaagg
    16801 acgaaagcgc gccccggata aagagttgac ggctcgtctc aaatcgagta acgtctgcct
    16861 agtcgggtcg aaacgcggcg tttcccacgt gcgacgacgc tgtcgctacg ggagttggca
    16921 cgccgaaaaa atgaaaccgc gaaagaccgg cgaaagccgg tggttagtta gctatctagt
    16981 tgctgcggcg gagagccagc agcgcggcag cgacgagggc gacgagcgcg acactcacgc
    17041 cgaagccggg gatgccaccg tcactcgcgg tcgtggtggt ggtctccgtg ggctcctcgg
    17101 tcgtggtggt cgtcgtctcg gtcggctcct cggtcgtcgt ggtttccgtc gtagtcgtgg
    17161 tggtcgtcgt agtcgtcgtg gtcgtcgtcg tcccgttgtc cgacgggctg tcggcctcga
    17221 ggctggagtc cacgacggcg tcgacgctgt cctcggtctc cttgttggtg aactcgaact
    17281 cggtgccgtt ctcgacctcg ctgaagtcga agtcagcggt ccacgcaccg tcagagtcga
    17341 ccgtcacggt ctggctctga agcaggttcg cggcggtcga acgggccgac accgtgaact
    17401 cgctaccggg cgcgagcgag gacgtgccgg tcacgttgac ctcgccgttc gggacagcgt
    17461 acacgtcgtc acggttggtg tcgaagctaa ccgagctctc ggcgagcgag aacgtcgtgt
    17521 tgacggactc gctctcgtcc tcggcgacga gcttgttgta gttgtcgtcg tcctcgctct
    17581 cgggcccttc gatggtgaag gtggcctcgt actcctggcc gtccgcgaag gcgtcctggt
    17641 cggacgtgtc aaggacgatg aagaacgtgt tgttctgggc gtccgtcacc acgtcgtagc
    17701 tttcctggtc gaccgcgaca ccgtcctggt tggcaccagg gttggtgtgg tcgaagctca
    17761 ccgacagacc gttctggctg tcgaagtggt cgccggtgtc gaggtaatcg tacagaccgg
    17821 aggcctgaac ttggacgatt gcgtagtcgt cgacggcgat ggtgtcgccc tcggagacgg
    17881 cgtcgtagac gtcactggag tcgtcgaggg aggctccggc aggggcgacc cagctctggg
    17941 ccgcgtcggt cgagcgctcg ttcagcacga acgtcccgaa cgcctcttcc tcggcattgt
    18001 cgccagtcgg attgtcgtcg tagacggtga tgtcgtagtc accggcctcg atgacgctgt
    18061 cggtgttcag gacttcatcg tcgtcgttct ggcggaagcc ctgttctgtg actgtgtcgt
    18121 caccgccagt gtccgtgagg acggcgtcag cgtcttgggt accggtctcg taggtgtgga
    18181 cttcgacggt gacttcgccg tcgccgtcct cgtcggtcac cttaccgtaa acggcgtagt
    18241 tgacttcttc ggtgccgaac tggacccaag cactctgggt gttttcgagt tcgacggtga
    18301 actcgccgac gtcaccgcgc tcgtcgctcg ggtaggagtt cgcgagcgag tagaccgcgt
    18361 cgccctcctc gtcgacgttg acgtcgacgg aggcctcagc gtcggtgtcg gtcacgctca
    18421 ggtcgagcgt gtagttaccg gcttcggcga agttgagcgg ttcgacggtc ttgtcagcgc
    18481 cgccgtcgat gatgaccgcg tcctcgtcgt cgttgagcgt ggcgaccccg tcggcgaaga
    18541 catcgacgag atcttcggcg tcgatgtcgt cggacgagac cgcaacgtcg tagccgcccc
    18601 ggttggagtc gaggctgagc gcgacgtcgt cagcggtcgt gacgttcgtc tcgttcaccg
    18661 acgcactgaa gtcctgcgta gcgacttccc acttggaagt ggagacaggg ttactgtcgg
    18721 gggtgccctg agaagcacca ttctcgaact cgatggcgtc accgttgttg tcaacgatga
    18781 cgtattcacc gctcaagtcg ctggtcgaga tgactgcctg accagatccg ttgagggtga
    18841 attccgtcgt aagaccgcca atctctccgt catcatttac ttctcgaatc tgccaagttt
    18901 cgtcgtcagc atcgttccca gcgttaaccc acacggattg gccggcccag tatgtcgcac
    18961 cggagtcggc agcagtatcc gcgccagctg cgtctgcact gttcgcgacg gcggccgccg
    19021 agcctgcgaa ggcggcggta ccggcgaaca ccgacaggac gagcatggca gcgagggtta
    19081 cgctgcgaat tttgtcgttt gtcgttgtca tggtttggat tggttattca gtcggcgaca
    19141 gcacctttcc cgtggccctc gggggaaccc ggaaccgcac cggatgtggg ccacctgtac
    19201 tcgctactgc caccatgggt aggggtacag acgaaaggtt acgccgtggt tataagtgct
    19261 ttgtggtctg agaatcctct cgttactggt tgtcacgacg agttattgcc gcgttacgaa
    19321 gcagtagaga ggccgatggt ggcgtatacc gtagaacctg ttttctcacg agtacggtga
    19381 tacgtctcgg agccgattct atcgtatacg ccagtttcga ccggtatcgg tcggtttctc
    19441 ggagagagga cctcgccgaa acctcggtaa gcctactggt actgccgctt aaaaagaaaa
    19501 ccaggtattt cgaagcgcga ctgccgggcc gaacgagtgc ggcgtcgaag ccgagttact
    19561 ggctccgact gcgacgaatc gccagcagcg cggcggcgac gagtgcgacg agtgcgacac
    19621 cgagaccgaa gccggggatg cctccgtcgg tcgcttcggt cgtggtagta gtctcctcag
    19681 ttgtcgtcgt ctccgtcgtg gtggtggtgg tctcttcggt ggtcgtagtc gtcatggtgg
    19741 tcgtcgtcgt ggtggtcgtc gtcgtagtgg tcgtcgtcgt cgtttcgcca gcgccttgga
    19801 agtcagcgtc gacgagcgca ctcacgctgt cgtctgttcg accgttagtg aacgtgaact
    19861 cggtgccgtt ctcgacttcg ctgaagtcga agctggcgtt ccacgtaccg tcagcatcga
    19921 ccgtcacctg ctggctctgg aggaggttcg cggcggtcga gcgggcagtg acttggaagg
    19981 tcgtgccggg cgcgaacgtc gacgtgccgc tcacgttgac ctcgccgttc gggacgacgt
    20041 acacgtcctc gcgggtagtg tcgaacgtga cctcgctctc gaccacggag aacgtcgtgt
    20101 tcaccgactg tgactctcct tcgggaagga gcttgtttcc gtcaccggtt tcgttgctga
    20161 cggtgaaggt cgctcggtac tgctgaccgg gttgtgccgc ggacgtgtcg atggccacga
    20221 agaacgtgtt gttctccggg tccggaatga ccgcgtagtt ttcggccgaa atctcgttcg
    20281 gctcctgatt cgcaccgggg ttcatctgta cgacttccat cgacagcccc tccgtgccga
    20341 gttcgaagta gtcgtagaga ccggaggcct gaacctgcac gactgcggcg tcaccttctg
    20401 cgacagtatc gctttcggcg acggcgtcgt agacctcacc ggcgtcggcg aggttagcgg
    20461 ttggcgcgac ccacgtccga gcgctatcgg tcgagcgctc gttcagcacg aaggtcccga
    20521 actcagcctc ttcgccagcg ctatcgtaga tcgtgaggtc gtagtcgccg gcctcgattg
    20581 gcgtgttcag attcgatccg gcggtgaacg actcgttgct gatttcgtcg ttcgagcctt
    20641 ctgcgagcgt aatgacgctc gatgcggtac ctgtgtcggt ctcatacgtg tgaagcgcaa
    20701 gcgtgacctc accgtcatcg tcggcgtcgg tcacgtcggc ccacaccgcg tagttgacgt
    20761 cggcgctacc gaacttgacg gtagcggtat cggtgttgtc gagttcgacg gtgaaggtgc
    20821 cgacgtcacc gcgctcctcg ctcgggaagg ggttcgcgag cgagtaggag gccgcgccct
    20881 gttggtcgac gttgacgctg accgacccag aggcgtcggt gtcgacgact tccatgtcga
    20941 gcgtgtagct tccc
//
