LOCUS       NZ_SBIT01000010        23183 bp    DNA     linear   CON 23-OCT-2024
DEFINITION  Halorussus ruber strain YC25 Scaffold8_1, whole genome shotgun
            sequence.
ACCESSION   NZ_SBIT01000010
VERSION     NZ_SBIT01000010.1
KEYWORDS    WGS; RefSeq.
SOURCE      Halorussus ruber
  ORGANISM  Halorussus ruber
            Archaea; Methanobacteriati; Methanobacteriota; Stenosarchaea group;
            Halobacteria; Halobacteriales; Haladaptataceae; Halorussus.
REFERENCE   1  (bases 1 to 252989)
  AUTHORS   Cui,H.-L.
  TITLE     Genome sequence of Halorussus ruber YC25, isolated from an inland
            salt lake of China
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 252989)
  AUTHORS   Cui,H.-L.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-JAN-2019) School of Food & Biological Engineering,
            Jiangsu University, 301 Xuefu Road, Jingkou District, Zhenjiang,
            Jiangsu 212013, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. Dec-2018
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004765785.1-RS_2024_10_23
            Annotation Date                   :: 10/23/2024 04:20:59
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,396
            CDSs (total)                      :: 4,336
            Genes (coding)                    :: 4,270
            CDSs (with protein)               :: 4,270
            Genes (RNA)                       :: 60
            rRNAs                             :: 3, 3, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1 (5S, 23S)
            partial rRNAs                     :: 3 (16S)
            tRNAs                             :: 51
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 66
            CDSs (without protein)            :: 66
            Pseudo Genes (ambiguous residues) :: 0 of 66
            Pseudo Genes (frameshifted)       :: 18 of 66
            Pseudo Genes (incomplete)         :: 50 of 66
            Pseudo Genes (internal stop)      :: 6 of 66
            Pseudo Genes (multiple problems)  :: 7 of 66
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:04:38
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 155500
            Orig. end                         :: 178683
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            SBIT01000010.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23183
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="2"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..23183
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23183
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13183](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13183
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            complement(404..1135)
                     /locus_tag="EPL01_RS17060"
     CDS             complement(404..1135)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006672588.1"
                     /locus_tag="EPL01_RS17060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF2103 domain-containing protein"
                     /protein_id="WP_135826484.1"
                     /transl_table=11
                     /translation="MDCRQCASPLERPGDYCLVCRTPNADAVVLELDRDHATLTMLDDE
                     EVVGKTDVSTTPEEGGEAGVVELRNFAGRVADEVRRKRPEEIYAAGDREVLRAARDQLH
                     HSFYRVGDGDEAEDPVEAVLARRGDRALEVVEASPAEKLGGSHSTLIGDRAGRTAIQTV
                     AGHPHVKKIIPGPIDAGGSGSRTGVRAKATRADENGNVRLLLRDGSSVQENRVVTTAMD
                     RERGERVRADLNDALAEAELQ"
     gene            complement(1189..1563)
                     /locus_tag="EPL01_RS17065"
     CDS             complement(1189..1563)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007108160.1"
                     /locus_tag="EPL01_RS17065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="WP_135826485.1"
                     /transl_table=11
                     /translation="MSYSNRSERLQREIDDAIADGWRIESETPDRVVLVKRNLGSIGVH
                     LILAVLTGWWSFGVVNLVYGAYKYLNDSRRRVLRDGEACPECGVSVAPGASYCQNCGTD
                     LPGFEADAATATGTETTRTE"
     gene            complement(1874..3202)
                     /gene="truD"
                     /locus_tag="EPL01_RS17070"
     CDS             complement(1874..3202)
                     /EC_number="5.4.99.27"
                     /codon_start=1
                     /gene="truD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006185290.1"
                     /locus_tag="EPL01_RS17070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tRNA pseudouridine(13) synthase TruD"
                     /protein_id="WP_135826486.1"
                     /transl_table=11
                     /translation="MREAYPVEEAVGIEHFVSDSDGTGGRLRAAPEDFRVREVERFEAE
                     PADADAGAYPHLVIRATLREWDTNDFAKRLSDALGISRERVSWAGTKDKYAVTTQLFTL
                     RKIDESDLADVSIYDADVEVLGRSGRGLEFGDLAGNEFEIVVSDPENPENAEEIRSELE
                     DWAGEPLGVPNFFGQQRFGSRRPVTHEVGLHVVRGEWEEAVRAYVGNPYDTEPEGSQQA
                     RREVEEAFAERDWQAALEAVPPRLGFERSMLNALVESGGDSPADFRAALEAVPSNLQRL
                     FVNAAQSFAFNRILSERLARGLPFDRPVAGDVACFAEEVDGVTIPDPDREQRVTERRVE
                     TVARHCERGRAFVTAPLVGTETELAGGEPGEIEREVFEELDLAPEDFDLPGEFHSTGTR
                     RAILVRTDLEIEQNPLTFDFALPKGSYATVVLREFMKADPADE"
     gene            complement(3410..3748)
                     /gene="pth2"
                     /locus_tag="EPL01_RS17075"
     CDS             complement(3410..3748)
                     /EC_number="3.1.1.29"
                     /codon_start=1
                     /gene="pth2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007275742.1"
                     /locus_tag="EPL01_RS17075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="peptidyl-tRNA hydrolase Pth2"
                     /protein_id="WP_135826487.1"
                     /transl_table=11
                     /translation="MKQAIVARTDIGMGQGKLAAQVAHASLSAYEDTGTKARKQWKGEG
                     QKKVVLKADGETEIFELAEKARAEGLPNAVIRDAGHTQLDSGTVTALAVGPADDDLVDQ
                     VTGHLSLY"
     gene            3832..4437
                     /gene="dcd"
                     /locus_tag="EPL01_RS17080"
     CDS             3832..4437
                     /EC_number="3.5.4.13"
                     /GO_function="GO:0008829 - dCTP deaminase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006229 - dUTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="dcd"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008415898.1"
                     /locus_tag="EPL01_RS17080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="dCTP deaminase"
                     /protein_id="WP_135826488.1"
                     /transl_table=11
                     /translation="MILSDADILDRMEAGDLVVEPLDDPDLQIQPASVDLRLGREFLEF
                     KRTNIPCIHPDSEQEVSEYVTETKVEEDEEFILHPGDFVLGTTKERVEIPADLIAHVEG
                     RSSFGRLAVVVHATAGVVDPGYNGQITLELSNLGTAPVALKPDTRISQLIFTELRQAAE
                     RPYGSERGSKYQEQSGPQASRIGGDEEFGGDQKSGAER"
     gene            4434..5333
                     /locus_tag="EPL01_RS17085"
     CDS             4434..5333
                     /GO_function="GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006673147.1"
                     /locus_tag="EPL01_RS17085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thiamine-phosphate synthase family protein"
                     /protein_id="WP_135826489.1"
                     /transl_table=11
                     /translation="MRFAEEIVVEEFLPTVRSMLAEELRSRGLTQSEVADLLGISQSAV
                     SKYANGEVERNDRFLEDERVRNLVARISEGLAEETMSPVEALIEIEILVRQLEDRDLIA
                     EIHELEMPELSGHGGDFNVHDPDSELRVTERVRSSLRRGLTIVESASGFASLIPAVGSN
                     LCECTPDADGIDDVAGVPGRIFDVKGQATIPSEPEFGVSEHVASLLLAARRSGLDARAA
                     LNIRYDPDIVAALEEAGHGTAEFDAEYDDLDAVVGAALRENPDATVLYHTGGYGVEPIV
                     YILGEDAEAVAEIARGLL"
     gene            complement(5337..5585)
                     /locus_tag="EPL01_RS17090"
     CDS             complement(5337..5585)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EPL01_RS17090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="PRC-barrel domain containing protein"
                     /protein_id="WP_135826490.1"
                     /transl_table=11
                     /translation="MEFTEADEGASVFDADREKIGVVVEVRDGEAYVEPEPSLAEELKA
                     KLDWGSHEADEDAYALESNWIDEVEDGEILLRTRPQE"
     gene            5665..6264
                     /locus_tag="EPL01_RS17095"
     CDS             5665..6264
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006674394.1"
                     /locus_tag="EPL01_RS17095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_135826491.1"
                     /transl_table=11
                     /translation="MSLRERLENLGDVPLKGLRYSMWWIRKTFFVKPPTPGPSVVVSRS
                     ADGATRLLGRNYFDPGWELSYYFHGEVLNLRRVEYVEDHPTGIEWWQVHVRGYDHPDGV
                     ALTAHFEPEPSEHPNAHVEQVGLDVPRGMTALTDLLDREEVSYERDRIPRSASSVPSSS
                     TPASAPQNSDRAVTGRCPRRRSPRTSRIAGDNRPRW"
     gene            complement(6384..6626)
                     /locus_tag="EPL01_RS17100"
     CDS             complement(6384..6626)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007979861.1"
                     /locus_tag="EPL01_RS17100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PRC-barrel domain containing protein"
                     /protein_id="WP_135826492.1"
                     /transl_table=11
                     /translation="MTVAITEDEVDKAVVDADGTEVGTVVEVRHGAAHVSADEETVEEM
                     QTRLPEGGNDENTYAVGDESIADITDDRIVLDADE"
     gene            6857..7552
                     /locus_tag="EPL01_RS17105"
     CDS             6857..7552
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007275739.1"
                     /locus_tag="EPL01_RS17105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_135826493.1"
                     /sec_met_domain="PCMT (E-value: 1.6e-15, bitscore: 51.5,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATDATTAAQQFYGRWADLYDALARSTPGLGYLRSRAADTLALDP
                     GDTVVEMGCGTGANLPYLRERVGSEGRVVGVDFTQGMLARARERIDREEREGREEWRNV
                     HLVRGDATEIEFREPPDAILATFVVGMLADPEAAVNRWADQLAPGGRLALLDAAQTTRW
                     FGWPVNQAFRGLVVASSPTGMKGYERAPWSVLDDRVAAARRVLRARADETTHSEHALGV
                     VRITGGRID"
     gene            complement(7726..8550)
                     /locus_tag="EPL01_RS17110"
     CDS             complement(7726..8550)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005039173.1"
                     /locus_tag="EPL01_RS17110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF7001 family protein"
                     /protein_id="WP_246045733.1"
                     /transl_table=11
                     /translation="MTKVTLYRAPSSEARRASDCESETPTTVADADEIADWLRDLLGES
                     NDEEDIEVAVRDRFLDEHRTDDLAEQFAEARVLSPYERETGNTMLGIVRYEERALDHPE
                     REGGVLYDGVAVQRALNAAIPESERDLDHLHVALLDRAIGTWGDHDGRWHKRVNVLGQP
                     ALVSVPGLSEAPAKPEQYYKAKQKHAMLSGDAPPREVLENEVEGEFLVESDPRTTEALK
                     GYVLQAVHCWRTGEGFCEESGCRLSNPHRQPGVVEAQLREPEFCEAHAELYG"
     gene            complement(8568..9497)
                     /locus_tag="EPL01_RS17115"
     CDS             complement(8568..9497)
                     /EC_number="2.4.2.59"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008457789.1"
                     /locus_tag="EPL01_RS17115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sulfide-dependent adenosine diphosphate thiazole
                     synthase"
                     /protein_id="WP_135826494.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 3.6e-08, bitscore:
                     27.0, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEFDKFSEVGEADVTRAIGQEWTEEFMDFSDSDVIIVGGGPSGL
                     MAAKELSERGVQTMVVEKNNYLGGGFWLGGFLMNKVTVRDPAQHVLADLDVDFKQSRDS
                     DGLYVANGPEACSGLIKAACDAGAKMQNMTEFTDIVIREDHRVGGIVMNWTPVHALPRE
                     ITCVDPIAVEADLVIDATGHDGMAVSKLDERGVLDAPGIGDAKENATGMDKTGDDSYGA
                     PGHDSPGHDSMWVGKSEDAIVEHTGLVHDGLIVTGMATATTYGLPRMGPTFGAMLLSGK
                     RAAQCALDELEVDAEPVDMTTKAASADD"
     gene            9691..9843
                     /locus_tag="EPL01_RS21830"
     CDS             9691..9843
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EPL01_RS21830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_168215945.1"
                     /transl_table=11
                     /translation="MSVLDTDNAAESAKQSYDAEFDAVDTGSRDSPDGMKGEECAWSCA
                     SSTLC"
     CDS_motif       9691..9720
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSVLDTDNAA"
                     /locus_tag="EPL01_RS21830_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9721..9843
                     /prepeptide="core"
                     /locus_tag="EPL01_RS21830_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.20"
                     /molecular_weight="4073.3"
                     /monoisotopic_mass="4070.7"
                     /core_sequence="ESAKQSYDAEFDAVDTGSRDSPDGMKGEECAWSCASSTLC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSVLDTDNAA"
                     /leader_location="[9690:9720](+)"
                     /alternative_weights="4091.3"
                     /alternative_weights="4109.3"
                     /alternative_weights="4127.3"
                     /alternative_weights="4145.3"
                     /alternative_weights="4163.4"
                     /alternative_weights="4181.4"
     gene            10001..13183
                     /locus_tag="EPL01_RS17120"
     CDS             10001..13183
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007983023.1"
                     /locus_tag="EPL01_RS17120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_135826495.1"
                     /sec_met_domain="DUF4135 (E-value: 1.2e-78, bitscore:
                     259.0, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 3.8e-53, bitscore:
                     174.5, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPRLLTRQERREVAGRARTLHERLDGPPNEPGDDSPDGDRLLEAW
                     SDVFPDEQSFADRLAHAGLSEAEVRERAAATRWPADEPLPDWLAELESLLGHVVAAEFG
                     DDYPFDVPDETPFGDLLAPVAEYAHERLADSLSAGVSKNALGTTDTLGATDALDPAVEW
                     LFDRLELLTVRVLYVEFQSYLDSRSPELVEADPEEFADPPTENYRAFVEAMLDGGVTNL
                     CLEYPVLARRLTLVVGQWVAAVTELCQRLDRDRSALASRFDVDGSVTALRPLADDTHAG
                     GRAPVRVEFESGSAIYKPRDVGGGASFYTVLDRLDEQLETPSFRTPSFLRREEYGWMEP
                     VSYADPEDEAALRRYYERAGVLLGLGYALGLGDCQFENVIAAGEQPTVVDGETVFTPEI
                     GPGASLFSEGISRTVFESVLSTALLPYSSGDADTDRQVNIAGFGEVSGQQTLSGRTRPT
                     IEAANTDVMTVAPESPTVDGSHNTPTLDGEDRPPGDYAEAICAGFEQTYEAIRRLHDEG
                     RFFSETADEELLDGVETRVIFRPTNVYHAILRSSVARDPLRDGAWLTVEMDELAFPFFD
                     GWTDSKDLWPLCGAERRALRRFDVPRIASTPDGETAFHDGEELDLSLASSGYERARRRV
                     ASFDATDRERQTWMIRRALTTADDERPPAEPASVTDDRLRREAVESFDGVIEAVTGAPV
                     EDWMVMAGTDADLTLNPADESMYLGRSGVALTAAALHETTGESRYRRFTADLLGPVADE
                     IEAGVEGGGSSFSLGGTMGVGSVIYALSVVADLLGEARYRRLADEAVRTVTDDRIAADD
                     AFDVMDGSAGAILGLLAHYDRGGDSAALDRAVACGDRLLDGRVSVGGHRVWETNDETPL
                     TGFSHGSAGIAYALAELGAATGESRYVEAVREALAFEEALYDPDRSNWKHGWASDRFMD
                     RWCHGRSGIALARMGIADALGEEILPARRESALSATVESDPKGVDDLCCGNLGRVEALL
                     EAARRGDRPQSDAAELAGRCLARTDRDGTLALRGRTWVGPNPGFYKGLSGAAYTLLRVR
                     DPERLPCALLFE"
     gene            13292..13486
                     /locus_tag="EPL01_RS17125"
     CDS             13292..13486
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA]"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1255: cold-shock
                     DNA-binding domain protein"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004268146.1"
                     /locus_tag="EPL01_RS17125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cold-shock protein"
                     /protein_id="WP_135826496.1"
                     /transl_table=11
                     /translation="MANGTVDFFNDTGGYGFISTDDADDDVFFHMEDVGGPDLEEGTDI
                     EFDIEDAPKGPRATNVVRA"
     gene            complement(13661..14410)
                     /locus_tag="EPL01_RS17130"
     CDS             complement(13661..14410)
                     /EC_number="6.3.2.36"
                     /GO_function="GO:0016881 - acid-amino acid ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009487931.1"
                     /locus_tag="EPL01_RS17130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="4-phosphopantoate--beta-alanine ligase"
                     /protein_id="WP_135826497.1"
                     /transl_table=11
                     /translation="MTEIPDDHPRAQSLRTRHRIEEGVEKGITSKQGLIAQGRGEAYDY
                     LLGEQTTPSAERAERAAAAQLLLADHPVLSVNGNVAALVPAEMVELAEAVDADIEVNLF
                     NRTEERMAAIADHLREHGATDVKGLAADARIPGLEHERAKVDEDGIYDADVVVVPLEDG
                     DRAEALAEMGKTEIVVDLNPMSRSAQTAAIPIVDNIVRAVPNVTRHARELREQDSSREE
                     LEAIVAAFDREAALEEAERAIRQGELD"
     gene            complement(14441..15277)
                     /locus_tag="EPL01_RS17135"
     CDS             complement(14441..15277)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008577474.1"
                     /locus_tag="EPL01_RS17135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pantoate kinase"
                     /protein_id="WP_135826498.1"
                     /transl_table=11
                     /translation="MTDDSSRAFVPGHVTGFFSVHEADDPEQAGSRGAGLTLSEGVTVE
                     VEPAAETSMQLNDEPAAVEAVTRVLSDLGVEARVTATTDLPVGAGFGVSGAAALGTALA
                     ANRTFDCGRSENELVTIAHAAEVDAGTGLGDVVAQARGGVPIRLDPGAPEYGRMDGVAA
                     QSRVEYLTLGERSTEEVLAGNTDRLSEVGVDMLVRLVEEPTLSTLMDSSRKFAREADLL
                     TPEVEAVLEDVDEAGGEAAMAMLGETVFALGNGLSRAGYDAETCEVHSAGATLEMD"
     gene            complement(15515..16816)
                     /gene="aspS"
                     /locus_tag="EPL01_RS17140"
     CDS             complement(15515..16816)
                     /EC_number="6.1.1.23"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0004815 - aspartate-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006422 - aspartyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="aspS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006600624.1"
                     /locus_tag="EPL01_RS17140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aspartate--tRNA(Asn) ligase"
                     /protein_id="WP_135826499.1"
                     /transl_table=11
                     /translation="MEDRTYTADAEPGETATVAGWAHEIRDLGGIAFLIVRDTTGKIQV
                     KFEKDEMDDDLVETGINVNRESVVKVTGDVEEEERAPTGVEIVPESVEVIADADPELPL
                     DPSGKVDADLSTRLDNRTLDLRKDETKAIFEIRAEVLRSVREAFRELGSTEINTPKIVA
                     TGTEGGTELFPITYFGQEAFMNQSPQLFKQLMVGSGLERVFEIGPIFRAEEHNTPRHLN
                     EATSIDFESAFYDHQDAMDACEHVVKAAYEGVAENCQEELEALGYDDFEVPDGDFPRLS
                     YEEAIERINATGELDEQLVWGDDLPTEGEKALGEDVGSHYFITDWPSEIKPFYIKDHDD
                     DEQLSTGFDMMHPNMELVSGGQREHRYDKLVEGFEQQGLDPDAFEYYTKMFKYGMPPHA
                     GWGLGGERLIMTMLGLENIREAVLFPRDRQRLSP"
     gene            complement(16944..17570)
                     /locus_tag="EPL01_RS17145"
     CDS             complement(16944..17570)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018128924.1"
                     /locus_tag="EPL01_RS17145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_135826500.1"
                     /transl_table=11
                     /translation="MAGFDDAERERIRRQLRETGRDLFARYGLDKTTIGDLTTPAGIAN
                     GTFYRFYDSKEQLYFEILREEGERIATDLLAESFERVGDGKEELDPEEAIVAFLTLLCE
                     EIETNPLVRRLVADDDRSRLMAQFSDEELEAERAESLSYVVPYVERWQAEGRLREGDPE
                     VLAAAMGVVKFVAYRKDDFGDDEFYRAVRDVLIEAVAAGLTTRKG"
     gene            complement(17570..18367)
                     /locus_tag="EPL01_RS17150"
     CDS             complement(17570..18367)
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009376509.1"
                     /locus_tag="EPL01_RS17150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_135826501.1"
                     /transl_table=11
                     /translation="MLDIATYESERRIRGALVLSVLLAAMSLLFVALFPSISNSGADLD
                     AYMESLPPAVQAAFGASGTFSITTIEGFLAVELYQFFWLLLLGIYAAYLSGGLIAGDVE
                     RGRMDVLLAAPVSRARVVVEKFASLVPVVLAVNLVVGIAVFATVLAIGESISLADLAVV
                     HLLSVPYLLACGAIGLLLSVAFSESDAAKRAGLGAIFGLFLLDTVSESADLNWLGAISP
                     TRYYDPTAILVSGEYDWSGAVVLLAATVALVAVSAAWFRRKDI"
     gene            complement(18360..19301)
                     /locus_tag="EPL01_RS17155"
     CDS             complement(18360..19301)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007692085.1"
                     /locus_tag="EPL01_RS17155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_135826502.1"
                     /transl_table=11
                     /translation="MSAIETTGLTKYYGDTRGVEDLSLTVREGEVFGFLGPNGAGKTTA
                     IRTLLGFISPTGGSATLLGRDVTDEAALIEAKRRVGYLPSNPGLDEGTTGRRLIRYHAA
                     LKGDERSDELLEAFDPPIDREIGEYSTGNKQKLALVLSFMHDPDLVIMDEPTSGLDPLM
                     QERLYEFIEDEQARGTTFFFSSHVLSEVRKVCDRVGIIRNGELVAMEGVEELLDRSGKR
                     VHVSVEETLDPADFALAGVHDLDAGDGDASFMFTGEYDDLLDHLRNYRVRDLEIEEAPL
                     EDVFMKFYDDGPESESPPPETAAATAGGESDA"
     gene            complement(19827..20552)
                     /locus_tag="EPL01_RS17160"
     CDS             complement(19827..20552)
                     /EC_number="2.5.1.41"
                     /GO_function="GO:0047294 - phosphoglycerol
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007979592.1"
                     /locus_tag="EPL01_RS17160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphoglycerol geranylgeranyltransferase"
                     /protein_id="WP_135826503.1"
                     /transl_table=11
                     /translation="MTTSPWTDWDHIVKLDPDKTLAEGETFEDVCETGTDALEIGGTLD
                     MTQEKMQRVIDACAKYDVPLYQEPSNPAVVVDDDDLDGYLVPVVLNAGDIAWATGFHKE
                     WVKSSDVNWDRTTTEAYIIMNPDASVAELTSADCDQSPEDVAAYAEVAEQMYGQEIVYV
                     EYSGMYGDPDAVEAAADALEEATLFYGGGIHDYDSARTMAERADTIIVGDLVHDEGVEA
                     VRETVEAAQDAKAAAPESV"
     CDS             20554..20706
                     /gene="allorf_176054_176206"
                     /locus_tag="allorf_176054_176206"
                     /protein_id="allorf_176054_176206"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MRVNPRMRFNIFESTFYYGCECQRRSFSDELGRKPRPWKQIRFCM
                     HNVYA"
     CDS_motif       20554..20610
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MRVNPRMRFNIFESTFYYG"
                     /locus_tag="allorf_176054_176206_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       20611..20706
                     /prepeptide="core"
                     /locus_tag="allorf_176054_176206_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.10"
                     /molecular_weight="3806.4"
                     /monoisotopic_mass="3803.8"
                     /core_sequence="CECQRRSFSDELGRKPRPWKQIRFCMHNVYA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRVNPRMRFNIFESTFYYG"
                     /leader_location="[20553:20610](+)"
     CDS             complement(20579..20704)
                     /gene="allorf_176079_176204"
                     /locus_tag="allorf_176079_176204"
                     /protein_id="allorf_176079_176204"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MRIHCAYRTVFVSMAVAFGPVHRRMSAAGTRSRNKRWIRRC"
     CDS_motif       complement(20618..20704)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MRIHCAYRTVFVSMAVAFGPVHRRMSAAG"
                     /locus_tag="allorf_176079_176204_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(20579..20617)
                     /prepeptide="core"
                     /locus_tag="allorf_176079_176204_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.30"
                     /molecular_weight="1595.9"
                     /monoisotopic_mass="1594.9"
                     /core_sequence="TRSRNKRWIRRC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRIHCAYRTVFVSMAVAFGPVHRRMSAAG"
                     /leader_location="[20617:20704](-)"
                     /alternative_weights="1613.9"
     gene            20703..20900
                     /locus_tag="EPL01_RS17165"
     CDS             20703..20900
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008096053.1"
                     /locus_tag="EPL01_RS17165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="antitoxin VapB family protein"
                     /protein_id="WP_135826504.1"
                     /transl_table=11
                     /translation="MSTSIRVSNETKDKLSRLKRDDETWDEFLNRLTNEEEPINIGAWS
                     DDVADRAREAVESSRESFER"
     gene            20897..21289
                     /locus_tag="EPL01_RS17170"
     CDS             20897..21289
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005533617.1"
                     /locus_tag="EPL01_RS17170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PIN domain-containing protein"
                     /protein_id="WP_135826505.1"
                     /transl_table=11
                     /translation="MTFLDSSVIIDMLSGVDSTVEFVQEQGEPYFTSSLCVFEILDGVL
                     GSGSTDVVAARQDFDGVHALDLTDDIALEAARLQDQLLDDGQRMPTRDLLIAATARSTG
                     DHLVVADSDFETAILQSHIQVTNLSK"
     gene            21401..22168
                     /locus_tag="EPL01_RS17175"
     CDS             21401..22168
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EPL01_RS17175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_135826506.1"
                     /transl_table=11
                     /translation="MSEKEFIEFIPGIISSTTEDRHGHEISKSTLEKWAKELRDEKKTI
                     PFTFNHSSEPVGEWLDAQVLSHGDSAFLAGMVGIYSGNQDAVERLNDGEFGGLSIQGTT
                     YRNITENQFTSADEVISLSVEPSWSESIGGIIDQQGAGYRFEIQKSEVGLALFEIVIGN
                     IDGIIQALIMIHAYCTYQRKVFEEENQTEESSTRANIQLPDGTEVNLVENNAKEVIVQL
                     EESGYEVQINPEEAEQLSDTYQKAIKEKDAEDD"
     gene            complement(22172..22330)
                     /locus_tag="EPL01_RS21835"
     CDS             complement(22172..22330)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EPL01_RS21835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="WP_168215946.1"
                     /transl_table=11
                     /translation="MPHKARESDSGSDPESLDGIGAKTAEKLSDAGIEDIEELYRENIY
                     RLWVWRM"
ORIGIN
        1 tgaacagttc gtggccgatg accgcgagcg aggccgcgaa ccccgcaatc gcgcccggca
       61 gtcccgtgag ttggccgacc agcaccccca cacccgagag gagcggaatg gccgcgagga
      121 ccgcgtcgta gtggctgacc attgcgtaat taaatataat taccaccgcc aagaagcttg
      181 gggcttcgag ctggcagacc tcgtggcccc gacagcgatt tcgacgccga tagtcatagc
      241 tacgcggtgc ctaagtcggg ctacggtcgg ctttccggcg gtcgaaccgg cgctcgtttt
      301 actgtgaggc ggcctcggcc ctacccggcc gccctactgt gaggcggcct cggccctgcc
      361 cggccgccct actgtgaggc ggcctcggcc ctgcccggcc gccctactgc aactccgcct
      421 cggccagcgc gtcgttgagg tcggcccgga cgcgctcgcc gcgctcgcgg tccatcgcgg
      481 tcgtgacgac gcggttctcc tgcacgctcg aaccgtcccg aagaagcagt cggacgttgc
      541 cgttctcgtc ggcgcgggtc gccttcgccc ggacgccggt ccggcttccc gacccgccag
      601 cgtcgatggg acccggaata atcttcttga cgtgggggtg cccggcgacg gtctgaatcg
      661 ccgtccggcc cgcccggtcg ccgatgagcg tcgagtggct cccgccgagt ttctcggctg
      721 gcgaggcctc cacgacttcg agcgcccggt cgccccggcg cgcgaggacg gcctcgacgg
      781 ggtcctcggc ctcgtcgccg tcaccgacgc ggtagaacga gtggtggagc tggtcgcggg
      841 cggcccggag gacctcgcgg tcgcccgcgg cgtaaatctc ctcggggcgc ttgcgccgga
      901 cctcgtcggc gacccggccc gcgaagttcc ggagttcgac cacgcccgcc tcgccgccct
      961 cctcgggcgt ggtactcacg tcggtcttgc cgacgacctc ctcgtcgtct aacatcgtca
     1021 gggtcgcgtg gtcgcggtcg agttccagca ctacggcgtc ggcgttgggc gtccgacaga
     1081 ccagacagta gtcgcccggt cgttcgaggg gggacgcgca ttgccgacag tccatggtcg
     1141 ggggtaactc gccgccgaat ttaacctcgg tgctttggtt cgggggcctc actccgtccg
     1201 cgtggtctcg gttccagtcg ctgtcgcggc gtccgcttcg aatccgggga ggtcggtccc
     1261 gcagttctgg cagtagctcg cgcccggcgc gaccgagacg ccgcactcgg ggcaggcctc
     1321 gccgtcgcgg aggacccgac gtcgggagtc gttcagatac ttgtacgcgc cgtagacgag
     1381 gttgacgacg ccgaacgacc accagccggt caggaccgcc agaatcaggt ggacgccgat
     1441 gctcccgagg tttcgcttga cgaggacgac ccggtcgggc gtctcggact cgattcgcca
     1501 cccgtcggcg atggcgtcgt cgatttcgcg ctggaggcgc tcgcttctgt tgctgtagct
     1561 cattcgaagt cgggtacgac ggcttcgggg aaatggtttg aggctccccg agaagcgaag
     1621 ctaagaaatg aaaacaattc tttatacttt ctacagtagt gtcaaacaaa tgaataactg
     1681 tgtctagtga cgaaaccgat tcacctctgg atggtcactt gggacggtca tagaccacgg
     1741 gacgcgcccg ccgcgcgcgg aactgcgcgc ggcgggcggg gaggtacggg gcgcggtgcg
     1801 gtagtggagt ggtggcggtg cggtagtgga gtggtggcgg tgcggtggcg gagtggtcgc
     1861 gtagtggacg acatcactcg tctgcggggt ctgccttcat gaactcccgc aggacgacag
     1921 tcgcgtacga ccccttcggg agcgcgaagt cgaacgtcag cggattctgc tcgatttcga
     1981 ggtcagtcct gacaagaatc gcccgccggg tccccgtcga gtggaactcg cccggcaggt
     2041 cgaagtcctc gggggccaag tccaactcct cgaacacctc gcgctcgatt tcgcccggtt
     2101 cgccccccgc caactctgtc tcggtgccga ccagcggcgc ggtcacgaac gcccgacctc
     2161 gctcgcaatg gcgggcgacc gtctcgacgc ggcgctcggt gacgcgctgt tcgcggtcgg
     2221 ggtccggaat cgtcacgccg tctacctcct cggcgaagca ggccacgtcg cccgcgaccg
     2281 gacggtcgaa gggaagcccg cgagcgagtc gctcgctcag gattcgattg aaggcgaacg
     2341 actgggcggc gttgacgaag agtcgctgga ggttcgaggg cacggcctcc agcgccgcac
     2401 ggaagtccgc tggcgagtcg ccgccggact cgaccagcgc gttcagcatc gaacgctcga
     2461 atccgagccg cggggggacg gcctccagcg cggcctgcca gtcgcgctcc gcgaaggcct
     2521 cctcgacttc gcggcgggcc tgctggctcc cctcgggttc ggtgtcgtag ggattgccga
     2581 cgtaggcccg gacggcctcc tcccactcgc cgcggacgac gtggaggccg acctcgtggg
     2641 tgaccggccg ccgactgccg aatcgctgct gaccgaagaa gttggggacg ccgagtggtt
     2701 ctcctgccca gtcttcgagt tcgctccgaa tctcctcggc gttctccggg ttctcggggt
     2761 cgctgacgac gatttcgaac tcgttgccag ccaaatcgcc gaactccagt ccgcgcccgg
     2821 accgacccag cacctcgacg tcggcgtcgt agatggacac gtccgcgagg tccgactcgt
     2881 ctatcttccg gagggtgaac aactgagtcg tgacggcgta cttgtccttg gttccggccc
     2941 acgagacgcg ctcgcggctg attcccagcg cgtccgacag gcgcttggcg aagtcgttgg
     3001 tgtcccactc ccgcagggtc gcccggatta cgaggtgagg gtacgccccc gcgtcggcgt
     3061 cggcgggttc ggcctcgaac cgctcgacct cgcggacccg gaagtcctcg ggagcggccc
     3121 ggagtcgccc gccggtaccg tcgctgtcgc tgacgaagtg ttcgatgccg accgcctcct
     3181 cgactgggta cgcctcgcgc attcgtgttc gacggtgctt ggtggtcggg gtgcttgtat
     3241 ctggcttcct gcgatggacc ttcgaatttg gatttgtaga tacgattgag tacgccgaga
     3301 tggtagagtc ggacgacggg atagccaaga agaagactcc ttgaagcccc cgcccggtca
     3361 tccacccaga ctgtcggctg gttcgtcagc gcgccctctc gtcgggagtt cagtacagcg
     3421 agaggtggcc ggtcacttgg tccacgaggt cgtcgtctgc cgggccgacc gccagcgccg
     3481 tgaccgtgcc cgaatcgagt tgcgtgtggc cggcgtcccg gatgaccgcg ttggggaggc
     3541 cctcggcgcg ggccttctcg gcgagttcga agatttcggt ctcgccgtct gccttcagga
     3601 cgaccttctt ttggccctcg cccttccact gcttgcgggc cttggttccg gtgtcctcgt
     3661 aggccgacag cgaggcgtgc gcgacctgcg cggcgagttt tccctgcccc atgccgatgt
     3721 ccgtgcgggc gacgatagcc tgtttcatgc gacgaaatcc gagttgacat cgtatagatg
     3781 tactgctcgc ggaccgccac gctttacctc cctcccgcct ctgctacgag tatgatactc
     3841 tccgacgccg acatcctcga ccggatggag gctggcgacc tcgtagtcga accgctagac
     3901 gacccggacc tgcagattca gcccgcgagc gtggacctcc gcctcggccg ggagttcttg
     3961 gagttcaagc gcaccaacat cccctgcatc caccccgaca gcgagcagga ggtctccgaa
     4021 tacgtcaccg agacgaaagt cgaggaggac gaggagttca tcctccaccc cggcgacttc
     4081 gtgctgggca cgaccaaaga gcgcgtcgag attccagcag acctcatcgc tcacgtcgag
     4141 ggtcggtcgt cgttcggccg cctcgcggtc gtggtccacg ccacggcggg cgtggtagac
     4201 cccggataca acggccaaat aacgctcgaa ctctcgaatc tcgggaccgc gccggtcgcg
     4261 ctcaagcccg acactcgcat ctcacagctc atcttcaccg agttgcggca ggccgccgag
     4321 cgaccctacg gttccgagcg cgggtcgaag tatcaagaac agtccgggcc gcaggcctcc
     4381 cgcatcggcg gcgacgagga gttcggcggc gaccagaaat cgggtgcaga gagatgaggt
     4441 tcgccgagga gatcgtcgtc gaggagtttc tccccaccgt gcgctcgatg ctggccgagg
     4501 aactccgcag tcgcggcctg acccagagcg aggtcgccga cctgctgggc atcagccaga
     4561 gcgcggtctc gaagtacgct aacggcgagg tcgagcgaaa cgaccggttc ctcgaagacg
     4621 agcgcgtccg gaacctcgtc gcgcgaatca gcgagggact ggccgaggag acgatgagtc
     4681 cggtcgaggc gctcatcgaa atcgagattc tcgtccggca actcgaagac cgggacctca
     4741 tcgccgagat tcacgagttg gagatgcccg aactctcggg tcacggcggc gacttcaacg
     4801 tccacgaccc agacagcgaa ctccgggtga cagagcgcgt ccggtcgtcg ctccggcggg
     4861 gcctgaccat cgtggaaagc gccagcgggt tcgcctcgct catcccggcg gtcgggtcga
     4921 acctctgtga gtgtacgccc gacgccgacg gtatcgacga cgtggcgggc gtgcccggcc
     4981 gaatcttcga cgtgaagggg caggccacca tcccctcgga acccgagttc ggcgtgagcg
     5041 aacacgtcgc ctcgctcctg ctggccgcca gacggagcgg actggacgcc cgcgccgcgc
     5101 tgaacattcg ctacgacccc gacatcgttg cggcgctgga agaagcgggc cacgggaccg
     5161 ccgagttcga cgccgagtac gacgacctcg acgcggtggt cggcgcggcc ctccgagaga
     5221 acccggacgc gaccgtcctc taccacaccg gcggctacgg cgtcgaaccc atcgtctaca
     5281 ttctcggcga ggacgccgag gcggtcgccg aaatcgctcg cggactactc tgagttttac
     5341 tcctgcggcc gagtccgcag cagaatctcg ccgtcctcga cttcgtctat ccagttcgac
     5401 tcgagcgcgt aggcgtcctc gtcggcctcg tggctccccc agtcgagttt ggccttgagt
     5461 tcctcggcca ggctgggttc cggttcgacg taggcctcgc cgtcgcggac ctcgacgacc
     5521 acgccgatct tctcgcggtc ggcgtcgaac acggacgcgc cctcgtcggc ttcggtgaac
     5581 tccatgccac ctgttcgacg cctgcggtca tgacggctac ggccccgcga aatattaata
     5641 attaattata atgtttactg tggcatgtcg cttcgagaac gactggagaa cctcggcgac
     5701 gtgccgctga aaggactccg atactcgatg tggtggattc ggaagacgtt cttcgtgaaa
     5761 ccgccgacgc cggggccgtc ggtggtcgtg agtcggtctg ccgacggggc cacgcgactg
     5821 ctcggtcgga actacttcga cccgggatgg gagctgtcgt actacttcca cggcgaggtg
     5881 ctgaacctcc ggcgggtcga gtacgtcgag gaccacccga ccggcatcga gtggtggcag
     5941 gtccacgtcc gcggatacga ccaccccgac ggcgtggcgc tgaccgccca cttcgaaccc
     6001 gaaccgagcg agcatcccaa cgcccacgtc gagcaagtcg gtctcgacgt gccgcgcggg
     6061 atgaccgcgc tcacggacct gctggaccgc gaggaggttt cctacgagcg tgaccgaatt
     6121 ccgcggtcgg cctcgtcggt cccgtcctcc tcgacgcccg cgtcggcccc tcagaactcc
     6181 gaccgggcgg tcacgggcag gtgtccgaga cgccgctctc cgaggacttc tcgaatcgcc
     6241 ggggacaacc gaccgaggtg gtaacgcgaa ttagaaaaga acagagatag atgttcctaa
     6301 ggagtattta gatttcctaa ggatatattt ctatttcttt cctgaagaaa tagaatcctt
     6361 ccgcggcgac cgactcccac gccctactcg tcggcgtcca gcacgattcg gtcgtcggtg
     6421 atgtcggcga tgctctcgtc gccgaccgcg taggtgttct cgtcgttgcc gccctctggg
     6481 agtcgagtct gcatctcctc gacggtctcc tcgtcggcgc tgacgtgggc cgcgccgtgg
     6541 cggacctcga ccacggtccc gacttcggtc ccgtcggcgt ctacgaccgc tttgtccacc
     6601 tcgtcctctg tgattgcgac cgtcatgcgg cgtaggtacg gcttcgcggt tcttcaggtc
     6661 ggtggccgcg atgagaaacc gtactcggtg aaagcgtcgg gataggaacg gggacctcga
     6721 aagccctcgc gctcagcacg caggaagaga cgagacaaca acatcctcga aagccctcgc
     6781 gcggttcggt cacgaagcgg cgtcagttcc gccctcccgc cccatccatt ttggtcccgg
     6841 gcgtcgtcgt cccggcatgg cgaccgacgc gacgacggcg gcgcagcagt tctacgggcg
     6901 gtgggcagac ctctacgacg cgctggcacg ttcgacgccc ggcttgggct atctgcggag
     6961 tcgggccgcc gacacgctcg cactcgaccc cggcgacacg gtggtcgaga tgggatgtgg
     7021 cacgggcgcg aacctgccct acctccgaga gcgagtcggc tccgagggcc gggtcgtcgg
     7081 cgtggacttc acgcagggga tgctggcacg cgctcgggag cgaatcgacc gcgaggagcg
     7141 agagggccgc gaggagtggc ggaacgtcca cctcgtgcga ggagacgcca ccgaaatcga
     7201 gttccgagag ccaccggacg ccatcctcgc caccttcgtc gtcgggatgc tcgccgaccc
     7261 cgaggcggcc gtgaaccggt gggccgacca actcgcgccc ggcggtcgcc tcgcgctcct
     7321 cgacgcggcc cagacgacgc ggtggttcgg gtggccggtg aatcaggcgt ttcgggggct
     7381 ggtcgtggcc tcgtcgccga ccggcatgaa gggctacgag cgcgcgccgt ggtcggtgct
     7441 ggacgaccga gtggccgcgg cccggcgtgt gctcagagcg cgcgccgacg agacgaccca
     7501 cagcgaacac gccctcggcg tggttcggat taccgggggg cgaatcgact gagagcggcg
     7561 atttcgggag aatccagttt gggtagtggt tggggatacc agcccccgac gaccggtctc
     7621 ttgccagagt cgctatgtcg ccgttttggg ggtcgcaggc aaaaatggta aacggcggcc
     7681 atcgaacaga ctcgcctgtc agaaagcgcg tcggaggagt agctgtcacc cgtacaactc
     7741 ggcgtgggcc tcgcagaact ccggttcgcg caactgggcc tcgaccacgc ccggctgtcg
     7801 atgcgggttc gagagccgac agcccgactc ctcgcagaag ccctcgccgg tccgccagca
     7861 gtggaccgct tgcaggacgt agcccttcag ggcctcggtc gtccgggggt ccgactcgac
     7921 cagaaactca ccctcgactt cgttttcgag gacctcgcgg ggcggcgcgt cgccggagag
     7981 catggcgtgc ttctgttttg ctttataata ctgctcgggc ttggcgggcg cttcggagag
     8041 gcccggcacc gagaccagcg cgggctggcc gaggacgttg acgcgcttgt gccaccgacc
     8101 gtcgtggtca ccccacgtgc cgatagcccg gtccagcagc gcgacgtgga ggtggtcgag
     8161 gtcgcgctcg ctctcgggaa tcgctgcatt cagcgcgcgc tggaccgcaa cgccgtcgta
     8221 gaggacgccg ccctcgcgct cggggtggtc gagggcgcgc tcctcgtacc ggacgatgcc
     8281 gagcatcgtg ttgcccgtct cgcgctcgta gggcgagagg acgcgggcct cggcgaactg
     8341 ctcggcgagg tcgtcggttc gatgctcgtc caaaaaccgg tcgcggaccg cgacctcgat
     8401 gtcctcctcg tcgttgctct cgccgaggag gtcgcggagc cagtccgcga tttcgtcggc
     8461 gtccgcgacg gtggtcggcg tctcggactc gcagtccgag gctcgtcgag cttcgctcga
     8521 cggcgcgcga tacagcgtga ccttggtcat gtctgactgg atggtcctca gtcgtccgcc
     8581 gaggccgcct tcgtggtcat gtccaccggc tcggcatcga cttccaactc gtcgagggcg
     8641 cactgggcgg cgcgcttgcc cgacaggagc atcgcgccga aggtcggtcc catccgcggc
     8701 agaccgtagg tcgtcgcggt cgccatgccg gtgacgatga ggccgtcgtg aaccaatcca
     8761 gtgtgttcca cgatggcgtc ctccgatttg ccgacccaca tcgagtcgtg gccgggcgag
     8821 tcgtggcccg gcgcgccgta ggagtcgtcg ccggtcttgt ccatgccggt cgcgttctcc
     8881 ttggcgtcgc cgattccggg ggcgtcgagg acgccgcgct cgtccagttt cgagaccgcc
     8941 atgccgtcgt ggccggtcgc gtcgatgacg aggtcggcct cgaccgcgat ggggtcgacg
     9001 caggtaatct cgcggggcag ggcgtggacc ggcgtccagt tcatcacgat gccgccgacg
     9061 cggtggtcct cccgaatcac gatgtcggtg aactcggtca tgttctgcat cttcgcgcca
     9121 gcgtcgcagg ccgccttgat gaggcccgaa caggcttccg gaccgttagc gacgtagagg
     9181 ccgtcgctgt cgcgggactg cttgaagtcc acgtcgaggt cggccagcac gtgctgggcc
     9241 gggtcgcgca ccgtgacctt gttcatgagg aagccgccga gccagaaccc gccgcccaga
     9301 tagttgttct tctcgacgac catcgtctgg acgccgcgct cggagagttc cttcgcggcc
     9361 atcaggccgg agggaccgcc gccgacgata atcacgtcgg agtccgagaa gtccatgaac
     9421 tcctcggtcc actcttgtcc gattgcgcgg gtcacgtccg cctcacccac ctcgctgaac
     9481 ttgtcgaatt cgctcataca actcggtagt atcacggagt ggttgaaagg ggttgcgaaa
     9541 tggattcggt gtacttcctc cgcgcagagt cgaaatcggt cgcgtgaacg tatctccggc
     9601 gaccacgggg cgttcgagta ttttcaactt ggtgttggac ctaattatct agtgagaaga
     9661 gttatgttat caactaccat gtggtaatgt atgtcggtgc ttgatactga caacgcggca
     9721 gaatcggcaa agcaatcgta cgacgcggag ttcgacgcgg tagacacggg gtcgcgcgac
     9781 tcgccggacg gcatgaaggg cgaggagtgc gcgtggtcct gcgccagttc gacgctgtgc
     9841 tagcaggctg aaccggcgca attctcggtc ggcgcgtccg cgggtcggcg atagaacctc
     9901 ggacacgcct gatttacttc cgtcactgac cgaccagaga gtgacgacag tcgatgtgac
     9961 tcgctgactc gtcagcaccg acaccgacaa cgcaccagag atgccacgac tactcacccg
    10021 acaggaacgg cgagaggtcg ccgggcgcgc ccggaccctc cacgaacggt tggacggacc
    10081 gccgaacgaa ccgggcgacg actcgcccga cggagaccga ctgctcgaag cgtggagcga
    10141 cgtcttcccg gacgagcaat cgttcgccga ccgcctcgcc cacgccggac tgtccgaggc
    10201 cgaggtccgc gagcgagcgg cggcgactcg ctggcccgcc gacgaaccgc ttccggactg
    10261 gctcgccgaa ctcgagtcgc tcctcggcca cgtcgtcgcc gccgagttcg gcgacgacta
    10321 ccccttcgac gtccccgacg agacgccgtt cggcgacctc ctcgcgccgg tcgcggagta
    10381 cgctcacgag cgactggccg attcgctgtc tgcgggcgtc tcgaagaacg cgctcgggac
    10441 gaccgacacg ctcggcgcga cggacgcgct ggacccggcg gtcgagtggc tgttcgaccg
    10501 cctcgaactc ctgaccgtgc gcgtcctcta cgtcgagttc cagagctacc tcgactcgcg
    10561 cagtcccgaa ctggtcgagg ccgaccccga ggagttcgcc gacccgccga ccgagaacta
    10621 ccgggcgttc gtcgaggcca tgctcgacgg cggcgtcacg aacctctgtc tggagtaccc
    10681 ggtcctcgcg cgccgactga cgctggtcgt cggccagtgg gtcgccgccg tgacggaact
    10741 gtgccagcga ctcgaccggg accgctcggc gctggcctcg cgcttcgacg tggacgggtc
    10801 ggtgaccgcg ctccgaccgc tcgccgacga cacccacgcc gggggtcgcg cgccggtccg
    10861 ggtcgagttc gagtccgggt ccgcaatcta caagcccaga gacgtgggcg gcggagcgag
    10921 cttctacacc gtcctcgacc gattggacga gcagctcgaa actccgtcct tccggacgcc
    10981 gagttttctg cgccgcgagg agtacgggtg gatggaaccg gtttcgtacg ccgaccccga
    11041 ggacgaggcc gcgctccggc gctactacga gcgcgccggg gtgctgttgg gactgggcta
    11101 cgcgctcggt ctcggcgact gccagttcga gaacgtaatc gccgccgggg agcagccgac
    11161 cgtcgtggac ggcgagaccg tcttcacgcc cgaaatcggc cccggcgcgt cgctgttctc
    11221 ggagggaatc agccggaccg tcttcgagtc cgtgctgagt accgcgttgc tcccctactc
    11281 gtcgggggac gcggacaccg accggcaggt gaacatcgcc gggttcggcg aggtcagcgg
    11341 ccaacagacg ctctcgggcc ggacgcgccc gaccatcgag gcggccaaca ccgacgtgat
    11401 gacggtcgcg ccggagtcgc ccacggtgga cgggagccac aacacgccga ccctcgacgg
    11461 cgaggaccga ccgccgggcg actacgccga ggcaatctgt gcggggttcg agcagaccta
    11521 cgaggcgatt cgccgactcc acgacgaggg ccggttcttc tcggaaaccg ccgacgagga
    11581 gttactcgac ggcgttgaga cgcgggtcat cttccggccg acgaacgtct accacgccat
    11641 cctccggtcg agcgtggcgc gcgacccgct tcgggacggg gcgtggctca ccgtcgagat
    11701 ggacgaactg gccttcccct tcttcgacgg gtggaccgac tcgaaggacc tctggccgct
    11761 ctgtggggcc gagcggcgcg cgctccggcg gttcgacgtg ccgcgaatcg cctcgacgcc
    11821 ggacggcgag accgccttcc acgacggaga ggagttggac ctctcgctgg cgtcctcggg
    11881 ctacgagcgc gctcgccgcc gggtggcgtc gttcgacgcg accgaccggg agcgccagac
    11941 gtggatgatt cgccgggcgc tgacgaccgc cgacgacgag cgaccgcccg ccgaaccggc
    12001 gtccgtgacc gacgaccgac tccggcgcga ggcggtcgag tcgttcgacg gcgtcatcga
    12061 ggccgtcacc ggcgcgccgg tcgaagactg gatggtgatg gcggggaccg acgccgacct
    12121 cactctgaac ccggcagacg agtcgatgta tctcggtcgg agcggagtcg cgctcaccgc
    12181 ggcggcgctc cacgagacga ccggcgagtc gcgctaccgg cggttcaccg ccgacctgct
    12241 cggcccggtg gccgacgaaa tcgaggcggg cgtcgagggc ggcgggtcgt cgttctcgct
    12301 cgggggcacg atgggcgtcg ggtcggtcat ctacgccctc tcggtggtcg cggacctcct
    12361 cggtgaggcg cgctaccgcc gactggccga cgaggcggtc cggaccgtga ccgacgaccg
    12421 catcgcggcc gacgacgcct tcgacgtgat ggacgggagc gccggggcga ttctcggact
    12481 gctggctcac tacgaccggg gcggcgactc ggcggcgctc gaccgcgccg tcgcctgcgg
    12541 ggaccgactc ctcgacgggc gcgtctcggt cggcggccac cgcgtctggg agaccaacga
    12601 cgagacgccg ctgacggggt tctcccacgg gtcggcgggc atcgcctacg cgctggccga
    12661 actgggggcc gcgaccggcg agtcgcgcta cgtcgaggcg gtccgcgagg cgctcgcgtt
    12721 cgaggaggcc ctctacgacc ccgacaggtc caactggaag cacgggtggg cctccgaccg
    12781 gttcatggac cggtggtgtc acggtcggtc gggcatcgcg ctggcccgga tgggcatcgc
    12841 cgacgcgctc ggcgaggaga tactcccggc ccggcgcgag tcggcgctgt cggcgacggt
    12901 cgagtccgac ccgaagggcg tggacgacct ctgctgtggc aacctcggcc gagtcgaggc
    12961 gttgctggag gcggcccgcc ggggcgaccg accgcagtcc gacgcggccg aactggcggg
    13021 tcggtgcctc gcgcggacgg accgcgacgg gacgctcgca ctccgcgggc ggacgtgggt
    13081 cggccccaat ccggggttct acaagggcct ctccggggcg gcatacaccc tcctgcgggt
    13141 ccgagacccc gagcgactcc cgtgtgcgct gttgttcgaa taaccacttg cgaccacttt
    13201 gacggcgatt ttccggcgca gaatcgacgg ggtccgtgat accgcgaccc tcggaagtgt
    13261 tatccgtgga cgggtcctgt gtataattgt aatggcaaac ggtactgttg atttcttcaa
    13321 cgacactggc ggctacggtt tcatctcgac tgacgacgcg gacgacgacg tgttcttcca
    13381 catggaggac gttggcggcc ccgacctcga agagggaact gacatcgaat tcgacatcga
    13441 agacgccccc aagggccccc gcgcgacgaa cgtcgtccgc gcgtaagtcg aaaactactc
    13501 gctttcgagc gacactttaa cttcgctttt tacgacgcta cttcccgccg agcgcaagcg
    13561 ccggaatcgc aatactgagc gaaagaattc agattaattt tcaaacacaa taaaatattg
    13621 ctaaaagttg tctatagaat tcttttccgc cctgccgaag tcagtccaac tcgccctgcc
    13681 gaatcgcccg ctccgcctcc tccagcgccg cctcgcggtc gaacgccgcg acgattgcct
    13741 ccaactcctc gcgcgaggag tcctgctctc gcaactcccg ggcgtgtctc gtcacgttcg
    13801 gcaccgctcg cacgatgttg tccacgatcg gaatcgcggc ggtctgggcc gaccgggaca
    13861 tcggattcag gtccacgacg atttcggtct tgcccatctc ggccagcgcc tccgcgcggt
    13921 cgccgtcctc cagcgggacc acaaccacgt cggcgtcgta gattccgtcc tcgtcgacct
    13981 tggcgcgctc gtgttccaac cccggaatcc gggcgtcggc cgcgaggccc ttcacgtccg
    14041 tcgcgccgtg ttcccgcagg tggtcggcga tggccgccat tcgctcctcg gtccggttga
    14101 acaggttcac ttcgatatcg gcgtccacgg cctcggccaa ctcgaccatc tcggcgggga
    14161 cgagcgcggc gacgttgccg ttgaccgaga ggacggggtg gtcggccaga agcagttgcg
    14221 cggcagccgc cctctctgct cgctcggcgc tcggagtcgt ctgctccccg aggaggtagt
    14281 cgtaggcctc gccgcggccc tgtgcgatga ggccctgctt gctggtgata cccttctcga
    14341 cgccctcctc gattcggtgg cgggtccgaa gcgactgggc tcgggggtgg tcgtcgggaa
    14401 tctcggtcat gggggttact ccgcgggggg ccgggaaaaa tcagtccatc tccagcgtcg
    14461 cgcccgccga gtggacctcg caggtctcgg cgtcgtagcc cgcccgcgac aggccgttgc
    14521 cgagcgcgaa gacggtctcg ccgagcatcg ccatcgcggc ctcgccgccc gcctcgtcaa
    14581 cgtcttcgag gaccgcctcg acttcgggcg tcagcaagtc ggcctcgcgg gcgaacttcc
    14641 gcgaggagtc catcagcgtc gataaggtcg gctcctctac gaggcggacc agcatgtcca
    14701 cgccgacctc cgagaggcgg tcggtgttgc ccgcgaggac ctcctcggtc gagcgctcgc
    14761 ccagcgtcag atactccacg cggctctggg cagccacccc gtccatccgg ccgtactccg
    14821 gcgcgccggg gtcgagtcga atcgggacgc cgccgcgggc ctgtgccacc acgtcgccga
    14881 gtccggtccc ggcgtcgacc tccgcggcgt gggcgatggt cacgagttcg ttctccgagc
    14941 gcccgcagtc gaaggtccgg ttggccgcca aggcggtccc gagcgcggcg gcacccgaga
    15001 cgccgaagcc agcgcccacg ggcaggtcgg tcgtggcggt cactcgcgcc tcgacgccga
    15061 ggtccgaaag cactcgggtc accgcctcga cggcggcggg ttcgtcgttc aactgcatcg
    15121 aggtctcggc ggcgggttcg acctcgacgg tcacgccctc cgagagggtc aggcccgcgc
    15181 cgcgcgaacc ggcctgctcg gggtcgtcgg cctcgtggac gctgaagaag ccggtgacgt
    15241 ggcccggcac gaacgcccgc gacgagtcgt cggtcatact ctggcctttc gagtcacgcc
    15301 gtataacctt tataatctgg gccgagcgcc gacgccgcta cacgttcgga ggagactcga
    15361 aactgcaaac gaatcgaatc ggcgaggcgt cagcttacgg cgagagacgc tgacggtctc
    15421 gcgggaacac cggaagacgg tccgggatgc tcactacgtt gcgcttccgg gcctgcgact
    15481 tccgagcgcc cgcgcgagac agggacgccg tcgcctacgg cgagagacgc tgacggtccc
    15541 gcgggaacag cacggcctcg cggatgttct ccagtccgag catcgtcatg atgaggcgct
    15601 cgccgccgag gccccatccg gcgtggggcg gcatgccgta cttgaacatc ttggtgtagt
    15661 actcgaaggc gtcggggtcc agaccctgct gttcgaagcc ttcgacaagc ttgtcgtagc
    15721 ggtgttcacg ctggccgccg gagacgagtt ccatgttcgg gtgcatcatg tcgaacccgg
    15781 tcgagagctg ctcgtcgtcg tcgtggtcct tgatgtagaa gggcttgatt tcgctgggcc
    15841 agtcggtgat gaagtagtgg gaaccgacgt cctcgccgag ggccttctcg ccctcggtgg
    15901 gcaggtcgtc gccccagacc aactgctcgt cgagttcgcc cgtggcgttg atgcgctcga
    15961 tggcctcctc gtagctcagt cgcgggaagt cgccgtccgg gacctcgaag tcgtcgtagc
    16021 cgagtgcctc cagctcctcc tgacagttct cggcgacgcc ctcgtaggcc gccttgacga
    16081 cgtgttcgca ggcgtccatc gcgtcctgat ggtcgtagaa ggcgctctcg aagtcgatag
    16141 aggtcgcctc gttgaggtga cggggcgtgt tgtgctcctc ggcgcggaaa atcggaccga
    16201 tttcgaagac ccgctccaga ccggagccga ccatcagctg tttgaacagc tggggcgact
    16261 ggttcatgaa cgcttcctga ccgaagtacg tgatggggaa cagttcggtg ccgccctcgg
    16321 tgcccgtcgc aacgattttc ggcgtgttga tttcggtcga gccgagttcg cggaaggcct
    16381 cgcggaccga gcgcaggacc tcggcgcgaa tctcgaagat ggccttggtc tcgtccttcc
    16441 ggaggtcgag ggtgcggttg tcgaggcgcg tcgagaggtc ggcgtccacc ttgcccgagg
    16501 ggtccagcgg gagttcgggg tcggcgtcgg cgatgacctc gaccgactcg gggacgattt
    16561 cgacgccggt cggggcgcgc tcctcttcct ctacgtcgcc cgtgaccttc acgacgcttt
    16621 cgcggttgac gttgatgccg gtctccacga ggtcgtcgtc catctcgtcc ttctcgaact
    16681 tgacctgaat cttgccggtc gtgtcgcgga cgatgaggaa tgcgatgcca ccgaggtctc
    16741 gaatctcgtg ggcccaaccc gcgaccgtcg cggtctcgcc gggttcggcg tcggccgtgt
    16801 acgttcggtc ttccatgggt ctgagtttct gcggcgttct cttaaacgcc gtcatttcgt
    16861 cggaaggaaa tcgctcgcaa acccacgtat gctttccgga agtgtgcgga ggagtctcac
    16921 tcgctcccca cccgttcgct ctctcaccct ttccgggtcg tcagtcccgc cgccaccgcc
    16981 tcgatgagca cgtctcggac cgcccgatag aactcgtcgt cgccgaagtc gtccttccgg
    17041 taggcgacga acttcacgac gcccatcgcg gccgcgagga cctcggggtc gccctcgcgg
    17101 agtcggccct cggcctgcca gcgctcgacg tagggcacga cgtagctcag cgactcggcg
    17161 cgctcggctt ccaactcctc gtcgctgaac tgggccatca ggcgcgagcg gtcgtcgtcc
    17221 gcgaccagtc ggcggaccag cgggttagtc tcgatttctt cacagaggag ggtgaggaag
    17281 gcgacgatgg cctcctcggg gtcgagttct tctttaccat ccccgacacg ctcgaaggac
    17341 tcggcgagga ggtcggtggc gattcgttcg ccctcctcgc ggagaatctc gaagtagagc
    17401 tgttctttcg agtcgtagaa ccggtagaag gtcccgttgg cgatgcccgc gggagtagtg
    17461 aggtcgccga tggtggtctt gtcgaggccg tagcgcgcga acaggtcccg gccggtctct
    17521 cgaagttgtc ggcggatgcg ctcgcgctcg gcgtcgtcga acccggccat cagatgtcct
    17581 tcctccggaa ccacgcggcg ctgaccgcga ccagcgcgac tgtcgccgcg aggaggacga
    17641 ccgcacccga ccagtcgtac tcgccggaga cgagaatcgc ggtcgggtcg tagtaccggg
    17701 tcgggctaat cgcgcccagc cagttcaggt cggccgactc gctgaccgta tccagcagga
    17761 acaggccgaa gatggccccg agaccggcgc gcttggccgc gtcggactcg gagaacgcga
    17821 ccgacagcag gagaccgatt gctccgcagg cgagcaggta gggcacggac agcaggtgga
    17881 ccaccgcgag gtcggccagc gagatggact cgccgatggc gaggacggtg gcgaagactg
    17941 ctatccccac cacgaggttg accgcgagga cgaccgggac gagcgaggcg aacttctcga
    18001 ccacgacccg cgctcgggag accggcgcgg ccagcaacac gtccatccga ccgcgctcca
    18061 cgtcgccagc aatcaggccg cccgagaggt aggcggcgta gatgccgagc aggagcaacc
    18121 agaagaactg gtagagttcg accgccagaa agccctcgat ggtagtgatg gagaaggtcc
    18181 cggacgcgcc gaacgccgcc tgcaccgcgg gcggaagact ctccatgtag gcgtccaagt
    18241 ccgcccccga gttcgaaatc gaggggaaca gcgcgacgaa cagcagggac atcgcggcca
    18301 gcaggacgga caggacgagc gcgccccgaa tccggcgctc ggactcgtag gtggcgatgt
    18361 caagcatcgg actcgcctcc ggcggtcgcc gccgcggtct cgggcggcgg ggactcgctc
    18421 tccggcccgt cgtcgtagaa cttcatgaac acgtcctcga gcggggcctc ctcgatttcg
    18481 aggtcccgaa cgcggtagtt ccggaggtgg tcgagcaggt cgtcgtactc gccggtgaac
    18541 atgaacgagg cgtcgccgtc gcccgcgtcg aggtcgtgga cgccagcgag ggcgaagtcc
    18601 gccgggtcga gcgtctcctc gacgctgacg tggacgcgct tgccgctccg gtcgagcaac
    18661 tcctcgacgc cctccatcgc cacgagttcg ccgttccgga tgatgcccac gcggtcgcag
    18721 accttccgga cctcgctcag gacgtggctg gagaagaaga aggtggtccc gcgggcctgc
    18781 tcgtcctcga tgaactcgta gagccgttcc tgcatcaggg ggtccaaccc ggaggtcggt
    18841 tcgtccataa tcacgaggtc cgggtcgtgc atgaacgaaa gcaccagcgc cagcttctgc
    18901 ttgttgcccg tcgagtactc gccgatttcg cggtcgattg gcgggtcgaa cgcttcgagg
    18961 agttcgtcgg accgctcgtc gcccttgagc gcggcgtggt agcgaatcag ccgtcgcccg
    19021 gtggtgccct cgtcgaggcc ggggttgctc ggcaggtagc cgacccgccg cttggcctcg
    19081 atgagcgccg cctcgtcggt cacgtcccgg ccgaggaggg tcgccgaccc gccggtcggg
    19141 gagatgaacc ccagcagggt ccggatggcc gtggtcttgc ccgcgccgtt ggggccgagg
    19201 aagccgaaga cctcgccctc tcgcaccgtc agcgagaggt cctcgactcc tcgggtgtcc
    19261 ccgtagtact tcgtcaggcc ggtcgtctcg attgcgctca ttcctaaatg ttcgttccgt
    19321 gaatagatga atagttcggt tatccgttca cgagacgcgg aatcgcacag gagagtcgtt
    19381 ggaatcggcg aaaccggccg aaggtgtcag aaccgagagg ggcgcttact gtccaccgtc
    19441 gagaacgctt gctggaactg ccgaggtttc gtgcaggtca tccaccgaca gatttcggcc
    19501 ggtgaaacag accacctgcg gtcctcggcg gactgaaagg gcgagcgcgg ttcgcgcacc
    19561 gcgtggtcgt ctcagcgacc cctatccgaa gtcgggcggt gcggagagac ttcggatatg
    19621 tcgctgaacg accgcgaacc gcgcgagggc tttcgaggac actgctgtct cacctgcttc
    19681 tacggtttcg agtacgagga ctttcgaggt cgaagtcacg gcctcgtcgg tcccctctcg
    19741 aacagacaaa cgaaaacaat gctaaaactg attcaaatga tgcttaaatg cagaaagagt
    19801 tggttttgtc cggagaaaaa agcgtctcag accgattcgg gcgcggccgc tttcgcgtcc
    19861 tgtgcggcct cgacggtctc gcgcaccgcc tcgacgccct cgtcgtggac gaggtcgccg
    19921 acgatgatgg tgtcggcgcg ctcggccatc gtccgggccg agtcgtagtc gtggatgccg
    19981 ccgccgtaga atagcgtcgc ctcctccagc gcgtccgcgg cggcctcgac cgcgtcgggg
    20041 tcgccgtaca tccccgaata ctcgacgtag acgatttcct ggccgtacat ctgctcggcg
    20101 acctcggcgt aggccgccac gtcctcgggc gactggtcgc agtcggcgct ggtgagttcg
    20161 gccacgctgg cgtcggggtt catgatgatg taggcctcgg tggtggtccg gtcccagttc
    20221 acgtcgctcg atttgaccca ctccttgtgg aatccggtgg cccacgcgat gtccccggcg
    20281 ttgaggacga ccggcacgag gtagccgtcg aggtcgtcgt cgtccaccac gaccgcgggg
    20341 ttgctcggtt cctgatacag cggcacgtcg tacttcgcgc aggcgtcgat gacccgctgc
    20401 atcttctctt gggtcatgtc gagcgtcccg ccgatttcga gcgcgtcggt gccggtctcg
    20461 caaacgtcct cgaaggtctc gccctccgcg agcgtcttgt ccgggtccaa cttgacgatg
    20521 tggtcccagt cggtccaggg tgaggtagtc attatgcgtg taaacccgag gatgcggttt
    20581 aacatcttcg aatccacctt ttattacggc tgcgagtgcc agcggcgctc attctccgat
    20641 gaactgggcc gaaagccacg gccatggaaa caaatacggt tctgtatgca caatgtatac
    20701 gcatgagtac cagtatccgg gtctccaacg agacgaagga caaactctcc cggttgaaac
    20761 gggacgatga gacgtgggac gagttcctga accgactgac gaacgaggag gagcctatca
    20821 atatcggcgc gtggtcggac gacgtggctg accgtgcccg tgaagccgtc gaaagttccc
    20881 gagagagttt cgagcgatga cctttctcga ttcgtcggtt atcatcgaca tgctcagcgg
    20941 ggttgattcg actgtcgagt tcgttcagga gcagggggaa ccctacttca cctcctctct
    21001 ctgcgtcttc gaaatcctgg acggggtact cgggagtggt tcgaccgacg tcgttgcggc
    21061 ccgccaagac ttcgatgggg tccacgctct cgacctcacc gacgacatcg ctctggaggc
    21121 cgcacgtctt caggaccaac tcctcgacga cggccagcga atgcccaccc gcgacctact
    21181 catcgccgcg accgctcgtt cgacaggcga ccatctcgtc gtcgctgaca gcgatttcga
    21241 aacggccatc cttcagtctc acattcaagt gactaacctt tcgaagtgat ggtgttttca
    21301 gtcgggggag ggtagtctgc tggactatgg cagtccggag ctacatgtag aggccagcag
    21361 ttcacgaaca tatttgtaat cccgttttgt tggggctaat atgagtgaaa aggagtttat
    21421 tgagttcatc cccggtatta tatcttctac aaccgaagac cgtcatggtc acgaaatctc
    21481 gaaatcaact ttggagaaat gggcgaagga acttcgggac gaaaaaaaga ctattccatt
    21541 cactttcaat cattcctctg aaccagtagg tgaatggtta gatgctcagg tattaagtca
    21601 tggagattct gcttttcttg ctggcatggt aggtatttat tcgggtaatc aagatgcagt
    21661 agagagacta aatgatggag agtttggtgg cttaagtatt cagggtacta catatcggaa
    21721 tatcacagag aaccagttta cttcagcaga tgaagtaata tcgctatcag tagaaccttc
    21781 atggtcagaa tctattggcg gtataatcga ccaacagggg gcaggttatc gctttgaaat
    21841 tcagaagtca gaagtcggtc ttgcgttatt tgagattgta attgggaata ttgatggcat
    21901 tattcaggca ctcattatga ttcatgccta ctgtacgtat cagagaaaag tttttgagga
    21961 ggagaatcaa accgaggagt catctactcg ggcaaatatt caacttcctg atggcacaga
    22021 agttaacctt gtagagaata acgcaaagga ggtcatagtg cagttagaag agtcgggtta
    22081 tgaagtccaa attaatcctg aagaagcaga acagctctcc gacacgtatc aaaaggccat
    22141 caaagaaaaa gacgctgaag acgattaaac ttcacatcct ccaaacccaa agccggtaga
    22201 tattctctcg atacaactcc tcgatgtcct cgatgcccgc gtccgagagc ttctcggctg
    22261 tcttcgcgcc gatgccgtcg agcgattcgg ggtcgcttcc cgagtcgctc tcgcgggcct
    22321 tatgcggcaa tacgccgcaa ttcaccgcga gtgaacgata ctgtcggctc acttctcttc
    22381 atcgtctgtc cgagcgagac cttcccagat ggccatgaaa ctagacagaa tcactactgt
    22441 ttgtttaatc ggccgaatgt ctatcccggc aagtaacaga cagagacaga cgaccgtaac
    22501 cgctaccaaa cctatcaggc gtcgctgatt tcgtttgcag agacggctcc agaggtgaat
    22561 tgcaagcgcg attgcgaggc gatacagggc gtaggccggt ccgggtgtat acatttctcg
    22621 tgggggtcag ttggacccac ttcgcgaggt ccagacgtag ctgtcgaatc attgcgatga
    22681 agcaagtgga ttcagacagc ataccgggac ccaaagggtg agagggcacg ggggaagcct
    22741 tgactcgttt gctcgtgtta cggagcccct cgtccgggtg gactggccat cgcctctcgt
    22801 ccgcaggatg ctgacctact cacgcgggaa cgccagaacg gggtttcata cgaattacac
    22861 tgtcgcactc atacataaaa ccttcccaga aatcgacacg aatcaggcga aggctatcag
    22921 tcggctttcg ccttccagcc ccgaagccta tcctcgctca cgccctgcac ctgagaggcc
    22981 accgtctcga cttcggcctc cttcaggtcc tcgatgctct cgataccggc ctcagagagc
    23041 ttctcggcgg tcttcgagcc gatgccgtcg agcgtttcga ggtcgcttcc ggactcgctc
    23101 tcgcgggcct tgaactcccg gtagttgcag atgggacagc ccagttccca cgggtcgtcg
    23161 ccgctgtgga tgacgagttc ggg
//
