LOCUS       NZ_SBIT01000001        20324 bp    DNA     linear   CON 23-OCT-2024
DEFINITION  Halorussus ruber strain YC25 Scaffold1_1, whole genome shotgun
            sequence.
ACCESSION   NZ_SBIT01000001
VERSION     NZ_SBIT01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Halorussus ruber
  ORGANISM  Halorussus ruber
            Archaea; Methanobacteriati; Methanobacteriota; Stenosarchaea group;
            Halobacteria; Halobacteriales; Haladaptataceae; Halorussus.
REFERENCE   1  (bases 1 to 510403)
  AUTHORS   Cui,H.-L.
  TITLE     Genome sequence of Halorussus ruber YC25, isolated from an inland
            salt lake of China
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 510403)
  AUTHORS   Cui,H.-L.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-JAN-2019) School of Food & Biological Engineering,
            Jiangsu University, 301 Xuefu Road, Jingkou District, Zhenjiang,
            Jiangsu 212013, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. Dec-2018
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004765785.1-RS_2024_10_23
            Annotation Date                   :: 10/23/2024 04:20:59
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,396
            CDSs (total)                      :: 4,336
            Genes (coding)                    :: 4,270
            CDSs (with protein)               :: 4,270
            Genes (RNA)                       :: 60
            rRNAs                             :: 3, 3, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1 (5S, 23S)
            partial rRNAs                     :: 3 (16S)
            tRNAs                             :: 51
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 66
            CDSs (without protein)            :: 66
            Pseudo Genes (ambiguous residues) :: 0 of 66
            Pseudo Genes (frameshifted)       :: 18 of 66
            Pseudo Genes (incomplete)         :: 50 of 66
            Pseudo Genes (internal stop)      :: 6 of 66
            Pseudo Genes (multiple problems)  :: 7 of 66
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:04:38
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 70021
            Orig. end                         :: 90345
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            SBIT01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20324
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20324
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20324
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10324](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10324
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(845..1522)
                     /gene="phoU"
                     /locus_tag="EPL01_RS04900"
     CDS             complement(845..1522)
                     /GO_process="GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA]"
                     /GO_process="GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene="phoU"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006651737.1"
                     /locus_tag="EPL01_RS04900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="WP_135824147.1"
                     /transl_table=11
                     /translation="MPREDYQQKLTDLRENVLYMSEVVMERLRMGLDALEQKDDDLAWE
                     VIDGDEEVNQLYLELEQDCIDLLALQQPVAGDLRFIAASFKIITDLERIGDLATNLGEY
                     THEANHDVFPEVDIQELGALTLDMIDDAMTAYADEDTDGCYSIAERDDDLDELCERASE
                     IVVRDLIETELENNTEEEVEQLLQDVSRLLLTVRDLERVGDHAVNIAARTLYMVENDDE
                     LIY"
     gene            complement(1587..2267)
                     /gene="phoU"
                     /locus_tag="EPL01_RS04905"
     CDS             complement(1587..2267)
                     /GO_process="GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA]"
                     /GO_process="GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene="phoU"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004518125.1"
                     /locus_tag="EPL01_RS04905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="WP_135824148.1"
                     /transl_table=11
                     /translation="MPRTGFQNRLESLREAVLGMGDLVVSRLRKGLVALDRQNHELAWD
                     VIDGDEEVNRRYLELEQDCIDLLALQQPVAGDLRFVAASFKIITDLERVGDLAVNLAEY
                     ALYADQKVFEGVNLRDVGERAVEMVEAALTAYADEDAVACVALADRDADLDATCERASE
                     LVVRDLIETELGDDADNEEVELLLQDVSRVLLTIRDLERVGDHAVNVAARTLYMVETDD
                     RLIE"
     gene            complement(2561..3418)
                     /gene="pstB"
                     /locus_tag="EPL01_RS04910"
     CDS             complement(2561..3418)
                     /EC_number="7.3.2.1"
                     /GO_component="GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA]"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA]"
                     /GO_process="GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pstB"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010612722.1"
                     /locus_tag="EPL01_RS04910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="WP_394346242.1"
                     /transl_table=11
                     /translation="MTVSGESQEQLKDEWTDYQFDGAPKISVEDLDVFYGDDHAIQSVS
                     MDIPKNSVTALIGPSGCGKSTFLRCLNRMNDRINSARVDGSVEIDGEEIYQDGVNLVEL
                     RKRVGMVFQAPNPFPKSIRDNIAYGPRKHGDINDGLLDKLLGRAEPEKEDEIVERSLKQ
                     AAIWDEVKDRLDDNALGLSGGQQQRLCIGRCLAVDPEVILMDEPASALDPIATAKIEDL
                     IEELSEDYTVVVVTHNMQQAARISDQTAVFLTGGDLVEYGETDQIFENPNSQRVEDYIT
                     GKFG"
     gene            complement(3490..5112)
                     /gene="pstA"
                     /locus_tag="EPL01_RS04915"
     CDS             complement(3490..5112)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA]"
                     /GO_process="GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pstA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008384636.1"
                     /locus_tag="EPL01_RS04915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="WP_135824150.1"
                     /transl_table=11
                     /translation="MSYETNDLVTEESSLSERVAAAVVGLNVLSVVMGFAAVFQWTEVE
                     SEFFGVSLFNLYGLALVATGLAVIALGVVSRAGLVDTTPDRSAGLLTGGLFGLIGVVTG
                     GLFASQTLGFGVFGWLPIALLFGVGFGVVTVLPREDIGSTLPAGALSIVVGALFLLNVV
                     TTEWEWEPEGFSAAFTGPVVGPVLTIFAGLVCAWAAAKAHEGFGTRGRQAGAYLLVGLN
                     AFGMLGVLLLLILFVAGKGWSRMVEGVKFGLFSEPAFWFQMPGLDQYVVFEIPGVWFYW
                     PFTMNGYSLSKDVMNGVLPSIVGTVWLVIGAVLFAVPLGVGAAVFLTEYAEQGGFTRAV
                     EIATNGLWSTPSIVYGLFGYAFLVPRLGNTTSLLAGQLVLGFMLLPLVLITSREAIKTV
                     PKEYRDASAALGVSQWETIKSVVLPAAMPGVITGVILGVGRIAGETAPILLVATGNLQA
                     SRGPQVLTNFHFTSSPPFVANPALLDSISALPYKLYATITAGVVSSDPAFGWATALVLL
                     IVVLSFYAVGIVSRIYFRRKLEQ"
     gene            complement(5109..6182)
                     /gene="pstC"
                     /locus_tag="EPL01_RS04920"
     CDS             complement(5109..6182)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA]"
                     /GO_process="GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pstC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007540729.1"
                     /locus_tag="EPL01_RS04920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="WP_135824151.1"
                     /transl_table=11
                     /translation="MIGSIDTRVRSARTTVEDMDRGAQFVDGVAVASVLAALAAFLVAP
                     AYTVFPLLAFFGVTAYGWKSHQANTAKLLMFLMTASTIVILGLITVYLVLRSLPIFQAM
                     GLDLLLKTNKPLWSTSEGVYSLVPMMWGTLVTTILAMAIAAPLGVAGALFISEIAPSWA
                     REVIKPGIEILAGVPSIVYGFIGYTIINTYMMEEFKLANFGSLFAAALVIGVMSLPTVV
                     SVAEDAIDSVPESMKSGSLAMGATDWQTIKSVTIPASFSGVSAAVLLGVGRAVGETMAV
                     TVMLPHQQVLPDPIYDVFAGTETLTSLIAGQYGIASGDQMSALFAAGVVLFVTVLGLSI
                     GSQLIEAHMERKLGGSQ"
     gene            complement(6179..7270)
                     /locus_tag="EPL01_RS04925"
     CDS             complement(6179..7270)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006053629.1"
                     /locus_tag="EPL01_RS04925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PstS family phosphate ABC transporter
                     substrate-binding protein"
                     /protein_id="WP_135824152.1"
                     /transl_table=11
                     /translation="MRERPSVDRRTILLGGGTAIASLAGCVSTSKTPPGSRGEATTTEE
                     SNNSSSDQLKAGGSSTVYPITSKAASVWNSNPPADDEEYWGPSNYGIDTDERLANYWAN
                     KYEKFEADGSNPPFKVTVGLSHSGTGLEKLKNGLVDIGNASASVSAEFPDASEEELDKF
                     TNHVVGVDAQPIVVSKEIYEAGVKKLTAEQVRKIYQGEIENWSEIDAYDGEDKDIQAIG
                     RAEGSGTDTAFRSNMLGGPDASMGGVDVRKGQNQQVKTIVANSNNAIAYMALAFLTSET
                     PTVKLSFDGKVYERGKNLSEKGYPLSRDLHCYTYDGTSEMEAAYLRMLISEFGQKKFVE
                     TSGYSMLTEKRRKNQLDKLPDAK"
     gene            7539..8540
                     /locus_tag="EPL01_RS04930"
     CDS             7539..8540
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007141674.1"
                     /locus_tag="EPL01_RS04930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphate uptake regulator PhoU"
                     /protein_id="WP_135824153.1"
                     /transl_table=11
                     /translation="METRKVQVTGGSTFTVSIPKDWATENGIEAGNRVEFHPEGDSLLL
                     SPRTTEDTVEGTVDITDLEGAELKRTVFTLYVSGFDIINLESTRVTPDQRRTVRDATQG
                     LVGLEVIEETSDRVVLQDLLDSSELSIHNAITRMRLVSATMLQDAVTALVENDDSLAKD
                     VIERDDDVDRLWFMVSRVFRSALRNPSTAADIGLPRETCFDYHSSARQLERIADHAAKI
                     GQLSLNLEEVPDEVAEALEDLHAEAADIVEMAMDALLEEDGNEATRLGNEARERVRGID
                     QHTRAVDDLIREMDAQRAQQLSLVVDSLSRSADYGGNIAETALQKAAPRPEN"
     gene            complement(8754..9896)
                     /locus_tag="EPL01_RS04935"
     CDS             complement(8754..9896)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005538172.1"
                     /locus_tag="EPL01_RS04935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CBS domain-containing protein"
                     /protein_id="WP_135824154.1"
                     /transl_table=11
                     /translation="MNIADIVTADYTELEAESNVGKARSVFEEENPKGIIVTRAGDYEG
                     VITQKQLLRSHIEDHTKVETLTKPAPKVERTDDVRDVARTLVEGGTKVAPVFESGNLWG
                     VISQDLILEAVLENLDSLTVEQIYTENVVTIAEDATLGQAINQLREHGVSRLPVVDEDG
                     FLTGVVTTHDVVDFATRNVEKTTVGDRSGEGERLLDLPVYDVMSSPAATTNLSESVKDA
                     VERMLENDYSGLVVTPEDDDRVVGGVVTKTDVLRALSYTEEDVMDVQVTNVNLLDTLSR
                     ESIRESITEISDKYQDMRVRHAHVRFHEHKEKLRGTPLIQCKIRLRTNRGQAAGSGEGY
                     GAEQAFGVARDKLERNVLEMKGVESDREYEGQLLRKLGEL"
     gene            10001..10324
                     /locus_tag="EPL01_RS04940"
     CDS             10001..10324
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl_fung"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004591602.1"
                     /locus_tag="EPL01_RS04940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lycopene cyclase domain-containing protein"
                     /protein_id="WP_135824155.1"
                     /sec_met_domain="Lycopene_cycl_fung (E-value: 6.7e-14,
                     bitscore: 47.2, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVPDIGAVFGEYTYLATEVVWGAVAIGLLYRADALVQAGRTIAVL
                     YPIAYVWDWYTLHIGVFSIPLRTGIELLGIPIEEHIFMVVVPALVLGIHTNLENWGREN
                     RSD"
     gene            10497..11165
                     /locus_tag="EPL01_RS04945"
     CDS             10497..11165
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007983696.1"
                     /locus_tag="EPL01_RS04945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_210424076.1"
                     /transl_table=11
                     /translation="MSTIGDSSGTGSTEPEETPDQQDTAVAAEEVSDIVESEDEEEVQQ
                     KLSRDLVFDVLKNRRRRYALHYLRRADDTVQLSELAEQVAAWENDIEVEAISAAERKRV
                     YTALYQSHLPKLDDAGIVEYNQNRGIVKLSGAAEQLDVYLDLEAQPDIPWCNWYLGLAV
                     AGLGLLTGAWLGLPPFSLVADVLLATVIVAAYGAVALAHTYYAQHADAAGETPPEIQES
                     "
     gene            11168..11734
                     /locus_tag="EPL01_RS04950"
     CDS             11168..11734
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EPL01_RS04950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_135824156.1"
                     /transl_table=11
                     /translation="MREAVRSGVTSLGDVEPTDDAFAPAGTQTLVRTPAEADPLSALPA
                     RTFDNLLVVSARDHPNKLEARVERAGHDPANVGVVPVSPAARDYDGDLWTTDPVNPDDL
                     TGLGMRFSDAIRHVESGSGWVVIDALGVLLMYADDARVCRFFQTLSNRVRAKEVHGVYF
                     TNHDAVADETYEQLRAMCDAEYRIE"
     gene            11910..12806
                     /locus_tag="EPL01_RS04955"
     CDS             11910..12806
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EPL01_RS04955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="ubiquinol-cytochrome c reductase iron-sulfur
                     subunit"
                     /protein_id="WP_368279087.1"
                     /transl_table=11
                     /translation="MDADKYPPEDDRRRFVKGVVGTAATTVLNASTSAAGGTGGPTTYV
                     GIENTDGPAPRGMPIVPLTIDDEGYLKGVWPEVREKELKDGSTLTYTAQEMGGVTYTGR
                     WFQYCGVQIAQGLRPETDQDNFLRSKPGLYEWQADHEQGRKLHVDDFADYEEWTNGIGS
                     AGAGKPAQTTWRSQSEGDEEVKKLPVQVLRSPKVSDLPAESDHGAFLRAATESDFVAWL
                     DKCTHFCCTPGFNSSRDASKFDATDAGTASVTSRCTTRFRRSKSRSTPSHDQSSVVAGR
                     FFEVEIGVAQTARLTTG"
     tRNA            complement(12947..13020)
                     /anticodon=(pos:complement(83005..83007),aa:Val,seq:gac)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="EPL01_RS04960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /product="tRNA-Val"
     gene            complement(12947..13020)
                     /locus_tag="EPL01_RS04960"
     gene            13642..14646
                     /gene="trpD"
                     /locus_tag="EPL01_RS04965"
     CDS             13642..14646
                     /EC_number="2.4.2.18"
                     /GO_function="GO:0004048 - anthranilate
                     phosphoribosyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="trpD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007143840.1"
                     /locus_tag="EPL01_RS04965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="WP_135824157.1"
                     /transl_table=11
                     /translation="MQDYIERVTDGEDLTLDQAREAATAVFEGATEAQIGALLSALRAK
                     GETETEIAGFAQGMRDAARTIDPDRAPLVDTCGTGGDDYDTINVSTTSAIVASGAGVPV
                     AKHGNYSVSSSSGSADVLEEVGVEVEAEPPAVEAAIEDDGIGFMLAPVFHPAMKAVIGP
                     RKELGMRTVFNVLGPLTNPAGADAQIVGVYDPDLVPVLARSLSKMSVERALVVHGSGMD
                     EIAVHGETTAAEVRGDEIEEYTITPEDVGLSRHPVADVSGGTPEENAEDMRGIVEGDVT
                     GAKRDIILANAGAALYVAGEADSLEDGAQLAEKAIEDGAAADHLERLRTTVPA"
     gene            14643..15326
                     /locus_tag="EPL01_RS04970"
     CDS             14643..15326
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006186225.1"
                     /locus_tag="EPL01_RS04970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="WP_135824158.1"
                     /transl_table=11
                     /translation="MTRVKICGLTAREDLRVAVEAGADAVGLLVDVPVDSPREIDTQRA
                     VELAEAAPPFVTTVLVTMPDSPERAVELTSAVDPDAVQVHGNLGVGDIAYLTANVNAQV
                     LKVVDAAEPEDARRYDDVADALLVDSVDEEGAGGTGRTHDWERTTEFAADLDSPVVLAG
                     GLTPDNVADAVRSVEPFAVDVASGVERSGTDASETAPSTTGRKDPDAVADFVANAKRAY
                     STPTP"
     gene            15323..16948
                     /gene="trpE"
                     /locus_tag="EPL01_RS04975"
     CDS             15323..16948
                     /EC_number="4.1.3.27"
                     /GO_function="GO:0004049 - anthranilate synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="trpE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1018: isochorismate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006067689.1"
                     /locus_tag="EPL01_RS04975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="anthranilate synthase component I"
                     /protein_id="WP_135824159.1"
                     /transl_table=11
                     /translation="MKPGRKQFADLAGGDDLSVVRIEAELDVETTPLSAYAALTGRSTD
                     ADAAEYAFLLESAEKTASSDPDGAFSAEQSGDRHARYSYVGYDPDAVVTVAPDETNVES
                     LGGRAAKFVAGDHSGDALDALRSAMPDAERRGFPEGDRQHFEGGLVGFLAYDAVYDFWL
                     DERGVERPESRFPDAQFVLNTKTVAFDHRAGTASLVFTPLVGPDDDPAEIYDDLRAEAE
                     RVADLLESASSPETGGFVCESETAGPREEYEEAVRTAKEHVLDGDIYQGVVSRKRELRG
                     DVDPLGFYDALREVNPSPYMYLLGYDDRTVVGASPETLVSVRGREVMANPIAGTCSRGS
                     SPVEDRRLAGEMLADEKEQAEHTMLVDLARNDVRRVSEPGSVQVEEFMNVLKYSHVQHI
                     ESTVTGRLAAGSDAFDATRASFPAGTLSGAPKIRAMELLDDLERSARGLYGGGVGYYSW
                     SGDADFAIVIRTATIESDADASPPDRITVQAGAGIVADSDPSAEYEETEKKMDGVLTAL
                     DRIEESRKRRPTDPDETEAPGVSR"
     gene            16945..17574
                     /gene="trpG"
                     /locus_tag="EPL01_RS04980"
     CDS             16945..17574
                     /EC_number="4.1.3.27"
                     /GO_function="GO:0004049 - anthranilate synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="trpG"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1249: carbamoyl phosphate synthase small subunit"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006088184.1"
                     /locus_tag="EPL01_RS04980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="anthranilate synthase component II"
                     /protein_id="WP_135824160.1"
                     /transl_table=11
                     /translation="MTASVEGDRRQSPAAEDLQVLFVDNFDSFTYNLVEYTSEHAETEV
                     VRNTASLADVREADPDAIVVSPGPGHPANERDVGVTLDVFREVSPEVPTLGVCLGLEAA
                     VYAYGGSVGRAPEPVHGKAFPVDHDGRGVYAGLEQGFRAGRYHSLVATEVPDCFEVTAT
                     TDHEGEELVMGVRHREHPIECVQFHPESVLTAVGHDVIRNFVREVA"
     gene            complement(17830..18009)
                     /locus_tag="EPL01_RS04985"
     CDS             complement(17830..18009)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008007765.1"
                     /locus_tag="EPL01_RS04985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_246045630.1"
                     /transl_table=11
                     /translation="MNIALAAGLLASPLGELLVGLVALAAIVLIGRIVLSVAWKLLLVA
                     IVVVGALYTAGVLL"
ORIGIN
        1 ctgccttcgg tgaactcggc cagcgcgtct cggagcgcgg tcgccccgtc tggactgtag
       61 tagtggtgtg ccccctcgac gaggcccggt actgtctcgg gtgcgagttc cgcgccggtc
      121 gtcacgacga ggtagtcgta gtcgagcgtc gcgccgtcgt cgcgctcgat tcgcttcgcg
      181 tctgtgtcga tttgctggac gtgcgcgatg cggagcctga cccgacggtc cagcagttgg
      241 tcgagcggtc gcacgccgtc cgctacgtct cgcatcccga acgcgacgta gaggaacacg
      301 ggcttgtaga cgtgttccgg actgtccgta accagcgaca cctcgacctc gcccgcgtct
      361 atctcctcgg ccagttcgtc ggcgagtcga ttggcgagga cggtcccgcc gaccccgccg
      421 ccgacgattg cgattcgccg cgtcatcgtt ctcccgttct cgagcgtagt tgcgtcatct
      481 cgtacccccg catccgcgta cggcgtcgat ggggttaatc gtgtgccccg ctggagaccg
      541 tttccgtcga ttcgagtgcg accgcttgaa tcgacggacg ggttaggacg gccgtctcgg
      601 tacggctaca ggcgtgttta gatgcctaag acaaataata ttatgtcttt tacacaattt
      661 tatattttct tactgctcgt ataggtctct ttctgtcggg ccgacgctcg aggagaccag
      721 cggtcggcgt gggcgttcgt ttcgaccgac tgctcggaag acgcaaggtg ccttccggtg
      781 ggttctgcca gcgaaagagt gcaagcccgc tgcttgcgcg accgagtgca gcaaaaagtg
      841 gtagctaata aatgagttcg tcgtcgttct cgaccatgta gagggtccgg gcggcgatgt
      901 tgaccgcgtg gtcgccgacg cgctccaagt cccgaactgt caggaggagc cgcgagacgt
      961 cctgcagcag ttgctcgact tcctcctcgg tgttgttctc cagttcggtc tcgatgaggt
     1021 cccgcaccac gatttcgctg gcgcgttcgc agagttcgtc caagtcgtcg tcgcgctcgg
     1081 cgatgctgta acagccgtcg gtgtcctcgt cggcgtaggc cgtcattgcg tcgtctatca
     1141 tgtcgagggt gagcgcgccg agttcctgga tgtccacctc ggggaacacg tcgtggttgg
     1201 cctcgtgggt gtactcgccg aggttggtgg cgaggtcgcc gatgcgttcg aggtcggtga
     1261 taatcttgaa cgacgccgcg atgaatcgca ggtcgcccgc gaccggctgt tggagggcca
     1321 gcaggtcgat gcagtcctgt tcgagttcga ggtagagttg attgacctcc tcgtcgccgt
     1381 cgatgacctc ccacgccaag tcgtcgtcct tctgttcgag ggcgtcgagt cccatccgaa
     1441 ggcgctccat cacgacctcg ctcatgtaga ggacgttctc gcggaggtcg gtgagcttct
     1501 gctgatagtc ctctcggggc atacctacga atgggtgtgt ccccctgttg tacctttcgc
     1561 ccgcgctagc tgacgggcgt cggacactac tcgatgagtc ggtcgtcggt ctcgaccatg
     1621 tagagggtcc gggccgcgac gttgaccgcg tggtcgccga cgcgctccaa gtcacgaatc
     1681 gtcagcagga cccgcgagac gtcctgtaga agcaactcga cctcctcgtt gtctgcatcg
     1741 tcgccgagtt cggtctcgat gaggtcccgg acgacgagtt cgctggcgcg ctcgcaggtc
     1801 gcgtcgaggt cggcgtctcg gtcggccagc gcgacacagg ccacggcgtc ctcgtcggcg
     1861 taggcggtca gcgccgcctc gaccatctcg actgcgcgct cgccgacgtc ccgaaggttc
     1921 accccttcga acaccttttg gtcggcgtag agggcgtact cggcgaggtt gaccgccaag
     1981 tcgccgaccc gttcgaggtc ggtgataatc ttgaacgacg ccgcgacgaa ccgcaggtcg
     2041 cccgcgaccg gctgttggag cgccagcagg tcgatgcagt cctgctctaa ctccagatac
     2101 cgccggttga cctcctcgtc gccgtcgatg acgtcccatg cgagttcgtg gttctgccgg
     2161 tcgagcgcga ccagtccctt ccggaggcgc gagacgacga ggtcgcccat cccgaggacg
     2221 gcctcgcgga gcgattcgag tcggttttgg aatccggttc gtggcatgag ggatgagttc
     2281 gtgtcggtgt ggttgagtgc gtgattggcg tgtcgatgcg tcgggcgacg aatttggcgc
     2341 gaccagtgat tcgctcggtc gagtttccaa cagttccgga atctcagcaa tccaccgcag
     2401 aacaacgaaa tctaccgcga gcgaacgaac gtgagcgagc ggcccaagga atccctcgaa
     2461 cgagcgccga aggcgctcgt gagggggtga cgccgtggtt ttcatgaaag ttttgccagc
     2521 gaggaagcgc ctacggcgct tccgagcgca gcaaaagttt ctatccgaac ttacccgtga
     2581 tgtagtcctc gacgcgctgg ctgttggggt tctcgaagat ttggtcggtc tcgccgtact
     2641 ccacgaggtc cccgccggtc aggaagaccg cggtctggtc ggagatgcgg gcggcctgct
     2701 gcatgttgtg ggtgacgacg accaccgtgt agtcctcgga aagttcctcg atgaggtcct
     2761 cgattttggc ggtggcgatg gggtcgagcg cggaggccgg ttcgtccatc aggatgacct
     2821 cggggtcgac cgcgaggcag cgaccgatgc agaggcgctg ttgttgcccg ccggagaggc
     2881 ccagggcgtt gtcgtcgagt cggtccttga cctcgtccca gatggcggcc tgcttgagcg
     2941 agcgctcgac gatttcgtcc tccttctcgg gttcggcgcg cccgaggagt ttgtcgagca
     3001 ggccgtcgtt gatgtcgccg tgcttgcgcg ggccgtaggc gatgttgtcc cgaatcgact
     3061 tcgggaaggg gttgggtgct tggaacacca tgccgacgcg cttgcggagt tccacgaggt
     3121 tgacgccgtc ctggtaaatc tcctcgccgt cgatttcgac cgagccgtcg acgcgcgcgg
     3181 agttgatgcg gtcgttcatc cggttgagac agcgcaggaa ggtggacttc ccacagcccg
     3241 agggaccgat gagtgcggtg acgctgttct tgggaatgtc catcgagacc gactggatgg
     3301 cgtggtcgtc gccgtagaac acgtcgaggt cctcgaccga aatcttgggt gcgccgtcga
     3361 actggtagtc ggtccactcg tctttgagtt gctcttggct ctccccgctg accgtcatcg
     3421 actggctcgc ggactgttcg tcggtcgcct gttcgctcgc ttgctcgctc tgtttgaatt
     3481 ctgcgttgct cattgttcga gtttcctccg gaagtagatt cgagagacga taccgaccgc
     3541 gtagaacgac agcaccacga tgagcagcac cagcgcggtg gcccatccga acgcggggtc
     3601 ggaactgacg acgcccgcgg tgatggtcgc gtagagcttg tagggaaggg cgctgatact
     3661 gtccagcagc gccgggttcg ccacgaacgg cggactcgac gtgaagtgga agttcgtcag
     3721 cacctgcggg ccgcgactgg cctgcaggtt accggtcgcc accagcagga tgggtgccgt
     3781 ctcgcccgcg atgcggccga cgccgaggat gacgcccgtg atgacgcccg gcatcgcggc
     3841 cgggaggacg acgctcttta tggtctccca ctggctgacg ccgagcgccg cgctggcgtc
     3901 ccggtactcc ttgggcaccg tcttgatggc ctcccgactg gtgatgagga ccagcggcag
     3961 gagcatgaag cccagaacca actggcccgc cagcagcgag gtcgtgttgc cgagtcgcgg
     4021 cacgaggaat gcgtagccga acaggccgta gacgatgctg ggcgtactcc acaggccgtt
     4081 ggtcgcaatc tcgaccgcgc gggtgaaccc gccctgttcg gcgtactcgg tgaggaacac
     4141 cgccgcgccg acgccgagcg ggaccgcgaa cagcaccgcg ccgatgacca gccagaccgt
     4201 cccgacgatg gagggcagga cgccgttcat cacgtctttc gacagcgagt agccgttcat
     4261 cgtgaacggc cagtagaacc agacgccggg aatctcgaag acgacgtact ggtcgaggcc
     4321 gggcatctgg aaccagaagg cgggttcgct gaacaggccg aacttgacgc cttcgaccat
     4381 ccgactccag ccctttccgg cgacgaacag gatgagcagg aggagaaccc ccagcatccc
     4441 gaaggcgttc aggccgacga gcaggtacgc cccggcctgt cgcccgcggg tgccgaagcc
     4501 ttcgtgggcc ttcgccgcgg cccacgcgca gacgagtcct gcgaagatgg tcagcaccgg
     4561 gccgacgacc ggaccggtga acgccgccga gaagccctcg ggttcccact cccactcggt
     4621 cgtgacgacg ttgagcagga acagcgcgcc gacgacaatc gacagcgcgc ccgcgggaag
     4681 cgtcgaaccg atgtcctcgc ggggcaggac cgtcacgacg ccgaagccga cgccgaacag
     4741 cagcgcaatc gggagccagc cgaagacgcc gaagccgagc gtctgggagg cgaacaggcc
     4801 gccggtcacg accccgatga ggccgaacag gccgccggtc aggagtccgg cgctccggtc
     4861 gggcgtcgtg tccacgaggc cagcccgcga gacgacgccg agcgcgatga ccgcgaggcc
     4921 ggtcgccacc agcgccaagc cgtagaggtt gaacaggctg acgccgaaga actcgctctc
     4981 gacttcggtc cactggaaga cggccgcgaa gcccatcacg accgagagga cgttcagacc
     5041 cacgacggcc gcggcgactc gctcggacag cgaggactcc tcggtcacga ggtcgttcgt
     5101 ctcgtagctc attggctacc acccagcttg cgctccatgt gcgcctcgat gagttgcgac
     5161 ccgatgctga gtccgaggac cgtcacgaac agcaccacgc ccgccgcgaa cagcgccgac
     5221 atctggtcgc cgctggcgat gccgtactgg cccgcgatga ggctggtgag cgtctcggtt
     5281 cccgcgaaca cgtcgtaaat cgggtcggga agtacttgct ggtggggcaa catcacggtc
     5341 acggccatcg tttctccgac tgctcgaccg acgcccagca ggaccgcggc cgagacgccc
     5401 gagaacgacg ccgggatggt gacgctcttg atggtctgcc agtcggtcgc gcccatcgcc
     5461 agcgacccgc tcttcatcga ctcgggcacg ctgtcgattg cgtcctcggc gaccgagacc
     5521 acggtcggca gggacatcac gccgatgacc agcgcggccg cgaacaggct cccgaagttg
     5581 gccagcttga actcctccat catgtacgtg ttgatgatag tgtagccgat gaacccgtag
     5641 acgatggacg ggacgccagc cagaatttcg atgccgggct tgatgacttc gcgcgcccaa
     5701 ctcggcgcga tttcgctgat gaacagcgcg ccagccacgc ccagcggcgc ggcgatggcc
     5761 atcgccagta tcgtcgtcac caacgtcccc cacatcatcg gaaccagcga gtagacgccc
     5821 tcgctggtgc tccagagcgg tttgttggtc ttgagtagca ggtcgagacc catcgcctgg
     5881 aatatcggaa gcgaccggag gacgagatac accgtgatga gtccgaggat gacgatggtc
     5941 gaggccgtca tcaggaacat taggagcttg gcggtgttcg cttggtgaga cttccagccg
     6001 taggcggtga ccccgaagaa ggcgagcagg gggaacaccg tgtaggctgg cgcgacgagg
     6061 aacgccgcca gcgcggcgag gaccgacgcg accgcgacgc cgtcgacgaa ctgcgccccg
     6121 cggtccatgt cctcgacggt cgttcgtgcg gaccgaacgc gggtatcgat gcttccgatc
     6181 atttggcgtc gggtagcttg tcgagttggt tctttcgccg tttctccgtc agcatcgagt
     6241 agcccgacgt ttcgacgaac ttcttctggc cgaactcgct gatgagcatc cggaggtagg
     6301 ccgcctccat ctcggaggtt ccgtcgtagg tgtagcagtg aaggtcacgc gagaggggat
     6361 atcccttctc cgagaggttc ttgccgcgct cgtacacctt cccgtcgaac gagagcttga
     6421 cggtcggcgt ctcggacgtg aggaacgcca gcgccatgta ggcgattgcg ttgttcgagt
     6481 ttgcgacgat ggtcttgacc tgctggttct ggcccttgcg cacgtccacg ccgcccatcg
     6541 aggcgtccgg gccaccgagc atgttcgacc ggaaggcggt gtcggtgccc gacccctcgg
     6601 cgcggccgat agcctgaatg tccttgtcct cgccgtcgta ggcgtcgatt tccgaccagt
     6661 tctctatctc gccctgatag attttccgga cctgctcggc ggtcagtttc ttcacgcccg
     6721 cctcgtagat ttccttgctg acgacgatgg gttgggcgtc cacgccgacg acgtggttcg
     6781 tgaacttgtc cagttcctcc tcgctggcgt cggggaactc ggccgagacg gacgcgctgg
     6841 cgttgccgat gtccacgagg ccgttcttga gcttctccag tccggtgccg gagtggctca
     6901 ggccgaccgt caccttgaac ggcgggttcg agccgtcggc ctcgaacttc tcgtacttgt
     6961 tcgcccagta attagccagt cgttcgtccg tgtcgatgcc gtagttgctc ggtccccagt
     7021 actcctcgtc gtcggccggt gggttggagt tccacaccga cgcggctttg ctcgttatcg
     7081 ggtacaccgt agaggagccc cccgccttca gctggtccga agacgagttg ttggactcct
     7141 ccgtcgtcgt cgcttcccca cgactgcccg gtggcgtctt gctcgtactg acgcacccgg
     7201 cgagcgacgc gatggcggtg ccccctccga ggagaattgt tcgacggtct acagagggtc
     7261 tttcccgcat tgggattgat ttgccgaaga cgaagtaaat accctactat tatttctata
     7321 tagacgtact tatccatctg tattcaagtt tccgcgggtc gaacgcgaat cgcaaaccgt
     7381 gtttaggtgc cacacggtgg cagatacgac ggtcagacga ggaggacgcc acgggacgtg
     7441 gcaagcgccc atcatcgatt cgctggcctg ttgcgaagct tagagattcg tatatagatt
     7501 ggaatagatt tattgtctcc caccgccgcg ttccctacat ggaaacgcgg aaggtccagg
     7561 ttaccggcgg ctccacgttc accgtctcga ttccgaagga ttgggcgacc gagaacggaa
     7621 tcgaagcggg caaccgcgtc gaatttcatc ccgagggcga ctcgcttttg ctctcgcccc
     7681 ggacgaccga ggacacggtc gaggggacgg tcgatatcac cgacctcgaa ggagcggaac
     7741 tcaagcgaac ggtgttcacc ctctacgtca gcgggttcga catcatcaac ctcgaatcga
     7801 cccgcgtgac ccccgaccag cgacggacgg tccgtgacgc cacgcaggga ctcgtcggac
     7861 tggaggtcat cgaggagacc agcgaccgag tggtcctgca ggacctgctg gactcctcgg
     7921 aactgtcgat tcacaacgcc atcactcgga tgcgactggt ctcggcgacg atgcttcagg
     7981 acgccgtgac tgcgctggtc gagaacgacg acagcctcgc caaggacgtc atcgagcgcg
     8041 acgacgacgt cgaccgcctc tggttcatgg tctcgcgcgt gttccggtcg gcgctgcgca
     8101 accccagcac cgcggccgac atcggcctgc cccgcgagac gtgtttcgac taccactcca
     8161 gcgcccgcca actggagcgc atcgcggacc acgccgccaa aatcggccaa ctcagcctca
     8221 acctcgagga ggtccccgac gaggtcgccg aggcgctcga agacctccac gccgaggccg
     8281 ccgacatcgt ggagatggcg atggacgccc tcctcgaaga agacggtaac gaggccactc
     8341 gcctcggcaa cgaggcccgc gagcgtgtcc gcggcatcga ccaacacacc cgcgccgtgg
     8401 acgacctcat ccgcgagatg gacgcccagc gcgcccagca actcagtctg gtcgttgact
     8461 cgctctcccg gagcgccgac tacggcggga acatcgcaga gaccgccctc cagaaggccg
     8521 cgccgcgccc cgagaactga gtgggtttcg ggagtctcgt ttcacagggc ctgccgcaag
     8581 acatatctat tcatttcttt actgcttcga tatatttgtt taacgaatag atagttgtct
     8641 ggtgtggacg cgcagcggcc caactcgtgg ggacgggcga tagcactcgc aggtacggaa
     8701 aatacagaaa aacgtccggg ggtcgtccgt ctcggcccgt cagcggctgc cgctcagagt
     8761 tcgcccagct ttcggaggag ttgcccctcg tactcgcggt cgctctcgac acccttcatc
     8821 tccagcacgt tgcgctctag tttgtcgcgc gcgacaccga acgcctgttc ggcaccgtag
     8881 ccctcgcccg acccagcggc ctgcccgcgg ttggtgcgga ggcgaatctt acactggatg
     8941 agcggcgtgc cccggagctt ctccttgtgt tcgtggaacc ggacgtgggc gtggcggacc
     9001 cgcatgtcct gatacttgtc cgaaatctcg gtgatggact cccgaatcga ctcccggctg
     9061 agggtgtcca gcaggttgac gttcgtgacc tgcacgtcca tcacgtcctc ctcggtgtac
     9121 gacagcgcgc gcagcacgtc ggtcttggtg acgacgccgc cgactactcg gtcgtcgtcc
     9181 tcgggggtga ccacgagacc cgagtagtcg ttctccaaca tgcgttcgac ggcgtccttg
     9241 acgctctcgc tcaggttggt cgtcgcggcg ggactcgaca tcacgtcgta gaccggcagg
     9301 tcgagcaggc gctcgccctc gcccgagcgg tcgccgaccg tggtcttctc gacgtttcgg
     9361 gtggcgaagt ccaccacgtc gtgggtcgtg acgacgccgg taaggaaacc atcctcgtcc
     9421 acgaccggga gccgcgagac gccgtgttcg cgcagttggt tgatggcctg cccgagcgtg
     9481 gcgtcctcgg cgatggtgac gacgttctcg gtgtaaatct gctcgaccgt cagcgagtcg
     9541 agattctcca gcacggcctc gaggatgagg tcctgactga tgacgcccca gaggttgccc
     9601 gactcgaaga cgggcgcgac cttggtgccg ccctcgacca gcgttcgggc cacgtcgcgg
     9661 acgtcgtcgg ttcgctcgac tttcggtgcg ggtttggtca gtgtctcgac tttggtgtgg
     9721 tcctcgatgt gcgagcgcag cagttgcttc tgagtgatga cgccttcgta gtctccggcg
     9781 cgcgtcacga tgatgccctt ggggttctcc tcttcgaaga cggaccgggc ctttccgacg
     9841 ttcgactcgg cctctagttc ggtgtagtcc gccgtaacaa tgtcagcgat gttcatcggt
     9901 acctgaagat actcctcgga tggccttgaa agttatcgcg cgtcgaagcg ggtgacaacc
     9961 ggcgatgggc tttatatact tgccgcgcca agggccggga gtggtacccg acatcggcgc
    10021 ggtgttcggc gagtacacgt atctcgctac ggaggtcgtc tggggggcgg ttgcgatagg
    10081 actcctttat cgagccgatg cgctggttca agccgggcgg accatcgcgg tactgtatcc
    10141 tatcgcctac gtctgggact ggtacacgct ccatatcggc gtgttcagca tccccctccg
    10201 gaccggtatc gagctcctcg gaatcccaat cgaggaacac atcttcatgg tggtagttcc
    10261 cgccctcgtg ctaggtattc acacgaatct cgagaactgg ggccgcgaga accgttcgga
    10321 ctgaaaccgc cgagagcggc cggtaagccc cggttaacgc gggacggcgg cgagatgaaa
    10381 cagacgtgca actgttcgta agcaacggtt tccggcgggt aaatggtgaa taacaaaggc
    10441 taatccgggc gatgtgttct atccatgctg ggttacgacc aaggggtggc atattaatga
    10501 gcaccattgg tgactcatcc ggaaccggaa gtaccgaacc ggaggagact ccggaccagc
    10561 aggacacggc tgtagcggcc gaggaagtct ctgacatcgt cgagtccgaa gacgaggagg
    10621 aagtgcaaca gaaactctct agagacctcg tcttcgacgt tctcaagaat cgccggcgac
    10681 gatacgccct ccattacctc cgacgcgcgg acgatacggt gcagttgtcc gaactcgcag
    10741 agcaagtggc ggcgtgggag aacgacatcg aggtggaggc aatttccgcg gccgagcgta
    10801 aacgagtcta caccgcgctc taccagtcac acctgccgaa actagacgac gcgggcatcg
    10861 tggagtacaa ccagaatcgc ggcatcgtga aactctcggg ggcggccgaa caactcgacg
    10921 tgtatctcga tctcgaagcc caacccgaca tcccgtggtg caactggtac ctcggactcg
    10981 cggtggcggg cctcggcctg ctgacggggg cgtggctcgg actgccgccg ttctcgctgg
    11041 tcgcggacgt gcttctcgcg accgtcatcg tcgccgccta cggagcagtc gccctcgcac
    11101 acacctacta cgcccaacac gcagacgccg cgggtgaaac accgccggaa attcaggagt
    11161 cgtagccatg cgagaagcgg tgcggtctgg agtgacctcc ctcggggacg tggaaccgac
    11221 ggacgacgca ttcgctcccg cggggaccca gacgctggtc cggacgccag ccgaggccga
    11281 cccgctttcc gccctccccg cgcgcacgtt cgacaacctc ctcgtggtct cggcgcgcga
    11341 ccacccgaac aaactcgaag cgcgcgtaga gcgggccgga cacgaccccg ccaacgtggg
    11401 tgtcgtaccg gtctcccctg cggcccgcga ctacgacggc gacctctgga cgaccgaccc
    11461 cgtcaacccc gacgacttga cgggcctcgg catgcggttc tcggacgcga ttcgacacgt
    11521 cgaatccggg tccggttggg tcgtcatcga cgcgctcggc gtcctgctga tgtacgccga
    11581 cgacgctcgc gtgtgccggt ttttccagac gctctcgaac agggtgcggg cgaaggaggt
    11641 ccacggagtc tacttcacca accacgacgc ggtggccgac gagacctacg aacaactccg
    11701 ggcgatgtgc gacgcggagt accgaatcga gtagttttcg gtcccctact cggtttcagg
    11761 gaccgcctga aacgcgctca gcgaccgttc tcgactacca acgggcggac agtagaacgc
    11821 gtcagggtat aactcctctg acgattccaa gctgttggac attatctact tctgctacga
    11881 ctcgaggaga cgtacttccg accggtccca tggacgcaga caagtacccg cccgaggacg
    11941 accgacggcg gttcgtgaaa ggcgtcgtcg gcaccgccgc gacgaccgtc ctgaacgcat
    12001 cgacctccgc cgccggtggc accggcggtc cgaccacgta cgtcggcatc gagaacaccg
    12061 acggtcccgc gccgcgcggg atgcccatcg tcccgcttac catcgacgac gagggctacc
    12121 tgaagggcgt ctggcccgag gtcagggaga aggaactgaa agacggcagt acgctcacct
    12181 acaccgccca agagatgggc ggagtcacct acaccggccg gtggttccag tactgcggcg
    12241 tccaaatcgc gcaagggttg cgccccgaaa ctgaccagga caacttcctg cggtccaagc
    12301 ccggcctcta cgagtggcag gccgaccacg agcagggccg gaagctccac gtggacgact
    12361 tcgccgacta cgaggagtgg accaacggta tcgggtcggc tggcgcgggc aaacccgctc
    12421 agacgacgtg gcgctcccaa tccgagggcg acgaggaggt caagaagctc ccggtgcagg
    12481 tgcttcgctc gccgaaagtg tcggacctgc ccgccgagag cgaccacggc gcgtttctgc
    12541 gcgcggccac cgagtcggac ttcgtcgcgt ggctcgacaa atgcacccac ttctgttgca
    12601 cgccggggtt caactcctcg cgggacgcct cgaagttcga cgcgaccgac gcgggtactg
    12661 ctagtgtcac cagtcggtgt acgacccgtt ttcgccggtc gaaaagtcgt tcaacgcctt
    12721 cccacgacca gagtagcgtc gtggctgggc gctttttcga ggtcgagatt ggagtcgcgc
    12781 agactgcacg actgactacg ggctagcaac acgactgcga gcgaagcgac tacctgctcg
    12841 gaagacgcgg gttgtcttcc ggcgtttttt atcgacgttt tacaagtgaa caactcccaa
    12901 gccaacggct tcggagttct gaaacgcggt aaaaggttga aggtagtggg tttgggcaga
    12961 tttgaactgc cgacctcctc catgtcaagg aggtgtcata accaactaga ccacaaaccc
    13021 aagttggtgc gacctccttc ggacgcattt cttcgtttgc cccggggata attgaacctt
    13081 tcggattccg acgcagtccg gcgatttaca atgaaggttc ggcctaacgg cgcggcgttc
    13141 ggccggtaga acggctagtt tcggcgagag aagggctttg gattcaactc gtcagctatg
    13201 atagtactca gggccggaga aataaatacc cttatttaag aaatatactt atggcttaga
    13261 gaagcaatta catttattta gttgttcgga agagattcag tctggaagcg ggagatagcc
    13321 tcagactcga gccaagccgt ctcccgcacc gcgaccgcac ctcgtcctcc ccaaactcct
    13381 gtgcttctcc ctcgtcgctt cgctcctcgg tgcgatgctc gtctactggc agacaacccg
    13441 cgtctgccga gccttcggct tcgccgaaga cctcgcgcgc gacgatggcg cggcgaacga
    13501 gccgccgcgc cagcgcgcgc cgggccgaac agttcaccga gcgccagccc ctcaacaaca
    13561 tccgaccggg agtcccgaca gctttaagtc gatgtacgat tgtgttcatt ataagactaa
    13621 gacgtacatt ggtgatttag aatgcaagat tacatcgaac gcgtcaccga cggggaggac
    13681 ctcacgctcg accaagcgcg agaggcggcg acggccgtct tcgagggtgc aaccgaggcc
    13741 caaatcggcg cgctcctctc ggcgctccgg gcgaagggcg aaaccgagac cgaaatcgcc
    13801 gggttcgcac aggggatgcg cgacgccgcg cggaccatcg accccgacag agcgccgctg
    13861 gtagacacct gcgggaccgg cggcgacgac tacgacacga ttaacgtctc gaccaccagc
    13921 gccatcgtcg ccagcggcgc tggcgtcccc gtcgccaagc acggcaacta ctccgtctcc
    13981 tcgtcgtcgg gaagcgcgga cgtactcgag gaggtcggcg tcgaagtcga ggccgaaccg
    14041 cccgccgtcg aggcggccat cgaggacgac ggcatcgggt tcatgctcgc gccggtcttc
    14101 caccccgcga tgaaggccgt catcggcccg cggaaggaac tcgggatgcg aaccgtgttc
    14161 aacgtcctcg gtccgctgac caaccccgcg ggcgctgacg cccaaatcgt cggcgtctac
    14221 gaccctgacc tcgtgccggt cctcgctcgg tcgctctcca agatgagcgt cgagcgcgcg
    14281 ctggtcgtcc acggctccgg catggacgaa atcgcggtcc acggcgagac taccgccgcc
    14341 gaggtccgcg gcgacgaaat cgaggagtac accatcacgc ccgaggacgt cggcctctcg
    14401 cgccaccccg tcgccgacgt gtccggtggc acccccgagg agaacgccga agacatgcgc
    14461 ggcatcgtcg agggagacgt gaccggcgcg aagcgcgaca tcatcctcgc caacgccgga
    14521 gccgcactct acgtcgctgg cgaggccgac tcgctcgaag acggtgcgca attggccgag
    14581 aaagccatcg aagacggcgc ggcggccgac cacctcgaac gcctccggac caccgtgcca
    14641 gcatgacgcg ggtgaaaatc tgcggactca ccgcccgcga ggacttgcgg gtcgcggtcg
    14701 aagcgggcgc tgacgccgtc ggcctgctgg tggacgtgcc ggtcgattcg ccgcgagaaa
    14761 tcgacaccca gcgagcggtc gaactcgccg aggcggcccc gccgttcgtg acgaccgtgc
    14821 tggtgacgat gccggattcg ccggagcgcg ctgtcgaact caccagcgcc gtcgaccccg
    14881 acgccgtgca ggtccacggc aacctcggcg tgggcgacat cgcgtacctg accgccaacg
    14941 tgaacgcgca ggtcctcaag gtcgtggacg ccgcggaacc cgaggacgcc cggcgctacg
    15001 acgacgtggc agacgcgcta ctggtcgatt ccgtggacga ggagggcgct ggcggcacgg
    15061 gccgcaccca cgactgggag cgcactaccg agttcgccgc cgacctcgac tcgccggtcg
    15121 tcctcgcggg cggcctgacg cccgacaacg tcgccgacgc ggttcgctcg gtcgaaccct
    15181 tcgccgtgga cgtcgccagc ggcgtcgagc ggagcggtac cgacgcgtcc gagacagcac
    15241 cctcgacgac cggacgtaag gacccggacg cggtcgccga cttcgtggcg aacgcgaaac
    15301 gagcgtattc gactccgaca ccatgaagcc gggacgcaag cagttcgccg acctcgcggg
    15361 aggcgacgac ctctcggtag tccgaatcga agccgaactc gacgtagaga ccacgcccct
    15421 gtcggcctac gcggcgctga ccgggcgctc gaccgacgcg gacgccgccg agtacgcctt
    15481 cctgctcgaa agcgccgaga agaccgcttc cagcgacccc gacggcgcgt tctcggccga
    15541 acagtccggc gaccgccacg cccgctactc ctacgtgggc tacgaccccg acgccgtcgt
    15601 gacagtcgcc cccgacgaga ccaacgtcga gtcgctcggc ggccgggccg ccaaattcgt
    15661 cgctggcgac cactccggcg acgcgctcga cgccctacgg tcggccatgc ccgacgccga
    15721 acgccgcgga ttccccgagg gcgaccgcca gcacttcgag ggcggtctgg tcggctttct
    15781 ggcctacgac gcggtgtacg acttctggct cgacgagcga ggagtcgagc gcccggagtc
    15841 cagattcccc gacgctcagt tcgtcctcaa cacgaagacg gtcgcgttcg accaccgcgc
    15901 cggaaccgcc tcgctggtgt tcacgccgct ggtcggcccg gacgacgacc ccgcggaaat
    15961 ctacgacgac ctccgggcgg aagccgagcg cgtggccgac ctcctcgaat cggccagttc
    16021 gcccgagacc ggcgggttcg tctgcgagtc ggagactgct ggcccgcgcg aggagtacga
    16081 agaggcggtc cgcaccgcga aggaacacgt cctcgacggc gacatctatc agggcgtcgt
    16141 ctcccggaag cgagagctga ggggcgacgt ggacccgctg gggttctacg acgcgctccg
    16201 ggaggtgaac ccctcgccgt acatgtatct cctcggctac gacgaccgga ccgtggtcgg
    16261 cgcgagtccc gagacgctgg tgtcggtccg cggccgcgag gtcatggcga accccatcgc
    16321 gggaacctgc tcgcgggggt cgagtccggt cgaggaccgc cgcctcgcgg gcgagatgct
    16381 cgccgacgag aaagagcagg ccgaacacac gatgctggtg gacctcgctc gcaacgacgt
    16441 gcgccgggtc agcgaacccg ggagcgtaca ggtcgaggag ttcatgaacg tcctcaagta
    16501 cagccacgtc cagcacatcg agagtaccgt gacggggcga ctcgccgcgg gttcggacgc
    16561 cttcgacgcc actcgtgcgt ccttcccggc gggcaccctc tcaggtgcgc cgaagattcg
    16621 tgcgatggaa ctcctcgacg acctcgaacg ctcggcgcgc ggcctctacg gcggcggcgt
    16681 cggctactac tcgtggtcgg gcgacgccga cttcgccatc gtcatccgga ccgcgaccat
    16741 cgagtcggac gcagatgcct ctccgccgga ccgcatcacg gtgcaggccg gtgcgggcat
    16801 cgtcgccgac agcgacccca gcgcagagta cgaagagacc gagaagaaga tggacggcgt
    16861 gctgaccgct ctcgaccgca tcgaagagtc gcgcaagcgt cgtcccaccg accccgacga
    16921 gacggaagcg ccgggggtga gtcgatgacc gcgagcgtcg agggcgaccg caggcagtcg
    16981 cccgccgccg aggatctgca agtcctcttc gtggacaact tcgactcgtt cacctacaac
    17041 ctcgtggagt acacgagcga acacgccgag acggaggtgg tccgcaacac ggcctcgctg
    17101 gccgacgtgc gggaggccga cccggacgcc atcgtggtct cgccggggcc gggacacccg
    17161 gcgaacgagc gcgacgtggg cgtcactctc gacgtgttcc gcgaggtcag ccccgaggtg
    17221 ccgacgctcg gggtctgtct cggactggaa gccgcggtct acgcctacgg cgggtcggtc
    17281 ggacgcgctc ccgagccagt ccacggcaag gccttccccg tggaccacga cgggcgaggc
    17341 gtctacgcgg ggctggaaca ggggttccgc gccggtcgct accactcgct ggttgcgacc
    17401 gaggtccccg actgcttcga ggtgaccgcg acgaccgacc acgaaggtga ggaactggtg
    17461 atgggtgtgc gccaccgcga gcatcccatc gagtgcgtcc agttccaccc cgagagcgtg
    17521 ctaaccgcgg tcggccacga cgtgattcgg aacttcgtcc gtgaagtggc gtagattcgt
    17581 ctctcggact acgattggct ccgccttttc aggttagtcg gactggcagt tgatgaggtc
    17641 atcgacactg ctgactgact cgccagctcc ctgcccacaa ctgcgcgaaa cgtccggtaa
    17701 aggttggtcc cgtgctcaga tttaaatctt cgtggcggtc gctctgtccg gggataagac
    17761 aggatattat ttcctaaagg aatatttttt tatataaatg gatttctatt tcttttccga
    17821 cgcgctcgac tacagcaaca cgcccgccgt gtagagcgcc ccgacgacca cgatagcgac
    17881 cagaagcagt ttccacgcga cgctcaggac gatgcgcccg attagtacga tggccgcgag
    17941 cgcgacgagg ccgaccagca gttccccgag tggcgacgcg agcagtcccg ccgcgagtgc
    18001 gatgttcata ctaaaatcaa ggctcctcga ccaccgtaaa cgtatcgacc gattaacatt
    18061 ctgccatgtt ccgaaaccgg tggcgggcgg ccggataggt tgggcctact caagtactcc
    18121 tccggttggc tgactacttt cgccacggtc tgggtactct tattagggtg cgggtgatac
    18181 atttgagcga caacccatag ccgtgaatcc gccttttata cggtcggatt ccggtgcgat
    18241 taatttcgac cagaggcatc aaagtgcaaa ttaaattgga gtagtccaac tgggacagca
    18301 aaggttaaac cggaggcttc agaatgaaat cgccgtcacg aatgatacga actacaccac
    18361 tcgcgggagc ggaattcgac agacagagac ccgaggtgac ccacgcatga gcggtgcggg
    18421 cgaactcacg gccgacgaac tcactctccc catcaagcga accgaaggcg agacgctcga
    18481 agagcggctc accggcaacg cctatcacaa catcctcccg gcgcgctacc tccggaagaa
    18541 cgccgacggg gacctcatcg aggagcagga ggacctcttc ccgcgcgtcg ccgagaacat
    18601 cgcgctggcc gaggccgtct acgaggccga gaaccgcgac gaggagatta cggtcacgcc
    18661 cgaccagctc aagcccgacc accctcggcg cgacgaactc gccgcggaag tgttcggcaa
    18721 gggcaccacg gccgacgacg acgccgaaac caccctctcc atctacaacg tcaacaagtt
    18781 cgcttacgag acggtggttc cggacctccc cgacgagatt cgagaccacg tcgaggacgt
    18841 gcgcgaggag ttccagacgc tgatggagga tctctcgttc atgccgaact cgccgacgct
    18901 gatgaacgcg ggcgacgaac tccagcagct ctcggcctgc ttcgtggact cgccgggcga
    18961 cgacatcacc gacatccacc agaccgccaa ggaggccgcc gaggtcttcc agtccggcgg
    19021 cggcatgggc tacgccttct ggaaactccg accctacggc gacgcggtgg gtagcacggg
    19081 cggcatcgcc tccggcccca tcaccttcat gcggacctat gaccagatgt gcgagaccat
    19141 cgcgcagggc ggtgcccggc gtggtgccca gatgggcgtc atgcgcgtct cccaccccga
    19201 cgtcatccag ttcattcacg ccaagaacaa ggacgtgagc ctcgcgcaca ccctccgcct
    19261 gaacgacccc gacgactaca cccacaactc gttcaaggag gccctcgaag aggcccgcga
    19321 actcatcgac gacgagggtc gcgtgcccaa gcacctccgg aacgccgccg agggtcacct
    19381 ctcgaacttc aacatctcgg tcggcgtcac cgacgacttc atggacgcgg tcaagaacgg
    19441 cgaggagttc accttcacca accctcgcac ggaggagccg cacatcgcca ccgaacacac
    19501 caaggaactc tacgagatgt tcggcctcgg cgaacacgtc gaggtcggcg aggagctttc
    19561 ggttccggcc gaactcgtct gggaccgcat cgtggacggt gcccacgaga acggcgaacc
    19621 cggcgtcatc tacctcgaac gggtcaacaa ggagcactcc ttcgacgtgg agaaacaccc
    19681 cgaccaccag attctggcga ctaatccgtg cttgactggt gatatggaag tcgccgttgc
    19741 tggtgatgaa gtgtcagttc caatttcgga gcttacagat gagaatgaac tagaactgtt
    19801 ggcactgact gatgatgggg aagtagtgac tgcacgagga gttaatccac gtcttacaaa
    19861 gaaggatgca gacatccttg aattgaccac tgataaagga acaaaactcc gcctcactcc
    19921 agatcatgag gtccagttgg aaagtggtga ctgggtagag gctcaaaacc ttgagcaagg
    19981 tgatgagctt gctttccacg aatccggaaa ctggtctttc actaccgaac ccaaaaccct
    20041 cagcgatggt ggcgatacgc taacttggtc acaagagaac ggaggcattc cagaacatgg
    20101 gtttgaaaca gtctgcgttg aatctattac ggaagccgga acggaagacg tgtacgacat
    20161 taccgttccg agacatcaca acttcttcgc tggcaatgtt agtgaacagg atgggccacc
    20221 cctcttcgtc aacgttcaca actgcggtga acagccattg gaggagtacg aggcctgtaa
    20281 cctcgggcac atcaacctct cgacgctggc cgacacagac gccc
//
