LOCUS       NZ_SNUX01000002        22619 bp    DNA     linear   CON 22-JUL-2024
DEFINITION  Shouchella lehensis strain DSM 19099 Scaffold2, whole genome shotgun
            sequence.
ACCESSION   NZ_SNUX01000002
VERSION     NZ_SNUX01000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Shouchella lehensis
  ORGANISM  Shouchella lehensis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Shouchella.
REFERENCE   1  (bases 1 to 968217)
  AUTHORS   Liu,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-MAR-2019) Microbiology, Fujian Academy of Agricultural
            Sciences, Wusi Road, Fuzhou, Fujian 350003, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 12-MAR-2019
            Assembly Method                   :: SMRT Link v. 5.1.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 140.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004375095.1-RS_2024_07_22
            Annotation Date                   :: 07/22/2024 02:06:54
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,132
            CDSs (total)                      :: 4,031
            Genes (coding)                    :: 4,012
            CDSs (with protein)               :: 4,012
            Genes (RNA)                       :: 101
            rRNAs                             :: 9, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 73
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 7 of 19
            Pseudo Genes (incomplete)         :: 12 of 19
            Pseudo Genes (internal stop)      :: 4 of 19
            Pseudo Genes (multiple problems)  :: 4 of 19
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:25:09
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 440214
            Orig. end                         :: 462833
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            SNUX01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22619
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="3"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22619
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22619
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12619](+)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12619
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            429..587
                     /locus_tag="E2L03_RS20325"
     CDS             429..587
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="E2L03_RS20325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_166740227.1"
                     /transl_table=11
                     /translation="MKPDWYTYAITIATMTFVGFTSFNNTAAALIFGIGSGSIFGWVIA
                     SILKIKQ"
     misc_feature    611..625
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: medium, score: 23.46"
                     /tool="antismash"
     gene            640..1305
                     /locus_tag="E2L03_RS08295"
                     /old_locus_tag="E2L03_08295"
     CDS             640..1305
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020618915.1"
                     /locus_tag="E2L03_RS08295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="E2L03_08295"
                     /product="hypothetical protein"
                     /protein_id="WP_134258908.1"
                     /transl_table=11
                     /translation="MFRSYRQWKRRKKVNKVKEGDGHALKPFRFWQPLTRSLFYLKLRN
                     HESEDHVYAVNVHFFSEDNTAELYLNGKHIATSSLPAAFPVPGGVIEVGTTDYGLSRMH
                     YVEDGGQREYVLQPDKRSGEGLRMRFDQRFPILSKSIGRSAVMVLLVSLLLGLPQLVEL
                     VTSIPWIHEQIGTFQSPITLPDWANTTLIVAAVLAGIERALLLKNHWLIDMETGYWDN"
     gene            1347..1574
                     /locus_tag="E2L03_RS08300"
                     /old_locus_tag="E2L03_08300"
     CDS             1347..1574
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="E2L03_RS08300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="E2L03_08300"
                     /product="hypothetical protein"
                     /protein_id="WP_134258909.1"
                     /transl_table=11
                     /translation="MEKKVKRITSPFIQASMLTVLPIIWARGIEWQAVQVGFFNQPFLY
                     SISAFMLGMWGLFLLLMVSGNKKETETTLS"
     gene            complement(1600..2307)
                     /gene="chbG"
                     /locus_tag="E2L03_RS08305"
                     /old_locus_tag="E2L03_08305"
     CDS             complement(1600..2307)
                     /EC_number="3.5.1.105"
                     /GO_function="GO:0016811 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds, in linear amides
                     [Evidence IEA]"
                     /GO_process="GO:0000272 - polysaccharide catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="chbG"
                     /inference="COORDINATES: protein motif:HMM:NF002559.0"
                     /locus_tag="E2L03_RS08305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="E2L03_08305"
                     /product="chitin disaccharide deacetylase"
                     /protein_id="WP_166740228.1"
                     /transl_table=11
                     /translation="MSTVVFNADDFGLSRGVNYGILDCHLHGVVSSTTMLVNMPGTRHA
                     VALAQQHPSLRVGVHLALTIGTPLAENVPSLTNQDGQFRSLLEQRNERLIDPADVLREW
                     TKQIETFFEFGLTPSHLDSHHHMHNWAHLRPVIEELASVYQLPWRHYFEETPHQTQMYT
                     EAFDERFYKQGVTHKALDRILDEHRGVQSLEIMCHPAYADTTLTTTSSYVSERLKETDV
                     LMTYTLPDGWTLK"
     gene            complement(2324..3034)
                     /locus_tag="E2L03_RS08310"
                     /old_locus_tag="E2L03_08310"
     CDS             complement(2324..3034)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016202586.1"
                     /locus_tag="E2L03_RS08310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="E2L03_08310"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_241741822.1"
                     /transl_table=11
                     /translation="MSAMHQQIKENIIQKIEANEYAPQSQLPTEAEFCETYGVSRTTVR
                     TALQQLSQEGYVVRRQGQGTFVAEPKIRTNLSQTITSFTEQVTSQGKKPFIKVLSLQVI
                     PADEELSDLLQTDANAAIQKIIRVRYVDEKPLQYEIAYVPWSIAPGITEEQCSVSLYST
                     LRDHYSVRIARTEEHLQLTTMDPFIATHLLSEEQTPCFYLETLAFLEDGKIAEHSQTYF
                     HGERASFQIERHYS"
     misc_feature    complement(3193..3204)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.16"
                     /tool="antismash"
     gene            3253..4569
                     /locus_tag="E2L03_RS08315"
                     /old_locus_tag="E2L03_08315"
     CDS             3253..4569
                     /EC_number="3.2.1.86"
                     /GO_function="GO:0008706 - 6-phospho-beta-glucosidase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727187.1"
                     /locus_tag="E2L03_RS08315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="E2L03_08315"
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="WP_038476680.1"
                     /transl_table=11
                     /translation="MMLKLVIIGGGSSYTPEIIEGMIDRHDQFPVTEIALVDIEKGKQK
                     LDVISRLAKRMVKKSGKDITITASLDRRNALKNADFVTSQIRVGGLKAREKDERIPLSY
                     GALGQETNGAGGIFKALRTIPVLLEVSKDMAELCPNAWLINFTNPAGMVTEALLKYGSH
                     KRVIGVCNIPFNMRTGVAEILGCQTEDVEIEFIGLNHFVFGRRVLVKGVDYTSIVIERL
                     KDPSNQYSPANIVSEGWSSTFLSSFMMLPNPYHSYYFKGAEMLEKSLKEYWENGTRAEV
                     VQQVEEELFKKYDDKELTEKPTELEKRGGAFYSDAACNVMTSIYTNKGDIQTVNVQNNG
                     TISDLPNDAVIETNAVMGGEGPRPISIGTLPLSIRGIIQLMKNMEELVIEAAVKGDRER
                     LYQALVINPLVREETLAKDLMEELLDAHKEDLPQFYQQV"
     gene            4585..5865
                     /locus_tag="E2L03_RS08320"
                     /old_locus_tag="E2L03_08320"
     CDS             4585..5865
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA]"
                     /GO_process="GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019244162.1"
                     /locus_tag="E2L03_RS08320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="E2L03_08320"
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="WP_038476683.1"
                     /transl_table=11
                     /translation="MMQWLERNVVPVAGKIGAQRHLVAIRDGFVSVIPLIIIGSFAILL
                     NNFPLPTIDRYQAFMMGIFGENFTMFGGNIWDASYAILALLVTMAISYHLARSYHVDGL
                     AAAILSVSTFVMLSPFTEDWGLSLAWTGSQGLFVALFNALIVTELFRVLVNSRFTIKMP
                     QGVPEGVTKSFRSLIPFLIILIGLSLLQMFMTLVVQLSVHELIFEWIQTPLLKLSNSLP
                     AALIVVFLNHFLWFFGLHGTNIMSPIMEGVYLSASITNTELVQAGASIFGNELAIVTKA
                     FFDAYVFMGGSGTTLALIAAIFIVAKTSHYRTVGKLGAPGAAFNINEPIMFGMPIVLNP
                     SLLIPFVLSPILLTIISYFAISFGFVAKTAVAIPWTTPPIISGFLVSGHWSGVVLQLFN
                     LTLATLIYIPFIRLSERAQERIEKENG"
     gene            5880..6200
                     /locus_tag="E2L03_RS08325"
                     /old_locus_tag="E2L03_08325"
     CDS             5880..6200
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010897083.1"
                     /locus_tag="E2L03_RS08325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="E2L03_08325"
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="WP_038476686.1"
                     /transl_table=11
                     /translation="MTRTLEEISFTLILHSGNARSFAMEAIQAAKAGEFEQAAGKLKEA
                     EDAFVTAHHGQTELLQQEAQGNGVTPSILLIHAQDHLMTSMTVKEMAVELVELYQRLPK
                     GV"
     gene            6205..6513
                     /locus_tag="E2L03_RS08330"
                     /old_locus_tag="E2L03_08330"
     CDS             6205..6513
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003325264.1"
                     /locus_tag="E2L03_RS08330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="E2L03_08330"
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="WP_038476689.1"
                     /transl_table=11
                     /translation="MNILLVCSAGMSTSMLVSKMREAAEVKGVTCEIDAVSASQLNDHL
                     EKVDVLLIGPQVRYMQAQITKQAEPYNVKVDLINQMDYGMMKGENVLNQAIQLAEGK"
     gene            6665..7054
                     /locus_tag="E2L03_RS08335"
                     /old_locus_tag="E2L03_08335"
     CDS             6665..7054
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019422969.1"
                     /locus_tag="E2L03_RS08335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="E2L03_08335"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_134259173.1"
                     /transl_table=11
                     /translation="MHEAPNPKAYIELRLEAGLSEKSVEAAEIGLRHSLYAVTLYDGDR
                     LIGMGRIIGDGGAFFQIVDIAVKPTYQGKGLGSVIMKHLTDYLDQHTLPGSYVSLIADG
                     EAEHLYKKFAFKHTAPRSQGMYRSY"
     gene            7175..7342
                     /locus_tag="E2L03_RS20330"
     CDS             7175..7342
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="E2L03_RS20330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_166740229.1"
                     /transl_table=11
                     /translation="MNRFERELFRRELLFLKAMRRKVTGNEARFTEMLDDQIKHLEAIL
                     HEETENVLSD"
     gene            complement(7492..7674)
                     /locus_tag="E2L03_RS08340"
                     /old_locus_tag="E2L03_08340"
     CDS             complement(7492..7674)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="E2L03_RS08340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="E2L03_08340"
                     /product="hypothetical protein"
                     /protein_id="WP_134258910.1"
                     /transl_table=11
                     /translation="MMLEVAILFAILVVLGFLGAPLMKTWKYLIRQMIIGSIVLMAFMI
                     VLFFYEFIEGGFMRF"
     gene            8159..9013
                     /locus_tag="E2L03_RS08345"
                     /old_locus_tag="E2L03_08345"
     CDS             8159..9013
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002150926.1"
                     /locus_tag="E2L03_RS08345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="E2L03_08345"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_038476695.1"
                     /transl_table=11
                     /translation="MTVLLEMENISKTFKRKHVLKNVTLDVPAGSIVGFVGDNGAGKST
                     TFKTILGLIKKDEGTVRLFGEEVHGQQPSMREQVGVVFDAINLPAELTIKQLNKVFVKM
                     YSSWDQEGFDRLLETFHLPTDKKVKEFSRGMSMKLSVAVALSHNAKLLLLDEATGGLDP
                     SSRKELLEELTRFVEENKGGILLSSHIMSDIEKIADHLVFIKDGEIILTEKREVIQNQY
                     AIVEMNENDLSTVEPEHIVTSYKEKDAFVVLISDKRVVPDNVPVNELTLEDLSVFLARG
                     EKK"
     gene            9010..9666
                     /locus_tag="E2L03_RS08350"
                     /old_locus_tag="E2L03_08350"
     CDS             9010..9666
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024741.4"
                     /locus_tag="E2L03_RS08350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="E2L03_08350"
                     /product="ABC-2 transporter permease"
                     /protein_id="WP_038476698.1"
                     /transl_table=11
                     /translation="MNALLLTSYYLVYRSLFMYVGISIFVAALVLGFGQESMHPFVVLL
                     TLLLVSIPAMEVIKHESKSGYDKFVLTMPVNRAHIVFGHYLFYLAVLAIGIVITTVTFF
                     VYFIVVEESYMQLLVQIAPSIMLVLLIGALIFPLLYLLGPEKSDGVLIVAAGAAILVSF
                     LMERVVSNLVFERLAFNEAETSSMVVYSLTFVLIGLILYILSFLIALSVYKRKEF"
     gene            9698..9973
                     /locus_tag="E2L03_RS08355"
                     /old_locus_tag="E2L03_08355"
     CDS             9698..9973
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="E2L03_RS08355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="E2L03_08355"
                     /product="hypothetical protein"
                     /protein_id="WP_038476700.1"
                     /transl_table=11
                     /translation="MKKDTFIRDIFEYGLTLLGVNILFILTETLNLNRSFNTDGQGNWS
                     IFGFSLQDFFTENFAFYETWVFNMILVFMVVACLFMIIFRAIRRGM"
     gene            10001..12619
                     /gene="lanKC"
                     /locus_tag="E2L03_RS08360"
                     /old_locus_tag="E2L03_08360"
     CDS             10001..12619
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF038151.1"
                     /locus_tag="E2L03_RS08360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="E2L03_08360"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_166740230.1"
                     /sec_met_domain="micKC (E-value: 8.8e-139, bitscore: 459.8,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 5.7e-17, bitscore: 57.8,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 7.3e-21, bitscore:
                     70.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLEGNFLYHQYLKVDSEHYGKIKKGEGGELTVTNENKGMYSVH
                     SDEASVWTHYQIDGVHLPTQGWKIHITASKNDAQTVLNDVAMVCMERKLVFKHLKDRES
                     FMKMNSKNANRASSGKFITIYPLNDEQFIQLLDVFADVTKKYEKGPYILNDKRWKDSNV
                     FYRYGGFKTILNEDGEHCIYDDTGQLIPDQRNPFYQVPTFMETYDAYLDSLNIKDDLLL
                     NEETTKLNEYTMETSLSYSNAGGVYLATRKKTNEKVIIKEARPVAGLDGIGRDALERQK
                     IELDALTTLKDVSGVVNVMDHFQAWEHYFIVEEYIEGSDLRSWLVQNYPFVGSVDLNLY
                     GEEIMSIMTNLYHIMEDMHQKGIAMGDIQPANVILTSSGEVKLIDFETASSVYSTDKPG
                     MATTGFISKEINVAGARDWFGYLKLLRYLSLPILTSDTLETYLAPIQLEWIKNQYPSHI
                     YKQFIDLFEKAANQIRSYQSDIQYQWQLDVDEQTEDLQQIVNKLIKGLGQHVTDDERFI
                     NGDIRQYELKDGKFNILNGGSGAALTLYRSNHCVEKVDKWINTHLLAKLPTVQNIGLFS
                     GLAGIGTLLYERGYTESAQQVIQKINQTDERNDLTLRSGLSGVGLFYISLYLETNKTEY
                     LDYAESIQDRIDSARKKQPSLKTNDWSAVPIGLIDGVSGIALFYAALYSVTSNEDYLQQ
                     AIQFIAEDLDKTQKDEESDMLQTLDENNRLLPYLSGGSIGIGIAIWYVNHVSGKQLFKE
                     EFDSILNVSKIRCTISGGLFDGAGGFLLVPSLVEDRQAQWDCTKDVIQLAHLFLIEKED
                     AYLYPGNFSYRLSDDLFSGSSGIILAFQSIMKKNPLYWLPLINVETFLSSTKGSALKKV
                     R"
     gene            12671..12808
                     /locus_tag="E2L03_RS20335"
     CDS             12671..12808
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018887349.1"
                     /locus_tag="E2L03_RS20335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class III lanthipeptide"
                     /protein_id="WP_166740231.1"
                     /transl_table=11
                     /translation="MNQVLELQKLAHEVDGQGQWSVEKSPATVTITTTAVGWSTASNDC
                     "
     CDS_motif       12671..12715
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNQVLELQKLAHEVD"
                     /locus_tag="E2L03_RS20335_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       12716..12808
                     /prepeptide="core"
                     /locus_tag="E2L03_RS20335_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="-2.30"
                     /molecular_weight="2903.1"
                     /monoisotopic_mass="2901.4"
                     /core_sequence="GQGQWSVEKSPATVTITTTAVGWSTASNDC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNQVLELQKLAHEVD"
                     /leader_location="[12670:12715](+)"
                     /alternative_weights="2921.1"
                     /alternative_weights="2939.1"
                     /alternative_weights="2957.2"
                     /alternative_weights="2975.2"
                     /alternative_weights="2993.2"
                     /alternative_weights="3011.2"
                     /alternative_weights="3029.2"
                     /alternative_weights="3047.3"
                     /alternative_weights="3065.3"
     gene            12839..12976
                     /locus_tag="E2L03_RS20340"
     CDS             12839..12976
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018887349.1"
                     /locus_tag="E2L03_RS20340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class III lanthipeptide"
                     /protein_id="WP_166740232.1"
                     /transl_table=11
                     /translation="MNQVLELQKLAHDSDGQEQWSVEKSPATITTTRTVIGWSTASNSC
                     "
     CDS_motif       12839..12895
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNQVLELQKLAHDSDGQEQ"
                     /locus_tag="E2L03_RS20340_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       12896..12976
                     /prepeptide="core"
                     /locus_tag="E2L03_RS20340_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="-3.30"
                     /molecular_weight="2585.8"
                     /monoisotopic_mass="2584.4"
                     /core_sequence="WSVEKSPATITTTRTVIGWSTASNSC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNQVLELQKLAHDSDGQEQ"
                     /leader_location="[12838:12895](+)"
                     /alternative_weights="2603.9"
                     /alternative_weights="2621.9"
                     /alternative_weights="2639.9"
                     /alternative_weights="2657.9"
                     /alternative_weights="2675.9"
                     /alternative_weights="2694.0"
                     /alternative_weights="2712.0"
                     /alternative_weights="2730.0"
                     /alternative_weights="2748.0"
                     /alternative_weights="2766.0"
     gene            13013..13150
                     /locus_tag="E2L03_RS20345"
     CDS             13013..13150
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018887349.1"
                     /locus_tag="E2L03_RS20345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class III lanthipeptide"
                     /protein_id="WP_166740233.1"
                     /transl_table=11
                     /translation="MNQVLDLQKLAHDSNGQGQWSVEKSPATITTTTTAVGWSTASNGC
                     "
     CDS_motif       13013..13069
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNQVLDLQKLAHDSNGQGQ"
                     /locus_tag="E2L03_RS20345_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       13070..13150
                     /prepeptide="core"
                     /locus_tag="E2L03_RS20345_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="-0.10"
                     /molecular_weight="2458.7"
                     /monoisotopic_mass="2457.2"
                     /core_sequence="WSVEKSPATITTTTTAVGWSTASNGC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNQVLDLQKLAHDSNGQGQ"
                     /leader_location="[13012:13069](+)"
                     /alternative_weights="2476.7"
                     /alternative_weights="2494.7"
                     /alternative_weights="2512.7"
                     /alternative_weights="2530.7"
                     /alternative_weights="2548.8"
                     /alternative_weights="2566.8"
                     /alternative_weights="2584.8"
                     /alternative_weights="2602.8"
                     /alternative_weights="2620.8"
                     /alternative_weights="2638.9"
     gene            13185..13322
                     /locus_tag="E2L03_RS20350"
     CDS             13185..13322
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018887349.1"
                     /locus_tag="E2L03_RS20350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class III lanthipeptide"
                     /protein_id="WP_166740234.1"
                     /transl_table=11
                     /translation="MNQVLDLQKLAHEVDGQGQWSVEKSPATVTITTTAVGWSTASNDC
                     "
     CDS_motif       13185..13229
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNQVLDLQKLAHEVD"
                     /locus_tag="E2L03_RS20350_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       13230..13322
                     /prepeptide="core"
                     /locus_tag="E2L03_RS20350_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="-1.90"
                     /molecular_weight="2903.1"
                     /monoisotopic_mass="2901.4"
                     /core_sequence="GQGQWSVEKSPATVTITTTAVGWSTASNDC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNQVLDLQKLAHEVD"
                     /leader_location="[13184:13229](+)"
                     /alternative_weights="2921.1"
                     /alternative_weights="2939.1"
                     /alternative_weights="2957.2"
                     /alternative_weights="2975.2"
                     /alternative_weights="2993.2"
                     /alternative_weights="3011.2"
                     /alternative_weights="3029.2"
                     /alternative_weights="3047.3"
                     /alternative_weights="3065.3"
     gene            13354..13491
                     /locus_tag="E2L03_RS20355"
     CDS             13354..13491
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018887349.1"
                     /locus_tag="E2L03_RS20355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class III lanthipeptide"
                     /protein_id="WP_164468423.1"
                     /transl_table=11
                     /translation="MNQVLELQKLATHSNDHGQWSVEKSPATVTITTTAVGWSTASNDC
                     "
     CDS_motif       13354..13410
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNQVLELQKLATHSNDHGQ"
                     /locus_tag="E2L03_RS20355_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       13411..13491
                     /prepeptide="core"
                     /locus_tag="E2L03_RS20355_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="-0.50"
                     /molecular_weight="2532.7"
                     /monoisotopic_mass="2531.3"
                     /core_sequence="WSVEKSPATVTITTTAVGWSTASNDC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNQVLELQKLATHSNDHGQ"
                     /leader_location="[13353:13410](+)"
                     /alternative_weights="2550.8"
                     /alternative_weights="2568.8"
                     /alternative_weights="2586.8"
                     /alternative_weights="2604.8"
                     /alternative_weights="2622.8"
                     /alternative_weights="2640.9"
                     /alternative_weights="2658.9"
                     /alternative_weights="2676.9"
                     /alternative_weights="2694.9"
     gene            13580..14410
                     /locus_tag="E2L03_RS08365"
                     /old_locus_tag="E2L03_08365"
     CDS             13580..14410
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024880.4"
                     /locus_tag="E2L03_RS08365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="E2L03_08365"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_124741293.1"
                     /transl_table=11
                     /translation="MDKLLEVVKSPEVFAEGSQDIWLDPDRADFVLQSHLDETMDGASK
                     DAHFIQQSIDLISEIAPLTNYQSILDLGCGPGLYSEKLAEKGYSVTGIDFAENSIEYAR
                     KEAEKKNLSIDYHCGDFLTINYEEEFDLTLLIYQIFGILNPDERKKVLSNMYRALKPGG
                     FVLLDVLSDKSFADFEESREWSLSSKNSMLSRKKHLGLISTEKYPNNVSLQKTVLVFED
                     GEIVNYHYWNQYFSVEDLRQEIEEAGFTLEQVYADVNGETYKADGEFIAAVLRK"
     misc_feature    13620..13636
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 23.25"
                     /tool="antismash"
     gene            14525..16279
                     /locus_tag="E2L03_RS08370"
                     /old_locus_tag="E2L03_08370"
     CDS             14525..16279
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002150914.1"
                     /locus_tag="E2L03_RS08370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="E2L03_08370"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_134258912.1"
                     /transl_table=11
                     /translation="METLSYKQFVGIFTTYRPSRMLLTIAFTLSLVQTGLSLVIPLIAM
                     DLVNLLIEESFNGLLLVGLVLLFVTQVVLSGLSLYLMIYIGEKVIVRLRDDLWNRVVRL
                     PLTFYDKNNSGEIMSRITNDTNVMKNFFIDHLVPFVTGLISIIGSFIILFVLNWSMALL
                     FLIIFPLAFFVIKPLGKRMYSVSRDLQQETASFQGDLSRVLGDVRLVKFSVAEKQEAAE
                     GTKRATKLYHYGLSTGKILAIVAPLMTAIILLVLVMIIGYGGYQVATGSLSAGALVAVV
                     FYIFQIINPLSMMAQFFTQAQKAMGATERVYLLLQEEHEGSRDPVKEPVRKKQHTFRGI
                     RFSNVGFSYDPERSILKNISFTAEKNHVTAIVGPSGTGKTTMFSLVERFYAVEEGDILF
                     NNDSIYSYTLEEWRRKIAYVSQESPIMSGSIRKNVTYGLKEAKSDQTIYEALGKANLMS
                     DIMGLPKGLDTEVGERGVRLSGGQRQRMAIARAILRDADILLLDEATAHLDGQSEALVQ
                     DALNELMRERTTLIIAHRIATVQNANNIVVVENGEVTDQGIHEDLYKRNTLYHQLVNRQ
                     MLSNNYGA"
     misc_feature    14527..14538
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.87"
                     /tool="antismash"
     gene            complement(16409..16867)
                     /locus_tag="E2L03_RS08375"
                     /old_locus_tag="E2L03_08375"
     CDS             complement(16409..16867)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024515.4"
                     /locus_tag="E2L03_RS08375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="E2L03_08375"
                     /product="FixH family protein"
                     /protein_id="WP_134258913.1"
                     /transl_table=11
                     /translation="MRLFFTIMSMTVFLSACSFTSHNPEAYTDFQPLQVRVELPDSVSE
                     GGKQTIYASVSQGEEEITDADLVRFEVWSNNHEQHEYVTATSEGNGIYAVEIDFTQEGL
                     YFAKAFTQVDDLYAMPTKRFAVGKITPEEAEYLLNGSSQPFSNDHAHH"
     gene            complement(16880..18238)
                     /locus_tag="E2L03_RS08380"
                     /old_locus_tag="E2L03_08380"
     CDS             complement(16880..18238)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009791008.1"
                     /locus_tag="E2L03_RS08380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="E2L03_08380"
                     /product="PepSY domain-containing protein"
                     /protein_id="WP_038476707.1"
                     /transl_table=11
                     /translation="MKTDPPRSLKRYGTVWRWHFYAGLIIAPILLLLAITGGIYLFKGT
                     IEASIYSEYYDVRPNQDGVTYPPSELIANALTAHEEIETVTSYSPSEEATRSVAIGASF
                     EDGASGTVFMNPYTGESLGVLLDQNRVMERLIELHSELMLGTFGDRVVELTASWTIILI
                     ASGLYLWWPRRSKPTLYGVWLPRVRKGKRVLVRDLHAVPAAWLSIGLLFFVLTGMLWTG
                     FWGNGVQHLATSTGQGYPPSIWVGDAPQSLTEDVAESAWAAQKLPVPLSGNAQGYEQVS
                     IDDVVTTGLHRELHPSYTVYFPRSETGSFTLSAFPDQARDEATMYVDQYTGAVLADYRY
                     DDYGLVGKWMATGITIHKGLEFGLLNQLFGLLICIGLVGIIVSGFFLWRRRKPQQHMGA
                     PKAHSIRHNRALLVILLLFAVVFPLVALSLLVVFLLDVFLIQKNKRLKAFFHA"
     gene            18554..18718
                     /locus_tag="E2L03_RS08385"
                     /old_locus_tag="E2L03_08385"
     CDS             18554..18718
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018922693.1"
                     /locus_tag="E2L03_RS08385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="E2L03_08385"
                     /product="YvrJ family protein"
                     /protein_id="WP_078440252.1"
                     /transl_table=11
                     /translation="MENLPDWAILLGNFGFPTLVAVYLLIRFEKRIEHLTDAIRELERS
                     THQQNGGKR"
     gene            18718..19407
                     /locus_tag="E2L03_RS08390"
                     /old_locus_tag="E2L03_08390"
     CDS             18718..19407
                     /EC_number="3.5.1.28"
                     /GO_function="GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA]"
                     /GO_process="GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018922694.1"
                     /locus_tag="E2L03_RS08390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="E2L03_08390"
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_055735729.1"
                     /transl_table=11
                     /translation="MELKQDFIPQSNSNRPQTALRPTHITVHETANTSNGANAEMHARY
                     VKGADAQARQVSWHVTVDDTQAIQHLPFNEVGWHAGANGNRQSIGIEICVNRDGNFPQA
                     RANAISLVRRLMNELSIGINSVVTHQHWTGKNCPANLLPSWNEFIADVRAGTSPEPAPP
                     MEGRLLRVIVDSLWVYNRPDWNARYTTVSRNEVFTIAEQLTVNGSRMYRLKSGLYITAN
                     PSYVQLI"
     misc_feature    19600..19609
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 17.8"
                     /tool="antismash"
     gene            19782..21113
                     /locus_tag="E2L03_RS08395"
                     /old_locus_tag="E2L03_08395"
     CDS             19782..21113
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1273: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006828573.1"
                     /locus_tag="E2L03_RS08395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="E2L03_08395"
                     /product="hemolysin family protein"
                     /protein_id="WP_134258914.1"
                     /transl_table=11
                     /translation="MEVSIFINLLLIVLFLALTAFFVASEFAVVKIRSSRIDQLIAEGN
                     KQATVAKTITQNLDYYLSACQLGITVTALGLGALGKPAVSSLMYPLFDFFNVSDSLSSA
                     ISYAVAFLLVTYLHVVIGEMAPKTLAIQFSEKMTLLLSEPLYWFGKLMYPFILTLNGAS
                     RLLLRVFGVKPLGHDQAYTEEELKIIMAQSYAGGAIDKEELQYMENVFSFDEHVAKDIM
                     VPRTEMITIHEGMAIEELVALMDRYNYTRYPVIEDGDKDNILGVVNAKKMLQAIVAGKD
                     VSIKSYMRELPFIFEATSIQDVMHKMQKEKVHMAVIIDEFGGTAGLVTMEEVIEELVGE
                     IRDEFDRDEESDIEQVGPNDYLINGRVLLNDLEEQFGLVFHDREHVDTIGGWLLQNSHV
                     MDGPIEGIQMEVEGHVWSVVEADEHHVKKVKWTQPQPVKLTQAT"
     gene            21155..22213
                     /locus_tag="E2L03_RS08400"
                     /old_locus_tag="E2L03_08400"
     CDS             21155..22213
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1273: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018887050.1"
                     /locus_tag="E2L03_RS08400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="E2L03_08400"
                     /product="hemolysin family protein"
                     /protein_id="WP_134258915.1"
                     /transl_table=11
                     /translation="MDPFISINLTLVALFILLTGLFVGGEFAILKVRMSRLDQLVSEGN
                     KKAVLAKKVAHELDYYLSACQLGITITALVLGALGEPTVQNILRPVFDYYSVPDALATA
                     MSYAIALAIVTFLHVVIGELAPKTLAIQFPEKMTLLLAPPLYWFGVIMGPFIRILNGSA
                     RKLLGWFGVKPAGHETVYSEEELKLIVSDSYNSGQINQTELAYLENIFSFDGRTLSKIM
                     IPKEQVVTLQENMEIDDILTTIEQQGYTRYPVVNQEGTRIVGFVNTKEMLTSIAAGRAN
                     GIDSYLHHIPRVKESLIIQDVFLKMKATRTHMVMVTNDQGDISGLVTMEDILSEIVGDL
                     EEEDYDNVGLVT"
ORIGIN
        1 aatgaagcga tgaaagaggc gacacgtcaa tcgattgact tcttggaaca tcattacggt
       61 atgaatcgag caaaagccct tgcttactta agtgcagcga cagattttga agtttcccaa
      121 gtagtggatc gaacgaaggg gattaatggg aagattcgaa aagctgattt tgaaaaaagg
      181 ctgccgaatg aattggcagc aacaacagaa ggtggacatc taccacaaac atccaccaac
      241 tatgttgcct ggataattgg tggcttaagt attgttggag cagcttttgc acttggtaga
      301 agaaagaaac gatctgtata agaaaaagag gctcagcacc atcgctgtgt ctctttttct
      361 ttttatgtaa atgaaacatt ttgtgccagt aaccgtagaa cataaaaagg aaacaaggag
      421 gagacagcat gaaaccggac tggtatacct atgcgattac catagcaacg atgacatttg
      481 ttggcttcac ttcttttaat aacactgctg ccgccctcat attcggcatt ggaagtggga
      541 gtatttttgg ctgggtcatt gcctctattc tgaaaataaa acaatgattc tttactgtta
      601 tcctatttgt ttatcaagtt gaaaaaagga gcccttttta tgtttcgttc ctatcggcaa
      661 tggaaacgcc ggaagaaagt aaataaagta aaggaaggcg acggtcatgc cttaaaacca
      721 ttccgttttt ggcagccatt aacccgctct ttattttatt taaaacttag gaatcatgaa
      781 agtgaagacc atgtgtatgc agtgaacgtt cattttttta gcgaagataa cacggcagag
      841 ttatacctta atggtaagca tattgccacc tcaagtcttc cggcagcttt ccctgtacct
      901 ggtggtgtca ttgaggtcgg aaccacagat tatggattaa gtcgaatgca ttatgtagag
      961 gatggtggtc aacgagaata cgtactacag cctgataagc gctcaggtga aggactacgc
     1021 atgagatttg accaacgctt ccctatctta agcaaaagca taggacggtc tgctgtaatg
     1081 gtattactcg tctctcttct acttggacta ccacaattag tagagctcgt tacgagcatc
     1141 ccttggatac acgaacaaat cggcaccttt caatctccta taacactacc tgattgggca
     1201 aatacaactt taattgttgc tgctgtccta gctgggattg agcgcgcact actgttaaaa
     1261 aatcattggc ttattgatat ggaaacgggc tattgggata actaatgcaa gtctaaagga
     1321 gtgtaagcgc cattgtacag cttgtcttgg agaaaaaagt aaagcggatt acgtctccat
     1381 ttattcaagc atctatgtta acggttttgc caattatatg ggcaagaggt attgaatggc
     1441 aggctgttca agttggcttt ttcaatcaac catttctcta ctctatatca gcatttatgc
     1501 ttggtatgtg gggcttattc ttgttactaa tggtaagtgg aaataaaaaa gaaacggaaa
     1561 ccacactctc ttaaaacaaa ggtgagtgtg gttttatggt tacttgagag tccatccatc
     1621 tggtaatgta tacgtcatta aaacatctgt ttcttttaaa cgctcagaga cataagaaga
     1681 agtggtggtt aacgtcgtgt ctgcataagc tgggtgacac ataatctcca aagattgtac
     1741 gcctctatgt tcgtcaagga tacgatctaa cgctttatga gtgactcctt gtttgtaaaa
     1801 cctttcatca aatgcctctg tatacatctg agtttggtga ggcgtctctt caaaataatg
     1861 ccgccaagga agttgataaa cggatgctag ttcctctatt actgggcgca aatgagccca
     1921 attatgcatg tgatgatggc tgtctaaatg actaggcgtt aacccgaatt cgaaaaacgt
     1981 ttcaatttgc tttgtccatt ctcgtagcac atcggctgga tcaatcagac gttcgtttcg
     2041 ttgttccaga agagatctaa attggccatc ctgatttgta aggcttggaa cgttttctgc
     2101 taaaggtgta ccaattgtta aagcaagatg aactccaaca cgcaagctag ggtgctgctg
     2161 tgcaagggca acagcatgac gcgtaccagg catattcaca agcatggtcg tagatgacac
     2221 gaccccatgt aaatggcaat ctaaaatacc gtagttaact cctcgtgata atccaaaatc
     2281 atctgcatta aatacaacag tagacatatt ccctaaacct ccattaactg tagtgtcgtt
     2341 caatttgaaa actcgctcgt tccccatgaa aataggtttg cgaatgctcc gcaatttttc
     2401 catcttctaa gaaagctagc gtttccaaat aaaaacacgg tgtctgttct tcagatagaa
     2461 gatgtgtagc aataaaaggg tccatagttg ttaactgaag atgttcctca gttcgcgcaa
     2521 tacgaacact gtagtgatct cttagtgtgg aatacaagga aacggagcat tgctcctcag
     2581 taatacctgg agcaatagac caaggaacat aagcaatctc atattgcaaa ggcttctcgt
     2641 cgacataacg aacgcgaatg attttttgaa tggcagcatt tgcatccgtc tgtagtaaat
     2701 cggacaactc ttcatcagcc ggaatcactt gtaatgacaa tactttaatg aaaggttttt
     2761 ttccttgtga agtgacttgt tctgtaaaag aggtaatcgt ttgggataaa ttggtgcgta
     2821 ttttcggttc tgcaacaaag gtaccttgtc cttgtcttcg aaccacataa ccctcttgac
     2881 taagttgttg tagagcagtt cgaacggtag tacgactcac accatatgtt tcacaaaact
     2941 cagcttctgt gggaagttgt gattgaggtg catattcatt ggcttctatc ttttgaataa
     3001 tgttttcttt gatttgctgg tgcattgcag acattggcat gacccctcca gattctatac
     3061 ctttattgta tcataaatga tgggaagttt tcatacaaag gtaatgacaa aaaagagaaa
     3121 tgcttttaaa gttgttatta caaataatgc tgtacatttc ttatttgtta tgataaattg
     3181 tagttgtatt aagaaagcga tttcaaataa tagttatacc tacaaataga gtaataacag
     3241 gagaggggct ttatgatgtt gaagcttgtc atcataggtg gaggatctag ctatacgcca
     3301 gaaattatag agggcatgat tgaccgtcat gatcaatttc cagtgacgga aatagcgcta
     3361 gtggatattg agaaaggaaa acaaaagtta gacgttatct cacgtttagc aaagcgaatg
     3421 gtgaaaaaat caggaaaaga cattacgatt acagccagtc ttgaccgacg aaacgcatta
     3481 aagaatgctg acttcgtgac aagtcaaatt cgagtggggg gattgaaagc aagagaaaaa
     3541 gacgaacgaa ttccactttc ttacggcgct ttagggcagg aaacaaatgg tgcaggagga
     3601 atctttaaag ccttgcgaac gataccggtt ttgttagagg tatctaagga tatggctgag
     3661 ctttgtccaa atgcatggct tatcaacttc acgaatcctg ctggaatggt aacagaagct
     3721 ttgttgaaat atggttctca taaacgcgtc attggcgtgt gtaacattcc atttaatatg
     3781 cgaacaggtg tggcagaaat tctaggctgc caaacggaag atgttgaaat tgaatttatt
     3841 ggcttaaatc attttgtatt tggtcgtcgc gtgcttgtaa aaggagtgga ctatacatcg
     3901 attgtgattg agcgattaaa agatccatca aatcaatatt ctccagcaaa tatcgtatca
     3961 gaaggatggt cgtctacatt tttatcttct tttatgatgc tgccgaatcc ttaccatagc
     4021 tattacttta aaggggcaga gatgctagag aaaagtttaa aagagtattg ggagaatgga
     4081 acacgggctg aagtcgtcca gcaagtagaa gaagagctct ttaaaaaata tgacgataaa
     4141 gagttaacag aaaagcctac cgaacttgag aaaagaggag gggctttcta tagcgatgcg
     4201 gcttgtaacg ttatgacaag tatctataca aataaaggcg atattcaaac tgttaacgtt
     4261 caaaataatg ggaccatatc agacttaccg aacgatgctg tcattgaaac caatgctgtc
     4321 atggggggag aggggccacg accaatttca ataggaacgc ttccgctctc aattcgaggc
     4381 atcattcaat tgatgaagaa tatggaggaa ttggtcattg aagcagctgt aaaaggcgat
     4441 cgtgagcgct tgtatcaagc gttagtcatc aatccacttg ttcgagaaga aacgcttgca
     4501 aaagatttaa tggaagagtt attggacgca cataaagaag atttgccgca attttatcag
     4561 caagtataaa aagggggaat ttctatgatg caatggttag aaagaaatgt tgtgccagtg
     4621 gcggggaaaa ttggcgcaca aaggcactta gttgccattc gagatggatt tgtcagtgtt
     4681 attccgttaa ttattattgg ctcgtttgct atcttactta acaatttccc attaccgaca
     4741 atcgatcgat atcaagcgtt tatgatgggg atattcggtg aaaatttcac catgttcggc
     4801 ggaaatatat gggatgcctc ttatgcaatc ttggctctcc ttgttacgat ggccatttcc
     4861 tatcatctag ctcgttccta tcatgttgat gggttagcag cagcaatctt atccgtttcc
     4921 acattcgtta tgctatcgcc gttcactgag gattggggac tctcactagc atggacagga
     4981 tcacaaggcc ttttcgttgc gttgtttaat gccctcattg taactgaatt atttcgagtg
     5041 cttgttaatt caagatttac gattaaaatg ccacagggag tacctgaggg tgtaacgaaa
     5101 tcttttcgct cattaattcc atttcttata attctcatag ggcttagctt actgcaaatg
     5161 tttatgacgt tagtcgttca actaagcgtg cacgaattaa tctttgaatg gattcaaacg
     5221 ccattactaa aattatcaaa ttcattacca gcagcactta tcgttgtgtt tcttaatcat
     5281 ttcttatggt tcttcgggtt acacgggaca aatattatgt caccgattat ggaaggtgta
     5341 tacttatcag caagtattac aaatactgag cttgttcaag caggagcgag tatttttggg
     5401 aacgagctag cgattgtaac aaaagcattc tttgatgctt acgtttttat gggtggttcg
     5461 ggaacaacat tggcacttat cgccgcaatc tttattgtag caaaaacgtc ccattaccga
     5521 acggttggga aattaggtgc accgggagca gcgtttaata ttaatgaacc tattatgttc
     5581 ggtatgccca ttgtgttgaa tccgtcactg ttaattccat ttgttttatc accaatacta
     5641 ttgaccatca tttcttattt tgcgatttcc tttggatttg ttgcgaaaac ggcagttgcc
     5701 attccttgga caacaccgcc tattataagc ggattccttg tttcagggca ttggtcaggg
     5761 gtggttttac agctctttaa cttaacactt gccacactta tctatatacc atttattcgc
     5821 ttatctgaac gtgcacaaga acgaattgaa aaagaaaacg gttaagaagg agtaccatca
     5881 tgacaagaac acttgaagaa atttcattca ccctcatttt gcattcggga aacgctcgct
     5941 cttttgccat ggaagccatc caagcggcaa aggctggaga atttgagcaa gcggcaggta
     6001 aattaaaaga agccgaggat gcatttgtga cggctcacca tggacaaacg gaactgctcc
     6061 aacaagaagc gcaaggaaac ggggtcaccc cttccatttt attaattcat gcacaagatc
     6121 acttaatgac ctcgatgaca gtaaaagaaa tggctgttga attggttgaa ctctatcaac
     6181 gcttaccaaa gggagtgtaa aaagatgaat attttactcg tatgttcagc tggaatgtct
     6241 actagtatgc tcgtttcaaa aatgagagaa gcagctgaag tgaaaggcgt aacgtgtgaa
     6301 attgatgccg tatccgcttc acagttaaac gaccatttag aaaaagtgga tgtcctgtta
     6361 atcggtccac aagtacgtta catgcaagca caaattacga aacaagctga accgtacaac
     6421 gtcaaagtcg atctgattaa tcaaatggac tatgggatga tgaaaggtga aaacgtactg
     6481 aatcaggcaa tacagctcgc tgaagggaaa taaggtgtac aaaaagtata ggcaagttgc
     6541 ctatactttt tttgtgtata atggaggaat agggaagtaa gcaggaatgt ttacaagtat
     6601 gttcagcgat tttgaaggct agaaaacgaa taaagtggag ggaaagaaat tggattatac
     6661 agtgatgcat gaagccccaa atccgaaagc ttatattgag ttacgactgg aagcgggatt
     6721 aagtgagaaa tcggtagagg cagctgaaat cggacttcgt cattctttat atgcagtgac
     6781 gttgtacgac ggagataggt taatcggtat gggcagaatt attggagatg gtggcgcatt
     6841 ttttcaaata gttgatattg cagtcaagcc tacgtatcaa ggaaaagggt taggcagtgt
     6901 tattatgaag caccttactg actaccttga tcaacacaca ctgcctggtt cctatgttag
     6961 ccttattgca gatggggaag cagagcattt atataagaaa tttgcgttta aacatacagc
     7021 cccccgatcc caaggaatgt accgttcgta ttaaagaggt tcgcctattt gttcactgga
     7081 tggtagaaag atagccaaaa gtgtggtttt acgtatggga agaggggtaa tcaatacaca
     7141 taggtatcaa tcatgtttaa ggaggatatc tatcatgaat cgctttgagc gagaactgtt
     7201 tcgccgggaa ttactatttc ttaaagcaat gaggagaaaa gtaaccggta atgaagctcg
     7261 ctttacggag atgttagatg accaaattaa gcatcttgaa gcgatccttc atgaagaaac
     7321 agagaatgtc ttatctgatt agtgttaaag gataggtgaa cgcctatcct acatatcaat
     7381 gcgagaggat cttccttaac gtgattgatc gctaatcaat ggcttgctct gattcagaga
     7441 agaaggccca tgtatccttg catgggcctt ctttcttgtc tatatttaac actaaaaccg
     7501 cataaagccg ccttcaataa attcatagaa aaagagaacg atcataaaag ccattaggac
     7561 aatggacccg ataatcatct ggcgtataag gtatttccat gttttcatta atggggcacc
     7621 aagaaagcct aacacgacca gtatggcaaa gagtatcgca acctctaaca tcatacatca
     7681 cctctagatg acagttcttt cctgagctcg aacgacttat actagtctat gcatctctta
     7741 ttgcttgttt cataaaaaag acaatgaaga caacgtatgt aatatgctat caggctgtat
     7801 agtaaaagaa taaggtcatt ttcgtgtttt gaaacatgcc gctgtggtat ataaaaatag
     7861 agatgagagg cgtcatatag cttctgagcc tgtttttttc aagtttaacc ataaagagta
     7921 gccagaaaaa tccctgtttt cgtaaaaata ataaaaaaat tgaaattttg tggttttgaa
     7981 acaatttgct gtggtatata aatacataaa tcaagacagt gccgatttga agtgtgtttt
     8041 atattcgtta taggttgtca tgcttctttt actataagcc aatatggaga atgtgaaatg
     8101 tattttcaat atataaaaaa ttaataatat tttttatata tttttaggag gataaaaaat
     8161 gactgtactt cttgagatgg aaaatataag taaaacattt aaacgtaaac atgttcttaa
     8221 gaatgttacc ttagatgttc ctgctgggtc aattgttgga tttgtaggcg ataacggagc
     8281 aggaaagtcg actactttca aaacgatttt aggtttaatc aaaaaagatg aaggaacggt
     8341 tcgattattt ggagaggaag tacatgggca gcaaccatct atgagggaac aagttggcgt
     8401 tgtctttgat gccattaact tgcctgctga actgacgatt aaacaattaa ataaagtgtt
     8461 tgtgaaaatg tatagtagct gggatcaaga aggatttgat aggttgttag aaacgtttca
     8521 tttgccgact gataaaaaag taaaagagtt ttcaagagga atgtcgatga agctatccgt
     8581 ggctgtagca ctatctcata acgcaaaatt gcttctattg gatgaagcga caggagggct
     8641 tgatccatct tcacgtaaag aattgctaga ggaactaact cggtttgttg aggagaataa
     8701 aggtggcatt ctgttatcct ctcatattat gagtgacatt gagaagattg ctgatcacct
     8761 tgtttttata aaagatggcg aaattatctt aacggaaaag agagaagtca ttcaaaatca
     8821 atacgcaatc gtagaaatga atgaaaatga cttatcgaca gtagaaccag agcatattgt
     8881 aacatcgtat aaagaaaagg atgcgtttgt ggtattgatc tctgataaaa gagttgtacc
     8941 ggataacgta cctgttaatg aattaacact agaagattta agcgttttcc tagcgagagg
     9001 tgaaaagaaa tgaatgcatt attactaaca agttattact tagtctaccg tagtttattt
     9061 atgtatgttg gcatatccat ttttgtagct gcgttggtgt tagggtttgg tcaagaatcc
     9121 atgcatcctt tcgttgtatt gcttacgcta ttattagttt ccatccctgc aatggaagta
     9181 attaagcatg aatcaaagtc tggctacgat aaatttgtgc tgaccatgcc agttaatcga
     9241 gcacatatcg tgtttgggca ttatcttttt tacttagcag tactcgcaat tggaattgtc
     9301 attacaacgg taacgttttt cgtgtatttt attgtagtgg aagagtctta catgcaactc
     9361 ctcgtgcaaa tagcgccttc tattatgctt gtattgttaa ttggagcact tatttttcct
     9421 ctgctttatt tattaggacc agaaaagtca gatggtgtct taattgtggc ggcaggtgca
     9481 gccattttgg ttagcttcct gatggaacga gtggtttcca atcttgtatt tgaacgactc
     9541 gctttcaatg aggcagagac gtcatcaatg gttgtttatt cactgacctt tgtgctgatt
     9601 gggctcatcc tttatatcct ttcttttctc attgctttaa gtgtttataa gcgaaaagaa
     9661 ttttaattca cgattacgtt taaacgggag gcctattttg aaaaaagata cattcatacg
     9721 ggatattttt gaatatggtt tgacgttact aggtgttaat attctattta ttcttacgga
     9781 aacactgaac ctcaatcggt catttaatac ggatggccaa ggaaattgga gcatctttgg
     9841 tttttcctta caagattttt ttacggaaaa ttttgctttc tacgaaacat gggtatttaa
     9901 catgattctg gtgttcatgg ttgtagcatg tctatttatg attattttta gagccattag
     9961 acggggaatg taatgtttcg ctatggagag gaaagggagg atgaaaaaat tggaaggtaa
    10021 ctttctttat caccagtatt taaaagtaga ctcagagcat tacgggaaaa taaaaaaagg
    10081 cgaaggaggt gaattaacgg ttacgaacga aaataagggc atgtattctg ttcatagcga
    10141 tgaggcatcc gtttggacac actatcaaat agatggcgtg catttaccga cccaaggatg
    10201 gaagattcac ataactgcct ctaagaatga tgcccaaacc gttcttaatg acgtagcaat
    10261 ggtttgcatg gaacgtaagc tagtgtttaa gcacttaaaa gaccgagaga gctttatgaa
    10321 aatgaattca aaaaatgcga atcgtgcctc atcaggcaaa tttataacga tttatccact
    10381 caatgatgaa caatttatac aattattaga tgtttttgct gacgtaacaa agaagtatga
    10441 gaaaggtccc tatattttaa atgataagcg ttggaaggat agcaatgttt tttatcgata
    10501 tggaggattt aaaacaatat taaatgaaga cggggaacat tgtatatacg acgataccgg
    10561 tcaattaatc cctgatcaac gcaacccatt ctatcaagta ccgacattta tggaaacgta
    10621 tgatgcttat ttagattcat taaacataaa agatgatcta cttttaaacg aagagacgac
    10681 taaacttaac gaatatacga tggagacatc tttaagctac agtaacgctg ggggagttta
    10741 tttagccaca agaaagaaaa caaatgaaaa agtaatcatt aaagaggcta gaccagtagc
    10801 tggcttagat ggaataggtc gagatgcgtt agagaggcag aagatcgaac tagatgcact
    10861 aacgacctta aaagatgtat ctggagtcgt gaatgttatg gatcacttcc aagcgtggga
    10921 acactatttt attgtggaag aatacattga gggctcagat ttaagatcat ggttagtaca
    10981 aaactatcct tttgtaggta gtgtagactt gaacctgtat ggtgaagaga tcatgtccat
    11041 tatgacgaac ctttatcaca ttatggagga catgcaccaa aaaggcatag caatgggtga
    11101 tattcaacca gcaaatgtga ttctgacttc aagtggagaa gtcaagttaa ttgattttga
    11161 aacggcgtct tccgtctatt ctactgacaa acctgggatg gcgactactg gttttatctc
    11221 gaaagaaatt aacgtcgcag gtgcaaggga ttggtttggc tatctaaaat tactacggta
    11281 tctttcttta ccaatcctaa cgtcggatac attagaaaca taccttgccc ctatccagtt
    11341 agagtggatt aagaaccagt atccaagtca catttataag cagtttatcg atctatttga
    11401 aaaagcagcc aatcagattc gttcctatca aagcgatatt caatatcaat ggcagttaga
    11461 tgtggacgag cagacggaag acttacaaca gattgtgaac aaactaataa aaggattagg
    11521 tcaacatgta accgatgatg aaaggttcat taatggtgat atccgtcagt acgagttaaa
    11581 ggatgggaaa ttcaatatac taaatggcgg gagtggagcc gctttaacct tgtatcgttc
    11641 aaaccactgt gtagaaaaag tagataagtg gatcaacact catttattgg ctaagcttcc
    11701 aactgttcaa aacatcggtt tgttttcagg actggctgga atcggtacgt tgctttatga
    11761 aagaggatat acagaatcgg cccagcaagt aatccagaaa ataaatcaaa cagacgaaag
    11821 aaacgatcta actttacgct ctggtctctc tggtgtcggt ttgttttata taagtctgta
    11881 tctggaaacg aataaaaccg aatatttgga ttatgctgaa tctattcaag atagaattga
    11941 cagtgcaaga aaaaagcagc catcattgaa gactaacgat tggtctgctg taccgatagg
    12001 gttaatcgat ggcgtatctg gtattgcttt gttttacgct gcgctctatt ctgtgacatc
    12061 gaatgaggac tatctgcaac aagccattca attcatagca gaagacttgg ataaaacgca
    12121 aaaagacgag gaatcggata tgctgcaaac attggatgag aacaatcgat tattaccgta
    12181 tttatctgga ggttcaatcg gaatcggtat agccatttgg tatgtaaatc atgttagcgg
    12241 caaacaactg tttaaagaag agttcgactc tattttgaat gtctcaaaga tcagatgcac
    12301 cattagtggt gggctcttcg atggtgcagg cgggtttctg ctagtaccat ccttagtaga
    12361 agatagacaa gcacaatggg actgtacaaa agatgtcatt cagctggcac atttgttttt
    12421 aattgaaaaa gaagatgctt atctctatcc aggtaatttt tcctatcgat tatcggatga
    12481 tttgttttcc ggtagttctg ggatcattct agccttccaa tcgattatga agaaaaatcc
    12541 attgtattgg ttacctctca taaatgtgga aaccttttta tcaagcacga aaggatcagc
    12601 actgaaaaaa gttcgttaag gttgatcaac atgtggacaa gtcgattatt ctgtaaagga
    12661 ggtgagaacg atgaatcaag tattagaatt acagaaacta gcacatgaag tagacggtca
    12721 aggacaatgg agcgtcgaaa aatcaccagc aaccgtgacg atcacgacaa cagcagtagg
    12781 ttggtcaacg gcgagtaatg attgttaagc attggcaagg ataagaggag gtaccaacat
    12841 gaatcaagtt ttagaattac agaaactagc acatgattca gacggtcaag aacaatggag
    12901 tgtcgaaaaa tcaccagcaa ccattacaac aacaagaacc gtcataggct ggtcaacggc
    12961 aagtaatagt tgttgaggct cgttggaaat ttgtaaagga ggtgaaaacg cgatgaatca
    13021 agttttagac ttacaaaaac tagcgcacga ttcaaatggt caaggacaat ggagcgtcga
    13081 aaaatcacca gcaaccatta caacgacgac aacggcagta ggttggtcaa cggcaagtaa
    13141 cggttgttaa aagtaggtgg gaatctttta aggaggtgac gaacatgaat caagtcttgg
    13201 acttacaaaa attagcgcat gaagtagacg gtcaaggaca atggagtgtt gaaaaatcgc
    13261 cagcaactgt gacgatcacg acaacggcag taggttggtc aacagcaagc aacgattgtt
    13321 aatagtagat cttttatcat aggaggtacg tacatgaatc aagtactaga attacaaaag
    13381 ctggcaactc attcaaacga ccacgggcaa tggagcgttg aaaaatcacc agcaacagtg
    13441 accataacaa caaccgcagt aggctggtca acagcaagca acgattgtta attatgatgc
    13501 aagttgttag tctgtttggc taacaacttg catacattat agtcggtttg caataaaaac
    13561 tcaaataagg gtggtagaaa tggacaagtt attagaagtt gtaaagagtc ccgaagtgtt
    13621 tgcagaaggg tcgcaagata tttggcttga tccggatcgt gctgattttg tcttacagtc
    13681 acatctggat gaaacaatgg acggtgcaag taaagatgca cattttattc agcagtccat
    13741 tgatcttata agtgagatag cgccactaac aaactaccaa tctatacttg atcttggttg
    13801 tggaccggga ctgtattcag aaaagctagc tgagaaagga tatagcgtta caggcataga
    13861 ctttgctgag aattccattg agtatgcgag aaaagaagcg gagaaaaaga acctatccat
    13921 tgactatcac tgtggagatt tcctaactat taactatgaa gaagaatttg acttaaccct
    13981 attaatctat caaatctttg gtattttgaa ccctgatgaa cggaaaaaag tactgtcgaa
    14041 tatgtataga gctcttaaac ctggaggatt cgtgttgcta gatgtattgt cagacaaaag
    14101 tttcgcagat ttcgaagaat caagagagtg gagtctctca agtaaaaata gtatgttatc
    14161 aagaaaaaag catttagggt tgatctccac tgaaaagtat cctaataatg tctcacttca
    14221 aaaaaccgtc ttagtgtttg aagatgggga aatcgttaac tatcattatt ggaatcaata
    14281 ctttagtgtg gaagacttaa gacaagagat tgaagaagct ggattcacac ttgaacaagt
    14341 gtatgcagac gtgaacggtg aaacgtataa agcagatggt gaatttatag cggctgtttt
    14401 acggaaataa acaagcattt cgttgataaa gatttctata tcgtttaaaa gggacaaaaa
    14461 gtttgtgtct atttcttttt tcaatgaacg actgaaactc taactatgaa aagagacttt
    14521 cactatggaa acgttatcgt ataaacaatt tgttgggatt tttactacct ataggccgtc
    14581 tcggatgctc ctaacaattg cctttacact ttccttggtt caaacagggc tgtcgttagt
    14641 cattccatta atagctatgg atcttgtgaa cttgctcatc gaggaatcgt ttaatgggct
    14701 cctacttgtt gggttagtgc ttttgttcgt tactcaagtt gtcttatctg gtctatcctt
    14761 atacttaatg atttatatcg gtgaaaaagt gatcgtacgt cttcgggatg atttgtggaa
    14821 tcgagttgta cgattgcccc tgacgttcta tgacaaaaac aattccggcg aaattatgag
    14881 ccgcattacc aacgacacca atgtgatgaa aaattttttt attgatcatt tagtcccctt
    14941 cgttacaggg ctcatttcaa taatcggttc attcatcatc ctctttgttt taaactggtc
    15001 tatggcgctg cttttcttaa ttatttttcc attagcgttc tttgtgataa agcctcttgg
    15061 aaaacgaatg tacagcgttt caagagacct acagcaggag acggcttctt ttcaaggcga
    15121 cctaagtaga gtgctaggag acgttcgact agtgaaattt tctgttgctg aaaagcaaga
    15181 ggcagctgaa gggactaagc gcgctactaa actctatcac tatggattat ccaccggaaa
    15241 aatactagca attgtggctc cgttaatgac agcaatcatt ctacttgtac tcgtaatgat
    15301 tatcggatat ggagggtatc aagtagccac aggaagcctt tcagcaggtg cactggtcgc
    15361 tgtcgttttt tacatctttc aaattattaa tccactttcc atgatggcac agttttttac
    15421 gcaagcgcaa aaagcgatgg gtgcgactga gcgggtttac ttattattgc aggaagaaca
    15481 tgaggggtca cgtgacccag tgaaagagcc tgtgagaaaa aaacagcata cgttcagagg
    15541 tattcgtttt tcaaacgtcg gtttttcgta cgatccagaa agaagcattc taaaaaatat
    15601 tagctttacg gcagagaaaa atcatgtaac cgcaatagta ggacctagtg gaactggtaa
    15661 aacaaccatg ttttcgctag tggaacgatt ctacgctgta gaggaaggtg atattctctt
    15721 taataatgac tcgatctact cctatacatt agaagagtgg agaaggaaaa ttgcctatgt
    15781 aagtcaagag tcgccgatta tgagcggaag cataagaaag aatgtaacct atggattaaa
    15841 ggaagcaaaa agcgatcaga ccatttatga agccttaggc aaagcgaatt taatgagtga
    15901 catcatgggg ctaccaaaag gactggacac agaggtagga gaacgagggg ttcggttatc
    15961 tggtggtcaa agacaaagaa tggccattgc aagagccatc ttaagagacg cggacatcct
    16021 tttactcgat gaagcaacag cacacttaga tgggcaatcg gaagcgcttg ttcaagacgc
    16081 attgaacgag ttaatgagag aacgaacaac gttaatcatc gcccacagaa tcgcaactgt
    16141 tcaaaacgca aacaacattg tagtagttga aaatggagaa gtgacagatc aagggattca
    16201 tgaggattta tacaagagaa atacattata tcatcagcta gtgaatagac agatgttatc
    16261 gaacaactat ggggcgtaac gaaagggtag tacaagtagc gatgaaaagg aaaccgtaca
    16321 aagaacgaaa gacgaatgtc cgccaacggg atcattcgtc tttttcatgc atcgtctatt
    16381 cttgcatcct taaaagagtg tgcatgttct aatggtgtgc atgatcgttt gaaaatggtt
    16441 gtgaagagcc gtttagtaaa tactccgctt cttcaggtgt gatcttgccg acagcaaaac
    16501 gctttgtcgg catcgcatat aagtcatcaa cttgtgtgaa ggctttggca aaatagagcc
    16561 cttcctgtgt aaaatcaatt tccactgcat agatcccatt tccttcagaa gtagccgtta
    16621 catattcatg ttgttcatga ttattggacc agacttcaaa tcgaacaaga tccgcatctg
    16681 tgatctcctc ctctccttga gagacagacg cataaatcgt ttgtttccct ccttccgaga
    16741 cggaatcagg taattcgact cttacttgaa gcggttgaaa gtctgtgtac gcttcagggt
    16801 tatggctagt aaaagaacag gcagacagga aaacagtcat gctcatgatg gtaaagaata
    16861 atcgcatgtt atcaacctcc tatgcgtgga aaaacgcttt gagacgcttg tttttttgaa
    16921 taaggaaaac gtctaataag aacacaacga gaagagaaag ggcaacaagt ggaaacacaa
    16981 cagcaaataa gagtagaatg acgagcaaag cccggttatg acgaatggaa tgtgcttttg
    17041 gagcacccat atgttgttga ggcttccggc gtctccataa gaaaaaccct gatacaatga
    17101 tgccaactaa gccgatacaa atgagtaagc cgaacaattg attaagaagt ccgaattcaa
    17161 gccctttatg aatcgtaatc cccgttgcca tccattttcc aactagacca tagtcatcat
    17221 accgataatc ggcgagaaca gcacctgtat attgatccac atacatggtc gcttcgtctc
    17281 ttgcttggtc aggaaaggca gaaagcgtga aggagcctgt ttcactcctt ggaaaataaa
    17341 cggtgtagct cggatgtaat tcccggtgca accctgttgt gactacatca tcaattgaaa
    17401 cctgttcata gccttgggcg ttcccagaaa gcggtacagg taatttctgt gcagcccagg
    17461 ctgattctgc tacatcctcg gttaaggatt gcggagcatc acctacccaa atagacgggg
    17521 gatacccctg ccctgtactt gtggctaaat gctgcacacc atttccccaa aaaccagtcc
    17581 acaacatccc tgttaaaacg aaaaacaaga ggccgatgga tagccacgca gcaggcactg
    17641 cgtgtaaatc gcgaacaaga acacgcttgc cctttcgcac ccgcgggagc cagaccccat
    17701 agagagtagg tttggagcgt cttggccacc acaaataaag gccactagcg atcaaaataa
    17761 tggtccatga agctgtgagt tcaacaactc gatccccaaa cgttccgagc atcagctcgc
    17821 tatgtaattc aattaaccgt tccatcaccc gattttgatc caggagcacc cctaatgatt
    17881 ccccagtgta tggattcatg aagacggtgc ccgatgcccc atcttcaaat gaagcgccaa
    17941 tagcaacaga tcgggtggct tcttcactag gggaataaga ggtaaccgtt tcaatttcct
    18001 cgtgagcagt gagcgcattt gcgatcaact cactaggcgg atacgtcaca ccatcttggt
    18061 taggacgcac atcgtaatac tcgctgtaga tggaagcttc aatcgtgcct ttaaacaagt
    18121 agatgcctcc tgtaatcgct agaagaagta aaatgggtgc aatgataaga ccagcgtaaa
    18181 aatgccatcg ccaaaccgta ccataacgtt ttaacgatcg aggtggatct gttttcaatg
    18241 gtcattcctc atttcgatta taataatata atgtttgttg aactaactat acaacaagga
    18301 taacgaaata atgtgaacta attgtgtgtt taggttggga aaataaaaaa agcacctaaa
    18361 cggtttagaa acaaggcatt tccataacgt tggtcgcttt taatccttta taaagtcctg
    18421 ctggcgccgc ttgatcgtat caaacgaacc accccgactt atccttctaa atccccattt
    18481 tatacttttc tccatctcat gattgatttt ttcgcgaagc tttctctttt tctagtagag
    18541 gggggaacat catatggaaa atctacctga ttgggcaatt ttgttaggga actttggttt
    18601 tcccacgctc gtggctgttt atttactcat tcgttttgaa aaacggattg aacatttaac
    18661 agatgcgatt cgtgaactag agagaagcac acatcaacag aatggaggaa aacgataatg
    18721 gaactaaaac aagattttat cccacaatca aattcaaatc gtccgcagac tgctttacgt
    18781 ccaacgcata ttacggttca tgagaccgct aatacgtcta atggggcaaa tgccgaaatg
    18841 catgcacgtt atgtaaaggg ggcagatgct caggcaagac aagtctcatg gcatgtgacg
    18901 gtggacgata ctcaagcgat tcagcacttg ccttttaacg aagtcggttg gcacgctggt
    18961 gcaaacggga atcgccaatc aatagggatt gaaatttgtg taaaccgaga tggcaacttt
    19021 ccgcaggcac gagcaaacgc catttcctta gtgcgacgat taatgaatga gttatcaatt
    19081 ggcatcaatt cagttgttac ccaccagcat tggacaggca aaaactgtcc ggcaaattta
    19141 ttaccttctt ggaatgaatt tattgctgat gttcgagcag gtacaagccc tgaaccggca
    19201 ccacctatgg agggtcgtct acttcgtgtt attgtcgaca gcttatgggt ttacaatcga
    19261 ccggattgga atgcacgcta tacgacggtt tcaagaaatg aagtgttcac cattgccgag
    19321 caattaacag taaatggctc acgcatgtat cgtttaaaaa gcgggctcta tattacggca
    19381 aacccatctt acgttcaatt gatctaaata aaagcctgtc tcactattgt gggacaggct
    19441 tttgtaaagt ttgtgtaaat gtattttgta agatgtaacg caaacggctt tcgattacgg
    19501 gaatttgcta tactcttctt acaccaaata cgtgaggaag ctcgaacgta aaggtgttta
    19561 gccaacaata cgttaacgat agggagggac acccattggg aaggcgacgc tttttaacag
    19621 aaatcaaacg gaactagcgc aagaaacggt tgcttttcta agctgccctc tttgtcattc
    19681 ataaaagatt gaggagctaa agagaaaagt gaatctgttt ctgagagtga ctgaaacaaa
    19741 caacaattct tggaggtgaa tcccttcttt aagggaaatc attggaagta agcatattta
    19801 ttaatctctt gctcattgta ctatttttag cattaaccgc tttctttgta gcttctgaat
    19861 ttgcggtcgt caagatccga agctcacgaa ttgatcaact gattgcggaa ggaaataaac
    19921 aggcgactgt cgccaaaaca attacgcaga acctcgatta ctatttatcg gcctgtcagc
    19981 ttgggattac cgtaacagct ttaggtctag gtgcacttgg taagcctgct gtaagtagtt
    20041 taatgtatcc tttgtttgac ttctttaatg tgtcagactc cttatcatct gccatttctt
    20101 atgcggttgc gtttctactt gtgacctatt tacacgttgt catcggggaa atggcgccta
    20161 aaacattggc aattcaattc tcggaaaaaa tgactttgct tttatcagaa ccattgtatt
    20221 ggttcggtaa actgatgtac ccatttattc tgacgttaaa tggtgcctct cgtttattgt
    20281 taagagtgtt tggcgtcaag ccgcttggtc atgatcaagc gtacacagaa gaagaactga
    20341 aaattattat ggcgcaaagc tatgcaggcg gcgcgattga taaagaagaa cttcaatata
    20401 tggagaacgt cttttcattt gacgaacatg tggcaaaaga cattatggtg ccacgtacag
    20461 aaatgattac catccatgaa ggcatggcga tagaggaact agtggcgtta atggatcgct
    20521 acaactatac gcgataccca gttatagaag atggcgacaa agacaatatt cttggcgtcg
    20581 tcaacgcgaa gaaaatgctt caagcgattg ttgctggaaa agatgtatcc attaagtcct
    20641 atatgcgcga gcttccattt atttttgaag caacgagcat tcaagatgtg atgcacaaaa
    20701 tgcaaaaaga aaaagtgcat atggctgtca ttattgatga attcggtggt acggcaggtc
    20761 ttgtcacaat ggaagaagtc attgaagaat tggtcgggga aatacgtgac gaattcgatc
    20821 gggatgaaga aagcgatatt gaacaagtcg gaccgaacga ttacttgatt aacggtcgtg
    20881 tgctgttaaa tgatttagag gagcaatttg gattggtgtt tcatgatcgt gaacacgtgg
    20941 ataccatcgg tggctggctc ttacaaaaca gtcacgtcat ggatggaccg attgaaggca
    21001 ttcaaatgga agtagaaggc catgtttggt cggttgtcga agcagacgaa caccatgtta
    21061 agaaagtaaa gtggacgcaa ccccaaccag ttaagcttac tcaagcaact taaatgatac
    21121 ggaggtgaac ccttctctac atgagaagga tgaattggac ccatttatta gtataaatct
    21181 aacccttgtc gcactcttta ttcttttgac cggactgttt gtcggtggag agtttgcgat
    21241 tttaaaggtt cggatgtcaa ggcttgatca gctcgtttca gaagggaaca aaaaagcggt
    21301 tcttgctaag aaagtggcac atgagcttga ttactaccta tctgcctgcc agctagggat
    21361 taccattaca gcgcttgtgc taggtgcatt aggtgaacca actgttcaaa atatcctgcg
    21421 gcctgtgttt gactactaca gcgtcccaga cgcattggca accgccatgt cttacgccat
    21481 tgcccttgct atcgtcactt ttctccacgt ggtaattgga gaattagcgc caaaaacact
    21541 tgcaatccag tttcctgaga agatgacgct tctattagca cctccccttt actggtttgg
    21601 ggtcatcatg ggacccttca ttcgcatttt aaacggatca gcccgcaagt tactagggtg
    21661 gtttggcgtt aaaccagcag gacatgagac cgtctactca gaagaagagt tgaagcttat
    21721 cgtctcagat agttacaata gcggacaaat caaccaaact gagctagctt acttggaaaa
    21781 catcttctca tttgatggac gaacattaag caagatcatg attccgaaag agcaagtcgt
    21841 gacgttacag gaaaacatgg agatcgatga cattttaaca accattgagc aacaaggata
    21901 cacccgttat cccgttgtaa accaagaagg aacaaggatc gttggctttg taaacacgaa
    21961 agaaatgctc acaagtatcg cagcaggtcg tgccaacggg atcgattcgt acttgcacca
    22021 cataccacgt gtaaaagaat ctttgatcat acaagacgtc ttcttaaaga tgaaagccac
    22081 acgcactcat atggtgatgg tgacaaatga tcaaggtgac ataagcggtc ttgtgacgat
    22141 ggaagacatt ctaagtgaaa ttgtcggtga cttggaagaa gaagattacg ataacgtcgg
    22201 tttggtaacg taaaaaaagt gatccttttt tctaaaaggg tcactaagct ataagttttt
    22261 tttatactct taggtgcaat atatgttgag gaccttttgg accttcataa aattcattct
    22321 cgtctgcaaa tcctgttttt aaatagagat gataagcagg tatgtttctt ttattgacac
    22381 ccaatacaat ctcatcagta tcaaggagat tgtttctaat aaactcgggt aagagttgaa
    22441 ggccattctt cgctaggcct tttctttggt ttcttgaacc aattgagaag gctgtcagca
    22501 acaaagaatt aggatttttg ctgtatttaa acagcttttc gccatcgtag agcaaaataa
    22561 cctaccatta tcctgttttc aagaattaat atatgtttag tagtgtttga aacatttgg
//
