LOCUS       NZ_SNXZ01000009        12736 bp    DNA     linear   CON 20-APR-2024
DEFINITION  Labedaea rhizosphaerae strain DSM 45361 Ga0310470_109, whole genome
            shotgun sequence.
ACCESSION   NZ_SNXZ01000009
VERSION     NZ_SNXZ01000009.1
KEYWORDS    WGS; RefSeq.
SOURCE      Labedaea rhizosphaerae
  ORGANISM  Labedaea rhizosphaerae
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Labedaea.
REFERENCE   1  (bases 1 to 207576)
  AUTHORS   Goeker,M.
  TITLE     Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing
            the most valuable type-strain genomes for metagenomic binning,
            comparative biology and taxonomic classification
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 207576)
  AUTHORS   Goeker,M., Huntemann,M., Clum,A., Pillay,M., Palaniappan,K.,
            Varghese,N., Mikhailova,N., Stamatis,D., Reddy,T., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-MAR-2019) Prokaryotic Super Group, DOE Joint Genome
            Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.12.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 180.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004362825.1-RS_2024_04_19
            Annotation Date                   :: 04/19/2024 13:11:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,820
            CDSs (total)                      :: 7,753
            Genes (coding)                    :: 7,690
            CDSs (with protein)               :: 7,690
            Genes (RNA)                       :: 67
            rRNAs                             :: 3, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2 (5S)
            tRNAs                             :: 59
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 11 of 63
            Pseudo Genes (incomplete)         :: 55 of 63
            Pseudo Genes (internal stop)      :: 3 of 63
            Pseudo Genes (multiple problems)  :: 6 of 63
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 17:41:24
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 26517
            Orig. end                         :: 39253
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            SNXZ01000009.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..12736
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="hydrogen-cyanide"
                     /region_number="1"
                     /rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD) and DAO)"
                     /tool="antismash"
     cand_cluster    1..12736
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /kind="single"
                     /product="hydrogen-cyanide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..12736
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:7736](+)"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..7736
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
     gene            complement(377..1378)
                     /locus_tag="EV186_RS35055"
                     /old_locus_tag="EV186_10926"
     CDS             complement(377..1378)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020646747.1"
                     /locus_tag="EV186_RS35055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_10926"
                     /product="proline racemase family protein"
                     /protein_id="WP_133853836.1"
                     /transl_table=11
                     /translation="MRSSRVIHVVDSHTEGMPTRVVTGGIGTVPGATMFDKRRYFMANL
                     DHLRRFLMNEPHGHPAMSGAILQPPTRPDADYGVLFIEVSGCLPMCGHGTIGVATVLVE
                     TGMVAVTEPVTTIRLDTPAGLVTASVRVEDGAAKAVTLANVPSFALALDQTVRVEPWGD
                     VPYDMAFGGNFYAIVELDKLGIPFERTGKQRLLDAGMSIMEAINEQAKPVHPAHPEVTG
                     CHHVYLAAPGSTAKHSRHAMVIHPGWFDRSPCGTGTSARMAQLHARGELGLHEDFDNES
                     LLGTHFTGRLIEQGTLGDLTTVTPTITGSAWVTGIGQHFLDPSDPFPEGFEL"
     gene            complement(1378..2283)
                     /locus_tag="EV186_RS35060"
                     /old_locus_tag="EV186_10927"
     CDS             complement(1378..2283)
                     /EC_number="4.1.3.3"
                     /EC_number="4.2.1.41"
                     /EC_number="4.3.3.7"
                     /GO_process="GO:0009436 - glyoxylate catabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0071704 - organic substance metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020658768.1"
                     /locus_tag="EV186_RS35060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_10927"
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="WP_133853837.1"
                     /transl_table=11
                     /translation="MTTPAWHGVLVATALPLRSDDRTDDLAADFDGYAEHVRWLAANGC
                     DGVVPNGSLGEYQTLTPDERARVVTTAIEAAPAGFTVMPGVAAYGAAEARRWAEQAAEA
                     GAPVVMLLPPNAYRADRRAVIGHYREVAKAGLPVVAYNNPFDTKVDLVPDLLAELHGEG
                     LIVAVKEFSGDVRRLYRITEAAPGLDVLAGSDDVALELAIAGSPGWVSGYPNAFPDACV
                     RLWKAARDGDLATALPLYRTLHPLLRWDSQTEFVQAIKLSMDIVGRYGGPARPPRVPLT
                     DEHEAIVRQATEKALAEGLS"
     misc_feature    complement(2355..2365)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: strong, score: 22.4"
                     /tool="antismash"
     gene            2370..3797
                     /locus_tag="EV186_RS35065"
                     /old_locus_tag="EV186_10928"
     CDS             2370..3797
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1169: sugar
                     transport protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020658226.1"
                     /locus_tag="EV186_RS35065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_10928"
                     /product="MFS transporter"
                     /protein_id="WP_133853838.1"
                     /transl_table=11
                     /translation="MDDVAEVRGTTFSSAELAARLDRLPVSRFHYRLLAAGGLGYTFDA
                     MDGAIVAFIMPPVTKQWHLSSLETGVLGSSLLIGFLFGAFFAGVLGDRIGRKKVMVSAL
                     GLYCVASVVAAFAPTFWVLFVARVIAGVGTGAESAIIAPYLSEFVPTRVRGRYIGSLAG
                     FFAFGFVFASLLGYFIVRSSPDGWRWVQLITAVPIVMLLWWRRSLPESPRYLHVQGRTA
                     EAEKIVRDVEDSVRASTDKPLPPASSVPAETEAPVPHGRILDNLKALFQGGLRRTTFTT
                     WVYWFVAIFTYYGFFTWIPSLLVNRGFDISKSFAFSILIYLAQIPGYYSAAFISERLER
                     KWTIVLYLSGGAVAAWALANAGSSTEILVWGMVLSFFMNGNAALEYTYTSEIYPTAIRT
                     TGLGVASALGRVGGVIAPLLIGFSYSSVGFGGVFAMLLVLLVLGAVVVAVFGQRTNGRS
                     LEQIGRDTIGVERSTRG"
     misc_feature    2439..2441
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            3790..5004
                     /locus_tag="EV186_RS35070"
                     /old_locus_tag="EV186_10929"
     CDS             3790..5004
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015801578.1"
                     /locus_tag="EV186_RS35070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_10929"
                     /product="amidohydrolase family protein"
                     /protein_id="WP_243754474.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 3.7e-41, bitscore:
                     135.0, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADLVLRHVDVVHPATARVERDRRITLRDGRIAALEADDTAGLDD
                     AEFDGTGLFALPGLIDCHVHVNAMTADLGSIVDESPAYVAARASQILRGMLERGFTTVR
                     DVGGADFGLAAAVDEGIFAGPRIFFCGKALSQTGGHGDGRPRGRDMHDPAYTRPVLGRI
                     ADGVAGVRAAARDEIRRGAHHLKVMISGGCASPTDRIDSLQFSDEELRAIVDEAARAGL
                     YCAGHAYTAAAVNRGLALGFRSIEHGNLLDETSIELFLAHDAFYVPTLITYVAQVEAGA
                     ELDIAADQLAKVDQVLDGGLRALELADRAGVKIAFGTDLLGAMHRRQCDEFRLRAKVQR
                     PEAVLRGATTIAAELLRRDDLGVFAPGAVGDVVLARGNPLADVELLADPGRAIAAVVKD
                     GRLVA"
     gene            5001..6146
                     /locus_tag="EV186_RS35075"
                     /old_locus_tag="EV186_10930"
     CDS             5001..6146
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020658765.1"
                     /locus_tag="EV186_RS35075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_10930"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_279538354.1"
                     /sec_met_domain="DAO (E-value: 2.9e-71, bitscore: 234.4,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRSDVSDVIVIGAGMVGAMTAYHCAAAGLRVTVLERDAVAGGTT
                     SACEGNILVSDKEPGPELDLALLSIRRWQELADELGADSLEYQAKGGVVVAMSDDTGAG
                     LTAFTASQRAAGIDAQDVSSAQLREREPNLSPDARSGAYYPQDAQVQPMLATARLLRAV
                     RDLGGTVRTGTEVTGFVERGVATSAGIVHAEHVVNAAGTWAGQVSELAGAPVPVLPRKG
                     FILVTEPLPRTIRHKVYTAEYVANVASSDAGLETSVVVEGTKAGTVLIGASRERVGFDR
                     SMSLPVVRKLAAQAIEVFPFLADVALLRSYLGFRPYCPDHLPVLGPDPRVPGLVHACGH
                     EGAGIGLAAGTGHLIAQVLTGKEPDLDLTPFRPHRFEEAPA"
     gene            6143..6409
                     /locus_tag="EV186_RS35080"
                     /old_locus_tag="EV186_10931"
     CDS             6143..6409
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_4"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020658766.1"
                     /locus_tag="EV186_RS35080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_10931"
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="WP_208115941.1"
                     /sec_met_domain="Fer2_4 (E-value: 2.1e-26, bitscore: 85.5,
                     seeds: 114, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRFTFDGKAIPAEPGQSIGAALIAAGHRSWRRTRIDAAPRGIFCG
                     IGICHDCLVTVDGAANRRACLVEAAEDMRVTTQEGAGRAELEC"
     gene            6390..7736
                     /locus_tag="EV186_RS40630"
                     /old_locus_tag="EV186_10932"
     CDS             6390..7736
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Pyr_redox_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_BFD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020668270.1"
                     /locus_tag="EV186_RS40630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_10932"
                     /product="FAD/NAD(P)-binding oxidoreductase"
                     /protein_id="WP_133853840.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 3e-22, bitscore:
                     72.8, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_BFD (E-value: 5e-08, bitscore: 26.9,
                     seeds: 211, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPNSSAERNEYDVAVIGAGPAGLAAAAAAADTGVSVALVDSGPRP
                     GGQYWRHRTGDDGTHHHDWAEFTRLRARIREVDHLAEHAVWHIEPGFTVHATGRDPVRA
                     RRLVLAPGAHDRQLPFPGWTLPGVYTAGGVQALLKGHGVLAGKRIVVAGTGPFLLAVAA
                     GLLDAGAGVAGVFEAGTPAGFARHPLAVAGALGKLGEGAGYLRVVGRRYRTRTMVIAAH
                     GTGELSGVTVAKVDANWQVVPGTERDVACDALAVGYGFTPQLELPLQLGCATRLDADGS
                     LVATADDRQMSTVEGVFLAGEVCGVGGSALAVTEGLIAGRHAAGVSAGSRLLRRRRAQR
                     RFAGALHQAFPLRRGWLDRVGADTVVCRCEEVRHRAVTAAVDDLGATDPRTVKLLARPG
                     MGLCQGRVCGFATACVVADRLGRTLIEADLRGLAARPVAQPVTLGELAG"
     gene            7733..8947
                     /locus_tag="EV186_RS35090"
                     /old_locus_tag="EV186_10933"
     CDS             7733..8947
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016310.4"
                     /locus_tag="EV186_RS35090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_10933"
                     /product="aconitase X catalytic domain-containing protein"
                     /protein_id="WP_133853841.1"
                     /transl_table=11
                     /translation="MTTLTADEQAMLAGDAGPAVAFAMRIVHRLAEGLGAPRLQEITAA
                     HVDGCLYNGQVNLDFATRLVDLGARVAVPTTLNVGSLDLLHPEIHRGLARDTDTTTNAR
                     ALMAAYRTMGCAPTWTCAPYQLARRPEFGEHVAFAESNAIAFVNSVLGARTDRYGDFID
                     ICAAITARVPYAGLHRDEARRATVVLDCRELPPELFDDTSGWAVLGYLTGSRTTGVPAL
                     TGLTAVPTEDDLKAFAATAASAGGVALFHIAGVTPEATEVRGLPVITVSPTDFGGARRA
                     LTTVEDAPVDAVSVGTPHFSASEFAALAALVRGRSDPKVPFYVSTSRAVLDQAADDASA
                     CAAAGITLITDTCTYVSSIVDPKARVVMTNSGKWAWYAPVNLGVDVVFGTLAECVRTAY
                     EGQPR"
     gene            8944..9303
                     /locus_tag="EV186_RS35095"
                     /old_locus_tag="EV186_10934"
     CDS             8944..9303
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014091.4"
                     /locus_tag="EV186_RS35095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_10934"
                     /product="DUF126 domain-containing protein"
                     /protein_id="WP_133853842.1"
                     /transl_table=11
                     /translation="MKVLHPGRGTGEVAKLDAPLSFWGGTDLTGHIRDPHHPQHGMLLA
                     GRVVVMPASRGSSSSSSVLAEQLRLGTAPAAIVLTERDPIILLGAIVAEQLYAVSLPVL
                     LLDPDEPRPEGVVTI"
     gene            9300..10178
                     /locus_tag="EV186_RS35100"
                     /old_locus_tag="EV186_10935"
     CDS             9300..10178
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1158: ornithine cyclodeaminase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014476.4"
                     /locus_tag="EV186_RS35100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_10935"
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="WP_133853843.1"
                     /transl_table=11
                     /translation="MILTANEVTAALPVLDAITALRSALEAGLDPEAGPPRTTAPLSAG
                     HLLVMPAEWGRHAGVKVVSVAPGNVDLPRIQGHYLLLDAKTLAPLRILDGIALTAIRTA
                     AVSALAVDALAPPGAARLVVFGAGPQAYRHVTALHAIRPVSEVIVVGRDPDRRQALVSW
                     CKEQGLAARNGAPDDVADADLVVCATTARTPLFDGSALPAQAVVVAVGSHEPDAAELDR
                     ATMTRGPVVVEARSAALREAGDVIQAGLGEDDLVDLATLVRDGCPDATVFKSVGMAWED
                     LVLAAHVHESA"
     gene            complement(10253..12640)
                     /locus_tag="EV186_RS35105"
                     /old_locus_tag="EV186_10936"
     CDS             complement(10253..12640)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020630259.1"
                     /locus_tag="EV186_RS35105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_10936"
                     /product="glycosyl hydrolase family 65 protein"
                     /protein_id="WP_133853844.1"
                     /transl_table=11
                     /translation="MTQGPLGYQIHPWELRWRGLSISQLERTESTFALSNGHIGIRGTL
                     EEGEPVGLPGTYLNGFYENHELPYAEAGYGYPESGQTVVNVTDGKIIRLLIEDEPLDMR
                     YGTARHHERVLDFRAGTLSRVTEWESPTGRVVRLKSTRLVSFTQRAIAAIRYEVEPIDG
                     QSMQVVAQSDLLANEPIEADRSGDPRVAAALQAPLVGQFAQAEGYRAVLVHQTRNSGLR
                     VAAAMDHEIDVQDGLRTRVHAEEDLGRLTAAAEVAADGKLVITKYLAYGWSAQRSAPAL
                     RSQVEAALAGAHQTGWDALLAEQREYLDNFWASADVEIEGDPELQQALRFALFHVLQAG
                     ARGETRAIAGKGLTGPGYDGHAFWDTETFVLPLLTYTVPDSARDALRWRHATLPLARER
                     AIQLGQAGAAFPWRSINGAECSAYWPAGTAAFHVSADIADAVARYYNATLDHDFDAECG
                     TEILVETARLWNSLGHHDQHGGFRIDGVTGPDEYSAIVDNNVYTNLMAQRNLREAADAC
                     DRNPDRAKALDVTADEVASWRSAADKMLIPYDDDLGVHPQAEGFTEHLDWDFAGTPEEK
                     YPLLLHFPYFDIYRKQVVKQADLVLAMFLRGDAFTPEQKLRNFDYYEARTVRDSSLSAC
                     TQAVLAAEVGHLDLAYDYLAEAALTDLHDLHNNVRNGLHMASLAGAWSSAVSGFGGMRD
                     YGGTISFAPRLPAALSGMTFRMVYRGTHFKVSVSRTEATYELLSGAELETTHHGEKLTI
                     SEKPVSLAIPELEDRTPPRQPPGREPARRVPLDGNTEANTPR"
ORIGIN
        1 gatgtccgcg gccgcgaccc cgcgccgggt gagttccgcg acggtcggga tctcgatcag
       61 cgcgcgcagc gcggtgaggt cgtccagttc cttgtcggac agttcggtga cgcggaaacc
      121 cttgttgcgc atggtttcca cgagtccttc gcggaccagg tcgagcatgg cctcgcggac
      181 cggggtcgcc gagacaccga actgttcggc caggctcggc gccgagtaca ccacgcccgg
      241 gcgcagctcc ccggagatca ccgcgccccg cagtgtctcg accagttcct cgcgcaggtt
      301 gcgccgggca cgcaacgacg gcaggtgcgg ccggtcttcc acagtcatgc gatcttcctc
      361 cgagcgtcac cgtacgtcac agctcgaagc cttcggggaa gggatcgctg gggtcgagga
      421 agtgttgtcc gatgccggtg acccacgcac tgccggtgat ggtcggcgtg acggtggtca
      481 ggtcgccgag cgtgccctgc tcgatgagcc gcccggtgaa gtgcgtgccc agcagcgact
      541 cgttgtcgaa gtcctcgtgc aggccgagtt cgccgcgggc gtggagttgc gccatgcgcg
      601 cgctggtgcc ggtgccgcag ggggagcggt cgaaccagcc ggggtggatc accatggcgt
      661 ggcgcgagtg cttcgccgtg gagccgggcg cggccaggta cacgtggtgg cagccggtga
      721 cctccgggtg ggcggggtgc acgggcttgg cctgctcgtt gatcgcctcc atgatggaca
      781 tcccggcgtc gagcaggcgc tgcttcccgg tccgctcgaa cgggatcccg agcttgtcca
      841 gttcgacgat cgcgtagaag ttgccgccga aggccatgtc gtagggcacg tcgccccacg
      901 gctcgacccg cacggtctgg tccagcgcca gcgcgaacga cggcacgttg gccagggtga
      961 ccgccttcgc cgcgccgtcc tccacccgca cggacgcggt caccaacccg gcgggggtgt
     1021 ccaggcggat ggtggtgacg ggctcggtca ccgcgaccat gccggtctcg accaggacgg
     1081 tcgccacgcc gatcgtgccg tgcccgcaca tgggcaggca cccggacacc tcgatgaaca
     1141 gcaccccgta gtcggcgtcg gggcgggtcg gcggctgcag gatcgccccg ctcatcgccg
     1201 ggtggccgtg cggttcgttc atcaggaacc gccgcaggtg gtcgaggttg gccatgaagt
     1261 agcggcgctt gtcgaacatg gtcgcgcccg gcacggtgcc gatgccgccg gtgaccacgc
     1321 gggtcggcat gccctcggtg tgcgagtcga ccacgtggat gacccgggaa ctacgcatca
     1381 ggacagcccc tccgccaagg ccttctccgt cgcctgccgc acgatcgcct cgtgctcgtc
     1441 ggtgagcggg acgcggggcg ggcgcgcagg accaccgtag cggccgacga tgtccatgct
     1501 gagcttgatg gcctgcacga actccgtctg ggagtcccag cgcagcaacg ggtgcaacgt
     1561 gcggtagagc ggcaacgcgg tcgccaggtc accgtcacga gcggccttcc acagccgcac
     1621 gcacgcgtcg gggaacgcgt tcggatagcc cgacacccag cccggcgacc cggcgatggc
     1681 cagttccagg gccacgtcgt cgctgccggc gagcacgtcc aggccgggcg ccgcctcggt
     1741 gatccggtag aggcgccgca cgtcgccgga gaactccttc accgcgacga tcaggccctc
     1801 gccgtgcagt tcggccagca ggtcgggcac gaggtcgacc ttggtgtcga acgggttgtt
     1861 gtaggccacg accggcagcc cggccttcgc gacctcgcgg tagtgcccga tcacggcgcg
     1921 gcggtcggcg cggtaggcgt tgggcggcaa caacatcacc accggtgccc ccgcttcggc
     1981 ggcctgttcg gcccaccggc gagcctcggc cgcgccgtag gcggcgacgc cgggcatgac
     2041 cgtgaagccg gcgggcgccg cttcgatcgc ggtggtgacc acgcgggcgc gttcgtcggg
     2101 ggtgagggtc tggtactcgc cgagcgagcc gttggggacg acgccgtcgc agccgttcgc
     2161 ggccagccac cgcacgtgct cggcgtagcc gtcgaagtcg gccgccaggt catcagttcg
     2221 gtcgtcactg cgcaggggga gcgcggtggc gacaagaaca ccgtgccaag cgggggtcgt
     2281 cattgaaatc ctccagaacg tcagggcgag tgcaatatta catggcattg gattgactgg
     2341 cagcgttgtg gtgtgtgaca ttgcactgca tggacgatgt cgctgaggtc agaggaacca
     2401 ccttctcctc ggccgagctt gccgcccggc tcgaccggtt accggtgtcg cgtttccact
     2461 accggctgct cgccgcgggc ggcctcgggt acaccttcga cgcgatggac ggcgcgatcg
     2521 tcgcgttcat catgccgccc gtcaccaagc agtggcacct gtcctcgctg gaaaccggcg
     2581 tgctgggcag cagcctgctg atcggattcc tgttcggcgc gttcttcgcc ggcgtgctcg
     2641 gcgaccgcat cggccgcaag aaggtcatgg tcagcgcgct gggcctgtac tgcgtcgcca
     2701 gcgtcgtggc cgcgttcgcg cccacgttct gggtgctgtt cgtggcccgg gtgatcgccg
     2761 gcgtcggcac cggcgcggag agcgcgatca tcgcgccata cctctcggag ttcgtgccga
     2821 cccgggtgcg cgggcgctac atcggctcgc tcgccgggtt cttcgccttc gggttcgtct
     2881 tcgcgagcct gctcggctac ttcatcgtgc ggtcgagccc cgacggctgg cgctgggtgc
     2941 agctgatcac cgccgtgccg atcgtcatgc tgctgtggtg gcggcgctcg ctgcccgaat
     3001 caccgcgtta cctgcacgtc caagggcgta cggcggaagc cgagaagatc gtgcgcgacg
     3061 tcgaggactc ggtgcgcgcc tcgaccgaca agccgctgcc gccggcgagc tccgtgccgg
     3121 ccgagaccga ggcgccggtg ccgcacgggc gcatcctgga caacctcaag gcgctgttcc
     3181 aaggcgggct gcggcgcacc acgttcacca cctgggtcta ctggttcgtc gcgatcttca
     3241 cctactacgg cttcttcacc tggatcccgt cgctgctggt caaccgcggc ttcgacatct
     3301 ccaagagctt cgcgttctcg atcctgatct acctggcgca aatccctggc tactactcgg
     3361 cggcgttcat cagcgaacgg ctggaacgca agtggacgat cgtgctctac ctctccggcg
     3421 gcgcggtcgc cgcctgggcg ctggccaacg ccgggtccag caccgagatc ctggtgtggg
     3481 gcatggtcct gtcgttcttc atgaacggca acgccgcgct cgagtacacc tacacctccg
     3541 agatctaccc gacggccatc aggaccaccg gcctcggcgt cgcttccgcg ctcggccggg
     3601 tcggcggggt gatcgcgccg ctgctgatcg ggttctccta ctcgagcgtc ggtttcggtg
     3661 gcgtcttcgc catgttgctg gtgttgttgg tgctgggcgc cgttgtggtc gcggtcttcg
     3721 gccagcgcac caacggccgg tcgctggaac agatcggccg ggacacgatc ggtgtggaga
     3781 ggagcacgcg tggctgacct ggttctccgg cacgtcgacg tcgtccaccc cgcgaccgcg
     3841 cgggtcgagc gcgaccggcg catcaccttg cgcgacggac ggatcgccgc gctcgaagcg
     3901 gacgacaccg ccggcctcga cgacgccgaa ttcgacggga ccgggctgtt cgcgctgccc
     3961 ggcctgatcg actgccacgt gcacgtcaac gcgatgaccg cggacctcgg gtccatcgtg
     4021 gacgaatcac cggcctacgt ggcggcgcgc gcgtcgcaga tcctgcgcgg gatgctcgag
     4081 cgcgggttca ccaccgtccg cgacgtcggt ggcgcggact tcgggctggc cgccgcggtc
     4141 gacgaaggga tcttcgccgg gccacggatc ttcttctgcg gcaaggcgtt gtcgcagacc
     4201 ggcggccacg gcgacggccg cccgcgcggc cgtgacatgc acgaccccgc ctacacccgg
     4261 cccgtgctcg gccgcatcgc cgacggcgtg gcgggggtgc gcgccgcggc acgcgacgag
     4321 atccgccgcg gcgcgcacca cctgaaggtc atgatctccg gcgggtgcgc cagcccgacc
     4381 gaccgcatcg actcgctgca gttctccgac gaagaactac gcgccatcgt cgacgaggcc
     4441 gcgcgcgccg gcctctactg cgccgggcac gcctacaccg ccgccgcggt caaccgcggc
     4501 ctggcgctgg gattccgcag catcgagcac ggcaacctgc tcgacgagac ctccatcgag
     4561 ctgttcctgg cccacgacgc gttctacgtg ccgacgctga tcacctacgt cgcgcaggtc
     4621 gaggccggcg ccgagctgga catcgccgcc gaccagctgg ccaaggtcga ccaggtcctc
     4681 gacggcggcc tgcgtgcact ggaactcgcc gaccgggccg gggtgaagat cgcgttcggc
     4741 accgacctgc tcggcgccat gcaccggcgc cagtgcgacg agttccggct gcgggccaag
     4801 gtgcagcgcc ccgaagcggt actgcgtggc gccaccacca tcgcggcgga actgttgcgc
     4861 cgcgacgacc tcggcgtctt cgcgcccggc gcggtcggcg acgtcgtgct cgcgcgcggc
     4921 aacccgctcg ccgacgtcga gctcctcgcc gacccgggcc gcgccatcgc cgccgtggtc
     4981 aaggacgggc ggctggtggc gtgacccgct ccgacgtgtc cgacgtgatc gtcatcggcg
     5041 ccgggatggt cggggcgatg accgcctacc actgcgccgc cgccgggttg cgggtcacgg
     5101 tgctcgaacg cgacgcggtc gccggcggca ccacgtccgc gtgcgagggc aacatcctgg
     5161 tgtcggacaa ggaacccggg cctgagctgg atctggcgtt gctgtccatc cggcggtggc
     5221 aggagctcgc cgatgagctg ggggcggaca gcctggagta ccaggccaag ggtggtgtcg
     5281 tggtcgccat gtccgacgac accggcgccg ggctcaccgc cttcaccgcg tcgcagcgcg
     5341 ccgcgggcat cgacgcccag gacgtctcca gcgcacaact gcgggagcgg gaaccgaacc
     5401 tgtcgccgga cgcgcgctcc ggcgcgtact acccgcagga cgcgcaggtg cagcccatgc
     5461 tcgccaccgc gcggctgctg cgtgcggtgc gggacctggg cgggaccgtg cgcaccggca
     5521 ccgaggtcac cgggttcgtc gagcgcggcg tggcgaccag cgccgggatc gtgcacgccg
     5581 agcacgtcgt caacgccgcg gggacgtggg ccgggcaggt gtccgagctc gccggcgccc
     5641 ccgtgccggt gttgccgcgc aagggattca tcctcgtcac cgagccgctg ccccggacga
     5701 tccggcacaa ggtctacacc gccgagtacg tcgccaacgt ggccagcagc gacgccgggc
     5761 tcgagacctc cgtcgtcgtg gagggcacca aggccggcac ggtgctgatc ggcgccagcc
     5821 gtgaacgcgt cgggttcgac cggtcgatgt cgctgccggt cgtgcgcaag ctggccgcgc
     5881 aggccatcga ggtcttcccg ttcctcgccg acgtggcctt gctgcgcagc tacctggggt
     5941 tccggcccta ctgcccggac cacctgccgg tgctcggtcc cgacccacgc gtgccgggac
     6001 tggtgcacgc ctgcggccac gagggggcgg gcatcgggct cgccgccggc accgggcacc
     6061 tcatcgcgca ggtgctcacc ggcaaagaac cggacctgga cctgaccccg ttccggccgc
     6121 accgattcga ggaggccccg gcgtgaggtt caccttcgac ggcaaggcga tccccgccga
     6181 acccgggcag tccatcggcg ccgcgttgat cgccgccggg caccggtcgt ggcggcgcac
     6241 ccgcatcgac gccgcgcccc gtgggatctt ctgcggcatc ggcatctgcc acgactgcct
     6301 ggtcaccgtg gacggcgccg ccaaccgcag ggcctgcctc gtcgaagccg ccgaggacat
     6361 gcgggtcacc acgcaagaag gagcgggccg tgccgaactc gagtgctgag cgcaacgagt
     6421 acgacgtggc ggtgatcggc gccggccccg cgggacttgc cgccgcggct gccgcggccg
     6481 acaccggcgt gtcagtagcg ttggtggatt caggtccacg cccgggtggc cagtactggc
     6541 gccaccgcac cggcgacgac ggaacacacc accacgactg ggccgagttc acccggctgc
     6601 gggcccggat acgcgaggtc gaccacctcg ccgagcacgc ggtctggcac atcgagcccg
     6661 gcttcaccgt gcacgccacc ggccgtgacc ctgttcgggc gcgacggctg gtgctcgcgc
     6721 ccggcgccca cgaccggcaa ctgccgttcc ccggctggac cctgcccggc gtctacaccg
     6781 cgggcggcgt gcaggcgctg ctcaaggggc acggtgtgct cgcgggaaag cggatcgtcg
     6841 tggccgggac cgggccgttc ctgctggccg tggctgccgg actgctcgac gcgggcgccg
     6901 gcgtggcggg ggtcttcgag gccggaacgc ccgccgggtt cgcacgccac ccgctggccg
     6961 tggccggtgc gctgggcaag ctgggcgaag gcgcgggcta cctgcgcgtg gtgggcaggc
     7021 gataccggac ccggaccatg gtgatcgccg cccacggcac cggcgagttg agcggcgtga
     7081 ccgtcgcgaa ggtcgacgcc aactggcagg tcgtgcccgg caccgaacgc gacgtggcct
     7141 gcgacgcgct cgccgtcggc tacgggttca cgccgcagct ggaactgccg ctgcagctgg
     7201 gttgtgcgac ccggctcgac gccgacggca gcctcgtcgc caccgccgac gaccgtcaga
     7261 tgtccactgt ggagggtgtg ttcctcgccg gagaggtgtg cggggtcggc gggtccgcgc
     7321 tcgcggtcac cgaagggttg atcgccgggc ggcacgccgc cggggtcagc gccggatcgc
     7381 ggctcctgcg ccggcgccgc gcgcagcgcc gctttgccgg ggccctgcac caggcgttcc
     7441 cgctgcgccg tggctggctg gatcgcgtcg gcgcggacac cgtggtgtgc cggtgcgagg
     7501 aagtgcgcca ccgcgcggtc acggccgccg tcgacgacct cggcgccacc gacccgcgga
     7561 cggtgaaact gctcgcccgg cccggaatgg ggctgtgcca aggccgcgtg tgcgggttcg
     7621 ccacggcgtg cgtggtcgcc gaccggctcg gccgcaccct catcgaagcc gacctgcggg
     7681 gcctggccgc ccggccggtc gcgcagccgg tgacgctggg cgagctcgcc ggatgaccac
     7741 gctcaccgcc gacgagcagg ccatgctggc cggggacgcc ggccccgcgg tcgcgttcgc
     7801 catgcggatc gtgcaccggc tcgccgaggg cctcggcgcg ccgaggctgc aggagatcac
     7861 cgccgcccac gtcgacggat gcctctacaa cgggcaggtg aacctggact tcgcgacccg
     7921 actggtcgac ctcggcgccc gggtcgccgt gcccaccacg ctcaacgtcg gctcactcga
     7981 cctgctgcac ccggaaatcc atcggggtct cgcccgcgac accgacacca ccaccaacgc
     8041 ccgcgcgttg atggccgcct accggaccat gggctgcgcg ccaacctgga cgtgcgcgcc
     8101 ctaccaactg gccaggcggc cggagttcgg cgagcacgtg gccttcgcgg agtccaacgc
     8161 gatcgcgttc gtcaactcgg tgctgggcgc gcgcaccgac cgctacggcg acttcatcga
     8221 catctgcgcc gcgatcaccg cccgcgtccc ctacgccggg ctgcaccgcg acgaggcccg
     8281 gcgcgccacc gtggtcctcg actgccgcga gctgccgccg gagttgttcg acgacacgtc
     8341 cggctgggcg gtgctcggct acctcaccgg ctcgcgcacc accggggtgc cggcgctgac
     8401 cggactgacc gcggtgccca ccgaggacga cctcaaggcg ttcgccgcga cggcggcctc
     8461 ggccggcggg gtcgcgttgt tccacatcgc cggcgtgacc cccgaagcca ccgaggttcg
     8521 tggcctcccg gtgatcacgg tgtcgcccac cgacttcggt ggtgcgcggc gggccctgac
     8581 caccgtcgag gacgcgcccg tggacgccgt cagcgtcggc acaccgcatt tctccgcgtc
     8641 ggaattcgcc gcgctggccg cgctggtgcg cggccgctct gacccgaagg tgccgttcta
     8701 cgtgtcgacg agccgggccg tgctcgacca ggccgccgac gacgcctcgg cctgcgccgc
     8761 cgcggggatc accctgatca ccgacacctg cacctatgtg tcgtccattg tggacccgaa
     8821 ggcgcgggtg gtgatgacca actccggcaa gtgggcgtgg tacgcgccgg tgaacctcgg
     8881 cgtggacgtc gtgttcggca cgctggcgga gtgcgtgcgc accgcctacg aagggcagcc
     8941 gcgatgaagg tgctgcaccc cggccggggg accggcgaag tcgccaagct cgacgcgccg
     9001 ctgtcgttct ggggcggcac cgacctcacc gggcacatcc gcgacccgca ccacccgcaa
     9061 cacggcatgc tgctcgccgg gcgcgtggtg gtgatgccgg ccagccgcgg ctcgagttcg
     9121 tcgtcctcgg tgctcgccga gcaactgcgc ctgggcaccg cgcccgccgc gatcgtcctg
     9181 accgagcgcg acccgatcat cctgctcggc gccatcgtgg ccgagcagct ctacgccgtg
     9241 tcgctgccgg tcctgctgct cgacccggac gagccgcgac cggagggtgt ggtgaccata
     9301 tgatcttgac cgccaacgag gtcaccgccg cgctgccggt gctcgacgcg atcaccgccc
     9361 tgcggtccgc gctggaagcg ggcctcgacc cggaagccgg accaccccgc acgaccgcgc
     9421 cgctgtcggc cgggcacctg ctggtgatgc ccgccgagtg gggccgccac gccggggtca
     9481 aggtcgtctc cgtcgccccc ggcaacgtgg acctgccccg catccaaggc cactacctgc
     9541 tgctggacgc gaaaaccctg gcgccactgc gcatcctcga cggcatcgcg ctcaccgcga
     9601 tccgcaccgc ggccgtgtcc gcgctcgccg tggacgccct ggccccaccc ggcgcggcgc
     9661 ggctcgtggt gttcggcgcg ggcccgcagg cctaccggca cgtcaccgcg ctgcacgcga
     9721 tccgcccggt gagcgaggtg atcgtcgtgg gccgcgaccc cgaccggcgg caggcgctcg
     9781 tgtcgtggtg caaggaacag ggcctcgccg cgcgcaacgg cgcaccggac gacgtcgcgg
     9841 acgccgacct cgtcgtgtgc gcgaccaccg cccggacccc gctcttcgac ggctccgcgc
     9901 tgcccgcgca agccgtcgtg gtcgccgtcg gctcccacga acccgacgcc gccgaactcg
     9961 accgcgccac gatgaccagg ggaccggtcg tcgtggaggc acgctcggcc gccctgcgcg
    10021 aagcgggcga cgtcatccag gccggcctcg gcgaagacga cctggtggac ctcgcgaccc
    10081 tcgtgcgcga cggctgcccg gacgcgaccg tgttcaagag cgtgggcatg gcgtgggagg
    10141 acctggtgct cgccgcccac gtccacgaat cagcctgaca aacgaagggc ctcgctctcc
    10201 ccgaacggtc gaggagagcg aggccttggc acgaaacgcg atcaggtcac cctcatcgag
    10261 gggtgttggc ctccgtgttg ccgtccaacg gaacccggcg cgccggttcg cggcccgggg
    10321 gctgccgcgg cggggtccgg tcctcgagct ccgggatggc cagcgacacc ggcttctcgc
    10381 tgatcgtcag cttctcgccg tggtgcgtgg tctccagctc cgcacccgac agcaactcgt
    10441 aggtcgcctc cgtgcgcgag accgagacct tgaagtgcgt gccccggtag accatccgga
    10501 acgtcatgcc cgacaacgcc gccggcagcc ggggcgcgaa cgagatcgtg ccgccgtagt
    10561 cgcgcatgcc gccgaacccg gacaccgccg aggaccaggc accggccagc gacgccatgt
    10621 gcaggccgtt gcggacgttg ttgtgcaggt cgtgcaggtc ggtgagggcc gcctcggcga
    10681 ggtagtcgta cgccaggtcc aggtgcccga cctccgcggc cagcaccgcc tgcgtgcacg
    10741 ccgagagcga cgagtcccgc acggtgcggg cctcgtagta gtcgaagttg cgcagcttct
    10801 gctccggggt gaacgcgtcc ccgcgcagga acatcgccag caccaggtcg gcctgcttga
    10861 ccacctgctt gcggtagatg tcgaagtacg ggaagtgcag cagcagcggg tacttctcct
    10921 ccggggtgcc ggcgaagtcc cagtccaggt gctcggtgaa gccctccgcc tgcgggtgca
    10981 ccccgaggtc gtcgtcgtag gggatcagca tcttgtccgc cgccgaacgc caggacgcga
    11041 cctcgtccgc ggtgacgtcc aacgccttcg cgcggtccgg gttgcggtcg cacgcgtcgg
    11101 ccgcctcccg caggttccgt tgcgccatca ggttcgtgta gacgttgttg tccacaatgg
    11161 ccgaatactc gtcgggcccg gtgaccccgt cgatgcggaa cccgccgtgc tggtcgtggt
    11221 ggcccaggga gttccacagc cgcgcggtct ccaccaggat ctccgtgccg cactcggcgt
    11281 cgaagtcgtg gtccagcgtc gcgttgtagt accgcgccac cgcgtcggcg atgtcggcgg
    11341 acacgtggaa cgccgccgtg cccgccggcc agtacgccga gcactccgcg ccgttgatcg
    11401 agcgccacgg gaacgcggcc ccggcctgcc cgagctggat cgcccgctcc cgcgccagcg
    11461 gcaacgtcgc gtgccgccac cgcaacgcgt cccgcgcgga atcgggcacc gtgtaggtca
    11521 gcagcggcaa cacgaacgtc tcggtatccc agaaggcgtg cccgtcgtag ccggggccgg
    11581 tcaggccctt gcccgcgatc gcgcgcgtct caccgcgggc cccggcctgc agcacgtgga
    11641 acagcgcgaa ccgcagcgcc tgctgcaact ccgggtcgcc ctcgatctcc acgtccgccg
    11701 acgcccagaa gttgtccagg tactcccgct gctcggccag caacgcgtcc cacccggtct
    11761 ggtgcgcgcc ggcgagcgcg gcctccacct gcgagcgcaa cgccggcgcc gaacgctgcg
    11821 ccgaccaccc gtaggccagg tacttggtga tgacgagctt gccgtcggcg gcgacctcgg
    11881 ccgcggcggt cagccggccc aggtcctcct cggcgtgcac gcgggtgcgc agcccgtcct
    11941 gcacgtcgat ctcgtggtcc atcgccgcgg ccacccgaag acccgagttg cgggtctggt
    12001 gcaccagcac cgcccggtag ccctcggcct gcgcgaactg cccgaccagc ggcgcctgca
    12061 acgcggccgc cacccggggg tcaccggagc ggtcggcctc gatcggctcg ttggccagca
    12121 ggtcggactg ggcgaccacc tgcatcgact gcccgtcgat cggctcgacc tcgtagcgga
    12181 tcgcggcgat cgcgcgctgg gtgaacgaca ccagccgcgt cgacttgagc cgcaccacgc
    12241 gcccggtcgg cgactcccac tcggtgaccc gcgacagcgt gcccgcccgg aagtcgagca
    12301 cccgctcgtg gtggcgggcc gtgccgtaac gcatgtccag cggctcgtcc tcgatcagca
    12361 gccggatgat cttgccgtcg gtgacgttca cgaccgtctg cccggactcc gggtagccgt
    12421 agcccgcctc ggcgtagggc agctcgtggt tttcgtagaa gccgttgagg taggtgccgg
    12481 gcagcccgac cggctcaccc tcctcgagcg tgccgcggat gccgatgtgc ccgttggaca
    12541 gggcgaacgt cgactcggtg cgctcgagct ggctgatgga caagccgcgc cagcgcagct
    12601 cccacgggtg gatctggtag cccaggggtc cctgcgtcac gatcggtcct ccagcagctc
    12661 ggcgaggtcg tcgaccacta catcggcgcc gtgcgcccgg agttgctcgg cttggtcggc
    12721 acgattcaca ccgacc
//
