LOCUS       NZ_SNXZ01000008        22496 bp    DNA     linear   CON 20-APR-2024
DEFINITION  Labedaea rhizosphaerae strain DSM 45361 Ga0310470_108, whole genome
            shotgun sequence.
ACCESSION   NZ_SNXZ01000008
VERSION     NZ_SNXZ01000008.1
KEYWORDS    WGS; RefSeq.
SOURCE      Labedaea rhizosphaerae
  ORGANISM  Labedaea rhizosphaerae
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Labedaea.
REFERENCE   1  (bases 1 to 468468)
  AUTHORS   Goeker,M.
  TITLE     Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing
            the most valuable type-strain genomes for metagenomic binning,
            comparative biology and taxonomic classification
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 468468)
  AUTHORS   Goeker,M., Huntemann,M., Clum,A., Pillay,M., Palaniappan,K.,
            Varghese,N., Mikhailova,N., Stamatis,D., Reddy,T., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-MAR-2019) Prokaryotic Super Group, DOE Joint Genome
            Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.12.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 180.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004362825.1-RS_2024_04_19
            Annotation Date                   :: 04/19/2024 13:11:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,820
            CDSs (total)                      :: 7,753
            Genes (coding)                    :: 7,690
            CDSs (with protein)               :: 7,690
            Genes (RNA)                       :: 67
            rRNAs                             :: 3, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2 (5S)
            tRNAs                             :: 59
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 11 of 63
            Pseudo Genes (incomplete)         :: 55 of 63
            Pseudo Genes (internal stop)      :: 3 of 63
            Pseudo Genes (multiple problems)  :: 6 of 63
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 17:41:24
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 225065
            Orig. end                         :: 247561
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            SNXZ01000008.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22496
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iv"
                     /region_number="2"
                     /rules="(cds(LANC_like and Pkinase) and not micKC)"
                     /tool="antismash"
     cand_cluster    1..22496
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="single"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22496
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12496](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12496)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
     misc_feature    126..139
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.11"
                     /tool="antismash"
     gene            329..1036
                     /locus_tag="EV186_RS33735"
                     /old_locus_tag="EV186_108208"
     CDS             329..1036
                     /NRPS_PKS="Domain: PKS_KR (4-158). E-value: 1.2e-22. Score:
                     72.6. Matches aSDomain:
                     nrpspksdomains_EV186_RS33735_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017988127.1"
                     /locus_tag="EV186_RS33735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_108208"
                     /product="beta-ketoacyl-ACP reductase"
                     /protein_id="WP_133853554.1"
                     /sec_met_domain="adh_short (E-value: 4.5e-39, bitscore:
                     129.1, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGGRSVLVTGGNRGIGLAIARAFAEQGDKVAVTHRGSGAPEGLLG
                     VQCDVTDVDQIDAAFTEIEAAHGPVEVLVANAGITDDTLLMRMSDEQFTRVIEANLTGS
                     FRVVKRASRGMLRAKFGRIVFISSVVGLNGSPGQVNYAASKSGMIGMARSITRELGSRN
                     ITANVVAPGFVVTDMTNALSEDQRKAIIDQIPAKRYAEPEEVAGVVTFLASDAAAYING
                     AVVPVDGGLGMGH"
     CDS_motif       341..415
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EV186_RS33735_0001"
                     /evalue="2.80E-08"
                     /label="PKSI-KR_m1"
                     /locus_tag="EV186_RS33735"
                     /protein_end="29"
                     /protein_start="4"
                     /score="26.4"
                     /tool="antismash"
                     /translation="SVLVTGGNRGIGLAIARAFAEQGDK"
     aSDomain        341..802
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EV186_RS33735_PKS_KR.1"
                     /evalue="1.20E-22"
                     /label="EV186_RS33735_PKS_KR.1"
                     /locus_tag="EV186_RS33735"
                     /protein_end="158"
                     /protein_start="4"
                     /score="72.6"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="SVLVTGGNRGIGLAIARAFAEQGDKVAVTHRGSGAPEGLLGVQCD
                     VTDVDQIDAAFTEIEAAHGPVEVLVANAGITDDTLLMRMSDEQFTRVIEANLTGSFRVV
                     KRASRGMLRAKFGRIVFISSVVGLNGSPGQVNYAASKSGMIGMARSITRE"
     CDS_motif       698..757
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EV186_RS33735_0002"
                     /evalue="3.40E-07"
                     /label="PKSI-KR_m4"
                     /locus_tag="EV186_RS33735"
                     /protein_end="143"
                     /protein_start="123"
                     /score="22.8"
                     /tool="antismash"
                     /translation="VFISSVVGLNGSPGQVNYAA"
     gene            1066..1836
                     /gene="fabI"
                     /locus_tag="EV186_RS33740"
                     /old_locus_tag="EV186_108209"
     CDS             1066..1836
                     /EC_number="1.3.1.9"
                     /GO_function="GO:0004318 - enoyl-[acyl-carrier-protein]
                     reductase (NADH) activity [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="fabI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005451241.1"
                     /locus_tag="EV186_RS33740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_108209"
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="WP_133853555.1"
                     /sec_met_domain="adh_short_C2 (E-value: 2.4e-82, bitscore:
                     271.3, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGLLEGKRLLITGMITDASIAFHVAKTAQEQGAKVVLTGFPRMS
                     LVKLIAKRLPAEAPVLELDVTNDEHLDSLADRVREHVDGLDGVLHSIAFAPQTCLGAPF
                     MDAPAPDVANAVEVSAFSYKSLAKACLPLMTNGGSIVGMDFDARVAWPAYNWMGVAKAA
                     LESVNRYLARELGPQGIRVNLVSAGPLATMAAKSIPGFDELRDAWDGRAPLGWDVKDAT
                     PTAKTVCALLSDWLPATTGSMIMVDGGVHAMGQS"
     gene            1839..2885
                     /locus_tag="EV186_RS33745"
                     /old_locus_tag="EV186_108210"
     CDS             1839..2885
                     /EC_number="4.98.1.1"
                     /GO_function="GO:0004325 - ferrochelatase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006783 - heme biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015801016.1"
                     /locus_tag="EV186_RS33745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_108210"
                     /product="ferrochelatase"
                     /protein_id="WP_133853556.1"
                     /transl_table=11
                     /translation="MQVDALLWLSFGGPEGPEDVRPFLENVTRGRGVPPERLDEVEQHY
                     QHFGGVSPINALNCAAIEAVRAEFAAAGIDLPIYFGNRNWHPMAADTVAEMTAAGVKRA
                     LVFPTSAYGGYSACRQYDEDIVAARASVGADAPELVKLRHFFDHPLFIESFVDSVKAAA
                     ATLSTQDYRLVFTAHSVPLSADAAAGPPEEGGHRYSRQIAEAARLVAAGVGVADYDVVW
                     QSRSGPARIPWLEPDIVDHLDALHAKGIGAVVGCPIGFVSDHLEVVWDLDTEARERAGE
                     LGMEFARAATPGADRRFAQLVVELVREHLDGAPARKLSEFPVAGCTVNGAICAVGCCEP
                     AKRPARPA"
     gene            2942..4315
                     /locus_tag="EV186_RS39210"
     CDS             2942..4315
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EV186_RS39210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_166659456.1"
                     /transl_table=11
                     /translation="MTRLRGVVAVVCAVLLTASCGAVSTAGNQETDRQSQTLADAISYP
                     RQENAAAFARAALATTLGKTPSFSVLEATDLPHTSLSEPMARLVWRIHHDATHSGYGDE
                     PELDACYRVEFDYYGPSSGPTRVTCPAGATPITPPPLPGRDIPSTYAPALKSVLGKLPD
                     RPTEADVRAALTAGLPKPVVNPETGLANVPPQVFVEVRGVDVGVALFARTGVESKDCMM
                     GHRVGGTVAVWSLNQRELTTNGEPVHHSGRVEHRLADRCQVGDPARRQLVPDGQAQGEP
                     QVLELANVHFERCRLPSEGLRQVGCSHARARLDRCQSGPCPRAPGTRGVEPVQAGGDRR
                     DVVGGQVGRLGEHRARIRVGHGVDPHQVDRRRRIAAQVGPGGVGARVACGAGIGLGQRC
                     RVDPLDRGHADHARRRAVDAARAGLALPPPAQQHGDRAVADALLETALDQHAVVPLCS"
     misc_feature    2951..2953
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(4396..5178)
                     /locus_tag="EV186_RS33755"
                     /old_locus_tag="EV186_108212"
     CDS             complement(4396..5178)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020659415.1"
                     /locus_tag="EV186_RS33755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_108212"
                     /product="hypothetical protein"
                     /protein_id="WP_133853788.1"
                     /transl_table=11
                     /translation="MTTFAVWTSAWLSGNAAPDDVLDAMAHWAPMHEVVADDDGTATVL
                     DLPADGEPAATPAALLGALRRGGAESARLVLPVPGDVRGLGGRSAFSAAALRHGEAAVF
                     GGAALGVVTEEVAEGILRWTVFDLPEPPRAEHVPIGEAEHGLTQAVRDAAGALAELDVA
                     RDRPGVREEMAALLRLATRSPWPDGMPPRALRVLQRASEVGVMIALAAEDEPGGALSSS
                     AAIRRSEALRPVHDAVRTARSAAVDEAVRVLSDHAERR"
     misc_feature    complement(4891..4893)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(5227..5721)
                     /locus_tag="EV186_RS33760"
                     /old_locus_tag="EV186_108213"
     CDS             complement(5227..5721)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025675.4"
                     /locus_tag="EV186_RS33760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_108213"
                     /product="YcxB family protein"
                     /protein_id="WP_133853558.1"
                     /transl_table=11
                     /translation="MTQKDRVEFRWWPKPADWTDALRATLPVYRWAPWFAGVLAAGSVV
                     LLVVGQLVAGGFGLCAAVVVAAIPVVGVYSAFRANPVASSEVTAVADEHAMRMMTVDGT
                     AHTELRWPQVTGWQRTRRGYVLRTGASVGEMYPVPARAFGADGRDAFDALLREHVGTAE
                     D"
     gene            5791..7206
                     /locus_tag="EV186_RS33765"
                     /old_locus_tag="EV186_108214"
     CDS             5791..7206
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008134 - transcription factor binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020423223.1"
                     /locus_tag="EV186_RS33765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_108214"
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="WP_133853559.1"
                     /transl_table=11
                     /translation="MRSVVVVNEAPSNLPRTAGELRAAGYLPRGVKTEIKENLLAALRS
                     GASAWPGIVGFDTTVLPQLERALLAGHDVVLLGERGQGKTRLLRTLAGLLDEWTPVIEG
                     SELGEHPLEPITPASIRRAAELGDDLPVAWRHRSERYAEKLATPDTSVGDLIGDVDPVK
                     VAQGRSLGDPETIHFGLVPRAHRGIVAVNELPDLAERIQVALLNVMEERDIQVRGYTLR
                     LPLDVLLVATANPEDYTNRGRIITPLKDRFGAEIRTHYPLSLKGEIALVRQEAELSAEV
                     GEVLLEIIARFVRNLRESAAIDQRSGVSARFAVAAAETVAAAALRRSALTGEDEPVARP
                     IDLDSVPAVLRGKLEFESGEEGRETEHLTHLLRKATAETARAKFGGLDLRPLTDAVADG
                     HLVATGEKVPAIEVLQALPELPVLHEVAARVGVKPDDNPGRIAAAVELALELLYLQRKV
                     AKDAEDGTAVYGP"
     gene            7203..9158
                     /locus_tag="EV186_RS39215"
                     /old_locus_tag="EV186_108215"
     CDS             7203..9158
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009154435.1"
                     /locus_tag="EV186_RS39215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_108215"
                     /product="VWA domain-containing protein"
                     /protein_id="WP_166659457.1"
                     /transl_table=11
                     /translation="MTAPDRYSYGPYHEGPDPLAPPVDLSAALEDIGRDVLEGSSPRSA
                     MEELLRRGVRGTQGLDDLTRRLWQRRAQLQRRNRLDGTMQRAKELLDKALEAERRTLFP
                     DPSDDARFREAQLDALPTGTAAQINELAQYDWQSDEAREAYQELQDMLGQQLMESRFQG
                     MKQALEQSTPEDVERIREMMTDLNDLLLSHLRGEDTKDKFDRFMAKHGEFFPENPRNVE
                     ELIDALAQRSAAAQRMMNSMSEEQRAELGELMGQAFGDPRLAQQVAELDANLRALRPGE
                     DWQGSGRFRGNNPMELGEGVQAMQDLAEMDALAEQLGQSYPGARLEDIDLDSLRRQLGD
                     EAAVDARRLSELERELRAQGLFERAPDGSLRLTPKALRKLGQTALRDVVTSLRSRKGER
                     DTARAGAAGEPTGSSRPWQFGDTEPWEVSRTVRNAVLRSVSTGSGAVDLDVSDVEVVET
                     EQRARAAVALCVDTSWSMVQDGRWVPMKRTALALHQLIKTRFRTDALQLITFGRHAMNV
                     DLAELVGLEGVWEQGTNLHHALLLAGRHLRKNSDAQPVVLVVTDGEPTAHLEPDGEAEF
                     HYPPLPRTLRSTMAQVDALAKLGASISVFMLGDDPRLAEFVDLVARRGGGRVIAPDLDG
                     LGAAVVGDYLRSRRAR"
     gene            9165..9521
                     /locus_tag="EV186_RS33775"
                     /old_locus_tag="EV186_108216"
     CDS             9165..9521
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003082494.1"
                     /locus_tag="EV186_RS33775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_108216"
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="WP_208115913.1"
                     /transl_table=11
                     /translation="MDRSERARAAVAAARAETIRLIEALGGRWQAIVDASALAADDDEH
                     DPEGATVAFERAQVGSTLVAAQAELAELDTAAARIADGTYWTCTACGGPIAQDRLEARP
                     MARTCIACARTADR"
     gene            complement(9522..9902)
                     /locus_tag="EV186_RS33780"
                     /old_locus_tag="EV186_108217"
     CDS             complement(9522..9902)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010693055.1"
                     /locus_tag="EV186_RS33780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_108217"
                     /product="VOC family protein"
                     /protein_id="WP_133853560.1"
                     /transl_table=11
                     /translation="MPRPVHFEIHAADPARAQAFYEHVFGWRFRRWGENPYWLIQTGEG
                     PGIDGGMVPRRGPRPAADAPVAAFPLTMDTADLDATLAAVLAAGGTVVVPRSALPGLGY
                     TAYCTDTEGNIFGLMQADESAA"
     gene            complement(10001..12496)
                     /gene="lanL"
                     /locus_tag="EV186_RS33785"
                     /old_locus_tag="EV186_108218"
     CDS             complement(10001..12496)
                     /codon_start=1
                     /gene="lanL"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF038150.1"
                     /locus_tag="EV186_RS33785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_108218"
                     /product="class IV lanthionine synthetase LanL"
                     /protein_id="WP_133853561.1"
                     /sec_met_domain="Pkinase (E-value: 1.7e-10, bitscore: 35.5,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.9e-21, bitscore:
                     71.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHAPPLTRCGPVRGSWDRLVARVLGDGWSLRRGATRVLALPDGTA
                     LRAQGWLLAVSATTTSAGMVLARTAEVLAARRCPFTFAATISAVRALNAQDADLAVAAR
                     FLTIYPNSDDDVAELARELDAATRGLPGPVITSARPVCAGSLVHYRYAAFVPLRRLADS
                     GRYEQVVHAPDGSAVPDRPELWLPPWSPDPIGAPSAPMPNPLGTRFVPRGAGDRFRALD
                     RSTGAEVVVTRGRAHVDETPAGDLRDRLRAEAAMLALLGPTGLVPDLVTVHERSGQTFL
                     ITSAVEGTPLADHVRTLSGEQRHDLAIQLTELLAQIHFEGVVLRDLSPATVVVEPGGTL
                     RLSRLAMAAPAGAEVTGAGPRGFAAPEQLASAAVPTPADPAADLFSLGAMLFFLAVGAE
                     PVLAKEYPERGARGRLRPWLDGAAVDNPLVRRYRPLILDLVADDPQDRCGLDAVAERLT
                     RRVVAPAPPAARPGEEAADELVRDGVGYLLAAMAGPGADRLWPGEANTDPTIVHCGSAG
                     VLNALVRAMPYLRDGLLFDAVQRAAWWTADRCAEEPTVLPGLHHGRSGVVWSLLEAAQA
                     VQDRRLRDRALELAGDIPVHGPDPGVHRGIAGAGLAMLHCWRACGDPALLGKAVRCAEH
                     LLATVDDTEPVWWLPDASVQTGFAEGTAGIATFLLDCWRATEDERYLAIARRAADFLCG
                     QAVHDHAGTGTFLVRAWAATGDPRHLETAQAIATPVRAEQWTRPPTVANGVAGGMDFLL
                     DLAEATGDPDPRDAAWHGLAALRARTTHRYGRTVVCDESGRTAMAGHDIGVAGVLSTVI
                     RLRHGGSRPWLPPVTPDEE"
     gene            12652..13083
                     /locus_tag="EV186_RS33790"
                     /old_locus_tag="EV186_108219"
     CDS             12652..13083
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013675949.1"
                     /locus_tag="EV186_RS33790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_108219"
                     /product="VOC family protein"
                     /protein_id="WP_133853562.1"
                     /transl_table=11
                     /translation="MAIKVQVTFDAHDAEALASFWQLALDYAEQQPPPGFATWQDFAAK
                     IGMPEEKWHAFGAAIDPSGAGPRLFFQQVPEGKVAKNRVHLDLNVSGGPNSGEEGWKRV
                     LAHSEKLVAAGASVQYESNEPNGRCLVMKDPEGNEFCIQ"
     gene            13092..13496
                     /locus_tag="EV186_RS33795"
                     /old_locus_tag="EV186_108220"
     CDS             13092..13496
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006239134.1"
                     /locus_tag="EV186_RS33795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_108220"
                     /product="VOC family protein"
                     /protein_id="WP_243754437.1"
                     /transl_table=11
                     /translation="MAFDCADPHAQARFWAQVFGTVVEDHHDLVEQLVAAGRMSAEERI
                     VLDRRSAFRDVAAVRDPSGVEPRLFFQRVPEGKSAKNRCHVDIHVDEADKPAEVERLMA
                     LGARHLETHADRGPTVYVMQDPEGNEFCLH"
     gene            complement(13498..14430)
                     /locus_tag="EV186_RS33800"
                     /old_locus_tag="EV186_108221"
     CDS             complement(13498..14430)
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020629726.1"
                     /locus_tag="EV186_RS33800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_108221"
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_133853564.1"
                     /transl_table=11
                     /translation="MTEADESVHTDPAAIAELTDAARASHLGAGASGAVEGYRARRTLR
                     LHVELRRQLRRRRTQLLYGFLVLLPFLLAVAFEVGSSNPNRRSGGFVDLATASAPNFVV
                     LTLFVSGTFLLPMIVALFFGDTIASEASWSSLKYLLAIPVPRHRLLAQKALASAVLSFA
                     ALVLLPLVAFLVGLVSYGAGEAVTPTGDAVDFPTALAAIGMSVVYISIQLIWVAGLAMF
                     LSVLIDAPLGAVGGAVLVSILSQILEQITALGSLRQYLPTHFAFSWSDLIATDIDWTNL
                     AKGTLSALIYGLVFGTLAFRRFTTKDITS"
     gene            complement(14427..17327)
                     /locus_tag="EV186_RS33805"
                     /old_locus_tag="EV186_108222"
     CDS             complement(14427..17327)
                     /NRPS_PKS="Domain: Abhydrolase_1 (72-178). E-value:
                     1.3e-11. Score: 36.5. Matches aSDomain:
                     nrpspksdomains_EV186_RS33805_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015104026.1"
                     /locus_tag="EV186_RS33805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_108222"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_208115914.1"
                     /sec_met_domain="PF00561 (E-value: 3.1e-09, bitscore: 31.6,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRIPRSVFRWTAFAVVAALIVITVVLVTRPSSTGQQVRTQEKVL
                     TLVDGPAGKRAPVAIDTTLYLPEKTPAPAVMIAHGFGGSKRSVDADAREFAAQGFVVLA
                     WSARGFGRSGGTIELNSPDYEVEDAKQLVSWLAKRPEVRLDGPGDPRVGVTGGSYGGAL
                     ALMLAGADKRVDALAPVITYNDLSQALLPNTGSTGAMPAGTPAAGPFGADGVFKRAWAG
                     IFFASGMGGGGDAGSSGPEAPEPGTVSGSSDAAAGGDAAAPAPAPSTGGDTAGGDQGGD
                     APPAGATGGPCGRFGLDVCKAYAEVATTGVPSAETVALLKSVSPVSVTSKITQPTLLVQ
                     GEQDTLFGLDQADANARQIAAAGGSVKVIWYAGGHDGGRPGPQLREEMRNWLAYQLDKR
                     GTDPGTGFEYAVQGALRAQGAPSVRVVRAPAYPGLTGAPVQRQAMAMSGAAQTVINPPG
                     ANPGSVSSLPGLSSVLAGAGGRLSGRTSIDLPGQSAIFSGPTLDEQLLIAGSATARLDV
                     SAMPGLPPSKTGAVLFAKLYDVGPDGTRILPGSAVSPVRVPPLPVNGDSVKVTVALPGI
                     VRPVESGHYLSLVVTTTDQSYATPLEPAAYRIALADDTIAVPVVPGTNVGGPAPVGPVI
                     GIIVVLGIGVLLVLAVALRRRRSGRPDPELTDVPLVIDGLTKRYPGGLVAVDDLSFRVD
                     RGQVLGLLGPNGAGKTTTLRMLMGLIHPTGGTIKVFGQEIRPGAPVLSRIGSFVEGAGF
                     LPHLSGADNLRLYWAATGRPAERAHVHEALEIAGLGKAVNRKVRTYSQGMRQRLAIAQA
                     MLGLPDLLVLDEPTNGLDPPQIHQMRSVLRAYAATGRTVLVSSHLLAEVEQTCDHVVVM
                     HRGRLVAAGPVDEIVSGGGEATFRVDRPDVAADVLRGISGVTGVAVDGSAVHAELDGTP
                     RSVAIGVLVSAGVAVEQAGPRRRLEDVFLQLVGEDS"
     aSDomain        complement(16794..17111)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EV186_RS33805_Abhydrolase_1.1"
                     /evalue="1.30E-11"
                     /label="EV186_RS33805_Abhydrolase_1.1"
                     /locus_tag="EV186_RS33805"
                     /protein_end="178"
                     /protein_start="72"
                     /score="36.5"
                     /tool="antismash"
                     /translation="PAVMIAHGFGGSKRSVDADAREFAAQGFVVLAWSARGFGRSGGTI
                     ELNSPDYEVEDAKQLVSWLAKRPEVRLDGPGDPRVGVTGGSYGGALALMLAGADKRVDA
                     LA"
     gene            17623..18678
                     /locus_tag="EV186_RS33810"
                     /old_locus_tag="EV186_108223"
     CDS             17623..18678
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005439761.1"
                     /locus_tag="EV186_RS33810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_108223"
                     /product="TerC family protein"
                     /protein_id="WP_133853566.1"
                     /transl_table=11
                     /translation="MIVPAWIWLATIVGLLILLAVDLVIVDRKPHEVTVGEAARWVVFY
                     IACAAVFGAALWAFAGKTPAIEFFSGYITEYSLSVDNLFVFVVIMGAFKVPVVHQHRVL
                     LVGILIALVMRGLFIAAGAAVIDRFSWVFWLFGAFLVATAYKMARSGLGGEEDEEYKEN
                     AAIRVIRKIVPVSKDYHGSKSFVRLSGRRLVTPMFVVMFAIGTTDLLFALDSIPAIFGL
                     TKEPFLVFAANAFALMGLRQLYFLLGGLLQKLVYLSIGLSAILGFIGVKLMLEALHDNT
                     LPFINGGQGVHVPTISITLSLSVIVGVLLITTVASLIKARRDPDSVRKTPGLPGGDDAD
                     ASEQRSAREAA"
     gene            18740..20695
                     /locus_tag="EV186_RS33815"
                     /old_locus_tag="EV186_108224"
     CDS             18740..20695
                     /EC_number="3.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005448930.1"
                     /locus_tag="EV186_RS33815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_108224"
                     /product="S9 family peptidase"
                     /protein_id="WP_133853567.1"
                     /sec_met_domain="PF00561 (E-value: 1.4e-06, bitscore: 22.9,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_S9 (E-value: 9.6e-50, bitscore:
                     163.8, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRPEDIELLAAPTEVTVHGDLTLVALSTPNLAVDGNRGGLHRVDL
                     TGGGSTPWTHGDRDSAPTISPDGQWVAFLRVSGPKGKERPQLHVMPTGGGEAREVTSLP
                     GGAGAPVWAPDSRRIAFCTRVPEPGRYGISLPDNDSEVIEAAAEAPRRITRLFYRLDNV
                     GFVDDQPLQLFVVDALADEPEAKQLTTGNAEPGDPAWSPDGTRVYVAARKDWGVDDTLI
                     TDLYAVPADGGEPELVASIEGDASLPVVLADGTVVLLGDHTPADEHGRPQAEARNAGVW
                     SVRPGAAPVRLTDEETVDVERGAGAPVLVPGGVLVAVRNRGAIELREVPVDGTVRTLSE
                     LPVLAGEQGQVRAFAAHNGRVVAVVSTPDSAGEVVVVDAGESRVLTDFSAPLKAAGLRP
                     VVEIKAAAPDGYPTHGWLVLPEGDGPHPVLLHVHGGPFMYHGWGFFDEAQVYAAAGYAV
                     VLANPRGSSGYGQAHGQAIVGALGTVDVDDVLSVLDAALERPECDETRVGVMGGSYGGW
                     MTGWLAAKHGDRFVAAWSERAVNAWDSFAGSSDIGWFFADGYCGYGAEARRAVSPLTYA
                     DDIHIPFAIVHSEHDWRCPIEQAQRMFVALKKNGVDTEMLIFPGEGHELTRSGRPKHRK
                     QRFDAVLEWWSRHLPV"
     misc_feature    18761..18763
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(20692..21558)
                     /locus_tag="EV186_RS33820"
                     /old_locus_tag="EV186_108225"
     CDS             complement(20692..21558)
                     /GO_process="GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099987.1"
                     /locus_tag="EV186_RS33820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_108225"
                     /product="patatin-like phospholipase family protein"
                     /protein_id="WP_243754438.1"
                     /transl_table=11
                     /translation="MLELPRPVGFVLGGGGSLGASQVGMLRALAEHGVTPDLVTGTSVG
                     SLNGAVLARAGEIPVERLSAIWTSMTRRAVFPGGPLAQAVTLRKSRTHLFTSVGLGALV
                     DEVLGSDTTFDDCAIPLGVVAMDVATTQAVLLREGPLKPAVLASAAIPGIYPPVELGDG
                     LYYDGGVVANVPMRQAVAMGAKSLVVLDCAFPSRLPAAPRTIAEVVFMVAMVAMRQQAV
                     LEAPAIAAELPVVYLPGPPLIRVSPLDFTHTAELLGEAYVAASAFLHDLRVSGPGLYQQ
                     AGATVND"
     gene            complement(21564..21974)
                     /locus_tag="EV186_RS33825"
                     /old_locus_tag="EV186_108226"
     CDS             complement(21564..21974)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009944929.1"
                     /locus_tag="EV186_RS33825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_108226"
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="WP_133853568.1"
                     /transl_table=11
                     /translation="MKILYTAVATATGREGKASTSDGKLEVTLAPPTEMGGSGEGTNPE
                     QLFATGYAACFASALGAVGRRQKVDTANASVTAEVGIGPDGKGGFGLAVKLKVTIPDVD
                     RETGEQLVEAAHQVCPYSNATRGNIDVDLELV"
     misc_feature    complement(21959..21973)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.18"
                     /tool="antismash"
ORIGIN
        1 cccctggccc gccggacgcc cgcatcccga cgcgctccca cccgggctac cactggctgt
       61 acgtcctgcg cggtgccctt cgcgtcctcc tcggtgatgc cgagtacgtc gtacgggcgg
      121 gcgagtcgtt cgagatcagc gacacgcgcc ttgctcacgg cttcggcaac gccgagcccg
      181 ccgccgtgga gttcctcagc atcctgggca acagcgagca gggcatcacc caccggcggc
      241 cgggctgatc ggtggcgtgc ctgtgcggtg gctgcggctg ggcggatagc ctcacggtgt
      301 cgtggatcgg ctaggtgagg gagctgtggt gggcggacgg tcggtgctgg tgaccggggg
      361 caaccggggg atcgggctgg cgatcgcgcg ggcgttcgcc gagcagggcg acaaggtcgc
      421 cgtcacccat cgggggtccg gggcgcccga gggtctgctg ggcgttcagt gcgacgtcac
      481 cgatgtcgac cagatcgacg ccgccttcac cgagatcgag gccgcgcacg gccccgttga
      541 ggtcctcgtg gccaacgcgg gcatcaccga cgacacgctg ctgatgcgga tgagcgacga
      601 gcagttcacc agggtgatcg aggccaacct gaccgggtcg ttccgggtgg tgaagcgcgc
      661 ttcccgcggg atgctgcggg ccaagttcgg gcggatcgtg ttcatctcgt cggtggtcgg
      721 gctcaacggc tcgcccggcc aggtgaacta cgcggccagc aagtccggga tgatcggcat
      781 ggcccgctcc atcacccgcg aactgggctc gcgcaacatc accgccaacg tggtcgcgcc
      841 cggcttcgtg gtcaccgaca tgaccaacgc gctcagcgaa gaccagcgca aggcgatcat
      901 cgaccagatc ccggccaagc ggtacgccga gcccgaggag gtcgccggcg tggtcacgtt
      961 cctcgcctcc gacgccgcgg cctacatcaa cggtgccgtg gtgccggtcg acggcggcct
     1021 cggcatgggc cactgacctt gaacgacgag aggacaccca gcacgatgac cggactgctc
     1081 gaaggcaagc gcctgctgat caccgggatg atcaccgacg cctcgatcgc cttccacgtc
     1141 gccaagaccg cccaggagca gggcgcgaag gtggtgctca ccgggtttcc ccggatgagc
     1201 ctggtcaagc tgatcgccaa gcggctgccg gccgaggcgc cggtgctcga gctcgacgtc
     1261 accaacgacg agcacctcga ctcgctcgcc gaccgggtgc gggagcacgt cgacgggctc
     1321 gacggcgtcc tgcactcgat cgccttcgcc ccgcagacct gcctcggtgc accgttcatg
     1381 gacgcgcccg ccccggacgt ggcgaacgcc gtcgaggtct ccgcgttctc ctacaagtcc
     1441 ctggccaagg cgtgcctgcc gctgatgacg aacggcggct ccatcgtcgg catggacttc
     1501 gacgcccgcg tcgcgtggcc cgcctacaac tggatgggcg tggcgaaggc ggcgctggag
     1561 tcggtgaacc gctacctggc gcgggaactc gggccgcagg gcatccgggt gaacctcgtg
     1621 tccgcgggtc cgctcgccac catggccgcc aagtcgatcc ccggcttcga cgagctgcgc
     1681 gacgcctggg acggccgggc tccgctcggc tgggacgtca aggacgcgac gcccaccgcg
     1741 aagaccgtgt gcgcactgct ctcggactgg ctgcccgcga ccaccgggtc gatgatcatg
     1801 gtggacggcg gcgtgcacgc gatggggcag tcgtagcgat gcaggtcgac gcgctgctct
     1861 ggctgtcctt cggcggcccg gagggtcctg aggacgttcg tccgttcctg gagaacgtga
     1921 cgcgtggccg gggcgtgccg cccgagcggc tggacgaggt cgagcagcac taccagcact
     1981 tcggtggggt gtcgccgatc aacgcgctca actgtgcggc catcgaggcc gtgcgggccg
     2041 aattcgcggc cgcgggcatc gacctgccga tctacttcgg caaccgcaac tggcacccca
     2101 tggccgcgga cacggtcgcc gagatgaccg ccgccggggt gaagcgggcc ctggtgttcc
     2161 cgaccagcgc ctacggcggg tactcggcgt gccgccagta cgacgaggac atcgtggcgg
     2221 cgcgagcctc ggtcggcgcg gacgcgccgg aactggtgaa gctgcgccac ttcttcgacc
     2281 acccgctgtt catagagtcc tttgtggact cggtgaaggc ggccgcggcc acgctgtcca
     2341 cccaggacta ccggctggtg ttcacggcgc actcggtgcc gctgtccgcg gacgccgcgg
     2401 ccggaccgcc ggaggagggc gggcaccggt actcgcggca gatcgccgag gccgcccggc
     2461 tggtggccgc gggtgtcggg gtggccgact acgacgtggt gtggcagtcg cggtcgggcc
     2521 cggcgcggat cccgtggctg gagccggaca tcgtcgacca cctcgatgcc ttgcacgcca
     2581 aggggatcgg tgccgtagtg gggtgcccga tcggcttcgt gagcgatcac ctcgaggtcg
     2641 tgtgggacct ggacaccgag gcccgggagc gggccggcga actcggcatg gagttcgccc
     2701 gcgcggcgac gccgggtgcg gatcggcggt tcgcgcagtt ggtggtcgag ctggtgcgcg
     2761 agcatctcga cggggctccg gcacggaagt tgtcggagtt cccggtggcc gggtgcacgg
     2821 tgaacggcgc gatctgtgcg gtcgggtgtt gcgagccggc gaaacgtccg gcacgaccgg
     2881 cgtgagccag ttgaggacaa ttactcacga gatcgtgacc gccggccgat agcgtcggac
     2941 cgtgactcgg ttacgtggtg ttgtcgcggt tgtttgtgcg gtgctgttga ccgcgtcgtg
     3001 cggcgcggtg tccacggcgg gcaaccagga aaccgaccgg cagtcgcaga cgctcgccga
     3061 cgcgatcagc tatccgcgcc aggagaacgc cgccgccttc gcgcgcgccg cgctcgccac
     3121 cacgctgggc aagaccccgt cgttcagcgt gctggaggcg acggaccttc cccacaccag
     3181 cctctcggag ccgatggcgc ggctggtttg gcgcatccac cacgacgcca ctcacagcgg
     3241 ctacggcgac gagcccgaac tcgacgcctg ctaccgcgtc gagttcgact actacggccc
     3301 cagctcggga cccacgcggg tcacgtgccc ggccggcgcc accccgatca cgccgccgcc
     3361 gctgccgggg cgcgacatcc cctcgaccta cgcacccgcc ctgaaatcgg tccttggcaa
     3421 gctgccggac cggcccaccg aggccgacgt gcgggccgcg ctcaccgccg ggttgcccaa
     3481 gccggtggtg aacccagaga ccggcttggc gaacgtccca ccacaggtct tcgtcgaggt
     3541 ccgcggcgtc gacgtgggcg tggccctgtt cgctcgcacc ggcgtcgaat cgaaggactg
     3601 catgatgggt catcgcgtcg gcggcaccgt cgcggtgtgg tcgctcaacc agcgggagct
     3661 gacgaccaat ggagagcccg tgcaccactc gggccgcgtt gagcaccggc tagcggatcg
     3721 ctgccaggta ggcgatcccg cgcggcgaca gcttgtaccc gacgggcaag ctcaaggtga
     3781 gccccaggtt cttgagcttg cgaacgtcca ctttgaacgg tgccgtctcc cgtccgaagg
     3841 actccgccag gtcgggtgct cgcacgcccg ggcgcgcctc gatcgctgcc agagtgggcc
     3901 ttgtccaagg gccccgggca ctcgcggcgt cgagccggtc caggcgggcg gtgatcgccg
     3961 cgacgtcgtc ggcggtcagg tcggccgtct cggcgagcac cgtgcgcgga tccgggtcgg
     4021 tcacggggtg gatccgcatc aggtagaccg gcgacgacgg atcgccgcgc aggtcggacc
     4081 gggcggcgtc ggcgctcggg tagcctgcgg cgcgggcatc ggtctcggcc agcgttgccg
     4141 ggtcgatccg ctcgatcgag gacacgccga tcatgcccgc cgccgtgcgg tagacgccgc
     4201 ccgcgctggc ctggcgctgc cgccaccggc gcagcagcac ggtgatcgag ccgtcgcgga
     4261 tgccctcctg gagacggcgc tcgatcagca cgcggttgtt ccactctgca gttgacaatg
     4321 aacgagccgg attcggctgc tctcagtctg ccacagattc gaacatatgt tcgaacacga
     4381 tcgagtgaac atgagctagc ggcgttcggc gtggtcggac agcacgcgca ccgcctcgtc
     4441 gaccgccgcg gaccgggccg tgcgcacggc gtcgtgcacc ggtcgcaggg cctccgaacg
     4501 ccggatcgcg gccgacgacg acaacgcgcc gccgggctcg tcctcggccg cgagggcgat
     4561 catcacgccc acctcgctcg cccgctgcag cacccgcaaa gcccgcggtg gcatgccatc
     4621 gggccaaggc gaacgggtcg cgagacggag caacgccgcc atctcctccc gcacgccggg
     4681 ccggtctcgg gcgacgtcca gctcggccaa cgcgcccgcc gcgtcccgca cggcctgcgt
     4741 gagcccgtgc tccgcctcac cgatcggcac gtgctcggcg cgcggcggct ccggcaggtc
     4801 gaacacggtc cagcgcagga tgccctcggc gacctcctcg gtcaccacgc ccagcgccgc
     4861 accgccgaac acggcggcct cgccgtggcg taaggcggcg gcggagaagg cactgcgacc
     4921 gcccagtccg cgcacgtcac cgggcacggg caggacgagc cgcgccgact ccgcgccacc
     4981 ccggcgcaac gcgccgagca gcgcggcggg cgtggccgcc ggctcgccgt cggccggcag
     5041 gtcgagcacg gtggcggtgc cgtcgtcgtc ggccacgacc tcgtgcatcg gcgcccagtg
     5101 cgccatggcg tcgaggacgt cgtccggcgc tgcgttgccg ctgagccacg cagacgtcca
     5161 gacggcgaaa gtcgtcatcg aggtggacac gatctgcgag ggtacgcgag cccaccgaca
     5221 cccgcctcaa tcctcggcag tgcccacgtg ttcgcgcagc aaggcgtcga aggcgtcgcg
     5281 gccgtccgcg ccgaacgccc gtgccggcac cgggtacatc tcgccgaccg acgcccccgt
     5341 gcgcaggacg tacccacgcc gggtccgctg ccaccccgtg acctgcggcc agcgcaactc
     5401 ggtgtgcgcg gtgccgtcca cggtcatcat ccgcatcgcg tgctcgtcgg cgaccgccgt
     5461 gacctcgctg gacgccaccg ggttggctcg gaaggcgctg tagacaccga ccaccgggat
     5521 ggcggcgacg accacggccg cgcacaaccc gaaaccacct gccaccaact gccccacgac
     5581 cagcagcaca acggaaccgg cggccagcac gcccgcgaac cacggcgccc accggtacac
     5641 cggcagcgtg gcgcgcaagg cgtccgtcca atctgcgggt ttgggccacc agcggaactc
     5701 gacccggtcc ttttgcgtca tcacgccaaa ccgtaaggcc tcccgccccc actgtcctgg
     5761 agttgctcca tgtcgaccgg cagcgaacac atgcgtagcg tcgtagtcgt gaacgaagca
     5821 ccgagcaacc tgccacgcac ggcgggggag ttgcgcgccg cggggtacct gccgcgtggc
     5881 gtgaagaccg agatcaagga aaacctgctg gccgcgctgc ggtccggcgc ctcggcgtgg
     5941 ccgggcatcg tcgggttcga cacgaccgtg ctcccgcagc tggagcgcgc cctgctcgcc
     6001 gggcacgacg tggtcctgct gggggagcgc ggtcagggca agacacgcct gctgcgcacg
     6061 ctggcgggcc tgctcgacga gtggacgccg gtcatcgaag gctccgagct gggcgaacac
     6121 ccgctcgagc cgatcacccc ggcgtcgatc cgccgcgccg ccgagctcgg cgacgacctg
     6181 ccggtggcct ggcgccaccg cagcgagcgc tacgcggaga agctcgccac cccggacacc
     6241 agcgtcggtg acctgatcgg cgacgtggac ccggtgaagg tggcgcaggg ccgcagcctg
     6301 ggcgaccccg agaccatcca cttcggactc gtgccgcgag cgcaccgggg catcgtcgcg
     6361 gtcaacgagc tgcccgacct cgccgagcgc atccaggtcg cgctgctcaa cgtcatggag
     6421 gagcgcgaca tccaggtccg cggctacacg ttgcggctgc cgctggacgt gctgctggtg
     6481 gccaccgcga atcccgagga ctacaccaac cgtggccgca tcatcacccc gctcaaggac
     6541 cggttcggtg cggagatccg cacccactac ccgctgagcc tcaagggcga gatcgcgttg
     6601 gtgcgccagg aagccgagct gtccgccgag gtcggcgagg tgctcctgga gatcatcgcg
     6661 cggttcgtgc gcaacctgcg tgagtccgcc gcgatcgacc agcgctcggg tgtctcggcc
     6721 cggttcgccg tggccgcggc ggagaccgtg gccgccgcgg ccctgcggcg ctcggcgctg
     6781 acgggtgagg acgagccggt ggcccgcccg atcgacctgg actcggtgcc cgcggtgctg
     6841 cgcggcaagc tcgagttcga gtccggtgag gagggccggg agaccgagca cctgacgcac
     6901 ctgctgcgca aggccaccgc cgagaccgcg cgggccaagt tcggcggtct ggacctgcgc
     6961 ccgctcaccg atgcggtcgc cgacggccac ctggtcgcca ccggcgagaa ggtgccggcg
     7021 atcgaggtcc tgcaggcgtt gccggagctg ccggtgctgc acgaggtcgc ggcccgcgtc
     7081 ggggtcaagc ccgacgacaa cccgggccgg atcgccgcgg cggtcgagct cgcgctcgaa
     7141 ctgctgtacc tgcagcgcaa ggtggccaag gacgccgagg acggcacggc ggtgtacggg
     7201 ccgtgacggc gccggaccgg tactcctacg ggccctacca cgaggggccc gatccactgg
     7261 cgccaccggt ggacctgagc gcggcgctgg aggacatcgg gcgcgacgtg ctggaggggt
     7321 cgtccccgcg cagcgcgatg gaggagttgc tgcgccgggg cgtgcgcggc acgcaggggc
     7381 tcgacgacct gacccggcgc ctctggcagc gccgtgccca gctgcagcgg cgcaatcggc
     7441 tcgacgggac gatgcagcgc gccaaggaac tgctggacaa ggcgctcgag gccgagcgtc
     7501 ggacgttgtt ccccgacccg tccgacgacg cgcggttccg cgaggcgcag ctggacgcgt
     7561 tgcccaccgg cacggcggcg cagatcaacg agctggcgca gtacgactgg caatccgacg
     7621 aggcccgcga ggcctaccag gaactgcagg acatgctggg ccagcagctg atggagtcgc
     7681 ggttccaggg catgaagcag gcgctggagc agtcgacgcc cgaggacgtc gagcgcatcc
     7741 gcgagatgat gaccgacctc aacgacctgc tgctgtcgca cctgcgtggc gaggacacga
     7801 aggacaagtt cgaccggttc atggccaagc acggcgagtt cttcccggag aacccgcgca
     7861 acgtcgagga gctgatcgac gcgctcgcgc aacggtcggc cgccgcgcag cggatgatga
     7921 actcgatgtc cgaggagcag cgcgccgaac tcggcgagct gatggggcag gcgttcggcg
     7981 atcctcggct ggcgcagcag gtggccgaac tggacgccaa cctgcgtgcg ttgcggccgg
     8041 gcgaggactg gcagggcagc ggccggttcc gcgggaacaa cccgatggag ctgggcgagg
     8101 gcgtgcaggc catgcaggac ctcgccgaga tggacgcgct ggccgagcag ctcggccagt
     8161 cctacccggg ggcccggctg gaggacatcg acctggactc gttgcggcgc cagctcggcg
     8221 acgaggcagc ggtcgatgcc cgtcgactgt ccgaactgga gcgtgagctg cgtgcccagg
     8281 gcttgttcga gcgggccccg gacggctcgc ttcgcttgac gcccaaggca ttgcgcaagc
     8341 tcgggcagac ggcgttgcgt gacgtggtga cgtcgctgcg gtcgcgcaag ggcgagcggg
     8401 acacggcacg tgccggtgcc gcgggcgagc cgacgggttc gtcgcggccg tggcagttcg
     8461 gcgacaccga gccgtgggag gtctcgcgga cggtgcgcaa cgccgtactg cggtcggtgt
     8521 ccacgggttc cggcgcggtc gacctcgatg tgtccgatgt ggaggtcgtg gagaccgagc
     8581 agcgggcgcg ggccgcggtg gcgttgtgcg tggacacgtc gtggtcgatg gtgcaggacg
     8641 ggcgctgggt gccgatgaag cgcaccgccc tggcgttgca ccaattgatc aagacacggt
     8701 tccgcaccga tgcgttgcag ctgatcacgt tcggccggca cgcgatgaac gtggacctcg
     8761 ccgaactcgt cggcctggag ggcgtgtggg agcagggcac gaacctgcac cacgcgttgc
     8821 tgttggccgg gcgccacctg cgcaagaact ccgacgcgca gccggtcgtg ctcgtggtca
     8881 ccgacggcga gccgaccgcg cacctggaac ccgatggcga ggcggaattc cactacccgc
     8941 cgctgcccag gacgctgcgt tcgaccatgg cgcaagtgga cgcgctggcc aagctgggcg
     9001 cgtcgatctc ggtgttcatg ctgggcgacg acccgcggct ggcggagttc gtggacctgg
     9061 tcgcgcgccg gggtggcggg cgggtgatcg cgcccgacct cgacggcctc ggggccgctg
     9121 tggtcggcga ctacctgcgc tcgcgccgcg cccggtagtc cacagtggac agatcggagc
     9181 gggctcgcgc cgccgtggcg gcggcgcggg ccgagacgat ccggttgatc gaggccctgg
     9241 gcgggcgctg gcaggccatc gtcgacgcct cggcgctggc cgcggacgac gacgagcacg
     9301 atcccgaagg cgccaccgtc gccttcgaac gcgcgcaggt cgggtccacg ctggtggcgg
     9361 cgcaggcgga actggccgaa ctcgacacgg ccgccgcccg gatcgcggac ggcacctact
     9421 ggacgtgcac agcctgcggt gggccgatcg cgcaggatcg gctcgaggcc aggcccatgg
     9481 cacgcacgtg catcgcgtgc gcccgaacgg ccgatcgcta gtcaggcggc ggactcgtcg
     9541 gcctgcatga gcccgaagat gttgccctcg gtgtcggtgc agtaggcggt gtaaccgaga
     9601 ccgggcagcg cgctgcgggg caccacaacg gttccacccg cggccaggac cgcggccagg
     9661 gtggcgtcga ggtccgcggt gtccatcgtc agcgggaacg cggcgaccgg ggcgtccgcg
     9721 gccggtcgcg gtccgcgccg gggcaccatg ccgccgtcga tgccaggccc ctcacccgtc
     9781 tggatcagcc agtaggggtt ctcgccccac cgtcggaatc gccagccgaa gacgtgctcg
     9841 tagaaggcct gagcccgggc cggatcggcg gcgtggatct cgaagtggac cgggcggggc
     9901 atgacatgct ccagaaagtg cggggctggc ggaagcgcca ccgtacgcga gcgatcaccc
     9961 cccaagtagg ggccgttggc ctacaaccac ccgaaaaggg tcattcttcg tccggtgtga
    10021 ccggcggcaa ccacggccgg gaaccaccgt ggcgcagccg gatcaccgtg ctgagcacac
    10081 ccgcgacccc gatgtcgtgc cctgccatcg cggtgcggcc ggactcgtcg cacaccaccg
    10141 tccggccgta ccggtgcgtt gtccgggccc gcaacgcggc cagcccgtgc caggccgcgt
    10201 cgcgggggtc ggggtcgccg gtggcctcgg cgaggtcgag caggaagtcc atgccgccgg
    10261 cgacgccgtt cgcgacggtc ggcgggcggg tccactgctc ggcgcgcacg ggggtcgcga
    10321 tggcctgtgc ggtctcgagg tgccgggggt cgccggtggc cgcccaagcc cgcaccagga
    10381 acgtaccggt gcccgcgtgg tcgtggactg cttgcccaca caggaaatcc gcggctcggc
    10441 gggcgatcgc gaggtagcgc tcgtcctcgg tggcgcgcca gcagtccagc aggaacgtgg
    10501 cgatgcccgc ggttccctcg gcgaagcccg tctggacgga ggcatcgggc agccaccaca
    10561 ccggttcggt gtcgtcgacg gtggccagca ggtgttccgc gcagcgcacg gccttgccga
    10621 gcaacgccgg gtcgccgcag gcgcgccagc agtgcagcat cgccagcccc gccccggcga
    10681 tgccgcggtg cacgccggga tccggtccgt gcaccgggat gtccccggcc agctcgagcg
    10741 cgcggtcccg caaacgcctg tcctgcacgg cttgcgctgc ctcgagcaac gaccacacca
    10801 caccggagcg gccgtggtgc agccccggca ggaccgtcgg ttcctcggcg caccggtccg
    10861 ccgtccacca ggcggcgcgc tggaccgcgt cgaacagcag gccgtcgcgc aggtacggca
    10921 tggctcgtac caaggcgttc agcacaccgg ccgaaccaca gtggacgatc gtcgggtcgg
    10981 tgttggcttc acccggccaa agccggtccg cgcccggtcc ggccatcgcc gcgagcaggt
    11041 agccgacgcc gtcgcgcacc agctcgtcgg cggcttcttc gccagggcgc gcggcgggtg
    11101 gtgcaggtgc gacgacccgg cgggtcagcc gttcggcgac ggcgtcgagg ccgcagcggt
    11161 cttgcgggtc gtcggccacc aggtcgagga tcaacggccg gtaccggcgg acgaggggat
    11221 tgtcgacggc cgcgccgtcc agccagggcc gcagccgacc acgtgcgccg cgttccggat
    11281 attccttggc cagcacgggt tccgcgccga cagcgaggaa gaacagcatg gcgcccaagg
    11341 agaacaggtc ggccgcagga tcggccggag tggggaccgc ggcgctggcg agttgttcgg
    11401 gcgcggcgaa tcctcgtggc cccgcgccgg tcacctcggc gccggccggc gcggccatgg
    11461 cgagccggct cagccgcagg gtgccgcctg gttcgacgac cacggtggcg gggctgaggt
    11521 cgcgcagcac gacgccttcg aagtggatct gggccagcag ttcggtgagc tggatggcga
    11581 ggtcgtggcg ttgctcgccg ctcagggtcc gcacgtggtc ggcgagcggc gtgccctcga
    11641 ccgccgaggt gatcaggaac gtctggcccg accgttcgtg cacggtgacc aggtcgggca
    11701 cgagcccggt cgggccgagc agggcgagca tcgcggcctc ggcccgcaac cggtcgcgca
    11761 agtcgccggc gggcgtctcg tcgacgtggg cgcggccgcg ggtgacgacc acctcggcgc
    11821 cggtgctgcg gtcgagcgcg cggaaccggt cgcccgcgcc ccgcggcacg aaccgggtgc
    11881 cgagcggatt gggcatgggc gccgatgggg cgccgatcgg gtcgggcgac cacggcggca
    11941 gccacagctc gggccggtcg ggcaccgccg agccgtccgg tgcgtgcacg acctgctcgt
    12001 agcggccgct gtcggcgagg cggcgcaggg gcacgaacgc ggcgtagcgg tagtgcacca
    12061 ggctgcccgc gcacaccggc cgcgcggagg tgatgaccgg tccgggcagg ccgcgggtgg
    12121 ccgcgtccag ctcgcgggcg agctcggcga cgtcgtcatc ggagttcggg tagatggtca
    12181 ggaaccgggc ggcgacggcg aggtcggcgt cctgtgcgtt cagcgcgcgc accgcggaga
    12241 tcgtcgcggc gaaggtgaac gggcagcggc gcgcggccag gacctcggcg gtgcgggcga
    12301 ggaccatgcc cgcgctggtg gtggtcgccg agacggcgag gagccatccc tgcgcgcgca
    12361 gggcggtgcc gtcgggcagg gcgagcacgc gggtggcgcc gcggcgcagc gaccagccgt
    12421 cgccgagcac gcgggcgacc agtcgatccc acgagccgcg cacggggccg cagcgggtga
    12481 gcggcggtgc gtgcacggcg ggcctccggc ggtggcgagc tggactgatc cagttcgacg
    12541 gtgaatcagc gcgggccgcc gtgcacgtgg ttgggatgat ccggaatcga agcggcagag
    12601 ttcggtgacc gatcgggcgg ttttgtcggt gggggccgtt agcctgcgcg catggcgatc
    12661 aaagtgcagg tgacgttcga cgcgcacgac gcggaagcgc tggcctcgtt ctggcagctg
    12721 gccctcgact acgcggagca gcagcccccg cccgggttcg cgacctggca ggacttcgcg
    12781 gcgaagatcg gcatgcccga ggagaagtgg cacgccttcg gcgccgccat cgacccgtcc
    12841 ggcgccggcc cgcggctgtt cttccagcag gtgccggaag gcaaggtcgc gaagaaccgg
    12901 gtccacttgg acctgaacgt cagcggcggc ccgaacagcg gggaagaggg ctggaagcgg
    12961 gtgctggccc actcggagaa gctcgtggcg gccggtgcgt cggtgcagta cgagagcaac
    13021 gaacccaacg gtcgctgcct ggtcatgaag gaccccgagg gaaacgagtt ctgcatccaa
    13081 tgaggacaca agtggctttc gactgcgctg acccgcatgc acaggcccgc ttctgggctc
    13141 aggtcttcgg gacggtcgtg gaggaccacc acgacctcgt cgagcagttg gtggcggccg
    13201 gccgcatgtc cgccgaggaa cgcatcgttc ttgaccggcg gtcggctttc cgggacgtgg
    13261 cggcggttcg ggatccgtcc ggtgtggagc cccggttgtt cttccagcgc gttccggagg
    13321 gaaagtcggc gaagaaccgt tgccatgtgg acatccacgt ggacgaggcc gacaaaccgg
    13381 ccgaggtgga acggttgatg gcgttgggag cgcgccacct cgagacccac gccgaccgag
    13441 gtcccaccgt ctacgtgatg caggacccgg agggcaacga gttctgcctg cattgagtca
    13501 gctggtgatg tcctttgtgg tgaagcggcg gaaggccaac gtgccgaaga ccaggccgta
    13561 gatcagtgcc gagagcgttc ccttggccag gttcgtccag tcgatgtcgg tggcgatcag
    13621 gtccgaccac gagaaggcga agtgcgtcgg caagtactgc cgcagtgagc ccagcgccgt
    13681 gatctgctcg aggatctgcg acaggatcga caccaggacc gcgccgccga cggcacccag
    13741 cggcgcgtcg atcagcacgg acaggaacat cgcgagcccg gccacccaga tcagctggat
    13801 cgagatgtag accaccgaca tgccgatcgc cgccagcgcc gtggggaagt cgacggcgtc
    13861 accggtgggg gtcacggctt cgcctgcgcc gtagctcacc aggcccacca ggaacgccac
    13921 cagcggcagc aacaccaatg cggcgaacga aagcaccgct gacgcgagtg ccttctgcgc
    13981 cagcaaccgg tgccgcggca cggggatcgc cagcaggtac ttcaggctcg accacgaagc
    14041 ctcgctggcg atcgtgtcgc cgaagaacag cgcgacgatc atcggcagca ggaacgtgcc
    14101 cgacacgaac aacgtcagca ccacgaagtt cggggcgctg gccgtcgcca ggtcgacgaa
    14161 gccgcccgaa cggcggttgg ggttcgaaga accgacctcg aacgccaccg ccagcaggaa
    14221 cggcagcagc acgaggaacc cgtacagcaa ctgggtccgc ctgcgccgca actgccggcg
    14281 cagctccacg tgcaaccgca acgtgcggcg cgcgcggtag ccctcgaccg cgccgctcgc
    14341 gccggcgccg aggtgcgagg cacgcgccgc gtcggtcagt tcggcgatcg ccgccggatc
    14401 ggtgtggacc gactcgtccg cctccgtcat gagtcctctc cgaccagttg caggaacacg
    14461 tcttccagcc tgcgccgcgg cccggcctgc tcgaccgcca cacccgccga caccagcacg
    14521 ccgatcgcca ccgaacgcgg cgtgccgtcc agttcggcgt gcaccgcgct gccgtcgacg
    14581 gccaccccgg tcacgcccga gatgccgcgc agcacgtccg cggccacgtc cgggcggtcc
    14641 acccggaacg tcgcctcgcc gccaccggac acgatctcgt ccaccggccc ggccgcgacc
    14701 aaccgaccgc ggtgcatgac caccacgtgg tcacacgtct gctcgacctc ggcgagcaag
    14761 tggctggaca ccagcaccgt ccgcccggtc gccgcgtacg cacgcagcac cgagcgcatc
    14821 tggtggatct gcggcgggtc gagcccgttg gtcggttcgt cgaggaccag taggtccggc
    14881 aagccgagca tggcctgcgc gatcgcgagc cgctgccgca tgccctggct gtacgtgcgc
    14941 accttgcggt tcacggcctt gccgagcccc gcgatctcca gcgcctcgtg gacgtgcgcg
    15001 cgctccgcgg gtcgcccggt cgcggcccag tacagccgca ggttgtccgc gcccgacagg
    15061 tgcggcagga agcccgcacc ctccacaaag gacccgatgc gggacagaac cggtgcgccg
    15121 gggcggatct cctggccgaa caccttgatc gtgccgccgg tcgggtggat caaccccatc
    15181 agcatgcgca gcgtcgtggt cttgcccgcg ccattcggac cgagcaggcc gaggacctgg
    15241 ccgcggtcca cccggaaact gaggtcgtcc acggcgacca agccgccggg gtagcgcttg
    15301 gtcaggccgt cgatcaccag cggcacgtcg gtgagctcgg ggtcaggacg gccggaccgc
    15361 ctgcgccgca aggcaaccgc gagcacgagc agtaccccga tacccagcac cacgatgatg
    15421 ccgatcaccg ggccgaccgg cgccgggccg cccacgttcg tcccgggcac gaccggcacc
    15481 gcgatggtgt cgtcggccaa ggcgatgcgg taggcggcgg gctccagcgg tgtggcgtag
    15541 gactggtcgg tggtggtgac gaccaggctc aggtagtgcc cggactcgac cggccgcacg
    15601 atgcccggca gggcaacggt caccttcacc gagtcgccgt taaccggtag tggtggcact
    15661 cgcaccgggg agaccgcgga gccgggcagg atccgcgtgc cgtccggtcc gacgtcgtag
    15721 agcttcgcga acaacacggc gcccgtcttc gacggtggca gcccgggcat ggcggagacg
    15781 tccagccggg cggtggccga gccggcgatc agcagctgct cgtccaaggt cggtccggag
    15841 aagatcgcag actgcccggg cagatcgatc gaggtccggc cggacagccg cccgcccgcg
    15901 cccgcgagca ccgacgaaag gccaggcaag ctgctcaccg aacccgggtt ggccccgggc
    15961 gggttgatca cggtctgcgc ggcgccgctc atggccatgg cctggcgttg caccggggcg
    16021 ccggtcagcc cggggtacgc gggcgcgcgc accacgcgca ccgacggcgc gccctgggca
    16081 cgcaacgcgc cctgcaccgc gtactcgaag ccggtgccgg gatcggtgcc gcgcttgtcg
    16141 agctggtagg cgagccagtt gcgcatctcc tcccgcagct gcggacccgg ccggccgccg
    16201 tcgtgcccgc ccgcgtacca gatcaccttc accgaaccgc ccgccgcggc gatctgccgg
    16261 gcgttggcgt cggcctggtc cagcccgaag agcgtgtcct gctcgccctg caccagcagc
    16321 gtcggctggg tgatcttcga ggtgaccgac accggcgaca ccgacttgag cagcgccacc
    16381 gtctccgcgc tcggcacacc ggtggtcgcg acttccgcgt aggccttgca gacgtcgagt
    16441 ccgaaccgcc cgcacggtcc gccggtcgcg cccgcgggcg gggcgtcgcc gccctggtcg
    16501 ccacccgcgg tgtcgccgcc ggtcgagggc gcgggtgcgg gcgccgccgc gtccccgccg
    16561 gccgcggcgt ccgaggagcc ggacacggtt ccgggctcgg gcgcctccgg gcccgagctg
    16621 cccgcgtccc cgccgccgcc catgccggac gcgaagaaga tcccggccca cgcccgcttg
    16681 aacacaccgt cggccccgaa gggcccggcg gccggggtgc cggccggcat cgcgccggta
    16741 cttccggtgt tcggcaacag cgcctgggac aagtcgttgt aggtgatcac cggcgcgagc
    16801 gcgtcgaccc gcttgtcggc cccggcgagc atcagcgcga gcgcgccgcc gtacgagccg
    16861 ccggtcacgc cgacccgcgg gtcgcccgga ccgtccaaac gcacctcggg ccgcttcgcg
    16921 agccagctga cgagttgctt cgcgtcctcg acctcgtagt ccggggagtt cagctcgatg
    16981 gtgccgccgc tgcgcccgaa gccccgcgcg gaccacgcga gcacgacgaa gccctgcgcg
    17041 gcgaactccc gcgcgtcggc gtccacgctg cgcttcgacc cgccgaaccc gtgggcgatc
    17101 atcaccgcgg gagcaggggt cttttcgggc aggtaaaggg tggtgtcgat ggccaccggg
    17161 gcgcgtttgc ccgccgggcc gtcgacaagg gtgagcacct tctcctgggt gcggacctgc
    17221 tgcccggtgg acgacggccg ggtcaccaac accaccgtga tcacgatcaa ggcggcgacc
    17281 acggcaaacg cggtccaacg gaagacggat cgggggatgc ggcgcacgtc gcccaaggta
    17341 ttcgagtgaa gctgagaaga ttgttagtga cccgatcggg taccccaacg ggttgtgatg
    17401 caggacaacc ccctgtatcc agccgttcct ctggcgttat tgccaggcgc acgcgacaat
    17461 ggagggacgt ggaggggagt actccctaag cgccggtgtc gtcagcacgg atccgcctcg
    17521 ggtcccggtg ccggtggccg gccggaaggc cggtggagga gacctccggt tggtggcgtg
    17581 cgcacaaaag caggtgcacc cggaaaccgg aggtcaacgc tcgtgatcgt ccccgcctgg
    17641 atctggctcg cgaccatcgt cggcttgctg atcctgctcg ccgtcgacct ggtcatcgtg
    17701 gaccgcaaac cgcacgaggt gaccgtcggc gaagctgcca ggtgggttgt cttctacatc
    17761 gcgtgtgccg ccgttttcgg tgcggccctc tgggcgttcg ccggcaagac acccgcgatc
    17821 gagttcttct ccggttacat caccgagtac tcgctgtcgg tcgacaacct gttcgtcttc
    17881 gtcgtgatca tgggtgcctt caaggtgccg gtggtccacc agcaccgcgt gctgctggtc
    17941 ggcatactga tcgccctcgt gatgcgtggt ctgttcatcg cggccggtgc cgcggtcatc
    18001 gaccggttca gctgggtctt ctggctcttc ggcgcgttcc tcgtcgccac cgcgtacaag
    18061 atggcccgct cgggcctcgg tggcgaggaa gacgaggagt acaaggagaa cgcggcgatc
    18121 cgcgtcatcc gcaagatcgt cccggtgtcg aaggactacc acggctcgaa gtcgttcgtg
    18181 cgcctgtccg gccggcgcct cgtcacgccg atgttcgtcg tcatgttcgc catcggcacg
    18241 acggacctgc tcttcgcgct cgactcgata cccgcgatct tcggcctcac caaggagccg
    18301 ttcctggtct tcgccgcgaa cgcgttcgcg ttgatgggtc ttcgccagct gtacttcctg
    18361 ctcggtgggt tgctgcaaaa gctggtctac ctctcgatcg ggctctcggc gatcctgggc
    18421 ttcatcggtg tgaagctcat gctcgaggct ctgcacgaca acacgctgcc gttcatcaac
    18481 ggtgggcagg gcgtgcacgt gccgaccatc agcatcacgc tgtcgctgtc cgtgatcgtc
    18541 ggtgtactgc tgatcaccac cgtggccagc ctcatcaagg ctcggcggga ccccgattcg
    18601 gtgcgcaaga cccctggact gcccggtggg gacgatgccg atgcctcgga acaacgcagc
    18661 gcccgtgagg cggcctgacc ggcattactg gtaacggtaa gttcctaagc tttgctaaag
    18721 agcgagtagc ctcggccgca tgcgccctga ggacatcgag ttattggcgg ctcccaccga
    18781 ggtcacggtc cacggcgacc tgaccctggt ggcgctgtcc acgccgaatc tcgccgttga
    18841 cggcaaccgt ggcggcctgc accgggtcga cctgaccggc ggtggcagca cgccgtggac
    18901 ccacggcgac cgggacagcg cgccgacgat ctcgccggac ggccagtggg tggccttcct
    18961 gcgggtgtcc ggtccgaagg gcaaggaacg accgcagctg cacgtgatgc ccaccggtgg
    19021 cggcgaagcg cgtgaggtca cgtcgttgcc ggggggcgcg ggcgcgccgg tgtgggcgcc
    19081 ggactcgcgg cgcatcgcct tctgcacgcg ggtgccggag ccgggtcgct acggtatttc
    19141 cttgccggac aacgactccg aggtgatcga ggcggccgcg gaggcgcccc ggcggatcac
    19201 ccggttgttc taccggctcg acaacgtggg cttcgtcgac gaccagcccc tgcagctgtt
    19261 cgtggtcgac gcgctggccg acgagcccga agccaagcag ctgaccacgg gcaacgccga
    19321 accgggcgat ccggcgtgga gccccgacgg cacgcgcgtc tacgtcgccg cgcgcaagga
    19381 ctggggcgtg gacgacacgc tcatcaccga cctctatgcg gtgcccgccg acggcggcga
    19441 accggagctc gtcgcgagca tcgaaggcga cgccagcttg ccggtcgtgc tcgccgacgg
    19501 cacggtcgtg ctgctcggtg accacacccc ggccgacgag cacggccgac cgcaggccga
    19561 ggcgcgcaac gcgggcgtgt ggtcggtgcg tcccggcgcg gcgccggtgc ggctgaccga
    19621 cgaggaaacc gtcgacgtgg agcggggtgc gggcgcgccg gtgctcgtgc ccggcggcgt
    19681 gctggtggcc gtgcgcaacc ggggcgcgat cgaactgcgt gaggtgccgg tcgacggcac
    19741 cgtccggacg ttgtccgagc tgccggtgct cgccggtgag caggggcagg tccgggcgtt
    19801 cgccgcgcac aacgggcgag tggtcgccgt ggtgtccaca ccggacagtg cgggcgaggt
    19861 ggtcgtcgtc gacgcggggg agagccgggt gctcaccgac ttctccgcac cgctgaaggc
    19921 ggcggggttg cgtccggtgg tggagatcaa ggcggccgcg ccggacgggt acccgacgca
    19981 cggctggctg gtgctgcccg aaggcgacgg cccgcacccg gtgctgctgc acgtgcacgg
    20041 cggcccgttc atgtaccacg gctgggggtt cttcgacgag gcgcaggtgt acgcggccgc
    20101 cgggtacgcg gtcgtgctgg ccaacccgcg cggctcgtcc ggctacgggc aggcgcacgg
    20161 gcaggcgatc gtcggcgcgc tgggcaccgt ggacgtcgac gacgtgctgt ccgttctgga
    20221 cgccgcactg gagcgccccg agtgcgacga gacccgggtc ggcgtgatgg gcggttcgta
    20281 cggcggctgg atgaccggct ggctcgcggc caagcacggc gaccggttcg tggcggcgtg
    20341 gagcgagcgc gcggtcaacg cgtgggactc gttcgcgggc agctcggaca tcggctggtt
    20401 cttcgccgac ggctactgcg gctacggcgc ggaggcgcgt cgcgcggtca gccccctgac
    20461 ctacgccgac gacatccaca tcccgttcgc gatcgtccac tccgaacacg actggcgctg
    20521 cccgatcgag caggcgcagc ggatgttcgt ggcgttgaag aagaacggcg tggacacaga
    20581 gatgctgatc ttccccggcg agggccacga actgacccgg tccgggcgcc cgaagcaccg
    20641 caagcaacgc ttcgacgcgg tgctggagtg gtggtcgcgc cacctgccgg tctagtcgtt
    20701 gacggtggcc ccggcctgtt ggtacagacc ggggccgctc acccgcaggt cgtgcaggaa
    20761 agcactcgcg gcaacataag cctcgccgag cagttcggcg gtgtgcgtga agtccaaagg
    20821 ggacacccgg atcagcggcg gtcccgggag gtacaccacc ggtagctcgg cggcgatcgc
    20881 cggtgcttcc agcaccgcct gctggcgcat ggccaccatc gccaccatga acaccacttc
    20941 ggcgatggtg cgcggcgccg cgggcaggcg gctggggaac gcgcaatcca gcaccaccaa
    21001 cgacttcgcg cccatggcga ccgcctggcg catcggcacg ttggccacca cgccgccgtc
    21061 gtagtacagg ccgtcgccga gttcgaccgg cgggtagatg ccggggatgg cggcgctggc
    21121 gagcaccgcg ggcttcagcg ggccttcgcg cagcagcacg gcctgcgtcg tcgccacgtc
    21181 catggccacc acgccgagcg ggatggcgca gtcgtcgaag gtcgtgtccg agccgagcac
    21241 ctcgtcgacg agggcgccga ggcccacgct ggtgaacagg tgcgtgcggc tcttgcgcag
    21301 cgtcacggcc tgcgcgagcg ggccgcccgg gaacaccgcg cgacgggtca tcgaggtcca
    21361 gatcgccgac aggcgctcga cgggaatctc cccggcgcgc gccagcaccg cgccgttgag
    21421 cgagccgacc gacgtgccgg tcaccaggtc cggcgtcacg ccgtgttcgg ccagcgcacg
    21481 cagcatgccg acctggctcg cgccgaggct gccgcccccg ccgaggacga acccgacggg
    21541 gcgtggcagc tccagcacgg gcgtcacacc agttcgaggt cgacgtcgat gttgccgcgg
    21601 gtggcgttgg agtacgggca cacctggtgc gccgcctcca ccagctgctc accggtctcc
    21661 cggtcgacgt ccgggatcgt gaccttcagc ttcacggcca ggccgaagcc gcccttgccg
    21721 tccgggccga tgccgacctc ggcggtcacc gacgcgttcg cggtgtccac cttctggcgc
    21781 cggccgaccg caccgagggc gctcgcgaag caggccgcgt acccggtggc gaagagctgc
    21841 tcggggttgg tgccctcgcc gctgccgccc atctcggtgg gcggcgcgag ggtgacctcg
    21901 agcttgccgt cggaagtgct tgccttgccc tcacgcccgg tcgcggtggc gacggcggtg
    21961 tacaggatct tcatcggggt cctttcagct cagctcgacc agcatcttgc cggtgttggc
    22021 gccgcgcatc atgtcgagga acgcctgggg tgcgttctcc agtccgtgca cggtggtctc
    22081 gttgaagcgg atcttgccct cggtgagcca gccgccgacc tcggcgagca tgggcttcat
    22141 ccggtcgccg tggtcgctga cgatgaagcc gcggatggtc agccgcttgc cgatcaccag
    22201 ggcgagattg cgtggcgccg gggtcggctc cgtgctgttg tactgcgaga tcgcgccgca
    22261 gacggcgatg cggccgtaga ggttgagcga ggcaatggcc gcttcgaggt ggtcgccccc
    22321 gacgttgtcg aagtacacgt cgatgccctc gggcgcggcg gccttgagct gctcgcgcac
    22381 gtcaccgtcg cggtagttga acgcggcgtc gaagccgagt tcgtcggtca ggtaggcgac
    22441 cttctcagcc gagcccgcgc tgccgatgac ccgcttcgcc ccgcgcagct tggcga
//
