LOCUS       NZ_SNXZ01000006        31227 bp    DNA     linear   CON 20-APR-2024
DEFINITION  Labedaea rhizosphaerae strain DSM 45361 Ga0310470_106, whole genome
            shotgun sequence.
ACCESSION   NZ_SNXZ01000006
VERSION     NZ_SNXZ01000006.1
KEYWORDS    WGS; RefSeq.
SOURCE      Labedaea rhizosphaerae
  ORGANISM  Labedaea rhizosphaerae
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Labedaea.
REFERENCE   1  (bases 1 to 498874)
  AUTHORS   Goeker,M.
  TITLE     Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing
            the most valuable type-strain genomes for metagenomic binning,
            comparative biology and taxonomic classification
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 498874)
  AUTHORS   Goeker,M., Huntemann,M., Clum,A., Pillay,M., Palaniappan,K.,
            Varghese,N., Mikhailova,N., Stamatis,D., Reddy,T., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-MAR-2019) Prokaryotic Super Group, DOE Joint Genome
            Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.12.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 180.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004362825.1-RS_2024_04_19
            Annotation Date                   :: 04/19/2024 13:11:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,820
            CDSs (total)                      :: 7,753
            Genes (coding)                    :: 7,690
            CDSs (with protein)               :: 7,690
            Genes (RNA)                       :: 67
            rRNAs                             :: 3, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2 (5S)
            tRNAs                             :: 59
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 11 of 63
            Pseudo Genes (incomplete)         :: 55 of 63
            Pseudo Genes (internal stop)      :: 3 of 63
            Pseudo Genes (multiple problems)  :: 6 of 63
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 17:41:24
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 331010
            Orig. end                         :: 362237
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            SNXZ01000006.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..31227
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /contig_edge="False"
                     /product="NI-siderophore"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="IucA_IucC"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..31227
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="IucA_IucC"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="neighbouring"
                     /product="NI-siderophore"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..31227
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[14000:17227](+)"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      14001..17227
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
     misc_feature    301..316
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 18.21"
                     /tool="antismash"
     gene            complement(330..1724)
                     /locus_tag="EV186_RS30535"
                     /old_locus_tag="EV186_106334"
     CDS             complement(330..1724)
                     /EC_number="3.5.1.4"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1105: amidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009949744.1"
                     /locus_tag="EV186_RS30535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_106334"
                     /product="amidase"
                     /protein_id="WP_133852926.1"
                     /transl_table=11
                     /translation="MSTADLTATELLAAYRSGELSPVQACEDTLARIEQLNPAVNAYLL
                     VDGERALAQAAESAARWRKGEPRGLLDGVPTSIKDILLTDGWPTLRGSKTIDPGQEWKV
                     DAPAVARLREHGAVLVGKTTTPELGWKGVTDSPVSGVTTNPWDPAKTAGGSSGGAAAAV
                     ALGMGPLAVGTDGGGSVRIPAGFSGVFAHKPTYGRVPLFPASAFGTLAHVGPITRTVTD
                     GALMLDVLSGADARDWSAGPPAEPVAKRLADGVAGMRIAFSPTLGYVRVNPEVAAAVAA
                     AVRVFRELGAQVDEVDPGFTDPVDAFETLWFSGAAASVAAFPATSDVDPGLMEIVEQGR
                     GYSALDYLAATSTRMELGRIMGEFHRRYDLLVTPTLPIPAFEAGVEVPAGWSRNRWTSW
                     TPFTYPFNMTQQPAASVPCGFTAAGLPIGMQVVGPRHADARVLTACLAFETARPWTHKK
                     PPLLAT"
     gene            complement(1711..2700)
                     /locus_tag="EV186_RS30540"
                     /old_locus_tag="EV186_106335"
     CDS             complement(1711..2700)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2-Hacid_dh_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1072: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016700180.1"
                     /locus_tag="EV186_RS30540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_106335"
                     /product="D-2-hydroxyacid dehydrogenase"
                     /protein_id="WP_133852927.1"
                     /sec_met_domain="2-Hacid_dh_C (E-value: 4.1e-48, bitscore:
                     158.0, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPPTVTVLHDADKPPAMQGIERDFPVRYCTGESLADALTGAEVLF
                     VWDFRSRALADAWAGASALRWVHAASAGVDHVLVPGVLEGEIVVTNSRGVFDQPMAEYV
                     LGAILALAKDLPTTLRAQGERRWVHRETERIGGKRALVVGTGPIGRATARLLTAAGLVV
                     TGVGRTARAGDPDFGRVLDMSEYRNALPDTDFLVLAAPLTEQTRGMVDATALAALPNTA
                     RLVNVARGPLVVADALVAALAAGELAGAALDVFDVEPLPTDSPLWTMPNVIVSPHMSGD
                     VLGWREELVALFADNLARFTQDRPLRNVVDKRRGYVPSKQSEESHVDR"
     gene            2902..3393
                     /locus_tag="EV186_RS30545"
                     /old_locus_tag="EV186_106336"
     CDS             2902..3393
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016700181.1"
                     /locus_tag="EV186_RS30545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_106336"
                     /product="DUF3830 family protein"
                     /protein_id="WP_133852928.1"
                     /transl_table=11
                     /translation="MSRLMKISLAKRGVSCVARLLDKDAPRTCDAVWNALPLGGDAYHA
                     KYARNEVYTMVERFAEPVGQENPTVTPIPGDVVFFDFNGGMLDRAFKEEKGIDQLPGVI
                     DLAIFYGRNNLLLNGDVGWVIGNVYGTIVEGLEQMAEACNDVWRAGAIGERLVYERLDG
                     "
     gene            3402..4163
                     /locus_tag="EV186_RS30550"
                     /old_locus_tag="EV186_106337"
     CDS             3402..4163
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009949747.1"
                     /locus_tag="EV186_RS30550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_106337"
                     /product="Asp/Glu racemase"
                     /protein_id="WP_133852929.1"
                     /transl_table=11
                     /translation="MTIDNVELIGPELVTQHGIGVVAPFDFALDRELWRWTPDNVSLYM
                     TRLPFVPVPVTIEMASELSDPDRVSRATKDVLAPEPLAVAYACASGSFVHGMLGERLLA
                     KSMVDAGAPAATTTSGGLVEALALLGLRRIAVVTPYIDSVTQRLLAFLGEHGIESVDSI
                     GLGLLSHIWKVGYAEVVQAVRTVDRPDAEAVFISCTNVPTYDIIAPLERMLGKPVLTAN
                     QVTMWSALRAAGFGAIAAEQRLVQATTPTAA"
     gene            4342..5121
                     /locus_tag="EV186_RS30555"
                     /old_locus_tag="EV186_106338"
     CDS             4342..5121
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010693002.1"
                     /locus_tag="EV186_RS30555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_106338"
                     /product="maleate cis-trans isomerase"
                     /protein_id="WP_243754391.1"
                     /transl_table=11
                     /translation="MPHGAEARPNGERANNTAPTIGFLYPGYSAEDDYPAIEAMLGDVR
                     LPVVHTLMREDAHRVDALLDIGGNDVLSVGAVKLRQLGVDAAMWACTSGSFVFGWDGAS
                     EQVDGVREAAGVPASSTSFAFVHAARALGVGKVAVAATYPKDVADRFVEFLAGAGIEVV
                     SLSCRGIVTAAEVGTLGREDVLAFVTANDHPDAEAVLVPDTALHSVRWLDDLEAALGKP
                     VLTANQVTVWAGLRLAGHFEPRTGLGSLFRAGVAQVN"
     gene            5138..5794
                     /locus_tag="EV186_RS30560"
                     /old_locus_tag="EV186_106339"
     CDS             5138..5794
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020670597.1"
                     /locus_tag="EV186_RS30560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_106339"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_133852930.1"
                     /transl_table=11
                     /translation="MSELGELEPITRRSTAAIIADQLRSAIMYGSLPPGSQLGEADLAA
                     KLGVSRGPLREAMQRLVQEGLLRSERHRGLFVIDMDAADVRDVYQARLAIERAACQLVM
                     QGNRGEALATLSAALEGILEAAASRDRIAMSDADQAFHQALVACSGNSRLVRMAQTLLV
                     ETRMCLSALQAHYPEPDELVAEHRALVDAIADGDERLLLELIERHMLDSIDRLNP"
     misc_feature    complement(5929..5948)
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: medium, score: 24.01"
                     /tool="antismash"
     misc_feature    5995..6008
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.65"
                     /tool="antismash"
     misc_feature    complement(5996..6009)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 20.32"
                     /tool="antismash"
     gene            6066..6737
                     /gene="shbA"
                     /locus_tag="EV186_RS30565"
                     /old_locus_tag="EV186_106340"
     CDS             6066..6737
                     /codon_start=1
                     /gene="shbA"
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF007230.0"
                     /locus_tag="EV186_RS30565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_106340"
                     /product="RNA polymerase sigma factor ShbA"
                     /protein_id="WP_133852931.1"
                     /transl_table=11
                     /translation="MRRPREPSGGAPGWCVRREKHVTSGPVVQNSIAPDLKGPDFHKVV
                     VDAQAGDREAIATLFVRLQPAVQRYCRARIGRSGSSYSSADDVTQEICLGVLGALKKFA
                     DDPSSFLPFVYGIASHKVADHYRKAGRDRTDPVADMPDLVDRNVGPEQYALRGDLRAKL
                     LQLMDRLAPRQQEILRMRLIVGLSAQETATAIGLTATAVRVTQHRALNKLRELAAGLDL
                     R"
     gene            complement(7126..8349)
                     /locus_tag="EV186_RS30570"
                     /old_locus_tag="EV186_106341"
     CDS             complement(7126..8349)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018332020.1"
                     /locus_tag="EV186_RS30570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_106341"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_208115861.1"
                     /transl_table=11
                     /translation="MIEPADAVADAHRREWAFVLAATVRVAGDLDLAEECVQDAYVAAL
                     EVWTRQGVPGNPAAWLTTVARRRVMDAMRRSSTLRAKLPLLVEPPSDDPPPRPEAVPDD
                     RLRMIFTCCHPALAREAQVALTLRLLCGLTTGEIADAFLVSEPTMAARVTRAKKKITGA
                     GIPFRVPGPAELPDRLDAVLTVVHLVYTTGHTAPRGEGLVRADLTALAIDLARLVHALM
                     PDEREATGLLALLVLLDARRGSRTDAGGRMLLLSEQDRSSWDRVAIEEGRELVFDALRG
                     GRPGRFAVQAAIAALHAEAPSYEETDWEQVVGLYDVLATVWQSPVVALNRIAALSMAQG
                     PERALAELTELADDPRLADYHYLPATRADLLRRLGRPEEAAAAYREALALTTNPAERDF
                     LTRRLATL"
     gene            complement(8346..8687)
                     /locus_tag="EV186_RS30575"
                     /old_locus_tag="EV186_106342"
     CDS             complement(8346..8687)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018332021.1"
                     /locus_tag="EV186_RS30575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_106342"
                     /product="YciI family protein"
                     /protein_id="WP_133852932.1"
                     /transl_table=11
                     /translation="MAQYLILIYENEESYANATPEVFERVMQAHSRFTEQVPEHGAKLL
                     GGEALQPTPTATTIRGDVVTDGPFVETKEALGGYYVIEAPDLDTAIAVGKLCPAEFGGV
                     EVRPVMVFE"
     misc_feature    8751..8766
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 22.47"
                     /tool="antismash"
     misc_feature    8763..8778
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 21.1"
                     /tool="antismash"
     gene            complement(8775..>9206)
                     /locus_tag="EV186_RS30580"
                     /old_locus_tag="EV186_106343"
                     /pseudo=""
     CDS             complement(8775..>9206)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR03086.1"
                     /locus_tag="EV186_RS30580"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_106343"
                     /product="TIGR03086 family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="AAAASGGARDKSDWEPRRLEEDPHAAFVASAAEATEAFRSIDDEV
                     YLAEFGRAVPGKIAVGFHFVDYLAHGWDVARALGRPDRLSEPDPALTEAGMAIAERIPN
                     EPPSRGPGAAFAYRVDVADTASPHQRLIGLLGRSPEWTR"
     gene            9467..10840
                     /locus_tag="EV186_RS30585"
                     /old_locus_tag="EV186_106344"
     CDS             9467..10840
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008374 - O-acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020497793.1"
                     /locus_tag="EV186_RS30585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_106344"
                     /product="wax ester/triacylglycerol synthase family
                     O-acyltransferase"
                     /protein_id="WP_133852934.1"
                     /transl_table=11
                     /translation="MAIMPVTDSMFLLAESREHPMHVGGLQLWKPPADAGPDYLAELHH
                     RLLATEVRSLFRRRLRGPIGLGQAWRIDDDMDLEYHIRLSALPRPGRVRELLELAGRLH
                     GSLLDRHRPLWEYHLIEGMTDGRFASYTKVHHSLLDGVSALRLLAKSLSTDPDARELLP
                     PWGEPPASEKKGPRANGGPLAGIRGAAKAVGELAGLAPALWQTANDLFREQSASTLASP
                     APRSMLNVPITGARRFAADQWDMDRIRKVSKAAGATLNDVMLAMCSGALRRYLLSYDAL
                     PERPLVAGVPVSLRARKKDSGDSGNAVGLILCNLATDQADPATRLAEIHASMTRGKEFY
                     AGMSPLQITALSALPLIPLAVGVLPGGTKVMSPRFNVLISNVPGPPRRLYWNGAELDGI
                     YPVSIPYEGQALNITVTSYAGRLAFGLTGCRRTVPHLQRLLGYLEDSLTELEKATSGV"
     gene            complement(10850..11050)
                     /locus_tag="EV186_RS30590"
                     /old_locus_tag="EV186_106345"
     CDS             complement(10850..11050)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020640318.1"
                     /locus_tag="EV186_RS30590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_106345"
                     /product="DUF5302 domain-containing protein"
                     /protein_id="WP_133852935.1"
                     /transl_table=11
                     /translation="MSDAPEANENDEATPETEDVKRKFREALERKQAATTARAAHADAS
                     SKVHDSHGRAGGKRQFRRKSG"
     gene            11141..11614
                     /locus_tag="EV186_RS30595"
                     /old_locus_tag="EV186_106346"
     CDS             11141..11614
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009943317.1"
                     /locus_tag="EV186_RS30595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_106346"
                     /product="cupin domain-containing protein"
                     /protein_id="WP_133852936.1"
                     /transl_table=11
                     /translation="MTYLGDTGEISALYRPAAEIQSVVRPLSTSTFVAPGSVTNGQYGL
                     FRWDMRPESGGPDAHFHKTFSEAFYVLDGTVGLFNGDKWVDAKAGDYLYVPEGGVHAFH
                     NKSDAAASMLILFAPGAPREKYFIELAEIAESGRKLTDEEWLELWARHDQYPA"
     misc_feature    11647..11664
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.59"
                     /tool="antismash"
     gene            11709..12164
                     /locus_tag="EV186_RS30600"
                     /old_locus_tag="EV186_106347"
     CDS             11709..12164
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016338025.1"
                     /locus_tag="EV186_RS30600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_106347"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_133852937.1"
                     /transl_table=11
                     /translation="MTRFDAAALTPDQRDVRTAHDALPHIKAYLARHHARDVVRLVADG
                     GDEPLEVPRAAIELLARILTHMAAGQGVSIVPANAELTTQQAAAMLNVSRPFLIKLLND
                     GKIEYRTVGTHRRVLAESLRDYMRAEAQRMSDVASELTALNQEMGLT"
     misc_feature    12000..12002
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            12168..12737
                     /locus_tag="EV186_RS30605"
                     /old_locus_tag="EV186_106348"
     CDS             12168..12737
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020499733.1"
                     /locus_tag="EV186_RS30605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_106348"
                     /product="PIN domain-containing protein"
                     /protein_id="WP_133852938.1"
                     /transl_table=11
                     /translation="MAFVVLYDANVLYPSTLRDVLIRIAQGGLVQAKWTDRILDETFSS
                     IKRNHPDIDIAKLDRTRVLMNQAVLDCLVTGYEPLEHAFELPDPDDRHVLAAAVKSQAQ
                     VIVTENIRDFPDHVLEPLGIETKTADEFLVDQYWLNEARVVSAIQQVADSWKKPPGIYE
                     DVLDRLAASGLLEVTELLRGPGGRFT"
     misc_feature    12831..12849
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: medium, score: 28.74"
                     /tool="antismash"
     gene            12865..14004
                     /locus_tag="EV186_RS30610"
                     /old_locus_tag="EV186_106349"
     CDS             12865..14004
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EV186_RS30610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EV186_106349"
                     /product="siderophore biosynthesis protein"
                     /protein_id="WP_133852939.1"
                     /transl_table=11
                     /translation="MPLYLTALNPTDAVTHGFLPAAARRGLAVVVLTDQPDAHRYDGVE
                     VRRCQVRDAGAIVAAVEGDADGLLSNSDHLQAATAQAAALLGLPGKDWRAAITCKNKLL
                     TRRALAHLDPVAVAPIGDEPSAPKFPAVVKPREGVASEDVVLVNNHEELVKRVAEIRSR
                     RDDPLIVEEYLDGPLRTYETLGGRHFGGFRTSLGPPPFFAETALDWAPELPEPVRAHLE
                     AQLDALGVGFGACHTEFVQQGDRARIVEVNYRLIGDTMDLLCTELLGVDLFDAVIGLHL
                     GEPLPDLPDPVDLQRFARIEYVSATSAGTLVEAPQAQTITAPGVTLTHRRLREPGVAAP
                     LHHTNRDYLSAVHAIGADKQAVHAAVREFVDSNTWRVTG"
     gene            14001..15470
                     /locus_tag="EV186_RS30615"
                     /old_locus_tag="EV186_106350"
     CDS             14001..15470
                     /GO_process="GO:0019290 - siderophore biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF018031.4"
                     /locus_tag="EV186_RS30615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_106350"
                     /product="IucA/IucC family protein"
                     /protein_id="WP_208115862.1"
                     /sec_met_domain="IucA_IucC (E-value: 4.8e-18, bitscore:
                     60.5, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLIARVLTTLLREDHLGMHSDGEPDGDWWRWRHLRLPVEPDGFL
                     ADHRVAKPFLEVRGRRLSTLDAVLAALAPVDDPEAERGWAAFTEECHAAERDTPDLRDE
                     LAPLDPMGFAGLLHYEALAATLEHPVHPAGRARLGLTEAELRAYAPEYRPRFRLRQANG
                     LPVHPLIVARGLVEADELGPEVIPTLSMRTVALADDPGVHLKLPLPTATLGARNTRSIK
                     QGTLADGAEMQRLLAKVLAAEPALADTIVLADESVWVDDPDEYRAALTRRYPSELDGAH
                     LVPLAALAAPDPWGTGTVLDRVAGGDLDAWFDRYLRVLLDFHVALWLRYGIALESHQQN
                     ITLALAGDRIRLVYKDNDGARVDPTRQQAAFADRRMAVADPAELADVFTTITLHLCAAA
                     TVRAAGRDDLFSLIGRRLAEAADRWTDPTDPASVRAAELLRTRVLEADRLPVKAMVTAG
                     TLLPKHRLGCTDINKHYLRTGPNYLRHRSSS"
     misc_feature    15345..15347
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            15467..17227
                     /locus_tag="EV186_RS30620"
                     /old_locus_tag="EV186_106351"
     CDS             15467..17227
                     /GO_process="GO:0019290 - siderophore biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016099.4"
                     /locus_tag="EV186_RS30620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_106351"
                     /product="IucA/IucC family protein"
                     /protein_id="WP_208115863.1"
                     /sec_met_domain="IucA_IucC (E-value: 1.2e-59, bitscore:
                     196.8, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSITLPVLAPPRSAPQRQADLACAHTLLGCVVRELAEPGGHAVAD
                     GPHLVVTLPRTGVRLRARLARTSTVGGHRFTDPVQHKADEWGDLDAATLAELVAAELAA
                     VSGHGNDEFVGQVLASRDTLADLHARRSTSAPRPVGEPASGYLDSEQSLLAGHPRHPAP
                     KWRSGDRAAWRRYAPEYRTAFPLHWLAVRAEAVRDVGHGFDAHARTAWLVGAAFAGHAL
                     VPVHPWQFRLLTDDPVTGLPLAEALADGTIQDLGPVGAPLHPTASVRTLYQPEADLFLK
                     TSLNVRITNCVRRNAEYELTGAVALTEALAEPVRRVGGRWPGFAVLEEPAARSVLLPER
                     YGTQAQRFALLEGLGCIVREGIAAHLERGDQVHLAGALAAAAPDPAGTRTRIADLADGV
                     ADGVTWAREWWRRYLDVLVGPVLALWARHGVVLEPHLQNVLVVTGPDGMPRRVLARDLE
                     GTKLVAGRHRATLAALPPKVAQACAYDEDRAWQRIAYCLFVNHLAELAGALADLAQHSA
                     PGMCRFEDELWDTLGDVLGRLCVELGNPPRLLAMLRGEPLPAKANLLVRWARDADRLAG
                     YVPLRNPFAR"
     cand_cluster    16636..27472
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    16636..27472
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[21635:22472](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      21636..22472
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="2"
     gene            17224..18321
                     /locus_tag="EV186_RS30625"
                     /old_locus_tag="EV186_106352"
     CDS             17224..18321
                     /EC_number="5.1.1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_Arg_deC_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_DAP_Arg_deC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1264: diaminopimelate decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014803.4"
                     /locus_tag="EV186_RS30625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_106352"
                     /product="alanine racemase"
                     /protein_id="WP_133852940.1"
                     /sec_met_domain="Orn_Arg_deC_N (E-value: 7.6e-22, bitscore:
                     72.8, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 4.9e-16,
                     bitscore: 53.8, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIAVPDAVAEAALGVDGPTYLYDLPGLDDHVRAIRTALGPHVEFF
                     HAVKANPDLGVLRTIASHVDGLEVASAGELAHVRKLGTDLLIAFGGPGKTDAELKSTVD
                     LFHVESRYELARLTGATALLRVNLPVPEGPAVLRMGGLPSPFGMDPEDARKAAVEAPPG
                     VRVIGVHAHLVSGVDAEQAAAVAGEVVRWSVDAGLPREVVNVGGGMAVDYLRPDERFDW
                     ARYGRLLRGLAPPGTVLRIEPGRAVSAYHGWYATRVLDVKRSAGSWFAICAGGTHHLRT
                     PAAKGHSQPLAVLPRGSSGPSVDDAPVTFVGQLCTPKDVLARDVVVPRVRVGDVVAFGM
                     AGAYAYNISHTEFLMHPKPAVVHLI"
     gene            18412..19323
                     /locus_tag="EV186_RS30630"
                     /old_locus_tag="EV186_106353"
     CDS             18412..19323
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR04222.1"
                     /locus_tag="EV186_RS30630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_106353"
                     /product="TIGR04222 domain-containing membrane protein"
                     /protein_id="WP_133852941.1"
                     /transl_table=11
                     /translation="MTDLWGIPGPRFIEIYMGLLVAPAIGAVLWRWWQVRRVKPAGPQR
                     SGMTVHHLAYLAGGPKRAAESAVASLLDGERLRVDSTGVLHKVGKAEPADPIERAVFRR
                     AEGARIRSMPVVVADATYELSHDLAKRGLAVPEKSVVLAKRVVAGLYVAIGVLGSVRAW
                     AGSGLGHPVGHLVLLLVVDIAAIAVALWFAERGPDHLITAAGRAMVRDAGRTRRAGAAM
                     VGPAGLILGGAAAWVALDGLQAYPDETVVSALAYTPAATGGGFWGGGGSGYSCSSGAGS
                     SCGGGSSCGGGSSCGGGGGCGG"
     gene            19352..19822
                     /locus_tag="EV186_RS30635"
                     /old_locus_tag="EV186_106354"
     CDS             19352..19822
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EV186_RS30635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EV186_106354"
                     /product="hypothetical protein"
                     /protein_id="WP_133852942.1"
                     /transl_table=11
                     /translation="MAVGVFGLVRLFAGLSVHHPVGYLLLLLLVDVAAIAVSAGLARRT
                     KTDLATEAGRELVREQRRKKEHHGAAAAVSFNGLRAYPDGDLAKALTYSPPPTRRPVRR
                     TSVRSGGVSYMAAGTYDTGSSGSASSCGSSSCGSASSCGGGSSCGGGGGCGG"
     gene            19838..20722
                     /locus_tag="EV186_RS30640"
                     /old_locus_tag="EV186_106355"
     CDS             19838..20722
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR04222.1"
                     /locus_tag="EV186_RS30640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_106355"
                     /product="TIGR04222 domain-containing membrane protein"
                     /protein_id="WP_133852943.1"
                     /transl_table=11
                     /translation="MDTWGIPGPTFLAIFGVLIAVEVVAGLVWKSAQENRSATGTARRL
                     GVYHLAYLAGGRPRVCETAVASLLDAGYLRTNSKGQLSQSSQQAPREPVEMAVFAGAHS
                     RRARELVPVLERPCDALADDLAAAGYLVPRAATKQRRQVILTVAVLVAVLGLARLVSGI
                     AAEKPIGYLIPLFILADAVAIFCFSFSRSARADVTTKAGKDLVNRSRRGDRSVLPLAVG
                     SGVAVAVAVAGLSAFPDEQIVSALGSVPQQTAFSGYSGDGGSSSSSCGSSSSCSGSSCG
                     GGSSCGGGGGCGG"
     gene            20741..21643
                     /locus_tag="EV186_RS30645"
                     /old_locus_tag="EV186_106356"
     CDS             20741..21643
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR04222.1"
                     /locus_tag="EV186_RS30645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_106356"
                     /product="TIGR04222 domain-containing membrane protein"
                     /protein_id="WP_133852944.1"
                     /transl_table=11
                     /translation="MQTWGISGPDWLKLYGVLLVAPFVVGLLWRLVQVMGLGRPSATTS
                     TSLTVHHLAYLAGGRRRMAESAVARLLAAQRVRVSKKGLISVIPGQSLTDKVERTVLGL
                     ASRKRLPQVVGKLGPLATKVNGELAEQGLAVPEKAVQLRRKAVALLSLAFVLLGVVRMG
                     AGVANDRPVGWLVLEVLAGVALMIVAFRLRRRDTTLATMSGRRLLREAKAAHRGRTSTG
                     SAGLVLAGAGAAGAVALGGMALYPDPAIQTALAYVPASFSGGGGSGGGGSNCSSGSSCG
                     GGSSCGGGGGCGGGGGCGG"
     gene            21636..22472
                     /locus_tag="EV186_RS30650"
                     /old_locus_tag="EV186_106357"
     CDS             21636..22472
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020658035.1"
                     /locus_tag="EV186_RS30650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_106357"
                     /product="DUF692 domain-containing protein"
                     /protein_id="WP_243754367.1"
                     /sec_met_domain="DUF692 (E-value: 1.8e-83, bitscore: 274.8,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADLADLADLADLADLGVGIGWRPEIDLTVARLPGVDWVEVVAEN
                     LHVEHLPESLVELRAKGLPVLPHAVSLSLGGADPVDPARVEHLAAVAAALDAPVVSDHV
                     CFVRAGGLDSGHLMPIPRTRDALDVLVANVTTAQSILETPLALENIAALIEWPDAELTE
                     GQFLAELTERTGCALIVDVANLYACARNIGLDIERFLDEIPLERIAYVHVAGGVEHDGA
                     YHDTHAHPVLPQVLDVLARLRDRTQPPGVLLERDDDYPSDSELADELARIRAVVGR"
     gene            22469..22822
                     /locus_tag="EV186_RS30655"
                     /old_locus_tag="EV186_106358"
     CDS             22469..22822
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099301.1"
                     /locus_tag="EV186_RS30655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_106358"
                     /product="hypothetical protein"
                     /protein_id="WP_133852945.1"
                     /transl_table=11
                     /translation="MTREELAARQAQLLWALLADGDPPPGFAAEDLEREAKALWAKRRR
                     VTAMLRPDVAEELGEQYVAAFDRFARSHPKSVTTRARQDADDFAAWAIAEGLLASPPRR
                     PWWKLKDRSSGGR"
     gene            22833..23678
                     /locus_tag="EV186_RS30660"
                     /old_locus_tag="EV186_106359"
     CDS             22833..23678
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010243780.1"
                     /locus_tag="EV186_RS30660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_106359"
                     /product="metallophosphoesterase"
                     /protein_id="WP_133852946.1"
                     /transl_table=11
                     /translation="MTDASLLAVSDLHVSYAENREIVTGLWPDHEGDWLLVAGDIGEKV
                     ADIEWTLGTLADRFAKVIWSPGNHELWSGGSDPVQLKGVARYQHLVEMCRGLGVVTPED
                     PYEVWTGAGGPVTIAPLFTLYDYSWRPAGTRTKAEGLAAAHEAGIVCTDEYFLDPSPYP
                     TRDDWCRARVAETERRLAAVEGPTVLVNHWPLRREPTLVLRYPVFAQWCGTDLTADWHT
                     RFNAAAMVYGHLHIPRSTVYDGVPFEEVSVGYPREWQARRKRERWVRTILPAAQQVERA
                     "
     gene            23675..24322
                     /locus_tag="EV186_RS30665"
                     /old_locus_tag="EV186_106360"
     CDS             23675..24322
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA]"
                     /NRPS_PKS="Domain: ACPS (101-162). E-value: 3.7e-17. Score:
                     54.4. Matches aSDomain:
                     nrpspksdomains_EV186_RS30665_ACPS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1060: 4'-phosphopantetheinyl transferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015803992.1"
                     /locus_tag="EV186_RS30665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_106360"
                     /product="4'-phosphopantetheinyl transferase superfamily
                     protein"
                     /protein_id="WP_133852947.1"
                     /transl_table=11
                     /translation="MIDRILPAKAVAVEAFEDPPEAVLLPVEAAAVAKAVANRRREFTT
                     VRHCARLAMAKLGVPYVPLVPGERGAPSWPSTVVGSMTHCAGYRAAVVAHATELRSVGV
                     DAEPHGPLPDGVLDAVSLPAERDHLAGLPSSVHWDRLLFSAKESVYKAWFPITQRWLGF
                     EEASLEFATDGTFSARLLVPGPVLDGVELRGFEGRWLVEDGFVLTAIAVPFA"
     aSDomain        23978..24160
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EV186_RS30665_ACPS.1"
                     /evalue="3.70E-17"
                     /label="EV186_RS30665_ACPS.1"
                     /locus_tag="EV186_RS30665"
                     /protein_end="162"
                     /protein_start="101"
                     /score="54.4"
                     /tool="antismash"
                     /translation="VGVDAEPHGPLPDGVLDAVSLPAERDHLAGLPSSVHWDRLLFSAK
                     ESVYKAWFPITQRWLG"
     gene            complement(24476..25210)
                     /locus_tag="EV186_RS30670"
                     /old_locus_tag="EV186_106361"
     CDS             complement(24476..25210)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF013245.4"
                     /locus_tag="EV186_RS30670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_106361"
                     /product="ABC transporter permease"
                     /protein_id="WP_133852948.1"
                     /transl_table=11
                     /translation="MTGYLTLEIKRMLRTPRFVLFAIALPTLLYLLQSGLYKDESVPGT
                     DVKYKAYLLCGLAAYGAFVSALSTGIRIAAERSGGWQAQLRLTPLSPKAYLLSKVVVSM
                     IVALPAPIIVAMAGGFIENVHLSAGAWVQLTLGTWLASLPFAVLGVLLGLLASADSVQI
                     YTAGVQLGFGFLSGLLIPLTGFPSWVASAVKAIPSYWLADIGHGALLGNNNTALAVLVL
                     GAWTVALSALVVFSYRREAALA"
     gene            complement(25207..26205)
                     /locus_tag="EV186_RS30675"
                     /old_locus_tag="EV186_106362"
     CDS             complement(25207..26205)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003094876.1"
                     /locus_tag="EV186_RS30675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_106362"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_133852949.1"
                     /transl_table=11
                     /translation="MPVQTTPPRTTQAVTIRDLRKNYETKTGTVAAVRGVDLAIGTGEV
                     VAVLGPNGAGKSTTVATILGLTQPSAGTVEVFGKTPRDAVTEGLVGAMLQQGNLLEDVT
                     VAEVIGMIAGLHKHPMPAEQAMRMAGVTDIADRYCTKLSGGQRQRVRFAMALVGDPRLL
                     VLDEPTAAMDVGSRRDFWQAMRSFTDTGRTVLFATHYLDEAEEFADRVVLLRDGRVVAD
                     GTVAEVRGSVTGSVLRAVVPGATLADLLRLPGVTGGELRGDRAELSCDDSDTALRALLV
                     EHPLAHHFQITAMGLEEAFLSLTSTEEPLAGSSISTEEPLAGSSISTEESR"
     gene            26314..27495
                     /locus_tag="EV186_RS30680"
                     /old_locus_tag="EV186_106363"
     CDS             26314..27495
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF019350.4"
                     /locus_tag="EV186_RS30680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_106363"
                     /product="histidine kinase"
                     /protein_id="WP_133852950.1"
                     /transl_table=11
                     /translation="MQGQLSEDAERAARLRAYEFTANQWPAWGFAGRDRDRKQNAVVRN
                     LFAPVAFMFFMFAAVRDDLAGPHPIVQRVLLAIVATVYALSFVAVLVARMRVQASHRTR
                     ALIVAWMLLLGGLLPVVSMDAKDFPMITYAMVITVLVVPLRYSRPIGAVVIGLQMLITW
                     LADGAVDWSGTWTLVLVTVSVTSLLIVGNTIQSLRDANSMIADLAVAEERSRFARDLHD
                     LLGHSLTTITVKSGLARRVLETGAATERAISEVRDVEELSRKALVEVRAAVSGYHQISL
                     AAELVNAKAALRAAGIEAVLPGGVEELRSSLREQFAWVVREGVTNVVKHSGASRCEVRL
                     GESWLEVRDNGRAGSGSPSAGNGLRGLRDRLAASGSSLTWERVDGWFVLRAAA"
     gene            27533..28168
                     /locus_tag="EV186_RS30685"
                     /old_locus_tag="EV186_106364"
     CDS             27533..28168
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF025605.4"
                     /locus_tag="EV186_RS30685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_106364"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_133852951.1"
                     /transl_table=11
                     /translation="MATSTEPARRGRPPSSQKRAAILEAATSVFLDNGYDRTNLDDVAA
                     VAGVSKQTVYRHFTDKKSLFMAVVEAAREQQLRPADAVATVLDPDDLLGSLTRFGERML
                     TVVLSKRVAALRRVMIGELSRIPELREMWAAGAPTAIATVLITELVALTERGVLDVPDP
                     VAAVENYFGLLSFRGMNNTAYGVTELSAKDRKRIAESAADLFVRAYSR"
     gene            complement(28574..29611)
                     /locus_tag="EV186_RS30695"
                     /old_locus_tag="EV186_106365"
     CDS             complement(28574..29611)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014741.4"
                     /locus_tag="EV186_RS30695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_106365"
                     /product="DUF222 domain-containing protein"
                     /protein_id="WP_166659398.1"
                     /transl_table=11
                     /translation="MELGELNSTVAQLRRLELKLLDDISHLEWKESGYPQLWRFLQDVL
                     HLTAPEAKRLEHHVELLCPKVGITGQSIPPRLPAARAAMTAGEISGAHVDKIATAVELV
                     PVEHAEQVDVDMTELAREFNPTQLIHLGKRIVDALNPDGRKPVEPTVVDAQNTLDLYEH
                     RDGSLSGQFRLGAEDASVLRALLSPLAKPQPQDDRILSERQGDALAEIIGFAADSGRAP
                     AEGGERPHIAVTVSLETLQTRIGRAMLDDGRTLAPEQARRVACEAKLIPIVLDGKSQPL
                     DIGEPADWPINDCAEPSPSATKAAPHPAAREHRINVTRITSNIGPTADQQRSIIWYWCA
                     LIIIG"
     misc_feature    complement(29633..29648)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 20.99"
                     /tool="antismash"
     misc_feature    29663..29677
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.12"
                     /tool="antismash"
     gene            complement(29784..30425)
                     /locus_tag="EV186_RS30700"
                     /old_locus_tag="EV186_106366"
     CDS             complement(29784..30425)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013672530.1"
                     /locus_tag="EV186_RS30700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_106366"
                     /product="response regulator transcription factor"
                     /protein_id="WP_243754368.1"
                     /transl_table=11
                     /translation="MTDIRVLVVDDQQLVREGLVALLGLLDGVTVVGHAGDGAEAVRLA
                     AETVPQVVLMDLRMPRMDGVAATAEIVKRHPSIGVLVLSTYADDESIGSALRAGARGYL
                     TKDAGRAEILAAVRSCAVGQSTFDPVVSARLASALTGTRPEPPPDHLTAREAEVLGLIG
                     GGSSNTEIAASLFISETTVKTHINNAFAKIGAKNRADAVRYALRHGLAQA"
     gene            30493..30753
                     /locus_tag="EV186_RS40240"
                     /old_locus_tag="EV186_106367"
     CDS             30493..30753
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EV186_RS40240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EV186_106367"
                     /product="hypothetical protein"
                     /protein_id="WP_243754369.1"
                     /transl_table=11
                     /translation="MEAHDVMTLLLVRFAIVAGGIALLAVAAFTVLVVLKRNGKQVDAR
                     RYVEPVVRSWAQSPSRRRRRGGAAKFATRTVLNHLDREDRR"
     misc_feature    complement(31025..31038)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.84"
                     /tool="antismash"
ORIGIN
        1 cttctgctcg tcggtggggg tgatgtcgaa gaggtcctgc tccggggcct tgggcagccg
       61 cgcgggctgg ccgagcttgc tcgccgcggt gaacgtgcgg ctcgtcgccg ccgccgtccg
      121 gaacccggcg cgcgtggcct ggtaaagccc gcgctcgacc ggtttgcgca ggccaaggcg
      181 gtcgagcagg ccgagcccgg ccacccggtt gagcaccccc agtgccgcgc ccatcgggtc
      241 gcgcttctcc ttcgccacga cggctccccg ttcttacccg tgagtaggaa tcggaaccta
      301 ctctagagta gtaaacgagc cgtcgccaat caggttgcga gcagtggggg cttcttgtgc
      361 gtccacggcc gggctgtttc gaaggcgagg cacgcggtga gcacgcgggc gtcggcgtgg
      421 cgggggccga ccacctgcat gccgatcggc agcccggccg cggtgaaccc gcacggcacc
      481 gaagccgcgg gctgctgggt catgttgaac gggtaggtga acggcgtcca gctggtccag
      541 cggttgcggg accacccggc gggcacctcg acgccggctt cgaacgcggg gatcggcagg
      601 gtcggcgtga ccagcaggtc gtagcggcgg tggaactcgc ccatgatccg gccgagttcc
      661 atccgggtag acgtggccgc gaggtagtcc agggcgctgt aaccccggcc ctgctcgacg
      721 atctccatca gcccggggtc cacatcggac gttgccggga acgcggccac cgacgcggcc
      781 gcaccggaga accacagcgt ttcgaaggcg tccaccgggt cggtgaaccc cgggtccacc
      841 tcgtcgacct gcgcgccgag ctcgcggaac acccgcaccg cggcggcgac cgcggccgcc
      901 acctccgggt tcacccgcac gtagcccagc gtcgggctga acgcgatccg catccccgcg
      961 accccgtcgg ccagccgctt ggccaccggc tcggccggcg ggcccgccga ccagtcgcgg
     1021 gcatcggcgc cggacaggac gtccagcatc agcgcgccat cggtgaccgt gcgggtgatc
     1081 ggcccgacgt gagcgagcgt gccgaacgcg ctcgccggga agagcgggac ccggccgtag
     1141 gtcggcttgt gcgcgaacac gccggagaac ccggcgggga tgcgcaccga gccaccaccg
     1201 tccgtgccga cggcgagcgg gcccatgccc agcgccaccg cggccgccgc gccgccgctg
     1261 gagccgccgg ccgtcttcgc cggatcccac ggattggtgg tgacgccgct gaccgggctg
     1321 tcggtcacgc ccttccagcc cagctcgggc gtggtggtct tgccgacgag cacggcgccg
     1381 tgctcgcgca gccgggccac ggcgggcgcg tcgaccttcc actcctggcc gggatcgatc
     1441 gtcttggagc cgcgcagggt cggccagccg tcggtgagca ggatgtcctt gatggacgtc
     1501 ggcacgccgt cgagcagccc gcgcggctcg cccttgcgcc agcgggccgc cgattcggcc
     1561 gcctgggcaa gcgcgcgttc gccgtccacc agcaggtacg cgttcaccgc cgggttgagc
     1621 tgctcgatgc gcgccagcgt gtcctcgcag gcttgcacgg gggacaactc cccggaccgg
     1681 taggccgcga gcagttcggt cgcggtcagg tcagcggtcg acatgggact cctcggactg
     1741 cttcgacggc acgtacccac gccgcttgtc cacgacgttg cgcagcgggc gatcttgggt
     1801 gaagcgtgcc aggttgtcgg cgaagagcgc caccagctcc tcgcgccagc ccagcacgtc
     1861 gccggacatg tgcggcgaca cgatgacgtt cggcattgtc cacagtggag agtcggtggg
     1921 cagcggctcg acgtcgaaca cgtcgagggc cgcgcccgcg agttcgcccg ctgccagggc
     1981 ggccaccagc gcgtcggcca ccaccagcgg gccgcgggcg acgttgacca ggcgcgcggt
     2041 gttcggcagc gcggccagcg ccgtggcgtc gaccatgccc cgggtctgtt cggtgagcgg
     2101 cgcggcgagc acgaggaaat cggtgtccgg caaggcgttc cggtactccg acatgtccag
     2161 cacgcgcccg aagtccggat cgccggcgcg agccgtgcgg ccgacccccg tcaccaccag
     2221 gcccgcggcg gtcagcaggc gcgcggtggc ccgcccgatc ggcccggtgc ccacgaccag
     2281 ggcccgcttg ccgccgatcc gctcggtctc gcggtgcacc cacctgcgtt cgccttgcgc
     2341 ccgcaaggtc gtcggcaagt ccttggccag cgcgaggatc gcgccgagca cgtactcggc
     2401 catcggctgg tcgaagacac cgcgcgagtt ggtcaccacg atctcgccct cgagcacgcc
     2461 ggggaccagc acgtggtcga cgccggcgct cgccgcgtgg acccagcgca gggcgctcgc
     2521 gccggcccag gcgtcggcca gcgcgcgcga gcggaagtcc cagacgaaca ggacctcggc
     2581 gccggtcagg gcgtcggcga ggctctcacc ggtgcagtag cggaccggga aatcgcgctc
     2641 gatcccttgc atggcaggcg gtttgtccgc gtcgtgcagg accgtgacgg tcggcggcat
     2701 ggaggtccga tcgaagtcga ggaagtattg acacgctagg aacggctcgt atgattgtca
     2761 acaatcggcg cggacggagc agcccgcgag aggacggcag cgtgctgcaa gaccgtcacg
     2821 acggatccca aggcgcactc ccaaagcaaa caaacactcg ggtgggctgc cttcgctcac
     2881 ccctgagctt gcggggtgaa tatgtctcgg ctcatgaaga tctccttggc gaagcgtggc
     2941 gtgtcctgtg tggcgcgcct gctcgacaag gacgcgccac ggacctgcga cgccgtgtgg
     3001 aatgcgctgc cgctcggcgg cgacgcctac cacgcgaaat acgcccgcaa cgaggtctac
     3061 acgatggtcg agcggttcgc cgagccggtc ggccaggaga acccgacggt cacgcccatc
     3121 cccggtgacg tggtcttctt cgacttcaac ggcggcatgc tcgaccgcgc gttcaaggag
     3181 gagaagggga tcgaccagct gcccggcgtg atcgacctgg cgatcttcta cgggcgaaac
     3241 aacctgctgc tcaacggcga tgtcggctgg gtgatcggca acgtgtacgg caccatcgtc
     3301 gaaggcctcg agcagatggc cgaggcctgc aacgacgtct ggcgggcggg cgcgatcggc
     3361 gagcggctcg tgtacgaacg cctcgacggc tgagcgccgt catgacgatc gacaacgtgg
     3421 agctcatcgg ccctgagctg gtgacccagc acgggatcgg cgtcgtggcg ccgttcgact
     3481 tcgcgctcga ccgcgagctc tggcgctgga cgccggacaa cgtctccctg tacatgacca
     3541 ggctgccgtt cgtgccggtc ccggtgacga tcgagatggc atccgaactg tccgatccgg
     3601 accgggtgag ccgggcgacc aaggacgtcc tggccccgga accgctcgcg gtggcctacg
     3661 cgtgcgcgtc cggcagcttc gtgcacggca tgctcggcga gcggctgctg gccaagagca
     3721 tggtggacgc gggcgcgccc gccgcgacga ccacgtccgg tgggctggtc gaggcgttgg
     3781 cgctgctcgg tctgcgccgg atcgcggtgg tgacgccgta catcgacagc gtgacccagc
     3841 ggctgctggc gttcctcggc gagcacggga tcgagtcggt cgacagcatc gggctcggcc
     3901 tgctcagcca catctggaag gtcgggtacg ccgaggtcgt gcaggccgtg cgcacggtcg
     3961 accggcccga cgccgaagcg gtgttcatca gctgcaccaa tgtgccgacc tacgacatca
     4021 tcgcgccact cgagcggatg ctcggcaagc cggtgctcac cgcgaaccag gtgacgatgt
     4081 ggtcggcgct gcgggcggcc ggcttcggcg cgatcgccgc ggaacagcgc ctcgtccagg
     4141 ccacgacccc cacagccgcg tgatcgacgt agcgaacccc cacggcttcg gccgaggcca
     4201 tatgattgtc gacaatctca agggagcgtc cccgtgacaa accacaacgg cctcggcccg
     4261 gcctgtctcg tggaggtcgg tcacgaccgg agcgaggcag gccatgaagg ggccgaggcc
     4321 cgcgcgagcg gagagagcgc aatcccacac ggcgccgagg cccgcccgaa cggagagagg
     4381 gccaacaaca cggcgcccac cattggtttc ctgtaccccg gctacagcgc cgaggacgac
     4441 tacccggcca tcgaggcgat gctgggcgac gtccggctgc cggtggtgca caccttgatg
     4501 cgcgaggacg cgcaccgggt ggacgccctg ctcgacatcg gcggcaacga cgtgctgagc
     4561 gtgggcgcgg tgaagctgcg tcagctcggc gtcgacgcgg ccatgtgggc gtgcacgagc
     4621 ggcagcttcg tcttcggctg ggacggcgcg tccgagcagg tcgacggcgt gcgtgaggcg
     4681 gcgggcgtgc cggcgtccag cacgtcgttc gccttcgtcc acgcggcgcg ggcgctcggt
     4741 gtgggcaagg tggcggtggc ggcgacctac ccgaaggacg tggccgaccg attcgtggaa
     4801 ttccttgcgg gcgcgggcat cgaggtcgtc tcgctgtcgt gccgggggat cgtgaccgcg
     4861 gccgaggtgg gcacgctggg gcgcgaggac gtgctcgcgt tcgtcacggc caacgaccac
     4921 ccggacgccg aggcggtgct ggtgccggac acggcgctgc acagcgtgcg ctggctcgac
     4981 gacctcgaag cggcactcgg caagccggtg ctgaccgcga accaggtgac cgtgtgggcc
     5041 ggcctgcgcc tggccggtca cttcgagccg agaaccggtc tcggctcgct cttccgggcc
     5101 ggcgtggccc aggtgaactg aacagaagga tcgtgcgatg agcgaactcg gcgagctgga
     5161 accgatcacc cgcaggtcca ccgccgcgat catcgccgac cagctccgct cggcgatcat
     5221 gtacggctcg ctgccgccgg gctcccagct gggcgaggcc gacctcgcgg ccaagcttgg
     5281 cgtgagccgc gggccgctgc gcgaggccat gcagcggctc gtccaggaag gcctgttgcg
     5341 cagtgagcgg caccgggggc tgttcgtgat cgacatggac gccgccgacg tgcgggacgt
     5401 ctaccaggcc cggctcgcga tcgagcgcgc ggcgtgccag ctggtcatgc agggcaaccg
     5461 gggcgaggcg ctggcgacgt tgtcggccgc gctggagggg attcttgagg ccgcggcctc
     5521 ccgtgaccga attgcaatga gcgatgcgga ccaagccttc caccaagccc tggtggcgtg
     5581 ctcgggcaac tcgcggttgg tgcggatggc acaaaccctg ctggtagaga cccggatgtg
     5641 cctctcggcg ttgcaggcgc actaccccga accggacgaa ctcgtcgccg aacaccgtgc
     5701 gttggtcgac gcgatcgcag atggggacga aagactcttg ttggagctga tcgagcgcca
     5761 catgctcgat tccattgatc gactcaaccc ctagccgggt aacggattaa tcgaggtagc
     5821 ggcccattcg ggaggtttct caccgacaag gtgccgtctc ggtcactccg aaacatgaca
     5881 caaacgtccg gccaggagca tgttgtgacc actttgcgtg atgggtgggc agggacgaaa
     5941 gtcccccaga tgcagcaaaa agacccctag tcgcggattg gtccatgctg tagcgtcacg
     6001 cagcgtcaag gaacacggca cgaacggccc cggccgtacc ggcacacccc cgttgccttg
     6061 attttatgcg ccgcccccgg gaaccatccg gcggtgctcc cggttggtgc gtgcgcaggg
     6121 agaaacacgt gacatctggc ccggtcgttc aaaattcaat cgcccctgac ctgaagggcc
     6181 ccgacttcca caaagtggtc gtcgacgcac aggcgggcga cagggaggct attgcgacgt
     6241 tgttcgtgcg gttgcagccg gcagtgcagc ggtactgccg agccaggatc ggccgctcgg
     6301 gttcgtcgta ctcctcggcg gacgacgtga cgcaagagat ttgcctgggt gtgcttgggg
     6361 cgctgaagaa gttcgccgac gacccgtcgt cgttcttgcc cttcgtgtac ggcatcgcgt
     6421 cgcacaaggt cgccgaccac taccgcaaag caggtcgtga ccgcacggac ccggtcgccg
     6481 acatgcccga cctcgtcgac cgcaacgtgg gtcccgagca gtacgcgctg cgcggtgacc
     6541 tgcgtgccaa gttgctgcaa ctcatggacc ggctcgcgcc gcgccagcag gaaatcctgc
     6601 ggatgcggtt gatcgtcggt ctgtcggccc aggagaccgc gacggccatc ggcctgaccg
     6661 cgaccgcggt gcgcgtcacc cagcaccgcg cgttgaacaa gctccgcgaa ctggccgcgg
     6721 gcctggacct ccgctaaaca gcgacacctc aacagaccgg cgcgtcggca cccccgacgc
     6781 gccggttttg tttcgccatc tttccctcac cccgcacccc acccattcat tccacatgaa
     6841 tacctccttc catcccgcaa attcccagct ctccccacac ctcccgctcc gccctcacgg
     6901 gaactagccc gctaaatccc gctaaaggga cgggggttgc gttagtggca agagtgcgtg
     6961 ggcgagggtc ggacctcttc attcattccg catgcatgcg tgggtggtgg cgggaaactg
     7021 ctggtcagcg gatcggcggg ctgggaagtg cgggggaatt agcctgctga accccttgaa
     7081 gcgtgaggtg ggggttgtta cgaggggtgt ggggaagagt tggggtcaga gggtggcgag
     7141 gcggcgggtg aggaagtcgc gttcggccgg gttggtggtg agggcgaggg cctcgcggta
     7201 ggcggcggcg gcttcttcgg gacggcccag gcggcgcagg aggtcggcgc gggtggcggg
     7261 caggtagtgg tagtcggcca ggcggggatc gtcggccagt tcggtgagct cggccagggc
     7321 gcgttcgggg ccttgcgcca tggacaacgc cgcgatgcgg ttcaaggcga ccaccgggga
     7381 ctgccagacc gtggccagca cgtcgtagag cccgaccact tgctcccagt cggtctcctc
     7441 gtagctcggc gcctccgcgt gcagcgccgc gatcgccgcc tgcacggcga accggccggg
     7501 acgcccgccg cgcaacgcgt cgaagaccag ttcgcggccc tcctcgatgg cgacgcggtc
     7561 ccagctggat ctgtcctgtt cggacagcag cagcatccgg ccgccggcgt cggtgcgcga
     7621 accgcggcgg gcgtcgagga ggaccaacag ggcgagcagg cccgtcgcct cgcgctcgtc
     7681 gggcatcagc gcgtggacca ggcgggcgag gtcgatcgcg agcgccgtca ggtcggcgcg
     7741 gaccaatccc tcgccccgcg gcgccgtgtg cccggtggtg tagaccaggt ggaccacggt
     7801 gagcacggcg tcgagccggt cgggcagctc cgccgggccg ggtacccgga acgggatgcc
     7861 cgcgcccgtg atcttcttct tcgcccgggt cacgcgcgcg gccatggtcg gctcggacac
     7921 caggaacgcg tcggcgatct ccccggtggt caggccgcac aacaaccgca acgtcaacgc
     7981 cacctgtgcc tcacgcgcga gcgctgggtg gcaacaggtg aagatcatcc gcagccggtc
     8041 gtccggcacg gcttcgggcc ggggcggcgg gtcgtcggac ggcggttcga ccagcagcgg
     8101 cagcttcgcg cgcagggtgc tcgaccggcg catcgcgtcc atcacgcgcc ggcgcgccac
     8161 ggtggtcagc cacgcggcgg ggttgcccgg caccccttgc cgggtccaca cctcgagcgc
     8221 agcgacgtac gcgtcctgca cgcactcctc cgcgaggtcg aggtcgccgg cgacgcgcac
     8281 cgtcgcggcg agcacgaagg cccactcgcg ccggtgcgcg tccgcgaccg cgtcggccgg
     8341 ttcgatcact cgaagaccat gaccggccgc acctccacgc caccgaactc cgccgggcac
     8401 agcttgccga cggcgatggc ggtgtcgagg tcgggcgcct cgatcacgta gtagccgccg
     8461 agcgcctcct tggtctccac gaacgggccg tcggtgacga cgtcgccgcg gatggtggtg
     8521 gccgtcgggg tcggctgcaa cgcctcaccg cccaggagct tggcgccgtg ctcgggcacc
     8581 tgctcggtga accggctgtg cgcctgcatg acccgctcga acacctcggg cgtcgcgttg
     8641 gcgtacgact cttcgttctc gtagatcagg atcaggtact gggccatgtc gatctcctag
     8701 ttttcggagg tccattcgaa cacccctccg tcggatgggg tcggtgggaa tcgacagcct
     8761 gttccaagat tttttcagcg agtccactct ggagagcggc cgagcagtcc gatgaggcgt
     8821 tggtgcgggg aagcggtgtc cgcaacgtcc actcggtacg cgaacgccgc gcccggcccg
     8881 cgcgacggcg gttcgttcgg gatccgctcc gcgatcgcca tgcccgcctc ggtcagcgcc
     8941 gggtccggtt cgctgagccg atccggccgg cccagcgccc gcgctacgtc ccagccgtgc
     9001 gccaggtagt ccacgaagtg gaacccgacc gcgatcttgc ccgggaccgc acgcccgaac
     9061 tccgcgaggt acacctcgtc gtcgatggac cggaacgctt cggtcgcctc ggccgccgat
     9121 gcgacgaacg ccgcgtgcgg atcttcctcc agccgtcgcg gctcccagtc cgatttgtcc
     9181 cgcgcaccac cggaagcggc cgccgcgaac ccccttgttc tgcgcgacca ggtgctcgat
     9241 caactccatc aggttccacg caccgcacgg cgtcggtgcg gaccaatccg cgggccgcgc
     9301 ctcggcgatc agccccgcgg tccacgccat ggccagccgg tccaactcga cgatgtcgct
     9361 cacgatgtca acctagccgc gtggtcgatc ccttttggct caaggcgaca cgttcgcacc
     9421 gcggctagtc tggggagact gcccgcgact ggtgaggagg atccgcatgg cgatcatgcc
     9481 ggtcaccgac tcgatgttcc tgctcgcgga gtcccgcgag caccccatgc acgtgggtgg
     9541 cctgcaactg tggaaaccgc ccgccgacgc gggtccggac tacctcgccg agctgcacca
     9601 ccggttgctg gccaccgagg tgcgctcgct gttccggcgc cggttgcgcg ggccgatcgg
     9661 cctcggccag gcctggcgca tcgacgacga catggacctc gagtaccaca tccggctctc
     9721 cgcgttgccg cgtccgggcc gggtgcgtga gctgctcgaa ctggccggcc ggctgcacgg
     9781 ttcgctgctc gaccggcacc gcccgctctg ggagtaccac ctcatcgagg gcatgaccga
     9841 cgggcggttc gccagctaca ccaaggtgca ccactcgctg ctcgacggcg tcagcgcgct
     9901 gcggctgctg gcgaagtcgc tgtccaccga cccggacgca cgcgagctgc tgccgccgtg
     9961 gggcgagccg ccggccagcg agaagaaggg cccgcgcgct aacggcggtc cactggccgg
    10021 gatccgcggc gcggccaagg cggtcggcga gctcgccggg ctcgcgcccg cgttgtggca
    10081 gacggccaac gacctgttcc gcgagcagag cgccagcacg ctcgcctcgc ccgcgccgcg
    10141 ttcgatgctg aacgtgccga tcaccggcgc ccgccggttc gccgccgacc agtgggacat
    10201 ggaccggatc aggaaggtca gcaaggccgc gggggccacg ctcaacgacg tcatgctggc
    10261 gatgtgctcg ggggcgctgc gccgctacct cttgtcctat gacgcgttgc ccgagcggcc
    10321 gctggtcgcc ggcgttcccg tgtcgctgcg ggcccgcaag aaggacagcg gcgacagcgg
    10381 caacgcggtc ggcctgatcc tgtgcaacct cgcgaccgac caggccgacc cggccacccg
    10441 cctcgccgag atccacgcgt cgatgaccag gggcaaggag ttctacgcgg ggatgagccc
    10501 gctgcagatc accgcgttgt ccgcgttgcc gctgatcccg ctcgcggtcg gcgtgctgcc
    10561 cggcggcacc aaggtgatga gcccgcggtt caacgtcctg atctccaacg tgcccggccc
    10621 gccgcggcgg ctctactgga acggcgccga gctcgacggg atctacccgg tgtccattcc
    10681 gtacgaaggc caggcgctca acatcaccgt taccagctac gcgggccggc tggccttcgg
    10741 gctgaccggc tgccgtcgca cggtgccgca cctgcagcgg ctgctcggct acctggagga
    10801 ctcgctgacc gagctggaga aggccacgtc cggcgtgtag ggcgagggat cagccgctct
    10861 tgcggcggaa ctggcgcttg ccgccggccc ggccgtggga gtcgtgcacc ttggacgagg
    10921 cgtccgcgtg ggcggcgcgc gccgtggtgg cggcctgctt gcgctcgagg gcttcgcgga
    10981 acttgcgctt cacgtcctcg gtctcggggg tggcctcgtc gttctcgttg gcttccggtg
    11041 cgtccgacat ggccccaacc tcctgtgaac cgacgtgtgc gatgcgagcg tggcacgaag
    11101 atcggtgccg cgcgaactca tttcatccta tgttgggccc atgacctacc tcggtgacac
    11161 cggcgagatc agcgccctgt accggccggc ggccgagatc cagtccgtgg tacgcccctt
    11221 gagcacgtcg acgttcgtcg cgcccggctc ggtgaccaac gggcagtacg gcttgttccg
    11281 ctgggacatg cgcccggagt ccgggggccc ggacgcgcac ttccacaaga ccttctccga
    11341 agccttctac gtcctcgacg gcaccgtggg cctgttcaac ggcgacaagt gggtggacgc
    11401 caaggccggt gactacctgt atgtccccga gggcggcgtg cacgcgttcc acaacaagtc
    11461 ggacgcggcg gcgtcgatgc tgatcctgtt cgcgccgggc gcgccgcggg agaagtactt
    11521 catcgagctg gcggagatcg cggagagcgg ccgcaagctg accgacgagg agtggctcga
    11581 actctgggcc cgccacgacc agtacccggc ttgacgctga aggctgtcgc cagtcggttg
    11641 cggatattgc gcttattgcg gataatgcgt ttaggccctc aatcgatcgc gaggctgtgg
    11701 gagacgccat gaccaggttt gatgctgcgg cgctgacacc ggaccagcgg gatgttcgga
    11761 cggcacacga cgcgttgccg cacatcaagg cgtacctcgc caggcatcac gcgcgcgacg
    11821 tcgtgcggct cgtcgccgat ggcggggacg agcccctcga ggttccgcga gccgcgatcg
    11881 agttgctggc tcgcatcctg acgcacatgg cggcaggcca gggcgtgtcc atcgttccgg
    11941 ccaacgccga gctgacgacc cagcaggctg cggcgatgct gaacgtctca cgtcccttct
    12001 taatcaagct gctgaacgat gggaagatcg agtaccgcac ggtcgggacg catcgacggg
    12061 tgttggcgga gtcgctgcgt gactacatgc gcgcggaagc tcagcgcatg agcgatgtcg
    12121 caagcgaact gacggctctg aatcaggaga tggggctgac gtaggccgtg gcgttcgttg
    12181 ttctttacga tgccaacgtc ctgtatccgt caacactgcg cgatgtgctg atccgcattg
    12241 cgcagggtgg attggtgcaa gcgaaatgga cagaccgcat cctcgatgag acgttctcca
    12301 gcatcaagcg gaatcatcca gacatcgaca ttgccaagct ggatcgcact cgtgtgttga
    12361 tgaaccaggc ggtgctcgac tgcctggtca ccggttacga gccgctggag catgccttcg
    12421 agctgccgga tcccgacgac aggcacgtgc tcgcggctgc cgtcaagagc caagctcaag
    12481 tcattgtcac ggagaacatc cgtgactttc cagaccacgt cctggagccg ctgggaatcg
    12541 agaccaagac cgctgacgaa ttcttggtgg atcaatactg gctcaacgaa gctcgtgttg
    12601 tcagtgcgat ccagcaggtg gcggattcct ggaagaagcc ccctggcatc tacgaggatg
    12661 ttctcgatcg gctggcggcc tctggcttgc tcgaagtgac agagctcctg cgtggaccgg
    12721 gcggtcgatt cacgtgacgg cggggtccgg ggccggcggt gacgggctgt cggggccggc
    12781 ttgatcactc catggtgtgc cctggcttga cggcgttgcc ggagagccag ttaggtaagg
    12841 ctcaccaatt tcgttggagt gccggtgccg ctgtacttga ctgcgttgaa cccgaccgac
    12901 gcggtgacgc acgggttcct gcctgccgcg gcccggcggg ggctcgcggt cgtggtgctc
    12961 accgaccagc cggacgccca ccgctacgac ggtgtcgagg tgcggcgctg ccaggtgcgg
    13021 gacgcgggcg ccatcgtggc ggccgttgag ggtgacgccg acgggttgct tagcaacagc
    13081 gaccacctcc aggccgcgac cgcgcaggcc gcggcgctgc tgggcttgcc gggcaaggac
    13141 tggcgggcgg ccatcacgtg caagaacaag ctgctgacca ggcgcgcgct ggcccacctc
    13201 gacccggtcg cggtcgcgcc gatcggcgac gagccgagcg cgccgaagtt ccccgccgtg
    13261 gtcaagccgc gggaaggggt ggccagcgaa gacgtcgtgc tggtgaacaa ccacgaggaa
    13321 ctggtcaagc gggtcgcgga gatccggtcg cgccgggacg atccgctgat cgtcgaggag
    13381 tacctcgacg ggccgctgcg cacctacgaa accctcggcg gccgccactt cggcgggttc
    13441 cggaccagcc tcggaccgcc gccgttcttc gccgagacgg cgctggactg ggcgcccgag
    13501 ctgcccgagc ccgtgcgggc ccacctggaa gcgcagctgg acgcgctggg cgtcgggttc
    13561 ggtgcctgcc acacggaatt cgtccagcag ggcgatcgcg cacgcatcgt cgaggtcaac
    13621 taccggctga tcggcgacac catggacctg ctctgcaccg agctgctcgg cgtcgacctg
    13681 ttcgacgcgg tgatcgggtt gcacctcggc gagccgcttc ccgatctgcc ggatcccgtt
    13741 gacctgcaac ggttcgcacg catcgagtac gtcagcgcca cgagcgcggg cacgctggtc
    13801 gaagcgccgc aagctcagac gatcaccgcg cccggcgtca cgctcaccca ccgccgcctg
    13861 cgcgagcccg gcgtcgccgc gcccctgcac cacaccaacc gcgactacct ctccgccgtg
    13921 cacgccatcg gcgccgacaa gcaagccgtg cacgcggccg tgcgcgagtt cgtcgacagc
    13981 aacacctggc gggtgaccgg gtgacgctga tcgcgcgcgt gctgaccaca ctgctgcgcg
    14041 aggaccacct cggcatgcac agcgacggcg aacccgacgg cgactggtgg cgctggcggc
    14101 acctgcgcct gcccgtcgag ccggacgggt tcctcgccga tcaccgggtg gccaagccgt
    14161 tcctcgaagt ccgcggccgt cgattgtcca cactggacgc ggtgctcgcg gcgctcgcgc
    14221 cggtcgacga cccggaagcc gaacggggct gggccgcgtt caccgaggag tgccacgccg
    14281 ccgagcgtga caccccggac ctgcgcgacg agctcgcccc gctcgacccc atgggcttcg
    14341 ccgggttgct gcactacgag gcgctggccg cgaccctgga acaccccgtc cacccggccg
    14401 gtcgcgcccg gctcggcctg accgaggccg aactgcgcgc ctacgcaccc gagtaccgcc
    14461 cacgcttccg gctccgccaa gcgaatggcc tcccagtgca cccgctgatc gtcgcgcgcg
    14521 gcttggtcga ggcggacgaa ctgggtcccg aggtcatccc gaccctgtcc atgcgcacgg
    14581 tcgcgctggc ggacgacccc ggcgtgcacc tcaagctgcc gctgcccacg gcgaccctcg
    14641 gcgcccggaa tacccgcagc atcaagcaag gcacgctcgc tgacggcgcc gagatgcaac
    14701 gcctgctggc caaggtgctg gccgccgaac cggccctcgc cgacaccatc gtcctggccg
    14761 acgagtcggt ctgggtggac gacccggacg aataccgcgc ggcgctgacc cggcgctatc
    14821 cgtccgaact ggacggtgcg cacctcgtcc cgctggccgc gttggccgcc cccgatccgt
    14881 ggggcaccgg cacggtcctc gaccgcgtcg ccggcggcga cctcgacgcc tggttcgacc
    14941 gctacctccg ggtgctgctc gacttccacg tcgccctctg gctgcgctac ggcatcgccc
    15001 tggaatcgca ccagcagaac atcacgctcg cgttggccgg agaccgcatt cgcctggtgt
    15061 acaaggacaa cgacggcgcc cgggtggacc cgacccggca gcaggcggcc ttcgccgacc
    15121 ggcgcatggc ggtggcggac ccggccgagc tggccgacgt cttcaccacc atcaccctgc
    15181 acctgtgcgc ggccgcgacc gtccgcgcgg ccgggcgtga cgacctcttc tcgctgatcg
    15241 gccggcgtct cgccgaggcc gccgaccgct ggaccgatcc caccgatccg gcctcggtgc
    15301 gggcggccga gctgttgcgc acccgcgtgc tcgaagcgga tcgcttaccc gtcaaggcaa
    15361 tggtgacggc cggcaccctg ctgcccaagc accgcctcgg ctgcaccgac atcaacaagc
    15421 actacctgcg caccggcccc aactacttgc gccaccggag ttcttcgtga gcatcaccct
    15481 gcccgtactc gcgccgccgc ggtcggcccc gcagcgccag gccgacctcg cctgtgcgca
    15541 cacgctgctc ggctgcgtcg tgcgtgagct ggccgagccc ggcgggcacg ccgtcgccga
    15601 cggcccgcac ctggtcgtca cgctgccgcg gaccggcgtc aggctgcgtg cgcgactggc
    15661 gcggacgtcc acagtgggcg gtcaccggtt caccgatccg gtgcagcaca aggcggacga
    15721 atggggcgac ctcgacgccg cgacgctggc cgagctggtc gccgccgagc tggcagcggt
    15781 cagcggccac ggcaacgacg agttcgtcgg ccaggtgctg gccagccgcg acacgctggc
    15841 cgacctgcac gcccgccggt ccacgagcgc gccgcgcccg gtgggcgagc cggcgtcggg
    15901 ctacctggac tccgagcagt cgctgctcgc cgggcacccg cgccaccccg cgcccaagtg
    15961 gcgctccggg gaccgggcgg cgtggcggcg ctacgccccc gagtaccgga ccgcgttccc
    16021 cttgcactgg ctcgctgtgc gcgcggaggc cgtgcgcgat gtggggcacg gcttcgacgc
    16081 gcacgcccgc accgcatggc tggtcggcgc cgcgttcgcc gggcacgcgc tggttcccgt
    16141 gcacccgtgg cagttccggc tgctcactga cgatccggtc accggactgc cgctggccga
    16201 ggcgctcgcc gacggcacca tccaggacct cggcccggtc ggcgccccgc tgcacccgac
    16261 ggccagcgtg cgcacgctgt accagcccga ggccgacctg ttcctcaaga ccagcctgaa
    16321 cgtccggatc accaactgcg tccggcgcaa cgccgagtac gagctgaccg gcgcggtcgc
    16381 gctcaccgag gcgttggccg agccggtgcg gcgcgtcggg ggccggtggc cgggcttcgc
    16441 ggtgctcgag gaaccggcgg cgcgcagcgt cctgctgccc gagcggtacg gcacgcaggc
    16501 ccaacggttc gcgttgctcg aagggctcgg atgcattgtg cgcgaaggca tcgccgcgca
    16561 cctggagcgc ggcgaccagg tccacctggc cggtgcgctg gcggccgccg cacccgaccc
    16621 ggccggtacc cggacccgca tcgccgacct cgccgacggc gtcgcggacg gcgtgacgtg
    16681 ggcccgcgag tggtggcggc gctacctgga cgtgctggtc gggccggtgc tcgcgttgtg
    16741 ggcgcggcat ggcgtcgtgc tggagccgca cctgcagaac gtgctggtcg tgaccggtcc
    16801 ggacggcatg ccgcgccgcg tgctcgcccg cgacctcgaa ggcaccaagc tggtggccgg
    16861 ccggcaccgc gccaccctcg ccgcgttgcc gccgaaggtc gcgcaggctt gcgcgtacga
    16921 cgaggaccgg gcctggcagc ggatcgcgta ctgcctgttc gtcaaccacc tggccgagct
    16981 cgcgggcgcg ctggccgacc tcgcccagca cagcgcgccg ggcatgtgcc ggttcgagga
    17041 cgagctgtgg gacaccctgg gcgacgtgct cggccggttg tgcgtcgagc tcggcaaccc
    17101 gccgcgtttg ctggccatgt tgcgcggaga accgttgccc gccaaggcga acctgctggt
    17161 tcggtgggct cgggacgccg accggctggc cgggtacgtg ccgctgcgca acccgttcgc
    17221 ccgatgatcg ccgttccgga cgcggtcgcc gaggcggccc tcggcgtcga cggacccacg
    17281 tacctctacg acctgcccgg cctcgacgac cacgtgcgcg cgatccggac cgcgctcggg
    17341 ccgcacgtgg aattcttcca cgccgtcaag gcaaatccgg atctcggtgt gctgcgcacg
    17401 atcgcgtcgc atgtggacgg tctggaggta gccagcgcgg gcgagctggc ccacgtccgc
    17461 aagctcggca ctgacctgct gatcgcgttc ggtggcccgg gcaagaccga cgccgaactg
    17521 aagtccactg tggacctgtt tcacgtggag agccgctacg aactcgcgcg gctgaccggc
    17581 gcgaccgcgt tgctgcgggt gaacctgccg gtacccgaag gccctgcggt gctgcggatg
    17641 ggcgggctgc ccagcccgtt cggcatggac cccgaggacg cacggaaggc ggccgtcgag
    17701 gcgccgccgg gcgtgcgggt gatcggcgtg cacgcccacc tggtcagcgg cgtggacgcc
    17761 gagcaggcgg ccgccgtcgc cggggaagtc gtgcgctggt cggtggatgc cgggcttccg
    17821 cgtgaggtgg tgaacgtcgg cggcggcatg gccgtggact acctgcgccc ggacgaacgg
    17881 ttcgactggg cgcggtacgg acggttgctg cgcgggcttg ccccgcccgg cacggtgctg
    17941 cgcatcgaac cgggccgcgc ggtgagcgcc taccacggtt ggtacgccac ccgcgtgctc
    18001 gacgtgaaac gcagtgcggg ttcgtggttc gcgatctgcg ccggtggcac ccaccacctg
    18061 cgcacacccg ccgccaaggg gcattcccag ccgcttgccg tgctgccgcg gggatcgagc
    18121 ggaccttcgg tcgacgacgc accggtcacc ttcgtcggtc agctctgcac acccaaggac
    18181 gtcctggcca gggacgtcgt cgtgccgcgg gtgcgggtgg gggacgtcgt ggcgttcggg
    18241 atggccggcg cctacgcgta caacatcagt cacaccgagt tcttgatgca cccgaaaccg
    18301 gcggtcgtgc accttatctg acgcctaaat cttcactagc tttcggtttc gtggcaaccg
    18361 aatccccggc tgcgtggtca cactcacaag ctccagggga atggaggggc catgaccgat
    18421 ctgtggggta ttccggggcc acgcttcatc gagatctaca tgggcttgtt ggtcgcaccg
    18481 gcgatcgggg ccgtgctctg gcggtggtgg caggtccggc gggtcaagcc ggccggcccg
    18541 caacggtccg ggatgacggt gcaccacttg gcctacctgg ccggtggacc gaagcgggcg
    18601 gcggaatcgg cggtcgcgtc gctgttggac ggcgagcggc tgcgggtgga cagcacgggc
    18661 gtgctgcaca aggtcggcaa ggcggagccg gcggatccga tcgagcgtgc ggtgttccgc
    18721 cgcgccgagg gcgccaggat caggagcatg ccggtcgtgg tcgcggatgc gacgtacgag
    18781 ctgtcacacg acctggcgaa gcggggcctc gccgtgccgg agaagtccgt cgtcctggcc
    18841 aagcgtgtgg tggcggggct gtacgtggcg atcggcgtgc tggggtcggt ccgggcttgg
    18901 gccggctcgg ggctgggcca cccggtcggt cacctggttt tgctgctggt ggtggacatc
    18961 gcggcgatcg cggtggcgct ctggttcgcc gagcgcggcc ccgaccacct gatcacggcg
    19021 gcgggccggg cgatggtgcg cgacgcgggc cgcacgcgca gggcgggtgc ggccatggtc
    19081 gggccggcgg gcctgatcct cggcggtgcg gccgcctggg tcgcgttgga cgggttgcag
    19141 gcctacccgg acgagacggt ggtctcggcg ttggcctaca caccggcggc cacaggtggt
    19201 ggcttctggg gcggtggcgg cagcggctac tcgtgcagca gcggtgcggg cagttcgtgc
    19261 ggcggcggca gttcgtgcgg cggtgggtcg tcgtgcggtg gcggcggcgg atgcggggga
    19321 tgagcgatga aagaccgtcg tctggctcta cgtggcggtc ggcgtgttcg gcctggtccg
    19381 gctgttcgcg ggcctgtcgg tgcaccaccc ggtcggctac ctgctgttgc tgctcctggt
    19441 cgacgtggcg gccatcgcgg tgtcggcggg gctcgcccgg cgcacgaaga ccgacctggc
    19501 caccgaggcg gggcgggagc tggtgcggga gcagcggcgg aagaaggaac accacggagc
    19561 ggctgccgcg gtgtcgttca acgggctccg ggcctacccg gacggcgacc tcgccaaggc
    19621 gctcacctac agcccgccac caaccaggcg ccccgtgcgt cggactagcg tccgatccgg
    19681 cggcgtcagc tacatggcgg ccggaaccta cgacaccggt tcgtccggca gtgcaagctc
    19741 ttgcggtagc agttcctgcg gcagcgcgag ttcctgcggt ggcgggtcct cgtgtggcgg
    19801 tggcggcggc tgcggcggat gagcagaggg aggggacatg gacacctggg gcattcccgg
    19861 gccgacgttc ctcgcgatct tcggggtgct gatcgcggtc gaggtcgtgg ccgggctggt
    19921 gtggaagagc gcgcaggaga acaggtcggc gaccgggacc gcccggcgcc tcggggtcta
    19981 ccacctcgcg tacctggccg gtgggcggcc gcgggtctgt gagacggcgg tggcctcact
    20041 gctggacgcc gggtacctgc gcaccaacag caagggacag ctgagccagt cgtcccagca
    20101 ggcgccgcgc gagccggtgg agatggcggt cttcgcgggc gcccactcgc ggcgcgcgcg
    20161 tgagctggtg ccggtgctgg agcggccgtg cgacgcgctg gccgacgacc tggcagcggc
    20221 cggttacctg gtgccgcggg ccgcgaccaa gcaacggcgg caggtcatcc tcaccgtcgc
    20281 cgtgctggtc gccgtgctcg gcctggcccg gctggtctcg gggatcgcgg cggagaaacc
    20341 gatcgggtac ctgatcccgt tgttcatcct cgcggacgcg gtcgcgatct tctgcttctc
    20401 gttctcgcgt tcggcgcgcg ccgacgtgac gaccaaggcg ggcaaggacc tggtcaaccg
    20461 gtcccgccgc ggcgaccggt cggtcctgcc gctcgcggtg ggcagcggcg tggccgtcgc
    20521 ggtcgcggtg gccgggctga gcgcgttccc ggacgagcag atcgtgtcgg cgctgggcag
    20581 cgtgccgcag cagacggcgt tcagcgggta cagcggcgac ggcgggtcgt cgtcgtcctc
    20641 gtgcggtagc agcagttcct gcagcggcag ctcctgcggt gggggcagct cctgtggtgg
    20701 cggtggcggt tgcggcggct gagttgaagg ggaggtagcc atgcagacgt ggggcatttc
    20761 cgggccggat tggctgaagc tgtacggggt cctgctcgtg gcgccgttcg tggtcgggct
    20821 gctctggcgg ctcgtccagg tcatgggact cgggcggccc tccgccacga cgtccaccag
    20881 cctgaccgtg caccacctgg cgtacctggc cggtggccgg cgccggatgg cggagagcgc
    20941 ggtcgcacgg ctgctggccg cgcagcgggt ccgggtcagc aagaagggcc tgatcagcgt
    21001 gatcccgggc cagtcgctca cggacaaggt cgagcgcacg gtgctcgggc tggccagccg
    21061 caagcggctg ccccaggtgg tcggcaagct cggcccgctg gccaccaagg tgaacggcga
    21121 gctggccgag cagggtctgg ccgtgccgga gaaggccgtt cagctgcgcc gcaaggccgt
    21181 ggccctgctg tcgctcgcct tcgtgctcct cggcgtcgtc cggatggggg cgggggtcgc
    21241 gaacgaccgg ccggtgggct ggctggtcct cgaagtgctg gccggggtcg cgctgatgat
    21301 cgtggccttc cggttgcgac ggcgcgacac cacgctggcg acgatgtcgg gtcggcggtt
    21361 gttgcgcgag gccaaagccg cgcaccgcgg gcggacctcg acgggcagcg cgggcctggt
    21421 gctggccgga gcgggcgcgg ccggtgcggt cgccctcggc ggcatggcgc tctacccgga
    21481 cccggccatc cagaccgcgc tcgcctacgt cccggcgtcg ttctccggcg gtgggggctc
    21541 gggtggcgga ggctccaact gcagcagcgg cagcagctgt ggtggcggta gcagttgtgg
    21601 tggtggcggc ggctgcggtg gcggaggtgg ttgcggtggc tgacctggct gacctcgcgg
    21661 acctcgcgga cctcgcggac ctcggggtcg gcatcggctg gcggcccgag atcgacctga
    21721 ccgtggcgcg gttgcccggc gtggactggg tcgaggtcgt cgcggagaac ctgcacgtcg
    21781 agcacctgcc cgagtcgctg gtcgagctgc gcgccaaggg cctgccggtg ctgccgcacg
    21841 cggtctcgct ctccctcggc ggtgccgacc cggtggatcc ggcgagggtc gagcacctgg
    21901 cggccgtggc cgcggcgctg gacgcgccgg tggtcagcga ccacgtctgc ttcgtgcggg
    21961 ccggcggcct cgactccggg cacctgatgc cgatcccgcg cacccgcgat gcactggacg
    22021 tgctggtggc caacgtgacc accgcccagt ccatcctgga aaccccgctc gcgctggaga
    22081 acatcgccgc gctgatcgag tggccggacg cggagctgac cgagggccag ttcctggccg
    22141 agctcaccga acgcaccggc tgcgcgctga tcgtcgacgt cgccaacctc tacgcgtgcg
    22201 cccgcaacat cggtctcgac atcgagaggt tcctcgacga gatcccgttg gagcgcatcg
    22261 cgtacgtgca cgtcgcgggc ggcgtcgaac acgacggcgc ctaccacgac acgcacgcgc
    22321 acccggtcct cccgcaggtc ctcgacgtgc tcgcgcggct gcgggaccgc acccagccgc
    22381 cgggcgtgct gctcgaacgc gacgacgact acccgtccga cagcgaactg gccgacgagc
    22441 tggcccgcat ccgcgcggtg gtgggccgat gaccagagaa gagctggccg ctcggcaggc
    22501 gcagttgcta tgggccttgc tggccgacgg cgacccgccg ccggggttcg ccgccgagga
    22561 cctcgagcgc gaggcgaaag ccttgtgggc caagcggcgg cgggtcaccg cgatgctgcg
    22621 cccggacgtc gccgaggagc tgggcgagca gtacgtggcg gcgttcgacc ggttcgcgcg
    22681 cagccatccg aagagcgtga ccacccgggc ccgccaggac gccgacgact tcgcggcctg
    22741 ggcgatcgcc gagggcctgc tcgcgtcgcc accccggcgt ccttggtgga aactcaagga
    22801 ccggtccagc gggggtcggt aagctcggtg cggtgaccga cgcaagcctg ctcgccgtga
    22861 gcgacctgca tgtctcgtat gccgagaacc gggagatcgt caccggcctg tggccggacc
    22921 acgagggcga ctggctgctg gtcgccggcg acatcggtga gaaggtcgcc gacatcgaat
    22981 ggaccctcgg cacgctcgcc gaccggttcg ccaaggtgat ctggtcgccg ggcaaccacg
    23041 agctgtggtc gggtgggtcc gaccccgtgc agctcaaggg cgtcgcgcgc taccagcacc
    23101 tggtcgagat gtgccgcggg ctcggcgtgg tcacccccga ggacccgtac gaggtctgga
    23161 ccggcgcggg cggcccggtc accatcgcgc cgctgttcac cctctacgac tactcgtggc
    23221 gcccggccgg aacccgcacc aaggccgaag gcctggccgc ggcgcacgag gccggcatcg
    23281 tctgcaccga cgagtacttc ctggacccgt cgccctaccc gaccagggac gactggtgcc
    23341 gggcgcgggt ggccgagacc gagcgcaggc tggccgccgt cgaaggcccg accgtcctgg
    23401 tgaaccactg gccgttgcgc cgcgagccga cgctcgtgtt gcggtacccg gtcttcgcgc
    23461 agtggtgcgg caccgacctg accgccgact ggcacacccg gttcaacgcc gccgcgatgg
    23521 tatacgggca cctgcacatc ccacggtcca ctgtgtacga cggggtgccg ttcgaggagg
    23581 tctcggtcgg ctacccgagg gagtggcagg cccgacggaa acgggagcgc tgggtgcgca
    23641 cgatcctccc ggccgcacaa caggtggagc gcgcatgatc gaccggatcc tgccggccaa
    23701 ggccgtcgcg gtcgaggcgt tcgaagaccc gccggaggcc gtgctgctgc cggtcgaggc
    23761 ggccgcggtg gcgaaggcgg tggcgaaccg ccgccgcgag ttcaccacgg tccgccactg
    23821 cgcccggctg gccatggcca aactcggagt tccctacgtg ccactggttc cgggcgaacg
    23881 cggggcgccc agctggccgt ccactgtggt cggcagcatg acgcactgcg ccgggtaccg
    23941 ggccgcggtg gtggcgcacg cgaccgagtt gcgctcggtc ggcgtggacg cggagccgca
    24001 cggcccgctg cccgacggtg tgctggacgc ggtgtcgctg ccggccgagc gggatcacct
    24061 ggccggcctg cccagcagcg tgcactggga ccgcttgttg ttcagcgcca aggaaagcgt
    24121 gtacaaggcg tggttcccga tcacccagcg ttggctgggt ttcgaggaag cctcgctgga
    24181 attcgccacc gacgggacgt tctccgcccg cctgctggtg cccggcccgg tgctcgacgg
    24241 cgtcgagctg cggggcttcg agggccgctg gctggtcgag gacggcttcg tgctgacggc
    24301 catcgccgtc cccttcgcct gacgggcgtg tcccacactc gcgccgggtg tgtcccccgt
    24361 tcccgccggg tgtgtcccac actcgcgcgg ggtgtgtccc acactcgagt gtgggacacg
    24421 ctcgtcctga gtgtgggaca caccttgcct gagtgtggga cacgcccgga ggcggtcagg
    24481 ccagagcggc ttcgcggcgg tagctgaaga cgaccagcgc gctcaacgcc accgtccagg
    24541 cccccagcac cagcaccgcc agcgcggtgt tgttgttgcc cagcaacgcg ccgtgcccga
    24601 tgtcggccag ccagtagctg ggaatcgcct tcaccgcgga cgcgacccag ctcgggaacc
    24661 cggtcagcgg gatcagcaga ccgctcagga aaccgaagcc cagctggacc ccggccgtgt
    24721 agatctgcac ggagtccgcc gaggcgagca ggccgagcag cacgccgagc accgcgaacg
    24781 gcaacgacgc gagccacgtg cccaacgtca gctgcaccca cgcacccgcg ctcaggtgca
    24841 cgttctcgat gaagccaccg gccatggcca cgataatcgg cgcgggcagc gccacgatca
    24901 tgctgaccac caccttcgac agcaggtacg ccttcgggct caacggcgtg agccgcagtt
    24961 gcgcctgcca gccacccgag cgctccgccg cgatccggat gccggtcgac agcgccgaca
    25021 cgaacgcccc gtacgcggcg agcccgcaca acaggtacgc cttgtacttc acgtcggtgc
    25081 cgggcaccga ctcgtccttg tacagccccg attgcaacag gtagagcagg gtcggcaacg
    25141 cgatcgcgaa cagcacgaag cgcggggtgc gcaacatgcg cttgatctcc aacgtcaggt
    25201 agccggtcat cgggactcct cggtgctgat gctcgaaccc gcaagcggtt cttcggtgct
    25261 gatgctcgaa cccgcaagcg gttcttcggt gctggtgagc gacaggaacg cctcttcgag
    25321 gcccatcgcg gtgatctgga agtggtgggc cagcgggtgc tcgacgagca gcgcgcgcaa
    25381 cgcggtgtcg gagtcgtcgc agctgagctc ggcgcgatcg ccacgcaact cgccaccggt
    25441 cacgccgggc aggcgcagca ggtcggcgag cgtcgcgccg ggcacgaccg cgcgcagcac
    25501 gctgccggtg acgctgccac gcacctcggc gaccgtgccg tcggcgacca cccggccgtc
    25561 gcgcagcagc acgacccggt cggcgaactc ctcggcctcg tcgaggtagt gggtcgcgaa
    25621 cagcacggtg cggccggtgt cggtgaacga gcgcatggcc tgccagaagt cgcggcggct
    25681 gccgacgtcc atggccgcgg tgggctcgtc gagcaccagc aggcgcgggt cgccgaccag
    25741 ggccatggcg aaccgcacgc gctggcgctg gccgccggag agcttggtgc agtagcggtc
    25801 ggcgatgtcg gtgacccccg ccatccgcat cgcctgctcg gcgggcatcg ggtgcttgtg
    25861 gagcccggcg atcatgccga tcacctcggc gaccgtcacg tcctcgagca ggttgccctg
    25921 ctgcagcatc gcgccgacga ggccctcggt gaccgcgtcg cgcggcgtct tgccgaacac
    25981 ctcgacggtg cccgcgctcg gctgggtcag ccccaggatg gtggccacgg tcgtcgactt
    26041 gccggccccg ttcggcccga gcacggcgac cacctcgccg gtgccgatgg ccaggtcgac
    26101 gcccctgacc gcggcgaccg tgccggtctt cgtttcgtag ttcttgcgca ggtcgcggat
    26161 cgtcacggct tgcgtggtcc gcggtggtgt ggtctggact ggcatggctc gaagtctgtg
    26221 tccgcaaagg accacgaccc cggtacggcc gtcacgggtt cgggatgaca gatgtcatgg
    26281 gccgggtccg gcggcgtcgc ctagggtctt gttgtgcagg gtcaactctc cgaggacgcc
    26341 gaacgggccg cgcggctgcg ggcctacgag ttcaccgcga accagtggcc ggcttggggg
    26401 ttcgccggcc gtgatcgcga ccgcaagcag aacgccgtgg tgcgcaacct cttcgcgccg
    26461 gtggcgttca tgttcttcat gttcgccgcg gtgcgcgacg acctggccgg gccgcacccg
    26521 atcgtccaac gggtgctgct cgcgatcgtg gccaccgttt acgcgttgag cttcgtcgcg
    26581 gtgctggtgg cccggatgcg ggtgcaggct tcgcaccgca cgcgggcgct gatcgtggcg
    26641 tggatgctgc tgctcggcgg gttgctgccg gtggtctcca tggacgccaa ggacttcccg
    26701 atgatcacct acgccatggt gatcacggtg ctcgtcgtgc cgctgcgcta cagccgcccc
    26761 atcggcgcgg tcgtgatcgg gctgcagatg ctgatcacct ggctcgccga cggtgcggtc
    26821 gactggagcg gcacgtggac gctggtgctg gtcaccgtgt cggtcacgtc gttgctgatc
    26881 gtcggcaaca ccatccagag cctgcgcgac gcgaacagca tgatcgcgga cctcgccgtc
    26941 gccgaggagc gcagccgctt cgcccgcgac ctgcacgacc tgctcggtca cagcctgacc
    27001 acgatcacgg tgaagtcggg cctggcgcgg cgcgtgctgg agaccggcgc ggcgaccgag
    27061 cgggcgatca gcgaggtgcg ggacgtggag gagttgtcgc gcaaggcgtt ggtcgaagtg
    27121 cgggccgccg tgtcggggta ccaccagatc tcgctggccg cggagttggt gaacgcgaag
    27181 gccgcgttgc gtgccgcggg catcgaggcg gtgttgccgg gcggggtgga ggagttgcgc
    27241 tcgtcgctgc gcgagcagtt cgcctgggtg gtgcgcgagg gcgtgacgaa tgtggtcaag
    27301 cacagcggcg cgtcccgctg cgaggtccgg ctcggcgagt cgtggctcga ggtgcgggac
    27361 aacggccggg ccggctcggg gagcccgtcg gcgggcaacg ggttgcgtgg cctgcgcgac
    27421 cggctcgcgg cgtccggctc gtccctgacg tgggagcggg tcgacggctg gttcgtgctg
    27481 cgcgcggccg cttaagcgag actgtaccgt ctcgtatgat aaggtccggt tcatggcgac
    27541 ttcgaccgaa ccggcccggc gcggccgtcc gccgtcatcg cagaagcggg cggccatcct
    27601 cgaagcggcg acgtcggtct tcctggacaa cggctacgac cgcaccaacc tcgacgatgt
    27661 agcggcggtc gcgggtgtgt cgaagcagac cgtgtaccgg cacttcacgg acaagaagtc
    27721 gctgttcatg gccgtggtcg aggccgcgcg ggagcagcag ctgcggcccg ccgacgcggt
    27781 cgccaccgtg ctggaccccg acgacctgct cggctcgctg acccggttcg gcgagcggat
    27841 gctgacggtg gtgttgagca agcgggtggc ggccctgcgc cgggtgatga tcggcgagct
    27901 gagccggatt cccgaactgc gcgagatgtg ggcggccggg gcgccgacgg cgatcgcgac
    27961 cgtgctgatc accgagctcg ttgcgctcac cgaacgcggc gtgctggacg tgccggaccc
    28021 ggtggccgcc gtggagaact acttcggcct gctttccttc cgcggcatga acaacacggc
    28081 ttacggggtg accgagctgt cggccaagga ccgcaaacgc atcgccgaat cggccgccga
    28141 cctcttcgtt cgcgcctact cccgctgatc ctcttgttgc tggggttttc cacaggcggg
    28201 tgtggctgtt gtgggtggtg gcttgtgttc tggggtggtt gctctcgagt gggtgttcgc
    28261 cgcccggtgg tggggttggt ctcggggtgg ggcggtgggc ctcgattagg agcggctgcc
    28321 gcgggtgttc gccgctcggt ggctgggttg gtctcggggt tggtggcggc gaacaccctt
    28381 gccaccggtg ccggtgattg cgtggcgggg gtggcccggt tgaggggtta cgttgcgagg
    28441 gcagccggcg gttccccggg tcgtcccggc ggtggctgag ttacaggaat ttacgcagcg
    28501 ccttgtagcc agggtggtgg ggtgaatact ggcagcccgt tatccatgtg caccgcccat
    28561 tcggtgtgat ggatcaaccg atgatgataa gggcacacca ataccagatt atcgagcgtt
    28621 gttggtccgc cgtcggccca atgtttgatg tgatgcgcgt gacattgatg cggtgttcgc
    28681 gcgcagccgg gtgcggcgca gccttggtcg cggatggcga gggctctgcg caatcgttta
    28741 tcggccaatc ggcgggttcc ccgatatcca gtggctggga tttgccgtcg aggacgatgg
    28801 ggatgagttt cgcctcgcag gccacgcggc gggcctgctc cggagccagc gtgcggccat
    28861 catcgagcat cgcgcggccg atccgagtct gcagagtctc cagagagacc gtcaccgcga
    28921 tgtgcggacg ctcgccaccc tcagccggag cccggccgga gtcggcggcg aagccgatga
    28981 tctcggccag cgcgtcgccc tgccgctcgc tcaggatccg gtcatcctga ggctggggct
    29041 tggccagtgg ggagagcagc gcgcgcagca cgctcgcgtc ctcggcgccg agccggaact
    29101 ggcctgacag cgacccgtcg cggtgttcgt agaggtccag cgtgttctgc gcgtccacca
    29161 cagtcggctc gaccggcttg cgaccgtcgg ggttcagcgc gtcgacgatg cgcttaccga
    29221 ggtggatgag ctgggtcggg ttgaactccc gagccagctc ggtcatgtct acgtcgacct
    29281 gttcggcgtg ctcgaccggg acgagttcca ccgcggtggc gatcttgtcg acgtgcgcgc
    29341 cagagatctc cccggccgtc atcgccgccc gcgcggcagg cagccgcggc gggatcgact
    29401 ggccggtgat cccgaccttc gggcacaaca actcgacgtg atgttcaaga cgcttggctt
    29461 caggagcggt cagatgcagg acatcctgca gaaaccgcca caactgggga tacccggact
    29521 ctttccactc caggtgggaa atgtcgtcga gcagcttcaa ctccagacgc cgcaactgcg
    29581 cgacagtcga gttaagctcc cccagctcca tacctcgatc ataccacaac aatcgaccaa
    29641 acggcctaac cgggaatggt ggaatattcc gattcttcac gcagcccggc accaacggga
    29701 ccatccaata aaccgcaggg ggcgaacacc ctcggcagcc gcccctaata gctcctaata
    29761 gagggcaact agcaaaggca agctcaggct tgagccaacc catgccgtag cgcataccgc
    29821 acggcgtctg ctcggttctt ggcgccgatc ttggcgaatg cgttgttgat gtgcgtcttc
    29881 accgtcgtct cgctgatgaa cagcgacgcg gcgatctccg tgttgctcga accgccaccg
    29941 atcaggccga gcacttccgc ctcccgggcg gtcaggtggt ccggtggcgg ttccgggcgc
    30001 gttccggtca gtgcgctggc caaccgggcc gacaccaccg ggtcgaaagt ggactgtccg
    30061 accgcgcagg accgcactgc cgcgaggatt tccgcccggc cggcatcctt ggtgaggtat
    30121 ccgcgggcgc cggcacgcaa ggcggaaccg atcgactcgt cgtcggcgta ggtcgacagg
    30181 accagcacgc cgatgctcgg gtgccgcttc acgatttccg ccgtggccgc cacgccgtcc
    30241 atgcgcggca tgcgcaggtc catcaacacc acctgcggca ccgtctccgc cgccagccgg
    30301 acggcctccg cgccgtcgcc ggcgtggccg accacggtca cgccgtcgag cagcccgagc
    30361 agcgccacca atccttcgcg gaccagttgc tggtcgtcga ccaccagcac ccggatgtcg
    30421 gtcacgtctc caccccgatc tccaccgccg ggtggtccac ctccacccgc ccccgcacct
    30481 agcgtcgtcg ccatggaagc acatgacgtg atgaccttgc tgctcgtccg cttcgcgatc
    30541 gtcgcgggcg ggatcgcgtt gctcgcggtg gcggcgttca ccgtgctggt cgtgctgaag
    30601 cgcaatggca agcaggtcga cgcccgccgc tacgtcgagc cggtggtgcg ctcgtgggcg
    30661 cagagcccgt ctcggcgccg gcggcggggt ggcgccgcca agtttgccac ccgcacggtg
    30721 ctcaaccacc tcgatcgcga ggaccgccgg tgatcgagga actcatcacc gactacctga
    30781 tcaaggtggg catcgtggtc ggcttgggcc tgctcgcgct ggtcgcgatg gttatcatct
    30841 accgcaaagt cggcagcaag tagggaactt cgtgaccgac cacctcatcg accgcctcgc
    30901 gccgggctgg ctggtggtgc agctgctcgg caccgcgatc ctggtcacgg tggtgatcac
    30961 cgccgcgcct gccaacgctc tcttgtggac ggtctacggc atcggcatcg gttgctggct
    31021 cgcgttcatc ggcctcgacc aggtgggctc gcgttgggcg gtgccggtgc tcgtggtgag
    31081 catcgtcgtg cccgcgctgg cggtcgggcc cgcgccggac gccaccgcgc tggtcatctg
    31141 ctgcgtgctg ctcggccgcc tcgcttccct gcccgagccg agcgggcggc tgatcctgtg
    31201 gctcttcgtc tactgcgagg cgtgcac
//
