LOCUS       NZ_SNXZ01000004        26852 bp    DNA     linear   CON 20-APR-2024
DEFINITION  Labedaea rhizosphaerae strain DSM 45361 Ga0310470_104, whole genome
            shotgun sequence.
ACCESSION   NZ_SNXZ01000004
VERSION     NZ_SNXZ01000004.1
KEYWORDS    WGS; RefSeq.
SOURCE      Labedaea rhizosphaerae
  ORGANISM  Labedaea rhizosphaerae
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Labedaea.
REFERENCE   1  (bases 1 to 770598)
  AUTHORS   Goeker,M.
  TITLE     Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing
            the most valuable type-strain genomes for metagenomic binning,
            comparative biology and taxonomic classification
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 770598)
  AUTHORS   Goeker,M., Huntemann,M., Clum,A., Pillay,M., Palaniappan,K.,
            Varghese,N., Mikhailova,N., Stamatis,D., Reddy,T., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-MAR-2019) Prokaryotic Super Group, DOE Joint Genome
            Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.12.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 180.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004362825.1-RS_2024_04_19
            Annotation Date                   :: 04/19/2024 13:11:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,820
            CDSs (total)                      :: 7,753
            Genes (coding)                    :: 7,690
            CDSs (with protein)               :: 7,690
            Genes (RNA)                       :: 67
            rRNAs                             :: 3, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2 (5S)
            tRNAs                             :: 59
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 11 of 63
            Pseudo Genes (incomplete)         :: 55 of 63
            Pseudo Genes (internal stop)      :: 3 of 63
            Pseudo Genes (multiple problems)  :: 6 of 63
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 17:41:24
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 15076
            Orig. end                         :: 41928
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            SNXZ01000004.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26852
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..26852
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26852
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:16852](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16852
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(130..144)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     misc_feature    complement(1654..1668)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.35"
                     /tool="antismash"
     misc_feature    1715..1728
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.18"
                     /tool="antismash"
     gene            complement(1768..2460)
                     /locus_tag="EV186_RS22740"
                     /old_locus_tag="EV186_10410"
     CDS             complement(1768..2460)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013224207.1"
                     /locus_tag="EV186_RS22740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_10410"
                     /product="VOC family protein"
                     /protein_id="WP_133851438.1"
                     /transl_table=11
                     /translation="MLVNVVVDAASPAHLAEFWSEMLSGWFVREEPEGEVDVVAPSADG
                     ATLDLVFVPVASPKRGKNRVHLDLASNGPEHQAELVDRALTAGATHVDIGQGDVPWVVL
                     ADPEGNEFCVLEHRAVYAGSGRLASIVMDTPDPAALAPFWATATGWEVVRAEPRFASLR
                     APDGRGPWLELLRTNDPKVGKNRVHLDVRGVEVERLVGLGAGRVDVGQGDVPWAVLEDP
                     QGNEFCIL"
     misc_feature    complement(1936..1938)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(2491..3288)
                     /locus_tag="EV186_RS22745"
                     /old_locus_tag="EV186_10411"
     CDS             complement(2491..3288)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020671610.1"
                     /locus_tag="EV186_RS22745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_10411"
                     /product="maleylpyruvate isomerase N-terminal
                     domain-containing protein"
                     /protein_id="WP_133851439.1"
                     /transl_table=11
                     /translation="MTPRLDHEQLLQVLAIEAGVLAGVASDAPSRARVPHCPGLTLGET
                     VRHLGALYRASLSWITTGRKPVEWQREPGPDQSLLEFYRIGLRDVMTELAAHDPADPCA
                     SWSKDKTYGFWIRRLAHETTVHRIDVQGAAGLPIAAVDDDVALDGADEVLTEWFVSKLR
                     VLGIRNTQDAVLTVRCEGVDGGWMVRAPRGVDTAAWWMPDLDHARESVNGTVVGRNPQA
                     LYLWLWGRKSPWGDPQPDGRRDLTFTGMDAVGQLWALLRLATR"
     gene            complement(3285..3728)
                     /locus_tag="EV186_RS22750"
                     /old_locus_tag="EV186_10412"
     CDS             complement(3285..3728)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018686257.1"
                     /locus_tag="EV186_RS22750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_10412"
                     /product="SAV_6107 family HEPN domain-containing protein"
                     /protein_id="WP_166659288.1"
                     /transl_table=11
                     /translation="MSTTLDFPAPTLGAGRRYVPFPGDSESAGALLAQAERGLADAELE
                     RDAGQRFAAAYLSALRAAAAMLALRGRPHRGRARPTSVWTLLSSVAPEFGEWAAFFAAG
                     SATRARVQAGITRHVTARAADDLVRQAGQFIELVGRAVHGSST"
     misc_feature    3846..3861
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: medium, score: 25.27"
                     /tool="antismash"
     misc_feature    complement(3847..3860)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 21.07"
                     /tool="antismash"
     gene            complement(3920..4453)
                     /locus_tag="EV186_RS22755"
                     /old_locus_tag="EV186_10413"
     CDS             complement(3920..4453)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012655.4"
                     /locus_tag="EV186_RS22755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_10413"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_243754217.1"
                     /transl_table=11
                     /translation="MRRTRRGLQEALFALIFEKGYDRVTVQDVLDRADVGRSTFYTHFR
                     DKEALLLAAFDALSEDLRGELGAVASDPARPAEALFRFAYERQPAFRALCGKQGGEVVQ
                     RHLRRMLTELLMAQLCLGKPVVPAEVVVEFCTSTTLGLLGWAVDNGFPHDAAWLAAAYR
                     RLVEPGVRAVLRPA"
     misc_feature    4575..4589
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.08"
                     /tool="antismash"
     gene            4607..5326
                     /locus_tag="EV186_RS22760"
                     /old_locus_tag="EV186_10414"
     CDS             4607..5326
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EV186_RS22760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EV186_10414"
                     /product="hypothetical protein"
                     /protein_id="WP_133851441.1"
                     /transl_table=11
                     /translation="MPFSIWLLVLVGALGIPAVTCAALYRGALVVGRSGPDARRIAVLA
                     GVAWAAWTALIWALAAAGLFHLPPTQPQPWIPVAVVLGVVIVVAASRRPAARAILADPG
                     ALRLLAWPQVLRVVGVVFLIAMAMGRIPAAFALPAGIGDIVTGLAAPFAIRSGRVLWLN
                     IVGLLDLVVALALGLLTGVGQGQILAVSPSSELVSTLPLVLIPLAAVPLAIGLHLVSMT
                     RMGALARESRRRHVVAA"
     gene            5339..5863
                     /locus_tag="EV186_RS22765"
                     /old_locus_tag="EV186_10415"
     CDS             5339..5863
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018686258.1"
                     /locus_tag="EV186_RS22765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_10415"
                     /product="YbaK/EbsC family protein"
                     /protein_id="WP_133851442.1"
                     /transl_table=11
                     /translation="MSSFDHPSVSKVAAILREAGVTDGADRIRILDDEARTAALAAQAL
                     GIEVGAIANSLVFVAHFADGHTEPLLALTSGAHRADTGRLAALAGADKVTKARAEFVRE
                     HTGQPIGGVAPVGHPEPVRTVVDNHLATYPEVWAAAGHPKSVFPTTFAELVALTGGTAA
                     DVAAEEDHLPS"
     gene            5860..6429
                     /locus_tag="EV186_RS22770"
                     /old_locus_tag="EV186_10416"
     CDS             5860..6429
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099095.1"
                     /locus_tag="EV186_RS22770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_10416"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_133851443.1"
                     /transl_table=11
                     /translation="MTAAESSSPDRLAELSAQDLRARLSEALDLYVTAMRYPKGTAEQR
                     APMWLAHMMRTGWRCIGAFDPNGNLAGIAYGYRGSPGQWWHEQVRRGLIERSGPAAADQ
                     WTLDYFELTELHVRPDRQGRGTGENLLRALLAGATEGRVLLSTPEGPSRAWRLYRRVGF
                     VDVLRDYQFSGDPRLFGVLGATLPLA"
     gene            complement(6464..8155)
                     /locus_tag="EV186_RS22775"
                     /old_locus_tag="EV186_10417"
     CDS             complement(6464..8155)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005156533.1"
                     /locus_tag="EV186_RS22775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_10417"
                     /product="DUF885 domain-containing protein"
                     /protein_id="WP_133851444.1"
                     /transl_table=11
                     /translation="MPEDQHSDRTIHALSDEFVGHYAALDPLTATAVGLPGHDAEMTDF
                     SPEALEQRAELGRAALARITAATPADDGERVAQAVFAERIGLELEIYDSGWAHADMNVI
                     GSPVHHVRQIFDLMPTETADDWAVIAGRMSAVSDAVDGVIESMRYAAARGKVVALRQVT
                     KVAEQCDVWSGASDEKAFFAALADQANTEDEALRKKLTAAAGDASAAFARFASFLRDEL
                     AAKAPEKDAVGEERYRMWSRQFLGSRLDLQEAYEWGWAEFSRIETEMKQVADRIKSGAT
                     LKEAAAALDADPRYRVTGKAGLEQWMQQLSDAALADLRGTHFDLPDELMKLECLVAPPG
                     GGVGAYYTGPNDDFSRPGRMWWSVEPGREDFSTWREVSTVYHEGVPGHHLQIATAVYER
                     ERLNDFQRMLCWVSGHGEGWALYAERLMRELGYLEDDANLFGMLDAHLFRAGRVIVDLG
                     MHLELEIPRGTGFHEGERWTPELGLEFMLNRTITDPAQVTDEIDRYLGWPGQAPAYKLG
                     ERLWLQAREEARARHGAAFDLKTFHQQALALGSMGLDTLREQLARL"
     gene            8224..8886
                     /locus_tag="EV186_RS22780"
                     /old_locus_tag="EV186_10418"
     CDS             8224..8886
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099092.1"
                     /locus_tag="EV186_RS22780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_10418"
                     /product="DUF3153 domain-containing protein"
                     /protein_id="WP_243754218.1"
                     /transl_table=11
                     /translation="MRTRPRRWLSVLVLGVLTMLCLSGCVRVRAAMAVSPNDLVSGEIV
                     IAAQPTRAGDQGPELEIPDAVKARTSTKAYNVDGYVGNTLSFHDLTFEEVRELSSSINP
                     NSQHFQMSFRRSGDLVTMSGSVDLTGLPTDKADVQIKLAFPGRVTKTDGIDEDGAITWK
                     PKAGEVTEFTATAEYSTKGQSSWTRWVMIVAASAIGVALLVAILAYAARRVSLRQVQ"
     gene            complement(8887..9771)
                     /locus_tag="EV186_RS22785"
                     /old_locus_tag="EV186_10419"
     CDS             complement(8887..9771)
                     /EC_number="1.5.1.20"
                     /GO_function="GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA]"
                     /GO_process="GO:0006555 - methionine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332694.1"
                     /locus_tag="EV186_RS22785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_10419"
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="WP_133851445.1"
                     /transl_table=11
                     /translation="MTSVLERISVGRPVFSVEFFPPRDEADQQILGRAIRELESLDPAF
                     VSVTYGAGGKSRRGTIEATRLIAEETTMTPMAHLTAVDHSVAELRNMIGWYAAVGVRNI
                     LAVRGDPPGDPYGDWIAHPQGLNYAEDLVRLVRSLGDFCVGVAAFPYGHPRSADLDTDT
                     RHLIAKFRAGAHFAIAQLFFEPDDFLRLRDRVATVDPDALLLPSVMPLTTVRTLHKTAE
                     LAGVDVPAWIAERMDPLAGDPAGFRAAGIDLVTNLCERLLAEGVPGLHFITMNRSKATR
                     EVVARLGLLPTRA"
     gene            10001..11053
                     /locus_tag="EV186_RS22790"
                     /old_locus_tag="EV186_10420"
     CDS             10001..11053
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018686263.1"
                     /locus_tag="EV186_RS22790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_10420"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_243754287.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.4e-48, bitscore:
                     160.2, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLATYLAAKRAQLTAAEPSAGDAVDALADFVLGGGKRIRPTFAWW
                     GWRGAGGAADGAEAEKVLTAISALELIQGCALVHDDLMDDSALRRGKPTVHVDFAGRHR
                     AAGWHGDPDKFGAAAAILIGDLALAWADDLFTEAGLTAAQLLAAGPAWRGMRAEMLAGQ
                     YLDVLTQSDGGAPLPPAEAAMRVARLKTAAYTVERPLHLGAALAGAGERTVGALRAFGG
                     DIGVAFQLRDDLLGMFGDTAVTGKPAGDDLREGKRTLLIAVAVTNAEQAGRDATVEMIH
                     EALGNPKLSADDLDRVREALVDLGAVAEVEARIERLTGTALEALASAELAAPAGDRLAA
                     LADAATRRSY"
     gene            11053..12513
                     /gene="crtI"
                     /locus_tag="EV186_RS22795"
                     /old_locus_tag="EV186_10421"
     CDS             11053..12513
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018686264.1"
                     /locus_tag="EV186_RS22795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_10421"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_133851447.1"
                     /sec_met_domain="DAO (E-value: 3.5e-16, bitscore: 55.3,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTVPGRTDHVVVIGAGLAGLSATLHLLGAGRSVTLLEAADGPGG
                     RAASSFVGGQRVDTGATVLTMPEYLDDALNAVGAKLAGRVDLVPLHPAYRAHFADGETL
                     ALHTDADAMAAEIRRFAGPRDADGYLRLRQWLTKLYVAQRDRFIATNFDSPLDLLGPQL
                     ARLVALGGFGRLSPAIARFLPDERLRRLFSFQSLYAGVPPQRALAAYAVIAYMDTVAGV
                     YYPKGGMGTVASALADAAVEAGADVRYATTAAWLERVGGRVRAVRTSTGQRIPCDAVVV
                     TADLPAAYRLLGLTPRRPVGLRWSPSAVVMHLTVDHEWPALDHHTIFFGQAWDRTFSEI
                     TSGSLMTDPSLLVTNPAATDPRPGGGRPLSVLAPCPNLATGRIDWPRVGPAYRDELLRT
                     LAGRGLSGIGDAEVHEVVTPADWAARGMGAGTPFSLAHTFAQTGPFRPRNLVRGAENVV
                     LAGCGTTPGVGIPPVVLSGKLAAARIAD"
     gene            complement(12605..14062)
                     /locus_tag="EV186_RS22800"
                     /old_locus_tag="EV186_10422"
     CDS             complement(12605..14062)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EV186_RS22800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EV186_10422"
                     /product="hypothetical protein"
                     /protein_id="WP_133851448.1"
                     /transl_table=11
                     /translation="MARARARRWPLGVGLTVTSRTRPRVRRGAGVVLPLVLLAACDSSV
                     AGQAGVGAPPPPTTAQVAGQSLTDLAEAGALHVTGGLTTLSGDKVTVDLRVASTGEALG
                     TLTVNGQRAKVVLLSKTPYLNGPAAFWAALPGIPDAKSTVVADRWVSVPPALLGVQIED
                     LFSPPALAQLLADGPAPTAQQPPEANRRQKVGGVDALAIDLSAGTEFVTPTAPHRVVGA
                     KLASVGQAGPSAARDLDLAFTDATAALPSLYRDVDGQAATLAAPVDLITPVEEGSHRFA
                     ECGQASCAVIVDLTNGAKVAVRVSVSADWIGDGKPLGRCDTQTGLVAPGEQISATCTIT
                     SPQWTAFYQNAHSVPGQHPYRAEWSAVSLADPPDRKAVHAHATAKAPAKPAKNGAYVVY
                     AIDHAKGGHARDMWKYGVVASGYWRDQAAQQLDACQSATGRMCAFHQVTTANDAPTAYA
                     AQQQLIADYRASAKRCPAGQAVACDQK"
     gene            14535..15959
                     /gene="mptB"
                     /locus_tag="EV186_RS22805"
                     /old_locus_tag="EV186_10424"
     CDS             14535..15959
                     /codon_start=1
                     /gene="mptB"
                     /inference="COORDINATES: protein motif:HMM:NF038066.1"
                     /locus_tag="EV186_RS22805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_10424"
                     /product="polyprenol phosphomannose-dependent alpha 1,6
                     mannosyltransferase MptB"
                     /protein_id="WP_133851449.1"
                     /transl_table=11
                     /translation="MPAFPLTRAAIVGFGGSLLTAFGAAGAGGTPVGDGPLVGTPFEAL
                     RYGHGQMLAVGCVYAGVLVLAVAWVQLGIAVRHGAIDTAGMFRTSALWALPLLTCPPLF
                     SRDLYSYVAQGALAAHGLDPYTTGSSRLPLALHENVHWVWQDTPTPYGPVHIILTRAIA
                     SVTGENVVAGVLLTRLVFAAGLVLLAAALPGICRVVGTRPEFALWFAVANPLMLVLVLG
                     GGHNDMLAIGLLAAATLFVLRRNHFAGLALLALAVAVKATMLVALPFLLWSVSRRLHLA
                     VGKALAAMVPTFVVATVLAGHGFGWVQALGSTSLIVNWMSLPTGLGEVLGQALSLDWGD
                     RELLIECMRAVGMATLAVLVVVLWWRSRSGAPAVVLRNATLALTLAAILLPATLPWYFS
                     WAIALGAVLPWSAVSWTRARLACASAGAVWLVVCDYPTGEAAVYDWNYVGITLAIAALI
                     GAAAVYLEPERVEVAV"
     gene            15956..16852
                     /locus_tag="EV186_RS22810"
                     /old_locus_tag="EV186_10425"
     CDS             15956..16852
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332687.1"
                     /locus_tag="EV186_RS22810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_10425"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_133851450.1"
                     /sec_met_domain="phytoene_synt (E-value: 3.7e-113,
                     bitscore: 372.8, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.5e-66,
                     bitscore: 220.3, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTELSAAYAACREINAAHGRTYYLATRLLPASRRPAVHALYGFAR
                     LADDIVDVVDTPGADPAARLDELATAVKDAFAGRPSTPVLLALADTVRRYGIDQGLFDD
                     FLASMRMDLAVTGYATMADLSAYMRGSAAAIGLQMLPVLGTVGPEEPARAPARALGEAF
                     QLTNFLRDVGEDLDRGRLYLPADELAAFGVDRDRLVWARSSGKPDPRVRRAIAHLVGYT
                     RAVYRRAEPGIALLRPESRPCVRVATTLYRGILDEIQDAGYEVLNRRAVVPLGRRLRVA
                     GTGLLRARWHDLQNPRA"
     gene            complement(16834..17199)
                     /locus_tag="EV186_RS22815"
                     /old_locus_tag="EV186_10426"
     CDS             complement(16834..17199)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020657740.1"
                     /locus_tag="EV186_RS22815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_10426"
                     /product="DNA-binding protein"
                     /protein_id="WP_133851451.1"
                     /transl_table=11
                     /translation="MSSIPTADDVLDPQVDVLPVEEVATALGVPVSRIYQSVRDGHLIA
                     MRRAGQLCMPAVLIDGSEPVKGLSGTLTLLRDAGYTPTEMLRWLFAPDESLPGTPIDAL
                     RSNRGREVKRRAQALGF"
     misc_feature    complement(17190..17205)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.61"
                     /tool="antismash"
     gene            17295..19448
                     /locus_tag="EV186_RS22820"
                     /old_locus_tag="EV186_10427"
     CDS             17295..19448
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009943830.1"
                     /locus_tag="EV186_RS22820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_10427"
                     /product="PASTA domain-containing protein"
                     /protein_id="WP_243754219.1"
                     /sec_met_domain="Pkinase (E-value: 3.9e-48, bitscore:
                     159.7, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEDRGSSLIGTLLDQRYRIDGLLARGGMSAVYRAQDTRLDRPVAV
                     KVMDERFVADKSFVDRFEQEARSAARIHHPNVVAVHDQGVDGDKIYLVMELVDGGTLRD
                     LLESGPLSVELACAILEPVLAALGAAHRSGLVHRDVKPENVLIGRTSSGGSVVKVADFG
                     LVRAVSGSSMTQGSVIMGTVAYLSPEQVTTGTATARGDVYSAGIVLYEMLTGRPPYVGD
                     TTLSVAYRHVNDDVPAPSTVAPTIPAAVDELVVQATRRDPADRPMDADEFLSALRRVCS
                     ALAIRPVRVPIPEHENEKTMPVSGAIAAGAGSAQGSVQGSLDGALATQVTGQATSVVAR
                     PKAVHTVGIGPQGTRTMARSQFDALTERRPPVRPQPMRPNPPNYPPPNGFPPPGDDYDD
                     GYNGYDGYPETGAQPEQRGRRKGLLITLIVVGALLLGAGGTATWWFTSGRYSTVPSVAG
                     KTQEEALKEISDAHLTPRLADKPRLDNKIPKGIVISTDPSGGRLLRGTTVTLVVSGGKP
                     VVPNIGQGADPKDAAKALADVQLVAKKDPAKDEYNPNVPQGKVIRVDPRPGSALDIGTD
                     VLLVLSKGPEPKPVPDVAGMDHDQAFQTLQTAGLTPVDGPAEFSADVDGGKVIRTDPPA
                     NTMLDSSNTQITVISSNAVTVPDLGQQLVTDAQKALTDLGLTVQVVNVSGQAGNPGSRV
                     YAQSAPPGSRVQPGSQIVLTAFP"
     gene            19550..19765
                     /locus_tag="EV186_RS22825"
                     /old_locus_tag="EV186_10428"
     CDS             19550..19765
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009075010.1"
                     /locus_tag="EV186_RS22825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_10428"
                     /product="hypothetical protein"
                     /protein_id="WP_133851453.1"
                     /transl_table=11
                     /translation="MIGSRGRVTGTIGPGLIGEVLISVRGGVEAFYAYPADPDTKITIG
                     TQVLVVDFDEPNTVYVEPWRPTRLTG"
     misc_feature    complement(19785..19799)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 19.16"
                     /tool="antismash"
     gene            19810..21288
                     /locus_tag="EV186_RS22830"
                     /old_locus_tag="EV186_10429"
     CDS             19810..21288
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020657737.1"
                     /locus_tag="EV186_RS22830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_10429"
                     /product="flotillin family protein"
                     /protein_id="WP_133851454.1"
                     /transl_table=11
                     /translation="MSSTLLVVIGGAIVVLIVLFALLKAFYKVAEPNEALIISGLGINQ
                     QRTGTEDSLKFKIVTGRGVLVLPGFQTARRLSLDTRGANLEVSCVTKQGLPVTVRAVVI
                     YKVGDDFSLIANAARRFLDQQDGMNSTIHELFSGHLRSIVGGLTIEDMIHNRDALTGEI
                     RQSSAAEMIKLGLVVDSLQIQEIDDESGYILNLGKPHAAAVAASARIAEAQRDQEATQA
                     EQIAAAEKAGAIRESQIKQAGYTAEVDQAKAKASQAGPLAEATARQEVVVQETRAAELE
                     AELSEQRLQSQVRKPADARAYETRTTADAERDAQIARAQAQAKETELRAAADATKVKTA
                     AEAEAQATRARGEASAAATKATGLAEADSARAKGLAEAEAAKAKGLAEADAIKARSDAL
                     AENQEAVVAQQLAEKWPEIVAAGAQALGNIDHMVVLNGADGVSDIFAKALSLGGTGLGL
                     ARQLMEGMKVKDTDTPPTNGVVPTSLTGTETKID"
     gene            complement(21338..22123)
                     /locus_tag="EV186_RS22835"
                     /old_locus_tag="EV186_10430"
     CDS             complement(21338..22123)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EV186_RS22835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EV186_10430"
                     /product="hypothetical protein"
                     /protein_id="WP_133851455.1"
                     /transl_table=11
                     /translation="MAALLDPERGTLPDGYVTGTGPDDWPAFFDLVRTRGWDAEPGHYE
                     EVHHVRPVPGMELNFFRRDGEGITFDVDLREVRDQERLDVLCAVLADLGRAFGNDVRLV
                     PEGGSDWELLRYDAGADRIVVPSVDVPSWAEFGDFLRAELPRADGLLVRLGPRQWQGLL
                     DRVTEAGWAVDREDLDGVVRYELRAKPHLGLECYPGESDVLVAPILPEVTEESFAEFCV
                     LLRAIGRAAGCDIEFVPEGGEAPMLRYRGWDESITAELV"
     gene            complement(22141..23529)
                     /locus_tag="EV186_RS22840"
                     /old_locus_tag="EV186_10431"
     CDS             complement(22141..23529)
                     /EC_number="2.5.1.54"
                     /GO_function="GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015800237.1"
                     /locus_tag="EV186_RS22840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_10431"
                     /product="3-deoxy-7-phosphoheptulonate synthase class II"
                     /protein_id="WP_133851456.1"
                     /transl_table=11
                     /translation="MNWTVDVPVDTLPELPPLPPDMRSQLDDALARPAAQQPEWPDGEH
                     VRQVRTVLESVPPVTVPSEVDRLRDRLADVANGEAFMLQGGDCAETFADNTEPHIRGNI
                     RTLLQMAVVLTYGASMPVVKVGRIAGQYAKPRSNGTDALGLPVYRGDIVNSLVATPEAR
                     VPDPSRMIRAYANAGAAMNLLRALTGAGMASLARVHDWNKDFVRTSPAGERYEALAKEI
                     DRGLRFMSACGVTDRSLDSTEIFASHEALLLDYERAMLRLDKESGQPQLYDLSSHFLWV
                     GERTRQLDSAHIALAELLSNPIGVKIGPTTTPEQAVEYVHRLDPHDTPGRLTLISRMGH
                     TKVRDVLPPIIEKVESTGHRVIWQCDPMHGNTHESSTGYKTRHFDRIVDEVQGFFEVHR
                     RLGTHPGGIHVELTGEDVTECLGGAQEISEEQLGGRYETACDPRLNTQQSLELAFLVAE
                     MLRS"
     misc_feature    complement(23524..23539)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.49"
                     /tool="antismash"
     gene            23631..24665
                     /locus_tag="EV186_RS22845"
                     /old_locus_tag="EV186_10432"
     CDS             23631..24665
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF022646.4"
                     /locus_tag="EV186_RS22845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_10432"
                     /product="DUF2891 domain-containing protein"
                     /protein_id="WP_208115758.1"
                     /transl_table=11
                     /translation="MTSTLDPETAAALLDSAIANVQRDYPVHWTHVITSPEDLRTQREL
                     HPVFAGSLDWHSCVHQTWLAVRLLRVNADLPGAAKAREVLDGLLTPENCAVEADFFRGG
                     LGAWWERPYGWAWLLTLDAELRTWSGGAQWSAALAPLGAVVRDRWLNWITGARLPVRVG
                     THGNTAFATMLVLEAALATGDDELASACRAAATRWYLDDKGYGGFEPDAADFLSPALTE
                     ADLLRRVLPASDFGAWLSAFVPDLAEARWARLREPATVDDPADPYGAHLAGLALSRSWA
                     WRGIGESLPAGHPYASLAAAAAETHAELGWQYVFGYGYEGAEHWLGTFAAYLDIGAFKD
                     RVTL"
     misc_feature    23667..23669
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    23835..23837
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    23853..23855
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    24922..24937
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 20.99"
                     /tool="antismash"
     gene            24959..25093
                     /locus_tag="EV186_RS40555"
     CDS             24959..25093
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EV186_RS40555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_279538317.1"
                     /transl_table=11
                     /translation="MELGELYSTVAQMRQLELKLLDDISQIEWKESGYPQLGPVTISV"
     gene            complement(25122..26402)
                     /locus_tag="EV186_RS22850"
                     /old_locus_tag="EV186_10434"
     CDS             complement(25122..26402)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1130: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008258297.1"
                     /locus_tag="EV186_RS22850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_10434"
                     /product="IS256 family transposase"
                     /protein_id="WP_133851458.1"
                     /transl_table=11
                     /translation="MSENQADPAAETAAQRLSAALDPSAIDALLADAKAAGTPIDGVDG
                     LLNQMTKAVLERALQTEMTQHLGYDRDDPAGVGTGNSRNGTSRKTVSTVNGPVTITVPR
                     DRNGEFEPQIVPKRARRVGQIDELVLSCYARGMSTRDIEAHLFEVYGVTASRELVSNIT
                     DVVTDEIEIWRNRPVDEVYPIVYVDGIRTKVRDKGAVAIKSAHLVIGVDVDGRKHALGC
                     WIAETEGAKFWHSVLTQLRNRGLRDILIACCDGLAGLPDAITAVFPDTVVQTCVVHVIR
                     NAMRFVSYQDRKKIATSMRAIYTAPTVEAADLALKDFDTEWGRQYPGVTDVWRRAWNEF
                     IPFLDYPVELRRIVYTTNAIESINFQLRKITKTRGHFPSDEAAMKLIYLGLRNISSKRG
                     GESGTGTHGWKTALNTLVVLFPGRLPL"
ORIGIN
        1 cgcgccgcgc gatccgggtg cgcatcgcgg gcgaggaacg tttcctggcc atcgaggacg
       61 ccgggcgggt ccgcgacgcc ctgggcgttg ccctgccggt cggtgtcccg gaggccttca
      121 ccgagccggt ggccgacccc ctcggcgacc tgctcgcccg ctacgcgcgc acccacggtc
      181 ccttccccgc ccatgacgcg gccgaacggt tcggcctggg cgtggcggtg gtgaccggcg
      241 tcctggaacg gctggccggc accggtcgcc tggtccgcgg cgaattgcgt ccgggcggca
      301 cccacaccga gtactgcgac gcggacgtcc tgcgccgcct gcgccgcggg tcgctggctc
      361 gcctgcgcgc cgaggtggaa ccggtcgaac cggcagcgct gggccgattc ctgccgtcct
      421 ggcacggcat cggcaggcga ttgcggtccg caccaaccgc ggacgatgtt ctgtccgttg
      481 tggagcagct ggccggcgcc ccgctcccgg cgagcgctct cgaatccttg atcctgcccg
      541 cccgcctgcc gggctactcc cccgccctgc tggacgagct gaccgcagcc ggcgaggtca
      601 cctgggccgg gtgcggcgca ctgggtgcgg gcgacggctg gctggcgctg gcgccgggcg
      661 acctggccga cctggtgctg cccgaggtgg ccgagtccgc accggacacg ccccggcaca
      721 gagccgtgct gtccgctttg gacggtggcg cgctgttctt ccgccagctg gccgaccgcg
      781 cgggcatgat catgatcgaa cacggcgagg aaccgccgaa cgaccaggac ctggtcgcgg
      841 tcgtgtggga tctcgtgtgg gccggcctgg tcaccaacga caccatgacc ccgttgcgtg
      901 ccttggtgtc cggccggggc gcgacccacc gcccgcgcgc cgcccaacct cgcggccgct
      961 atgcccgcat gcgctcgagc cgggcggtga tgcccagccg caccggtccg ccgacggccg
     1021 cgggccgctg gtccctggtg cctgaacgcg agccggacgc cacccgccgg gcccatgccc
     1081 gggcggagac cttcctcgaa cgccacggcg tgctgacccg aggcgcgttg gacaccgagc
     1141 gggtcaccgg cgggttcagc ggtgtgtaca aggtgctgcg ggcgatggag gagtcgggcc
     1201 agctgatccg gggttacgtg gtggagggtc tgggtgccgc ccagttcgcc gcccgcggcg
     1261 cggtcgatcg cctgcgcgcg gtgtcccgtt cggacactcc cgacaccctc aacccgcact
     1321 cccccaacgc gaagggttcg tccgcggtgg tcctggccgc cgccgacccc gcccagccct
     1381 acggtgcggc gcttccctgg cctcagccgc tgggcgacgg caagcaccgc ccggcccgca
     1441 aggccggggc cctggctgtg ctggtggacg gcgtccccgc cctctacgtg gaacgcggtg
     1501 gcaagtcact cctgtcgttc accgacgacc aggaagtcct gtcgacagcg gcgcacgccc
     1561 tgtcccgagc cgtccgcgaa ggctggctgg gccagctggc cgtccagcga gccgacggcg
     1621 acgacatccg gacaagcgcc cagaacgccg ccctggccga aaccctccgc gaggccggat
     1681 tccgcgccac ccccaagggc ctacgcctgc gcgcctgacc cggagcaatc acccgagcgc
     1741 cggtgagcac ccagcggtgg caaccggtca aagaatgcag aactcgttgc cctgcggatc
     1801 ttccaacacc gcccacggca catcgccctg cccgacatcc acccgacctg ctcccaaccc
     1861 caccaaccgc tccacctcaa cgccacgcac atccaggtgg acccggttct tccccacctt
     1921 gggatcgttg gtgcgtaaca gttccagcca cggcccccgc ccgtccgggg cacgcagcga
     1981 cgcaaaccgc ggctccgcgc gaacgacctc ccaccccgtc gccgtcgccc agaacggggc
     2041 cagggccgcc gggtccggcg tgtccatgac gatcgaggcc aggcgaccgg atcccgcata
     2101 aacggcccgg tgctcgagca cgcagaactc gttgccttcc gggtccgcga gcaccaccca
     2161 cggcacgtcg ccctggccga tgtcgacgtg ggtggcgccc gccgtcaacg cccggtccac
     2221 cagctccgcc tggtgttccg ggccgttgct cgccaggtcc aggtgcacgc ggttcttacc
     2281 gcgcttcggc gaagcgaccg ggacgaagac caggtccaac gtcgcgccgt cagcggacgg
     2341 cgccacgacg tcgacctcgc cttcgggctc ctcgcgcacg aaccagccgg acagcatctc
     2401 cgaccagaac tcggcgaggt gcgcaggcga agcggcatcg acaacgacgt tgaccagcat
     2461 gtcccggacg gtagccggga ccaccgacac tcagcgcgtc gccaaccgca gcaacgccca
     2521 cagctggccg accgcgtcca tgccggtgaa cgtcaggtcc cgccggccat cgggctgcgg
     2581 gtcaccccat gggctcttgc gaccccacaa ccacaggtac aacgcctgcg gattgcgtcc
     2641 gacgaccgtg ccgttgaccg actcgcgggc gtggtcgagg tccggcatcc accacgccgc
     2701 ggtgtccacg ccacgcggcg cccgcaccat ccaaccgccg tccacgcctt cgcagcgcac
     2761 cgtcaacacg gcgtcttgcg tgttgcggat gcccagcacg cgcagcttgg acacgaacca
     2821 ctcggtcagc acctcgtcgg caccgtcgag cgcgacgtcg tcgtcgaccg cggcgatcgg
     2881 gagccccgcc gcgccctgca cgtcgatgcg gtgcacggtc gtctcgtgcg cgagccggcg
     2941 gatccagaac ccgtacgtct tgtccttgga ccacgaggcg cacgggtcgg cggggtcgtg
     3001 cgcggcgagt tcggtcatca cgtcacgcag accgatccgg tagaactcca gcaacgactg
     3061 gtccggcccc ggctcccgct gccactcgac cggcttgcgc ccggtggtga tccacgacag
     3121 cgacgcccgg tacaacgcac cgaggtgccg caccgtctcg cccagcgtca gccccgggca
     3181 gtgcggcacg cgggcgcgcg agggcgcgtc gctcgccacg ccggcgagca cgcctgcctc
     3241 gatcgccagc acctgcaaca gctgctcgtg gtccagccgc ggggtcatgt cgatgagccg
     3301 tgcacggcac ggcccaccag ttcgatgaac tgcccggcct gccggacgag gtcgtcggcc
     3361 gcccgcgcgg tgacgtgccg ggtgatgccc gcctgcacgc gcgcccgggt cgccgaaccg
     3421 gcggcgaaga acgcggccca ctcgccgaac tcgggggcca ccgacgacag cagcgtccac
     3481 acgctggtcg gccgcgcccg cccccggtgc gggcgaccac gcaacgcgag catggcggcc
     3541 gcggcccgca gcgcggacag gtacgcggcg gcgaaccgct gcccggcgtc acgctcgagt
     3601 tcggcgtcgg ccaggccccg ttcggcctgg gcgagcaggg ctcccgcgga ctcgctgtcg
     3661 ccggggaacg gtacgtaccg ccgaccggcg ccgagcgtgg gtgcggggaa gtcgagtgtg
     3721 gtggacatcg cggcctcctg gcggtcgggt caggcatgct gggggtgcca cgcatgcgct
     3781 cgccgtgggg agccggcggg cctggcggtg aggcgcttcc cccaccccac cgccaggcga
     3841 ctagctcgaa catctgttcg aacaagtcca gcataactcg tcgccagagc gggctcaacc
     3901 cacacccggg tgaccctgat caggccggac gaagcaccgc ccgtaccccc ggctcgacca
     3961 gccggcggta cgccgcggcc agccacgcgg cgtcgtgcgg gaagccgttg tcgaccgccc
     4021 agcccagcag accgagcgtc gtgctggtgc agaactcgac gaccacctcg gccggcacca
     4081 cgggcttgcc caggcacaac tgcgccatga gcagttcggt cagcatccgc cgcaggtggc
     4141 gctggacgac ctcgccgcct tgcttgccgc acaacgcccg gaacgccggc tgccgctcgt
     4201 aggcgaagcg gaacaaggcc tcggcgggcc gcgccggatc cgaggccacc gcgccgagtt
     4261 ccccacgaag gtcctcgctg agcgcgtcga acgccgcgag cagcaacgct tccttgtccc
     4321 ggaagtgcgt gtagaaggtc gaccggccga cgtcggcgcg gtccagcacg tcctgcacgg
     4381 tgacccggtc gtagcccttc tcgaagatca gcgcgaagag cgcctcctgc agcccccggc
     4441 gggtccgtcg cacccggcga tcctgttgga ccacaacgcc tcccgaacac ttcgcggcaa
     4501 ctgtccggaa ccgcacaccc cgccggtttt ggttgttgaa cccctacggc agaaccgaac
     4561 agagtgttca gcatcggacg tcatgttcac aagaggaggg actccgatgc cgttctccat
     4621 ctggttgctc gtgctcgtgg gagcgcttgg catcccggcc gtgacctgcg cggcgctcta
     4681 ccgcggcgcc ctggtcgtcg gcagatcagg cccggacgca cggcgcatcg ccgtgctggc
     4741 aggcgtcgcg tgggccgcgt ggaccgcgct catctgggcg ttggcggccg ccgggctgtt
     4801 ccacctgccg ccgacccagc cccagccctg gatcccggtc gcggtcgtcc tcggggtggt
     4861 catcgtggtc gccgcgagca ggcgcccggc cgcccgcgcg atcctcgccg atcccggagc
     4921 gctgcgcctg ctggcgtggc cccaagtgct gcgggtcgtg ggcgtggtgt tcctgatcgc
     4981 gatggccatg ggccgaatcc ccgccgcgtt cgcgctgccg gcgggcatcg gcgacatcgt
     5041 caccgggctg gccgcgccgt tcgccatccg cagcggccgc gtgctgtggc tcaacatcgt
     5101 cggcctgctc gacctggtcg tcgctttggc gctgggtctt ctgaccgggg tcggccaggg
     5161 tcagatcctc gccgtgagcc cgtccagcga actggtcagc acgctgccgc tcgtcctgat
     5221 cccgctggcc gccgtgccgc tggccatcgg gctgcacctg gtgagcatga ccaggatggg
     5281 cgcgctcgcg cgggaaagcc ggaggcgcca cgtggtcgcg gcgtgatctg atggtcgggt
     5341 gagcagtttc gaccaccctt ctgtcagcaa ggtcgccgcg atcctgcgtg aggcgggcgt
     5401 caccgacggc gccgaccgga tccggatcct ggacgacgag gcgcgcacgg cggcgctggc
     5461 cgcgcaggcg ctcggcatcg aggtcggcgc gatcgccaac agcctcgtgt tcgtcgcgca
     5521 cttcgccgac ggccacacgg aaccgttgct ggccttgact tccggggcgc accgcgcgga
     5581 caccggccgc ctcgccgcgc tggccggcgc cgacaaggtc accaaggcgc gagcggagtt
     5641 cgtgcgggag cacacgggtc agccgatcgg cggcgtcgcg ccggtcggcc accccgaacc
     5701 ggtgcgcacg gtggtggaca accacctcgc gacctacccg gaggtctggg ccgcggcggg
     5761 gcacccgaag tcggtgttcc cgaccacgtt cgccgagctg gtcgcgttga ccgggggcac
     5821 ggctgcggac gtcgcggcgg aggaggatca tcttccttcg tgaccgcggc cgagtcctcc
     5881 agccccgacc gcctcgctga gctgtccgcg caggatctcc gcgcgcggct gtccgaggcg
     5941 ctggacttgt atgtgaccgc gatgcgctac ccgaagggca ccgcggagca acgcgcgccg
     6001 atgtggctgg cgcacatgat gcgcacgggc tggcgctgca tcggcgcgtt cgacccgaac
     6061 ggcaacctcg ccggcatcgc ctacggctac cgcggctcac ccgggcagtg gtggcacgag
     6121 caggtgcgcc ggggcctgat cgaacgctcc ggcccggccg cggccgacca gtggacgctc
     6181 gactacttcg agctcaccga gttgcacgtg cgccccgacc ggcaaggccg gggcaccggc
     6241 gagaacctgc tgcgtgcgtt gctcgccggt gccaccgagg gccgggtgtt gctgtcgacg
     6301 ccggaaggac cgtccagggc gtggcggctc taccggcggg tcggcttcgt cgacgtgttg
     6361 cgcgactacc agttcagcgg cgacccgcgc ctgttcggcg tgctcggggc gaccctgccg
     6421 ctggcctgag ggccggtgcc ggacggtcgc gcgccgcgac cgctcagagc cgggcgagct
     6481 gctcgcgcag cgtgtccagg cccatcgaac ccagcgccag cgcctgctgg tggaaggtct
     6541 tgaggtcgaa cgcggcgccg tggcgggcgc gtgcctcctc gcgggcctgc agccacagcc
     6601 gctcccccag cttgtacgcg ggcgcctggc ccggccagcc gaggtagcgg tcgatctcgt
     6661 cggtgacctg cgccgggtcg gtgatcgtcc ggttcagcat gaactccagg cccagctccg
     6721 gggtccaccg ctcgccctcg tggaacccgg tgccccgcgg gatctccagc tccaggtgca
     6781 tgccgaggtc gacgatgacg cgcccggccc ggaacaggtg ggcgtcgagc atgccgaaga
     6841 ggttcgcgtc gtcctcgagg tagccgagct cgcgcatcag ccgctccgcg tagagcgccc
     6901 agccctcgcc gtgcccggag acccagcaca gcatccgctg gaagtcgttg agccgctccc
     6961 gctcgtacac cgcggtcgcg atctgcaggt ggtggccggg aacgccctcg tggtagacgg
     7021 tcgagacctc gcgccaggtc gagaagtcct cgcggcccgg ttcgaccgac caccacatcc
     7081 ggcccggccg ggagaagtcg tcgttgggcc cggtgtagta cgcgccgacg cccccgccgg
     7141 gcggcgcgac caggcattcg agcttcatga gctcgtcggg caggtcgaag tgggtgccgc
     7201 gcaggtcggc gagcgccgcg tcggagagct gctgcatcca ctgctcgagg ccggccttgc
     7261 cggtgacgcg gtagcgcggg tcggcgtcga gcgccgcggc cgcctccttg agcgtcgcac
     7321 ccgacttgat ccggtcggcg acctgcttca tctcggtctc gatgcggctg aactccgccc
     7381 agccccactc gtaggcctcc tgcaggtcca gccgggaccc gaggaactgc cgcgaccaca
     7441 tgcggtagcg ctcctcgccg accgcgtcct tctccggtgc cttcgcggcc agttcgtccc
     7501 gcaggaagga cgcgaaccgg gcgaacgcgg cggaggcgtc cccagcggcg gcggtcagct
     7561 tcttgcgcag cgcctcgtcc tcggtgttcg cctggtcggc cagcgcggcg aagaacgcct
     7621 tctcgtcact cgccccggac cagacgtcgc actgctcggc gaccttggtg acctggcgca
     7681 acgccaccac cttgccgcgc gcggccgcgt accgcatcga ctcgatgacg ccgtcgaccg
     7741 cgtcggacac cgccgacatg cggccggcga tcacggccca gtcgtcggcg gtctcggtgg
     7801 gcatgaggtc gaagatctgc cggacgtggt gcaccgggct gccgatgacg ttcatgtcgg
     7861 cgtgcgccca gccgctgtcg tagatctcca gctcgagccc gatgcgctcg gcgaacacgg
     7921 cctgggccac ccgctcgccg tcgtcggcgg gggtggcggc ggtgatccgg gcgagggcgg
     7981 cccggccgag ctccgcgcgc tgttcgagcg cttccgggga gaagtcggtc atctccgcgt
     8041 cgtggcccgg gaggccgacg gcggtcgcgg tgagcgggtc gagcgcggcg tagtggccga
     8101 cgaactcgtc gctgagcgcg tggatggtgc gatccgagtg ctggtcttct ggcatggccg
     8161 cgaacctacc cgcgtcgcgg cgcgccgtcc ctggcctttt cgcgctgctg gcaggatgaa
     8221 cgcgtgcgaa cccgaccccg caggtggctg tccgttctcg tgctcggcgt gctgacgatg
     8281 ctctgcctct cgggctgcgt acgggtacga gcggcgatgg cggtgtcgcc caacgacctc
     8341 gtgtccggcg agatcgtgat cgccgcgcag ccgacccgcg ccggggacca gggaccggag
     8401 ctggagatcc cggacgccgt gaaggcgcgg accagcacca aggcgtacaa cgtggacggt
     8461 tacgtcggca acacgctgag cttccacgac ctcaccttcg aggaggtgcg tgagctcagc
     8521 tcgagcatca acccgaactc gcagcacttc cagatgagct tccgccgctc cggcgacctg
     8581 gtgaccatgt cgggttcggt ggacctgacc gggttgccca ccgacaaggc cgacgtgcag
     8641 atcaagctcg cgttccccgg ccgggtgacc aagaccgacg ggatcgacga ggacggcgcg
     8701 atcacgtgga agcccaaggc tggtgaggtc accgagttca ccgcgaccgc cgagtactcg
     8761 accaagggcc agagctcgtg gacgcgctgg gtgatgatcg tcgcggccag cgcgatcggc
     8821 gtggccctgc tggtggcgat cctcgcttac gccgcgcggc gagtcagcct gcgccaagtc
     8881 cagtagtcag gcccgcgtcg ggagcaaccc caggcgggcc accacttcgc gggtggcctt
     8941 cgagcggttc atcgtgatga agtgcagccc cggcacgcct tcggccagca ggcgttcgca
     9001 gaggttcgtg accaggtcga tgcccgcggc ccggaagccc gccgggtccc cggccagcgg
     9061 gtccatccgc tcggcaatcc acgcggggac gtcgacgccg gccagttccg cggtcttgtg
     9121 cagggtccgg accgtggtca acggcatgac gctgggcagc agcagcgcgt ccgggtccac
     9181 agtggccacg cggtcgcgca ggcgcaggaa gtcgtccggc tcgaagaaca gctgggcgat
     9241 ggcgaagtgc gcgccggcgc ggaacttggc gatcaggtgg cgggtgtcgg tgtccaggtc
     9301 cgccgaacgc gggtggccgt aggggaacgc ggccacgccg acgcagaagt cacccaggga
     9361 acgcaccagg cgcaccaggt cctcggcgta gttgaggccc tgcgggtggg cgatccagtc
     9421 gccgtacggg tcgccgggcg ggtcgccgcg cacggccagg atgttgcgga cgccgacggc
     9481 cgcgtaccag ccgatcatgt tgcgcagctc ggccaccgag tggtccaccg cggtcaggtg
     9541 ggccatcggg gtcatcgtgg tttcctcggc gatcagccgg gtcgcctcga tggtgccgcg
     9601 ccggctcttg ccacccgcgc cgtaggtgac cgagacgaac gccgggtcca gcgactcgag
     9661 ctcacggatc gcccggccga ggatctgctg gtcggcctcg tcccgcggcg ggaagaactc
     9721 gaccgagaac accggcctgc ccaccgaaat gcgctcgagg acggaggtca tgggcccgag
     9781 ggtaacggag cgtccaggaa ctgggacaag cgtccgaaag gtggacgctc gctccggcgg
     9841 atggccgggt cgcgaactcc gccgggcgtc cctggaccgg tcggcggggt taccggaccc
     9901 ccggtcggcc gtgatcggcg acacggcgga ccatgtaggg gtgcacacgg cgtccgaccc
     9961 gaagtcgatc gacgacacgt tgcccaccgc ggtccaggac gtgctggcca cgtacctcgc
    10021 ggccaagcgt gcccagctga cggcggcgga gccgtcggcg ggcgacgccg tggacgcgct
    10081 ggccgacttc gtgctcggcg gcggcaagcg catccgcccg actttcgcct ggtggggctg
    10141 gcgcggcgcc ggtggcgcgg ccgacggcgc cgaagccgag aaggtgctga ccgcgatcag
    10201 cgcgctcgag ctgatccagg gctgcgcgct ggtgcacgac gacctcatgg acgactccgc
    10261 gttgcgccgg ggcaagccga ccgtgcacgt cgacttcgcc gggcggcacc gggcggccgg
    10321 ctggcacggc gaccccgaca agttcggcgc cgcggccgcg atcctcatcg gcgacctcgc
    10381 gctcgcgtgg gccgacgacc tgttcaccga ggcggggctc accgccgctc agctgctggc
    10441 cgccggcccc gcgtggcgcg ggatgcgcgc ggagatgctc gccgggcagt acctggacgt
    10501 gctcacccag tccgacggcg gcgcgccgct gcccccggcc gaggccgcca tgcgggtcgc
    10561 ccgactcaag accgccgcct acaccgtgga gcgcccgctg cacctcggcg cggcgctcgc
    10621 cggggccggt gagcggacgg tcggcgcgct gcgggcgttc ggcggcgaca tcggcgtggc
    10681 gttccagctg cgtgacgacc tgctcggcat gttcggcgac acggccgtga ccggcaaacc
    10741 ggcgggcgac gacctgcgcg agggcaagcg cacgctgctg atcgcggtgg ccgtcaccaa
    10801 cgccgagcag gccggccggg acgcgaccgt cgagatgatc cacgaggcgc tcggcaaccc
    10861 gaagctgtcc gccgacgacc tcgaccgggt gcgcgaggcg ctggtcgacc tgggcgcggt
    10921 cgccgaggtg gaggcgcgca tcgagcggct gaccgggacc gccctggagg cgctcgcgtc
    10981 ggccgaactc gccgcgcccg ccggggaccg gctcgcggcc ctcgccgacg cggcgacccg
    11041 ccggtcgtac tgatgcgcac ggtgccggga cgcaccgacc acgttgtggt gatcggcgcc
    11101 gggctcgccg ggctctccgc cacgctgcac ctgctgggcg ccggtcggtc cgtgacgttg
    11161 ctcgaggcgg ccgacgggcc cggcgggcgc gccgcgagtt ccttcgtggg cgggcagcgg
    11221 gtcgacaccg gcgccacggt gctgaccatg cccgagtacc tcgacgacgc cctcaacgcg
    11281 gtcggcgcga agctggccgg gcgggtcgac ctcgtcccgt tgcaccccgc gtaccgggcc
    11341 catttcgccg acggggagac gctggcgttg cacaccgacg ccgacgcgat ggccgcggag
    11401 atccgccggt tcgccggacc acgcgacgcc gatggctacc tgcggctgcg ccagtggctg
    11461 accaaactct atgtggcgca acgggatcgg ttcatcgcga ccaacttcga cagcccgctc
    11521 gacctgctcg gcccgcagct ggcccggctg gtcgcgctcg gcgggttcgg ccggctgagc
    11581 ccggcgatcg cccggttcct gcccgatgag cggctgcggc ggttgttctc gttccagtcg
    11641 ttgtacgcgg gcgtgccgcc gcagcgcgcg ctcgccgcgt acgccgtgat cgcgtacatg
    11701 gacacggtcg ccggggtcta ctaccccaag ggcggcatgg gaacggtggc ctcggcactc
    11761 gcggacgcgg cggtcgaggc cggggccgac gtgcggtacg cgacgacggc ggcctggctg
    11821 gagcgggtcg gcgggcgggt gcgtgcggtg cgaacgtcga cggggcaacg gatcccgtgc
    11881 gatgccgtgg tggtgaccgc ggacctgcct gccgcgtatc gcttgctggg cctgacaccg
    11941 cggcgcccgg tgggactgcg ctggtcgccg tcggcggtgg tgatgcacct gacggtggat
    12001 cacgagtggc cggcgctgga ccaccacacg atcttcttcg gccaggcgtg ggaccggacg
    12061 ttctcggaga tcaccagcgg ttccctgatg accgacccgt cgttgctggt gaccaatccg
    12121 gccgcgaccg atccgcgccc cggcggcggc cgaccgctct cggtgctggc accgtgcccg
    12181 aacctggcga ccggccggat cgactggcca cgcgtcggcc cggcttaccg cgacgaattg
    12241 ctgcgcacgc tggccgggcg cgggctcagc gggatcggcg acgccgaggt gcacgaggtg
    12301 gtcacgcccg cggactgggc cgcgcgcggg atgggcgccg ggacgccgtt ctcgctggcc
    12361 cacacgttcg cccagaccgg gccgttccgg ccacggaacc tggtgcgggg cgcggagaac
    12421 gtcgtcctcg ccgggtgcgg gacgacgccg ggcgtgggga tcccgccggt ggtgctctcg
    12481 gggaagctgg cggcggcgcg gatcgccgac tgagccgttt cacctgatcg agtgacgaac
    12541 gtgcgttcga ggttgtggca cactggtcga acacggaacg taccttgtca actacacagt
    12601 ggcactactt ctgatcgcag gccacagcct ggcctgcggg gcaacgcttg gccgacgcac
    12661 ggtagtcggc gatcagctgc tgctgcgccg cataggcggt aggggcgtcg ttggccgtgg
    12721 tgacctggtg gaacgcgcac atccggccgg tcgcggactg gcacgcgtcc agctgctgcg
    12781 cggcctggtc ccgccagtac ccgctggcca cgacgccgta cttccacatg tcccgcgcgt
    12841 ggccgccctt ggcgtggtcg atggcgtaga ccacgtacgc accgttcttg gccggcttgg
    12901 cgggcgcctt ggcggtggcg tgcgcgtgca cggccttgcg gtcgggcggg tcggccaggc
    12961 tcaccgccga ccactcggcg cggtacgggt gctgaccggg caccgagtgc gcgttctggt
    13021 agaacgccgt ccactggggt gaggtgatcg tgcaggtggc gctgatctgc tcgccggggg
    13081 ccaccagacc ggtctgggtg tcgcagcggc cgagcggctt gccgtcgccg atccagtcgg
    13141 ccgacaccga cacccgcacg gcgaccttgg cgccgttggt caggtcgacg atcaccgcac
    13201 aactcgcctg cccgcactcg gcgaaacggt gcgagccctc ctcgacgggc gtgatcaggt
    13261 cgaccggggc cgcgagggtg gccgcctgcc cgtcgacgtc gcggtagagg ctggggagcg
    13321 cggcggtcgc gtcggtgaag gcgaggtcga ggtcgcgggc ggccgacggg ccggcctggc
    13381 ccaccgaagc gagcttggcg ccgaccaccc ggtggggcgc ggtcggggtc acgaactcgg
    13441 taccggcgct caggtcgatg gcgagcgcgt ccaccccgcc gaccttctgg cgccggttgg
    13501 cctccggcgg ctgctgcgcg gtgggagccg ggccgtcggc gagcagctgg gcgagcgcgg
    13561 gtgggctgaa caggtcctcg atctggacgc cgagcagcgc gggcggcacg ctcacccagc
    13621 ggtcggcgac cactgtggac ttcgcgtccg ggataccagg caaagcggcc cagaaagcgg
    13681 cgggcccgtt caggtaaggc gtcttgctga gcagcacgac cttggcccgc tgcccgttga
    13741 cggtgagcgt gcccagcgcc tcgccggtgc tcgccacccg caggtccacg gtcaccttgt
    13801 cgcccgacaa cgtggtgagc ccgccggtca cgtgcaacgc accggcctcg gcgaggtcgg
    13861 tcagcgactg cccggccacc tgcgcggtgg tcggcggcgg cggcgcgccg acgccggcct
    13921 gcccggcgac gctgctgtcg caggcggcga gcagcacgag cggcagcacc acaccggccc
    13981 cgcgtctgac ccgcggcctg gtcctcgacg tgacggtcag cccgacgccg agcggccacc
    14041 ggcgcgcacg ggcacgcgcc accggccctc gtcgccgaac ccgcatccgc cgctcccacc
    14101 tgaccggccc agatcacgtt tggtcgtccc cagtatggcc acccggtcgg catgcccggt
    14161 gcggttcgcc gaagcgagcc aacaatgtgg cgcagtcagt ttcccggatc ccgcaacggc
    14221 gccgatgccg acccctgcca cacaaaccct gatcgcgtgg atttccgaca ttcagccctc
    14281 attgtcgccg cggtgcgaac agccctgtgt caatgacccc tctgtcaaat ggtcctgtgt
    14341 caatggtccg ggtgcggcgg ctcagtcggc gggcaatacg gattcgttcg tcgcgctcgg
    14401 accgttggac ttgaccgacg gcgcggccgc cgccttccac ctgccggtca ccccgggaca
    14461 gccgggcgcg gtgtacctgg tgcgccacct gggcatccgg aggcgtccgg cgggtgtgcg
    14521 acgatgaccc cgccatgcca gcgttccccc tgaccagagc cgcgatcgtc gggttcggtg
    14581 gttcgctgtt gaccgccttc ggcgcggccg gggcgggtgg gacaccggtc ggcgacggcc
    14641 cgctcgtcgg caccccgttc gaggcactgc gctacggcca cggccagatg ctcgccgtcg
    14701 gctgcgtgta cgcgggcgtc ctggtcctcg ccgtcgcatg ggtgcaactg ggcatcgcgg
    14761 tgcggcacgg cgccatcgac acggccggga tgttccgcac gtcggccctc tgggcgctgc
    14821 cgctgctgac ctgcccgccg ctgttcagcc gcgacctcta cagctatgtc gcccagggag
    14881 cgctcgccgc gcacggtctc gacccgtaca ccaccggctc gtcgcggctg ccgctcgcgc
    14941 tgcacgagaa cgtgcattgg gtctggcagg acacgccgac cccgtacggt ccggtgcaca
    15001 tcatcctgac cagggcgatc gcgtcggtca ccggcgagaa cgtcgtggcc ggggtgctgc
    15061 tgacccggct cgtgttcgcc gcggggctcg tgttgctggc cgccgcgctg ccgggcatct
    15121 gccgggtcgt cggcacccgt ccggagttcg cgctctggtt cgccgtggcc aacccgctga
    15181 tgctcgtcct cgtgctcggc ggcggtcaca acgacatgct ggccatcggg ttgctcgccg
    15241 cggcgacgct gttcgtgttg cgccgcaacc acttcgccgg cctcgcgctg ctggcgctcg
    15301 cggtcgcggt caaggccacg atgctggtgg cactgccgtt cctgttgtgg tcggtgtccc
    15361 ggcgcctgca cctcgcggtc gggaaggcgc tggccgcgat ggtgccgacg ttcgtcgtgg
    15421 ccacggtgct cgcgggccac ggcttcggct gggtgcaggc gctgggctcg acgtcgctga
    15481 tcgtgaactg gatgtcgctg cccaccgggc tcggcgaggt gctcgggcag gcgctgagcc
    15541 tggactgggg cgaccgcgaa ctgctgatcg agtgcatgcg ggcggtgggg atggccaccc
    15601 tcgccgtcct cgtggtggtg ttgtggtggc gctcgcggtc cggcgcgccc gcggtcgtgc
    15661 tgcgtaacgc gacgttggcg ttgaccttgg ccgccatcct gctgccggcc accctgccct
    15721 ggtacttcag ctgggcgatc gcgctcggcg ccgtgctccc gtggtctgcg gtgtcgtgga
    15781 ccagggcccg cctggcctgc gcgagtgccg gggcggtgtg gctggtggtg tgcgactacc
    15841 cgaccggtga ggcggcggtc tacgactgga actacgtcgg catcaccctc gccatcgcgg
    15901 ccctgatcgg ggcggcggcg gtctacctgg agccggaacg ggtagaggtg gccgtgtgac
    15961 tgagttgtcc gcggcctacg cggcctgccg ggagatcaac gcggcgcacg gccgcaccta
    16021 ctacctggcg acccggttgc tgcccgcctc acgccggccg gccgtgcacg cgctctacgg
    16081 gttcgcgcgg ctggccgacg acatcgtgga cgttgtggac accccgggcg cggaccccgc
    16141 ggcccgattg gacgaactgg ccacggcggt gaaggacgcg ttcgccgggc gcccgagcac
    16201 cccggtgctg ctcgcgctgg ccgacaccgt ccgccgctac ggcatcgacc aggggctttt
    16261 cgacgacttt ctggcgtcca tgcgaatgga cctcgcggtg accggctacg ccacgatggc
    16321 cgatctgtcc gcctacatgc gggggtcggc ggcggccatc ggcctgcaga tgctgccggt
    16381 gctgggcacc gtcggtcccg aggaaccggc acgggcgccg gcgcgcgcac tcggcgaggc
    16441 gttccagctg accaatttcc tgcgggacgt cggcgaggac ctcgaccgcg gccggctgta
    16501 cctgcccgcc gacgagctgg ccgcgttcgg cgtcgaccgc gaccggctgg tgtgggcgcg
    16561 gtcgagcggc aagccagacc cgcgggtgcg ccgcgccatc gcccacctcg tcgggtacac
    16621 gcgggcggtc taccggcggg ccgagccggg gatcgcgctg ctgcgcccgg aatcacgccc
    16681 gtgtgtacgg gtggcgacga cgctctaccg cggcatcctc gacgagatcc aggacgcggg
    16741 ctacgaggtg ctcaaccgcc gggccgtggt cccgctcggg cgcaggctgc gggtcgcggg
    16801 cacaggtctg ctgcgggccc gctggcacga ccttcagaac ccgagggcct gagcgcgccg
    16861 cttgacctcc cggccgcggt tggaccgcag cgcgtcgatc ggcgtgcccg gcagcgactc
    16921 gtcgggggcg aagagccagc gcagcatctc cgtcggggtg tagccggcgt cccgcaggag
    16981 cgtcagggtc cccgagaggc ccttgaccgg ttccgagccg tcgatgagca cggcgggcat
    17041 gcacagctgg ccggcacgcc gcatggcgat caggtgtccg tcgcgaacgg actggtagat
    17101 ccggctgacg ggcaccccga gagccgttgc aacctcctcc acggggagga cgtctacctg
    17161 ggggtcgagc acgtcgtcag cggttgggat cgaactcacg ctcgacacaa tgccacaagc
    17221 cctgctcacg acaaggcgac cagatgtccg acacccgcca cgcgagcgcc gggacctccg
    17281 tacgatcgtc agttgtggag gaccggggtt ccagcctgat cggcacgctg ctggaccagc
    17341 gctaccgcat cgacgggctg ctggcgcgtg gcggcatgtc cgctgtctac cgcgcgcagg
    17401 acacccggct ggaccgtccc gtcgccgtca aggtgatgga cgagcggttc gtcgccgaca
    17461 agtcgttcgt cgaccggttc gagcaggagg cccgctcagc cgcccgcatc caccacccga
    17521 acgtggtcgc cgtgcacgac cagggcgtcg acggcgacaa gatctacctg gtgatggagc
    17581 tcgtcgacgg cgggacgctg cgcgacctgc tggaaagcgg tcccctctcg gtcgagttgg
    17641 cgtgcgcgat cctggagccg gtgctcgccg cgctgggtgc cgcgcaccgc tccgggctgg
    17701 tgcaccggga cgtgaagccg gagaacgtgc tgatcgggcg cacgtcctcg ggcgggagcg
    17761 tggtgaaggt cgccgacttc ggcctggtcc gcgcggtgtc cggctcgagc atgacgcagg
    17821 gcagcgtgat catggggacg gtcgcgtacc tctcccccga gcaggtcacc accggcaccg
    17881 cgaccgcccg cggcgacgtc tactcggcgg gcatcgtgct ctacgagatg ctcaccggcc
    17941 ggccgcccta cgtcggcgac acgacgttgt cggtggccta ccggcacgtc aacgacgacg
    18001 tccccgcccc gagcaccgtc gcgccgacca tcccggccgc ggtggacgaa ctggtcgtgc
    18061 aggccacccg tcgcgacccg gcggaccggc cgatggacgc cgacgagttc ctctcggcgt
    18121 tgcgccgggt ctgctcggcg ctggcgatcc gcccggtgcg ggtgccgatc ccggagcacg
    18181 agaacgagaa gaccatgccg gtgtccggtg cgatcgcggc cggcgcgggt tcggcgcagg
    18241 gctccgtgca gggttcgctg gacggcgcgc tcgccaccca ggtgacgggt caggccacct
    18301 ccgtcgtggc ccggccgaaa gccgtgcaca cggtcggcat cggcccgcag ggcacgcgca
    18361 cgatggcccg gtcccagttc gacgcgttga ccgagcgccg gccacccgtg cgcccgcagc
    18421 cgatgcggcc gaacccgccg aactacccac cgcccaacgg tttcccgcca cccggtgacg
    18481 actacgacga cggctacaac ggctacgacg gctatccgga gaccggggcg cagcccgagc
    18541 agcgcggccg gcgcaagggt ctgctcatca ccctcatcgt ggtcggcgcg ttgctgctcg
    18601 gtgcgggcgg cacagcgacg tggtggttca ccagcggccg ctacagcacg gtgccctcgg
    18661 tcgcgggcaa gacgcaggaa gaggcgctga aggagatctc cgacgcgcac ctgaccccga
    18721 ggctcgccga caaaccgagg ctggacaaca agatccccaa gggcatcgtg atcagcaccg
    18781 accccagcgg gggccggctg ctgcgtggca cgacggtgac gttggtcgtg tcggggggca
    18841 agcccgtcgt gccgaacatc gggcagggcg cggatcccaa ggacgccgcg aaggcgctgg
    18901 cggacgtcca gctcgtcgcg aagaaggatc cggcgaagga cgagtacaac ccgaacgtgc
    18961 cgcagggcaa ggtcatccgg gtcgacccgc ggccgggcag cgcgctggac atcggcaccg
    19021 acgtgttgct cgtgctgagc aagggccccg agcccaagcc cgtgcccgac gtggccggca
    19081 tggatcacga ccaggcgttc cagacgttgc agaccgccgg gttgaccccc gtcgacgggc
    19141 ccgcggagtt ctccgccgac gtcgacggcg gcaaggtcat ccgcaccgac ccgcccgcca
    19201 acacgatgct cgactcgtcg aacacgcaga tcacggtcat ctcgtcgaac gcggtcaccg
    19261 tcccggacct cggccagcaa ttggtcacgg acgcgcaaaa ggcgctgacc gatctcgggc
    19321 tgaccgtcca ggtggtcaac gtgtcggggc aggcggggaa cccgggcagc cgggtctacg
    19381 cccagtccgc gccgccgggc tcccgggtcc agccgggctc gcaaatcgtc ctcactgcgt
    19441 ttccataacg gatagggcga tccgaaaccc ctgagggcat cgccgcgtcc tatgctcgcc
    19501 ggacagttca cgcccggaca gttccgggcg cagcgccagg gggaggacca tgatcggcag
    19561 ccggggccgg gtgaccggca cgataggccc cggtctgatc ggtgaggtcc tgatcagtgt
    19621 tcggggcggt gtcgaggcgt tctacgccta ccccgccgac ccggacacga agatcacaat
    19681 cggtacgcag gtgctggtgg tcgacttcga cgagcccaac acggtctacg tggagccgtg
    19741 gcggccgacc aggctgaccg gctgagttcc aagcggtata cggcttttca cattcagagg
    19801 gggctcgtcg tgtcgagcac actattggtg gtcatcggcg gcgcgatcgt cgtcttgatc
    19861 gtgcttttcg cgttgctcaa agcgttctac aaagtcgctg agccgaatga ggcgctcatc
    19921 atttccggcc tcggcatcaa ccagcagcgc acgggcaccg aggacagcct gaagttcaag
    19981 atcgtgaccg ggcgcggtgt cctcgtgctg cccggtttcc agaccgcccg gcggttgtcg
    20041 ctggacaccc gcggcgccaa cctcgaggtg tcgtgtgtga ccaagcaggg gctgccggtc
    20101 accgtgcgcg cggtcgtcat ctacaaggtg ggcgacgact tctcgctgat cgccaacgcg
    20161 gcgcggcgct tcctcgacca gcaggacggc atgaacagca cgatccacga gctgttctcc
    20221 ggtcacctgc gctcgatcgt cggtggcctg accatcgagg acatgatcca caaccgcgac
    20281 gcgctgaccg gtgagatccg gcagtcgtcg gcggccgaga tgatcaagct gggcctggtc
    20341 gtcgactcgc tgcagatcca ggagattgac gacgagtcgg gctacatcct gaacctgggc
    20401 aagccgcacg cggccgcggt cgccgcctcg gcccgcatcg cggaggcgca gcgcgaccag
    20461 gaggccacgc aggccgagca gatcgcggcc gccgagaagg ccggcgcgat ccgcgagagc
    20521 cagatcaagc aggccggcta caccgccgag gtggaccagg ccaaggcgaa ggcgtcgcag
    20581 gccggcccgc tggccgaggc gaccgcgcgc caggaggtcg tcgtccagga gacccgcgcg
    20641 gccgagctgg aggccgaact ctccgagcag cgcctgcagt cgcaggtccg caagcccgcc
    20701 gacgcccgcg cgtacgagac gaggaccacg gccgacgccg agcgcgacgc gcagatcgcc
    20761 cgcgcccagg cgcaggccaa ggaaaccgag ctgcgtgcgg cggccgacgc gaccaaggtc
    20821 aagacggcgg ccgaggcgga ggcccaggcg acccgcgccc gcggtgaggc gtcggcggcg
    20881 gccacgaagg cgactggtct cgccgaggcc gactcggcca gggccaaggg tctcgcggag
    20941 gccgaagcgg cgaaggcgaa gggtctcgcc gaggccgacg cgatcaaagc ccggtcggac
    21001 gcgctggcgg agaaccagga agcggtcgtc gcgcagcagc tggcggagaa gtggccggag
    21061 atcgtggccg cgggtgcgca ggcgctgggc aacatcgacc acatggtggt gctgaacggc
    21121 gccgacggtg tgtcggacat cttcgccaag gcgctgtcgc tcggcggcac cggcctcggc
    21181 ctggcccgcc agctgatgga gggcatgaag gtcaaggaca cggacacgcc gccgaccaac
    21241 ggtgtcgtcc cgacctcgct gaccggcacg gaaaccaaga tcgactagtg ggttccggca
    21301 aaggggcgct tccgttgcgg gagcgcccct ttcgctgtca gacgagctcg gcggtgatcg
    21361 actcgtccca cccgcggtag cgcagcatgg gcgcctcgcc accttcgggg acgaactcga
    21421 tgtcgcagcc cgcggcccgg ccgatcgcgc gcaacagcac acagaattcc gcgaacgact
    21481 cctcggtcac ctcgggcagg atcggcgcga ccagcacgtc cgactccccc gggtagcact
    21541 ccagccccag gtgcggtttg gcccgcagct cgtagcggac cacaccgtcg aggtcttcgc
    21601 ggtcgacggc ccagcccgct tcggtcaccc ggtcgagcaa gccctgccac tgccgcggtc
    21661 cgaggcgcac cagcaggccg tcggcgcgcg gcagctccgc ccgcaggaag tcgccgaact
    21721 ccgcccacga cggcacatcc accgacggca ccacgatccg gtccgcgccc gcgtcgtagc
    21781 gcagcaactc ccagtccgac ccgccttcgg ggaccaaccg cacgtcgttg ccgaacgcac
    21841 ggccgaggtc ggccagcacc gcgcagagca cgtcgagccg ctcctggtca cgcacctcgc
    21901 gcaggtcgac gtcgaaggtg atgccttcgc cgtcgcggcg gaagaagttg agctccatgc
    21961 ccgggaccgg ccggacgtgg tggacctctt cgtagtgacc gggttccgcg tcccagccgc
    22021 gggtccggac caggtcgaag aaggccggcc agtcgtccgg accggtgccg gtgacgtacc
    22081 cgtccggcag cgtgccccgc tccgggtcga gcagggcagc cacccggtcg aaccgtgggc
    22141 tcaggatcgg agcatctccg cgaccaggaa cgccagttcc agcgactgct gggtgttcaa
    22201 ccgcggatcg caagcggtct cgtagcggcc gccgagctgt tcctcggaga tctcctgggc
    22261 gccgcccagg cactcggtga cgtcctcgcc ggtcagctcc acgtggatgc cgccggggtg
    22321 cgtgcccagc cggcggtgca cctcgaagaa gccctgcacc tcgtccacga tgcggtcgaa
    22381 gtgccgcgtc ttgtagccgg tggacgactc gtgggtgttg ccgtgcatcg ggtcgcactg
    22441 ccagatcacc cggtggccgg tcgactcgac cttctcgatg atcggcggca gcacgtcgcg
    22501 gaccttggtg tggcccatgc ggctgatcag cgtgagccgg ccgggggtgt cgtgcgggtc
    22561 gaggcggtgc acgtactcga cggcctgctc gggggtggtc gtcgggccga tcttgacgcc
    22621 gatcgggttc gacagcagct cggccagcgc gatgtgggcg ctgtcgagct ggcgggtgcg
    22681 ctcgccgacc cacaggaaat gcgacgacag gtcgtagagc tgcggctgac cgctctcctt
    22741 gtccaggcgc agcatcgcgc gctcgtagtc cagcagcagc gcctcgtggc tggcgaagat
    22801 ctccgtcgag tccagcgacc ggtcggtcac gccgcacgcc gacatgaagc gcaggccgcg
    22861 gtcgatctcc ttggccagcg cctcgtaacg ctcaccggcg ggcgaggtgc gcacgaagtc
    22921 cttgttccag tcgtgcaccc gggccaggct cgccatgccg gccccggtca gggcacgcag
    22981 caggttcatg gccgcgcccg cgttggcgta ggcgcggatc atccgcgacg ggtcgggcac
    23041 ccgggcctcg ggcgtcgcga ccagcgagtt cacgatgtcg ccgcggtaca cgggcaggcc
    23101 cagcgcatcg gtgccgttgg agcgcggctt ggcgtactgc ccggcgatcc ggcccacctt
    23161 gaccacgggc atgctcgcgc cgtaggtgag cacgacggcc atctgcagca acgtgcggat
    23221 gttgccgcgg atgtggggct cggtgttgtc ggcgaaggtc tcggcgcagt cgccgccctg
    23281 cagcatgaac gcctcgccgt tcgcgacgtc ggcgagccgg tcgcgcaggc ggtccacctc
    23341 cgagggcacg gtcaccggcg ggacgctctc cagcacggtg cgcacctggc ggacgtgctc
    23401 gccgtcgggc cactcgggct gctgagcagc gggccgggcg agggcgtcgt ccagctggga
    23461 acgcatgtcg ggcggcagtg gcggtagttc gggaagggtg tccaccggca catcgacggt
    23521 ccagttcaca cgtcaagact aaggagggtg gcggacgcca cgaaaaccgg gacacatctc
    23581 ccacagtccg gacgttccca cgacgctcgg cacgaggcag gatgcgaccc gtgacgagca
    23641 ccctcgaccc ggagaccgcc gcggcgttac tcgactcggc catcgccaac gtccagcgcg
    23701 attaccccgt gcactggacc catgtcatca cctcgcccga ggacctgcgg acccagcgcg
    23761 aactccaccc cgtgttcgcc ggctcgctgg actggcactc gtgcgtgcac caaacctggc
    23821 tggcggtccg cctcttacgc gttaacgctg acttacccgg cgcggcgaag gcacgcgagg
    23881 tgctcgacgg cttgctgacg ccggagaact gcgcggtgga agcggacttc ttccgcggtg
    23941 gtctcggcgc ctggtgggag cggccctacg ggtgggcgtg gctgctgacc ctggacgcgg
    24001 agctgcggac gtggtccggg ggcgcgcagt ggtcggccgc cctggcgccg ctcggcgcgg
    24061 tggtgcgcga ccggtggctg aactggatca ccggagcgcg gctgcccgtg cgcgtcggca
    24121 cgcacggcaa cacggccttc gccacgatgc tggtgctcga ggcggcgctc gccaccggcg
    24181 acgacgaact ggcttccgct tgtcgagccg cggcaacccg ctggtacctg gacgacaagg
    24241 gttacggcgg attcgagccg gacgcggcgg acttcctctc ccccgcgctg accgaggccg
    24301 atctgctgcg ccgcgtgctg cccgcttcgg acttcggcgc ctggctctcc gctttcgtgc
    24361 ccgacctggc cgaagcgcgc tgggcgcgac tgcgcgaacc ggccacagtg gacgaccccg
    24421 ccgacccgta cggcgcacac ctggccggcc tggccctgtc gcgatcgtgg gcgtggcgtg
    24481 gcatcggtga gtccctgccc gccggtcacc cgtacgcaag cctcgccgcc gccgcggccg
    24541 agacacacgc ggaattgggc tggcagtacg tgttcggcta cgggtacgag ggcgcggagc
    24601 actggctggg tacgttcgcc gcttatctgg acatcggcgc cttcaaggat cgcgtcaccc
    24661 tctagctgct gcggttcggg tagcactctg ttgggccgct attgggagct atcaggggcg
    24721 gctgccgcgg gtgttcgccg ccgggtggtt gggttggcct cggggttggg gcggcgaaca
    24781 cccttgccca cggtgccggc ggtttccgtt gcttgggtgg ccggtttgaa tggttgcgtt
    24841 gcgctgttac ctaccgtttg tcgagtggtc ccgatggtgg ctgaatggcg tgaaagaccg
    24901 gaatattcca ccattgtcgg ttaggccgtt tggtcgattg ttgtggtatg atcggggcat
    24961 ggagctgggg gagctttact cgactgtcgc gcagatgcga caactggagt tgaagctgct
    25021 cgacgacatt tcccagatcg agtggaaaga gtccgggtac ccccagttgg ggcctgtcac
    25081 gatttccgtg taagccacgg atggctaatg ttgttaacgt atcacagggg aagtcggccg
    25141 gggaatagta cgacgagtgt gttgagtgct gttttccagc cgtgggttcc ggttcctgat
    25201 tctcctcctc gtttgctgga gatgttgcgt agtccgaggt agatgagttt catggcggct
    25261 tcgtcggagg ggaagtgtcc gcgggttttg gtgattttgc ggagttggaa gttgatggat
    25321 tcgatggcgt tggtggtgta gacgatgcgg cggagttcga ctgggtagtc gaggaacggg
    25381 atgaactcgt tccaggcgcg tcgccacacg tcggtgacgc cggggtattg gcgtccccat
    25441 tcggtgtcga agtctttcaa cgcgaggtcg gcggcctcga cggtgggtgc ggtgtagatg
    25501 gcgcgcatcg acgtcgcgat cttctttcgg tcttggtagg acacgaaccg catcgcgttg
    25561 cggatcacgt gcacgacaca ggtttgcacg acggtgtccg ggaagaccgc ggtgatggcg
    25621 tcgggcagcc cggccaagcc gtcgcagcag gcgatcagga tgtcacgcag tccacggtta
    25681 cgcagctggg tgagcaccga gtgccagaac ttcgcgccct cggtttcggc gatccagcaa
    25741 cccagagcgt gcttgcggcc atccacgtcg accccgatga ccaggtgcgc gctcttgatg
    25801 gcgactgcgc ctttgtctcg gaccttggtc cggatgccgt cgacatacac gatcggatag
    25861 acctcatcga ccggccggtt acgccaaatc tcgatttcgt cggtcactac atcggtgatg
    25921 ttggagacca gctcacgaga cgctgtcacg ccgtaaacct cgaacaggtg ggcttcgata
    25981 tccctggtcg acatgccacg ggcataacag gacaggacga gctcatcgat ctgaccgacc
    26041 cgtcgtgcgc gtttcggcac gatctgtggc tcgaattcac cgttacggtc gcggggaaca
    26101 gtgatcgtca ccggcccgtt caccgtcgac accgttttcc gcgacgtgcc gttacgtgag
    26161 ttcccagtcc caacaccggc cgggtcatca cggtcgtatc cgagatgctg ggtcatctcg
    26221 gtctgcaagg ctcgttccaa gaccgccttg gtcatctggt tgagcaggcc gtcaacacca
    26281 tcgatcggcg tgccggccgc cttcgcatca gccaacaggg cgtcgatcgc cgatgggtcc
    26341 aaagccgcgc tgagccgctg agccgccgtc tcagcggcag gatcggcctg attctcgctc
    26401 acgtgggtgt ccttcccagc cgccgagttg atcagcggcc gatcttggtc cacccgcggc
    26461 ttacacagtt gtcatgacac gcccccccag ttgtggcggt tcctgcaaga cgtcctgcac
    26521 gtgaccgccc aggaggccaa gcgcctcgaa caccacgtcg agttgttgtg cccgaagatc
    26581 gggatcaccg gacagcccat cccgccccga ctgcctgccg cgcgagcagc gatggccgct
    26641 ggagagatct ccggcgcgca cgtggacaag atcgccacca cagtggagtc ggtccctgtc
    26701 gagcacgccg aacaagtcga ggcggacatg accgggctgg cgcggaagtt caaccccacc
    26761 cagctcatcc gcctgggcga gcgcatcgtc gccgccctca accccgacgg ttccaagccc
    26821 ctcgacccca ccgtggtcga tggccagaac ac
//
