LOCUS       NZ_SNXZ01000002        22247 bp    DNA     linear   CON 20-APR-2024
DEFINITION  Labedaea rhizosphaerae strain DSM 45361 Ga0310470_102, whole genome
            shotgun sequence.
ACCESSION   NZ_SNXZ01000002
VERSION     NZ_SNXZ01000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Labedaea rhizosphaerae
  ORGANISM  Labedaea rhizosphaerae
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Labedaea.
REFERENCE   1  (bases 1 to 1608339)
  AUTHORS   Goeker,M.
  TITLE     Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing
            the most valuable type-strain genomes for metagenomic binning,
            comparative biology and taxonomic classification
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1608339)
  AUTHORS   Goeker,M., Huntemann,M., Clum,A., Pillay,M., Palaniappan,K.,
            Varghese,N., Mikhailova,N., Stamatis,D., Reddy,T., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-MAR-2019) Prokaryotic Super Group, DOE Joint Genome
            Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.12.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 180.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004362825.1-RS_2024_04_19
            Annotation Date                   :: 04/19/2024 13:11:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,820
            CDSs (total)                      :: 7,753
            Genes (coding)                    :: 7,690
            CDSs (with protein)               :: 7,690
            Genes (RNA)                       :: 67
            rRNAs                             :: 3, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2 (5S)
            tRNAs                             :: 59
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 11 of 63
            Pseudo Genes (incomplete)         :: 55 of 63
            Pseudo Genes (internal stop)      :: 3 of 63
            Pseudo Genes (multiple problems)  :: 6 of 63
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 17:41:24
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1009335
            Orig. end                         :: 1031582
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            SNXZ01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22247
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="7"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22247
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22247
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12247](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12247)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    994..1007
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.47"
                     /tool="antismash"
     gene            complement(1029..2237)
                     /locus_tag="EV186_RS13895"
                     /old_locus_tag="EV186_102860"
     CDS             complement(1029..2237)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_5 (24-392). E-value: 3.7e-59.
                     Score: 192.4. Matches aSDomain:
                     nrpspksdomains_EV186_RS13895_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139: aminotransferase class V"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015100188.1"
                     /locus_tag="EV186_RS13895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_102860"
                     /product="cysteine desulfurase-like protein"
                     /protein_id="WP_133849631.1"
                     /sec_met_domain="Aminotran_5 (E-value: 1.8e-56, bitscore:
                     188.1, seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.1e-06, bitscore:
                     24.5, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 3e-07, bitscore:
                     26.5, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNEQRYDIEKIRAHFPALRAGAAHFDGPGGSQVPDVVADAVRDAM
                     VSPMANRGRVTAAERTADDITVGARQAMADLLNGEPGGVVFGRSMTQLTYDLSRALAKG
                     WGPGDEVVVSRLDHDANVRPWVQAAEAVGATVRWIDFDPETTELTTTHVAAVLSGRTRL
                     VAVTGASNLLGTRPPLAAIADLVHHAGALFFVDGVHLTAHHPVDVVACGADFFACSPYK
                     FLGPHCGVLVARPDLLETIHPDKLLPATDDVPERFELGTLPYELLAGCTATADFLSGLA
                     STAGTRRARIVESMTAVAEHEDRLREKVEAGLAELPGVTLHSKAASRTPTLLITFDGKA
                     VRDAHVFLAELNINAPAGSFYAIEPARRLGLDEGGLRIGLAPYTDDEDIDRLLAGLARF
                     TER"
     aSDomain        complement(1062..2165)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EV186_RS13895_Aminotran_5.1"
                     /evalue="3.70E-59"
                     /label="EV186_RS13895_Aminotran_5.1"
                     /locus_tag="EV186_RS13895"
                     /protein_end="392"
                     /protein_start="24"
                     /score="192.4"
                     /tool="antismash"
                     /translation="FDGPGGSQVPDVVADAVRDAMVSPMANRGRVTAAERTADDITVGA
                     RQAMADLLNGEPGGVVFGRSMTQLTYDLSRALAKGWGPGDEVVVSRLDHDANVRPWVQA
                     AEAVGATVRWIDFDPETTELTTTHVAAVLSGRTRLVAVTGASNLLGTRPPLAAIADLVH
                     HAGALFFVDGVHLTAHHPVDVVACGADFFACSPYKFLGPHCGVLVARPDLLETIHPDKL
                     LPATDDVPERFELGTLPYELLAGCTATADFLSGLASTAGTRRARIVESMTAVAEHEDRL
                     REKVEAGLAELPGVTLHSKAASRTPTLLITFDGKAVRDAHVFLAELNINAPAGSFYAIE
                     PARRLGLDEGGLRIGLAPYTDDEDIDRL"
     gene            complement(2279..2656)
                     /locus_tag="EV186_RS13900"
                     /old_locus_tag="EV186_102861"
     CDS             complement(2279..2656)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016333340.1"
                     /locus_tag="EV186_RS13900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_102861"
                     /product="VOC family protein"
                     /protein_id="WP_133849632.1"
                     /transl_table=11
                     /translation="MTDQLASVRYVVDDVQAAVDFYTGHFGFVVRTNVAPAFADVVRGP
                     LRLLLSGPASSGAKATPADAAAAGRNRIHLIVDDLDAEIDRLRAAGLGFRSDLVSGPGG
                     RQILLADPAGNLVELFQPAGS"
     gene            complement(2649..3425)
                     /locus_tag="EV186_RS13905"
                     /old_locus_tag="EV186_102862"
     CDS             complement(2649..3425)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020646787.1"
                     /locus_tag="EV186_RS13905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_102862"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_133849633.1"
                     /transl_table=11
                     /translation="MVPSSQVVPSSEAVPVFVRLAAHPVRWRLLGELAAGDHRVRELTE
                     RLGQPQNLVSYHLRLLRDGGLVTTRRSSFDARDSYYHLDLDQCAGALSTTASSLHPALR
                     PSTPAVPSGARVLFACTGNSARSPMAEALLRHRTDGRLDVTSAGSHPKPELHPTAILVL
                     RKEFGLDLAGMRPRHLDSVAGRRFDYVITLCDKVREVCPEFDDATVRSHWSIPDPATAS
                     GSDDYEAFARIAVEIDTRVRHLLPVLAANHSGGHRD"
     gene            3471..4697
                     /locus_tag="EV186_RS13910"
                     /old_locus_tag="EV186_102863"
     CDS             3471..4697
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020659014.1"
                     /locus_tag="EV186_RS13910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_102863"
                     /product="APC family permease"
                     /protein_id="WP_133849634.1"
                     /transl_table=11
                     /translation="MSGPLARRLGTGDAVVIGLGSMIGAGVFAAFGPAARAAGTGLLIG
                     LAIAAVIAYCNATASAQLAAVYPVSGGTYIYGRERLGAWWGFTAGWGFVVGKTASCAAM
                     ALTFATYAVPGPWWLQRIVAIGGVIALAALNYRGITKTATVTRVLVATSLVALAIVVVG
                     AFGRADVRNLEPVSGGVYGTLQAAGLLFFAFAGYARIATMGEEVRDPRRTIPRAIPIAL
                     FIAVAVYLVVAVAALLAAGPQGLAHASAPLTAAVPSGLAPVVRIGAALAALGALLALIA
                     GIGRTSLAMARHHDLPGWLAAVHPRHQVPHHAEIALAVVVSAIVAVVDLRGVIGFSSFG
                     VLVYYAIANAAASTQPAEQRRWPRWLNLLGVAGCVTLVVTLPWQSVVAGLVMFAIGLTG
                     RAVLARPGR"
     gene            complement(4702..5199)
                     /locus_tag="EV186_RS13915"
                     /old_locus_tag="EV186_102864"
     CDS             complement(4702..5199)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012796439.1"
                     /locus_tag="EV186_RS13915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_102864"
                     /product="general stress protein"
                     /protein_id="WP_133849635.1"
                     /transl_table=11
                     /translation="MTTAFNPGFTQYSPVTGLPTLPQGWPIGSYDTYEQAQRAVDHLAD
                     KNFPVEGVTIVGIEPMVVERVSARLTWGRVLGAGAASGAWFGLFVGLLLSFFTVGSGLY
                     AILTGLITGVVFGTAFAAMRYGATRGQRDFVSHSQLVARRYDVLTAPANAERGRDLLLQ
                     IV"
     gene            complement(5317..5982)
                     /locus_tag="EV186_RS13920"
                     /old_locus_tag="EV186_102865"
     CDS             complement(5317..5982)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EV186_RS13920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EV186_102865"
                     /product="hypothetical protein"
                     /protein_id="WP_133849636.1"
                     /transl_table=11
                     /translation="MTTEPAPAPVPTSTSTSRVPLYLAAGIGLVVGALVVGLLWLTVGG
                     SDDDAIGGGGSAPITAPAKVGEYQRFAEVPGNASGPGKATAERMSAWDSQTAQRISTAY
                     DGAAATVQTYAKADLSVIFQVQVVRANAPGLYVPYQDPKTLGLAEPQQDVKTFGAVQCI
                     VHVQARAAESESPTQVVATDCQRTGGGLTVRVPTAGGTLGEHPDQVAAVVDEVFTAIR"
     gene            complement(6007..6612)
                     /locus_tag="EV186_RS13925"
                     /old_locus_tag="EV186_102866"
     CDS             complement(6007..6612)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007034878.1"
                     /locus_tag="EV186_RS13925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_102866"
                     /product="response regulator transcription factor"
                     /protein_id="WP_133850244.1"
                     /transl_table=11
                     /translation="MIRVLLAEDQAMMRGALAVLLDLEDDIEIVGQVARGDEVVAAARA
                     AQPDVALLDIELPGASGLDAAVALRAALPRCQVIIVTTFGRPGYLRRAMEAGAKGFLVK
                     DGPVEGLAAAIRTVHGGGSVVDPALAAAALTAGPNPLTERERDVLAASGDGSTINDIAG
                     RLHLSASTVRNYLSSAIGKTGARNRMEALLQARTHGWL"
     gene            complement(6621..7736)
                     /locus_tag="EV186_RS13930"
                     /old_locus_tag="EV186_102867"
     CDS             complement(6621..7736)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF019350.4"
                     /locus_tag="EV186_RS13930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_102867"
                     /product="histidine kinase"
                     /protein_id="WP_166659165.1"
                     /transl_table=11
                     /translation="MTATVDDQCAHRAWWERSGGPFTVLFWTPLLLIAPVNDAIDARLG
                     WLAWLILAAVFALSVGAVLTATWPRVASRPASLAFVAALAAVTVTATVAYSTHWSSLYV
                     TLSVALAVTLEGWAPTAIGVAALVGAATVLGHGGTWGEAGWGCALIVFLSGMGTFAFQR
                     LFAVIAELNRTRTALAEAAVSAERVRFSRDLHDLLGHTLSVIVVKAEATRRLIPRKPDA
                     AEQHARDIEEIGRQALQDVRDAVSGYRAESLAGELDRAGKALAAAGIEVSTCDTDPALP
                     AAVDRLLGWVVREGTTNVIRHSGARECRIVLRHNGDRARLELTDDGVGGQPAGGGSGLV
                     GLRERVGAMGGSLEAGPAERGFRLSVDVPVS"
     gene            complement(7750..8325)
                     /locus_tag="EV186_RS13935"
                     /old_locus_tag="EV186_102868"
     CDS             complement(7750..8325)
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024880.4"
                     /locus_tag="EV186_RS13935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_102868"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_133849638.1"
                     /transl_table=11
                     /translation="MIPDDVDAYRVRKAALLGSLSGDVLEIGAGTGANFGYFRREVRWT
                     GLEPNRRARATLREVARAHGHDTEVLDAPAERIPLPDASVSAVVATVVLCSVTDQDATL
                     AEVIRVLRPGGRFVFFEHVAAPVGTWPRRLQRLSAPFSRVLDRGCDPARDTERAIRRAG
                     FAEVTIERYAGLRWAGVPIPLIAGTGQV"
     gene            complement(8322..8723)
                     /locus_tag="EV186_RS13940"
                     /old_locus_tag="EV186_102869"
     CDS             complement(8322..8723)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039977.3"
                     /locus_tag="EV186_RS13940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_102869"
                     /product="DUF6069 family protein"
                     /protein_id="WP_133849639.1"
                     /transl_table=11
                     /translation="MPVRWLSVAGAVAGAVLVWLIAVPVAGVDLVATPMGGSTMHVTLL
                     AVLVSSLVVGLAGLGLLTLLERRSAKGLRNWTSTAAVVLVLSLASPMGGESLGAKLSLT
                     AMHLVVGAVLIAGFRAGAARPSRVAAAAR"
     gene            8883..9494
                     /locus_tag="EV186_RS13945"
                     /old_locus_tag="EV186_102870"
     CDS             8883..9494
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EV186_RS13945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EV186_102870"
                     /product="hypothetical protein"
                     /protein_id="WP_133849640.1"
                     /transl_table=11
                     /translation="MAIVWCPLGSRTIDSVLALAEGSWARDGIDETWRAAGWLQPGRPG
                     PAKLVFDEMTYVLDAGERPATIGMEFDPDRITSIALSFATFHDATDPADPDVADLVDSV
                     YSAHWQADPGADRRRFDALWRIGYRELEARLDAPEAAGYHDEQWQYGVWRVDDTLITVY
                     QGEDFESYSTMDSASVGLLRFPRTEKVPDGKWLYELMCGV"
     gene            complement(9502..9675)
                     /locus_tag="EV186_RS38895"
                     /old_locus_tag="EV186_102871"
     CDS             complement(9502..9675)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EV186_RS38895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EV186_102871"
                     /product="hypothetical protein"
                     /protein_id="WP_166659166.1"
                     /transl_table=11
                     /translation="MGQEMVRERVRPSGFAFFGFGVEQRQPSVICGRASTWQQPRSTED
                     DDFEPNIVRGRE"
     misc_feature    complement(9792..9807)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 18.42"
                     /tool="antismash"
     gene            9831..9983
                     /locus_tag="EV186_RS38900"
                     /old_locus_tag="EV186_102872"
     CDS             9831..9983
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EV186_RS38900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EV186_102872"
                     /product="hypothetical protein"
                     /protein_id="WP_166659167.1"
                     /transl_table=11
                     /translation="MVQPVPPEPVPFPTPPPNPGPAQPSPVPPPPQPPQPPEPTPTPDP
                     MPGPQ"
     gene            complement(10001..12247)
                     /locus_tag="EV186_RS13950"
                     /old_locus_tag="EV186_102873"
     CDS             complement(10001..12247)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018684951.1"
                     /locus_tag="EV186_RS13950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_102873"
                     /product="germacradienol/geosmin synthase"
                     /protein_id="WP_133849641.1"
                     /sec_met_domain="T1TS (E-value: 2e-81, bitscore: 271.1,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQPFELPEFYMPYPARLNRNLEAARTHSKAWARGMDMLDVPQHG
                     TVIWDERDFDRHDYALLCAYTHPDCGGPELDLVTDWYVWVFYFDDHFLELFKRTRDTAG
                     ARAYLDRLPLFMPVDSTVVTEEPTNPVEAGLADLWQRTTPSMSARWRERFAESTKNLLD
                     ESLWELANINEGRVANPVEYIEMRRKVGGAPWSANLVEYAAHAEVPAEIAHSRPMHVLR
                     DTFADGVHLRNDLFSYEREVLDEGELSNGVLVFEEFLGIPTQEAADRVNDLLTSRLHQF
                     EHTALTELPPVLEEHGIGPAGRTSVLAYVKGLQDWQSGGHEWHMRSSRYMNGAAADAAA
                     TTHAGQPLGGPTGLGTAATRIVTSVLATMPQRARAFGHVPYEQVGPTPIPELRQPYKPK
                     QSPHLARSREHVVTWSRRVGILDPGSVWDERKLRAYDLPLCAAGIHPSASPDELDLSSD
                     WLAWGTYADDLYPAVFGQTRDLASAKVATERLSRLMVVDGEPAPLPLSALERGLVDLWR
                     RTTVSMAVADRRTLKQAVDTMTESWLWELANQVTNRIPDPVDYLEMRRRTFGSDLTMSL
                     RRLGHGAAIPAEVYGSRTIQALEHSAQDWACLLNDVHSYQKEIQFEGEFHNAIRVVQAF
                     FDCDRDAALGVVADLMNARMREFEHAVDVGLPALFADFGLDEQARDQLLGYAVELQDWM
                     SGIEVWHEGCHRYREADILALRDSPPGVGARVLAGPSGLGTGSVHIGQPVPATS"
     misc_feature    12436..12445
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.85"
                     /tool="antismash"
     gene            12448..12963
                     /locus_tag="EV186_RS13955"
                     /old_locus_tag="EV186_102874"
     CDS             12448..12963
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EV186_RS13955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EV186_102874"
                     /product="hypothetical protein"
                     /protein_id="WP_133849642.1"
                     /transl_table=11
                     /translation="MITDLPAGEHALWTGSPVRYPLFDRQDAVLVPFSLVWCGLVVYWT
                     ISALKASHGWFFAAWGMLLVALGLYMVVGRLIVRQVKLRKVVYTVTNLRVIIRSSARQE
                     ESRYLGQLPPPTVTESSDGSGTIRFGSTSLFHSLRSRRGTAWEDQFVLYAIPQARRVRD
                     LILTATTR"
     gene            complement(12965..13867)
                     /locus_tag="EV186_RS13960"
                     /old_locus_tag="EV186_102875"
     CDS             complement(12965..13867)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016330822.1"
                     /locus_tag="EV186_RS13960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_102875"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_133849643.1"
                     /transl_table=11
                     /translation="MSAIKTPFGFHSTASEVLDGVDLSGKRAVVTGASSGIGVETARAL
                     AAAGAEVVLAVRDLAAGERTASTIGPRASAAVLDLADLDSVRAFVRAWDGPLDILVNNA
                     GIMATPEQHTAQGWELQFAVNHLGHHALATGLHRYLAAAGAARVVSVSSSAHQGSPVIF
                     DDLHFAFRHYDPGLAYAQAKTANVLFAVGAGARWAADGITANSLMPGAIATGLQRHSGG
                     FQNPPEEAKTVEQGAATSVLLAASPLLEGIGGRYFVDCNEAEVLDRRSGDMSGVARYAI
                     DPANAERLWEVSEEMVAAG"
     misc_feature    complement(13854..13867)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.32"
                     /tool="antismash"
     gene            complement(13936..14562)
                     /locus_tag="EV186_RS13965"
                     /old_locus_tag="EV186_102876"
     CDS             complement(13936..14562)
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013222892.1"
                     /locus_tag="EV186_RS13965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_102876"
                     /product="LuxR C-terminal-related transcriptional
                     regulator"
                     /protein_id="WP_133849644.1"
                     /transl_table=11
                     /translation="MSTRIPVHVHASDAITLHGLRSQLRQEPQLAIVDREEVGPDTVAV
                     IAADAMDDDTLHELRELNRLGCRHSVLVAGTLDDAGLLAAVEVGVCALVRRQEATSSRL
                     ARLVVKAAHGEAALPSDMLARLLKQVSQLQHNVLAPRGLTIVGLTPRETSVLRLVADGL
                     DTDEIAGQLSYSPRTVKNILHGVTTRFCLRNRSHAVAYALREGLI"
     misc_feature    complement(14530..14543)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: medium, score: 18.34"
                     /tool="antismash"
     gene            complement(14652..17513)
                     /locus_tag="EV186_RS13970"
                     /old_locus_tag="EV186_102877"
     CDS             complement(14652..17513)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024589.4"
                     /locus_tag="EV186_RS13970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_102877"
                     /product="LuxR family transcriptional regulator"
                     /protein_id="WP_166659168.1"
                     /transl_table=11
                     /translation="MRIGSNETLDGHGADGFVGRTAELAKLSELAEKVRTGAPQVIWVH
                     GPAGIGKTTMVRRFLSDLTGFAVLHAAADPSESVVPYGIVDQLVRRVPQRAQVPLLASG
                     IPDEANPLAVGARLLDLLGLIQAGGSVALVVDDVQWIDAPSAHALGFVLRRVWADQVLV
                     VLLARPAEDSHSADLLGKLNHSGGGAVSLELTGLGAGEVSGLALAMTGRRLPVPAAERL
                     RDYTGGHPLHLRTLLADVPLDQLADRHSRLALPRSVVTAVRASLERLPEPSRRLLDGLA
                     VLGTRSPLARVAQVAGVREPSVALQPALDAGLVTWWPNELSSPVAIAHDLQREAIYNAL
                     PPSQRSSLHAKAAEVVDPAGAWGHRVAAATATDADLADRLEAAAEEESKAGRHDSAARY
                     LRWAADLSPERADYERRIETSCVQVLFSSDHAWALRLRPKVLQCAPSALRSLCLGLTSL
                     LALGEWGAAQRSLTTVMRLAEQDGEHVPRWVRGTAAAGLAAAYTWGGDAKRTVRVAKDA
                     LDAGDIPVLMRDYTRVLMAVARSRIDGMAAALDELDHLPRIPSAASVEHLESLACRGAI
                     RAMLGRFVEAKRDLSTVVQRHRTGTYLMSGTVPYCYLAATHYQLGEWDDASIVVRQALS
                     FEDLEEQAQNQTLRRFAATLVPAGRGDWATATEQSGLATRFAQQIGGPQDLRYAALAEA
                     ILRQAMADRRGMVAALTRVPGITEADPAEHDDAGVHEWWSLWWRPLLTEGLIGVGELDA
                     AETELTALRVSASGVRYMASTVMRLSSWHMAASGDVPGAVEAVEAFFDRPRGPSTPLAD
                     GLLEHDHGRRLLMVGRPGEAGRVLRSAKQRFARLGALPFEQRVDEDLARLEAAPEPVGV
                     PAPRRPDVLAGLTDREGEVAHLVGRSLTNREIGAELYVTTKTVEYHLGNIYAKLGITSR
                     RQLRDLLAERPHSTVPRDSPRST"
     gene            complement(17594..19714)
                     /locus_tag="EV186_RS13975"
                     /old_locus_tag="EV186_102878"
     CDS             complement(17594..19714)
                     /EC_number="3.2.1.3"
                     /GO_function="GO:0004339 - glucan 1,4-alpha-glucosidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009251 - glucan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005152912.1"
                     /locus_tag="EV186_RS13975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_102878"
                     /product="glucan 1,4-alpha-glucosidase"
                     /protein_id="WP_133849646.1"
                     /transl_table=11
                     /translation="MRRSRWLVLLACVVAILAFAMPASAQTAPGAPGIDSAWTSGAKDG
                     LGTSTTTGSKVWYTLGGGILNEVYYPQADTPDVQDLQYMVSDGSTFTDEEKVATSHEVR
                     LADSRSLTYQQVNTATNGRYRITKTYVTDPARATVLIRTRFQVLTGGPLNLYVLYNPSL
                     GNSGMGDTGATSDGKLVASDGGVADALASSIGFSAMTNGYSGTASDGFQDLTAHHALTN
                     TYDSADSAGNLVQTAQVPVGTDTTFTLALGFGGSRADAASTAGASLAQGWDAVAGSYQS
                     GWHDYLGSVNPPPASVADPALTQQYLTAVMTIKAHEDKTYRGAFVASLSVPWGNAQNGD
                     SCCVAGYHAVWARDLYQMATAEIAIGDSAAANRALDYLFTVQWRSDGSYPQNTRLDGTP
                     VFGSLQMDEVSFPIILAWQLGRTDPASYGKIKASAEFISHHGPSTPEERWEEAGGYSPS
                     TIAAEIAALVCAADLANADNDPGAADFYLRTADSWQSQVDNWVYTTSGSLAGHGYYERI
                     DDNGNPNDGHQVGIANGGGSWDERDVVDAGFLELARLGVKAPGDQHITDSVAVVDQTIR
                     VTTPEGDVWYRYNHDGYGETQAGAPFTGQGVGRLWPVLTGERGEYAVATGHQDAAQGYL
                     VTMGGSANAGGLVPEQVWDRQGANGFTFGKATGSAAPLAWAQAQFVRLAVSITAGHDIE
                     TPSVVAHRYVGG"
     gene            19841..20809
                     /locus_tag="EV186_RS13980"
                     /old_locus_tag="EV186_102879"
     CDS             19841..20809
                     /NRPS_PKS="Domain: PKS_ER (12-318). E-value: 2.6e-32.
                     Score: 104.1. Matches aSDomain:
                     nrpspksdomains_EV186_RS13980_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015098572.1"
                     /locus_tag="EV186_RS13980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV186_102879"
                     /product="zinc-binding dehydrogenase"
                     /protein_id="WP_133849647.1"
                     /sec_met_domain="ADH_N (E-value: 2.1e-07, bitscore: 27.3,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 6.8e-19, bitscore:
                     64.7, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAIRQYEFGPPQRLRYERVDDPAPGPGQVRIAVAAAGVHFIDTA
                     IRAGRRFGPPLPSLPMTPGREVAGLVESIGDGVDPAWLGVDVVAHLGMASGGYAELAVA
                     DVAALHRRSGLDPSAAVAMVGTGRTTMGLLGLAALRPDDVVLVTSAAGGIGTLLVQAAR
                     AVGATVIGVAGGAEKIRRVLLNGASIVADYTGSGWYGAVREQLYGRRVSVVFDGVGGSV
                     ATSALRLLGDGGRMLTFGWSSGASMEYDADEVAARGIKVVNALAAPMPPARELAAQALA
                     EATAGRWVPAVQAFPLASAAEAHQALEERRTSGKVVLLPAH"
     aSDomain        19877..20794
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EV186_RS13980_PKS_ER.1"
                     /evalue="2.60E-32"
                     /label="EV186_RS13980_PKS_ER.1"
                     /locus_tag="EV186_RS13980"
                     /protein_end="318"
                     /protein_start="12"
                     /score="104.1"
                     /tool="antismash"
                     /translation="QRLRYERVDDPAPGPGQVRIAVAAAGVHFIDTAIRAGRRFGPPLP
                     SLPMTPGREVAGLVESIGDGVDPAWLGVDVVAHLGMASGGYAELAVADVAALHRRSGLD
                     PSAAVAMVGTGRTTMGLLGLAALRPDDVVLVTSAAGGIGTLLVQAARAVGATVIGVAGG
                     AEKIRRVLLNGASIVADYTGSGWYGAVREQLYGRRVSVVFDGVGGSVATSALRLLGDGG
                     RMLTFGWSSGASMEYDADEVAARGIKVVNALAAPMPPARELAAQALAEATAGRWVPAVQ
                     AFPLASAAEAHQALEERRTSGKVVL"
     CDS_motif       20237..20326
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EV186_RS13980_0001"
                     /evalue="3.10E-03"
                     /label="PKSI-ER_m5"
                     /locus_tag="EV186_RS13980"
                     /protein_end="162"
                     /protein_start="132"
                     /score="10.3"
                     /tool="antismash"
                     /translation="LLGLAALRPDDVVLVTSAAGGIGTLLVQAA"
     gene            20819..21616
                     /locus_tag="EV186_RS13985"
                     /old_locus_tag="EV186_102880"
     CDS             20819..21616
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EV186_RS13985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EV186_102880"
                     /product="hypothetical protein"
                     /protein_id="WP_133849648.1"
                     /transl_table=11
                     /translation="MTYESGPWRLVRQLGAWASDTPWVRWLELGGSLGRGAGDEMSDVD
                     AGIGISLAPAEARAAALAAARGFAPVAASFVQQLDGLDHLMVQYRDGRQLSLVLDPRPD
                     RGGLPPGSKAMFDRTGELAAPGQPGPLTASADDVREWAFLAWWDLADVAKHAKRGSAWR
                     AIEALHEARTMAWRLHAAALDLDYPVFGAVTVVNAKRPAPEGLDRTLAGTPEQALPAAI
                     ALADVLDRLTDRDDPDIAGIRDHALSSFRSTATTPAGPPTPSR"
     misc_feature    complement(21901..21916)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 20.94"
                     /tool="antismash"
     misc_feature    21922..21937
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.27"
                     /tool="antismash"
ORIGIN
        1 cgccacccag gtgaacaccc ggctggccca ggaagcgacc gccgcgcagc aggagaagac
       61 cgcccgcgac gcgctcggcg ccgcgtacgc cgggtcgtgg ttcgacgcgg ccagcggtca
      121 cctggtggtc gcgagcaccg acaaggccaa ggccgccggg ctcgccgacg tcaagacggt
      181 cacggtcagg cacagcgccg ccgaactgaa cgccgtgaag agccggatcg acgcgctggc
      241 gggcaaggca gcacccgccg gggtcaccgg ctggcacgtc gacagccgca ccaacagcgt
      301 cgtggtcacg gtcaacacca aggcccggac cgcggccgtg gactcgttcg tggccaaggc
      361 gaccgcgctg ggcaacggcg tggtgcgcac cgagacggtc acggaatccc cgcgcaccaa
      421 ggccgacatc atcggcgcgc tgccgtacta catcaactac gcggcccgct gctcgatcgg
      481 cttcacggtc tacaacgggt tcgtgtcggc cgggcactgc ggcaccccgg gctcgaccgc
      541 gaccgactcg aacggcgcgc tgctcggcac gttccaggcc tcgaccttcc ccggcaacga
      601 ctggtcgtac gtcgccgccg cgggcggggt gaacctgtac ggctacatgt acggctacga
      661 cggctattac tactacgtgt ccggctcgaa cgagatgccc gagggtgcct cggtgtgccg
      721 gtccggctcc accaccggca tgcactgcgg cacgatccag gccaagaacc agaccgtgaa
      781 ctacccgcag ggcaccgtgt acgggctcac ccagaccaac gtctgcgccg agcccggcga
      841 ctccggtggt tcgtggctct cggccaacca ggcccagggc gtgacctccg gcggttcggg
      901 gaactgcacc tacggcggga cgacgttctt ccagccggtg aacccgatcc tggccaccta
      961 cgggctcacg ctggtgacca cggcgccgtg atgtcgaccc tgatcacctg agccggcgac
     1021 ggcccggttc accgctcggt gaaccgggcc aagccggcca gcaaccggtc gatgtcttcg
     1081 tcgtcggtgt agggcgcaag gccgatccgc aggccgccct catccagacc cagccggcgc
     1141 gccggttcga tggcgtagaa ggaaccggcc ggcgcgttga tgttcagctc ggccaggaac
     1201 acgtgtgcgt cgcgcaccgc cttgccgtcg aacgtgatca gcagggtggg cgtgcggctg
     1261 gcggccttcg agtgcagcgt gacgccgggc agttcggcca ggcccgcttc gaccttctcg
     1321 cgcaaccggt cctcgtgctc ggcgacggcg gtcatcgact cgacgatccg ggcccgccgg
     1381 gtgcccgcgg tcgaggcgag gccgctcagg aagtccgcgg tcgcggtgca cccggccagc
     1441 agttcgtagg gcagcgtgcc cagctcgaag cgctccggga cgtcgtcggt ggcgggcagg
     1501 agcttgtccg ggtggatggt ctcgagcagg tcgggccgcg cgaccagcac accgcagtgc
     1561 gggccgagga acttgtaggg cgagcaagcg aagaagtcgg cgccgcacgc gaccacgtcc
     1621 accgggtggt gcgcggtgag gtgcacaccg tccacgaaga acagcgcgcc ggcgtggtgg
     1681 acgaggtccg cgatcgccgc cagcggcggc cgggtgccca gcaggttgga cgcgcccgtg
     1741 accgcgacca gccgggtccg cccggacagc accgcggcga cgtgggtggt ggtcagctcg
     1801 gtggtctcgg ggtcgaagtc gatccaccgc acggtggcgc ccaccgcctc ggcggcctgc
     1861 acccacggcc ggacgttggc gtcgtggtcg agccggctga cgacgacctc gtcaccaggg
     1921 ccccaaccct tggccagcgc gcgggacagg tcgtaggtca gctgggtcat gctgcgcccg
     1981 aacacgacgc cgccgggctc gccgttgagc aggtcggcca tggcttgccg ggcaccgacg
     2041 gtgatgtcgt cggcggtgcg ctcggccgcg gtgacccgcc cccggttcgc catcggcgag
     2101 accatggcgt cgcggaccgc gtcggcgacc acgtcaggca cctgggagcc gccgggcccg
     2161 tcgaagtggg cggcaccggc acgcaaggcg gggaaatgcg cccggatctt ctcgatgtcg
     2221 taccgctgtt cgttcactgg accgacgatc gcagctgagc gtgcccgtcg gcaagcgttc
     2281 aggagccggc cggctggaac agctcgacga ggttgcccgc cgggtcggcg agcaggatct
     2341 ggcgcccgcc gggcccggac accaggtcgc tgcggaaccc gagccccgca gcacgcagcc
     2401 ggtcgatctc cgcgtcgagg tcgtcgacga tcaagtggat gcggttgcga ccggcggccg
     2461 cggcgtcggc cggagtcgcc ttggcgccgg aactggccgg gccggacagc aacaggcgaa
     2521 gcggcccgcg cacgacgtcg gcgaacgccg gcgcgacgtt ggtgcgcacg acgaaaccga
     2581 agtggccggt gtagaagtcg acggcggcct ggacgtcgtc gacgacgtag cggacgctgg
     2641 ccagctgatc agtcacggtg acctcccgag tggttggcgg cgagcaccgg aagcaggtgc
     2701 cgcaccctgg tgtcgatctc cacggcgatc cgggcgaacg cctcgtagtc gtccgacccg
     2761 ctcgccgtgg ccgggtcggg gatgctccag tggctgcgca cggtggcatc gtcgaactcc
     2821 gggcagacct cgcggacctt gtcgcacaac gtgatcacgt agtcgaaccg ccgaccggcc
     2881 accgaatcca ggtgccgtgg gcgcatcccc gcgaggtcga ggccgaactc cttgcgcagc
     2941 accagaatcg ccgtcgggtg gagttcgggc ttggggtggc tgcccgcgct cgtcacgtcg
     3001 agccgcccgt cggtgcggtg gcgcagcagg gcctcggcca tcggcgatcg cgcgctgttt
     3061 cccgtgcagg cgaacaacac ccgcgcaccg cttgggacgg cgggggtcga cggccgcaac
     3121 gccgggtgca gcgaagatgc cgtggtgctc agcgcgccag cgcactggtc gaggtccagg
     3181 tggtagtagc tgtcccgcgc gtcgaagctg ctgcgccgcg tggtgaccag cccgccgtcg
     3241 cgcagcaggc gcaagtggta ggagacaagg ttctgcggct gacccagccg ctcggtcagc
     3301 tcacgcacgc ggtgatcgcc cgccgccagc tcgcccagca accgccaccg caccgggtgc
     3361 gcggccagcc gcacgaacac cggcacagct tcgctcgacg gcacgacttg actcgacggc
     3421 accatgccga cacgatacat caaatcagtt tgatgcatta gggaggcacc gtgagcgggc
     3481 cgctcgcacg gcgactgggt accggcgacg cggtggtcat cgggctcggg tcgatgatcg
     3541 gcgcgggcgt gttcgcggcc ttcgggcccg cggcccgcgc ggcgggcacc ggcctgctga
     3601 tcggcctcgc catcgccgcc gtgatcgcct actgcaacgc caccgcctcc gcgcagctcg
     3661 cggcggtcta cccggtctcg ggcgggacct acatctacgg gcgcgagcgg ctcggcgcct
     3721 ggtggggctt caccgccggg tgggggttcg tggtcggcaa gacggcgtcg tgcgcggcga
     3781 tggcgctcac cttcgccacc tacgcggtgc ccgggccgtg gtggctgcag cggatcgtcg
     3841 ccatcggcgg cgtgatcgcc ttggccgcgc tcaactaccg cgggatcacc aagaccgcga
     3901 ccgtgacccg ggtgctggtc gccaccagcc tcgtcgcgct ggccatcgtc gtcgtcgggg
     3961 cgttcggccg tgccgacgtg cggaatctgg agccggtgag cggcggggtc tacggcaccc
     4021 tgcaggcggc cgggctgctg ttcttcgcct tcgcggggta cgcgcgcatc gcgaccatgg
     4081 gcgaagaggt gcgcgacccg cggcgcacca tcccgcgcgc catcccgatc gcgttgttca
     4141 tcgccgtcgc cgtctacctg gtcgtcgccg tggccgcgtt gctggccgcc gggccgcaag
     4201 gtcttgccca cgcgagcgcg ccgttgaccg ccgcggtccc cagcggcttg gcgcccgtgg
     4261 tgcggatcgg cgccgcgctg gccgcgctcg gggcgttgct ggcgttgatc gcgggcatcg
     4321 gccgcaccag tctggccatg gcccgccacc acgacctgcc cggctggctc gccgccgtgc
     4381 acccgcgcca ccaagtcccc caccacgccg agatcgcgct ggccgtggtg gtcagcgcga
     4441 tcgtggcggt cgtcgatctc cgtggtgtca tcgggttttc gtcgttcggg gtgctggtct
     4501 actacgccat cgccaacgcg gcggcgtcca cccagcccgc cgagcaacgg cggtggccgc
     4561 ggtggctcaa cctgctgggt gtcgcggggt gcgtgacctt ggtggtcacg ctgccgtggc
     4621 agtcggtggt ggccggtctc gtgatgttcg cgatcgggct gaccggccgg gccgtgctgg
     4681 cgcggcccgg ccggtgagcc gtcagacgat ctggagcagc aggtcccgcc cgcgctcggc
     4741 gttggccggc gcggtcagca cgtcgtagcg acgggccacg agctggctgt gcgacacgaa
     4801 gtcgcgctgg ccgcgagtgg cgccgtagcg catggccgcg aaggccgtgc cgaacacgac
     4861 accggtgatc aaaccggtca ggatcgcgta gagcccgctg cccacggtga agaagctcag
     4921 cagcagacca acgaagaggc cgaaccacgc gccggacgcc gctcccgccc cgagcacccg
     4981 gccccaggtc agccgagccg agacacgctc gaccaccatc ggctcgatcc ccacgatggt
     5041 gacgccctcg accgggaagt tcttgtcggc gaggtggtcg accgcgcgct gcgcctgctc
     5101 gtaggtgtcg taggagccga tcggccagcc ctggggcagc gtcggcaggc cggtcaccgg
     5161 cgagtactgg gtgaaaccag ggttgaatgc ggtggtcatt ggtccttcct ttcgcttgtg
     5221 cgtccacccc gtacaaccgc tgtgaagccc ggttcgtgcc ggatgccgga aacccacagg
     5281 cgactctcag cccacgctca ggtgcgcccg gcaggctcag cggatcgcgg tgaatacctc
     5341 gtccaccacg gcggcgacct gatccgggtg ctcgccgagg gtgccgcccg cggtcgggac
     5401 gcgcacggtc agcccgccac ccgtgcgctg gcagtcggtg gcgacgacct gggtcgggct
     5461 ctcgctctcg gccgcgcgcg cctggacgtg gacgatgcac tgcaccgcgc cgaacgtctt
     5521 cacgtcctgc tgcggctcgg ccaggccgag ggtcttcggg tcctggtagg gcacgtagag
     5581 gcccggcgcg ttcgcgcgga cgacctgcac ctggaagatc acgctgaggt cggccttggc
     5641 gtaggtctgg acggtggcgg cggcgccgtc gtacgcggtg gagatgcgct gcgcggtctg
     5701 gctgtcccac gccgacatcc gctcggcggt ggccttgccg gggcccgacg cgttgcccgg
     5761 cacctcggcg aaccgctggt actcgccgac cttggccggg gcggtgatcg gcgcggaacc
     5821 gccgccaccg atggcgtcgt cgtcggagcc gccgacggtc agccacagca ggccgacgac
     5881 cagggcgccg accacgaggc cgatgcctgc ggcgaggtaa aggggaacgc gggacgtgga
     5941 cgtggacgtg ggcacgggcg cgggcgcagg ttcggtggtc acccgggcat cctgcacggt
     6001 cgtggttcag agccagccgt gggtccgggc ttgcagcagg gcttccatgc ggttgcgggc
     6061 cccggtcttc ccgatggccg aggacaggta gttgcgcacg gtgctcgccg acaggtgcag
     6121 ccgcccggcg atgtcgttga tggtcgaccc gtcgccggac gcggcgagca cgtcgcgttc
     6181 ccgctcggtc aacgggttcg ggcccgcggt cagcgcggcg gcggcgagcg cggggtccac
     6241 caccgacccg ccgccatgca cggtgcggat ggccgcggcc agcccttcga ccggcccgtc
     6301 cttgaccagg aaccccttgg cccccgcttc catggcgcga cgcaggtagc cgggccggcc
     6361 gaacgtggtc acgatgatca cctggcaccg cggcagcgcg gcccgcagcg cgacggcggc
     6421 gtccaggccg ctcgccccgg gcagctcgat gtccagcaac gccacgtcgg gctgggccgc
     6481 acgggccgcc gcgacgacct cgtcgccgcg cgcgacctga cccacgatct cgatgtcgtc
     6541 ctcgaggtcg agcagcacgg cgagcgcgcc gcgcatcatg gcctggtcct cggccagcag
     6601 cacgcggatc accggactgg tcacgagacc ggcacgtcca cgctcagccg gaaaccccgc
     6661 tcggccggcc ccgcctcgag gctcccaccc atcgcgccga cgcgttcgcg cagtccgacc
     6721 aggccgctgc caccgccggc aggctggccg ccgacgccgt catcggtgag ctccagccgc
     6781 gcccggtccc cgttgtgccg caacacgatc cgacactcgc gcgcgccgga gtggcggatc
     6841 acgttggtgg tgccctcccg caccacccag cccagcaggc ggtccaccgc cgccggcagc
     6901 gcggggtcgg tgtcgcatgt ggacacctcg atgcccgccg ccgccaacgc cttgcccgcg
     6961 cggtccagtt ccccggcaag gctttccgcc cggtagccgg acacggcgtc acgcacgtcc
     7021 tgcaacgcct gccggccgat ctcctcgatg tcgcgggcgt gctgctcggc cgcgtccggc
     7081 ttgcgcggga tgagccgccg cgtcgcctcg gccttgacca cgatcaccga caacgtgtgg
     7141 ccgagcaggt cgtgcaggtc ccgcgagaac cgcacccgct cggccgacac ggcggcctcg
     7201 gcgagggccg tgcgggtccg gttcagctcg gcgatcaccg cgaacaaccg ctggaacgcg
     7261 aacgtgccca tccccgacag gaacacgatc aaggcgcacc cccagcccgc ctcgccccac
     7321 gtcccgccgt gcccgagcac ggtggcggcg ccgaccaggg cggcgacgcc gatcgccgtc
     7381 ggcgcccacc cctcgagggt caccgccaag gccaccgaca acgtcacgta gagcgacgac
     7441 cagtgggtcg agtacgccac cgtcgcggtc acggtcaccg ccgccagagc cgccacgaag
     7501 gccagcgacg ccggccgcga ggcaacccgc ggccaggtcg cggtgagcac cgcgcccacg
     7561 ctcaaggcga acaccgcggc gaggatgagc cacgcgagcc agccgagccg ggcgtcgatc
     7621 gcgtcgttga ccggggcgat cagcagcaac ggcgtccaga acagcacggt gaacgggcca
     7681 ccggaacgct cccaccacgc gcggtgcgcg cactggtcgt cgacggtcgc ggtcatgtcg
     7741 gccatcgtgc tacacctggc ccgttccggc gatcagcggg atgggcacgc ccgcccagcg
     7801 caggcccgcg taccgctcga tcgtgacctc ggcgaagccg gcgcgccgga tggcccgctc
     7861 ggtgtcccgc gccgggtcgc agccgcggtc gagcacccgg ctgaacggcg cgctcaaccg
     7921 ctgcaaccgg cggggccagg tacccaccgg cgcggcgacg tgctcgaaga acacgaaccg
     7981 gccgccgggt cgcagcaccc ggatgacctc ggcgagcgtc gcgtcctggt cggtcaccga
     8041 gcacagcacg accgtggcca cgacggcgga cacgctggcg tccggcaacg ggatccgctc
     8101 ggcgggcgcg tcgagcacct ccgtgtcgtg gccgtgggcc cgcgccacct cgcgcagcgt
     8161 ggcccgggcg cggcggttgg gctccagccc ggtccagcgc acctcacggc ggaaatagcc
     8221 gaagttggcc ccggtgcccg cgccgatctc gagcacgtcc ccgctcagcg acccgagcag
     8281 cgcggccttg cggacccggt aggcgtcgac gtcgtcgggg atcatcgggc ggccgcggcc
     8341 actcggctgg gccgggccgc gccggcccgg aagccggcga tcaacaccgc gccgacgacc
     8401 aggtgcatgg cggtgagcga cagcttcgcg cccagggact cgccgcccat cgggctggcg
     8461 agcgacagga cgagcacgac cgccgcggtg ctcgtccagt tgcgcaaacc cttggcgctg
     8521 cggcgttcca gcagggtcag cagcccgagc ccggccagcc ccaccaccag gctggagacg
     8581 agcacggcga gcagtgtgac gtgcatcgtg ctgccgccca tcggcgtggc caccaagtcg
     8641 acgcctgcca cgggcacggc gatcagccag accagcaccg ccccggccac ggcacccgcg
     8701 acactcaacc atcgaaccgg catttccttc tccccacgtc ggactggaac ttgcgatgtc
     8761 ccgaacgtag gagtcgccgc gcgcccgcgg cagagatgga tgtgtccaga tgggcaggac
     8821 aaatgtcctt ggtgtgcact gactggccca ccggtgcccg gtcggccagt acggtcctgg
     8881 ccgtggcaat cgtgtggtgt cccctgggga gcaggacgat cgactccgtg ctcgccctcg
     8941 ccgagggctc gtgggcacgc gacggcatcg acgagacctg gcgggccgcg ggctggctgc
     9001 agccgggtcg gccgggtccg gcgaagctgg tcttcgacga gatgacctac gtgctcgacg
     9061 cgggcgagcg gccggcgacc atcgggatgg agttcgaccc cgaccggatc accagcatcg
     9121 ccctgtcctt cgccacgttc cacgacgcca ccgaccccgc ggaccccgat gtggcggacc
     9181 tcgtcgattc ggtctactcc gcgcactggc aggcggatcc cggcgccgac cggcggcgct
     9241 tcgatgcctt gtggcgcatc gggtaccggg agctcgaggc gcgcctggac gcgcccgagg
     9301 cggccgggta ccacgacgag cagtggcagt acggcgtgtg gcgggtggac gacaccctga
     9361 tcaccgtcta ccagggtgag gatttcgagt cctacagcac gatggattcc gcgtcggtgg
     9421 gactgcttcg ctttccccgc accgaaaagg tgcccgacgg caagtggttg tacgaactga
     9481 tgtgcggcgt ctgagaaccg gtcactcgcg gccgcggacg atgttcggct cgaagtcgtc
     9541 gtcctcggtg ctgcgcggct gttgccacgt cgacgcgcgg ccgcagatca ccgacggctg
     9601 ccgctgctcg accccgaacc cgaaaaacgc gaagccgctg gggcggacgc gctcacgaac
     9661 catttcctga cccatgttgg ggctccttcc ggttgcctcg accattgctc gaccccaaac
     9721 caaccactac tgactatgaa actcccatca cttttcctaa acccctaggc gtttgaatag
     9781 gggtcggcca ggtaaccccg tggtgacgat ctcgagacga ggagaacgcc atggtccagc
     9841 ctgtgccgcc ggagccggtg ccgttcccga ctccgccgcc caaccccggc ccggcgcagc
     9901 cctcacccgt gccgccgccg ccgcagcccc cgcaaccgcc ggagccgacc ccgacgccgg
     9961 acccgatgcc cgggccccag taacgctcac gaggtaacgc tcacgaggtc gcaggcaccg
    10021 gttgtccgat gtggactgat ccggtgccga ggccggacgg accggcgagc acccgcgcgc
    10081 ccacgccggg tgggctgtca cgcagcgcga ggatgtccgc ttcccggtag cggtggcagc
    10141 cctcgtgcca gacctcgatg ccactcatcc agtcctgcaa ttcgaccgcg tacccgagga
    10201 gctggtcgcg tgcttgctcg tcgagtccga agtcggcgaa caacgcgggc aggccgacgt
    10261 ccacggcgtg ttcgaactcc cgcatccggg cgttcatgag gtcggcgacc acgccgagcg
    10321 cggcgtcgcg gtcgcagtcg aagaacgcct gcacgacgcg gatcgcgttg tggaactcgc
    10381 cctcgaactg gatttccttc tggtaggagt gcacgtcgtt gagcaggcac gcccagtcct
    10441 gcgcggagtg ctccagcgcc tggatcgtgc ggctgccgta gacctctgcc gggatggcgg
    10501 cgccgtgccc gagccgccgc aagctcatcg tcaggtccga gccgaacgtc cggcgccgca
    10561 tctccaggta gtccacggga tcgggaatcc ggttggtgac ctggttggcc agctcccaga
    10621 gccagctctc ggtcatggtg tccacggcct gcttgagggt ccgccggtcg gccaccgcca
    10681 tggacaccgt ggtccggcgc cacaggtcga ccagaccgcg ttccagcgct gacagcggga
    10741 gcggcgcggg ctcgccgtcg accaccatga gccgcgagag ccgctcggtg gccaccttgg
    10801 ccgaggcgag gtcacgcgtc tgcccgaaca cggccgggta gaggtcgtcg gcgtaggtgc
    10861 cccacgccag ccagtccgag gaaaggtcca gctcgtccgg gctggccgac gggtggatgc
    10921 cggccgcgca caacggcagg tcgtaggcgc gcagcttgcg ttcgtcccag acgctgcccg
    10981 ggtcgaggat gcccacccgg cgcgaccagg tgacgacgtg ctcgcgggag cgggccaggt
    11041 gcgggctctg cttcggcttg tacggctggc gcagctccgg gatcggcgtc ggaccgacct
    11101 gctcgtacgg cacgtgcccg aacgcccgcg cgcgctgcgg catggtcgcg agcaccgacg
    11161 tgacgatgcg ggtcgcggcc gtgccgagcc cggtcggccc gccgagcggc tgaccggcgt
    11221 gcgtggtcgc ggcggcgtcg gcggcagcgc cgttcatgta gcggctggag cgcatgtgcc
    11281 actcgtggcc gccggattgc cagtcctgca agcctttcac gtacgcgagc accgaagtcc
    11341 ggccggccgg accgatcccg tgctcctcca gcaccggcgg cagctcggtc agcgcggtgt
    11401 gctcgaactg gtgcagccgg gaggtgagca ggtcgttcac ccggtcggcc gcctcctggg
    11461 tggggatgcc gaggaactcc tcgaagacca gcacgccgtt ggacagctcg ccctcgtcga
    11521 gcacctcgcg ttcgtaggag aacaggtcgt tgcgcaggtg cacgccgtcg gcgaacgtgt
    11581 cgcgcaggac gtgcatcggg cgcgagtgcg cgatctcggc gggcacctcg gcgtgcgcgg
    11641 cgtactccac caggttcgcc gaccacggcg cgccacccac cttgcggcgc atctcgatgt
    11701 actccaccgg gttcgcgacg cggccctcgt tgatgttggc cagctcccac agcgactcgt
    11761 cgagcaggtt cttcgtgctc tcggcgaagc gctcgcgcca ccgcgccgac atgctcggcg
    11821 tggtccgctg ccacaggtcc gccaggccgg cctcgaccgg gttggtcggt tcctcggtca
    11881 ccaccgtgct gtcgacgggc atgaacagcg gcagccggtc gaggtaggcg cgggcgcccg
    11941 ccgtgtcacg ggtgcgcttg aacaactcca ggaagtggtc gtcgaagtag aagacccaga
    12001 cgtaccagtc ggtgaccagg tcgagttcgg ggccgccgca gtcggggtgg gtgtacgcgc
    12061 agagcagcgc gtagtcgtgc cggtcgaagt cacgctcgtc ccagatcacc gtgccgtgct
    12121 gcggcacgtc gagcatgtcc atgccccgcg cccacgcctt gctgtgcgta cgggctgcct
    12181 cgaggttgcg gttcaaccgg gccgggtagg gcatgtagaa ctcgggcaac tcgaagggct
    12241 gcgacatccg gggcgacctt tcgcgtgggg ctctcccttg gcacacaacc aagagcccgc
    12301 accgccgcca acccgtgcgg caccattcca cacgatcggg tccgccgaat ccccctggcg
    12361 gtccagcagg ccctactgag ccgagtcggc ataccgccac tcgtgcggac cgtgtaacgc
    12421 cccgcgccga attgctattt ttcgaacgtg atcaccgact tgcctgcggg cgaacacgcc
    12481 ttgtggaccg gctcgccggt tcgctacccg ttgttcgatc gccaggatgc ggtcctcgtg
    12541 ccattcagcc tcgtctggtg cggtctcgtc gtctactgga cgatctcggc gctgaaggcg
    12601 tcgcacgggt ggttcttcgc cgcctggggc atgctgctcg tggccctcgg cttgtacatg
    12661 gtcgtgggtc ggctgatcgt ccgccaggtc aagctgcgca aggtcgtgta cacggtcacg
    12721 aacctgcggg tcatcatccg ctcgagcgcg cggcaggaag aaagccgcta cctcggccag
    12781 ttgccaccgc ccaccgtcac cgagagcagt gacgggagcg ggaccatccg gttcggatcg
    12841 acgagcctgt tccacagtct ccggtcacgg cgcggcacgg cgtgggagga ccagttcgtg
    12901 ctgtacgcga tcccccaagc ccgacgggtt cgcgacctca tcctcaccgc gacgacccgc
    12961 taggtcagcc ggccgcgacc atttcctccg agacctccca gagtcgttcg gcgttcgccg
    13021 ggtcgatggc gtagcgcgcg acgccggaca tgtcacccga acggcggtcg agcacctcgg
    13081 cctcgttgca gtcgacgaag tagcggccgc cgatcccctc cagcaagggg gacgccgcga
    13141 gcagcacgga ggtggccgcg ccctgctcga cggtcttcgc ctcctcgggt gggttctgga
    13201 aaccacccga atgccgctgc agcccggtgg cgatcgcacc gggcatcagc gagttcgcgg
    13261 tgattccgtc ggcagcccag cgcgcgccgg cgccgaccgc gaagagcacg ttggccgtct
    13321 tcgcctgcgc gtacgcgagg cccgggtcgt agtggcggaa cgcgaagtgc aggtcgtcga
    13381 agatcaccgg cgagccctgg tgcgcgctgg agctcaccga cacgacgcgg gccgcgccgg
    13441 ccgcggcgag gtagcggtgc agcccggtcg ccagcgcgtg gtgcccgagg tggttgaccg
    13501 cgaactgcaa ctcccagccc tgggccgtgt gctgctcggg cgtggccatg atcccggcgt
    13561 tgttgaccag gatgtccaac gggccgtccc acgcgcggac gaacgcccgc accgagtcga
    13621 ggtcggcgag gtcgagcacc gcggccgagg cccgcggccc gatggtggat gcggtgcgct
    13681 cccccgcggc caggtcgcgc acggccagga cgacctcggc gcccgcggcc gcgagggccc
    13741 gggccgtctc gaccccgatg cccgacgacg cgccggtgac cacggcacgc ttgccgctca
    13801 ggtcgacgcc gtcgagcacc tcggacgcgg tggagtggaa accgaatggg gtcttgatcg
    13861 cgctcaccgg cccggtctag cacgaatcag cccggcttgc cgctccgatg agagcccgag
    13921 gttggggcag caccgtcaaa tgagcccctc gcgcaacgca taagcaacag catgcgaccg
    13981 gttgcgcagg cagaagcggg tcgtgacgcc gtgcaggatg ttcttgacgg tgcgcggcga
    14041 gtagctgagc tgaccggcga tctcgtcggt gtccagcccg tcggcgacca ggcgcagcac
    14101 gctggtctcc cgaggcgtga gcccgacgat ggtgagcccg cgcggggcga gcacgttgtg
    14161 ctgcaactgc gacacctgct tgagcagccg cgcgagcatg tccgagggca gggccgcttc
    14221 cccgtgcgcg gccttcacca ccagacgtgc caagcgcgac gacgtcgctt cctgcctgcg
    14281 taccagggca cacacgccga cttccacggc ggcgagcagc ccggcgtcgt ccagtgttcc
    14341 ggcgaccagc accgagtgcc ggcagccgag gcggttcagc tcgcgcagtt cgtgcagcgt
    14401 gtcgtcatcc atggcgtcgg cggcgatgac cgcgacggtg tccggcccca cctcctcccg
    14461 gtcgacgatc gcgagctgcg gctcctggcg cagctgggat cgcagaccgt gcaaggtgat
    14521 cgcgtcggat gcatgcacgt gcacggggat gcgtgtgctc atcggtcctc cctcatggcg
    14581 gagtgagtaa ggggtcgagc aaccgcacaa actctccttg agagcaggtc cgagcgccct
    14641 ggggaatgcc cctaggtgct gcgggggctg tccctaggga cagtcgagtg aggtctttcg
    14701 gccaacaggt cgcgcagttg gcgcctggag gtgatgccga gcttcgcgta gatgttgccc
    14761 aggtggtatt ccacggtctt cgtggtcacg tacagctcgg cgccgatctc ccggttggtc
    14821 aggctgcggc cgacgaggtg ggcaacttcc ccttcccggt cggtcagccc cgcgagcacg
    14881 tccgggcgtc gcggcgcggg cacgccgacc ggttccgggg cggcctccag gcgcgccagg
    14941 tcctcgtcca cgcgttgctc gaacgggagc gcgccgagcc gggcgaagcg ctgcttggcc
    15001 gagcgcagca cgcggcccgc ctcgcccggc cggcccacca tcagcagccg gcggccgtgg
    15061 tcgtgttcca gcaacccgtc ggcgagcggg gtgctcggcc cgcgcggacg gtcgaagaac
    15121 gcctcgacgg cctcgaccgc gcccggcacg tcgccgctcg ccgccatgtg ccacgagctc
    15181 aggcgcatca ccgtgctcgc catgtaacgc accccggatg cgctgacgcg cagcgcggtc
    15241 agctcggtct cggccgcgtc gagctcgccc acgccgatca gcccctcggt gagcagcggg
    15301 cgccaccaga ggctccacca ctcgtgcacg cccgcgtcgt cgtgctcggc cgggtcggcc
    15361 tcggtgatgc ccggtacccg ggtcagggcg gccaccatgc cgcggcgatc ggccatggcc
    15421 tggcgcagga tcgcctcggc cagcgcggcg tagcgcaggt cctgcgggcc gccgatctgc
    15481 tgggcgaacc gggtggcgag gccggactgc tccgtcgcgg tcgcccagtc gccgcgcccg
    15541 gcgggcacca gggtcgcggc gaagcggcgc agggtctggt tctgcgcctg ttcctccagg
    15601 tcctcgaagg acagggcctg gcggaccaca atggacgcgt cgtcccactc ccccagctgg
    15661 tagtgcgtcg cggcgaggta gcagtacggc accgtgccgg acatcaggta ggtgcccgtg
    15721 cggtggcgct gcaccacagt ggacaggtcg cgtttggcct cgacgaaccg gccgagcatg
    15781 gcgcggatcg cgccgcggca ggcgaggctt tccaggtgct cgaccgacgc ggcgctcggg
    15841 atgcggggca ggtggtcgag ctcgtccagg gccgccgcca tgccgtcgat ccggctgcgg
    15901 gccacggcca tgagcacgcg cgtgtagtcg cgcatcagca cggggatgtc gcccgcgtcc
    15961 agcgcgtcct tggccacgcg cacggtgcgc ttcgcgtcgc cgccccaggt gtaggcggcg
    16021 gcgagcccgg cggccgcggt gccccggacc cagcgcggca cgtgctcgcc gtcttgttcg
    16081 gccagccgca tgaccgtggt gagcgagcgc tgcgccgcgc cccactcgcc gagcgcgagc
    16141 agcgaggtga ggcccaggca cagcgaacgc agggccgacg gggcgcactg caacaccttc
    16201 ggccgcaacc gcaacgccca cgcgtgatca ctgctgaaca acacctgtac gcaggaggtc
    16261 tcgatgcgcc gttcgtagtc ggcccgctcc ggggacagat ccgcggccca gcgcaggtag
    16321 cgggcggccg agtcgtggcg gccggccttc gactcctcct cggctgcggc ctcgagccgg
    16381 tcggcgaggt cggcgtcggt cgcggtggcc gccgcgaccc ggtgccccca cgcgccggcc
    16441 gggtccacga cctcggccgc cttggcgtgc aggctgctgc gctgcgaagg cggcaacgcg
    16501 ttgtagatcg cctcgcgctg caggtcgtgc gcgatcgcga ccgggctgga gagctcgttg
    16561 ggccaccacg tgaccaggcc cgcgtccagc gcgggctgca gcgccacgct cggctcacgc
    16621 accccggcca cctgggcgac ccgggccagc gggctgcggg tgccgagcac cgccagcccg
    16681 tcgagcagcc gccggctcgg ctccggcagg cgctcgagcg acgcccgcac ggccgtcacc
    16741 accgaccggg gcagcgcgag gcggctgtgc cggtcggcga gctggtcgag cgggacgtcg
    16801 gcgagcagcg tgcgcaggtg cagcgggtgc ccgccggtgt agtcgcgcag ccgctctgcg
    16861 gccgggaccg gcaggcggcg cccggtcatc gccaacgcca ggccgctgac ctcgcccgcg
    16921 ccgagtccgg tcagctcgag cgacaccgcg ccgccgccgg agtggttcag cttgccgagc
    16981 aggtccgcgg agtgggagtc ctcggccggg cgggcgagca gcaccacgag cacctggtcg
    17041 gcccagaccc ggcgcaacac gaaacccagc gcgtgcgccg agggcgcgtc gatccactgg
    17101 acgtcgtcga cgaccagcgc gaccgagccg ccggcctgga tgaggccgag caggtcgagc
    17161 agccgcgcac cgaccgcgag cgggttcgcc tcgtcgggga tgcccgacgc gagcagcggc
    17221 acctgggcgc gctggggcac ccgtcgcacc aactggtcga cgatcccgta cggcaccacc
    17281 gactcgctgg ggtcggcggc cgcgtgcagc accgcgaagc ccgtcaggtc ggacaggaac
    17341 cggcgcacca tcgtcgtctt gccgatgcct gccgggccgt gcacccagat cacctggggc
    17401 gcgcccgtgc gcaccttctc ggccaactcg gacagcttgg ccagttctgc tgtacgaccg
    17461 acgaacccgt cggctccgtg tccgtcaagt gtctcgttcg aaccgattct caccgcgcgt
    17521 cggccccctc ggtcctgccc cgacccgaag ggacaaacgc ttgagccacc gcgagagtta
    17581 cgcccgaatc gtctcaaccg cccacatagc ggtgcgcgac cactgagggt gtctcgatgt
    17641 cgtgaccggc ggtgatcgag acagccagac ggacgaactg cgcctgggcc caggcaaggg
    17701 gcgcggccga ccccgtcgcc ttgccgaagg tgaagccgtt ggccccttgc cggtcccaaa
    17761 cctgttctgg cacaaggcca ccggcgttcg ccgagccccc catcgtcact aggtaaccct
    17821 gcgcggcgtc ttggtggccg gtggcgacgg cgtactcgcc gcgctcgccg gtgagcaccg
    17881 gccacagcct tcccacgccc tgcccggtga acggtgcgcc cgcctgcgtc tcgccgtagc
    17941 cgtcgtggtt gtagcggtac cagacgtcgc cttccggggt ggtcacgcgg atggtctggt
    18001 cgaccaccgc gaccgaatcg gtgatgtgct ggtcacccgg cgctttcacg ccgagccttg
    18061 ccagctcgag gaagcccgcg tcgaccacgt cgcgctcgtc ccagctgccg ccaccgttgg
    18121 cgatgcccac ctggtggccg tcgttggggt tgccgttgtc gtcgatgcgt tcgtagtacc
    18181 cgtgtccggc aagggatccc gacgtcgtgt acacccaatt gtccacctgg gactgccagg
    18241 agtcggcggt ccgcaggtag aagtcggcgg cgccggggtc gttgtcggcg ttcgccaggt
    18301 cggcggcgca gaccagcgcg gcgatctcgg cggcgatggt cgacggcgag tagccgcccg
    18361 cttcctccca gcgctcctcc ggggtggacg ggccgtggtg ggagatgaac tcggccgagg
    18421 ccttgatctt gccgtagctc gccgggtcgg tgcggcccag ctgccaggcc aggatgatcg
    18481 ggaacgacac ctcgtccatt tgcaggctgc cgaacaccgg cgtgccgtcg agccgggtgt
    18541 tctgcgggta ggaaccgtcc gaacgccact ggacggtgaa caggtagtcc agcgcgcggt
    18601 tcgcggcggc gctgtcgccg atggcgatct cggccgtcgc catctggtaa agatcacgcg
    18661 cccacaccgc gtggtacccg gccacgcaac aggaatcgcc gttctgggcg ttgccccacg
    18721 gcacggagag cgacgcgacg aacgcgccgc ggtaggtctt gtcctcgtgc gccttgatcg
    18781 tcatcacggc ggtcaggtac tgctgggtca gcgccgggtc ggccacgctg gccggcggcg
    18841 ggttcaccga gcccaggtag tcgtgccagc ccgattggta cgacccggcg accgcgtccc
    18901 agccctgggc cagcgacgcg ccggcggtgc tcgcggcgtc ggcccggctg ccgccgaagc
    18961 cgagcgcgag ggtgaacgtc gtgtcggtgc ccaccgggac ctgggcggtc tgcacgaggt
    19021 tgcccgcgga gtccgcgctg tcgtaggtgt tcgtgagcgc gtggtgcgcg gtcaggtcct
    19081 ggaacccgtc gctcgcggtg cccgagtagc cgttggtcat cgccgagaag ccgatggagc
    19141 tggccaacgc gtcggccacg ccgccgtcgc tggcgaccag cttgccgtcg gacgtggcac
    19201 cggtgtcgcc catcccgctg ttgcccaacg aggggttgta gagcacgtag aggttcaacg
    19261 ggccgccggt gagcacctgg aaccgggtcc ggatcagcac ggtggcccgc gccggatcgg
    19321 tgacgtaggt cttggtgatc ctgtagcggc cgttggtcgc ggtgttcacc tgctggtagg
    19381 tcagcgagcg gctgtcggcc aggcgcacct cgtgggaggt cgcgaccttc tcctcgtcgg
    19441 tgaacgtgct gccgtcgctg accatgtact gcaggtcctg cacgtccggc gtgtcggcct
    19501 gcgggtagta gacctcgttg aggatgccgc cgccgagggt gtaccagacc ttcgagccgg
    19561 tggtggtcga cgtgccgagg ccgtccttgg cgccggacgt ccacgccgag tcgatgcctg
    19621 gggcaccggg cgcggtctgc gcgctggccg gcatcgcgaa cgcgaggatc gccaccacgc
    19681 acgcgagcag gaccagccac cgtgaacgcc gcatgggtcc aaccctggtg agccgcgtcc
    19741 gaccctgtca acggtttgcc gacaagtcca gacgaagtgt ggggagtttt ccccacacac
    19801 gtcttgacct ccagttagct cgaagtcgga tcgttgggcc atgcgggcga tcaggcagta
    19861 cgagttcggg ccgccgcagc ggctgcgcta cgagcgggtc gacgacccgg caccggggcc
    19921 ggggcaggtg cggatcgcgg tggccgcggc cggggtgcac ttcatcgaca cggcgatccg
    19981 ggccggccgg cggttcgggc cgccgctgcc gtcgctgccg atgacaccgg ggcgcgaggt
    20041 cgccggcttg gtcgagtcca ttggcgacgg cgtggatccc gcctggctgg gcgtggacgt
    20101 ggtggcgcac ttgggcatgg cgagcggggg ctacgccgag cttgcggtcg ccgacgtggc
    20161 ggcgctgcac cggcgctccg gcctggaccc gtcggccgcg gtcgccatgg tcggcaccgg
    20221 gcgcaccacc atgggcctgc tcgggctggc cgccctgcga ccggacgacg tcgtgttggt
    20281 gacctccgcg gcgggcggga tcgggacgtt gctcgtgcag gccgcgcggg ccgtcggggc
    20341 gacggtgatc ggcgtggccg gtggcgcgga gaagatccgc cgggtgctgc tgaacggggc
    20401 gtcgatcgtg gccgactaca ccgggagcgg gtggtacggc gcggtgcgcg agcagttgta
    20461 cgggcggcgg gtgagcgtgg tgttcgacgg cgtcggcggc tccgtggcga cctcggcgct
    20521 gcgcctgctc ggcgacggcg ggcggatgct gaccttcggc tggtccagcg gcgcgagcat
    20581 ggagtacgac gcggacgagg tggcggcgcg ggggatcaag gtggtgaacg cgctcgccgc
    20641 tccgatgccg ccggcgcggg aactggccgc ccaggccctg gccgaggcga ccgccggccg
    20701 gtgggtgccc gcggtgcagg ccttcccgct cgcttcggcg gccgaggcgc accaggccct
    20761 ggaggagcgg cggaccagcg ggaaggtcgt gctgctgccc gctcactagg gtggagccat
    20821 gacgtacgag tccgggccgt ggcggctggt ccgccagttg ggtgcgtggg cgtcggacac
    20881 gccgtgggtc cggtggctgg agctcggcgg ctcgctgggc cggggcgcgg gcgacgagat
    20941 gtccgatgtg gacgcgggca tcgggatctc gctggcgccc gccgaggcgc gtgctgcggc
    21001 gctggccgcg gcacgcgggt tcgcgcccgt ggcggcttcg ttcgtgcaac agctcgacgg
    21061 cctcgaccac ctcatggtgc agtaccgcga cggccgtcag ctcagcctcg tgctcgaccc
    21121 gcggcccgac cgcggcggcc tgccgcccgg ctcgaaggcg atgttcgacc gcaccggcga
    21181 gctcgccgcg ccggggcagc caggccccct caccgcgtcg gcggacgacg tgcgggagtg
    21241 ggcgttcctg gcgtggtggg acctggccga cgtcgccaag cacgccaagc gcggctcggc
    21301 ctggcgcgcg atcgaggccc tgcacgaggc acgcacgatg gcgtggcgcc tgcacgcggc
    21361 ggcactcgac ctcgactacc cggtgttcgg cgcggtcacg gtggtcaacg ccaagcgccc
    21421 cgcgcccgag ggcctcgacc ggaccttggc gggcacgccg gagcaggcgc tcccggccgc
    21481 gatcgcgctg gccgacgtgc tcgaccggct gaccgatcgc gacgacccgg acatcgcggg
    21541 catccgcgac cacgcactca gctcttttcg ttccacggca accactccgg caggtccgcc
    21601 gacaccgtct cggtgaacac cggcgggcgc cgctgcaaga acgagacgac gccctcgacc
    21661 gcgtcacggc tcgtcgtgca gccggcgatc agccgcgagt cgacctcgtg cgccaccgcg
    21721 gggctgtcga aggcgctcag ccggaagagc atctgccgga tcaccgcgac cgggaccggc
    21781 gccgtggtcg cgaccagctc cgccgccagc gcgtaggccg cgtccagcac ggccgccggc
    21841 tcgtgcaggc tgtgcaccag cccggcgtcc agcgcctcgg cggcgtcgaa cacccggccg
    21901 ctgaccatcc agtccatcgc gacgccgagg ccgaccagcc gcggcaggaa ccacgtcgag
    21961 ccgccctccg ggtacaaccc gcgcctgctg aagacgaacc cgaagcgcga gtccgtcgcg
    22021 gccaggcggt agtcggcggg caggacgatc gtcgagccgg cgccgaccgc agcgccgcgc
    22081 agggccgcga tcaccggctt ggcgcaggtg tagatcgcct tcaccactcg gcccgcaggt
    22141 tcctgccagc cgggctcgga cgccgacgcg ttgagcgggc cgccggacag gtccgcgccc
    22201 acgcagaagt cggcgccccg gccggtcagc acgatcacgc gcacgtc
//
