LOCUS       NZ_SLWR01000008        29760 bp    DNA     linear   CON 05-APR-2024
DEFINITION  Kribbella antiqua strain VKM Ac-2541 Ga0310564_108, whole genome
            shotgun sequence.
ACCESSION   NZ_SLWR01000008
VERSION     NZ_SLWR01000008.1
KEYWORDS    WGS; RefSeq.
SOURCE      Kribbella antiqua
  ORGANISM  Kribbella antiqua
            Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
            Kribbellaceae; Kribbella.
REFERENCE   1  (bases 1 to 441048)
  AUTHORS   Whitman,W.B., Woyke,T., Klenk,H.P., Zhou,Y., Lilburn,T.G.,
            Beck,B.J., De Vos,P., Vandamme,P., Eisen,J.A., Garrity,G.,
            Hugenholtz,P. and Kyrpides,N.C.
  TITLE     Genomic Encyclopedia of Bacterial and Archaeal Type Strains, Phase
            III: the genomes of soil and plant-associated and newly described
            type strains
  JOURNAL   Stand Genomic Sci 10, 26 (2015)
   PUBMED   26203337
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 441048)
  AUTHORS   Whitman,W., Huntemann,M., Clum,A., Pillay,M., Palaniappan,K.,
            Varghese,N., Mikhailova,N., Stamatis,D., Reddy,T., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Prokaryotic Super Group, DOE Joint Genome
            Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.12.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 185.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004345665.1-RS_2024_04_05
            Annotation Date                   :: 04/05/2024 04:15:41
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,825
            CDSs (total)                      :: 7,760
            Genes (coding)                    :: 7,713
            CDSs (with protein)               :: 7,713
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 58
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 7 of 47
            Pseudo Genes (incomplete)         :: 41 of 47
            Pseudo Genes (internal stop)      :: 3 of 47
            Pseudo Genes (multiple problems)  :: 4 of 47
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:43:35
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 78446
            Orig. end                         :: 108206
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            SLWR01000008.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..29760
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NI-siderophore"
                     /region_number="1"
                     /rules="IucA_IucC"
                     /tool="antismash"
     cand_cluster    1..29760
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="IucA_IucC"
                     /kind="single"
                     /product="NI-siderophore"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..29760
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[14000:15760](-)"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(14001..15760)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
     gene            complement(419..1198)
                     /locus_tag="EV646_RS22695"
                     /old_locus_tag="EV646_10883"
     CDS             complement(419..1198)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR03083.1"
                     /locus_tag="EV646_RS22695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_10883"
                     /product="maleylpyruvate isomerase family
                     mycothiol-dependent enzyme"
                     /protein_id="WP_132151752.1"
                     /transl_table=11
                     /translation="MFAVLAGEIGRADRQRSKVHRDSEIQAWHDLLASLEGTEWHRRTV
                     CDAWDVADIAGHLIGQAEDVIKPWSFPRRFRKGKRVYPGVPRFDAHMMVQADEHRGTPP
                     AELRALFDRTWGKATRAIARNPELIRRVTMNVEGLPMALGYVWDILLARDLWMHRDDVC
                     QALGRPFDAGPYAEEVIAQVVYDVDTLPFWGERPAIVLELTGQGGGIYRLGRDEPVGRA
                     AVDAVSYMRTLSGRDDSPVVSGDPVAVEAVATCRMPF"
     gene            complement(1201..1839)
                     /locus_tag="EV646_RS22700"
                     /old_locus_tag="EV646_10884"
     CDS             complement(1201..1839)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012655.4"
                     /locus_tag="EV646_RS22700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_10884"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_158291001.1"
                     /transl_table=11
                     /translation="MSSTAGLDRRTRRRQETIEEILEVAIELMETEGVAALSLSAVARR
                     LGMQPPSLYQYFPSKMAIYDALFQRGNELVRDAYRSAYAEAGTDDQLELNLIAATAFCR
                     WCLEHQVYAQLLFWRTIPGFVPSPEAFAPAQESIQDLRDWLQATIDAGLLHPDAAGDEG
                     IALYTSMTAGLLSQQLANEPDASFEDGRFIRLLPVVLEMFYQRYAPTRG"
     misc_feature    complement(1875..1891)
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 21.26"
                     /tool="antismash"
     gene            1928..2194
                     /locus_tag="EV646_RS22705"
                     /old_locus_tag="EV646_10885"
     CDS             1928..2194
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012922919.1"
                     /locus_tag="EV646_RS22705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_10885"
                     /product="DUF2277 domain-containing protein"
                     /protein_id="WP_132151756.1"
                     /transl_table=11
                     /translation="MCRNITVLRGLEPAATSEEIYAAALQYVRKVTGVGSLSSTTRGPI
                     ERAAAEVAKITEQLLAEMPERKVPPQTVPPLRRPEVRARLGLD"
     gene            2204..2560
                     /locus_tag="EV646_RS22710"
                     /old_locus_tag="EV646_10886"
     CDS             2204..2560
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EV646_RS22710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EV646_10886"
                     /product="hypothetical protein"
                     /protein_id="WP_132151758.1"
                     /transl_table=11
                     /translation="MGQEAGTSRRRQGLVLGLIVVGVLLSLTNTNAQSELVRRREDTCD
                     GSLPLPTGAYVLGFTGLAVGSVALVLLVRWFGGSREPIALILFATAIAAVVVEIFAVVT
                     AFQEGQPVYPMCGG"
     gene            complement(2557..3576)
                     /locus_tag="EV646_RS22715"
                     /old_locus_tag="EV646_10887"
     CDS             complement(2557..3576)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EV646_RS22715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EV646_10887"
                     /product="hypothetical protein"
                     /protein_id="WP_132151760.1"
                     /transl_table=11
                     /translation="MPVELPKELVEDPFWVRLPPPIRSMIVFALLFGFTALLGIAASKG
                     GKESDAFVEGVPWTIWRTIAGAALAVFVVLTVQALRILQRPNEWGIFRAPGRRRRYLLL
                     AAIGAGAVVWFRVRHPVGGLELPVQGLGWRTRTVLIAGMVASVPWLTIVWLAHAECHDL
                     EKEIPRGTNGHLENNYMAAMQDEPGESEHLRSAVERLEQLWQLLLFSVGAFTFGVVAAV
                     ASSGALRGAFVAAYPERADEFPPANVLMYGLLFALGLSIIAVPMAVQWRNRAQQLVEHA
                     CPLPPDGKPTAEWVESRQRIEQLLHLDISILRNPLTILSVFAPLLISALAAFLPQVAG"
     misc_feature    3789..3800
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.07"
                     /tool="antismash"
     gene            3814..4653
                     /locus_tag="EV646_RS22720"
                     /old_locus_tag="EV646_10888"
     CDS             3814..4653
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070967 - coenzyme F420 binding [Evidence
                     IEA]"
                     /GO_process="GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012922918.1"
                     /locus_tag="EV646_RS22720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_10888"
                     /product="TIGR03560 family F420-dependent LLM class
                     oxidoreductase"
                     /protein_id="WP_132151762.1"
                     /transl_table=11
                     /translation="MRFAIKTRPEHTTWQQLRDVWIAADDFEIFESAWHWDHFYPLSGD
                     MAGPNLEAWTTLAALAQATQRIRVGCQVTGMIYRHPAVLANMAATTDIISNGRLELGVG
                     AGWNEMETAAYGIELYPLKERFDRFDEGVQAMIALLTEKVANFDGKYIKLTDAYCEPKA
                     VQTPHPPITIGGKGPKRTLRAVAKWAQHWNVIVPSPEEWKPLKDVLVKHCEDIGRDVNE
                     ITCSVNVRIDADQPLDAAVASAAAYGEAGVDLVVMNLPLDAAPSVVEPLAKALAPLA"
     gene            4664..4969
                     /locus_tag="EV646_RS22725"
                     /old_locus_tag="EV646_10889"
     CDS             4664..4969
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011754943.1"
                     /locus_tag="EV646_RS22725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_10889"
                     /product="MGMT family protein"
                     /protein_id="WP_132151764.1"
                     /transl_table=11
                     /translation="MDREEYVEAVLQAVESIPPGSVATYGDIAEYVGQGGPRQVGAVMR
                     EYGGGVAWWRVIRASGVPADEVGDEQLHLLRADGVRITNGRVNLRQVRWDPEIQEH"
     gene            4997..5512
                     /locus_tag="EV646_RS22730"
                     /old_locus_tag="EV646_10890"
     CDS             4997..5512
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012792.4"
                     /locus_tag="EV646_RS22730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_10890"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_132151766.1"
                     /transl_table=11
                     /translation="MNTWSVKPASVDSAEALALLRDFYITVADRWSTLYLGRPNTPEEI
                     ETGLAEYPSTHLAPPTGLFLIGRYGGAVAGCVGLKIKDADTVELSRVFVRPAYHGTGGG
                     AALLAAIESAARELGASRIVLDTRLDLSEARALYLKHGYQEIPPYKEEKYAEVFYAKEL
                     AGPPGHHN"
     gene            5692..8874
                     /locus_tag="EV646_RS22735"
                     /old_locus_tag="EV646_10891"
     CDS             5692..8874
                     /EC_number="3.6.4.-"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004386 - helicase activity [Evidence
                     IEA]"
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020385759.1"
                     /locus_tag="EV646_RS22735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_10891"
                     /product="ATP-dependent DNA helicase"
                     /protein_id="WP_277875128.1"
                     /transl_table=11
                     /translation="MRAEGRSADAPVLDADQQAVVDHPGGPLLVLAGPGTGKTTTLVEA
                     VVDRVRNRGLSPDEVLVLTFGRKAATELRDRITGRLGRTTRVMPSMTFHSFCYALLRRF
                     TPADAFDVPLRLPSGPEQSLRLSEALSGSREVGAVHWPRSLHPALKTRGFTDEVQAVIG
                     KARQLGLDPEDLSAIGRSAERAEWVAVGDFFEEYLQILDHEQVLDYSELIHRAVILAQQ
                     PQVQAKLRTEFKAVFVDEYQDTDPGQTQLLQAIAGDGRDLVVVGDPDQSIYTFRGADVR
                     GLLRFTEEFRTADGAEAAQIALGTTRRFGTTISRVSRNVVSRLGVPGTLDRDTFERFRN
                     PDASGCVYGHGKVEANVYSTSGAELEHIADLLRRAHVQDGVGWNEMAVLVRSGSRSIPP
                     LRRALAAAGIPVDVAGDELPLSREPAVRPMLLALRAVADPSTLTVDVVRALALSPLGAM
                     DAGQLRRLARVLRRRDREAAGGQRLPRSSDELLREALLNPLLLDAEASSAEARFAALGE
                     RLLKARNIVTAGAAPDEVMWSLWSDSPWLRRLRAQANSGGETARTANRDLDSLCALFDA
                     ASRAEEQVGFKGVSAFLSELESLDIAADHRFDATYREAGVQLMTAHRSKGLQWRLVVVA
                     SVQEGQWPDLRRRGSLLEPDRLGPDGLVEPLSAGALLAEERRLFYVAITRARERLIVTA
                     VQAPEADGDQPSRLLAELDIPVKLVAGRPRRPLSLHGLVADLRCVLADPASSPALKRVA
                     ADRLAVLADAADDRGQPLVPTADPARWWGVRERTRSAVPIANPELPVPLSGSALTTIVD
                     CPLKWFLTRRAGGETPSTSAIGFGQVLHTLADAVASGALPPDADELNGWLDKVWTQLEF
                     ESAWISDRERVEAEQALRRFVAWHQGRPDRELIGTEVEFDVLLPDADKPAVRVKGRMDR
                     IEADSEGTIRVVDLKTGRSMPTKPALERHVQLAIYQRAIASRQLPVVGQDPVAGGAELV
                     QLRHDDSGFPKVQHQGPLESDDDGRTWLDEAVDDAEAMVRSEEFVAKRNDGCTRCEARP
                     LCPIQPEGREIL"
     gene            8874..12098
                     /locus_tag="EV646_RS22740"
                     /old_locus_tag="EV646_10892"
     CDS             8874..12098
                     /EC_number="3.6.4.-"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004386 - helicase activity [Evidence
                     IEA]"
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020385760.1"
                     /locus_tag="EV646_RS22740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_10892"
                     /product="ATP-dependent DNA helicase"
                     /protein_id="WP_132151770.1"
                     /transl_table=11
                     /translation="MRAHLTTTAELCDLLGIPFSDQQLAAITAPLAPGVIVAGAGSGKT
                     TAMAARVVWLICTGQVKPEEVLGLTFTKKAANELDVRIREDLTKAGVLGSTLPKDQHPI
                     LAAHLRSNIPNWEQEEPGEPVVSTYHAFAGTLIAEHGLRLGLEPDARVLADATRFQLAG
                     RVVRRSSGPIRFASHHVPTLVNSLLSLDGELADHLLTADAVREHDEGVRREVAAAAKQT
                     VEVRKLAETALKRGEILQLVEEYQAYKAERGVVDFADQMALGARLAEECPEVAVVERSR
                     YKVVLLDEYQDTSVSQRRMLTALFAGPGGQGHPVTAVGDPCQAIYGWRGASVANLDEFP
                     EHFPNADGTPAQRYVLSINRRCGSRILAAANQHATELYEQHPGVIPLEAPPDAPEGAIT
                     VGLFETRSQEIEWVADAIVAAHKTPNRRWKDIGILMRTNVDLSAVHEALIARKVPVEVV
                     GLGGLLALPEVVDVVATLQAVNDLTANAAMLRILTGPRYRIGHRDLALLANRSRILADA
                     GDRPAADDLVAALDAAVAGMDSTEVISLAEAVDDPGSLEYSPDALVRFKELSAELRELR
                     AHAAEPLLDLVRRVISTIGLDVELTATPEHVDSARRDHLAAFLDAVGNFVSTESDGSLD
                     GLLAYLAAEEEYAAGLDLAVPSEADSVKLLTTHRSKGLEWPIVFVPTLVSKVFPSDRGR
                     DKWTTNAKVLPWPLRGDADTLPDFHDLSNAGLKAFADECKDVNALEERRLGYVAFTRAK
                     EILVATGHWWGPTQKRPRGPSSYLSLLKQHAGERVISWAPQPELSEENPELAEQTQAPW
                     PTPYDAASYERRLEAAALVSLARAEGPSLEAEESLLLDEQATVARWDSEIERLLSEARE
                     SRSRKAYDVALPAALSATQVMRLAKDPDGLASELARPMPRKPNRAARFGTRFHAWVESY
                     FGQQLLLDPDDLPGAADEGIVDDTDLTELMDAFRTGPYGETTPYEIEAPFALAIGGRVI
                     RGRIDAVYQVVRPDGSRGYDVIDWKTSRSETADPLQLAIYRLAWSELHNIPLHNVTAAF
                     YYVRTADIIRPANLPGRQELITLLNG"
     gene            complement(12088..12621)
                     /locus_tag="EV646_RS22745"
                     /old_locus_tag="EV646_10893"
     CDS             complement(12088..12621)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020391236.1"
                     /locus_tag="EV646_RS22745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_10893"
                     /product="Uma2 family endonuclease"
                     /protein_id="WP_241996261.1"
                     /transl_table=11
                     /translation="MRPIEPDEFTTADLEVTPDDGMRYELVDGVLIITSTPPTIHQRAL
                     GELCFLLAPVCPEDLEVLHGVEFRPHSRLALVPDLVVFRCDDIGVQWLEGPLLLAVEIL
                     SPATRTVDQVFKRKLYETAGVASYWMFDPDEVRLTALELEEGRYVERAVVSEDEVFEAE
                     IPFPVKVVPAELIR"
     misc_feature    complement(12598..12611)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.96"
                     /tool="antismash"
     misc_feature    12632..12645
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 18.86"
                     /tool="antismash"
     gene            complement(12693..13235)
                     /locus_tag="EV646_RS22750"
                     /old_locus_tag="EV646_10894"
     CDS             complement(12693..13235)
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020391236.1"
                     /locus_tag="EV646_RS22750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_10894"
                     /product="Uma2 family endonuclease"
                     /protein_id="WP_132151772.1"
                     /transl_table=11
                     /translation="MEPIASGPYTLAYLETAPDDGRRREIIDGGLCVTPSPSRIHQRAV
                     IRLGGKLNLSCPAGLEVLVAPFDYQPTSERSLQPDVLVCNPEDRGSDKLRKPLLLAVEI
                     LSPSTKMLDLLLKRGVYEQAGVRSYWILDPDKEALTVLELVDGAYVERDVVTGEKAFDA
                     ELPFPVRIVPAELLREC"
     misc_feature    complement(12954..12956)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(13348..13860)
                     /locus_tag="EV646_RS22755"
     CDS             complement(13348..13860)
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012922914.1"
                     /locus_tag="EV646_RS22755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Uma2 family endonuclease"
                     /protein_id="WP_132151774.1"
                     /transl_table=11
                     /translation="MTSEQVVEVPRDGRRYEVVDGRLLITGAQPPAHHAAVVALMVVLK
                     QACPPDLLVSVGSLDFRPAVDISLRPDLLVCRREDAGRQLLQHPPLLAVEVLSPTTRTT
                     DVVLKRTLYETHHVPSYWLLDPTHHELTILELTETGYTCRAALQSEETFHATHPFPVTL
                     TPADLTR"
     gene            complement(14001..15248)
                     /locus_tag="EV646_RS22760"
                     /old_locus_tag="EV646_10896"
     CDS             complement(14001..15248)
                     /GO_process="GO:0019290 - siderophore biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016099.4"
                     /locus_tag="EV646_RS22760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_10896"
                     /product="IucA/IucC family protein"
                     /protein_id="WP_277875129.1"
                     /sec_met_domain="IucA_IucC (E-value: 2.3e-60, bitscore:
                     198.9, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLTWIAVRRDRTTISHSTTITYDELLQTELGYDALRRFAQRIVA
                     VGADPADYVYLPVHPWQWEHKTSITFAADIAQRHIIQLGSSDDEYQPQQSIRTFFNRSE
                     PSRHYVKTALSVLNMGFMRGLSPTYMAATPAINDWVYRLVENDLVLKRYGFSVLREIAA
                     AGYHNRYYESATEKTSPYRKMLSALWRESPVPALEPGERLATMASLLHVDRHGASLAAA
                     LIRASGLAPADWFRAYIDVYLIPLLHSFYAYELVFMPHGENLILVLRNSVPTRVIMKDI
                     AEEIAVLSPATPLPPDAERVRAEVPDDEKLLSIFTDVFDCIFRFLSPLLDREGLLAPAE
                     FWSVVASAVRDYQAATPELASAFAKYDIFAPSFALSCLNRLQLKNNQQMVDLTDVAGSL
                     QFVGTLDNPLVTEAAG"
     gene            complement(15239..15760)
                     /locus_tag="EV646_RS40670"
                     /old_locus_tag="EV646_10897"
     CDS             complement(15239..15760)
                     /GO_process="GO:0019290 - siderophore biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016099.4"
                     /locus_tag="EV646_RS40670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_10897"
                     /product="IucA/IucC family protein"
                     /protein_id="WP_277875130.1"
                     /sec_met_domain="IucA_IucC (E-value: 5e-12, bitscore: 40.5,
                     seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTEHLNPDTWAVANRALVRKALAEFIHERILEPVATGNGYQLSG
                     GTSQYTFTAKLYPLNHWEVDAASIERFVDGQAAPVDALDFITEFHQQLGIGAEMLPVYL
                     EEISSTLASASYKLSKPDLTASDLVAADFQTIEAAMTEGHPCFVANNGRLGFGATDYRA
                     FAPETGKPCG"
     gene            complement(15764..16342)
                     /locus_tag="EV646_RS22765"
                     /old_locus_tag="EV646_10898"
     CDS             complement(15764..16342)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1203: putative siderophore biosynthesis protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012922911.1"
                     /locus_tag="EV646_RS22765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_10898"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_132151776.1"
                     /transl_table=11
                     /translation="MTRALSHRRFFAGIGTLSLRPFDLTEDVTTLHGWVSQPYARYWGL
                     LNASVDDVHAEYLRIAQSGHHRAFLGEHDGRPAFLMERYEPSYDAVGKLYDVAPGDIGM
                     HVLVAPPDQRIPGFTGAVFETILDCLFRDPLIDRIVVEPDVRNTKIHALNERMGFRKHS
                     IVDLPNKQAWLSLCTRDQYAEATRMNEAG"
     misc_feature    16373..16391
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 26.4"
                     /tool="antismash"
     gene            16459..16698
                     /locus_tag="EV646_RS22770"
                     /old_locus_tag="EV646_10899"
     CDS             16459..16698
                     /GO_function="GO:0070273 - phosphatidylinositol-4-phosphate
                     binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017530.4"
                     /locus_tag="EV646_RS22770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_10899"
                     /product="GPP34 family phosphoprotein"
                     /protein_id="WP_241996262.1"
                     /transl_table=11
                     /translation="MGRQPDERTGALIALLSALNVVPKVVTDAVDKRALRKRAKEIAAS
                     DWAADAVKKAVAEMQAAVTTAVVVSASAAASSGS"
     gene            complement(16684..18219)
                     /locus_tag="EV646_RS22775"
                     /old_locus_tag="EV646_108100"
     CDS             complement(16684..18219)
                     /NRPS_PKS="Domain: AMP-binding (10-409). E-value: 9.9e-88.
                     Score: 286.4. Matches aSDomain:
                     nrpspksdomains_EV646_RS22775_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017935596.1"
                     /locus_tag="EV646_RS22775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_108100"
                     /product="long-chain fatty acid--CoA ligase"
                     /protein_id="WP_132151780.1"
                     /sec_met_domain="AMP-binding (E-value: 8.5e-99, bitscore:
                     325.6, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLVDYLDKGASLDPGAACLTTDGETLTYAEVQQLSGRIAAGLAA
                     SGVRPGGKVAILAANDPIAFSCVFGISRAGAIWCPINPRNEAAENRELLDQFDCEVLIY
                     QAAFAPLVDRIRDALPKVHTFVCLDDPDGWDAFCGSASQPAPDLTDPDDLAMIVGTGGT
                     TGRPKGVMLSNTNLETMTALTLMSYPFGDRPVYLALAPLTHAAGVLCFPILAFGGEVVI
                     MRTPDVHLFLSLIPTCRVTHTFLPPTLIYMVLGAPELDATDLSSLRCFWYGAAPMSVSR
                     LEEALHRIGPVMAQLFGQTEAPMMISVLPPSDHFDASGNIAVGRLSSAGRPSPLVTTAI
                     MGADGSLLGRGERGEIVVRGSLVMKGYYRNPEATAAASAYGWHHTGDIGYLDDENYLYI
                     VDRAKDMIITGGFNVYSTEVEQALMAHAAVQDCAVIGQPDEKWGERVVAVVQPQPGTTV
                     DPVELISFVKARIGSVKAPKEVLLWPDLPRSKVGKVLKPDIKARLSAAESAAG"
     aSDomain        complement(16993..18189)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EV646_RS22775_AMP-binding.1"
                     /evalue="9.90E-88"
                     /label="EV646_RS22775_AMP-binding.1"
                     /locus_tag="EV646_RS22775"
                     /protein_end="409"
                     /protein_start="10"
                     /score="286.4"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="ASLDPGAACLTTDGETLTYAEVQQLSGRIAAGLAASGVRPGGKVA
                     ILAANDPIAFSCVFGISRAGAIWCPINPRNEAAENRELLDQFDCEVLIYQAAFAPLVDR
                     IRDALPKVHTFVCLDDPDGWDAFCGSASQPAPDLTDPDDLAMIVGTGGTTGRPKGVMLS
                     NTNLETMTALTLMSYPFGDRPVYLALAPLTHAAGVLCFPILAFGGEVVIMRTPDVHLFL
                     SLIPTCRVTHTFLPPTLIYMVLGAPELDATDLSSLRCFWYGAAPMSVSRLEEALHRIGP
                     VMAQLFGQTEAPMMISVLPPSDHFDASGNIAVGRLSSAGRPSPLVTTAIMGADGSLLGR
                     GERGEIVVRGSLVMKGYYRNPEATAAASAYGWHHTGDIGYLDDENYLYIVDRAKDMIIT
                     "
     CDS_motif       complement(17089..17169)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EV646_RS22775_0002"
                     /evalue="1.50E-07"
                     /label="NRPS-A_a6"
                     /locus_tag="EV646_RS22775"
                     /protein_end="377"
                     /protein_start="350"
                     /score="23.7"
                     /tool="antismash"
                     /translation="GERGEIVVRGSLVMKGYYRNPEATAAA"
     CDS_motif       complement(17701..17757)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EV646_RS22775_0001"
                     /evalue="1.60E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="EV646_RS22775"
                     /protein_end="173"
                     /protein_start="154"
                     /score="17.6"
                     /tool="antismash"
                     /translation="AMIVGTGGTTGRPKGVMLS"
     gene            complement(18229..19353)
                     /locus_tag="EV646_RS22780"
                     /old_locus_tag="EV646_108101"
     CDS             complement(18229..19353)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020389135.1"
                     /locus_tag="EV646_RS22780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_108101"
                     /product="DUF5938 domain-containing protein"
                     /protein_id="WP_199237130.1"
                     /transl_table=11
                     /translation="MTSKPVVVYGASGYTGRLVCEYLRQYHVPFVAAGRSEDKLKESMD
                     SHVAGIETADYEVAGVEHDVDALTDLFKGASVVLNTVGPFSELGPAAVEAALAAGAHYT
                     DTTGEQDWLITCDEKYGADFAAAGLLLAPGIAQMYTTGEIAAQLCLEQPGLDTLDIAVF
                     WGGSPTIASTRTILVNAATSKAHYLEQNAYVEFPEQGLVPLVVPGQHELALSLPWGGTS
                     HPVWFKRDPRVANCKAQGGVFNAALMNGVPQIVAAALEATKDMAPDDRNAALTETARQV
                     MNQMPPRENPRVNKSLDSVHASGPLGRAHCVIHGNSNYQQTGLLQAYAAYSLLQTPPKR
                     VGFASGCQAFGHRELLGVLRSFGLVSEPQLTVLH"
     gene            complement(19353..20159)
                     /locus_tag="EV646_RS22785"
                     /old_locus_tag="EV646_108102"
     CDS             complement(19353..20159)
                     /NRPS_PKS="Domain: PKS_KR (11-175). E-value: 3.1e-09.
                     Score: 28.9. Matches aSDomain:
                     nrpspksdomains_EV646_RS22785_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020389134.1"
                     /locus_tag="EV646_RS22785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_108102"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_132151784.1"
                     /sec_met_domain="adh_short (E-value: 6.7e-31, bitscore:
                     102.4, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 7.6e-31, bitscore:
                     102.6, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGGIDLTGRKALVTGGAQGLGEGMAKALAAAGAKVVISDLQKDLG
                     EAVADALDSEYGAGNGFVAHDITDEGSWENAVVAASDILGGLDILVNNAGVEITSLLTE
                     VTSDDIRKMLDVNVLGTTLGLKWGLRTMRPGGLAGQGGAIVNVASVAATIAFPGIAVYS
                     ATKSAVDRLTRVAAMESGKLGYGVRVNCIYPGLVPTAMGAGLANDVARLGLFESPEAAV
                     AAVVGLTPAGRLGEVTDMADAVVFLASDEARFITGIGLPVDGGMGM"
     aSDomain        complement(19635..20126)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EV646_RS22785_PKS_KR.1"
                     /evalue="3.10E-09"
                     /label="EV646_RS22785_PKS_KR.1"
                     /locus_tag="EV646_RS22785"
                     /protein_end="175"
                     /protein_start="11"
                     /score="28.9"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="LVTGGAQGLGEGMAKALAAAGAKVVISDLQKDLGEAVADALDSEY
                     GAGNGFVAHDITDEGSWENAVVAASDILGGLDILVNNAGVEITSLLTEVTSDDIRKMLD
                     VNVLGTTLGLKWGLRTMRPGGLAGQGGAIVNVASVAATIAFPGIAVYSATKSAVDRLTR
                     V"
     CDS_motif       complement(20052..20126)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EV646_RS22785_0001"
                     /evalue="5.70E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="EV646_RS22785"
                     /protein_end="36"
                     /protein_start="11"
                     /score="15.8"
                     /tool="antismash"
                     /translation="LVTGGAQGLGEGMAKALAAAGAKVV"
     misc_feature    20232..20247
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.85"
                     /tool="antismash"
     gene            20328..20966
                     /locus_tag="EV646_RS22790"
                     /old_locus_tag="EV646_108103"
     CDS             20328..20966
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020389133.1"
                     /locus_tag="EV646_RS22790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_108103"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_241996263.1"
                     /transl_table=11
                     /translation="MSSASAAEPSRPARVSGIDKIERRRVALAESALKTLGELGYARTS
                     LREIANNSEFTHGVVHYYFRDKVDLISYCVRYYKTKCAQRYDEVVETAGSAEELAAGFL
                     SKMAQTLVEETPMHRLWYDLRAQSMFEEQLRPDVAAIDQLLEEMIWRILTRYADLSGTE
                     PAVDAPTAYALVDGLFEQAVVNYAADPAGARDLLTGRVEQVLPKLVYSA"
     gene            complement(20954..21361)
                     /locus_tag="EV646_RS22795"
                     /old_locus_tag="EV646_108104"
     CDS             complement(20954..21361)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020391231.1"
                     /locus_tag="EV646_RS22795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_108104"
                     /product="hypothetical protein"
                     /protein_id="WP_241996264.1"
                     /transl_table=11
                     /translation="MLPTINAAQVVTGLTNAGYKCSTDVTYATCTAGAASVWVLTGNHP
                     RPPVVSLHSAGPAEKASAAIAKVLPQALEIAHINERQQITDWFGKQKSTASAQLTAGDW
                     LVDYIVEVDTDEPGVHLTLTDKLCKTNCQAE"
     gene            complement(21505..22218)
                     /gene="deoD"
                     /locus_tag="EV646_RS22800"
                     /old_locus_tag="EV646_108105"
     CDS             complement(21505..22218)
                     /EC_number="2.4.2.1"
                     /GO_function="GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0043096 - purine nucleobase salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="deoD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020391230.1"
                     /locus_tag="EV646_RS22800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_108105"
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="WP_132151788.1"
                     /transl_table=11
                     /translation="MSIHIAAEKGQIAPRVLFPGDPLRAKWIAETYLDDVICYTEIRNM
                     FGFTGTYKGERISVQGSGMGQPSASIYAHELFTEYDVQTLIRVGTCGALTESVRVRDVI
                     VAMSASTDSQMNRLRFHGIEYAPTADYQLLRSTVDAAEAAGLNVHVGQVFSGDLFYNDR
                     PDLVSRTAEYGVLGVEMEAAALYTLAAKFGRRALGIMTVSDHLITHEVTSAEERQTTFS
                     EMITIALDAAIEVPV"
     misc_feature    22208..22221
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.94"
                     /tool="antismash"
     gene            22282..23205
                     /gene="nudC"
                     /locus_tag="EV646_RS22805"
                     /old_locus_tag="EV646_108106"
     CDS             22282..23205
                     /EC_number="3.6.1.22"
                     /GO_function="GO:0000210 - NAD+ diphosphatase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="nudC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012922906.1"
                     /locus_tag="EV646_RS22805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_108106"
                     /product="NAD(+) diphosphatase"
                     /protein_id="WP_241996265.1"
                     /transl_table=11
                     /translation="MAYSIASGSLALSRSVLDRAADRRRDEEWLEKAWHAPDTQVAVVA
                     QDKLVVTADRTALKLVPSSEAPEGTRVFLGIDRESGAGQTAEGRAVFAVLVDGEPDESY
                     AGLREIGAVLNDREAGIAVHVVGLSNWHGVHTHCANCGEHTEVVEAGHVRDCPACGAKH
                     FPRSDPAIIVLVTDDQDRALLGRNEAWPEGRYSTLAGFVEPGESLEAAVRREVLEETGV
                     IVGPEIEYAGSQPWPLPSSLMLGFYAKAVGFEIEVDADEIAEARWFTREDLRALVEAGT
                     MALPGNISISRRLIEGWYGEELTGSW"
     gene            complement(23270..23509)
                     /locus_tag="EV646_RS22810"
                     /old_locus_tag="EV646_108107"
     CDS             complement(23270..23509)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020391228.1"
                     /locus_tag="EV646_RS22810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_108107"
                     /product="mycoredoxin"
                     /protein_id="WP_132151792.1"
                     /transl_table=11
                     /translation="MAAFTMYSTPWCGYCHRLKGQLKRAGIEFTEVDIEQVPDAAALVE
                     KINNGNQTVPTVVFPDGTAMTNPSLAQVAEKLAA"
     misc_feature    complement(23469..23486)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.59"
                     /tool="antismash"
     gene            23609..25720
                     /locus_tag="EV646_RS22815"
                     /old_locus_tag="EV646_108108"
     CDS             23609..25720
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020391227.1"
                     /locus_tag="EV646_RS22815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_108108"
                     /product="ATP-dependent DNA helicase UvrD2"
                     /protein_id="WP_132151794.1"
                     /transl_table=11
                     /translation="MSPSVSDLTRSASADSLLEALDPEQRAVATTLHGPVVVMAGAGTG
                     KTRAITHRIAYGVRTGTFDPLRVLAVTFTQRAAGEMRGRLAQLGVEGVQARTFHSAALR
                     QAKWFWPKVYGGELPPIADRKFPLLTEAASRCRVRVDTPALRDLAGEVEWAKVSNVRPD
                     DYARLAPRSGRTLAAFDPATIARIFAAYEDVKLERGRIDLEDVLLCAVALLAEDERVAA
                     EIRRQYRTFVVDEYQDVSPLQQSLLDLWLGGREDVCVVGDPAQTIYSWAGADPENLVRF
                     ASRHPSASVIKLVRDYRSTPQIVDVANKILDAAGPSGLPGRVTLRSQREAGPAPTYREY
                     SDEVAEADAVARAISRLRDDGTALRDIAVLFRTNAQSENFEQALAERKIPTVLKGAERF
                     FERAEIRQAAVLLRGQAKAGDVSDDLVSTVTGVLGGAGWTPEPPTGTGAVRDRWESLSA
                     LVTMTSDFAAAHPSAGLVDLMAELDRRASIQHAPLAEGVTLATLHAAKGLEWDCVFIVG
                     AHEGTLPISYAQTPAQVEEERRLFYVGVTRAKEQLFVSWSMSRSPGGRGTRGPTRFLDP
                     IGVRTSRTSSTEWERPPAEARAPRSGKPIPKCRVCGRGLLDPGARKLGRCEDCPSSIDQ
                     DLYDALIAWRTEQASAERMPAFVILTDATLTAIAETRPTDEQALRRIPGIGHAKLTKYG
                     ELILNLCTR"
     misc_feature    complement(23620..23635)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.39"
                     /tool="antismash"
     gene            26078..26275
                     /locus_tag="EV646_RS22820"
                     /old_locus_tag="EV646_108109"
     CDS             26078..26275
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020391226.1"
                     /locus_tag="EV646_RS22820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_108109"
                     /product="hypothetical protein"
                     /protein_id="WP_132151796.1"
                     /transl_table=11
                     /translation="MNINTVKKPFSDVVALPCAPIQGASPRLHVATVVLMASGAAQFKG
                     GAVGDVKYGGSGSRAWSPPV"
     misc_feature    complement(26093..26108)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.55"
                     /tool="antismash"
     gene            26422..26709
                     /locus_tag="EV646_RS22825"
                     /old_locus_tag="EV646_108110"
     CDS             26422..26709
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012922902.1"
                     /locus_tag="EV646_RS22825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_108110"
                     /product="WhiB family transcriptional regulator"
                     /protein_id="WP_132151798.1"
                     /transl_table=11
                     /translation="MSVSFLDVFTEVASSQDLPCRSYAPELFFAESPADVEYAKSLCTT
                     CPLKAECLAGALERSEPWGVWGGELFVQGVVVPRKRPRGRPRKSDTVTAA"
     misc_feature    26767..26782
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.94"
                     /tool="antismash"
     gene            26773..26958
                     /locus_tag="EV646_RS22830"
                     /old_locus_tag="EV646_108111"
     CDS             26773..26958
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020391225.1"
                     /locus_tag="EV646_RS22830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_108111"
                     /product="hypothetical protein"
                     /protein_id="WP_132151800.1"
                     /transl_table=11
                     /translation="MHLLHEDLARAHCRAKLHDAEQNRRFRLAQQIERAQKQAERAGRR
                     AERASARARLALARLV"
     misc_feature    26779..26781
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(27067..27594)
                     /locus_tag="EV646_RS22835"
                     /old_locus_tag="EV646_108112"
     CDS             complement(27067..27594)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020391224.1"
                     /locus_tag="EV646_RS22835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_108112"
                     /product="NUDIX domain-containing protein"
                     /protein_id="WP_132151802.1"
                     /transl_table=11
                     /translation="MRWHIHGEEEAWSSPWLSVRRLDVEQPDGERVDYHAIRLSDVAAA
                     VVMVDSSVLLMWRHRFLTDTWGWELPMGIVEPGEAPVAAAAREVEEETGWRPGPLTELI
                     RSQPGAGIMDSTHHVFRTTSASYVGPPVERNESDRIEWIPLPDIPGMITRHEILSGITL
                     LGLQQTLLAQTI"
     gene            27647..28441
                     /locus_tag="EV646_RS22840"
                     /old_locus_tag="EV646_108113"
     CDS             27647..28441
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (22-129). E-value:
                     3.5e-21. Score: 67.8. Matches aSDomain:
                     nrpspksdomains_EV646_RS22840_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024109.4"
                     /locus_tag="EV646_RS22840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_108113"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_199237131.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 5.9e-23, bitscore:
                     77.4, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 5e-18, bitscore: 60.4,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELVDVGGRRIAYHRAGAGEPAVLLHGGWSDGRAWQRQLAGLAGF
                     DLIAWDAPGCGGSADPAARMTLSDYADVLAEVVTALGVERAHLCGLSWGGGLAIAVWQR
                     HPELVRSLVLAGAYAGWKGSLPPDEVEARVRRIRAEAERPPAEWMDGYLPSFFAGPVPA
                     EATQLIRTMMAESRPAGSLMMLTAFAEADLSAVLPTIDVPTLLLWGECDQRAPVGTVAA
                     TLWARIPGAELVVLPGVGHYNNLEAPEEFNAEVRRFLGDSRR"
     aSDomain        27713..28033
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EV646_RS22840_Abhydrolase_1.1"
                     /evalue="3.50E-21"
                     /label="EV646_RS22840_Abhydrolase_1.1"
                     /locus_tag="EV646_RS22840"
                     /protein_end="129"
                     /protein_start="22"
                     /score="67.8"
                     /tool="antismash"
                     /translation="VLLHGGWSDGRAWQRQLAGLAGFDLIAWDAPGCGGSADPAARMTL
                     SDYADVLAEVVTALGVERAHLCGLSWGGGLAIAVWQRHPELVRSLVLAGAYAGWKGSLP
                     PDE"
     gene            28479..28652
                     /locus_tag="EV646_RS38930"
                     /old_locus_tag="EV646_108114"
     CDS             28479..28652
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020391223.1"
                     /locus_tag="EV646_RS38930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_108114"
                     /product="hypothetical protein"
                     /protein_id="WP_158291002.1"
                     /transl_table=11
                     /translation="MRMVRATCGLCGQQAETEEAPLTWVTSVENGRKLLYCDRCARENV
                     RNIEGKLDSVYW"
     misc_feature    28959..28974
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.9"
                     /tool="antismash"
ORIGIN
        1 gcggccgacg cggccgtcgg ctcgaccatc tcggtgaagc agctgagcga gtggatcaag
       61 ctgaaggaca acggcgagaa ggacttcgtc ctgatcgacg tccgcgagcc gaacgagtac
      121 gaaatcaaca agatcccggg ctcggtgctg atcccgaagg ccgacttcca gaccggtgtg
      181 gcgctggaga agctgccgca ggacaagcag ctggtcttcc actgcaagtc cggcgtccgc
      241 tccgccgagg tgctcgccat cgccaagggc gccggcttct ccgacgccgt ccacgtaggt
      301 ggcggggttg tcgcctgggt cgaccagatc gacccaagcc agccgtcgta ctaacagccg
      361 tcgtaccaac agacagttgc tgagggctgg agcgcaatgc tccagccctc aggcatgtct
      421 agaagggcat ccggcaggtg gcgactgctt ctacggcgac tggatcgccg gagacgacgg
      481 gtgagtcgtc gcggccggac agggttcgca tgtagctcac ggcgtccacc gcggcacgtc
      541 cgaccggctc gtccctcccg agtcggtaga tcccgccgcc ctgtccggtg agctccagta
      601 cgatggccgg ccgctcaccc cagaacggca gcgtgtccac gtcgtacacg acctgcgcga
      661 tgacctcctc ggcgtacggc ccggcgtcga acggccgccc gagtgcctgg cacacgtcgt
      721 cgcgatgcat ccacagatcc cgggccagca ggatgtccca gacatagccg agggccatcg
      781 ggagtccctc gacgttcatg gtcacccgcc ggatcagctc gggattccgc gcgatcgccc
      841 gcgtcgcctt cccccaggtc cggtcgaaca acgcccgcag ttcggccggc ggcgtaccgc
      901 ggtgttcgtc ggcctggacc atcatgtgcg cgtcgaaccg gggcacgccg gggtagaccc
      961 gcttgccctt gcggaaccgg cgcgggaacg accacggctt gatcacgtcc tcggcctggc
     1021 cgatcagatg cccggcgatg tccgcgacat cccacgcgtc gcagaccgta cggcggtgcc
     1081 actcggtccc ctcgagtgac gccagcaagt cgtgccacgc ctggatctcg gagtcccggt
     1141 ggaccttgga ccgttgccga tcagcccggc cgatctcccc cgcgagtact gcaaacatca
     1201 ctaccccctg gttggtgcgt atcgctgata gaacatctcg agtacgacgg gcagcagccg
     1261 aatgaaccgc ccgtcctcga acgacgcatc cggctcattc gccagctgct gcgagagcag
     1321 gccggctgtc atcgacgtgt agagcgcgat gccctcgtcg ccggccgcgt ccgggtggag
     1381 caggccggcg tcgatcgtcg cctgtagcca gtcacgcagg tcctggatcg attcctgtgc
     1441 cggggcgaac gcctccgggc tcggcacgaa gccgggaatc gtccgccaga acaacagctg
     1501 ggcgtacacc tggtgctcca ggcaccagcg gcagaacgcg gtggccgcga tcaggttgag
     1561 ctcgagctga tcgtcggtgc ccgcctccgc gtacgccgac cggtacgcgt cccgcaccag
     1621 ctcgttgccg cgctggaaca gggcgtcgta gatcgccatc ttggacggga agtactggta
     1681 cagcgacggc ggctgcatgc cgagccgccg cgcgaccgcg gacaggctga gcgccgcgac
     1741 gccctcggtc tccatcagct cgatggcgac ctcgaggatc tcctcgatgg tctcctgccg
     1801 gcgacgggta cggcggtcaa ggccggctgt actgctcatg gaatgaggaa aacctaagac
     1861 cattagggaa gtcaataccc cgtaggtgtc gagttggaat gtccctcccg gcgcgtagtg
     1921 tcttggcatg tgcagaaaca tcacggttct ccggggactc gagccggccg cgacctctga
     1981 ggagatctac gcggccgcgc tgcagtacgt gcgcaaggtg accggcgtcg gctcgctgag
     2041 ctcgaccacc cgcggcccga tcgagcgggc cgcggccgag gtcgccaaga tcaccgaaca
     2101 gctgctggcc gagatgccgg agcgcaaggt gccaccgcag accgtgccac cgctgcggcg
     2161 tcccgaggtg cgggcgcggc tcggtctcga ctgagagcca cctgtggggc aggaagcggg
     2221 caccagccgc cgccgtcaag gactggtgct cgggctgatc gtcgtcggcg ttctgctgtc
     2281 gttgacgaat accaacgcac agagcgagtt ggtgcgccgg cgggaggaca cgtgcgacgg
     2341 gtcgctaccg ctgccgaccg gcgcgtatgt gctggggttc accgggctcg cagtcggcag
     2401 cgtcgcgctc gtactgctgg tgcgctggtt cgggggaagc cgtgagccga tcgcgctcat
     2461 cctcttcgcg accgcgatcg ccgctgtcgt cgtcgagatc ttcgccgtcg tgaccgcgtt
     2521 ccaggagggc cagccggtct acccgatgtg cggcggttag ccggccacct gcgggaggaa
     2581 cgccgcgagc gcgctgatca gcaacggcgc gaatacgctc aagatggtca gcgggttccg
     2641 caagatcgag atgtccagat ggagcagctg ctcgatccgc tgccgcgact ccacccactc
     2701 cgcggtgggc ttcccgtccg gcggtagtgg acaggcatgc tcgaccaact gctgcgcccg
     2761 attccgccac tgcacagcca tcggtacggc gatgatcgaa agcccgagcg cgaacaacaa
     2821 gccgtacatc agcacattcg ccggcgggaa ctcgtcggcc cgctcgggat aggccgcgac
     2881 gaacgcgccg cgcaaggcac ccgagctcgc gacggccgcg accacgccga aggtgaaggc
     2941 acccacgctg aacaacagca gttgccacag ttgctcgagc cgctcgaccg cggaccggag
     3001 gtgctccgat tcgcccggct cgtcctgcat ggcggccatg tagttgttct ccagatgacc
     3061 gttcgtaccc cgggggatct ccttctccag gtcgtggcac tcggcatgcg ccagccagac
     3121 gatggtcagc cagggaacgc tggcgaccat cccggcgatc aggacagtgc gggtccgcca
     3181 cccgagaccc tgcacaggca gttcgaggcc acccacgggg tggcgcaccc ggaaccacac
     3241 gaccgcgccg gcaccgatgg ccgccagcag caggtagcga cggcgacgcc cgggggcccg
     3301 gaagatgccc cactcgttcg gacgctgcaa gatccggagc gcctggacgg tgaggaccac
     3361 gaacaccgca agcgccgcac cggcgatggt tcgccagatg gtccacggca ccccctccac
     3421 aaacgcgtcg ctttccttgc cgcccttcga tgccgcgatg ccgagcagcg cggtaaaccc
     3481 gaacagcagc gcgaacacga tcatgctccg aatcggcggt ggcagccgga cccagaacgg
     3541 atcctccacc agctctttcg gcagttccac cggcatcgcg ccccctcacc ccagacttgc
     3601 cccaagtttc ccggttcgcc ggttcgcccg tcgtccgaat ccagcgcgtc ctgccctttc
     3661 gggcacccgc atttgatggg ttcacccgtc aaatgcgggg ttcccccacc gcatgccagc
     3721 ggggaaccca caacccgatc ggtgaaccca tcaaatgggg acggatgggc ggggtaaggt
     3781 cgcacctggg aaacggttac ctaggaggcg ggcatgcggt tcgcgatcaa gaccaggcct
     3841 gagcacacga cgtggcagca gttgcgggat gtgtggatcg ccgcggacga cttcgagatc
     3901 ttcgagtccg cctggcactg ggatcacttc tacccgctca gcggtgacat ggccgggccg
     3961 aacctcgaag cctggacgac gctcgccgcg ctggcccagg cgacgcagcg gatccgcgtc
     4021 ggctgccagg tgaccggcat gatctaccgg catcccgccg tactggcgaa catggccgcg
     4081 accaccgaca tcatctccaa cggccggctc gagctcggtg tgggcgcggg ctggaacgag
     4141 atggagacgg ccgcgtacgg catcgagctg tatccgctga aggagcgctt cgaccggttc
     4201 gacgagggtg tgcaggcgat gatcgcgctg ctcaccgaga aggtcgcgaa cttcgacggc
     4261 aagtacatca agctcaccga cgcgtactgc gagccgaagg ccgtgcagac tccgcatccg
     4321 ccgatcacca tcggcggcaa ggggccgaag cggacgctgc gtgcggtcgc caagtgggcc
     4381 cagcactgga acgtgatcgt gccgagcccg gaggagtgga agccgctcaa ggacgtgctg
     4441 gtcaagcact gcgaagacat cggccgcgac gtgaacgaga tcacctgctc ggtcaacgtc
     4501 cgcatcgacg ctgatcagcc cctcgatgca gcggtcgcgt cggcggcagc gtacggcgaa
     4561 gcaggtgtcg acctggtcgt gatgaacctc ccgctcgacg ccgcgccgtc cgtcgtcgaa
     4621 cccctcgcca aggcgctggc tccgctggcc taagtttggg cccgtggacc gggaggagta
     4681 cgtcgaggcg gtgctgcagg cagtggagtc gatcccgcct ggcagtgtgg cgacgtacgg
     4741 cgacatcgcc gagtacgtcg gacagggcgg acctcgccag gtcggtgcgg tcatgcgcga
     4801 gtacggcgga ggcgtcgcat ggtggcgggt catccgggcc agcggcgtcc ccgcggacga
     4861 ggtgggcgac gaacagctcc acctcctccg cgccgacggc gtccgcatca ccaacggccg
     4921 cgtcaacctg cgccaggtcc gctgggaccc ggaaatccag gagcattaac aacctcgact
     4981 tggcacactg cgaggggtga acacctggtc cgtcaagccc gcgtccgtcg actccgccga
     5041 ggcgctggcg ttgcttcgtg acttctacat caccgtcgcc gatcgctgga gcacgctcta
     5101 tctcggccgg ccgaacactc ccgaggagat cgagaccggg ctcgccgagt acccgagcac
     5161 acacctcgcg ccgccgaccg gcctgttcct catcggtcga tatggcggtg ccgtcgccgg
     5221 ttgtgtcggc ctcaagatca aggatgccga cacggtcgag ttgtcccgcg tcttcgtccg
     5281 gccggcgtac cacggcacgg gcggtggcgc cgctctgctc gccgccattg agagtgcggc
     5341 ccgcgagctg ggcgctagtc gcatcgtcct cgacacccgc ctcgacctga gcgaggcccg
     5401 cgccctgtac ctgaagcacg gctaccagga gatcccgccg tacaaagaag agaagtacgc
     5461 cgaggtgttc tacgccaagg aactcgccgg accgccaggc catcacaact gagctgccgg
     5521 catgggcctg tgcgtggggt aggcccgggc gtgctgattg tgatggcctg caggtccgcg
     5581 cgtccgcagt gcggagaggt ttggggtcgg cggtgtgtgc cgtcggggtt tgtcggtggg
     5641 gtctggtgag atgtggcggt ggtcagcaga caggggtccc gataccggtt ggtgcgggcg
     5701 gaggggcgca gcgcggatgc tcctgttctg gatgcggatc agcaggcggt ggtggatcat
     5761 ccgggcggac cgctgctggt gctcgccggg cctggaacgg gtaagacgac gacattggtc
     5821 gaggcggtcg tcgatcgggt gcgcaatcgt gggctgagcc ccgacgaggt gctggtgctg
     5881 acgttcgggc gcaaggccgc gaccgagctc agggatcgca tcaccggccg gctcgggcgg
     5941 accacgcggg tgatgccgtc gatgacgttc cactcgttct gctatgcgtt gcttcgacgc
     6001 ttcacacccg ccgacgcgtt cgacgtaccg ctgcgacttc cgtccggtcc ggagcagtcg
     6061 ctgcggttga gcgaggcgct gtcaggcagt cgcgaggttg gcgcggtgca ctggcctcgg
     6121 agcttgcatc cggccttgaa gactcgtggg ttcaccgacg aggtccaagc cgtgatcggc
     6181 aaggcgcggc agctcgggct cgaccccgag gatctgtccg cgatcggtcg ttcggcggaa
     6241 cgggcggagt gggtcgcggt cggcgacttc ttcgaggagt acctgcagat cctcgaccac
     6301 gaacaggtcc tggattactc cgagctgatc caccgcgcgg tgatcctggc ccagcaaccg
     6361 caggtccagg ccaaactgcg gaccgagttc aaggccgtct tcgtcgacga ataccaggac
     6421 accgatccgg gccaaaccca gctcctgcaa gcgatcgcgg gcgacggccg cgacctcgtc
     6481 gtcgtcggcg atccggacca atccatctac acgttccgcg gagccgacgt ccgcggtctg
     6541 ctccggttca ccgaggagtt ccgtacggcg gacggcgcgg aagccgccca gatcgccctc
     6601 ggcaccacca gacgattcgg tacgacgatc tcccgcgtct cccgcaatgt cgtcagccgg
     6661 ctgggcgtgc cgggcactct cgaccgcgac accttcgaac gcttccgcaa tccagacgcc
     6721 agtggctgcg tctacggtca cggcaaggtc gaggccaacg tctactcgac cagcggcgcc
     6781 gagctcgagc acatcgcgga cctgcttcgg cgcgcgcatg tccaggacgg cgtcggctgg
     6841 aacgagatgg cggtgctggt cagatccggc agtcgctcga tcccgccctt gcgtcgtgct
     6901 ctggccgcgg ccgggattcc ggttgatgtg gccggcgacg aactcccgtt gtcgcgtgag
     6961 cccgccgtac gtccgatgct tcttgctttg cgtgccgtcg cggatccgtc cacgttgacg
     7021 gtcgacgtcg tacgggcgct ggcgttgtcg ccgttggggg cgatggatgc ggggcagttg
     7081 cggcggttgg ctcgggtgct gcggcggcgg gaccgggagg cggccggtgg gcagcggttg
     7141 ccgcggtcgt cggacgagct gctgcgggag gcgttgctga atccgctgct gctggacgcc
     7201 gaggcgtcgt cggcggaggc acggttcgcg gcgctgggtg aaaggttgct gaaggcaaga
     7261 aatatcgtga ccgcgggcgc ggcaccggac gaggtgatgt ggtcgctgtg gtcggattcg
     7321 ccgtggttgc gccggttgcg cgcgcaggcg aactcgggtg gtgagacggc gcgaacggcc
     7381 aaccgggatc tggactcatt gtgtgcgttg ttcgacgccg cgagccgggc ggaggagcag
     7441 gtcgggttca agggggtgtc ggcgtttctt tccgagctcg agtcactgga catcgctgcg
     7501 gatcaccggt tcgacgcgac gtatcgcgag gccggcgtac agctgatgac ggcccaccgg
     7561 tcgaaggggc tgcagtggcg gctggtggtt gtggcgagtg tgcaggaagg gcagtggccg
     7621 gatctgcggc ggcgggggtc attgctggag ccggatcggc tcgggccgga cggtttggtg
     7681 gagcccttgt cggccggggc gttgctggcg gaggagcggc ggttgttcta cgtcgcgatc
     7741 acgcgggctc gggagcggtt gatcgtgacg gcggtgcagg cgccggaggc ggatggggat
     7801 cagccgtcgc ggttgttggc cgagctggac attccggtga agctggtggc tggtcgtccg
     7861 cggcggccgt tgtctttgca cggtctcgtc gctgatcttc ggtgtgtact cgcggatccg
     7921 gcgtcgtcgc cggcgttgaa acgggtcgcg gcggatcggc tggctgtgct ggcggatgcg
     7981 gcggacgatc gcggtcagcc gttggtgccg acggccgacc cggcgcggtg gtggggtgtg
     8041 cgggaacgaa cgcggtctgc cgtgccgatc gcgaatccgg agctgccggt gccgctgtcg
     8101 gggagcgcgc tgacgacgat cgtggactgt ccgttgaagt ggttcctcac ccggcgagcg
     8161 ggtggtgaaa cgcccagtac gtcggcgatc gggttcggcc aggtgctgca cacgctggcg
     8221 gatgcggtcg cgagcggggc gttgccgccc gacgcggacg agctgaacgg gtggctcgac
     8281 aaggtgtgga cgcagctcga gttcgagtcg gcgtggatct ccgaccggga gcgggtcgag
     8341 gccgagcagg cgttgcggcg gttcgtcgcg tggcatcagg ggcggccgga tcgggagttg
     8401 atcgggaccg aggtggagtt cgacgtactg ctgccggatg ccgacaaacc cgctgtacgg
     8461 gtgaaggggc ggatggaccg gatcgaggcg gactccgagg ggacgatccg ggtggtcgac
     8521 ctcaagaccg gccggtcgat gccgaccaag ccggcgctag agcggcacgt ccagctcgcg
     8581 atctaccaac gcgcgatcgc ctcccggcaa cttcccgtcg tcggccagga cccggtcgcc
     8641 ggcggtgccg aactcgtcca gctccgccac gacgacagcg gcttcccaaa ggtccagcac
     8701 caaggcccgc tggaatcgga cgacgacggc cgcacctggc tggacgaagc cgtcgacgac
     8761 gccgaggcaa tggtccgctc cgaggaattc gttgccaaac gcaacgacgg ctgcactcgc
     8821 tgcgaagctc gcccgctctg ccccatccaa cccgaaggcc gggaaatcct ctgatgcgcg
     8881 ctcacctgac aactacagct gagttgtgtg atctgctggg gattccgttt tctgatcagc
     8941 agttggcggc gatcaccgcg ccgctggctc cgggtgtgat tgtggcgggg gctgggtcgg
     9001 ggaagacgac ggcgatggcg gctcgggtgg tgtggctgat ttgcaccggg caggtgaaac
     9061 ccgaggaagt gctggggctg acgttcacca agaaggcggc gaacgagctc gacgtacgga
     9121 tccgcgagga tctgaccaag gccggcgtac tcggatcgac cctcccgaag gaccagcacc
     9181 cgatcctcgc cgcgcacctg cgcagcaaca tcccgaactg ggagcaggag gagcccggcg
     9241 agcccgtcgt ctcgacgtac cacgccttcg ccggcacgct gatcgccgag cacggccttc
     9301 gcctcggtct cgaacccgac gcccgcgtcc tcgccgacgc gacccgcttc cagttggcgg
     9361 gtcgcgtcgt acgacgatcg tccgggccca tccggttcgc gtcgcaccac gtgccgacgc
     9421 tggtcaacag cctgctctcg ctcgacggcg agctggcgga tcacctgctg acggcggacg
     9481 ccgtacggga gcatgacgag ggagtacgac gggaagtcgc ggcggcggcg aagcaaacgg
     9541 tcgaggtgcg caagctcgcc gagactgcgt tgaagcgcgg cgagatcctg cagttggtcg
     9601 aggagtacca ggcgtacaag gccgagcgcg gcgtcgtcga cttcgcggat cagatggcgc
     9661 tcggcgcgcg gctggcggag gagtgcccgg aggtcgcggt cgtcgagcgg tcgcggtaca
     9721 aggtcgtgct gctggacgag tatcaggaca cgtccgtctc gcagcggcgc atgctcaccg
     9781 ctttgtttgc gggcccaggc gggcaagggc atccggtgac cgcagtcggc gatccgtgcc
     9841 aggcgatcta cggctggcga ggtgcgtccg tcgcgaacct ggacgaattc cctgagcact
     9901 ttcccaatgc ggacggcaca ccggcgcagc gctacgtgct cagcatcaac cgccgctgcg
     9961 gcagccgcat cctcgccgcg gccaaccagc acgcgaccga gctctacgag cagcatcccg
    10021 gcgtgatccc gctcgaagcg ccgccggacg cgcccgaggg agcgatcacg gtcgggctgt
    10081 tcgagacgcg ctcgcaggag atcgagtggg tcgccgacgc gatcgttgcc gcgcacaaga
    10141 cgccgaaccg ccggtggaag gacatcggca tcctgatgcg tacgaacgtc gacctcagcg
    10201 cggtccacga agccctgatc gcgcgcaagg tcccggtcga ggtggtcggc ctcggcggtc
    10261 tgctcgccct gcccgaggtc gtcgacgtcg tcgcgacctt gcaagccgtc aacgatctga
    10321 ccgcgaacgc ggcgatgctg cggatcctca ccggtccccg ctaccggatc ggccatcgag
    10381 acctcgcact gctggcgaac cgctcccgga ttctcgccga cgccggcgac cgtccggcgg
    10441 ccgacgacct ggtcgcagct ctcgacgccg ccgtcgccgg catggattcg accgaggtga
    10501 tctcactcgc cgaggccgtc gatgatccgg ggtcgctgga gtactcgccc gacgctttgg
    10561 tccgcttcaa ggaactttcg gccgagttgc gagagttgcg cgcccacgcg gcggagccgc
    10621 tgctcgacct ggtccgccga gtgatcagta cgatcggcct ggacgtcgaa ctcaccgcga
    10681 cccccgagca cgtcgactcc gcccgccgcg atcacctcgc cgccttcttg gatgccgtcg
    10741 gcaactttgt ctccaccgag tcggacggtt cgctggacgg cctgctggcg tatctggccg
    10801 ccgaggagga gtacgccgcg ggtctcgacc tcgccgtacc gagtgaagcc gattcggtga
    10861 agctgctcac cacgcaccgg tcgaaggggc tggagtggcc gatcgtcttc gtgccgacgc
    10921 tggtttcgaa ggtattccct tcggatcgtg ggcgggacaa gtggacgacg aacgcgaagg
    10981 tgctgccgtg gccgctgcgc ggtgacgccg acacgctgcc cgactttcac gatctgtcca
    11041 acgccgggct gaaggcgttc gcggacgagt gcaaggacgt gaacgcgctg gaggaacggc
    11101 ggctcgggta cgtcgctttc acccgggcga aggagatcct ggtcgcgacc gggcactggt
    11161 ggggcccgac gcagaagcgg ccgcgcgggc cgtcgtcgta cctttctctc ttgaagcagc
    11221 acgccggcga gcgggtgatc tcgtgggccc ctcagcctga gttgtctgag gagaatccgg
    11281 agctcgcgga gcagacccag gcgccgtggc cgacgccgta cgacgctgcg tcgtacgagc
    11341 ggcggctgga agcggcggcg ctggtttctc ttgcacgcgc ggagggtccg tcgctggagg
    11401 cggaggagtc gctcctgctg gacgagcagg cgacggtcgc acggtgggat tccgagatcg
    11461 agcgattgtt gtccgaggca agggaaagcc ggagccggaa ggcgtacgac gtcgcgctgc
    11521 cggccgcgct gtcggcgacg caagtgatgc ggctggcgaa agacccggac ggtctcgcct
    11581 cggaacttgc ccgcccgatg ccacgcaaac ccaaccgggc cgcacgtttc ggcacccgct
    11641 tccacgcctg ggtcgagagc tatttcggcc agcagctgct gctcgatccc gacgacctcc
    11701 ccggcgccgc cgacgaaggc atcgtcgacg acaccgacct gaccgagctg atggacgcct
    11761 tccgcaccgg cccgtacggc gaaaccacgc cgtacgagat cgaggccccc ttcgccctgg
    11821 ccatcggcgg ccgggtcatc cgcggccgca tcgacgccgt ctaccaggtc gtccgccccg
    11881 acggctcccg cggctacgac gtcatcgact ggaaaaccag ccgctccgaa accgccgacc
    11941 ccctccagct agccatctac cgcctcgcct ggtccgaact ccacaacatc cccctgcaca
    12001 acgtcaccgc cgccttctac tacgtccgca ccgccgacat catccgcccc gccaacctcc
    12061 cgggaagaca ggaactgatc accctcctca acggatgagc tccgccggaa caaccttcac
    12121 aggaaaggga atctcagcct caaacacctc atcctcactc accaccgccc gctcgacata
    12181 cctaccctcc tccaactcga gcgccgtcaa ccgcacctcg tccggatcga acatccagta
    12241 cgacgcaaca ccggccgtct cgtagagctt gcgcttgaac acctggtcga ccgtacgggt
    12301 cgccggcgaa agaatctcaa cagcaagcag cagcggcccc tccagccatt gcactccgat
    12361 gtcgtcacac cgaaacacca ccagatcagg caccagcgcc agacgactgt gcggccgaaa
    12421 ctcaacccca tgcaagacct cgagatcctc agggcagacg ggtgctagta ggaagcacag
    12481 ctcgcccaga gctcgctgat gaatcgtcgg tggagttgat gtgattatga gaactccatc
    12541 gactagctca taccgcatgc cgtcgtcagg cgtgacctcg agatccgccg tcgtgaattc
    12601 atctggttcg atcggtcgca tgctccaacc gtggaccggc tcgaaccgag tcagaagggc
    12661 agatcatcat ctgcccgggc cttgccctga cctcagcatt cgcgtagcaa ctcggccggg
    12721 acgattcgaa ccggaaacgg cagctccgcg tcgaacgctt tctcgccggt gactacatcc
    12781 cgctcgacgt acgccccgtc caccagctcc aggacggtca gcgcctcctt gtcgggatcc
    12841 aagatccagt aggagcgcac accggcctgt tcgtacacac cacgcttcaa gagcagatcg
    12901 agcatcttgg tactcggtga caggatctcg accgcgagaa gcagcggctt ccgtaacttg
    12961 tccgacccgc gatcttcggg attgcagacg agcacatcgg gctggagcga gcgctccgac
    13021 gtcggctggt aatcgaacgg tgcgacgagg acctcgaggc ctgcagggca ggagaggttg
    13081 agcttgccgc cgaggcggat gacggctctc tggtggatcc tcgaaggtga aggcgttacg
    13141 cacagtccgc cgtcgatgat ctcgcgccgt ctcccgtcgt caggcgcggt ctcgagatac
    13201 gccaacgtgt aggggcctga ggcaatgggt tccacggggg tgcccccttc ctggtcacac
    13261 gaccagcatg gtggttcccg aggagtggtt ggtgcgattt cggcgatctg cccctatctg
    13321 ccccgggttg cccttggatc tgccccgtca tctcgtcaga tcggctgggg tgagggtgac
    13381 tgggaagggg tgggtggcgt ggaaggtctc ctctgactgg agtgcggcgc ggcaggtata
    13441 gcccgtttct gtcagctcca ggatggttag ttcgtggtgg gtggggtcca ggagccagta
    13501 ggaggggacg tggtgggttt cgtagagggt tcgtttgagg actacgtcgg tggttcgggt
    13561 ggtgggggag aggacttcta cggctagcag gggtggatgt tgcaggagtt ggcggccggc
    13621 gtcttcgcgg cggcagacga ggaggtcggg gcggagggag atgtcgacgg cggggcggaa
    13681 gtccagggag cctacggaga cgagcaggtc gggtgggcag gcttgtttca ggacgaccat
    13741 gagcgccaca acggcggcgt ggtgggcggg tggctgggcg cctgtgatca gcaggcggcc
    13801 gtccacgacc tcgtagcggc gtccgtcgcg tggtacctcg acaacctgtt cgctcgtcac
    13861 cccatcagct tgaccgattt cgccgtaccg ccgcgggagt tatccacaac cctcgctccg
    13921 cagcgtagag gtccggcctt gagaagccac cgatcatttc tcggcgccga acgtggttgg
    13981 cgggttctca aggtggagcg tcagcctgcg gcttccgtga cgagtggatt gtccaaggtg
    14041 cctacgaact ggagtgagcc ggcgacgtcg gtcaggtcga ccatttgctg gttgttcttc
    14101 agttgcaacc tgttcagaca cgacagcgcg aacgaaggcg cgaagatgtc gtacttcgcg
    14161 aacgccgaag ccaactcagg tgtcgccgcc tggtagtcgc gcactgccga cgcgaccacc
    14221 gaccagaact ccgcgggcgc cagcagtccc tcgcggtcga gcagcggtga gaggaagcgg
    14281 aagatgcagt cgaagacgtc ggtgaagatc gacagcagct tctcgtcgtc cggcacctcg
    14341 gcgcggacgc gttcggcgtc cggcggcagc ggtgtcgccg ggctgagcac cgcgatctcc
    14401 tcggcaatgt ccttcatgat gacccgggtc ggcaccgagt tccgcaagac gaggatcagg
    14461 ttctcgccgt ggggcatgaa gaccagttcg tacgcgtaga agctgtgcag caacgggatc
    14521 agatagacgt cgatgtacgc gcggaaccag tcggccggcg ccaggcccga ggcccggatc
    14581 agcgcggcgg ccagcgaggc gccgtgccgg tcgacatgca gcaggctcgc catcgtggcc
    14641 agtcgctcgc ccggctccag cgccggcacc gggctctccc gccacaatgc ggacaacatc
    14701 ttccggtacg gcgaagtctt ctcggtggcg gattcgtagt accggttgtg gtacccggcg
    14761 gccgcgatct cgcgcaatac ggaaaagccg tatcgcttga ggaccaggtc gttctcgacc
    14821 aagcggtaca cccagtcgtt gatcgccggc gtcgccgcca tgtacgtcgg cgacagaccg
    14881 cgcatgaagc ccatgttcag caccgacagc gccgtcttca cgtagtggcg cgacggttcg
    14941 gaccggttga agaaggtgcg gatcgactgc tgcggctggt attcgtcgtc actcgacccg
    15001 agctggatga tgtgccgctg cgcgatatcg gccgcgaacg tgatcgacgt cttgtgctcc
    15061 cattgccacg gatgcaccgg caggtagacg tagtcggccg gatcggcgcc gacggcaacg
    15121 atgcgctggg cgaaccggcg cagcgcgtcg tagccgagct cggtctgcag cagttcgtcg
    15181 tacgtgatcg tcgtgctgtg cgagatcgtc gtccgatcgc ggcgtacggc gatccaggtc
    15241 agccgcacgg cttgccggtc tcgggcgcga aggcacggta gtcggtggcg ccgaagccga
    15301 gccgcccgtt gttcgcgacg aagcacgggt ggccctcggt catcgcggcc tcgatggtct
    15361 ggaaatcggc ggcgaccaga tcggaagcgg tcagatcagg cttgctgagc ttgtacgacg
    15421 cactcgccag cgtgctgctg atttcctcga gatacaccgg cagcatctcg gcgccgatgc
    15481 cgagctgctg gtgaaactcg gtgatgaagt cgagcgcgtc gaccggagcg gcttgaccgt
    15541 cgacgaatcg ttcgatgctc gcggcatcga cttcccaatg gttgagcgga taaagcttgg
    15601 cggtaaaggt gtattggctc gtcccaccag acagttggta tccgttgccg gtggcaaccg
    15661 gttcgagaat gcgttcgtga atgaactcgg ccagggcctt gcggaccagc gcgcgattgg
    15721 cgacggccca ggtgtccggg ttgagatgct cggtcgtcat ggttcagccc gcctcgttca
    15781 tccgggtcgc ttcggcgtac tggtcgcggg tgcacaaact cagccaggcc tgcttgttcg
    15841 gcaggtcgac gatgctgtgc ttgcggaacc ccatccgctc gttgagcgca tggatcttgg
    15901 tgttgcggac gtccggctcg accacgatcc ggtcgatcag cgggtctctg aacaggcagt
    15961 ccaggatcgt ctcgaacacc gcgccggtga agcccgggat gcgctggtcc ggcggtgcga
    16021 ccagtacgtg catgccgatg tcgccgggcg cgacgtcgta cagcttgccg accgcgtcgt
    16081 acgacggctc gtagcgctcc atcaggaacg cgggccggcc gtcgtgctca ccgaggaagg
    16141 cgcggtgatg accggattgc gcgatccgca ggtactcggc gtggacgtcg tcgacggagg
    16201 cgttcagcag gccccagtag cgcgcatagg gttggctgac ccagccgtgc agggtggtca
    16261 cgtcctcggt caggtcgaac ggccggaggc tgagggtacc gataccggcg aagaagcgcc
    16321 ggtgtgacag tgctctggtc atggcggtct gctttcgagg tgggcgaacc tgttagctaa
    16381 gccttacctt acttaccgac gaatccgccc ttgacagggg gtccgtatcc tggcgtcccg
    16441 cgcgacagcg tgctgaaggt gggcaggcag ccggacgagc ggactggtgc gctgatcgct
    16501 ttgctgagcg ccctgaacgt cgtaccgaag gtggtgaccg acgcagtcga caagagggcg
    16561 ctgaggaagc gggcgaagga gatcgccgcg tctgattggg cggccgatgc ggtgaagaag
    16621 gctgtcgcgg agatgcaggc cgcggtcacc accgcggttg tcgtctcggc gagcgccgcg
    16681 gcctcatccg gcagctgact ccgcggcgga caggcgggcc ttgatgtcgg gcttgaggac
    16741 tttgcctacc ttggagcggg ggaggtctgg ccagagcagt acttctttgg gggccttgac
    16801 gctgccgatg cgtgccttga cgaaggagat cagctcaacg gggtcgaccg tggtgcccgg
    16861 ctggggttgg acgacggcca ccacccgctc gccccacttt tcgtccggtt ggccgatcac
    16921 cgcgcagtcc tggaccgcgg catgggccat cagggcctgt tcgacctcgg tggagtacac
    16981 gttgaagccg ccggtgatga tcatgtcctt ggcccggtcg acgatgtaca ggtagttctc
    17041 gtcgtcgagg tagccgatgt cgccggtgtg atgccagccg tacgcggacg ccgccgcagt
    17101 ggcctccggg ttgcggtagt agcccttcat gaccagtgag ccgcgtacga cgatctcgcc
    17161 ccgctcgccg cgccccagca gtgaaccgtc cgcgcccatg atcgccgtcg tcacgagcgg
    17221 cgacggccgg cccgccgacg acagccggcc caccgcaatg ttgccagagg catcgaaatg
    17281 gtccgacggg ggcaagacag agatcatcat cggcgcctcg gtctgcccga atagctgggc
    17341 catcaccggt ccgatccggt gcagcgcctc ctcgagccgc gacaccgaca tcggcgcggc
    17401 gccgtaccag aagcaacgca gcgacgacag atccgtcgca tcgagctccg gagcgccgag
    17461 caccatgtag atcagcgtcg gcggcaggaa ggtatgcgtg acgcgacaag tagggatcaa
    17521 cgacaggaac aagtggacgt cgggcgtccg catgatgacg acctcgccgc cgaaggccag
    17581 gatcggaaag cacagcacac cggctgcatg cgtcaacggc gcgagcgcga ggtagacggg
    17641 ccggtcgccg aacggatagc tcatcagcgt cagcgccgtc atcgtctcca ggttggtgtt
    17701 gctcagcatc acgcccttgg gccgccccgt cgtaccaccg gtgccgacga tcatcgcgag
    17761 gtcgtcagga tcggtcagat cgggtgccgg ctgggacgcg gaaccgcaga acgcgtccca
    17821 gccgtccggg tcgtccaagc agacgaaggt gtgcaccttc ggcagcgcgt cccggatccg
    17881 gtccaccagc ggcgcgaacg ccgcctggta gatcagcact tcacagtcga actggtcgag
    17941 caactcgcgg ttctccgccg cctcgttgcg cgggttgatc gggcaccaga tcgccccggc
    18001 ccggctgatc ccgaacacgc agctgaacgc gatcgggtcg ttcgccgcca ggatcgccac
    18061 cttgccaccc ggacgtacgc cgctcgccgc aaggccggct gcgatccggc cagacagctg
    18121 ctggacttcg gcgtacgtca gagtctcgcc gtcggtggtc aggcaagctg cgcccggatc
    18181 gagcgaggcg cccttgtcga ggtagtcgac cagtcgcaca gcaactcctt agtgcagcac
    18241 tgtcagctgt ggttcggaca ccaggccgaa gctgcgcagt acgccgagca gctcccggtg
    18301 gccgaatgcc tggcagccac tggcgaagcc gactcgcttc ggtggtgtct gcagcagtga
    18361 gtacgccgcg tacgcctgca gcagaccggt ctgctggtag ttgctgttcc cgtggatgac
    18421 gcagtgagcc cggccgagcg gaccggaggc gtggacggag tccagtgact tgttcacccg
    18481 tgggttctcg cgtggcggca tctggttcat cacctggcgg gctgtctcgg tcagggccgc
    18541 gttgcgatcg tccggagcca tgtccttggt cgcttccaga gcggcggcga cgatctgcgg
    18601 tacgccgttc atcagtgcgg cgttgaagac tccaccctgc gccttacagt tggccactct
    18661 gggatcacgc ttgaaccata ccggatgcga cgtaccaccc cagggcagcg acagcgcgag
    18721 ttcgtgttgc ccgggcacca ccagcggcac aaggccctgc tcgggaaact cgacgtacgc
    18781 gttctgctcc aggtagtgcg ctttcgacgt ggctgcgttg accaggatgg ttcgggtcga
    18841 cgcgatcgtc gggctgccgc cccagaacac cgcaatgtcc agggtgtcca ggccgggctg
    18901 ctccaggcag agctgtgcgg cgatctcgcc ggtggtgtac atctgcgcga tacctggagc
    18961 cagcagcaga ccggctgcgg cgaagtcggc gccgtacttc tcgtcgcagg tgatcagcca
    19021 gtcctgctcg ccagtcgtgt cggtgtagtg cgctccggcc gccagggccg cctcgaccgc
    19081 ggcggggccg agttcgctga acggtccgac cgtgttgagc actactgagg cgcctttgaa
    19141 cagatcggtc agtgcgtcga cgtcgtgctc gacaccggcg acctcgtagt cggccgtctc
    19201 gatcccggcc acgtgggagt ccatcgactc cttcagcttg tcctcgctgc ggccggcggc
    19261 cacgaacggg acgtgatact ggcggaggta ctcacacacc agccggccgg tgtagccaga
    19321 ggcgccgtac acaacaacag gtttgctggt catcacatcc ccattccgcc gtcgacgggc
    19381 aggccgatgc cggtgatgaa gcgggcctcg tccgacgcga ggaagacgac tgcgtcggcc
    19441 atgtcggtga cttcgccgag ccggccggca ggtgtcagcc cgaccactgc ggcgactgct
    19501 gcctcggggg actcgaacag gccgagccgt gcgacgtcgt tcgccagtcc tgcgcccatt
    19561 gccgtcggca ccaagccggg gtagatgcag ttgacgcgta cgccgtaccc gagcttgccg
    19621 gactccatcg ccgcgacccg ggtgagccgg tcgaccgcgg acttggtcgc ggagtagacc
    19681 gcgatgccgg ggaaggcgat ggtggcggcg accgaggcga cgttgacgat cgcaccgccc
    19741 tgcccggcca gcccgccggg gcgcatcgtc cgcaggcccc acttgagccc gagcgtggtg
    19801 ccgagcacgt tgacgtcgag catcttgcgg atgtcgtcgc tggtcacctc ggtgagcagg
    19861 ctggtgatct ccacgccggc gttgttcacc aggatgtcca gcccgccgag gatgtcgctc
    19921 gccgcgacga cggcgttctc ccagctgccc tcgtcggtga tgtcgtgggc gacgaagccg
    19981 ttgccggcgc cgtactcgct gtccagtgcg tcggcgacgg cctcgccgag gtccttctgc
    20041 agatcgctga tcaccacttt ggcgccggcc gccgcgagcg ccttcgccat tccttcgccg
    20101 agcccctggg ctccgccggt gacgagtgcc ttgcggccgg tgagatcgat tccgcccatc
    20161 tgaagctcct tgctcgaagg ggaccaccgg aaatcactct gatatttcct ttgacagtcg
    20221 tcaagacttt gcttgacact tgtcaagaaa tctcctcgcc acggatgcgc ctgatccgtg
    20281 gcgaggtact ctgacgcgaa cgaaccggcg agagtggggt ggtgcgcgtg agctcagcga
    20341 gcgcggcgga gccgagccgg ccagcccggg tctccgggat cgacaagatt gagcgccgcc
    20401 gggtcgcgct ggccgagtcg gcgctgaaga cgctcggcga gctggggtac gcgcggacca
    20461 gcctgcgcga gatcgcgaac aactccgagt tcacgcacgg cgtcgtgcac tactacttcc
    20521 gcgacaaggt cgacctgatc agctactgcg tgcgctacta caagacgaag tgcgcgcagc
    20581 ggtacgacga agtcgtggag acggccgggt ccgcggaaga gctggcggcc ggcttcctga
    20641 gcaagatggc acagacgctg gtcgaggaaa ccccgatgca ccggctctgg tacgacctgc
    20701 gcgcccagag catgttcgag gagcagctac ggccagacgt cgccgcgatc gaccagctgc
    20761 tggaggagat gatctggcgc atcctcaccc ggtacgccga cctctccggc accgaaccgg
    20821 ccgtcgacgc ccccaccgcc tacgccctgg tcgacggcct cttcgaacag gctgtcgtca
    20881 actacgccgc cgaccctgcg ggggcgcggg acctgctgac tggcagggtc gagcaggtcc
    20941 tgccgaaact cgtctattca gcctgacagt tcgtcttgca gagcttgtcg gtcagcgtca
    21001 ggtgtacgcc gggctcgtcg gtgtccacct cgacgatgta gtccaccagc cagtcaccgg
    21061 cggtcagctg ggccgaggcc gtgctcttct gcttgccgaa ccagtccgtg atctgctggc
    21121 gctcgttgat gtgtgcgatc tccagtgcct gcggcaggac cttggcgatc gcggccgacg
    21181 ccttctccgc cgggccggcg gagtgcagcg acaccactgg tggccgtggg tggtttccgg
    21241 tcagtaccca gaccgatgcg gctcccgccg tacaggtggc gtaggtgacg tcggtgctgc
    21301 acttgtagcc ggcgttggtg aggccggtga ccacttgggc cgcgttgatg gtcggcaaca
    21361 ccgcgggagt cgtcgtcgga gtgctgcttg cctcgggcgt gccggcgtcg gagccgtccg
    21421 agccgttgga gctgttcggg ccgttggagc tgttcgagca ggcagtgagg agaagcaggg
    21481 tagccagggc ggtggcgacg cgcttcagac cggcacctcg atcgccgcat cgagagcgat
    21541 ggtgatcatc tcggagaacg tcgtctgccg ttcctccgcg gacgtcacct cgtgggtgat
    21601 caggtggtcc gacaccgtca tgatgccgag cgcccggcgc ccgaacttcg ccgccagcgt
    21661 gtagagcgcg gccgcctcca tctcgacgcc cagtacgccg tactccgccg tacgcgagac
    21721 caggtccggc cggtcgttgt agaacaggtc gccggagaac acctggccga cgtgcacgtt
    21781 cagcccggcc gcctcggcag cgtccacagt ggaccggagc agctggtagt cggccgtcgg
    21841 cgcgtactcg atgccgtgga agcgcagccg gttcatctgc gagtcggtgc tcgcggacat
    21901 cgccacgatg acgtcgcgga cccggaccga ctcggtcagc gctccgcacg taccgacccg
    21961 gatcagcgtc tgtacgtcgt actccgtgaa cagctcgtgc gcgtagatgg acgccgacgg
    22021 ctggcccatg ccggagccct gcacggagat ccgctcaccc ttgtaggtgc cggtgaaccc
    22081 gaacatgttc cggatctcgg tgtagcagat cacgtcgtcc aggtaggtct ccgcgatcca
    22141 cttggcccgc agcgggtcgc cgggaaacag gacgcgcggt gcgatctgcc ccttctcggc
    22201 ggcgatgtga atactcatgc ggggatgctc tcacggtctc ggcgcagcgc ctggctcacg
    22261 gtgccgggat atgttgagga ggtggcctac tccatcgctt ctggttccct agccctgtcc
    22321 cggtccgtac tggaccgcgc tgccgatcgg aggcgcgacg aggagtggct ggagaaggcc
    22381 tggcacgcgc cggacacgca ggtggcggtg gtggcccagg acaaactggt ggtgaccgct
    22441 gaccggaccg ctctgaagct ggtgccgtct tctgaggcgc ccgaaggtac gcgcgtcttt
    22501 ctggggatcg atcgggagtc aggagccggt cagaccgctg agggccgggc ggtgttcgcc
    22561 gtactggtcg atggggagcc agacgagtcg tacgccgggc tgcgtgagat cggcgccgta
    22621 ctgaacgacc gtgaggccgg tatcgcagtc cacgtggtcg gtctgtccaa ctggcatggc
    22681 gtgcatacgc actgcgccaa ctgtggtgag cacaccgagg tagtcgaggc agggcatgtg
    22741 cgggactgtc ctgcgtgtgg cgcgaagcac ttcccgcgca gcgacccggc gatcattgtg
    22801 ctggtcaccg acgaccagga ccgcgcacta ctcggccgca acgaggcgtg gcctgagggc
    22861 cggtactcga ccctggccgg cttcgtggag ccgggtgagt cgctggaggc cgccgtacga
    22921 cgtgaggtgc ttgaagagac cggtgtgatc gtggggcccg agatcgagta cgccggtagt
    22981 cagccgtggc cgctaccgtc cagcctgatg ctcggcttct acgcgaaggc ggtgggcttc
    23041 gagatcgagg tcgacgccga cgagatcgca gaggcccgct ggttcaccag ggaggacctc
    23101 cgtgccctgg tcgaagccgg cacgatggcc ctccccggca acatctccat ctcccgccgt
    23161 ctgatcgagg gctggtacgg cgaggagctc accggcagct ggtgatcacc agccggcatc
    23221 cgagagtcca taactcgggc gctagggatc aagcggccgc gcgcgcaggt caggcggcga
    23281 gcttctcggc gacctgggcg agggaggggt tggtcatcgc ggtgccgtcg gggaagacga
    23341 cggtcgggac cgtctggttg ccgttgttga ttttctcgac cagcgccgcg gcgtccggga
    23401 cctgctcgat gtcgacctcg gtgaactcga tcccggctcg cttcagctgc cccttcaacc
    23461 ggtggcagta gccgcaccag ggggtcgagt acatcgtgaa tgccgccatc aactggctcc
    23521 ttctgctccg gcgcggtttc tgtccggccg tccgtctagg gttgctctcg tcgtatccga
    23581 acgatgccgc aggtggtgcg cttcccaaat gtccccgtcc gtgagcgatc tcacacgatc
    23641 cgcatccgcg gatagcctct tggaggcgct cgaccctgag cagcgggcgg tggcgacgac
    23701 gctgcacggg ccggtggtcg tgatggccgg cgcggggacg ggcaagacgc gtgcgatcac
    23761 ccaccggatc gcgtacggcg tccggactgg gaccttcgac ccactgcgcg tactcgcggt
    23821 cacgttcacc cagcgtgccg cgggggagat gcgcggccgg ctcgcgcagc tcggggtcga
    23881 gggcgtccag gcgaggacgt tccactcggc ggcgctgcgg caggcgaagt ggttctggcc
    23941 caaggtgtac ggcggggagc tgccaccgat cgcggatcgc aagttcccgc tgctcaccga
    24001 agcggcgtcg cgctgccggg tccgggtgga cacgcctgcg ctgcgcgacc tcgccggtga
    24061 ggtcgagtgg gccaaggtga gcaacgtccg gccggacgat tacgcccggc tggcccctcg
    24121 ctcgggccgc acgctggcgg ctttcgaccc ggccaccatc gcccggatct tcgcggcgta
    24181 cgaagacgtg aagctggagc gcggccggat cgacctggag gacgtgctgc tctgcgcggt
    24241 cgcgctgctc gcggaggacg agcgggtggc ggcggagatc cgccggcagt accggacgtt
    24301 cgtcgtcgac gagtaccagg acgtcagccc gttgcagcag agcctgctcg acctgtggct
    24361 cggcggccgc gaggacgtgt gcgtggtcgg ggacccggcg cagaccatct attcgtgggc
    24421 cggcgccgac ccggagaacc tggtgcgctt cgcctcccgg catccgtcgg cctcggtcat
    24481 caagctggtc cgtgactacc ggtcgacgcc gcagatcgtg gacgtcgcca acaagatcct
    24541 cgacgcggcc ggtccgtccg ggctgccggg gcgcgtgaca ctgcggtcgc agcgagaggc
    24601 cggtccggcg ccgacctacc gggagtactc cgatgaggtc gccgaagccg atgcggtggc
    24661 ccgggccatc tcgcggctcc gcgatgacgg gacggcgttg cgcgatatcg ccgtactgtt
    24721 ccggaccaat gcgcagtcgg agaacttcga gcaggcgctg gccgagcgga agatcccgac
    24781 ggtgctgaag ggcgccgagc ggttcttcga gcgggccgag atccggcagg ccgccgtact
    24841 gctgcgtggt caggcgaagg ccggtgacgt gtccgacgat ctggtctcta cggtgaccgg
    24901 agtgctgggc ggagccgggt ggacgccgga gccgccgacc gggaccggcg ccgtacggga
    24961 tcggtgggag tcgctgagcg cgctggtgac gatgacctcc gacttcgctg ctgctcatcc
    25021 atcggccggg ctggtcgatt tgatggcgga gctggatcgg cgggcgtcga ttcagcatgc
    25081 gccgctggcg gagggcgtca cgctggcgac gctgcacgcg gccaaggggc tggagtggga
    25141 ctgtgtcttc attgtggggg cgcacgaggg gacgctgccg atcagctacg cccagacgcc
    25201 ggcgcaggtg gaggaggagc ggcggctgtt ctatgtcggc gtgacgcggg caaaagagca
    25261 actgtttgtt agctggtcga tgtcgcgctc gccgggtggc cgcgggacgc gtgggccgac
    25321 ccggttcctg gatccgatcg gtgtccgtac gtcgcgcacc tcgtcaactg agtgggagcg
    25381 gccgcccgcg gaggcgcgcg cgccccggtc tggcaagccc atccccaagt gccgggtctg
    25441 cggccgcggc ctgctcgacc ccggcgcccg caaactcggc cgctgcgagg actgcccgtc
    25501 ctccatcgac caggacctgt acgacgctct gatcgcctgg cgcaccgaac aagcttcggc
    25561 tgagcgcatg ccggcgttcg tcatcctcac cgacgccacc ctgaccgcga tcgctgagac
    25621 ccggccgacc gacgagcagg cgctgcgccg gatcccgggg atcggccacg ccaagctgac
    25681 caagtacggc gagctcatcc tcaacctctg cacccgctga ttccccaacg ggcagtcacc
    25741 ggataaaggt gttgccatac ctgggccgcg aggcgcatgg tggaggacgt gccgcattct
    25801 gccgacggca gacgtggcat ataggtgaca gaggcaacga tcccggagcg tgcggatggc
    25861 gtcccggagc gtgctggaag cctgtcgtgg cagctggttc cggccaccgc ggcggcaact
    25921 tccggccaac ttcgcgaact ggcgataaat agtttgcggg ctccggcgag gacggcgtac
    25981 tgttctttct gcggtcgaag cctggccgaa aacttcaaac caccatagcg atcgagctaa
    26041 ccgcccgctt cgccacaacg agaggaggtg ccctggaatg aacatcaaca cggtcaagaa
    26101 gccgttcagc gacgttgtcg cgctgccgtg cgccccgatt cagggtgcct cgccgcgtct
    26161 gcacgtcgcg accgttgtgc tcatggcctc cggcgctgcc cagttcaagg gcggagctgt
    26221 cggcgatgtg aagtacggcg gttcgggttc tcgagcatgg agtccaccgg tctgacaagc
    26281 gtcagcgccg gcacctccag gccgcggaac ccgaaagggt cccgcggccc ttttgtttgt
    26341 ccctgatttt ggcggtcatc aaccgttgac cgtcaccgac gacaagagat cagcaccaaa
    26401 gtcacttggg aggtgaccgg aatgagcgtg agcttcctcg atgtcttcac cgaggtggcc
    26461 tcgtcgcagg acctgccctg tcggtcctac gcgccagaac tcttcttcgc cgaatcgccg
    26521 gcggacgtcg agtatgcaaa gtctctttgc accacctgcc cgctgaaggc cgagtgcctg
    26581 gccggagcgc tcgagcgttc cgagccgtgg ggagtgtggg gcggcgaact gttcgtccag
    26641 ggtgtggtgg ttccgcgcaa gcggccccgt gggcgtcccc gtaagagcga caccgtgacc
    26701 gcagcctgac gatccagatc cgaatcgaga cttcgaacca tgaccaacca gacttcgcac
    26761 aggagaattg agatgcattt acttcacgaa gatctcgccc gtgctcattg tcgggccaaa
    26821 ctgcacgacg ccgagcagaa ccggcgcttc cgcctcgctc agcagatcga gcgggcgcag
    26881 aagcaggccg agcgggccgg ccggcgagct gagagggcca gcgcacgcgc gcgcctcgca
    26941 ctcgcccgcc tcgtctgaaa cacccaggcc tcaccggctc cggccggagg cctacagcct
    27001 gaccagctga aacaccgagg ggcggcaccc accgagggtg ccgcccctcg ccacgtcgtc
    27061 gggccctcag atggtttggg ccaggagggt ctgctggagg cccaggaggg tgatgccgga
    27121 gaggatttcg tgccgggtga tcatgccggg gatgtccggg agcgggatcc actcgatccg
    27181 gtccgactcg ttgcgttcga ccggtgggcc gacgtacgac gcggacgtcg tacggaagac
    27241 gtggtgggtc gagtccatga tcccggcgcc gggctgggag cggatgagct ccgtcagcgg
    27301 ccccgggcgc cagcccgtct cctcctcgac ctcccgtgcg gcggcagcga ccggagcctc
    27361 gccgggctcg acgatgccca tcggcagctc ccagccccag gtgtcggtca ggaagcggtg
    27421 ccgccacatc aggagcacgc tggagtcgac catgacgacc gccgccgcca cgtcgctcag
    27481 ccggatcgcg tggtagtcga cccgctcacc gtcgggctgt tcgacgtcca gccgccgtac
    27541 gctcagccac ggacttgacc aggcctcttc ctctccgtgg atgtgccagc gcatgctgag
    27601 gagcataggc cggacgaggg ggtaccggcc ggggaggctt cgagaggtgg agctggtcga
    27661 cgtcggtggg cggcggatcg cctaccaccg ggccggcgct ggggaaccgg ctgtgctgct
    27721 ccacgggggt tggagcgacg gccgggcgtg gcagcggcag ctggccgggc tggctgggtt
    27781 cgatctgatc gcctgggatg caccgggctg cggcggctcg gcggaccccg cggccaggat
    27841 gaccctgtcc gactacgccg acgtgctggc cgaggtggtc acagctctgg gcgtcgagcg
    27901 ggcgcatctg tgcggcctgt cctggggcgg tggcctggcc atcgctgtgt ggcaacgcca
    27961 ccccgagctg gtgcgctcgc tggtcctggc aggggcgtac gccggctgga agggctccct
    28021 gccgccggac gaggtggagg cccgggtacg gcggatccgc gccgaagctg agcggccgcc
    28081 ggcagagtgg atggacggct acctgcccag cttcttcgcc ggcccggtgc cggccgaggc
    28141 gacccagctg atccgcacga tgatggcgga gagccgtccg gccggctcgc tgatgatgtt
    28201 gaccgcgttc gccgaggccg acctcagcgc ggtgctgccc acgatcgacg tacccacgct
    28261 gttgctgtgg ggtgagtgcg accagcgcgc accggtcggc acggtcgcgg cgacgctctg
    28321 ggcgaggatt cccggtgcgg aactcgtggt gctgcccgga gtgggtcact acaacaacct
    28381 cgaggcaccg gaagagttca acgccgaggt acgacgtttc ctcggcgaca gcaggagata
    28441 ggccggcagg ggtaccggcg tgggggaggt gcacactgat gcgcatggtg agagcgacct
    28501 gtgggttgtg tggtcagcag gcggagaccg aagaagcgcc gctgacctgg gtgacgtccg
    28561 tggagaatgg ccggaagctg ctgtactgcg accgctgcgc ccgggagaac gtccgcaaca
    28621 tcgaggggaa gctggactcc gtctactggt agagaattct gagccggatg tcgatccggc
    28681 ggtgatccgg ccgacgcagg agtaaaggca ctccagcgga aggacccgga tcatgacact
    28741 caccgagagc gcggacgtgg cgaccagtcg ccgccagtgg atcgggctgg gcgtgctgtg
    28801 cctcgccacg ctactggtgt cactggacct gttcgtgatg ctgctggccg ttccggcggt
    28861 caccgaggcc ctcggcgcga ccggtagcca gcagctgtgg atcctggacg tctacgggtt
    28921 catggtcgcc ggactgatga tcaccatggg caacctgggt gaccgtctgg gccggcgtcg
    28981 gctgttgctg gtggccgctg ctgtcttcgg tgcggcgtcg atcgtggcgg cgtactcggt
    29041 cagtccaggc atgctgattg gtgcccgggc cgtgcttggg gtcgcgggtg cggcgatcgc
    29101 gccgtgcacg ctgtcgctga tctccaccct cttcccggac acccggcagc gtgccaaggc
    29161 actcggcgtc tgggcgggct gcttcactgt cggcgccgtg gtcggtccaa tcacgggagg
    29221 cgtcctgctg gagcacttct ggtggggctc ggcattcctg atcggcgtac cggcgatggc
    29281 tgtgctgctg gcggtggggc cattcctgct gccggagtac cgcgacgaga aggcaggccg
    29341 gatcgacgta ccgagtgtgg tgctgtcgct ggctgcgatc ctgccggcca tccacgggct
    29401 gaagcagctg gcctcacacg gtgccagtcc tcaggcgttc gccgctctgg tcgggggcgt
    29461 tgccttcggt tggatcttcg tacggcgtca gcgtcgcctg gccgacccgc tggtcgacgt
    29521 acggctcttc actcgccgga cgttcagcgt gacgctcggc agcatgctgt ccttctcgat
    29581 gctgtccggt ggggtgatgg tgttcgtcgc gcagtacttc cagctggtgc ggggcatgac
    29641 gccgctggcc accggcatcg cactcgtgcc tggcatgatc accaccaccg tggcctttca
    29701 ggtggcgccg cggctggccc atcgggtccg tcccggcgta ctgatcccgg ctggcatcgc
//
