LOCUS       NZ_SLWR01000001        21071 bp    DNA     linear   CON 05-APR-2024
DEFINITION  Kribbella antiqua strain VKM Ac-2541 Ga0310564_101, whole genome
            shotgun sequence.
ACCESSION   NZ_SLWR01000001
VERSION     NZ_SLWR01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Kribbella antiqua
  ORGANISM  Kribbella antiqua
            Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
            Kribbellaceae; Kribbella.
REFERENCE   1  (bases 1 to 1298168)
  AUTHORS   Whitman,W.B., Woyke,T., Klenk,H.P., Zhou,Y., Lilburn,T.G.,
            Beck,B.J., De Vos,P., Vandamme,P., Eisen,J.A., Garrity,G.,
            Hugenholtz,P. and Kyrpides,N.C.
  TITLE     Genomic Encyclopedia of Bacterial and Archaeal Type Strains, Phase
            III: the genomes of soil and plant-associated and newly described
            type strains
  JOURNAL   Stand Genomic Sci 10, 26 (2015)
   PUBMED   26203337
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1298168)
  AUTHORS   Whitman,W., Huntemann,M., Clum,A., Pillay,M., Palaniappan,K.,
            Varghese,N., Mikhailova,N., Stamatis,D., Reddy,T., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Prokaryotic Super Group, DOE Joint Genome
            Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.12.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 185.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004345665.1-RS_2024_04_05
            Annotation Date                   :: 04/05/2024 04:15:41
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,825
            CDSs (total)                      :: 7,760
            Genes (coding)                    :: 7,713
            CDSs (with protein)               :: 7,713
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 58
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 7 of 47
            Pseudo Genes (incomplete)         :: 41 of 47
            Pseudo Genes (internal stop)      :: 3 of 47
            Pseudo Genes (multiple problems)  :: 4 of 47
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:43:35
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 937573
            Orig. end                         :: 958644
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            SLWR01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21071
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="2"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21071
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21071
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11071](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11071
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    227..239
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.27"
                     /tool="antismash"
     gene            complement(236..613)
                     /locus_tag="EV646_RS04520"
                     /old_locus_tag="EV646_101919"
     CDS             complement(236..613)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020390322.1"
                     /locus_tag="EV646_RS04520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_101919"
                     /product="DUF6504 family protein"
                     /protein_id="WP_132144123.1"
                     /transl_table=11
                     /translation="MWEFDEAVEVRTDVENGVDTPAQFLWRGRLWRVCSVQAHWTETAA
                     WWERGTIGRGLSTAVAPVGVDAAAVGGSPAAVGVLDADWGPRRAVYRVEAGCGRQGRRE
                     LFDLAHDPDSGRWQLERVMDR"
     misc_feature    complement(621..639)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.59"
                     /tool="antismash"
     misc_feature    823..838
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: medium, score: 25.27"
                     /tool="antismash"
     misc_feature    complement(824..837)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 21.07"
                     /tool="antismash"
     gene            975..1541
                     /locus_tag="EV646_RS04525"
                     /old_locus_tag="EV646_101920"
     CDS             975..1541
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012920487.1"
                     /locus_tag="EV646_RS04525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_101920"
                     /product="DM13 domain-containing protein"
                     /protein_id="WP_132144125.1"
                     /transl_table=11
                     /translation="MRKRWRAALIAAAAGAVVVLAVALPLFQPWRLFTDKVVDEALPSA
                     VPISTNSSSTTPPTISGAPSSHRPTAPEILLTGKLITHEHETSGTVAVLRLPDGSRILR
                     LENLDTSDGPDLKVWLSDAPVIVGKNGWHVFDDGRYRSLGGLKGNHGSQNYPIPKEVRL
                     DDFQSVAIWCDRFNVSFGAAELKST"
     gene            1564..2037
                     /locus_tag="EV646_RS04530"
                     /old_locus_tag="EV646_101921"
     CDS             1564..2037
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020390324.1"
                     /locus_tag="EV646_RS04530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_101921"
                     /product="YbaK/EbsC family protein"
                     /protein_id="WP_132144127.1"
                     /transl_table=11
                     /translation="MSNHHPNVQRVADALQAAGSTGEIVILDDAVPTAAAAAAELGCEV
                     GAIANSLIFDGDGAPVLILTSGAHRVDTAKVAAELGISKLRRATPEFVKEHTGQSIGGV
                     APVGHPHPVPTYVDTALEQYDVIWAAAGIPHSVFPTTYAELLKLTNGTPTTVN"
     misc_feature    complement(1595..1609)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.35"
                     /tool="antismash"
     gene            complement(2128..4044)
                     /locus_tag="EV646_RS04535"
                     /old_locus_tag="EV646_101922"
     CDS             complement(2128..4044)
                     /EC_number="3.5.1.28"
                     /GO_function="GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA]"
                     /GO_process="GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012920484.1"
                     /locus_tag="EV646_RS04535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_101922"
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_132144129.1"
                     /transl_table=11
                     /translation="MRRRPKILAALAAVALPMAVSGVSSGGPPAVAATPGPSATVASAF
                     SDAAAKYGVPESVLLAVSYAESRWDDHQGASSTDGGYGPMHLTAVDPTTVVDLSGERKI
                     AKASSLRTLYKASDLTGLDPVALRNDPTANIAGGAALLASYQRSLGLPAGAETSPASWY
                     GAVASYAEASDRVGAAEFADDVYSIMAQGAARTTNTGQQVVMPAVAVTPDKTQVSKLAL
                     PAGVKASSSGVECPPTLGCEWLPAPYEEFGAGDYGNHDLANRPKTGKIDYIIIHDTEGT
                     WPGVLNLVQDPTYVSWQYTMRSSDGHIWQHVKANDVAWHAGNWYVNMHSIGIEHEGFAA
                     TGATWYTESLYRNSAKLVRYLAAKNDIPLDRAHIIGHDQVPGTIPSTVRGMHWDPGPYW
                     DWEHYFDLLGAPIYGHSVFPVRKGSIVTIKPGFSDNVQVITNCTGAGTTCTPQGTNFVY
                     LRQAPDDAAPLVKDLGLHPDGTDSTTVVSDIGARAAAGSQYVVADVQGDWVGVWYLGAL
                     AWFKSPASAPDAFAKPGLVVKLKADKTSAPVYGRAYPEQSAYPAGIPYQTVTPLQYTIG
                     DGQAYPVGDASIETDYYRAVTFATEPPADHVQVLGTDRYYQIWFGHRMAYVRAADVDLK
                     PAF"
     gene            4191..4802
                     /locus_tag="EV646_RS04540"
                     /old_locus_tag="EV646_101923"
     CDS             4191..4802
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020390327.1"
                     /locus_tag="EV646_RS04540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_101923"
                     /product="DUF4126 domain-containing protein"
                     /protein_id="WP_132144131.1"
                     /transl_table=11
                     /translation="MEALPLAFTTGWASGINAYACVLILGLLGRFAGADDVPTALTSNG
                     VLIAAGVLFAFEFVADKIPYVDSAWDAISTVIRPTVGAIVAALLSGEASTLNQAVIATI
                     GGVVALLSHAVKSSLRLAINTSPEPVTNIAASSGEDIAVAGVVSLAAFHPEVALIIAAV
                     LLLLGLIGVYVAFRFIRRGYQRFKAWREKRTGPATGSSAV"
     gene            4802..6109
                     /locus_tag="EV646_RS04545"
                     /old_locus_tag="EV646_101924"
     CDS             4802..6109
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020390328.1"
                     /locus_tag="EV646_RS04545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_101924"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_132144133.1"
                     /sec_met_domain="DAO (E-value: 7.4e-10, bitscore: 35.1,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARVVVVGAGLAGLASAVRLAKLGHQVTICERDGRLGGVLGRVEA
                     DGFSWDAGAASTTLPAALRDLFRKSGRPIESLVQLEPVTEPRRHMFGDGSVLDLPISDR
                     GAQLEAWTDLASDTVAKQWTDLVDAYGETWQVLRKTSLEPPLQDKLPLSAIRALKPWQS
                     LERVAQRQLDDERARAVLRYFAAQGGSEAKLTPGYVGVWSYLERTFGRWTIEGGFGVLA
                     DALAQRASERKVDVRTGAEVVAVTTTQGAVTGVRLADGAELPADIVVSDIDPRDLFGQL
                     VDDPAAKKVRKRALSTHQAQAAYVVHLGLREPVPVLPFETVLHGTPTVVVRTGGQAPAG
                     HQAWSVLVHGYPTDDVLDLLVARGLHVRDKVVSRQTSQSWWAGVAWEGYRTARRRAANV
                     SPVKGLYCVGAGAHPGSGVPATTLGAAIVADAIGKA"
     gene            6202..8406
                     /locus_tag="EV646_RS04550"
                     /old_locus_tag="EV646_101925"
     CDS             6202..8406
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020390329.1"
                     /locus_tag="EV646_RS04550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_101925"
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="WP_132144135.1"
                     /transl_table=11
                     /translation="MDQSPKSADHENVERAELAAEQQHIDRVYDRVAEAARSASRIAVE
                     GHQRGQAQNVGRVREEEQTGLYERDVLVFAAARRIAELDAEHEGLVFGRLDSDHGDDTE
                     AAASAADLEKLYVGRIGVRDAEYEPLVIDWRAPAAEPFYRATSTDRLNVVRRRVLRNKG
                     PRIVGLEDDLLAPERAPEDLPVMGEGALMASLSRARGHTMRDIVATIQAEQDKAIRAPA
                     RGVTVIGGGPGTGKTVVALHRAAYLLYSDRRRFERGGVLVVGPSAAFMAYIERVLPSLG
                     ENTVSLKAVGELVDGVKATAVDEADVAAIKGSLRMRGVLSRAARDRVPTAPSTLRIFVG
                     GATVELDANQLDNVRRNALRRTARNRAAAEARKGLVAALWQRFPDDLRNGVYGDREAFG
                     DQVTETPAFRTFFSQWWPVLTPESVLRWLGDPRRLQRWARNDLTPTEIDALANAIRSTD
                     EFTIADVALLDELSTLLGRAPVAETKDEEFDWLEGLSDGVNEVLTTSERRARAVAAREA
                     EEPEEYAHVLVDEAQDLSPMQWRMVTRRGPQASWTIVGDPAQSSWPDPDEARAAMDSML
                     SHLQRHSFRLSTNYRNSAEIYQFAGEVIRRTLPDADLPDAVRRTGVEPEHRVFDDGKVS
                     EAAGDAAAELLQLVEGTVGVIVPPKLRPGIDAVLGELGDPRVVAVSPLESKGLEYDAVV
                     VVEPDRIVSDTLGGVRALYVVLTRATQRLVTVNSTTHWLP"
     gene            complement(8422..8952)
                     /locus_tag="EV646_RS04555"
                     /old_locus_tag="EV646_101926"
     CDS             complement(8422..8952)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012920480.1"
                     /locus_tag="EV646_RS04555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_101926"
                     /product="histidine phosphatase family protein"
                     /protein_id="WP_132144137.1"
                     /transl_table=11
                     /translation="MADPSDLLIDRTLVLLRHSKAVQDESMPDFERPLADRGRADAAAA
                     GRYLVAQGIDADLVLCSPSQRTRETWRFAAEAGAAATDVWYDRRIYNADADELLDVIHE
                     APTEARTVILVGHGPGVPWLADELALDGTSPERVELSQKYPTSGLAVLHLSCRWSDLGP
                     DDADLISFVVPRG"
     gene            complement(9026..9943)
                     /gene="metF"
                     /locus_tag="EV646_RS04560"
                     /old_locus_tag="EV646_101927"
     CDS             complement(9026..9943)
                     /EC_number="1.5.1.20"
                     /GO_function="GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA]"
                     /GO_process="GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="metF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012920479.1"
                     /locus_tag="EV646_RS04560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_101927"
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="WP_132144139.1"
                     /transl_table=11
                     /translation="MAHGLPSTLSGGTPTIRDLLATGGRSFSFEFFPPKTPEAEEVLWR
                     SIREIEQLRPTFVSITYGAGGTTRDGTIRVTERVAQDTSLTPLGHLTCVAHSRDELRSV
                     IGAYAGAGVRNMLALRGDPPGGPNQPWVAHPDGLNHAVELVELIRSLGDFCVGVAAFPD
                     KHPEAASLEADAQVLAAKAAAGADYAITQMFFGADDYFRLVERAGQLGCDIPVLPGIMP
                     VTNIKQIQRMAELTGMALPAAVTDRLLAVEDDPGAVRAVGIEIATELCERLLAGGAPGI
                     HFITLNRSTATRQVYLNLQSAVVS"
     gene            10001..11071
                     /locus_tag="EV646_RS04565"
                     /old_locus_tag="EV646_101928"
     CDS             10001..11071
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020390332.1"
                     /locus_tag="EV646_RS04565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_101928"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_132144141.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.1e-51, bitscore:
                     171.8, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYGDVDIPAEVQRALTGFLDLQQQRLEAIGPELAEQVQAARDATS
                     GGKRLRPSFCYWGFRAAGGDPAQPILKAAASLEMLHVSALVHDDVMDSSDVRRGAPAAH
                     RRFEALQRARSQTSGVGGDAERFGIGAAILLGDLCLIWADEMLHTSGFDAAALARAARF
                     FDAVRVEVTAGQYLDLVAQASGESDMDQALRVLRYKSATYTVERPLHVGAALGGGDQRL
                     IEALSAYGLPLGEAFQLRDDLLGVFGDPALTGKPAGDDLREGKRTVLIAYAVDHASEVQ
                     LAEFDRLFGRPDLDDDEIQLLREILQDSRAVQACEDLITDRTEDALAALDRAPLADGTA
                     RKALADLAIAATSRQL"
     gene            complement(11068..11487)
                     /locus_tag="EV646_RS04570"
                     /old_locus_tag="EV646_101929"
     CDS             complement(11068..11487)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020580089.1"
                     /locus_tag="EV646_RS04570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_101929"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_132144143.1"
                     /transl_table=11
                     /translation="MPQELYSVEQVANRLGLHVRTIRNYVRDGRLKAVRIGKQYRIARE
                     DLEAFTGTSAAALEVDETARNVEASSIVHIDAIDRAGADRISTHVIGSLNQSGVGRLRV
                     ETVYDEDRAVLKVIILGDLAPTAELLRLINLMTSP"
     gene            11564..11914
                     /locus_tag="EV646_RS04575"
                     /old_locus_tag="EV646_101930"
     CDS             11564..11914
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025161.4"
                     /locus_tag="EV646_RS04575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_101930"
                     /product="DUF4180 domain-containing protein"
                     /protein_id="WP_132144145.1"
                     /transl_table=11
                     /translation="MNVEGVRVYVSDARVQDDGDAVQLIADAHYGHQAEWVAVDAEQLG
                     DDFFELRTGRAGAIAQKFVNYRMGLAVVGDIAEKLAGSKPLRDWVRESNRGRSLWFVTD
                     LDALAERLQDRQ"
     gene            complement(11897..12331)
                     /locus_tag="EV646_RS04580"
                     /old_locus_tag="EV646_101931"
     CDS             complement(11897..12331)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020390334.1"
                     /locus_tag="EV646_RS04580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_101931"
                     /product="barstar family protein"
                     /protein_id="WP_132144147.1"
                     /transl_table=11
                     /translation="MTDLPTLLTEGLRPGVYRWQSDLTPDDVRRDVADAGWDFVLLDTT
                     EIHDKTGFLDLCATAFDLPRWFGRNWDALADSLSDRSTGEPEIVLWEGLHHLLDHDHDT
                     VDVALQILAEDTTNSGQLRVLIRERSEADTPDLLSSLPVL"
     gene            complement(12324..12749)
                     /locus_tag="EV646_RS04585"
                     /old_locus_tag="EV646_101932"
     CDS             complement(12324..12749)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012920472.1"
                     /locus_tag="EV646_RS04585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_101932"
                     /product="ribonuclease"
                     /protein_id="WP_199236776.1"
                     /transl_table=11
                     /translation="MINNPKAARIIAAVVIAMLVITLAASLFGCSAAKPNSTDPESGLT
                     IVAVADLPSEAQQTLKLIDQGGPFPYSRDGVVFGNFEKILPKQDRGYYHEYTVKTPGES
                     NRGARRIVTGKNGERYYTDDHYKSFRRIAADGGATDD"
     gene            complement(12746..13393)
                     /gene="thiE"
                     /locus_tag="EV646_RS04590"
                     /old_locus_tag="EV646_101933"
     CDS             complement(12746..13393)
                     /EC_number="2.5.1.3"
                     /GO_function="GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1280: thiamine-phosphate pyrophosphorylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012920471.1"
                     /locus_tag="EV646_RS04590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_101933"
                     /product="thiamine phosphate synthase"
                     /protein_id="WP_132144148.1"
                     /transl_table=11
                     /translation="MTEHTEQLEDARLYLCTDAREKQGDLEQLLDAALGGGVDIVQLRQ
                     KEMEAADELAALEVFADACKRHGKLLAVNDRADIAFVAGADVLHLGQRDLPVHAARAIT
                     GPMPIIGRSTHTFSQVNAAVTEQGSDYFCVGPTWETPTKPGRQAAGLELVSYAASRPQS
                     KPWFAIGGIDLERLDQVVEAGATRVVVVRAITEADDPAAAAAEFSRRLRGAG"
     gene            13436..14584
                     /gene="thiO"
                     /locus_tag="EV646_RS04595"
                     /old_locus_tag="EV646_101934"
     CDS             13436..14584
                     /EC_number="1.4.3.19"
                     /GO_function="GO:0016647 - oxidoreductase activity, acting
                     on the CH-NH group of donors, oxygen as acceptor [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="thiO"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012920470.1"
                     /locus_tag="EV646_RS04595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_101934"
                     /product="glycine oxidase ThiO"
                     /protein_id="WP_132144150.1"
                     /sec_met_domain="DAO (E-value: 2.8e-69, bitscore: 230.5,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPEHTSDVVVVGAGLIGLSIAWRLAADGIQVTVCDPTPGTQTSAV
                     AAGMLAPVTEVEYGEDDLLALNLASVAAWPSFAAELEELTGVPAGLHQTGTLSVAYDVD
                     DAAALRRLADYQRRLGLEVEVLSGRDARKREPLLATGVSGGVWVPGDHSVDNRQAVTAL
                     LRAVELSKVTLIRQRVSRILTSGTTAVGVQLENGDTVRAAHVVGAAGPWSGQLEGVPQE
                     LRPPVRPVKGEVLRLRVPEAYRPALQHTVRATARGFSVYLVPRPGGELVVGATSSELGY
                     DTRVLAGGVFTLLRDARTVLPITDELELVESIAGLRPATPDNAPILGPSGLEGLLWATG
                     HYRNGVLLTPITARIIADTIRTGVVPELGVPFLGSRFAHSTL"
     misc_feature    14638..14653
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 18.36"
                     /tool="antismash"
     misc_feature    14643..14661
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.42"
                     /tool="antismash"
     misc_feature    14646..14663
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 17.08"
                     /tool="antismash"
     gene            14751..15728
                     /locus_tag="EV646_RS04600"
                     /old_locus_tag="EV646_101935"
     CDS             14751..15728
                     /EC_number="4.2.2.n1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020390340.1"
                     /locus_tag="EV646_RS04600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_101935"
                     /product="lytic transglycosylase domain-containing protein"
                     /protein_id="WP_132144152.1"
                     /transl_table=11
                     /translation="MDDACTSSRRRTVVRVLTGLAVPVLTAAVITAGSPGFGQYKVKNG
                     DTLSRIATQYGTTVRNLVALNNLPGNGNTIYAGETLKVPGGKQTTKRSQLGRVTYIVKK
                     GDTISKIAKRFKCSQANLLAANGLRATDHIYAGKPLQVPVKLHPKPKPKPKAPAKKNNS
                     FAGRTYPDHVVAKADQNRAILKSRKLPTRAQMRNLIIATSKHYGVDPELALAVSWQESG
                     WKQRVVSPANAVGAMQVIPSTGRFASSVVGRDLDLLKPRDNVTAGVVLLDRLTSAAELQ
                     TAVAGYYQGLGGVKRNGMYPDTKLYVKNILRIKAQLERGWSPLK"
     gene            15825..17771
                     /gene="pknB"
                     /locus_tag="EV646_RS04605"
                     /old_locus_tag="EV646_101936"
     CDS             15825..17771
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pknB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020390341.1"
                     /locus_tag="EV646_RS04605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_101936"
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="WP_132144154.1"
                     /sec_met_domain="Pkinase (E-value: 3e-51, bitscore: 170.4,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="APH (E-value: 9.3e-08, bitscore: 28.5,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDDVDTQVSDRLVGRVLDGRYRVGARVAKGGMATVYKALDMRLD
                     RVVALKVMHDGLGDDAQFARRFVAEARAAARLSHPNVVAVFDQGDDNGTLFLAMEYVPG
                     RTLRDVIRQQAPLSPARALDLLAPILSALSAAHDAGIVHRDIKPENVLISDNGAVKVAD
                     FGLARAVSATGNTATQGLLMGTVSYLAPELVTDGSADARSDVYSSGILLYEMLTGNKPH
                     SGDTPIQVAYAHVHADVPAPSLEQPTIPPYVDALVQRATARDRDLRPADARVLSRQVHR
                     VRSALEEGLPDDPELTGDLTVPIQQIRQDSGYDDGYTRGDPEDAVLRHDTIVVPVEHGR
                     PTGAPATRVQAPPQRRGRGLVALILVLAAAIGVGTAAWYYGIHRYTTTPSLVKMVPADA
                     TAEAEKAGLRTNLANQDFSEDVPKGQVMATDPSAGDRIRKNGEINLTVSKGPERYRVPQ
                     LAGLELEAAKRALDSIKLITGQINEQYSETVPAGRVIAFSPKFDAVVKPGTAVNFAVSK
                     GKKPIAVPDVTGKTYRQAREALRNLGFVVGRTDQYDEKIAEGKVISQTPNTGTLFAKDK
                     VQLVVSKGPALREVPNVKRKTLDEAQQILTEAGFKVRVEKAPFNLGLNIVAAQNPGSGK
                     MAQPGTTVVVTVL"
     gene            17811..18692
                     /locus_tag="EV646_RS04610"
                     /old_locus_tag="EV646_101937"
     CDS             17811..18692
                     /GO_function="GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017933887.1"
                     /locus_tag="EV646_RS04610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_101937"
                     /product="DMT family transporter"
                     /protein_id="WP_132144156.1"
                     /transl_table=11
                     /translation="MNHPRLAVVALLAVAAAWGSTFFLTKDLLTRMDVADYLALRFLIA
                     SVALVLVHPPAIARLSRLDRGRAVALGITYGIAQLLQTEGLRHTAASVSGFVTGMYVVF
                     TPLLAAVILRHKIGRWAWVAVILATVGLGVLSLRGVSMGPGELLTLASAGLYALHIIGL
                     GAWSTSANAFGLSSLQMITITAVCAIGAIPGGFSIPGTGGDWVSVFYMALVSGALALIV
                     QTWAQAHLTPTRAAIAMTMEPVFASAFAVLFGSESVTWRMLVGGALVLSAMYLVELAPR
                     RKFEAEVQHLAQ"
     gene            18705..19874
                     /locus_tag="EV646_RS04615"
                     /old_locus_tag="EV646_101938"
     CDS             18705..19874
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020390343.1"
                     /locus_tag="EV646_RS04615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_101938"
                     /product="glucoamylase"
                     /protein_id="WP_132144158.1"
                     /transl_table=11
                     /translation="MRDDSARRVRRFPAVVIAVLLAVLAAGTANNLARNPQPLLVAPGN
                     VSRGDDLAGQAVLDLDALTLPNGATLAGPDGPWRFVWPRDASFVAAARCSLGQFDEAGR
                     VLDFLNKIRPSSGRWEARYSSDGLLVRDGREPQLDGSGWVLWATWFCHAGSRYWEMVRE
                     SADQIVAELGPNGLPARSPDYWERPERVVTLGTIAPLLTGLRAAVAIAHDLDRPAEAAR
                     WQDALNKLSSATDRSFGPDFPRTPARAVSFLEPGLEPIGLGGGADAIVTVLGPPFAPPR
                     DDVDHAIDNARAALTQPNGGVTPGEDWRTDGVSWTPQTALFALSAAARGDRATASSLLT
                     WLNHYRTSTGALPEKVNRDLQPAGEAPLAWTSALVILTHAALQTPLPIP"
     gene            complement(19939..21006)
                     /locus_tag="EV646_RS04620"
                     /old_locus_tag="EV646_101939"
     CDS             complement(19939..21006)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012920463.1"
                     /locus_tag="EV646_RS04620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV646_101939"
                     /product="glycoside hydrolase family 172 protein"
                     /protein_id="WP_132144160.1"
                     /transl_table=11
                     /translation="MTLGKLCGISAILDVETRSISAENPTGEPGQGGRRTEGTGANAAR
                     DLGQGWKVSPSIEIGAGETAVLADIAGSGCITHIWLTTHVDHWRRLVLRSYWDGDEAPA
                     IETPVGDFFCSGWGKFAQVNSLPVAVNPNGGFNSYWEMPFQSQAKLTLENTHDEPVIVY
                     FQVDYWLGAVPEQSAYLHAQWRRSNPLQAKTVHTLLDGVEGPGHYVGTYVAWGVNSSGW
                     WGEGEVKFYVDGDDEFPTICGTGTEDYFGGAWNFDVPGDGYTEFSTPYLGMPQVIRPDG
                     LYASQQRFGMYRFHLPDPIRFREKLRVDVQALGWRSGGRYLPLQDDIASTAFFYSAKTS
                     TTRPDAPSNESMEIC"
     misc_feature    complement(21039..21050)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.1"
                     /tool="antismash"
ORIGIN
        1 gcgacctcgg cgagcaggac ccaggcgttg cgctgcaccc ggcggcgcgg gcccgagcga
       61 accgggcgag cccgaacggc gaggaccgcc gccgcgaccc ggagggctgc gatgtgagcg
      121 ctcgagtaac ggatcaggtg atcgctcgtc tccacggctt ccgcgagcgc ggcccgcgcc
      181 cgggagagct cccggctggc cgctccggca gccgccggcg acaccggtga aactgtcatc
      241 ggtccatcac cctttccagt tgccagcgac cggagtccgg gtcgtgcgcg agatcgaaca
      301 gctcgcgccg cccctgccgg ccgcaccccg cctccacccg gtacaccgcg cgtcgtgggc
      361 cccaatccgc atccagtacg ccgaccgccg cgggactacc gccgacagcc gcggcgtcca
      421 cgccgactgg agcaacggcg gtgctcaggc cgcggccgat ggtgccgcgt tcccaccagg
      481 cggcggtttc ggtccagtgg gcctggacgg agcagacacg ccagaggcgt ccgcgccaca
      541 ggaactgggc cggggtgtcg acgccgttct cgacgtccgt gcgtacctcg acggcctcgt
      601 cgaactccca catgctccat cgcctcctgt gtacgaactg cccctgatcg acggcccggt
      661 cggcggtccg gcgggtggac acgaggtggg ggtcgagttc cacctcggtg cccggcccgc
      721 cggaaccacc ggtttccgat gcggccgcaa ctccacaccg gagccgtcca gctgtccgga
      781 tcacccctgg ccggcctccc gacgaagccg ggccggaggt aatcgaacat ctgttcgaac
      841 actcgaagac tatcgccgcc gggtgggaat cgtcaacggg ccgtaagccc ggcgcgtccc
      901 cacgtacgcc atccgccgcc cacactggtg tcaggacaag accggcgtgc gtcgtacagg
      961 cggaagggga agcgatgcgg aagcgttggc gggcggcact gatcgccgcg gcggctggtg
     1021 ccgtcgtggt cctggcggtc gcgttgccgc tcttccagcc gtggcggctc ttcaccgaca
     1081 aagtcgtcga cgaagcgcta cccagcgccg ttccgatctc cacgaattca tcgtcgacga
     1141 cgccaccgac aatttccgga gccccgtcaa gtcaccggcc aacggccccg gaaatcctcc
     1201 tcaccgggaa gctgatcacg cacgaacacg agacctccgg cacagtcgcc gtactgcgac
     1261 tcccggacgg ctcccgcatc ctccgcctgg agaacctcga cacctccgac ggccccgacc
     1321 tcaaggtctg gctcagcgac gccccggtga tcgtcggcaa gaacggctgg catgtgttcg
     1381 acgacggtcg ataccgcagc ctgggaggcc tgaaaggcaa tcacggcagc cagaactacc
     1441 cgatccccaa agaagtgcgc ctcgacgact tccaaagcgt cgcgatctgg tgcgaccgct
     1501 tcaacgtgtc cttcggggca gctgagctca aatccacgtg acacgccgca taagctgccg
     1561 agggtgagca atcatcatcc caacgtgcaa cgggtggccg acgcgctcca ggcggccggg
     1621 tccaccggtg agatcgtgat cctggacgac gcggtcccga ctgcggcggc cgcggccgcc
     1681 gagctgggct gcgaggtcgg cgcgatcgcg aacagcctga tcttcgacgg cgacggcgcc
     1741 ccggtactga tcctgacctc cggcgcccac cgggtcgaca ccgccaaggt cgccgccgag
     1801 ctcggcatca gcaagctgcg ccgcgccacc ccggagttcg tcaaggagca caccggccag
     1861 tcgatcggcg gcgtcgcccc ggtcggccac ccgcacccgg tcccgacgta cgtcgacacc
     1921 gccctcgagc agtacgacgt catctgggca gccgccggca tcccccactc ggtcttcccc
     1981 accacctacg ccgaactcct caaactcacc aacggcaccc cgaccaccgt caactgatca
     2041 gctcaccgac agcaacaagt acgacgaagc cgtccagcac caggctggac ggcttcgtcg
     2101 gtcgcaggca gttctagaag gccggttcta gaaggccggc ttcaggtcta cgtcggctgc
     2161 tcggacgtag gccatgcggt ggccgaacca gatctggtag tagcggtccg tgccgaggac
     2221 ctggacgtgg tcggccgggg gttcggtggc gaaggtgacg gctcggtagt agtccgtctc
     2281 gatcgacgcg tcacccaccg ggtacgcctg gccgtcgccg atcgtgtact gcagcggcgt
     2341 gacggtctgg tacgggatac ccgccgggta cgccgactgc tccgggtacg cacgcccata
     2401 caccggcgcc gacgtcttgt ccgccttgag cttcaccacc agacccggct tggcgaaggc
     2461 atccggtgcc gacgccgggc tcttgaacca cgccagcgct ccgaggtacc agaccccgac
     2521 ccaatcccct tgcacgtccg ctacgacgta ctgcgaacca gccgcagctc gtgcaccgat
     2581 gtcagagacc acagtggtgc tgtcggtgcc gtccgggtgc aggccgaggt ccttgaccag
     2641 cggagcggcg tcgtcaggcg cctgacgcag gtagacgaag ttggtgccct ggggggtgca
     2701 ggtggtgccg gcaccggtgc agttggtgat gacctggacg ttgtcgctga agcccggctt
     2761 gatcgtcacg atcgagccct tacgcaccgg gaagaccgag tggccgtaga tcggtgcacc
     2821 gagcaggtcg aagtagtgct cccagtccca gtacggtccc gggtcccagt gcatgccgcg
     2881 gaccgtgctc gggatggtgc ccggtacctg gtcgtggccg atgatgtggg cccggtcgag
     2941 cgggatgtcg ttcttggcgg ccaggtagcg caccagcttg gccgagttgc ggtagagcga
     3001 ctcggtgtac caggtcgcac cagtcgcggc gaagccctcg tgctcgatgc cgatgctgtg
     3061 catgttcacg taccagttgc cggcgtgcca ggcgacgtcg ttggccttga cgtgctgcca
     3121 gatgtgcccg tcggacgagc gcatggtgta ctgccagctc acgtacgtcg ggtcctgcac
     3181 caggttgagc acacccggcc aggtgccctc ggtgtcgtga atgatgatgt agtcgatctt
     3241 gccggtcttc ggccggttcg ccaggtcgtg gttgccgtag tcaccggcac cgaactcctc
     3301 gtacggcgcc ggcagccact cacaccccag ggtcggcggg cactccacac cagagctcga
     3361 agccttgacg ccggccggca gcgccagctt cgagacctgc gtcttgtccg gcgtgacggc
     3421 gacggccggc atcacaacct gctgcccggt gttcgtcgta cgggcggcac cctgcgccat
     3481 gatcgagtaa acgtcgtcgg cgaactccgc tgcgcccacg cggtccgaag cctccgcgta
     3541 cgacgccact gcgccgtacc aggatgcggg agacgtctcg gcaccagcag gaaggccaag
     3601 cgacctctgg tacgacgcca gcagtgcggc accaccggcg atgttcgcag tggggtcatt
     3661 gcgcagggca acaggatcga gcccggtcag gtcggacgcc ttgtacagcg tgcgcagcga
     3721 cgaggctttg gcgatcttgc gctcaccgga caggtcgacc accgtggtgg ggtcgacagc
     3781 agtgaggtgc atcgggccgt agccgccgtc cgtgctggac gcaccttgat ggtcgtccca
     3841 gcggctttcg gcgtacgaca cagccagcag cacggactcc ggtacgccgt acttcgcggc
     3901 agcatcgctg aaagccgatg cgaccgtggc ggacggccca ggggtcgccg cgacggcagg
     3961 tgggcctccg gacgacacgc cggatacggc catgggcagc gctaccgccg ccagtgcggc
     4021 gagaatcttc ggacgacgac gcatgttgtt ctcctgaacc cgacgaggcg gatgccggtc
     4081 accaagactg gcatcactct gggtcgagtc ggcgcacatg tcaacggcta accaaaactc
     4141 gccatcatcg gttcaatact gacagcagct gggaactgag gagcaggacg atggaagcgt
     4201 tgccgttggc gttcacaacg ggctgggcga gtggcatcaa cgcgtacgcc tgcgtgctga
     4261 tcctgggcct gctcggccgg ttcgccggtg ccgacgacgt acccaccgcg ttgaccagca
     4321 acggcgtgtt gatcgccgct ggtgtcctgt tcgcgttcga gttcgtcgcc gacaagatcc
     4381 cgtacgtcga ctccgcctgg gacgcgatct cgaccgtcat ccggccgacc gtcggcgcga
     4441 tcgtcgccgc cctgctgtcc ggcgaggcga gcacgctgaa ccaggccgtg atcgcgacca
     4501 tcggtggcgt cgtcgcgctg ctttcacacg cggtcaagtc cagcctccgg ctggcgatca
     4561 acacctcccc cgagccggtc accaacatcg ccgcctcgtc cggtgaggac atcgcggtcg
     4621 ccggcgtggt gtcgctggcc gcgttccacc cggaggtcgc gctcatcatc gccgcggtcc
     4681 tgctgctgct cggcctgatc ggggtgtacg tcgccttccg gttcatccgg cgcggctacc
     4741 agcggttcaa ggcgtggcgg gagaaacgga ccggccctgc gaccgggagc agtgccgtct
     4801 gatggctcgc gtagttgtcg tcggggccgg tctcgccggt ctcgccagtg ccgtccggct
     4861 ggccaagctc ggccaccagg tcaccatctg cgaacgcgac gggcgcctgg gcggcgtgct
     4921 gggccgcgtg gaggcagacg ggttcagctg ggacgcagga gcagcaagta cgacgctgcc
     4981 ggccgcgctg cgcgacctgt tccggaagag cggtcgcccg atcgagagcc tggtccagct
     5041 cgagccggtg accgaaccac gccggcacat gttcggagac ggctcggtgc tcgacctgcc
     5101 catttccgac cgcggtgcgc aactcgaagc ctggacagac ctcgccagcg acacagtggc
     5161 caagcaatgg accgatctgg tcgatgccta cggcgagacg tggcaggtac tgcgcaagac
     5221 gtcgctggag ccgccgctgc aggacaagct gccgttgagc gccatacgag cgctcaagcc
     5281 ctggcagtcg ctggagcggg tagcccagcg ccagctggac gacgagcgcg ctcgcgccgt
     5341 actgcggtac ttcgcagcgc agggcggctc ggaagccaag ctcacacccg ggtacgtcgg
     5401 cgtctggtca tacctggagc gcaccttcgg ccgctggacc atagagggcg ggttcggcgt
     5461 actcgcggac gcgttggcgc agcgggcgag cgagcggaag gtcgatgtgc gcactggtgc
     5521 cgaggtggtc gctgtcacca caacgcaggg cgctgtgacg ggtgtacggc tggctgatgg
     5581 ggctgagctc ccagcggaca tcgtggtgag cgacatcgac ccgcgtgacc tcttcgggca
     5641 gctggtggac gacccggcag ccaagaaggt gcgcaagcga gcgctgtcga cacaccaggc
     5701 ccaagcggcg tacgtcgtac atctggggct gcgggagcca gtgccggtgc tgccgttcga
     5761 gactgtcctg cacggtacgc cgacagtcgt cgtacggacg ggtggtcagg caccggctgg
     5821 gcaccaggcg tggtcggtgc tcgtgcacgg ctacccgacg gacgacgtac tggacctgct
     5881 ggtggcgcgt gggctgcacg tccgcgacaa ggtcgtgtcg cggcagacct cacagtcctg
     5941 gtgggccggg gtcgcgtggg agggctatcg cacggcccgg cgccgggcgg ccaacgtctc
     6001 gccggtgaag ggcctgtact gcgtcggtgc gggcgctcac ccgggttccg gcgtacctgc
     6061 caccacgctg ggcgccgcaa tagtggcgga tgccatcggg aaagcctgag acccgctggg
     6121 gtccaggttg ccgtcccacg taggattgat cgttcatgtg ttccatgtcg ggataggtgc
     6181 ccggcagtag agaggacctc ggtggatcaa tcccccaaat cggccgatca cgagaatgtc
     6241 gagcgggctg agctggcggc cgagcagcaa cacatcgacc gggtctacga ccgggtcgcg
     6301 gaggctgccc ggtcggcgtc ccggatcgcg gtcgaagggc accaacgcgg gcaggcgcag
     6361 aacgtcggcc gggtccgtga ggaggagcag accggtctgt acgagcggga cgtgctggtg
     6421 ttcgccgccg cccgccggat cgccgagctg gacgccgagc acgagggcct ggtcttcggc
     6481 cggctcgact ccgaccacgg cgacgacacg gaggccgcgg cgagcgcagc cgacctggag
     6541 aagctgtacg tcggccggat cggtgtccgg gacgcggagt acgaaccgct ggtgatcgac
     6601 tggcgtgccc cggccgctga gcctttctac cgcgccacct ccaccgaccg gctgaacgtc
     6661 gtacggcggc gggtgctgcg gaacaaggga ccgcggatcg tcgggctcga ggacgacctg
     6721 ctcgcgccgg agcgggcacc cgaggacctc ccggtgatgg gtgagggcgc gctgatggcg
     6781 tccctgtcgc gggcacgcgg tcacacgatg cgggacatcg tcgccaccat ccaggccgag
     6841 caggacaagg cgatccgggc gccggcccgc ggtgtcaccg tcatcggcgg tggacccggc
     6901 actggcaaga cagtggtcgc gctgcaccgc gcggcgtacc tgctctacag cgaccgccgg
     6961 cggttcgagc gcggcggcgt actggtcgtc gggccgtccg ctgccttcat ggcctacatc
     7021 gagcgcgtcc tgccgagcct tggcgagaac accgtgtcgc tgaaggcggt cggcgagctg
     7081 gtggacggcg tcaaggccac cgcggtcgac gaagccgacg tagccgcgat caagggctca
     7141 ctgcggatgc gcggcgtact gtcgcgtgct gcccgcgacc gcgtgcccac cgcccccagc
     7201 actttgcgga tcttcgtcgg cggcgccacc gtcgagctgg acgccaacca gctggacaac
     7261 gtacgacgga acgcgctgcg gcggacggca cgcaacagag cggctgccga agcccgcaag
     7321 ggtctggtcg ctgcgctgtg gcagcggttc cccgacgacc tgcgcaacgg cgtctacgga
     7381 gaccgtgaag ccttcggcga ccaggtgacc gagacacctg cgttcaggac attcttcagc
     7441 cagtggtggc cggtgctgac cccagagtcc gtactgcgct ggctcggtga cccacgccgg
     7501 ttgcagcggt gggcccgcaa cgacctgact ccgacagaga ttgatgcgct cgccaacgcg
     7561 atccgcagta cagacgagtt caccattgca gacgtagccc tgctggacga gctgagcacg
     7621 ttgctgggac gcgcaccggt cgcggagacc aaggacgaag agttcgactg gctggagggc
     7681 ctgtcggacg gggtcaacga agtgctcacc acatctgagc gccgggcccg ggctgtggct
     7741 gccagagagg ccgaggagcc ggaggagtac gcgcacgtcc tggtggacga ggcgcaggac
     7801 ctctccccca tgcagtggcg gatggtgact cggcgcggcc cgcaggcgag ctggacgatc
     7861 gtcggcgacc ccgcgcagag ctcgtggccc gacccggacg aggcccgtgc ggcgatggac
     7921 tcgatgctgt cgcacctgca gcggcactcg ttccggctgt cgaccaacta ccggaactcg
     7981 gccgagatct accagttcgc cggagaggtg atccgccgga ctctgcccga cgccgatctg
     8041 cccgacgcag tacgtcgtac tggcgtggaa ccggagcacc gagtcttcga cgacggcaag
     8101 gtctccgaag ccgccggtga cgcggccgcg gagctgctcc agctggtcga gggcacggtc
     8161 ggcgtgatcg tgccgccgaa gctacggccc gggatcgacg cggtcctcgg cgagctcggc
     8221 gacccccgcg tggtcgcggt cagccccctg gagtcgaagg gtctcgagta cgacgctgtc
     8281 gtcgtggtcg agccggaccg catcgtcagc gataccctcg gcggcgtacg agccctgtac
     8341 gtcgtcctga cccgggcaac tcagcgactg gtcaccgtca acagcaccac ccactggctg
     8401 ccttaaaagt atgtagagcc gctagccgcg agggacgacg aacgagatca ggtcggcgtc
     8461 gtccgggccg aggtcggacc agcggcagct caggtggagg acggcgaggc cggaggtcgg
     8521 gtatttctgg ctgagttcga cccgctccgg gctggtgccg tcgagggcga gctcgtcggc
     8581 gagccacggt acgccggggc cgtggccgac caggatcaca gtgcgggcct cggtcggcgc
     8641 ctcgtggatg acgtcgagga gctcatcggc gtcggcgttg tagatgcgcc ggtcgtacca
     8701 gacgtcggtc gcggccgccc cggcctcggc ggcgaaccgc caggtctcgc gggtgcgctg
     8761 cgacggtgag cacaggacca ggtccgcgtc gatgccctgg gcaacgagat agcggccggc
     8821 cgcggcggcg tcggcccggc cgcggtcggc gagcgggcgc tcgaagtcgg gcatcgactc
     8881 gtcctgcacc gccttcgagt gccggagcag gacgagcgta cggtcgatca aaaggtccga
     8941 cggatcagcc accgagtcag gatacgacgg cggaccgggt cacgggacga cggcagaccg
     9001 ggtcactgga cgacggccga ctgggtcagg agacgacggc cgactggagg ttgaggtaga
     9061 cctgacgggt cgcggtggac ctgttcaggg tgatgaagtg gatgcccggc gcgccgcccg
     9121 ccagcaggcg ctcgcacagc tcggtcgcga tctcgatgcc gaccgcccgg accgcgccgg
     9181 ggtcgtcctc gaccgcgagc agccggtcgg tgaccgcggc cggcagcgcc atcccggtca
     9241 gctccgccat ccgctggatc tgcttgatgt tggtgaccgg catgatgccc ggcagcaccg
     9301 ggatgtcgca gcccagctgg cccgcccgct cgaccagccg gaagtagtcg tccgcgccga
     9361 agaacatctg ggtgatcgcg tagtccgcac cggcggccgc cttggcggcg agcacctgcg
     9421 catcggcctc cagcgacgcc gcctccggat gcttgtccgg gaacgccgcg accccgacgc
     9481 agaagtcgcc gagcgagcgg atcagctcga ccagctcgac cgcgtggttg agcccgtcgg
     9541 ggtgcgcgac ccacggctgg ttcgggcccc ccggcgggtc gccgcgcagc gccagcatgt
     9601 tccgtacgcc cgctccggcg tacgcaccga tcaccgagcg caactcgtcc cgcgagtgcg
     9661 cgacacaggt gaggtggccg agcggtgtga gcgaggtgtc ctgcgccacc cgctcggtga
     9721 cccggatcgt gccgtcccgg gtggtgccgc cggcgccgta cgtgatcgag acgaaggtgg
     9781 gccggagctg ctcgatctcg cggatcgatc gccacagcac ctcctcggcc tccggcgtct
     9841 tcggtgggaa gaattcgaac gagaaggagc ggccaccggt cgccagcaga tcgcggatcg
     9901 tgggcgtacc gccggaaagc gtcgaaggaa gaccgtgggc catggcgata ggttacccgg
     9961 gccgtcggtg cacgcgcgcc caccggttac gctccgaggc gtgtatggcg acgtggacat
    10021 cccggccgag gtacagcggg cgctgaccgg cttcctggat ctgcagcaac agcgactcga
    10081 ggcgatcggg ccggagctgg ccgagcaggt gcaggccgcg cgggacgcga ccagcggcgg
    10141 caagcgactg cggccttcct tctgctattg gggtttccgg gccgccggcg gtgatccggc
    10201 acagccgatc ctgaaggccg cggccagcct ggagatgctg cacgtcagcg cgctggtaca
    10261 cgacgacgtg atggattcct ccgacgtacg acggggtgca ccggccgcgc atcggcgctt
    10321 cgaggccctg cagcgagccc ggtcgcagac ttccggggtc ggcggcgatg cggagcgctt
    10381 cggcatcgga gcggccatcc tgctcggcga tctgtgcctg atctgggcag acgagatgct
    10441 gcacacgtcg ggcttcgacg ctgccgcgct ggcccgcgcg gcaaggttct tcgacgccgt
    10501 acgagtcgag gtgacggccg ggcagtactt ggacctggtc gcccaggcca gcggcgagtc
    10561 ggacatggat caggccttgc gggtcctgcg gtacaagtcg gcgacgtaca cggtcgagcg
    10621 gccactgcac gtcggggcgg cgctgggtgg tggggatcag cgtctgatcg aggcgttgtc
    10681 ggcgtacgga ctgcctttgg gtgaggcgtt ccagttgcgc gacgacctgc tcggggtgtt
    10741 cggcgacccg gcgctgaccg ggaagccggc gggtgacgat ctgcgtgaag gcaagcggac
    10801 ggtgctgatc gcgtacgccg tcgaccacgc atcggaggtg cagctggccg agttcgaccg
    10861 gctgttcggg cggcccgatc tggatgacga cgagatccag ttgttgcgcg agatcctgca
    10921 ggactcacgc gccgtacagg cctgcgagga cctgatcacc gaccgcaccg aggacgccct
    10981 ggccgccctc gaccgcgctc ccctggctga tggcacggcc cgcaaggctc tggcggatct
    11041 ggcgatcgcg gcgacgtctc gccagctcta aggcgacgtc atcaggttga tcagccggag
    11101 cagctcagcc gtcggcgcca gatcgccgag gatgatcacc ttcagtacgg cgcgatcctc
    11161 gtcgtacacg gtctcgaccc ggagccggcc gacgccgctc tgattgagcg aaccgatcac
    11221 gtgcgtgctg atccggtccg cgccggcccg gtcgatcgcg tcgatgtgca cgatgctcga
    11281 cgcctccacg ttccgggccg tctcgtccac ctcgagcgcg gccgcgctgg tgccggtgaa
    11341 tgcctccagg tcctcgcggg cgatccggta ctgcttgccg atccggaccg ccttcagccg
    11401 gccgtcgcgc acgtagttcc ggatcgtgcg gacatgcaga ccgagccggt tcgccacctg
    11461 ctcgaccgag tacagctcct gaggcatgcc acctagacta cgtgcgattc cttagaattc
    11521 cctataaatc gccagatagg gatatttaag gtagttttgg tgcatgaacg ttgaaggggt
    11581 gcgggtgtac gtgagtgacg cccgcgtgca ggacgacggc gatgccgtgc agctcatcgc
    11641 ggacgcgcac tacgggcacc aggccgagtg ggtcgcggtc gacgccgagc agctggggga
    11701 cgatttcttc gagctgcgga ccgggcgcgc gggtgcgatc gcgcagaagt ttgtcaacta
    11761 ccggatgggg ctggccgtgg tgggtgacat cgcggagaag ctggcgggca gcaagccgct
    11821 gcgcgactgg gtacgggaga gtaaccgggg acggtcgctg tggttcgtca ccgacctgga
    11881 cgcgctggcc gagcggctac aggaccggca gtgagctgag caggtccggc gtatcggcct
    11941 cgctgcgttc acggatgagg acgcggagct ggccggagtt ggtggtgtcc tcggcgagga
    12001 tctgcagcgc cacgtcgacg gtgtcgtggt cgtgatcgag caggtggtgc agcccttccc
    12061 agaggacgat ttcgggctca ccggtggagc ggtcgctcag cgagtcggcc agcgcgtccc
    12121 agttgcgccc gaaccagcgc ggcaggtcga aggcggtcgc acacaggtcc aggaagccgg
    12181 tcttgtcgtg gatctctgtg gtgtcgagca gaacgaagtc ccagccggcg tcggcgacat
    12241 cacgtcgtac gtcgtccgga gtcaggtccg actgccagcg gtagacgccg gggcgcaggc
    12301 cctcggtcag cagcgtgggc aggtcagtca tccgtcgcac ccccgtccgc cgcgatccgg
    12361 cggaacgact tgtagtgatc gtcagtgtag taacgctcgc cattcttgcc ggtcacgatc
    12421 cgccgggcgc cgcgattgct ctcgcccggc gtcttcacgg tgtactcgtg gtagtacccg
    12481 cggtcctgct tcggcaggat cttctcgaag ttgccgaaca ccacaccgtc ccggctgtac
    12541 gggaacggac caccctgatc gatcagcttc agcgtctgct gcgcctcact cggcaggtca
    12601 gccaccgcca cgatcgtgag gccgctctcc ggatcagtac tgttcggctt ggccgcgctg
    12661 catccgaaca gcgaggccgc cagcgtgatc accagcatcg cgatcacgac tgctgcgatg
    12721 atccgcgcgg ccttcgggtt gttgatcacc cagcaccccg cagccgccta ctgaactcag
    12781 ccgctgcggc cgccgggtca tccgcctcag tgatagcccg tacgacgacc acgcgggtgg
    12841 ctccggcttc gacgacctgg tccagccgct cgaggtcgat gccaccgatg gcgaaccacg
    12901 gcttcgactg cggccggctg gcggcgtacg agacgagctc gaggcccgca gcctggcggc
    12961 ccggcttggt gggcgtctcc caggtcggac cgacgcagaa gtagtcggag ccctgctctg
    13021 tgactgctgc gttcacctgg ctgaacgtgt gcgtggagcg gccgatgatc ggcattgggc
    13081 cggtgatagc ccgtgctgcg tgcactggca ggtcccgctg gcccaggtgc agtacgtcgg
    13141 ctcccgcgac gaacgcgatg tccgcacggt cgttgaccgc cagcagcttg ccgtgccgct
    13201 tgcaggcgtc cgcgaacacc tccagcgccg ccagctcgtc cgcggcctcc atctccttct
    13261 gccgcagctg cacgatgtcc acgccaccgc ccagagcagc atccagcaac tgctcgaggt
    13321 cgccctgctt ctcccttgca tcagtgcata gatacagacg ggcgtcttcc agctgctcgg
    13381 tgtgctcagt cacaccgcca agcctgccat gcttcgctgg acgtaggctg acggcatgcc
    13441 tgagcacacg tccgatgtgg tggtggtcgg cgccgggctg atcggtcttt cgattgcctg
    13501 gcggctggct gcagacggta tccaggtgac ggtatgcgac ccgacccctg gcacccagac
    13561 ctccgcggtc gcagccggca tgctcgcccc ggtcactgag gtcgagtacg gcgaagacga
    13621 cctgctcgcc ctcaacctcg ccagtgtcgc cgcgtggccc tccttcgcag cagagctgga
    13681 ggaactcacc ggagtgcccg ccggcctcca ccagaccggg acgctgtcag tcgcgtacga
    13741 cgtcgacgac gcggccgccc tccgtcgcct cgccgactac cagcgccgtc tcggcttgga
    13801 agtcgaggtg ctgtccggtc gcgacgcccg caaacgcgaa ccgctcctcg ccacaggcgt
    13861 ctccggaggt gtctgggttc ccggcgacca ctccgtcgac aacaggcagg cagtgaccgc
    13921 actcctccgc gctgtggagc tgtccaaggt caccctgatc cgccagcgcg tctcccgcat
    13981 cctcacctcc ggtacgacgg ctgtcggcgt acaactggag aacggggaca cggtgcgggc
    14041 tgcgcacgta gttggtgcag cagggccgtg gtctgggcag ttggagggcg tgccgcagga
    14101 gctgcggccg cctgtgcgtc ctgtgaaggg tgaggtgctt cggctgcgtg tgcccgaggc
    14161 ttaccggccg gcgttgcagc acacggtgcg ggcgactgcg cgaggcttct ccgtctacct
    14221 cgtaccacgg ccgggtggtg agcttgtcgt gggcgccacc agctcggagc tcggctacga
    14281 caccagagtg cttgcaggtg gcgtgttcac gctgttgcgg gacgcgcgga ccgtactgcc
    14341 gattaccgac gagctggagc tggtcgagtc gatcgccggg ttgcggccgg ccacgccgga
    14401 caacgcgccg atcctcggac cgtccgggct cgaagggttg ctttgggcaa ctggtcacta
    14461 tcgcaacggc gtgctgctca caccgatcac cgcgcggatc atcgccgaca ccatccggac
    14521 cggcgtcgta ccggagctcg gagttccctt cctgggcagc aggttcgccc attccactct
    14581 gtagtacatc ggttgccgtc agcaatcaat gcttgtgaac tacatgcctg tagttcagcc
    14641 ttaaattgta aacattgagt tacaggcgta acaagcaccc cataagcccc tgttgtcaca
    14701 tccgtatctg cacttacggt caaaagacgt tcacacgggg agatgaatcg atggatgacg
    14761 cctgcacctc cagtcgacgc cggaccgtag tacgggttct gaccggactc gccgtaccgg
    14821 ttctgaccgc cgccgtcatc acggccggct cgcctggctt cggccagtac aaggtgaaga
    14881 acggcgacac gctgagccgg atcgcgaccc agtacggcac caccgtgcgg aatctggtcg
    14941 cgctgaacaa cctgcccggc aacggcaaca cgatctatgc cggcgagacg ctgaaggtcc
    15001 caggcggcaa gcagacgacc aagcgctccc agctcggccg ggttacctac atcgtcaaaa
    15061 agggcgacac gatctccaag atcgccaagc gcttcaagtg ctcacaggcg aacctgctgg
    15121 cggcgaacgg gctccgtgcc accgaccata tctacgccgg caagccgctg caggtgccgg
    15181 tcaagctcca cccgaagccc aagccgaagc cgaaggcgcc ggccaagaag aacaacagct
    15241 tcgccggccg cacctacccc gaccacgtcg tcgccaaggc ggaccagaac cgcgcgatcc
    15301 tgaagagccg caagctgcct acccgtgcac aaatgcgcaa cctcatcatc gccacctcca
    15361 agcattacgg cgtcgacccg gagctggccc tcgcggtgag ctggcaggag tccggctgga
    15421 agcagcgggt ggtctccccc gccaacgcgg tcggtgcgat gcaggtgatc ccgtcgaccg
    15481 gccggttcgc ctccagcgtc gtcggacgcg atctggatct gctgaagcca cgggacaacg
    15541 tcaccgccgg tgtggtgctg ctggaccggc tcaccagcgc cgccgagctc cagaccgctg
    15601 tagcgggcta ctaccagggc ctgggcggtg tgaagcgcaa cgggatgtac ccggacacca
    15661 agctctacgt gaagaacata ctgcggatca aggcgcagct ggagcgtggc tggagcccgc
    15721 tcaagtgagc aggcctcacc gactgcggtg agcctggcgc ggtcgcactg agcccttatc
    15781 tacactctca gtgcaggacg gcttcgagag gcggctcacc gcaagtgacg gacgacgtgg
    15841 acacgcaggt cagcgaccgc ctcgtcgggc gagtgctcga cggacggtac cgcgtgggcg
    15901 cacgcgtcgc caagggcggc atggccactg tctacaaggc cctcgacatg cggctggacc
    15961 gcgtcgtcgc actcaaggtg atgcacgacg ggctcggcga cgacgcccag ttcgcccgcc
    16021 ggttcgtggc cgaggcccgg gccgccgcgc ggctctcgca cccgaacgtg gtggccgtct
    16081 tcgaccaggg cgacgacaac ggcacgctgt tcctggcgat ggagtacgtg cccggccgca
    16141 cgctgcggga cgtgatccgg cagcaggcgc cgctctcccc cgcccgggcg ctggatctgc
    16201 tggcgccgat cctgtccgcg ctctccgcgg cccacgacgc tggcatcgtc caccgcgaca
    16261 tcaagccgga gaacgtgctc atctccgaca acggcgcggt gaaggtcgcg gacttcggtc
    16321 tggcccgggc ggtcagtgcg accggcaaca ccgcgaccca gggtctgctg atgggcacgg
    16381 tgtcctacct ggcgcctgag ctggtcaccg acggcagtgc ggacgcccgg tcggacgtgt
    16441 actcgtccgg catcctcctg tacgagatgc tgaccgggaa caagccacac tccggtgaca
    16501 ccccgatcca ggtcgcctac gcacacgtgc atgccgacgt accggcgccg tcgctggagc
    16561 agccgacgat cccgccgtac gtcgatgcac tcgtgcagcg cgcgaccgct cgggaccggg
    16621 acctgcggcc ggcggatgcg cgggtgctga gccggcaggt ccaccgggtg cgcagtgcgc
    16681 tcgaggaggg gctgccggac gacccggagc tcactggcga cttgaccgtt ccgatccagc
    16741 agatccgcca ggacagcggg tacgacgacg gctatacgcg cggtgacccg gaagacgccg
    16801 tgctgcgtca cgacacgatc gtcgtaccgg tggaacacgg gcgcccgacc ggtgcaccgg
    16861 cgacgcgggt gcaggcgcca ccccagcgta ggggccgcgg gctggtcgcg ctgatcctcg
    16921 tcctggctgc tgccatcggc gtcggtacgg cggcctggta ctacggcatc caccgctaca
    16981 ccaccacgcc gagcctggtg aagatggtgc cggcggacgc aacggcggag gctgagaagg
    17041 ccgggctgcg gaccaacctg gccaaccagg acttctccga ggacgtgccg aaggggcagg
    17101 tcatggcgac cgacccttct gcgggagacc ggatccggaa gaacggtgag atcaatctga
    17161 ccgtttccaa gggccctgag cgctatcggg tgccgcaact ggccggtctg gaactcgagg
    17221 ccgccaagcg ggcgctggac tcgatcaagc tgatcaccgg ccagatcaac gagcagtaca
    17281 gcgagaccgt gccggctggg cgggtgatcg cgttcagccc gaagttcgac gcagttgtga
    17341 agcccggtac ggcggtcaac ttcgccgtca gcaagggaaa gaagccgatc gcggtcccgg
    17401 acgtgaccgg caagacctac cgccaggcac gcgaggccct gcgtaatctc ggcttcgtgg
    17461 tcggccgcac ggaccagtac gacgagaaga tcgccgaggg caaggtgatc agccagaccc
    17521 ccaacaccgg cacgttgttc gccaaggaca aggtgcagct ggtggtgtcg aagggcccgg
    17581 cgctgcgtga ggtcccgaac gtgaaacgca agaccctcga cgaggcccag cagatcctca
    17641 ccgaagcagg cttcaaggtg cgggtcgaga aggcgccgtt caacctcggc ctcaacatcg
    17701 tcgcggccca gaacccgggg tccggcaaga tggcccagcc cggcaccacg gtcgtcgtca
    17761 ccgtgctctg attttgtccg caggacaagg cttctggtta gctgtgccgc gtgaatcacc
    17821 cgcgccttgc cgtcgttgcc ctgctcgcgg tcgcggcggc atggggatcc acgttcttcc
    17881 tgaccaagga cctgctcacc aggatggatg tcgccgacta cctggcgttg cgattcctga
    17941 tcgcctcggt cgcgctcgtc ctggtccacc cgccggccat cgcccggctg agccggctcg
    18001 accgcggccg ggccgttgcc ctcggcatca cctacggcat cgcccagctc ctgcagaccg
    18061 aaggcctgcg gcacaccgcc gcgagcgttt ccggcttcgt caccggcatg tacgtcgtct
    18121 tcacgccact gctggccgcg gtcatcctcc ggcacaagat cggccgctgg gcctgggtgg
    18181 ctgtgatcct cgccaccgtc ggcctcggcg tactctccct gcgcggcgtc agcatgggtc
    18241 cgggagaact tctcaccctc gcctcggcgg gcctgtacgc gttgcacatc atcggcctcg
    18301 gcgcctggtc gacctcggcc aacgcgttcg gcctctcgtc gttgcagatg atcaccatca
    18361 cggcggtctg cgcgatcggc gcgatccccg gcggcttctc gataccgggc accggcggcg
    18421 actgggtcag cgttttctac atggcactgg tctcgggcgc gctcgccctg atcgtgcaga
    18481 cctgggcaca ggcgcatctc accccgaccc gggcggcgat cgcgatgacg atggagccgg
    18541 tgttcgcgtc ggcgttcgcc gtactgttcg gctccgagag cgtgacgtgg cggatgctgg
    18601 tgggtggggc gctggtgctg tccgcgatgt atctggtcga actggcgccg cggcgtaagt
    18661 tcgaggccga ggtccagcac ctcgcacagt aggagggtcg gcagatgcgg gacgacagcg
    18721 cacggcgggt ccggcggttc ccggccgtcg tgatcgccgt cctgctggcg gttctggcgg
    18781 ccggtacggc gaacaacctg gcccgcaacc cgcagccgct gctcgttgcc cccggcaatg
    18841 tctcacgcgg ggacgacctg gccgggcaag cggtcctgga cctcgacgcg ttgactctcc
    18901 cgaacggcgc gacgctggcc ggcccggacg gcccgtggcg attcgtctgg ccgcgcgacg
    18961 cgtccttcgt cgctgcggcg cgctgctctc tcggtcaatt cgacgaagcc ggccgcgtgc
    19021 tggatttcct caacaaaata aggccttcca gcggtcgatg ggaagcacgc tattcgtccg
    19081 acggtttgct ggttcgggac ggacgcgagc cgcagctgga cggatccgga tgggtgctct
    19141 gggcaacctg gttctgccat gcggggagca gatactggga aatggtccgc gaatccgccg
    19201 accagatcgt tgccgaactc gggcccaacg gtctcccggc acgatcaccc gactattggg
    19261 aacggccgga acgtgtggtg acgttgggca ccatcgctcc cctgctgacc ggtctgcgag
    19321 ctgccgtcgc gatcgctcat gacctcgatc gtccggccga ggccgcacga tggcaggacg
    19381 cgctgaacaa gttgtcctca gcaacggatc ggtcgttcgg cccggacttt ccgcggacgc
    19441 cggcgcgtgc ggtgagcttc ctcgaaccag ggctcgagcc gatcggcctg ggtggcggcg
    19501 ccgatgcgat cgtcacggtt ctcggcccgc cctttgctcc gccccgcgac gacgtcgacc
    19561 acgcgatcga caacgctcgc gccgccctga cccagccgaa cggcggtgtc acccccggcg
    19621 aggactggcg caccgacggc gtctcctgga ccccacaaac cgccctcttc gccctcagcg
    19681 ccgccgcccg cggcgaccgc gccaccgcct ccagcctcct cacctggctg aaccactacc
    19741 gcaccagcac cggcgccctc cccgaaaagg tcaaccgcga cctccaaccc gccggcgaag
    19801 cccccctcgc ctggacctca gccctggtca tcctcaccca cgccgccctc caaacccccc
    19861 tccccatccc ctgacccgac ctcccgccga gtgaagccac cgtgcgagcc tcagcggatg
    19921 tggagtggcc ggagtgggtc agcagatctc catggactcg ttgcttgggg catcgggtcg
    19981 ggtcgtgctg gttttggctg agtagaagaa ggccgttgag gcgatgtcgt cctggagcgg
    20041 gaggtagcgg ccgcccgagc gccagccgag ggcttgtacg tcgactcgca gcttctcgcg
    20101 gaagcggatc gggtcgggca ggtggaagcg gtacatgccg aaccgctgct ggctcgcata
    20161 caaaccgtcc ggccggatca cctgcggcat gccgaggtac ggcgtactga actcggtgta
    20221 gccgtcgccc gggacatcga agttccaggc gccgccgaag tagtcctcgg taccggtgcc
    20281 gcagatggtc gggaactcgt cgtcgccgtc gacgtagaac ttcacctcac cctcgcccca
    20341 ccaaccgctg ctgttgacgc cccacgcgac gtacgtgccg acgtaatggc ccgggccctc
    20401 cacgccgtcg agcagggtgt gcacggtttt ggcctgtagc gggttgctcc gccgccactg
    20461 cgcatgcagg taggccgact gctccggtac ggcgcccagc cagtagtcga cctggaagta
    20521 cacgatcacc ggttcgtcgt gcgtgttctc gagcgtcagc ttggcctgtg actggaacgg
    20581 catctcccag tagctgttga agccgccgtt cgggttcacc gcgaccggga gcgagttgac
    20641 ctgcgcgaac ttgccccagc cggagcagaa gaagtcgccg accggcgtct cgatcgcggg
    20701 cgcctcgtcg ccgtcccagt acgagcgcag cacgagccgg cgccagtggt cgacatgcgt
    20761 ggtgagccag atgtgggtga tgcagccgga tccggcgatg tccgcgagta cggcggtctc
    20821 cccggcgccg atctcgatcg acggcgacac cttccagcct tggccgaggt cccgggccgc
    20881 gttcgccccg gtcccctcgg tccgccggcc gccctgaccg ggctcgccgg tcgggttctc
    20941 cgcactgatg gagcgcgtct cgacatcgag gatcgcactg attccgcaca acttcccaag
    21001 agtcataccc gcgaccctag gtctcccctg gtcgacaaga aatcgattgc ccgccacctg
    21061 gactctaata t
//
