LOCUS       NZ_CP028720            21008 bp    DNA     circular CON 21-NOV-2024
DEFINITION  Enterococcus faecalis strain CVM N48037F chromosome, complete
            genome.
ACCESSION   NZ_CP028720
VERSION     NZ_CP028720.1
KEYWORDS    RefSeq.
SOURCE      Enterococcus faecalis
  ORGANISM  Enterococcus faecalis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2997828)
  AUTHORS   Tyson,G.H., Sabo,J.L., Hoffmann,M., Hsu,C.H., Mukherjee,S.,
            Hernandez,J., Tillman,G., Wasilenko,J.L., Haro,J., Simmons,M.,
            Wilson Egbe,W., White,P.L., Dessai,U. and Mcdermott,P.F.
  TITLE     Novel linezolid resistance plasmids in Enterococcus from food
            animals in the USA
  JOURNAL   J Antimicrob Chemother 73 (12), 3254-3258 (2018)
   PUBMED   30272180
REFERENCE   2  (bases 1 to 2997828)
  AUTHORS   Tyson,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2018) CVM/OR, FDA, 8401 Muirkirk Rd, MOD2, Laurel,
            MD 20708, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 603x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004332015.1-RS_2024_11_19
            Annotation Date                   :: 11/19/2024 19:35:46
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,059
            CDSs (total)                      :: 2,981
            Genes (coding)                    :: 2,931
            CDSs (with protein)               :: 2,931
            Genes (RNA)                       :: 78
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 50
            CDSs (without protein)            :: 50
            Pseudo Genes (ambiguous residues) :: 0 of 50
            Pseudo Genes (frameshifted)       :: 30 of 50
            Pseudo Genes (incomplete)         :: 21 of 50
            Pseudo Genes (internal stop)      :: 15 of 50
            Pseudo Genes (multiple problems)  :: 12 of 50
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:04:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 894026
            Orig. end                         :: 915034
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP028720.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21008
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="darobactin"
                     /region_number="2"
                     /rules="((cds(PF04055 and (TIGR04085 or SPASM)) and
                     darobactin_precursor) or darobactin_rSAM)"
                     /tool="antismash"
     cand_cluster    1..21008
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((cds(PF04055 and (TIGR04085 or SPASM))
                     and darobactin_precursor) or darobactin_rSAM)"
                     /kind="single"
                     /product="darobactin"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21008
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11008](-)"
                     /cutoff="5000"
                     /detection_rule="((cds(PF04055 and (TIGR04085 or SPASM))
                     and darobactin_precursor) or darobactin_rSAM)"
                     /neighbourhood="10000"
                     /product="darobactin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11008)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="((cds(PF04055 and (TIGR04085 or SPASM))
                     and darobactin_precursor) or darobactin_rSAM)"
                     /neighbourhood="10000"
                     /product="darobactin"
                     /protocluster_number="1"
     gene            complement(158..1459)
                     /locus_tag="C7I32_RS04805"
     CDS             complement(158..1459)
                     /EC_number="2.4.2.2"
                     /GO_function="GO:0016154 - pyrimidine-nucleoside
                     phosphorylase activity [Evidence IEA]"
                     /GO_process="GO:0006213 - pyrimidine nucleoside metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /locus_tag="C7I32_RS04805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="WP_002356165.1"
                     /transl_table=11
                     /translation="MRMVDIIEKKRDGHQLTSEEIQFIINGYTDGSIPDYQVSAFLMAV
                     FYQDMTDEEITQMTLAMVHSGEIVDLSSIEGIKVDKHSTGGVGDTTTLILAPLVASVGV
                     NVAKMSGRGLGYTGGTLDKLEAIPGFKVELTEERFIQLVNDTKVAVIGQSGDLAPADKK
                     LYALRDVTATVDSIPLIASSIMSKKIAAGADAIVLDVTTGEGAFMKDLASARRLAETMV
                     RIGKLANRQTMAVISDMSQPLGEAIGNSLEIVEAIETLQGNGPEDLVEMCYVLGSQMVV
                     LAKKAETLDEARALLEEALTSGRALAKFKEMIENQGGDSSVVDQPEKLLTATYQFDLPA
                     KETGVVQKIVANEIGVAAMLLGAGRATKEDTIDFAVGLKLHKKVGSPVEKGESLLTIYA
                     NREDVTEVEQLLYKNIEIGPTGEEPILIHDIITE"
     gene            complement(1600..2607)
                     /locus_tag="C7I32_RS04810"
     CDS             complement(1600..2607)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002414878.1"
                     /locus_tag="C7I32_RS04810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="substrate-binding domain-containing protein"
                     /protein_id="WP_002356164.1"
                     /transl_table=11
                     /translation="MKLTIKEIADMAGVSVTTVSQILNNKGSRFSEKTRNKVLAVVAEN
                     HYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKVIEGVETYLNSLGYMILLCNSKHDSE
                     QAMQYVSELIHRSVDGIIFATPNVLPENHILKDRREHPIPVILVDRGINPRDSGRLIVK
                     EYEGAYQAVHHLIQQGHQHIGMLRESAGYYRLTERVTAYQHALQDNNLPFRPHYVCAGE
                     LNLHGGYAAAKEVLKNEEITAIFCGNDEMAMGAYQAIEEAGKKIPDDISVVGFDGLEIS
                     EYLVPSLTTVYQPSFDIGYYAAKFLVEAIADPTGKVPNKVFDATFIARKSTKPI"
     gene            2749..3780
                     /gene="add"
                     /locus_tag="C7I32_RS04815"
     CDS             2749..3780
                     /EC_number="3.5.4.4"
                     /GO_function="GO:0004000 - adenosine deaminase activity
                     [Evidence IEA]"
                     /GO_function="GO:0019239 - deaminase activity [Evidence
                     IEA]"
                     /GO_process="GO:0043101 - purine-containing compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /gene="add"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408236.1"
                     /locus_tag="C7I32_RS04815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="adenosine deaminase"
                     /protein_id="WP_002356163.1"
                     /transl_table=11
                     /translation="MEAIFFMEESRVRQLPKIELHCHLDGSIRPTTLRTIAEKQNIPLP
                     QDEQALKELVVAPEKCTDLNDYLTRFDFVLTCLQTAEALQAAAYDVISQAAEDGVAYIE
                     VRFAPSQHTEKGLRLPEIVTAVLTGLKQGEEDFGVKSNALLCGMRHDQQQAIEKIVHLA
                     HDFRETGVVGFDLAGNEVDFPPYTFEDVLALANQLSIPLTLHAGECGCGKNVADAVTLG
                     ATRIGHGIALKDTPEYLALLKEKKVLLEMCPTSNFQTGTVKTLAEYPFQQFIEAGLAVC
                     INTDNRTVSDTTLTKEFMKLATWYQLSYDEMKQLTKNALAGAFLSPDEKKLLNQKIDQA
                     YLF"
     gene            complement(3813..4421)
                     /locus_tag="C7I32_RS04820"
     CDS             complement(3813..4421)
                     /EC_number="2.1.1.172"
                     /EC_number="2.1.1.174"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0052916 - 23S rRNA
                     (guanine(1835)-N(2))-methyltransferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616699.1"
                     /locus_tag="C7I32_RS04820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_002356162.1"
                     /transl_table=11
                     /translation="MANHYYTENPELAHDLESWSFPLRGRTFQFTTDSGVFSRGTVDYG
                     SRVLIDAFEWENLPAGRLLDVGCGYGPIGLSLAAATGRLVEMVDVNQRAVGLAQMNAQR
                     NQITTVDIHSSNVYETLNETTYAAIVSNPPIRAGKKVVHGILTGAFPLLKVGGTLTVVI
                     QKKQGAPSAEKKMAEVFGNVEIVTKDKGYYILRSVKEAE"
     gene            complement(4436..5023)
                     /locus_tag="C7I32_RS04825"
     CDS             complement(4436..5023)
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002396143.1"
                     /locus_tag="C7I32_RS04825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_002356161.1"
                     /transl_table=11
                     /translation="MRKIVLFGDSITAGYLDEAVSPVLVDLVKRDIAAMGLEEVAVINA
                     GMPGDTTEDGLKRLNKEVLIEKPDEVVIFFGANDASLDRNITVATFRENLETMIHEIGS
                     EKVILITPPYADSGRRPERPQTRIKELVKVAQEVGAAHNLPVIDLYKAMTVYPGTDEFL
                     QADGLHFSQVGYELLGALIVREIKGRLKPKQA"
     gene            5178..6101
                     /gene="coaA"
                     /locus_tag="C7I32_RS04830"
     CDS             5178..6101
                     /EC_number="2.7.1.33"
                     /GO_function="GO:0004594 - pantothenate kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="coaA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /locus_tag="C7I32_RS04830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type I pantothenate kinase"
                     /protein_id="WP_002356160.1"
                     /transl_table=11
                     /translation="MDDKMNYYPISREEWHGFYHDGKAPLTEAELDNIKSVNDQISLKD
                     VQEIYVPLTHLIHLYMKEFESLTLSKGLFLHEYVSVPPFIIGIAGSVAVGKSTTARLLQ
                     RILARTFKRRNVQLITTDGFLYPNKVLEEQGIMDRKGFPESYDMEKLINFLNEVKSGKD
                     EIKAPVYSHSVYDVIEGEYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSIFVDAD
                     PALIEKWYLERFGALLDTAFLDPNNYYYQYAIGKREDAFAMARNVWKTVNLPNLEEYIL
                     PTRGRADIILHKTENHLIDQIYLRKY"
     gene            6413..7975
                     /gene="guaA"
                     /locus_tag="C7I32_RS04835"
     CDS             6413..7975
                     /EC_number="6.3.5.2"
                     /GO_function="GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016462 - pyrophosphatase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="guaA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1249: carbamoyl phosphate synthase small subunit"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /locus_tag="C7I32_RS04835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="WP_002356158.1"
                     /transl_table=11
                     /translation="MTNVADLTSVEKIIVLDFGSQFNQLITRRIREFGVFSELLSHRTT
                     AEEIRKIAPKGIIFSGGPNSVYDKDAFSIDPEIYELGIPILGICYGMQLMTHNLGGKVE
                     PAANREYGKAELEILGDATLFQGTPAKQTVWMSHGDLVTEIAPGFEKVGTSNDCPIASI
                     EDANRKFYGVQFHPEVRHSEYGNDLLRHFAFDVCGCTGDWSMENFIDMEVAKIREQVGD
                     KKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHGLLRKGEAEQVMESLGGKFGLNII
                     KVDAKERFLSKLAGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQGTLYTDVI
                     ESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGTELGMPDAIVWRQPFP
                     GPGLGIRVLGEITEDKLQIVRDSDAILREEIAAAGLDRDIWQYFTVLPGIRSVGVMGDG
                     RTYDYTVGIRAVTSIDGMTADFARIPWDVLQKISVRIVNEVAHVNRIVYDITSKPPATV
                     EWE"
     gene            complement(8168..9523)
                     /locus_tag="C7I32_RS04840"
     CDS             complement(8168..9523)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010819693.1"
                     /locus_tag="C7I32_RS04840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PIN-like domain-containing protein"
                     /protein_id="WP_010819693.1"
                     /transl_table=11
                     /translation="MANLKELFPEFYQSKLDMKDLSSESENLLVLDTNYLLDIIQLPTT
                     VSKKYIEALEKVKENIYIPYLVALEFNFKKSSLKKGKIKKIRKYKNEIEQSVVNINKKI
                     NEIDLVDKEEKEIFTNELLTMTEDYLAELKKVIDSKVSSMITEEENELYERLISVIENK
                     VGNKYSQEWIDEIEKEGEERYKQNIPPGFNDSSKEDEIDSLRMYGDIKYCRKYGDLIIW
                     KDIIEYSKEYTKMGKKVVFITNDGKAKQKRDLLYKVDDFTVGPNIHLMNELYMESNKEL
                     HILNNLRFVQLVNDLSDVEMSKLKKSSEKMYRVKIPHDQIEEERIKLLKKSIENNEYEF
                     GISDDGYLFKKEKNHIDNLYNSTIEDIERKKLIKYINMINHGGNHDRSKEEFYKMYLLN
                     KLTESELKDYKQMELWDKDDRSNKMSYDSESRKFIFNFDDDLEDNFDNEENE"
     gene            complement(10001..11008)
                     /locus_tag="C7I32_RS04845"
     CDS             complement(10001..11008)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     darobactin: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     darobactin: SPASM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     darobactin: darobactin_rSAM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     darobactin: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002394592.1"
                     /locus_tag="C7I32_RS04845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="radical SAM/SPASM domain-containing protein"
                     /protein_id="WP_010819692.1"
                     /sec_met_domain="PTHR43273 (E-value: 2e-38, bitscore:
                     129.7, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 4e-22, bitscore: 76.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 3.2e-14, bitscore: 50.8,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 8.2e-12, bitscore: 42.4,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 4.3e-08, bitscore: 30.9,
                     seeds: 166, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 3e-09, bitscore: 34.5,
                     seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="darobactin_rSAM (E-value: 1.0, bitscore:
                     1.0, seeds: 0, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSFELRSVYLEVGSLCNLKCKHCYNKSGSGMYRFSEDQILSIFK
                     EISKLKCQNVIISGGEPLLYKNLINLLRIGKQKYGLCIGLVTNGTMVDDYLAQRLSNVV
                     DYVQISIDGTTPEENDAVRGKGTFQKAIYAIELFEKYKIKTVVNFVITGKNTSKLAPFL
                     SALKSKNVSVISFKEIINIGRSKGEKPVSGEFFRSIVKELLLLMEELQDDNFEIKPPYV
                     SNSRCPLYFENNYTPTLEIRISYTGEVFLCQKFETEKVFSLGNVNVDLLTDIMQSEKYV
                     DLFSLIDVSTKFIKKCEGCFFTEMCFRECPATIISNGFFDYQDQLCDIRHFGMD"
     gene            complement(11011..11856)
                     /locus_tag="C7I32_RS04850"
     CDS             complement(11011..11856)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002394593.1"
                     /locus_tag="C7I32_RS04850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PqqD family protein"
                     /protein_id="WP_002394593.1"
                     /sec_met_domain="PF05402 (E-value: 2.9e-09, bitscore: 34.5,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLIQKRFLEFKPCLIENYLIYYRFEHGGYVTIKTIVNSQKTELVN
                     STYYYILTMCDGVNSVENIIDKIMAKYIGAPKSLIEKDVIKTIEKLSICGGLKLKDNPF
                     FVKESIHLSNELSISYDISACYSSLLKLILQEKGDCLRIFKNPFYDDLFVNSLILNRDF
                     ELNKSTIVLMIIDNLRKTNCGFMIWNIQNKNNVILQYYCRNKNIEVFDEKILKNGIALT
                     TKLLKQRSLTYKVFCIQNNLESQSLISNIKNLKFRHINSYKKEVRSQNVDEYQFNFGGI
                     "
     gene            complement(11877..12857)
                     /locus_tag="C7I32_RS04855"
     CDS             complement(11877..12857)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF015983.5"
                     /locus_tag="C7I32_RS04855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="radical SAM/SPASM domain-containing protein"
                     /protein_id="WP_010830586.1"
                     /sec_met_domain="PTHR43273 (E-value: 5.5e-38, bitscore:
                     128.3, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 2.7e-18, bitscore: 64.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 1.3e-06, bitscore: 25.5,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 2.6e-10, bitscore: 38.1,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNIVRGPININFDITNRCNLNCLHCYNSSGEGDFSFELSDNEVL
                     NIVDQIIEMKPYNVCICGGETLIRKRLVLKVLEKLTKANISCGMVTNGILLTEELAKSL
                     KKKGINNIQISLDGKKWAHNNLRNNKNAYDGAIRGLKLLSKYNIISGIAFSPTKWNISE
                     FDSVFSLAEELGVHEVRLQDLMPVGRAEKNLHILPSEKEYRQLKKEYNKKILENLNGKT
                     NVNVAWGDPIDHLLVFTESFSNSSYTDTICILSDGSITPSIYLPKTFGNLRKHTLSEYW
                     IGGLNQIWGSEHIISMVSKLTSVKQMTTPSNNTQSNRSTEFDILN"
     misc_feature    complement(12830..12850)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 24.09"
                     /tool="antismash"
     gene            complement(12892..13362)
                     /locus_tag="C7I32_RS04860"
     CDS             complement(12892..13362)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002394597.1"
                     /locus_tag="C7I32_RS04860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_010819691.1"
                     /transl_table=11
                     /translation="MYKHVNEGDTGDLMLFLKTLSEEGGSSFFDNTNIMKMQVNSISLA
                     RYYLYKKEQEVIYDESKENFIGLFVENNYRNSASINFIFLKNDSQMKLQEMINYIKNEM
                     VSFLVKEVNKLVIDLDSNTEFFKVWENRILAVGFNKCTLAKESRLFTYELLL"
     gene            complement(13436..13624)
                     /locus_tag="C7I32_RS04865"
     CDS             complement(13436..13624)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002394598.1"
                     /locus_tag="C7I32_RS04865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_002394598.1"
                     /transl_table=11
                     /translation="MNEQNFSEEQKKYQSPSSQNFYGSEIQPTSSTVFGIVMVFTVVAA
                     YWVVNSFKPCKCYGNIA"
     gene            13827..15419
                     /locus_tag="C7I32_RS04870"
     CDS             13827..15419
                     /EC_number="7.-.-.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002394599.1"
                     /locus_tag="C7I32_RS04870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_002394599.1"
                     /transl_table=11
                     /translation="MLLFLSNYFKQAKKKILIFSILNMLIAFISAVVPLISGNFIDSLV
                     SSHDYQIIIKFIIILCLFVFAQLSLGYVVQVQEAVLQAHLTYNIQKDILNQLQKTQIYL
                     ISQYDLANLSQRISSDSSSISSFMISSGSSLLVCCLNFFFSTILLFIVKWEIALFILVF
                     LVLYILYFYKLQNNLTVKQKDVKNDFSYYFSQIFSQLKNLKNLKIFSLYNYYGISLFDS
                     YNKYIYSLKKFKIFSFRLTSGDTLLAFFAQIVIFIFGGVSVINGNMTIGIFSVLLSYFN
                     MMLNSIKYIPSLTSSYAEMFASYSRITELINLEKDNTGKLKYSDNNFLEIKNLTYKYPG
                     SNTYLFSKFNYSFQKGNIYCLKGRNGSGKTTLLDIISKLKFSYNGSIELNQRNIELFDT
                     KYYRDVCLSYMTQDAFVIKAGLKDNILSQNLSEKLSTLIQELGLEKYIDSNYNINTKIS
                     GGEKQKISFLRSITKPFNILLLDEPTNHLDFISKEILMKYLNNIKNDAIIIISSHDNFV
                     LERVDTIIDLNKS"
     misc_feature    15441..15456
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 22.86"
                     /tool="antismash"
     misc_feature    15696..15711
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: medium, score: 25.8"
                     /tool="antismash"
     gene            17024..17320
                     /locus_tag="C7I32_RS04875"
     CDS             17024..17320
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408190.1"
                     /locus_tag="C7I32_RS04875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_010819690.1"
                     /transl_table=11
                     /translation="MSKETFLKYGFVVLFIGIFLLRAQKFISEPLSYLFSGILLLIVAY
                     LILVKKMNFFSSLLTITDQPSSTQQRLGQLSGLVSLLIGLLLVILSFIFFLQL"
     gene            17471..18016
                     /locus_tag="C7I32_RS04885"
     CDS             17471..18016
                     /EC_number="2.5.1.17"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002399092.1"
                     /locus_tag="C7I32_RS04885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP:cob(I)alamin adenosyltransferase"
                     /protein_id="WP_002387479.1"
                     /transl_table=11
                     /translation="MEKMYRSPYEAYPYLSSKPEDLRCDFELMTDELASMTGLLRGYVQ
                     QLDVPEQPALTEELAKICELIYHVNPTTRTKLTVTEDEIAWLLERVNAMNELTYEENRP
                     FVLPMGTICSSYAHILRAKAKDIVRLLYRMDYGGKKIDPQLYDVVNLLSGYFFMLALYL
                     NQLENGEEVPFVSRNYSI"
     gene            18031..18474
                     /locus_tag="C7I32_RS04890"
     CDS             18031..18474
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010824957.1"
                     /locus_tag="C7I32_RS04890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MepB family protein"
                     /protein_id="WP_002379245.1"
                     /transl_table=11
                     /translation="MNSLPILEKAVGTITLLSEEKQNAEYEGFLCQVNESQQLIRSRLA
                     KKTPKKEGYFVAFWEKNQQNQNEAFDATEAPEMLAIVIADQEKQGLFLLPKECLIQQKI
                     LKTHQQKGKMAARFYPSWCQNLNQTAKKTQKWQLTYFTDLSKY"
     gene            complement(18524..19792)
                     /locus_tag="C7I32_RS04895"
     CDS             complement(18524..19792)
                     /EC_number="3.5.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016634322.1"
                     /locus_tag="C7I32_RS04895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="RidA family protein"
                     /protein_id="WP_010830585.1"
                     /transl_table=11
                     /translation="MSNENIVLARNTERAPKHPLAAQTVAFSHYNHLSAQLPIEPTSGQ
                     LVEGGIRAQATQCLKNIQAVVESINHVMSDIVRMTIFVKDMRDVTAVEEVYAAFFTHYY
                     PAKTVVAVADLPLGASVQMEALVSNGEGTIPNAPQAGDLIKLTNQTVQAPIDALASQTV
                     AFSHYNNLSAQLPIDPQTGRVVAGCVKTQTKQCLKNIKAILTSIDVPFDDIVKVNIYLK
                     DLSKLEAVNQVYAAFFPDSGIARTVNYMPARTVIAVADLPMGAAVQVEAVVSHGDGTPP
                     QAIEDRHGLIIEANNTDHAPKCPFSTQTVAFSHYNHLSAQLPLDPKTNALVAGGIKEQT
                     TQCLENIKAIIESVDHSLADLVKVNIFVKEIEELAAVDDVYQTYFPEGTPARRVIGVTD
                     LPKGAQIQIEAIAGNAEGTPPIG"
ORIGIN
        1 cgacccaaca aggattgata catacagaga aaaagttgta ctccttagct tcgtcaataa
       61 ttttttggac agcggcttct gtcgcttctg gtttcaaaat agtgtggtca atcatgcggt
      121 ttaattccat gatgagaatt cctcttttct ttttgtttta ttccgtaatg atatcgtgaa
      181 tcaaaatagg ctcttcgcca gttggtccaa tttcaatgtt tttataaagc aattgttcga
      241 cttctgtcac gtcttcacga ttggcataaa tggttaataa tgattcgcct ttttcaactg
      301 ggctccctac ttttttgtga agtttcaagc caactgcaaa atcaatcgta tcttctttcg
      361 tagcccgacc agcgcccagc aacattgcgg caacgccaat ttcattggca acgatttttt
      421 gtaccacgcc tgtttctttg gcaggtaaat caaattgata agttgcggtt aataattttt
      481 ctggctggtc aacaacggaa ctgtcgccgc cttgattttc aatcatttct ttaaatttcg
      541 cgagcgctcg accgcttgtt aatgcttctt ccaataaagc ccgtgcttcg tctaacgtct
      601 cggctttttt agctaaaacg accatctgac ttcctaagac atagcacatc tccactaaat
      661 cttctggtcc atttccttgc aaggtctcga ttgcttcaac gatttctaaa ctgtttccga
      721 tggcctcccc taaaggttgt gacatgtctg aaattactgc catcgtttgg cgatttgcca
      781 gtttcccaat gcgaaccatt gtttccgcta atcgacgagc acttgctagg tctttcataa
      841 aggccccttc accagtagtc acgtctaaga caatcgcatc tgcccctgcg gcaatttttt
      901 tactcataat ggaacttgca attaatggaa ttgagtcaac agtggcggtc acatcgcgta
      961 acgcataaag ttttttgtct gctggtgcta gatcacctga ctgaccaatc actgccactt
     1021 ttgtatcgtt caccaattga ataaaacgtt cttctgtcaa ttcaacttta aaaccaggaa
     1081 tcgcttctaa tttatccaac gtaccgcccg tgtagcctaa gccacgacca gacatttttg
     1141 ctacattgac cccgacacta gcaactaacg gcgctaaaat aagcgtcgta gtgtcgccta
     1201 cgccacctgt agaatgcttg tcgactttga ttccttctat agaagaaaga tccacaattt
     1261 cgcctgaatg gaccattgct aacgtcattt gtgtaatttc ttcgtctgtc atatcttggt
     1321 aaaaaacagc cattaaaaag gcacttacct gataatctgg aattgaacca tctgtgtatc
     1381 cgttgataat aaattgaatt tcttcgcttg ttagttgatg cccgtcacgt ttcttttcaa
     1441 taatgtctac cattctcatg aattcgttcc ctccgatttc ccgataatgt attatacaac
     1501 aaaatcgttc agctttaaac catttagtaa accagtttac tattattttt ttcttgtgaa
     1561 aacgcaaaca acacgaacgt tctatttcta atctgttttt taaatcggtt ttgtgctttt
     1621 tctagcaata aacgtcgcat caaaaacttt atttggaact ttccctgttg gatctgcaat
     1681 agcttccacc aaaaattttg ctgcataata gccaatatca aaactcggct gatagacggt
     1741 tgttaaactc ggcaccaaat attcggaaat ttccaagcca tcaaaaccaa ccaccgaaat
     1801 atcgtcagga attttcttgc ccgcttcttc aatggcttga taagctccca ttgccatttc
     1861 atcattgcca caaaaaattg ctgtgatttc ttcatttttc aaaacttctt tcgccgcagc
     1921 atagccgcca tgcaagttca attccccagc acaaacataa tgcggacgaa aaggtaaatt
     1981 gttgtcctgt aacgcatgct gatacgccgt cactcgttcc gttaaacgat aatagccggc
     2041 actttcacgc aacatgccaa tatgctgatg cccttgttga atcaaatgat ggaccgcttg
     2101 ataagcacct tcgtactctt taacgattaa tcgtccacta tctcgtggat taatcccacg
     2161 atcgacaaga atgacaggaa tcggatgttc tcgtcggtct tttaaaatat gattttctgg
     2221 caaaacattc ggcgtggcaa aaataatgcc atccaccgac cgatgaatca actcgctaac
     2281 atattgcatc gcttgctcgg aatcatgctt tgaattgcat aacaaaatca tgtagcctaa
     2341 cgaatttaaa tatgtttcta caccttcaat cacttttgag aaaaagaaat ccgtcacatc
     2401 tggcacaatc ataccaatgg ttttggaatg acggttgatt acattcgaag caaagtaatc
     2461 tggtttgtaa tgattttcag cgactaccgc caacaccttg ttgcgggttt tttcactgaa
     2521 acgactccct ttattattca gaatttgtga gacggttgtg acagaaacac cagccatatc
     2581 agcaatttct ttaatcgtta gtttcatcgc gcccctccca acgtctcctt ttgcattgac
     2641 agacatttgt agacgtgtta cagtcttcaa aatacttatc gaatctttta cattttaaca
     2701 aaaaaaagac aaaagaaata gactaaaaag attaaaaaac aaaagaaaat ggaggctatt
     2761 tttttcatgg aagaatcccg tgtccgtcaa ttaccaaaaa tcgagctgca ctgtcactta
     2821 gatgggtcga ttcgaccaac cactttacgc accattgctg aaaaacaaaa cattccatta
     2881 ccccaagacg aacaagcctt gaaagagtta gtggttgccc ctgaaaaatg caccgatttg
     2941 aatgattatt taactcggtt cgacttcgtg ctaacctgtc tacaaacggc cgaagctttg
     3001 caagcagcgg cgtatgacgt gattagccaa gccgccgaag atggcgtggc ttacatagag
     3061 gtgcgttttg cgccttccca acatacagaa aaaggcttac ggttacctga aatcgtgact
     3121 gctgttttaa ctggcttaaa acaaggcgaa gaagattttg gtgtaaaaag caatgcactg
     3181 ttatgcggca tgcggcatga ccaacaacaa gccatagaaa aaatcgttca cttagcgcat
     3241 gatttcagag agacaggcgt tgtcggcttt gatttagctg gcaatgaagt cgatttccct
     3301 ccatacacat ttgaagacgt attagcttta gccaaccaat tgtcaattcc attaacactc
     3361 cacgctgggg aatgcggctg tggcaaaaac gtcgctgatg ctgtcacttt aggtgctact
     3421 cggattggtc acggtattgc tttgaaagat acacccgaat acttggcgct cttaaaagaa
     3481 aaaaaggttc ttttagaaat gtgtccaact agcaacttcc aaacaggcac cgtcaaaaca
     3541 ttggctgaat acccttttca acaatttata gaggctggct tagccgtctg catcaatacc
     3601 gataatcgca ctgtttcaga tactacgtta acgaaggaat tcatgaaatt ggccacttgg
     3661 tatcaattaa gttatgacga aatgaagcaa ctcactaaaa atgcgcttgc aggtgctttt
     3721 ttatcgccag acgaaaaaaa actgttgaac caaaaaattg atcaagcata tctattctaa
     3781 aaaagaacct ccactaaagt ggaggttctt ttttactctg cttctttaac acttcgtaaa
     3841 atataatagc ctttgtcttt tgtcacaatt tcaacattgc caaatacttc agccattttc
     3901 ttttctgcac taggtgcacc ttgtttcttt tgaataacta ccgttagtgt gccaccaact
     3961 ttcaacaacg gaaaagcccc tgttaaaatg ccatggacaa cttttttgcc tgcacgaatg
     4021 ggcgggttgc taacaatcgc cgcgtaggtc gtttcgttta aggtttcata cacattggaa
     4081 gaatgaatat ccacagtagt aatttggtta cgttgggcgt tcatttgagc tagcccaact
     4141 gcccgttggt tgacatccac catttccacc agtcgaccag tcgccgctgc taaggacaac
     4201 ccaattggtc catagccaca accaacatct aacaaacggc ctgctggtaa attttcccat
     4261 tcaaaggcat caatcaacac acgagaacca taatccactg ttcctcttga gaagaccccg
     4321 ctatcggtcg taaactgaaa ggtccgacca cgtaatggaa aagaccagct ttctaaatca
     4381 tgtgctaatt ctggattttc tgtataataa tgattcgcca ttttgttctt cctatctatg
     4441 cttgttttgg ttttagtcta ccttttattt ctcgaacaat caaggcacct aataattcat
     4501 agcccacttg tgaaaaatgc aaaccatccg cttgtaaaaa ttcatccgtt ccaggataaa
     4561 cagtcatcgc tttatacaaa tcaataactg gcaagttatg tgccgctccg acttcttgtg
     4621 caaccttgac caattccttg atacgcgtct gtggacgttc tggacgtctg ccactatccg
     4681 catatggtgg cgtaattaaa atcacctttt ctgaaccaat ttcgtgaatc attgtttcaa
     4741 ggttttctct aaacgtggct actgttatat ttcgatccag tgacgcatca ttggcgccaa
     4801 agaaaatcac cacctcatca ggtttctcaa ttagtacttc tttatttaat cgttttaaac
     4861 catcctctgt tgtatcgcca ggcattccag cattaataac agccacttct tctagaccca
     4921 tcgcagcaat atcccgtttc actaagtcaa caagaacagg tgagacggct tcgtctaaat
     4981 aaccagcagt aatgctatca ccaaataata caatttttct catggctttt cccctctttt
     5041 ctaacagttt tctcttttca tgataccatt ttcatcataa attggcgaag aagggaattc
     5101 ttttgtaaaa tcctgtgttt cccttgtgaa attatggtaa aatgtacaaa gattgaacag
     5161 ggtttggtgg aggaacaatg gacgataaaa tgaattacta cccaatttcc agagaagaat
     5221 ggcatgggtt ttatcatgac ggcaaagcac cgttaaccga agcagaattg gataacatta
     5281 aaagtgtgaa cgaccaaatt tcactaaaag atgtacaaga aatttatgta cccttaacgc
     5341 atcttattca tttatacatg aaagaatttg aatcgctaac acttagcaaa ggattattcc
     5401 tacatgaata tgtctctgta ccaccattca tcattggaat tgccggcagt gtcgccgttg
     5461 gtaaaagcac caccgctcgt cttttgcaaa gaattctggc ccgaacgttt aaacgaagaa
     5521 acgttcaact cattacaacg gatggatttt tgtatcccaa taaagtgtta gaagaacagg
     5581 gaattatgga ccgaaaaggg tttcctgaaa gttatgacat ggagaagcta attaatttct
     5641 taaacgaagt caaaagcggc aaagacgaaa ttaaagcacc tgtctattct cacagtgtct
     5701 acgatgttat cgaaggcgaa tatgagttga tacaacaacc agatattctg attgttgaag
     5761 gcattaacac attacagtta cccgccaatc aacaaattta tgtgagtgat ttttttgatt
     5821 tttctatttt tgtagatgcc gatccagcct taattgaaaa atggtaccta gaacgttttg
     5881 gggccttatt agatacggct ttcttagatc ctaataatta ttattaccaa tatgcaattg
     5941 gcaaacgaga agatgctttc gccatggcac ggaatgtttg gaaaaccgtg aacttaccga
     6001 acttggagga atatatcttg ccaacgcgcg gacgtgcgga cattattttg cataaaacgg
     6061 aaaatcattt gattgaccaa atctatctac gtaaatatta agggttgacg agctaagaaa
     6121 tatcctgtat cttttgtaga aatatccttg aaaattttca gcagaatgca tgactttcaa
     6181 ggagtaaaat gttttaataa gtatagctag acaaagaaga gtacggaaca aaagtgaacc
     6241 actttttaac cgcctgattc tcggctgttt aaaagtagcc cctgcggaat taagccaaaa
     6301 ttttctaaaa atcgtaaaac aatttttgaa aatcctttct taattcttgg tgctgaccac
     6361 tttttaaccg ccttttcttt agataaattt aaatggataa ggggtaatag acgtgactaa
     6421 cgttgccgat ttgacatctg tcgaaaaaat tattgtttta gactttggta gtcagtttaa
     6481 ccaattgatt actcgtcgta ttcgtgaatt tggcgtattc tctgagttat taagccaccg
     6541 aactacggca gaagaaattc gcaaaatcgc gcctaaagga atcatcttct caggtggacc
     6601 aaacagcgtg tatgacaaag atgcttttag cattgatcca gaaatttatg agttaggaat
     6661 tcccattctt ggcatctgct acggtatgca attaatgact cataacttag gcggaaaagt
     6721 agaacctgcc gcaaaccgtg aatacggaaa agcagaatta gaaatccttg gtgatgcgac
     6781 cttattccaa ggaacacctg cgaaacaaac cgtttggatg agccacggtg atttagtaac
     6841 agaaatcgct cctggattcg aaaaagttgg gacaagcaac gattgtccaa tcgcttctat
     6901 cgaagatgcc aaccgcaaat tctacggcgt acaatttcac ccagaagttc gtcattcaga
     6961 atatggtaac gacttattac gtcactttgc ttttgatgtg tgtggctgta ctggtgactg
     7021 gagcatggaa aacttcatcg atatggaagt cgctaaaatc cgtgaacaag taggcgataa
     7081 aaaagtctta cttggtttat caggtggcgt tgactcaagt gttgtcggcg tgcttttaca
     7141 aaaagccatt ggcgaccaat taacttgtat cttcgttgac catggattat tacgtaaagg
     7201 tgaagcagaa caagtaatgg aaagtttagg cggtaaattt ggcttaaaca ttattaaagt
     7261 agatgcgaaa gaacgcttct taagtaaatt agcaggcgtt tctgaccctg aacaaaaacg
     7321 taaaatcatc ggtaacgaat ttgtgtatgt ttttgatgac gaagcaacta aacttgctgg
     7381 ggaagaaggc gtttcattcc tagcacaagg aactctttac acagacgtca tcgaatctgg
     7441 tacagaaact gcgcaaacaa ttaaatcaca tcacaatgtt ggtggtcttc ctgaagacat
     7501 gcaatttgaa ttaattgaac ctttaaatac attattcaaa gacgaagttc gtgccttagg
     7561 aactgaactt ggcatgcctg atgcaatcgt ttggcgccaa ccattcccag gaccaggatt
     7621 aggtattcgt gtgcttggtg aaattacaga agataagtta caaatcgttc gtgattcaga
     7681 tgctatccta cgtgaagaaa tcgcagcagc tggcttagat cgtgacattt ggcagtactt
     7741 tactgtctta cctggcatcc gctcagtagg cgttatgggc gatggccgta cctacgatta
     7801 cacagtcggt atccgtgctg tgacttctat cgatggcatg accgctgact ttgcccgtat
     7861 cccttgggat gttttacaaa aaatctctgt gcgcatcgtg aacgaagttg cacatgtaaa
     7921 ccgtatcgtg tacgatatta cttcaaaacc acctgcaact gtggagtggg aataaataat
     7981 gaaaccgtga aacctttgat attagagggt ttcacggtta ttttttattt tgtgcaacca
     8041 atacattcta ggtaaattac tttttccctt cacattgctt tactaataaa atactgcaga
     8101 aaaaagactt attcaaattg taaatctaat taaaataagt ctttgttatt atatattaat
     8161 ttttcaatta ctcgttttct tcattgtcaa aattatcttc taaatcatca tcaaaattaa
     8221 aaatgaactt tctagattca ctatcataag acattttatt cgaacggtca tctttatccc
     8281 aaagttccat ttgcttataa tcttttagtt cagattcggt taatttgttt aataaataca
     8341 ttttataaaa ttcttcttta cttctgtcat gatttccgcc atggtttatc atattgatat
     8401 attttattaa tttttttcgt tctatatctt caatagtaga gttgtataaa ttgtctatat
     8461 gattcttttc ctttttaaat aaatatccat catcagaaat tccaaattca tactcattat
     8521 tttctatact ttttttcagt agtttaattc gttcttcctc tatctgatca tgaggaattt
     8581 tcactctata cattttttcg gaagactttt tcaacttact catctctaca tcacttaagt
     8641 cattcactaa ctggacaaat ctcaaattat ttaaaatatg aagttcttta ttggattcca
     8701 tgtataattc attcattaaa tggatattag gtccaactgt aaaatcatca actttgtaca
     8761 acaaatctct tttctgttta gctttaccgt catttgtaat aaaaacaact ttttttccca
     8821 ttttcgtata ttcttttgaa tactcaataa tatctttcca tattataaga tcaccatatt
     8881 tcctacaata ttttatatca ccatacattc taagtgaatc gatttcgtct tcttttgaag
     8941 agtcattaaa cccaggggga atattttgct tgtatctctc ctctccctcc ttctctattt
     9001 catctatcca ctcttgacta tatttattac ctactttatt ttcaattaca gaaataagtc
     9061 tttcatataa ttcgttttct tcctccgtaa tcatcgaaga taccttacta tctattactt
     9121 tttttaattc agctaagtaa tcttctgtca ttgttagtag ctcattagta aaaatttctt
     9181 tttcctcttt atctactaaa tcaatttcat tgattttttt atttatattt acaactgatt
     9241 gctctatctc atttttatac tttctaatct ttttaatttt tccttttttc aaactactct
     9301 ttttaaaatt gaactccaga gccactaaat aaggtatata aatattttct tttacttttt
     9361 ccaacgcttc tatgtatttc tttgaaacag ttgtaggtaa ttgaattata tctaaaagat
     9421 aatttgtatc tagtactaat aaattctcac tttcactgct caaatctttc atatctaatt
     9481 tagattgata aaactctgga aaaagctctt tcaaatttgc cattaattat ccctcttatt
     9541 aacaataatt ttatatcttg aatattcttt atacaataat attgtaacat atttattaat
     9601 ataaaataga atacaatagc tttaacatgg ttattctaac ttaaaaaatt tgcaaccaat
     9661 agagttggct taaaaaggta aatcatcatc actaaaactt atttttacta catctactgc
     9721 tcctaaccta gttcttaagt tttctaatat tatttttttc ttttgcttac tactgtatta
     9781 ggaaaaagac ctaacataat atagatgaat accgcttaca aacctacact ttttaactta
     9841 tgaaatgctt ggttctcata aaaaatgata tggttcccta gtattttcct accgaaaaaa
     9901 tccttgtctg actaatgctt gacaaggatt tttttgcaat tctccttata attcgtctgt
     9961 aaaaaatata tcttaagatt taaactgcta gttaaaataa tcaatccatt ccaaaatgtc
    10021 gtatatcaca tagttgatct tgataatcga aaaaaccatt tgaaattatt gtagctggac
    10081 actcccgaaa acacatttct gtaaaaaaac agccttcaca tttttttatg aattttgttg
    10141 aaacatcaat caagctaaat aaatcaacat atttctctga ttgcataata tcagttagta
    10201 gatcaacgtt cacatttcct aaactaaata ctttttctgt ttcaaatttt tggcaaagaa
    10261 atacttcgcc ggtataacta attcgaatct ctagagtagg agtataatta ttttcaaaat
    10321 ataacggaca cctactgttg gaaacatatg gtggtttgat ctcaaaattg tcatcttgca
    10381 attcttccat gagaagcaaa agctctttca ctatacttct aaaaaattct cccgaaacag
    10441 gtttctctcc cttggacctt ccgatattga ttatttcttt aaaagatatc actgaaacat
    10501 ttttagattt aagtgcactt aaaaaaggag ctagcttact cgtatttttc ccagttatca
    10561 caaaatttac gactgtttta attttatatt tttcgaatag ttcaattgcg tagatagctt
    10621 tttgaaaagt accttttccc cttacagcat cgttttcttc tggcgttgtt ccgtcaatac
    10681 taatctgaac ataatctacg acattactca acctctgggc aaggtaatca tctaccatag
    10741 ttccattcgt tactaaccca atgcataaac catatttttg ctttcctatt cttagcaagt
    10801 ttattaaatt tttataaagt aacggctctc ctccagagat aattacattt tgacatttca
    10861 atttcgatat ttctttaaat attgatagaa tctgatcttc gctaaaacga tacattccac
    10921 taccagattt gttgtagcaa tgcttacatt ttagattgca taacgacccc acttctaagt
    10981 atacactcct tagttcaaaa gaattcaagt tcaaatacct ccaaaattaa attggtactc
    11041 atcaacattt tgacttctaa cttctttttt atatgaatta atatgtcgaa atttcaaatt
    11101 tttaatatta ctaatcagac tttgactttc taaattattt tgtatacaga acactttgta
    11161 tgttaacgac ctctgtttta gtagctttgt agtcaaagca atcccatttt ttaaaatttt
    11221 ttcatcgaat acttcaatat ttttatttct gcaataatat tgaagtatta cattgttttt
    11281 attctgaata ttccaaatca tgaacccaca atttgtcttc ctcaagttat ctattatcat
    11341 taaaacaata gtagatttat ttagttcaaa atcacgattt agaatcaaac tatttacaaa
    11401 caaatcatca taaaatggat ttttaaatat tctcaaacaa tccccctttt cttgtaaaat
    11461 aagttttaac aatgatgaat agcaagcact tatatcatag gatatcgaca attcatttga
    11521 taaatgtatg ctttccttca caaaaaaagg attatcttta agttttaaac caccacatat
    11581 tgataacttt tcaatagttt taattacgtc tttttcaatt aaagacttag gggctcctat
    11641 atattttgcc attattttat ctataatatt ttcaacacta ttcactccat cacacattgt
    11701 taaaatataa tagtaagtag agtttactaa ctcagtcttc tgagaattga caatagtttt
    11761 aatcgttaca tacccaccat gttcaaaccg ataatagata agataatttt caatcaaaca
    11821 aggtttaaac tctaaaaatc ttttttgtat taacatttta ccaccctatt ctttacttag
    11881 tttaatatat caaactcggt tgaacggtta ctttgtgtat tattacttgg tgtagtcatc
    11941 tgttttactg atgtaagttt tgaaaccata gatataatat gttctgaacc ccatatttga
    12001 tttagccccc caatccagta ttctgacaga gtgtgctttc tcaaatttcc aaaagtcttt
    12061 ggtaaatata tagatggcgt aattgaccca tccgataata tacaaatagt atccgtatat
    12121 gacgaattag aaaaactctc cgtaaatact aacaagtgat cgattggatc accccaagca
    12181 acattaacat tagttttccc gtttaaattt tccaatattt ttttattgta ttcttttttt
    12241 aactgtctat actctttttc agaaggtaaa atgtgtaaat ttttttcagc tctaccgact
    12301 ggcattaaat cttgtagcct aacttcatgc actcccaact cttctgcaag agaaaagaca
    12361 ctatcaaact cagatatatt ccacttagta ggagaaaaag caataccaga aataatatta
    12421 tatttactta ataactttaa ccctctaatc gctccatcat atgcattttt attattacgc
    12481 aaattattat gtgcccattt ttttccatca agactaattt gtatattatt tatccccttt
    12541 ttctttaatg acttagccaa ctcttctgtt aacaatattc catttgttac catgccacaa
    12601 ctaatattag ctttggtcag tttttctaag actttcaaaa ctaacctttt cctaattaaa
    12661 gtttcaccac cacaaataca tacattgtag ggcttcatct ctatgatttg atcaacaata
    12721 tttaacacct cattatcgga aagttcaaaa gagaaatctc cttccccact actattgtag
    12781 caatgtaggc aatttaaatt acatctattc gtaatatcaa aattaatatt tatcggccct
    12841 ctgactatat tattcatata actactcctt ccatccctat ttataaatta gtcaaagcaa
    12901 taattcatac gtaaataacc tactttcttt ggctaacgta catttattga atcccacagc
    12961 taaaatacga ttttcccaca ctttaaaaaa ttcagtattt gagtctaaat caataactaa
    13021 cttatttact tcttttacta aaaatgatac catttcattt tttatataat ttatcatttc
    13081 ctgtaatttc atttgagagt catttttcaa aaaaataaaa tttatactag ctgaattcct
    13141 ataattattc tcaacaaata atcctataaa gttctctttt gattcatcat aaataacttc
    13201 ttgctctttt ttatacaaat aataccgagc taagctgata ctgttaacct gcattttcat
    13261 aatatttgtg ttatcaaaga aagatgaacc accctcttcg gaaagcgttt tcaaaaaaag
    13321 catcaaatct cctgtatcgc cttcattaac atgtttatac acaatagtca ctccttccaa
    13381 attaaaatag aaaaagtaaa acaatttttt gctttacttt ttctgaaact gagtgctacg
    13441 caatattacc atagcacttg catggcttga acgagtttac aacccagtaa gctgcgacaa
    13501 ctgtaaatac cattacaata ccaaaaactg ttgaacttgt cggttggatt tcagaaccat
    13561 aaaaattttg tgaactggga ctctgatatt ttttttgttc ttctgaaaaa ttttgctcat
    13621 tcatattctc tcctcctttc caatactaat ctatataacc catagtcaac gccatttaca
    13681 cattcctctt gacaatggtc atatttctaa agctatgtgc taagtatacc ataactcctc
    13741 ttgtataaaa aatttttttt atcaataaca aataatttgg tgcttttgat ttaaaatatg
    13801 gtacaatgag ctaaaaggag aaaatcatgt tattatttct aagcaactac tttaaacagg
    13861 caaaaaaaaa gattctaatt tttagcatat taaatatgtt aatcgctttc atatcagctg
    13921 ttgttccgct tatttcgggc aatttcatag attcattagt ttcttcgcat gattatcaaa
    13981 ttataataaa atttatcata atactatgtt tatttgtatt tgcacaattg tcacttggat
    14041 atgttgtcca agttcaagaa gccgttttac aagctcactt gacttataac atacaaaaag
    14101 acattctaaa tcaacttcag aaaactcaaa tttatttaat ttcccaatac gatttagcta
    14161 acttaagtca aagaatatca agtgattctt cttcaatatc atcatttatg atatcttcgg
    14221 gaagttcgtt attagtttgt tgccttaatt tcttcttctc aacaattctt ttatttatcg
    14281 taaaatggga gattgcatta tttattttag tattcttagt attgtatata ctatactttt
    14341 acaaattaca aaataattta acagtgaaac agaaggatgt taaaaatgat tttagctatt
    14401 atttctcaca aatcttttct cagctcaaaa atttaaaaaa tttaaaaatt ttttctttgt
    14461 ataattatta tggaatcagc ttatttgact cctataacaa atatatatat tctttaaaaa
    14521 aatttaaaat cttttctttt aggctcactt caggtgatac cttgttagca ttctttgctc
    14581 aaatagtaat tttcatcttt gggggagtat cagtaataaa tggaaatatg acaattggta
    14641 tattctcagt tttactatca tatttcaata tgatgctcaa ctcaataaaa tatattccat
    14701 cattaacatc gtcctacgcc gaaatgtttg cctcatattc taggattact gaattaatta
    14761 atttagaaaa agataatact ggaaaattaa aatattcaga taataatttt cttgaaataa
    14821 aaaatttaac ctataaatat ccaggctcca acacttattt attttcaaaa tttaattatt
    14881 ctttccaaaa aggcaatatt tattgtttaa agggtaggaa tggtagcgga aaaacaaccc
    14941 tactggatat tatttctaag ctaaaatttt cgtataatgg ttccatagaa ttaaatcagc
    15001 gaaatatcga attattcgat acaaaatatt atcgtgacgt atgtctatca tacatgactc
    15061 aagatgcttt tgttattaaa gctggcttaa aggataacat attatcgcaa aatctctctg
    15121 aaaagttaag tactttaata caagaactcg gcttggaaaa gtatattgat tctaactata
    15181 acataaatac aaaaatttct ggtggagaaa aacagaaaat ctctttctta agaagcatca
    15241 caaaaccatt taatattctc ttgctagatg aaccaacaaa tcacttggat tttataagta
    15301 aggaaatact tatgaagtat ttaaataata taaagaatga tgctattatt attatctcga
    15361 gtcacgataa ttttgtgttg gaacgagtag acaccatcat agatttaaat aaatcctaac
    15421 atggaaagaa ggtaaaagtt aatgttaatt attaacatga taaaatcaac ttatgtaaac
    15481 caaataccta tattgatatt tataattgga ttgattgtat ttgccctgtc aaccaaaacc
    15541 ccgcacggag gaattgcata cagaggatta gcatattaca tatacggaaa acgagtctgg
    15601 tacttttcta ataaattagt aggtactttt ctaatggttg tatcaataat aacccttcta
    15661 tgctttaacg ttttatcaat gtccgaaaac acaaaaataa taattattat cctatcatgt
    15721 ttcatatgcc taattgtttc agatatcgta acaattctat ctataaagaa aggaaggcta
    15781 taataagttc attcttaact ttctttacta ttgatagcct atccactata taataagcat
    15841 ttttatttta atatttccca actttgttta accagtacaa attagttaaa gcctctaact
    15901 tttcttaagt aatgtaacca gttcttactc gattttaaaa ctttaaattg ttaaatatag
    15961 gaggaataaa tgatgaacaa gattcttaaa attttattaa ttatttttgt tattttaata
    16021 gtagtcattt ttctgcctac tattatattt ttcataatta aatagaaagg aggaatttga
    16081 aatgaattgg ttaaatttta gtgaaccttc actgcgtggc aattgttcag gtttaacttg
    16141 cggaattaaa acttgtatct cagtttcttg tccaaataat gggggttgcg catggagatg
    16201 gtgttggaat aaatcttgtt atatcaatct ttaaacaata ggaaaggagc atatgaatat
    16261 gaattggtta aaagactata acgaaattaa acctagaggt gcatgtgtca taagagtttg
    16321 tactcagtat aatggttgta accctctgta ctggtgttgg agattagaag gtaactaact
    16381 gaaagagagg tgttttgtta atgatttggc tttcgcaaaa atcaatagaa cctagatggt
    16441 gtttcttccg taccgcatgt cctagaaaac aaaatgatac ttgtataatt catataactt
    16501 aaatgggaat tgtgttgttc atagtttgaa tagtaacaat atgtttttaa tcacaaaccc
    16561 ttaatacaag tccgaatgaa aagtttcttt ataatcaact aatttttggt gataaaatta
    16621 agtttctacg aaataattat tatgtaatta ttggaaaagc cctattacca aaatcattac
    16681 tgatgttgaa atattttatt ttataaaacc taaatatcta aagacttatt taaccttagt
    16741 tgataatatt ctaaatgaac atgcctattt taaattactt tacatctgca taaatatcac
    16801 ctctcctatt accaaagttg ttggcttttg ggagggaata acaatcaacc cgctagaaaa
    16861 cctataaatt aggttttcta gcgggttttc ttttgtgtta tcacactttc ctcccaccat
    16921 tctccgtttt tcctttgctc caccgccctc aaagtcctat aatttaatca taagaataat
    16981 ggctattaat aaaatttatc aataaaaagg aagcgatttc aacatgtcaa aagaaacttt
    17041 tcttaagtat ggttttgttg tcctcttcat aggaattttt ttacttcgtg cccaaaaatt
    17101 tatttctgag cccctttcgt accttttttc gggtattctt ttgcttattg ttgcgtattt
    17161 aatactcgtg aaaaaaatga actttttctc aagtttgctc acaattaccg accagccttc
    17221 ttctacccaa caacgattag gtcaactttc tggtcttgtc agtttattga ttggtttact
    17281 tctggtaatt cttagcttca ttttctttct ccaactttga ttcccccttg actctccctt
    17341 cactcttggc tatgattacc ttagcaagta caatggtgta ctgtgaacag tcgagcaacg
    17401 gcgctcaaaa agattggctt tcgtgcattc tttttgaggg ctttttattt ttagaaagta
    17461 gggaaattga atggaaaaaa tgtaccgcag tccgtatgaa gcgtacccgt atctatcttc
    17521 taaaccagaa gatttacgat gtgattttga attaatgact gatgaattgg cctcgatgac
    17581 aggtcttcta cgaggatatg tgcaacaatt agacgtccct gaacagcctg cactaacaga
    17641 agaactagcc aaaatttgcg agttaatcta ccatgtcaat ccaacgaccc gaacaaaatt
    17701 aacagtcaca gaggacgaaa tagcctggct tttggaacgt gtcaatgcta tgaatgaact
    17761 gacatacgaa gaaaatcgtc cttttgtttt accgatgggc acaatctgtt cctcttatgc
    17821 acacatttta agagccaaag ccaaagatat tgttcgttta ctttatcgca tggactatgg
    17881 tggtaaaaaa attgatccgc agctgtatga tgtagtcaac ttactctcag gttacttttt
    17941 catgttagct ttgtatctaa atcagctcga aaatggtgaa gaagttccct ttgtttctcg
    18001 caactattct atttaatttg gaggaagatg atgaattcat tgccaatact tgaaaaagca
    18061 gtgggcacga ttaccctgct ttccgaagaa aaacaaaatg ccgaatatga aggcttttta
    18121 tgccaagtta atgaatcgca acaacttatc cgcagtcgct tagccaaaaa aacgccgaaa
    18181 aaagaaggct attttgtagc cttctgggaa aaaaatcaac aaaatcagaa cgaagccttt
    18241 gatgcaacgg aagcccctga aatgttagca attgtcattg ctgatcaaga aaagcaaggt
    18301 ctctttcttc tgccaaaaga atgtttaatc caacaaaaaa ttctcaaaac gcatcaacaa
    18361 aaaggcaaaa tggcggcccg tttttatcct tcttggtgcc aaaaccttaa tcaaaccgcg
    18421 aaaaaaacac aaaaatggca actaacttac tttactgatt tatctaaata ctaaaaacgt
    18481 cagctggctt cagaagccag ctgacgtttg tttattttac tgtttagcca attggtggcg
    18541 taccttctgc gttcccagca atcgcttcga tttgaatctg ggcacctttt ggtaaatccg
    18601 tcacaccaat cactcttctg gcaggcgtgc cttcaggaaa gtacgtttgg tagacgtcat
    18661 ccactgccgc cagctcttca atctctttca caaaaatatt cactttcacc agatcagcta
    18721 agctgtgatc cacactttca ataatcgctt tgatgttttc taaacattgc gtcgtttgtt
    18781 ccttgattcc gccagcgact aacgcatttg ttttagggtc caatggtagc tgagctgata
    18841 gatggttgta atgagaaaaa gcaacagttt gtgtcgaaaa tggacacttc ggtgcgtgat
    18901 ctgtattatt tgcttcaata attaatccat gtcgatcttc aatcgcttgt ggtggcgtac
    18961 catccccatg agaaaccacc gcttctactt gaaccgccgc gcccattggt aaatcagcaa
    19021 cagcaatcac tgttcgtgct ggcatgtaat tgaccgtacg cgcaattcct gaatctggga
    19081 aaaaagcggc atatacttga ttgacagctt ccagcttaga taaatctttt aaataaatgt
    19141 tgaccttcac aatatcatca aaaggcacat caatactggt taaaatggct tttatgtttt
    19201 tcaaacattg ttttgtttgc gttttaacac agccagccac aactctgccc gtttgaggat
    19261 ctataggcaa ttgtgcagac agattgttat aatgagaaaa cgcgaccgtt tgactggcta
    19321 gagcatcaat tggtgcctga acagtctgat ttgttaattt aattaaatcc ccagcttgag
    19381 gtgcattagg gatagttcct tccccatttg aaacaagtgc ctccatttga acagaagcgc
    19441 ctaacggcaa atctgcgacg gcaaccactg ttttagctgg ataataatgg gtaaaaaagg
    19501 ccgcatagac ctcctcaact gcggtaacat cccgcatatc tttgacaaaa atggtcattc
    19561 tgacaatgtc actcatcaca tggttgatac tttcaacaac cgcttggata tttttcaaac
    19621 attgtgtcgc ttgggcccga atgccacctt ctaccaattg tccagaggtt ggctcaatag
    19681 gtaactgtgc cgacaaatga ttatagtggg aaaatgcgac tgtttgggct gcgagaggat
    19741 gctttggtgc acgttctgta tttcttgcta agacgatatt ttcattactc ataactctac
    19801 tccctttttt agcattccaa caaaaatgat tccgcttaca ttttcaagca ttaaacttcc
    19861 aacaagatcc tttttatttt cttgcttttc tattaatggt gatagctttc caccaccact
    19921 tctttcagtc tacaataaga acaggaacat ttcaataagg cattcctaaa ttgattgttg
    19981 gccctcaaac aaatcttctt ccgttaaaga aggctgaggt cgggaaagaa ccgtttagct
    20041 ccgagaaata agaagaaatt tccgaaaatt gctctttaat ttttggagaa tttcggctta
    20101 tttccgaagg agttggttct gttcccgccg tttatcaggt tttgatcctg ggacaaaaat
    20161 ccaaagtgat ttttgtccca ggatcagtct ttatagataa ctcgttagct ttaactagtt
    20221 ttatttaacc accatatact cacgataatt ttccgagaac gtatccatta gcgtataaat
    20281 tcgttcaaaa tcatagtcac gacgagggtc atcataccaa acacattgaa tacttccaat
    20341 aattgtaaga tttgggctac ctgctggcac atctgtaaat gcttttttcg acatatttgc
    20401 taaagcatca tcatattgat aaatgccaga atcaacattg ccagctaccc aataccacgc
    20461 atcattggta ttaaaaattt tgtgtccttt ttgaacaaag tactcaggtt tggctacgtc
    20521 atacccactc caaccggctg tccaataaga aataataatc tctgggtcaa atgtaccgaa
    20581 agaatcgtcg ctgttgtaat aaatgccatc attgaagctc attggctgca tgcccgcatc
    20641 tttaattatt ttagctaaat cattcgcata agcgacaaaa tccttgtagc gcccagaaga
    20701 ttgcagtttc gcccaaccgc ccgtgtcgac atcatttgca tactcatcgc cgccaaaatt
    20761 gaaaatttca ctatgcgtgg aaaaataagc cacgtactta ctgataatcg cctttgtgaa
    20821 attcactgcc ttttggttcc ctaaatctac tgttcgtttt gagccatcaa aagcgggatt
    20881 tttaatcgct agtttttcca tggccactaa caaggcatcc atatgtcctg gactgttaat
    20941 cacgggaatg atgttgatgt tgcgcgcttt cgcaaaagcc aacaaccgat ccatttcttt
    21001 ttgtgtta
//
