LOCUS       NZ_CP036170            20885 bp    DNA     circular CON 15-DEC-2024
DEFINITION  [Clostridium] scindens ATCC 35704 chromosome, complete genome.
ACCESSION   NZ_CP036170
VERSION     NZ_CP036170.1
KEYWORDS    RefSeq.
SOURCE      [Clostridium] scindens ATCC 35704
  ORGANISM  [Clostridium] scindens ATCC 35704
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae.
REFERENCE   1  (bases 1 to 3658040)
  AUTHORS   Devendran,S., Shrestha,R., Alves,J.M.P., Wolf,P.G., Ly,L.,
            Hernandez,A.G., Mendez-Garcia,C., Inboden,A., Wiley,J., Paul,O.,
            Allen,A., Springer,E., Wright,C.L., Fields,C.J., Daniel,S.L. and
            Ridlon,J.M.
  TITLE     Clostridium scindens ATCC 35704: Integration of Nutritional
            Requirements, the Complete Genome Sequence, and Global
            Transcriptional Responses to Bile Acids
  JOURNAL   Appl Environ Microbiol 85 (7), e00052-19 (2019)
   PUBMED   30737348
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3658040)
  AUTHORS   Devendran,S. and Ridlon,J.M.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-FEB-2019) Dept. of Parasitology, University of Sao
            Paulo, Av. Prof. Lineu Prestes, 1374, Sao Paulo, SP 05508000, Brazil
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu v. 1.5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 300x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004295125.1-RS_2024_12_13
            Annotation Date                   :: 12/13/2024 14:32:22
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,771
            CDSs (total)                      :: 3,697
            Genes (coding)                    :: 3,591
            CDSs (with protein)               :: 3,591
            Genes (RNA)                       :: 74
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 30 of 106
            Pseudo Genes (incomplete)         :: 86 of 106
            Pseudo Genes (internal stop)      :: 13 of 106
            Pseudo Genes (multiple problems)  :: 19 of 106
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:01:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3028543
            Orig. end                         :: 3049428
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP036170.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20885
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="2"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20885
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20885
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10885](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10885)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(757..2193)
                     /db_xref="GeneID:62697286"
                     /gene="glgA"
                     /locus_tag="HDCHBGLK_RS15600"
                     /old_locus_tag="HDCHBGLK_03100"
     CDS             complement(757..2193)
                     /EC_number="2.4.1.21"
                     /GO_function="GO:0004373 - alpha-1,4-glucan
                     glucosyltransferase (UDP-glucose donor) activity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:62697286"
                     /gene="glgA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009248492.1"
                     /locus_tag="HDCHBGLK_RS15600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_03100"
                     /product="glycogen synthase GlgA"
                     /protein_id="WP_009248492.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 5.1e-14,
                     bitscore: 50.0, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKILFAASEAVPFIKTGGLADVVGSLPKYFDKEKYDVRVMLPKY
                     MCMKEEWKEKLSYHTHFYMDLNWRKQYVGILELEYDGITFYFIDNEYYFNGFAPYGDMY
                     ADIEKFAFFSKAVLSALPVIGFRPDIIHCHDWQAGLIPVYLDNFRYGDEYYRGIKTIMT
                     IHNLKFQGTWDTKRVRDITGLPQYYFAPDKLEAYKDANYLKGGIVYADRITTVSNSYAE
                     EIKTPFYGEKLEGLMNARSNCLSGIVNGIDYEDYDPATDTHIEKNYTCDSFRREKIKNK
                     IALQKELNLEQDHHIIMLGIVSRLTDQKGFDLIAYVMDELCQDAVQIVALGTGDEKYEN
                     MFRHFAWKYPGKVSANIYYSEALSHKIYASCDAFLMPSLFEPCGLSQLMSLRYGTVPIV
                     RETGGLKDTVEPYNEYEKTGTGFSFMNYNAHEMLATIRYAERIYYDKKRDWNKIVERGM
                     NQDFSWKNSAKQYEELYDGI"
     gene            complement(2258..3049)
                     /db_xref="GeneID:62697287"
                     /gene="spo0A"
                     /locus_tag="HDCHBGLK_RS15605"
                     /old_locus_tag="HDCHBGLK_03101"
     CDS             complement(2258..3049)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0005509 - calcium ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0042173 - regulation of sporulation
                     resulting in formation of a cellular spore [Evidence IEA]"
                     /GO_process="GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /GO_process="GO:0051606 - detection of stimulus [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:62697287"
                     /gene="spo0A"
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004605987.1"
                     /locus_tag="HDCHBGLK_RS15605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_03101"
                     /product="sporulation transcription factor Spo0A"
                     /protein_id="WP_004605987.1"
                     /transl_table=11
                     /translation="MGEINVAIADDNERILDLLGEIISSDKELNLVGKANNGEDAYHLI
                     KEKQPDVVLLDLIMPKMDGLSVMEMVGGDKDLKKQPDFIVVTAVGQERITEDAFRKGAS
                     YYIMKPFNNEMVLNRIKNANHLIRHEMKTQSAQGLKMEEAPEVNLENRVTDMIHEIGIP
                     AHIKGYHYLRDAIIMAVEDMDVLNAITKVLYPTVAKMHQTTASRVERAIRHAIEVAWSR
                     GKLDTLDDLFGYTVSNGKGKPTNSEFIALIADTIRLEYKNR"
     gene            complement(3163..4233)
                     /db_xref="GeneID:62697288"
                     /gene="spoIVB"
                     /locus_tag="HDCHBGLK_RS15610"
                     /old_locus_tag="HDCHBGLK_03102"
     CDS             complement(3163..4233)
                     /EC_number="3.4.21.116"
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:62697288"
                     /gene="spoIVB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004605986.1"
                     /locus_tag="HDCHBGLK_RS15610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_03102"
                     /product="SpoIVB peptidase"
                     /protein_id="WP_004605986.1"
                     /transl_table=11
                     /translation="MRKYWYRRILIMIVTFTVAVGGGYYLIEAKHSQLRQEVSAGTSSR
                     NMVIPGGMPIGIYLETQGVMVLGTDAVTAMDGMEYEPASHLVKAGDYIVGLDEEEISSK
                     SQLVDAMKKIDKDEVVLKVRRSEDLIDIKLKPVRCSSKDYKLGIWVRDNAQGLGTITFL
                     NADSQFGALGHGIHDVDTNTLLEINDGTVYETSIKDIQKGVNGTPGGMEGIIVYNNYNV
                     LGSITKNTDCGIFGKIDRIDALFTDQTPMETASTDEIEEGPATIRCAVEGEVKDYEIHI
                     TKVDKHTDELNKGLVIEVTDKKLLEVTGGIVQGMSGSPIMQNGKIVGAVTHVFVQDSTK
                     GYGIFIENMLKNVTLS"
     gene            complement(4319..5992)
                     /db_xref="GeneID:62697289"
                     /gene="recN"
                     /locus_tag="HDCHBGLK_RS15615"
                     /old_locus_tag="HDCHBGLK_03103"
     CDS             complement(4319..5992)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:62697289"
                     /gene="recN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004605985.1"
                     /locus_tag="HDCHBGLK_RS15615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_03103"
                     /product="DNA repair protein RecN"
                     /protein_id="WP_004605985.1"
                     /transl_table=11
                     /translation="MLQNLHVKNLALIDEIEVEFKDGLNILTGETGAGKSIILGSISLA
                     LGGRYTKDILRQGAEYGFVELTFLVENESQQKKLKEMDIYPEEGMVTLSRRLMAGRSVS
                     RINGETVQMGLLKEVSSILIDIHGQHEHQSLLYKKNHLGIVDAFAREYLAEDKKKAAQA
                     YKAYKACEKELKEAMADESQRAKELSFLKFEVSEIQEAHLLPGEDEELESLYRRMTNSK
                     KIADSVNEAYLYTSEGGGNASEALSRAIRALSEASEYDDRAAQLYDQLVEVDSLLNDFN
                     RELADYSKTCEFSDEEFYETENRLNEINHLKTKYGDTVEKILDYCASQEERIGILEDYD
                     NYILRLKDQCAKAEEALRQSTARLTKIRKKQAKILEQAIEEGLKDLNFENVKFRIQFES
                     TKDYTAEGMDDIEFMISLNPGQPVKPLAGVASGGELSRIMLAIKAVMAKRDEIETLIFD
                     EIDVGISGRTAQKVSEKMAFIGTKHQVICITHLAQIAAMADHHYMIEKSTKKGDTKTSI
                     ELLDEKRSIEELARILGGARITDTVVQSAVEMKELAKQTK"
     gene            complement(6001..6450)
                     /db_xref="GeneID:62697290"
                     /gene="argR"
                     /locus_tag="HDCHBGLK_RS15620"
                     /old_locus_tag="HDCHBGLK_03104"
     CDS             complement(6001..6450)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:62697290"
                     /gene="argR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004605984.1"
                     /locus_tag="HDCHBGLK_RS15620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_03104"
                     /product="arginine repressor"
                     /protein_id="WP_004605984.1"
                     /transl_table=11
                     /translation="MKVNRHAKIIELINKHHIETQEELAEYLNQEGFKVTQATVSRDIR
                     DLKLTKVPYENGKQRYAVHQSAENGMSEKYIRVLRDGYVSMDMAQNILVIKTVAGMAMA
                     VCAAIDAMQWNEVVGSIAGDDTIMCAIRSVDDTVKVMDKISKIVL"
     gene            complement(6455..7288)
                     /db_xref="GeneID:62697291"
                     /locus_tag="HDCHBGLK_RS15625"
                     /old_locus_tag="HDCHBGLK_03105"
     CDS             complement(6455..7288)
                     /codon_start=1
                     /db_xref="GeneID:62697291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009261763.1"
                     /locus_tag="HDCHBGLK_RS15625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_03105"
                     /product="NAD(+)/NADH kinase"
                     /protein_id="WP_039909557.1"
                     /transl_table=11
                     /translation="MDRFLIVTNDGKDVDHIITRKVKGLLETEGKKCVLCQKDEKKNII
                     KESIPEDIECAIVIGGDGSLIEVARLLWERDVPILGINMGTLGYLTEVEVGNIEEAIGQ
                     IVSNDYTFEDRMMLEGIFEDGSKDVSLNDIVISRKGELRVIHFQLYVNGELLNSYEADG
                     IIISTPTGSTAYNLSAGGPIVEPTASLIVITPICSHALNTSSIVLSSDDEIGIEIGMGR
                     HESKEEVFTTFDGADTVVLTTGDKVTVRRSEASTKIMKLSKVSFLETLRRKMKGN"
     gene            complement(7306..8115)
                     /db_xref="GeneID:62697292"
                     /locus_tag="HDCHBGLK_RS15630"
                     /old_locus_tag="HDCHBGLK_03106"
     CDS             complement(7306..8115)
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:62697292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009248490.1"
                     /locus_tag="HDCHBGLK_RS15630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_03106"
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="WP_004605982.1"
                     /transl_table=11
                     /translation="MKERLDILLVKRNLAASREKAKAIIMSGSVFVDGQREDKAGATFP
                     EKAAIEVRGHTLPYVSRGGLKLEKALRNFDVTVDGKVCTDVGSSTGGFTDCMLQNGARK
                     VYAIDVGRGQLDWKLRQDERVVCMEKTNIRYVTPEDIGEPVDFSSIDVSFISLTKVLLP
                     IHNYLKDKGQIVALIKPQFEAGREKVGKKGVVRDKRTHMEVISMVIQYALSIGFSILNL
                     EFSPIKGPEGNIEYLIHLEKCGEDARIAEGIEEEKTVEEAFCTLAKN"
     gene            complement(8124..9986)
                     /db_xref="GeneID:62697293"
                     /gene="dxs"
                     /locus_tag="HDCHBGLK_RS15635"
                     /old_locus_tag="HDCHBGLK_03107"
     CDS             complement(8124..9986)
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:62697293"
                     /gene="dxs"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004605981.1"
                     /locus_tag="HDCHBGLK_RS15635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_03107"
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_004605981.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 5.3e-119,
                     bitscore: 394.2, seeds: 174, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLERIQKENDIKELNLEELEELALEIREFLVEKISKTGGHLASNL
                     GVVELTMAMHLMFHLPEDKIIWDVGHQAYTHKLLTGRKAGFDELRKYGGMSGFPKRKES
                     ACDAFDTGHSSTSISAGLGYVQARDLKGEDYSVVSVIGDGSLTGGMAYEALNNASSLKT
                     NFIIVLNDNHMSISENVGGMSKYLAELRTADIYTGLKKGVTNALEKVPLVGDSLIEHIR
                     RTKSSIKQLVVPGMFFEDMGITYLGPVPGHNIGLLCKAFKEARKINGPVLLHVMTKKGK
                     GYEPAELKPDKFHGVGPFQVETGELETPKDKDTYTDVFGKVLCDEAGRNPDVVAITAAM
                     ADGTGLTRFRQMYPNRFFDVGIAEEHGVTFAAGLSAGGMKPVFAVYSSFLQRAYDQLIH
                     DVALQNLPVVLAIDRAGLVGSDGETHQGIFDLSYLSSIPNMVVMTPKHKWELADMLRFA
                     LSYDGPVAIRYPRGSAFDAYRQFRAPVVYGKSEMLYEEKDIAILSVGHMFESALQARER
                     LKESGYSCTLVNARFVKPIDEAIIASLCRNHRLIVTVEENVQTGGYGEHVLEYACRKDL
                     GVKVLTLALPDDYVEHGNIGVLRKETGIDVESIIRRIKDAYGKL"
     misc_feature    9952..9966
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 20.67"
                     /tool="antismash"
     gene            complement(10001..10885)
                     /db_xref="GeneID:62697294"
                     /locus_tag="HDCHBGLK_RS15640"
                     /old_locus_tag="HDCHBGLK_03108"
     CDS             complement(10001..10885)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:62697294"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004605980.1"
                     /locus_tag="HDCHBGLK_RS15640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_03108"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_050755135.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4.6e-54, bitscore:
                     181.2, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQAQMKHKVEKIEGILTEYLPRQEGFQSIIMEAMNYSLLAGGKRL
                     RPMLMNETYRLFGGESPLIRPFMAAIEMIHTYSLVHDDLPAMDNDEYRRGRKTTHIVYG
                     EDMGILAGDALLNYAFETAFKAFVMEPEESLLIGRALGVLGEKAGIYGMIGGQVIDVKE
                     TGHSIPKEVLDTIYELKTSALIEASMMVGAILGGASEEEVKIIEKIARYVGIAFQIQDD
                     ILDVTSTKEVLGKPTHSDEKNEKTTYVTLMGTAEAGRMVEELSDQAVSLLHQLSEENEF
                     LEQLLLQLIHREK"
     gene            complement(10935..11159)
                     /db_xref="GeneID:62697295"
                     /gene="xseB"
                     /locus_tag="HDCHBGLK_RS15645"
                     /old_locus_tag="HDCHBGLK_03109"
     CDS             complement(10935..11159)
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:62697295"
                     /gene="xseB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004605979.1"
                     /locus_tag="HDCHBGLK_RS15645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_03109"
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_004605979.1"
                     /transl_table=11
                     /translation="MDKDKKIQENATLEELFVQLEDAIRKMEKEDISLEDSFSLYHKGM
                     DMLKLCNEKIDKVEKKMLVLDEEGDAHEF"
     gene            complement(11152..12363)
                     /db_xref="GeneID:62697296"
                     /gene="xseA"
                     /locus_tag="HDCHBGLK_RS15650"
                     /old_locus_tag="HDCHBGLK_03110"
     CDS             complement(11152..12363)
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:62697296"
                     /gene="xseA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009248488.1"
                     /locus_tag="HDCHBGLK_RS15650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_03110"
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="WP_004605978.1"
                     /transl_table=11
                     /translation="MTRNVYTVKQVNAYIKNMFTQDYMLNRIYVKGEVSNCKYHTSGHI
                     YFSLKDESGTIACVMFAGQRGGLSFRMSEGQQIVVLGSVNVYERSGSYQLYAKEIRLDG
                     DGLLYERFQMLKKELEEMGMFAPEYKKPIPSFASRIGVVTAPTGAAVRDIMNIAGRRNP
                     YVQLILYPAQVQGEGAKESIVRGIRMLEAYGVDVMIVGRGGGSIEDLWAFNEEEVARAI
                     FECSVPVISAVGHETDTTIADYAADLRAPTPSAAAELAVYDYRQVQMGMQEYRLRMNRL
                     LNQKIQVARLKLREYHTRLKYLHPRLKLQEQQQRLSEMEDRMKMLMEGKVRDARHRMAL
                     YVEVMKGLSPLQKLSHGYAYVEGRDKKAIKSIRQVRNQDRLSIYVTDGILQATVEDVKE
                     EQHG"
     gene            complement(12377..12775)
                     /db_xref="GeneID:62697297"
                     /gene="nusB"
                     /locus_tag="HDCHBGLK_RS15655"
                     /old_locus_tag="HDCHBGLK_03111"
     CDS             complement(12377..12775)
                     /GO_process="GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:62697297"
                     /gene="nusB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004605977.1"
                     /locus_tag="HDCHBGLK_RS15655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_03111"
                     /product="transcription antitermination factor NusB"
                     /protein_id="WP_004605977.1"
                     /transl_table=11
                     /translation="MKRTEQREHIFKMLFGVEFNAGGDMPEQLELYFGQLEGAGEKDLD
                     YIREKVQKIASKVEEIDALINEHTTRWKTSRMNKVDLTILRLAVYEMRWDEDVPTGVAI
                     DEAVELAKKYSSEDGPSFVNGVLAKLVD"
     gene            complement(12776..13159)
                     /db_xref="GeneID:62697298"
                     /locus_tag="HDCHBGLK_RS15660"
                     /old_locus_tag="HDCHBGLK_03112"
     CDS             complement(12776..13159)
                     /codon_start=1
                     /db_xref="GeneID:62697298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006427558.1"
                     /locus_tag="HDCHBGLK_RS15660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_03112"
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="WP_004605976.1"
                     /transl_table=11
                     /translation="MSREERNTYTIKGDENLGEVKIADEVVAIIAGLAAMEVDGVSSMA
                     GNATRELIGKLGMKSLSKGVKVDVLDGIVTVSLALNLKYGYSIKEITTKVQEKVKAAIE
                     NMTGLDVADVNIRIAGVDVPEEA"
     misc_feature    complement(13188..13201)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 21.98"
                     /tool="antismash"
     gene            complement(13228..14829)
                     /db_xref="GeneID:62697299"
                     /locus_tag="HDCHBGLK_RS15665"
                     /old_locus_tag="HDCHBGLK_03113"
     CDS             complement(13228..14829)
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_process="GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:62697299"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190: GTP-binding protein LepA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004605975.1"
                     /locus_tag="HDCHBGLK_RS15665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_03113"
                     /product="peptide chain release factor 3"
                     /protein_id="WP_004605975.1"
                     /transl_table=11
                     /translation="MSQINNQVKEQIKKRRTFAIISHPDAGKTTLTEKFLLYGGAINQA
                     GSVKGKATAKHAVSDWMEIEKERGISVTSSVLQFNFDGYCINILDTPGHQDFSEDTYRT
                     LMAADSAVMVIDASKGVEAQTRKLFKVCTMRHIPIFTFINKMDREAMDTFELLDDIENE
                     LGIATCPINWPIGSGKEFKGVYDRETKKVELFSDTRKGTTQGEVKKVDIADPEIAWLIR
                     DSQRVQLEEEIELQDGAGAQFDQELVSKGELSPVFFGSALTNFGVETFLKHFLKMTSSP
                     LPRKSDRGLIDPMEEGDFSAFVFKIQANMNKAHRDRIAFMRICSGEFEAGMDVFHIQGG
                     KKVRLSQPQQMMASERKMIEKAYGGDIIGVFDPGIFSIGDTLTNAGDKFVYEGIPTFAP
                     EHFARVRQVDTMKRKQFIKGINQIAQEGAIQIFQEYNTGMEEIIVGVVGVLQFDVLKYR
                     LENEYNVEIRMDTLPYEHIRWIENTEIDLDKLTGTSDMKKVKDLKGRPLLLFINEWSIR
                     MTIERNDGLELSEFGR"
     gene            complement(15210..15845)
                     /db_xref="GeneID:62697300"
                     /locus_tag="HDCHBGLK_RS15670"
                     /old_locus_tag="HDCHBGLK_03114"
     CDS             complement(15210..15845)
                     /codon_start=1
                     /db_xref="GeneID:62697300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004605974.1"
                     /locus_tag="HDCHBGLK_RS15670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_03114"
                     /product="SpoIIIAH-like family protein"
                     /protein_id="WP_004605974.1"
                     /transl_table=11
                     /translation="MKRIFKKNQIIIAALAVMIAAAGYLNYSGKLFGDKDTAEKTNAEL
                     ANKELLDISEEDVTTSASDDIKSQDGTDSDGSVDGTPGEAVLTSGEASAVVAEAKVTRE
                     QVRAKNKESLMEIIDNENLSDEQKQDAVNQMVAMTDIAEKEAAAETLLASKGFSEAVVS
                     LTQDAADVVVNAAELSDANRAQIEDIITRKTGVAAQNIVITPVYSEGK"
     gene            complement(15874..16476)
                     /db_xref="GeneID:62697301"
                     /locus_tag="HDCHBGLK_RS15675"
                     /old_locus_tag="HDCHBGLK_03115"
     CDS             complement(15874..16476)
                     /codon_start=1
                     /db_xref="GeneID:62697301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004605973.1"
                     /locus_tag="HDCHBGLK_RS15675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_03115"
                     /product="hypothetical protein"
                     /protein_id="WP_004605973.1"
                     /transl_table=11
                     /translation="MDVKKKKRFEIPKNFSIKKLKKDQLLILLLVGILLVVIAIPTGKG
                     KDAASKDAGSSTAAEGGGEAAYGNYASYMEGHLEGVLSQMAGVGDVTVMITLKSSAEKV
                     VEKDVEAQSETVTESDSQGGTRTTQNSSHGESTVYDGDGSQGQAPYISKELSPQVEGVV
                     VIASGGDNAVVKQNITEAVQALFGIDTHKIRIMKKNS"
     gene            complement(16466..16816)
                     /db_xref="GeneID:62697302"
                     /locus_tag="HDCHBGLK_RS15680"
                     /old_locus_tag="HDCHBGLK_03116"
     CDS             complement(16466..16816)
                     /codon_start=1
                     /db_xref="GeneID:62697302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004605972.1"
                     /locus_tag="HDCHBGLK_RS15680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_03116"
                     /product="stage III sporulation protein AF"
                     /protein_id="WP_004605972.1"
                     /transl_table=11
                     /translation="MFEYLYEWMKNIAFYMVLITAVIHILPNSDYKKYIRFFTGMVLVV
                     MLATPLLKIFGMEHPLGSLYDSKEYQEQMKKIEEESKYLGETLPEGYPDDAGQEPEDEE
                     TGIEVEEIEIGR"
     gene            complement(16826..18010)
                     /db_xref="GeneID:62697303"
                     /locus_tag="HDCHBGLK_RS15685"
                     /old_locus_tag="HDCHBGLK_03117"
     CDS             complement(16826..18010)
                     /codon_start=1
                     /db_xref="GeneID:62697303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004605971.1"
                     /locus_tag="HDCHBGLK_RS15685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_03117"
                     /product="stage III sporulation protein AE"
                     /protein_id="WP_004605971.1"
                     /transl_table=11
                     /translation="MRRRKMVQAAILWVILLLIFSPLPAQAKEARQSGTNEDKAESSGM
                     QEDLIGEFDFGEIDDSLKELFPEEKLDFKETLMGVISGDLTFSAQLLNRLVSDQLGYAF
                     RSCKDNLVHILLIAVIAAVFSNFSNVFQSRQISEISFYALYLLLIALALSSFQVVVEWV
                     GQGIDSLTSFMGVFCPLYFLAVAIAKGSVTSIAFYNLVLFLIFLVELLITSFLLPVIHI
                     YMMVRVLNYLSSEEYLSKFAELIQVSVSWILKTLLACIIGLNVIQGMISPAIDSVKRSA
                     IARGAEAIPGIGDAIGGVAEVALGTAVLVKNGIGMTGALICIALCVVPLAQIACIAFLY
                     KLAAAIIQPVSDKRIVGCVETVGDGCQLLMRVVFTTGLLFLLTIAIVSAVTSNV"
     gene            complement(18007..18393)
                     /db_xref="GeneID:62697304"
                     /locus_tag="HDCHBGLK_RS15690"
                     /old_locus_tag="HDCHBGLK_03118"
     CDS             complement(18007..18393)
                     /codon_start=1
                     /db_xref="GeneID:62697304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008975813.1"
                     /locus_tag="HDCHBGLK_RS15690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_03118"
                     /product="SpoIIIAC/SpoIIIAD family protein"
                     /protein_id="WP_009248485.1"
                     /transl_table=11
                     /translation="MNMIQIGIIGVAGTLLAVQFKSGKSEYGIYISVALSLVIFFAIIG
                     RLEVIIDALRTIANYINMDTAYIGTLIKMLGITYVAEFSAGICKDAGYQTIALQIEIFG
                     KLAVLVLSMPVLMALLNTIKDFLS"
     gene            complement(18409..18603)
                     /db_xref="GeneID:62697305"
                     /gene="spoIIIAC"
                     /locus_tag="HDCHBGLK_RS15695"
                     /old_locus_tag="HDCHBGLK_03119"
     CDS             complement(18409..18603)
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:62697305"
                     /gene="spoIIIAC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006779097.1"
                     /locus_tag="HDCHBGLK_RS15695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_03119"
                     /product="stage III sporulation protein AC"
                     /protein_id="WP_004605969.1"
                     /transl_table=11
                     /translation="MSVNLIFKIAAVGILVSVLSQVLKHSGREEQAFLTSLAGLLLVLF
                     WIVPYIYDLFESIQHLFSL"
     gene            complement(18615..19142)
                     /db_xref="GeneID:62697306"
                     /locus_tag="HDCHBGLK_RS15700"
                     /old_locus_tag="HDCHBGLK_03120"
     CDS             complement(18615..19142)
                     /codon_start=1
                     /db_xref="GeneID:62697306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004605968.1"
                     /locus_tag="HDCHBGLK_RS15700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_03120"
                     /product="stage III sporulation protein AB"
                     /protein_id="WP_004605968.1"
                     /transl_table=11
                     /translation="MTAMVKTFGAVLIIGATSLWGIRAADRINDQYVQMQYLKKLIYQL
                     RSEIRYARSYLGEAFRHIGTSSREPYKGWILEIYDRLEHKNRGTLADIWEDTVREYLGA
                     SGLPDEELDKLINLGGQLGVADIEMQVKTLDLYLEEMSLSMEEMRGGMKAKVRLCHCLG
                     VMSGIFITVLLI"
     gene            complement(19139..20077)
                     /db_xref="GeneID:62697307"
                     /gene="spoIIIAA"
                     /locus_tag="HDCHBGLK_RS15705"
                     /old_locus_tag="HDCHBGLK_03121"
     CDS             complement(19139..20077)
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:62697307"
                     /gene="spoIIIAA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004605967.1"
                     /locus_tag="HDCHBGLK_RS15705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_03121"
                     /product="stage III sporulation protein AA"
                     /protein_id="WP_004605967.1"
                     /transl_table=11
                     /translation="MQENRILNVLPRSVRILIHKEQLQYEHLQEIKLRVEKPLLLIYRG
                     EELILGGQRGKPYMVTKEDVREMLEYISNYSLYAYEQEMKQGFITIEGGHRVGMTGQAI
                     IENGKVKNLKHISSVNVRMSHEVLGCADKVFPHITYNRSLYHTLVISPPRCGKTTLLRD
                     MIRQISDGNDWVRGMAVGVVDERSEIGGCYMGVAQNHLGIRTDVLDGCPKAEGMIMLIR
                     SMGPEVIAVDEIGSAEDVHAIEYAMHCGCKMLATVHAGSMEELRKKPLLDRMIDQGRFE
                     RYILLGNRAHVGQIDGIFDHRGSLLYREDVR"
     misc_feature    complement(20250..20267)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 22.53"
                     /tool="antismash"
ORIGIN
        1 gatcctcccc gaagcggtcc aggatcgcgc ggaatctctc aggcaggacg gtaccggaca
       61 gatcgcagat gcgcttcatc tgctttgcac tggtaaccgg catgatgcct ggaagcaccg
      121 gaaccgtgat ccctttttcc cggatccggt ataagaaatt atacaggata ttattgtcga
      181 aaaacatctg tgtcgtgagg aaatccaccc cgcagtccac cttgtgcttc agattcataa
      241 tatcgtcttt cttatgagcc gcctcaacat gtccttccgg atagcatgcc gctccaatgc
      301 agaaatcccc ctggctctta atatcctcta ccagctcgca ggcgtatctg taatggtttg
      361 gcagagggaa ctccccgtcc gccggaatat cgcccctaag tgccagaata ttctcaatgc
      421 cctgctcttt taactgcccg atcaccccgt gcacctcatc cttggtggac gatacgcagg
      481 taagatgggc caggcttgta acgccaaggt cgttcttgat ctgcgaggca atcctaaccg
      541 tatttctgct ggtgcctccg cccgctccat aagtcacgct tatgaaagag ggcctaagcg
      601 ccgcgatctt ctccgttgcc gctctcactc cttcatagcc ggcatccgtc ttaggcggaa
      661 atacctcgaa ggatacatgg ggagagttat ctttcagtat atctcttatc ttcatgtcaa
      721 tgctcctctt ttcgtatctt tctaatccca tacttcttaa atgccatcgt ataattcctc
      781 atattgcttt gcggaattct tccatgagaa atcctgattc atgccgcgtt ccacaatctt
      841 gttccagtca cgcttcttat catagtaaat gcgctccgca tagcggatcg ttgccagcat
      901 ctcatgggca ttatagttca tgaaactgaa tcctgtgccg gtcttttcat attcattgta
      961 tggctctacc gtatccttga gcccgccggt ctccctgacg atcggcacgg tgccgtaacg
     1021 aaggctcatc aattggctta agccgcaagg ctcgaacaga gacggcatca ggaatgcgtc
     1081 gcaggaagcg tatatcttat gggacaaagc ctctgaataa tagatattcg ccgatacctt
     1141 gcccggatat ttccatgcaa aatgccggaa catattttcg tacttttcat ctcctgttcc
     1201 aagcgccacg atctgaactg catcctggca aagttcatcc atcacatagg cgatcaggtc
     1261 aaaccccttc tgatccgtga gcctggacac gattccaagc attataatgt gatgatcctg
     1321 ctccaggttc aattcctttt gaagcgcgat cttattcttt atcttctccc tccggaaact
     1381 gtcacatgta tagtttttct cgatgtgggt atccgtggca gggtcgtaat cttcatagtc
     1441 aattccgttc acaatgccgg acaggcagtt cgagcgggca ttcataaggc cctccagttt
     1501 ctccccgtag aacggagtct ttatctcttc tgcataggag ttgctcaccg tggtgatccg
     1561 gtccgcatac acgatgccgc ccttcaggta attggcatcc ttgtacgctt ccagcttgtc
     1621 aggcgcaaaa taatactgcg gaagtcccgt aatatctctt accctcttgg tatcccatgt
     1681 cccctggaac ttcaggttat gtatggtcat gatcgtcttg atcccccggt aatactcatc
     1741 cccatagcgg aaattatcca gatataccgg tattagtcct gcctgccagt catggcagtg
     1801 aatgatgtcc ggccgaaagc cgattaccgg gagggcgctc aaaaccgctt ttgagaagaa
     1861 cgcgaacttc tcgatatccg cgtacatatc gccatatggc gcaaatccat taaaatagta
     1921 ttcattatct ataaaataga acgtaattcc atcgtactct aattccaaaa ttcctacgta
     1981 ttgttttctc caatttaaat ccatataaaa atgcgtatgg taactcagtt tttctttcca
     2041 ttcttccttc atgcacatgt acttaggcag cataacccgt acatcatatt tttctttgtc
     2101 gaaatatttt ggtaaagaac caacaacgtc ggcaagtcct cctgtcttta taaacggaac
     2161 cgcctccgaa gccgcaaaaa gtattttttt cattgctttt cctcccaacc cttcaatata
     2221 cacctattat agcgtatttt ttttaagaag aaaagtatta tctgttttta tattccaatc
     2281 tgatcgtatc tgcaatcaat gcgataaact ccgaattcgt cggctttcct ttgccattgc
     2341 tgaccgtgta gccaaacagg tcatccaggg tatccagctt cccacggctc caggccacct
     2401 caatggcatg cctgatggcc cgctctaccc tgcttgccgt agtctgatgc atctttgcca
     2461 ccgtaggata gagtaccttc gtgatcgcat tgagcacatc catgtcctcc actgccatga
     2521 taatggcatc ccttagatag tggtatccct taatgtgcgc cggaatgcca atctcgtgga
     2581 tcatatccgt cacccggttc tccagattca cctcgggcgc ttcttccatc ttaagcccct
     2641 gggcggattg cgtcttcatc tcatggcgta tcaggtgatt ggcgttctta atccggttca
     2701 agaccatctc gttgttgaat ggcttcatga tgtaatagct ggcgcctttc ctgaacgcat
     2761 cttctgtgat ccgctcctgc ccgactgccg tgacgacaat aaagtccggc tgtttcttca
     2821 agtctttatc acctcctacc atttccatca cgcttaatcc gtccatcttc ggcataatca
     2881 gatccagcag tacgacatcc ggctgctttt cttttatcag atggtacgca tcctctccat
     2941 tgttcgcctt tccgaccaga tttaattctt tatcgctgct gataatttcg ccaagcaaat
     3001 ctagaattct ctcattgtcg tcggctattg ctacgtttat ctctcccatt tttacgtatt
     3061 gcctcccttc cttacatgaa aaccgtcgat ttaaattata taatttgaca tattgcaaag
     3121 caagaaattg ctgtcgtaaa aacttgaccc gaatcgacaa atttatgaca aagtgacatt
     3181 tttcaacata ttttcaataa aaatgccata tcccttcgta gagtcctgga cgaaaacatg
     3241 cgtaaccgcg cccacgattt tcccattctg catgattggg cttccgctca tgccttgtac
     3301 gattccgcct gtaacttcaa ggagtttctt gtccgtgact tctatgacga gccctttgtt
     3361 gagctcatct gtatgcttgt cgacttttgt aatatgaatc tcataatcct tcacttctcc
     3421 ttcaacggcg caacgaattg tcgcaggccc ttcctcgatc tcgtctgtgg atgccgtctc
     3481 cataggcgtc tggtctgtaa acagtgcgtc aatgcggtcg atctttccga agatgccgca
     3541 gtccgtattc ttggttatgc ttccaagcac attataattg ttatagacta tgattccttc
     3601 catccctccc ggcgtgccgt ttacgccctt ctggatatct ttgatgctgg tctcgtacac
     3661 ggtgccgtcg ttaatctcca gcagcgtatt ggtatccaca tcatgaatcc catgtcccag
     3721 cgccccgaac tggctgtccg cattcaggaa tgtaatggtg ccaagtccct gggcattgtc
     3781 cctgacccat atgcccaact tgtaatcttt ggaactgcat ctgaccggct ttagcttgat
     3841 gtcgatcaga tcctctgagc ggcgcacctt gagtactact tcatctttgt caatcttctt
     3901 cattgcatcc actaattgcg acttgctgct gatttcttcc tcatccaggc ccacgatgta
     3961 atcccctgcc ttaaccaggt gggaggcagg ctcatactcc atgccgtcca tggctgtcac
     4021 cgcgtccgtg ccaagcacca tgacgccctg agtctccaaa tatatgccga tgggcatgcc
     4081 tcctgggatc accatatttc tggatgatgt cccggcgctt acttcctgtc gcagctggct
     4141 gtgcttggct tcaatcaggt agtagcctcc tcccactgca accgtaaatg taacgatcat
     4201 gatcaagatt ctccggtacc agtatttcct catgcttcaa aacctccaag aaaaagatag
     4261 atacccattc tcgggtatct atcttattat gtggcaattc tttataaatt actctggttt
     4321 attttgtctg tttcgcaagt tccttcatct ccacggcgct ttgtaccact gtatccgtaa
     4381 ttcttgcgcc gcccagtatc cttgccagtt cctcgatgga acgcttctca tccagcagtt
     4441 ctatgctggt ctttgtgtcg cctttcttcg tcgacttctc gatcatgtag tgatggtctg
     4501 ccatggcagc gatctgggca aggtgcgtaa tacagatgac ctgatgcttc gttccgataa
     4561 acgccatctt ttccgagact ttctgcgcgg tcctgccgct gatccctaca tcaatctcat
     4621 caaagatcag cgtctcgatt tcatcccgct ttgccatcac cgccttgatg gccagcatga
     4681 ttcgcgacag ttctcctccg cttgccacgc ctgccagcgg cttcaccggc tgacccggat
     4741 tcaaagagat catgaattcg atatcatcca tgccttcagc cgtatagtcc ttcgtggatt
     4801 caaactgtat ccggaacttc acattttcaa aattcaggtc tttcagcccc tcttcaatcg
     4861 cctgttccag tatcttggcc tgcttctttc gaatcttcgt aagcctggct gttgactgcc
     4921 ttagcgcctc ttcggccttg gcacattggt ctttcagccg caggatataa ttgtcgtaat
     4981 cttccagtat cccgatccgt tcttcctggc tggcacaata atccagtatt ttttccactg
     5041 tatctccata ttttgtctta agatggttga tttcattcag acggttttcc gtctcataga
     5101 attcttcatc ggaaaattcg caggtcttgc tgtaatccgc aagttcccgg ttgaagtcgt
     5161 tcaacaggct gtccacttcc accagctggt cataaagctg cgcggccctg tcatcatatt
     5221 cggatgcctc ggataacgcg cggatggcgc ggcttaaggc ctcgcttgca ttgccgcctc
     5281 cctcgctggt ataaagatac gcctcgttta cgctgtccgc gatcttcttg ctgttcgtca
     5341 tccggcgata cagggattcc agttcctcat cctccccggg aagcagatga gcttcctgaa
     5401 tctcggacac ctcaaacttt aagaaggata attccttggc ccgctgggat tcatccgcca
     5461 tggcctcttt cagttctttt tcgcaggctt tgtatgcttt gtaagcctgt gccgcctttt
     5521 tcttgtcttc tgccagatat tcccttgcaa atgcgtccac gatgccaaga tgattcttct
     5581 tgtacagcag agactgatgc tcatgctgcc catgaatatc aatcaaaata gatgacacct
     5641 ccttaagaag ccccatctgc accgtctctc cattgatcct gcttacgctt cttccggcca
     5701 tcagccgcct tgagagcgta accattcctt cttccggata gatatccatt tcttttaatt
     5761 tcttctgctg gctttcattt tccaccagaa atgtcagttc cacgaatcca tactccgcgc
     5821 cctggcgcag aatatccttg gtatagcgtc cgccaagggc aaggcttata gaacccagga
     5881 taatggactt acccgccccg gtctccccgg tcaggatgtt aagcccatcc ttgaattcca
     5941 cctcgatctc gtcgattaat gccagattct tcacatgtaa attctgtaac atactgcctc
     6001 ctacaagaca atcttgctaa tcttatccat tacctttacc gtatcgtcca cgcttcggat
     6061 ggcacacatg atcgtatcat cgcccgcgat gcttcccact acttcattcc actgcatggc
     6121 atcgatcgcc gcgcagactg ccattgccat tcccgctacc gtcttgatga ccagaatgtt
     6181 ctgtgccata tccatagaga catagccatc ccttaacacc cggatatact tctcgctcat
     6241 gccgttctct gcgctctgat gcaccgcata gcgctgcttc ccgttctcat aagggacttt
     6301 tgtaagcttt aagtcccgga tatccctgga cacggtggcc tgggttacct tgaacccttc
     6361 ctggttcagg tattcagcca gttcttcctg cgtctcgatg tggtgcttat tgatcagttc
     6421 aataatcttt gcgtgtctgt ttactttcat gatgttaatt tcctttcatc tttctacgta
     6481 gcgtttctaa aaagctgact ttgcttaact tcataatctt ggtggacgcc tcagatctgc
     6541 gcaccgttac tttatcgccc gtggtcagta ccaccgtatc cgcgccgtca aaggtggtga
     6601 atacttcctc cttagactca tggcgcccca tgccaatctc gatcccaatc tcatcatccg
     6661 aagacaggac gatgctgctt gtattcagcg catgggaaca gatgggggta atcacgatca
     6721 aggatgccgt aggctccacg atcggcccgc ctgccgacag attataagcc gtggatccgg
     6781 tgggcgtgga gatgataatg ccatctgcct cataggaatt gagcagttcc ccattcacat
     6841 acagctggaa atgaatgacc cgaagttctc ctttcctgga aatcacgata tcattcagag
     6901 acacgtcctt ggaaccgtcc tcaaagattc cttccagcat catccggtcc tcaaatgtat
     6961 agtcattgct tacgatctgg ccgatggctt cctcgatatt gccgacttcc acctctgtaa
     7021 gatagccaag ggttcccata ttgattccca gaataggcac atccctctcc cacaaaagcc
     7081 ttgccacttc gatcaggctt ccgtctccgc cgataacgat ggcgcattct atatcctccg
     7141 gtatggattc ttttatgata ttcttctttt catccttctg gcataagacg catttctttc
     7201 cttctgtctc cagaagcccc tttaccttcc tggtaatgat gtgatctaca tctttgccgt
     7261 cattggtaac gattaaaaac ctgtccatat tgtcctgcat tccttttaat tttttgccag
     7321 cgtgcaaaat gcctcttcca ccgtcttttc ttcttcgatt ccttctgcta tcctggcatc
     7381 ctccccgcat ttttccagat ggatcagata ttcgatattg ccttctggtc ctttgattgg
     7441 cgaaaactcc agattcagga tggaaaatcc tatggataag gcatattgaa ttaccataga
     7501 gatgacttcc atatgcgtgc gcttatcccg tactacgcct ttcttgccga ctttttccct
     7561 gcctgcctcg aactgcggct tgataagcgc cacgatctgt cccttatctt tcagataatt
     7621 atgaatcggc agcagcactt tcgtaagcga gataaaggag acgtcgatgg aagaaaaatc
     7681 taccggctct ccgatgtctt ccggcgtcac ataccggatg ttggtctttt ccatacagac
     7741 gacccgctca tcctgcctta atttccagtc cagctggcct cttcccacat caatggcata
     7801 gaccttcctg gccccattct ggagcatgca gtctgtaaat ccccctgtgg atgagccaac
     7861 gtcggtgcac acctttccat ccaccgtcac atcgaagttc cgaagcgcct tttccaattt
     7921 cagccctccg cggcttacat aaggaagcgt atgtcccctc acctcgattg cagccttctc
     7981 cggaaatgtg gccccggcct tgtcctctct ctgcccgtca acaaagacgc tgcccgacat
     8041 tatgattgcc ttggccttct cccgggaagc ggcaaggttt ctttttacca gtaatatatc
     8101 caaacgttct ttcatattaa ctcctataat ttgccataag cgtcctttat tcttcttata
     8161 atggattcca cgtcgattcc ggtctcctta cgcagcacgc cgatattccc atgctctaca
     8221 tagtcatccg gcaaagccag cgtcagtact ttcacgccca gatccttcct gcacgcatat
     8281 tccagcacat gctcgccgta tccgccggtc tgcacgtttt cttccaccgt cacgatcagc
     8341 cggtgattcc ggcacaagga cgcgattatc gcttcatcta taggctttac aaatctggca
     8401 ttgacgagag tgcagctgta tccgctctcc ttcaggcgct ctctcgcctg aagggcgctt
     8461 tcaaacatgt ggccaacgct caggatcgcg atatcctttt cttcatagag catctcgctt
     8521 ttgccgtata cgaccggcgc gcggaattgc ctgtacgcat cgaacgcgct ccctcttgga
     8581 tagcggatcg ccacaggccc atcataagac agggcaaagc gcagcatatc cgccaattcc
     8641 catttatgct tcggagtcat aacgaccata ttcggtatgc tgctcagata agacaggtca
     8701 aagattcctt gatgggtctc tccgtcgctt cctaccaggc ctgcccggtc tattgcaagc
     8761 acgaccggaa gattctgaag tgccacatca tggatcagct ggtcataggc cctctgaagg
     8821 aaggaagaat ataccgcaaa caccggcttc atccctcctg ccgaaaggcc tgccgcgaag
     8881 gtcaccccgt gctcttcggc gattcccacg tcaaaaaacc ggttcgggta catctgccgg
     8941 aatctggtaa gccccgtccc gtctgccatg gctgcggtaa tggctacaac atcaggattc
     9001 cttcccgcct catcgcacag gactttgccg aatacatccg tataagtatc cttgtctttt
     9061 ggcgtttcca gttcgcctgt ctccacctgg aacggaccta cgccgtggaa tttatccggc
     9121 ttaagttccg caggctcata gccttttccc ttttttgtca tcacatgcag cagcacagga
     9181 ccattgatct tcctggcttc tttaaatgcc ttgcaaagaa gcccgatatt atgccccggc
     9241 acaggtccca gataagtaat tcccatatcc tcaaagaaca ttcccggaac caccagctgc
     9301 ttgatgctgc ttttggtcct gcggatgtgc tcgatcaagg aatctcctac taagggaacc
     9361 ttctccagcg cattggtaac gccttttttc agtcctgtat atatgtccgc cgtgcgaagt
     9421 tctgccagat acttagacat gcctcctaca ttctctgaga tagacatatg gttatcgttc
     9481 aatacgataa taaaattcgt cttaagagaa gaagcattat taagggcttc ataggccatg
     9541 cctccggtta gagaaccgtc cccgattacg gaaacgacgc tgtagtcttc tcctttcaaa
     9601 tctctggcct gcacatatcc aagaccggcg gagatggaag tcgaactgtg gcctgtatca
     9661 aacgcatcac aggcactctc cttacgcttt ggaaatccac tcatcccgcc atatttgcga
     9721 agttcgtcaa agcctgcctt cctgccggtc agcagtttat gggtataagc ctgatgaccc
     9781 acgtcccaga tgatcttatc ttccggaaga tggaacatca gatgcatggc catggtaagt
     9841 tccaccacgc ccagattgga cgcaagatgc ccgccggtct tgctgatctt ctcgaccagg
     9901 aattcccgga tctccaaagc cagttcctcc agttcttcca ggttcagttc cttaatatca
     9961 ttttccttct gtatacgctc taacataatc agttaccccg ctatttctcc ctgtgaatca
    10021 actggagcag cagctgttcc aggaattcgt tttcttctga taactgatgc aggaggctta
    10081 ctgcctgatc tgatagttct tctaccattc tccctgcctc agcagtcccc atcaaggtga
    10141 catacgtagt cttctcgttc ttttcatcgc tgtgggtcgg cttgccaagc acctccttgg
    10201 tgctggtcac atccaggata tcatcctgga tctggaacgc gattcctaca tatcttgcaa
    10261 tcttttctat gatctttact tcctcctcgg aagcgcctcc aagaattgcc ccgaccatca
    10321 tggatgcctc gatcagcgcg gaagtcttta attcatagat cgtatccagt acttccttcg
    10381 gtatggaatg cccggtctct ttgacgtcaa tgacttgtcc cccaatcatt ccgtagatgc
    10441 cggccttttc ccccagcact cccaacgccc ttccgatgag aaggctctct tccggctcca
    10501 tgacaaacgc cttgaaagcc gtctcaaagg catagttaag cagcgcgtcg cctgccagga
    10561 ttcccatgtc ttccccatat acgatatggg tggtcttacg tccgcggcga tactcgtcat
    10621 tatccattgc cggcaggtca tcatggacca gggagtatgt atgaatcatc tcgatggctg
    10681 ccatgaatgg gcggatcagc gggctttccc cgccaaacag cctgtaagtc tcattcataa
    10741 gcatcggacg caggcgcttt cctccggcca gaaggctgta gttcatagcc tccatgatga
    10801 tgctctggaa tccttcttgc ctgggcaggt actccgtaag gattccttca atcttttcca
    10861 ccttatgctt catctgtgcc tgcatacaat acccattcgc gcatcctgta ttgccatcat
    10921 tcgataatgt atatttagaa ttcatgtgca tctccctctt catctaatac cagcattttc
    10981 ttctctacct tatctatctt ttcattgcac agcttcagca tatccattcc cttgtggtac
    11041 aggctgaaag aatcttccag ggagatgtct tccttctcca tcttgcggat cgcatcttcc
    11101 aactgtacaa acagttcttc cagggttgca ttctcctgaa tctttttgtc cttatccatg
    11161 ctgctcctcc ttcacatcct ccacagttgc ctgtaggatc ccatccgtca catatatgga
    11221 cagcctgtcc tgattccgga cctgcctgat actcttgatg gccttcttgt ctcttccttc
    11281 cacgtaagcg tatccgtggc tgagtttctg aagcggcgac agccccttca tcacttccac
    11341 gtataacgcc atcctatgcc tcgcatccct taccttcccc tccatcagca tcttcatcct
    11401 gtcttccatc tcagatagcc tctgctgctg ttcctgcagt ttgagccggg gatgaagata
    11461 tttcaggcgg gtgtggtatt cccgcagttt caggcgggct acctgtatct tctgattcag
    11521 cagccggttc atccgcaagc ggtactcctg catacccatc tgcacctgcc ggtaatcata
    11581 gacggccagt tccgcggctg ccgacggcgt aggcgcccga aggtcggctg cgtaatcggc
    11641 aatggtggta tccgtctcat gtcccaccgc tgagattacc ggaacgctgc attcgaaaat
    11701 cgcccgggcc acttcttctt cgttaaaggc ccacaggtct tcaatggaac cgcctccgcg
    11761 ccccacgatc atcacatcta ctccgtatgc ttccagcatc cggattccac gcacgatgct
    11821 ctccttcgcg ccttccccct gcacctgggc aggataaagg atcagctgga catagggatt
    11881 gcggcgtccg gcgatattca tgatgtccct caccgccgct ccggtgggcg cggtgacaac
    11941 gccgattctg cttgcaaagg atgggatcgg ctttttgtat tccggcgcaa acatccccat
    12001 ctcttccagt tcttttttca gcatctggaa tctctcatag agaagtccat ctccatccag
    12061 ccgtatctct ttggcgtaca gctggtagga gccgcttcgc tcatacacat ttacagagcc
    12121 caggaccacg atctgctggc cctcgctcat acgaaaagag agtccgcctc gctgcccggc
    12181 aaacataacg caggcaatcg ttccggactc atcttttaat gaaaaatata tatgtcccga
    12241 tgtgtgatac ttacaattag aaacctcgcc cttgacgtaa atgcggttca gcatgtagtc
    12301 ctgggtaaac atattcttaa tgtaggcatt cacctgttta accgtatata cattccgagt
    12361 cataacctac ctctgattaa tctacaagtt ttgcaagcac gccattgaca aatgagggac
    12421 cgtcctcgct gctgtacttc ttcgctagtt ccacagcctc gtcgatggcc acgcctgtag
    12481 gaacatcctc gtcccatctc atctcatata ctgccagcct caggatcgtc agatccacct
    12541 tgttcatccg gctcgtcttc cacctggtcg tatgctcgtt aatcagcgcg tcaatctctt
    12601 ctaccttcga cgcgatcttc tgtacctttt ccctgatata gtcaaggtcc ttttcacccg
    12661 caccctccag ctggccgaag tagagttcca gctgctccgg catatccccg ccagcgttga
    12721 attccactcc gaacagcatc ttgaagatgt gctctctttg ctctgtcctc ttcacttatg
    12781 cttcctccgg cacgtctact ccggcgattc ggatattcac atcggcaaca tcgaggcctg
    12841 tcatattctc gattgccgcc ttaaccttct cctgcacctt cgtagtaatc tctttgatac
    12901 tgtagccata cttcagattc agtgccaagg ataccgtcac gatcccatcc agcacatcaa
    12961 ctttgacgcc tttggacaaa gacttcatgc ccagtttgcc aatcagttcc cttgtcgcgt
    13021 ttcccgccat ggaagagacg ccgtccactt ccatagcagc aaggcctgca ataatcgcca
    13081 ctacttcgtc cgcaatcttc acctcgccga gattctcatc gccctttatt gtatacgtat
    13141 ttctttcttc tctactcatt acctgaacct cctgtctggt tttacacttc tagtaattat
    13201 atcaaattta cctacgtttg caaagtctta tctgccgaat tcggataact caagcccatc
    13261 gttgcgctct atggtcatgc ggatgctcca ttcattgatg aacagaagca gcggacggcc
    13321 cttcaagtct ttcaccttct tcatgtcgga tgtgcctgtc agtttatcca ggtcaatctc
    13381 cgtattctcg atccagcgga tatgctcgta tggaagagtg tccatgcgta tctccacatt
    13441 atactcgttt tccagcctgt atttgagcac gtcaaactgc aggacgccca cgacgcccac
    13501 gatgatctct tccattccag tgttgtattc ctggaagatc tggatcgcgc cttcctgggc
    13561 aatctggttg attcctttaa tgaactgctt ccgcttcatc gtgtctacct ggcgcactct
    13621 tgcaaaatgc tccggcgcga atgtagggat gccttcgtag acgaatttat caccggcatt
    13681 ggtaagggta tctccgatcg agaagatacc cggatcaaag actccgataa tgtctccccc
    13741 ataggctttc tctatcatct tcctctcgct tgccatcatc tgctggggct gcgacaggcg
    13801 caccttcttg ccgccctgta tatggaagac atccatgcct gcctcgaatt cgccggaaca
    13861 gatgcgcatg aaggcgatcc ggtcccggtg agccttattc atgttggcct gaatcttgaa
    13921 cacgaaggca gaaaagtcac cctcttccat gggatcgatc aggcccctgt cagattttct
    13981 tggaagcggg gacgaggtca tcttaaggaa atgttttaga aacgtttcca caccgaagtt
    14041 cgtaagggct gagccaaaga ataccggcga gagttcgccc ttgctcacca gttcctggtc
    14101 aaactgagcc ccggctccat cctgaagttc gatttcctct tccagctgca ctctctggga
    14161 gtctctgata agccatgcga tctccggatc ggcgatatct accttcttca cctctccctg
    14221 ggtagtgccc ttgcgggtgt cagaaaacag ttctaccttc ttcgtctccc tgtcatagac
    14281 ccctttgaat tccttgcctg agccgatcgg ccagtttatc gggcaggtgg cgattcccag
    14341 ttcattctcg atatcatcca gaagttcaaa ggtatccatt gcctccctgt ccatcttatt
    14401 gataaaggta aagatcggga tgtggcgcat ggtacatacc ttgaaaagtt tcctggtctg
    14461 cgcctccacg cccttggacg catcgattac catcaccgcg gagtccgccg ccatcagcgt
    14521 acggtacgta tcctccgaga aatcctgatg gcccggcgta tccaggatgt tgatgcagta
    14581 gccgtcaaaa ttaaactgaa ggactgagga ggtgaccgag atacctcttt ccttctcgat
    14641 ctccatccag tcggacaccg catgcttagc cgtggccttt cccttgacgc ttcccgcctg
    14701 gttgatggct cccccgtaca ggaggaactt ctccgtaagc gtagtcttgc cggcatccgg
    14761 gtgggagatg atggcaaagg tccttctctt ttttatctgc tcttttactt gattatttat
    14821 ctgtgacata gattcaaaca ctcctacaaa tagtatatcc gcatatagac gctattagac
    14881 agtataacac acctggaatc aatcctcaat tgggaatttt gtttattagg ggacaggtga
    14941 ttggcgtgta acgcgcggcg gacggatggg agcgggcttt aggatacgcc gttcgccgga
    15001 acagataaaa gccagcctat ataagaagca taattgcctc ctattagact ggcctgcaaa
    15061 ctggtttatg tagttttatg tatagtctgc gggtgataag ccgctatcgg cgactctttc
    15121 gcgggcttac agatcagtgc aagagatgca ggcgccaaag cgtcgcagga atcaccgccc
    15181 cagcctcgcg ggcgggtcgc caatcccccc tactttcctt cggaatacac cggcgtaatc
    15241 acgatgtttt gtgccgccac gccagtctta cgggtaatga tgtcttcgat ctgcgcccgg
    15301 ttggcgtcgc ttaattctgc cgcattcacg actacgtctg ccgcatcctg ggtcaggctt
    15361 actacggcct cgctgaagcc tttggatgcc agaagcgtct cggctgcagc ttctttttcc
    15421 gcaatatccg tcattgccac catctggttc accgcgtcct gtttctgctc atcgcttaag
    15481 ttctcgttgt cgatgatttc catcagggac tctttgttct tggctcttac ttgttccctg
    15541 gtcacctttg cttctgcaac cacggcgctt gcctcgccgc ttgttagtac agcctctccc
    15601 ggcgtcccgt ccacgcttcc gtcgctgtcg gtgccgtcct ggctcttgat atcatcggac
    15661 gcgcttgtcg tcacatcctc ctcagatatg tccagaagtt ccttatttgc aagttctgca
    15721 ttcgtctttt ctgccgtatc cttatccccg aataattttc cggagtaatt cagatatcct
    15781 gccgccgcaa tcattacggc caatgctgca ataataatct ggttcttttt aaagattcgt
    15841 ttcactgttc atcctcctac cttgccacat cgtttatgaa ttcttcttca ttatcctaat
    15901 cttatgcgtg tctatcccaa ataatgcttg aactgcttca gtaatattct gttttaccac
    15961 tgcattatct cctccggagg ctatgactac cactccttct acctgagggc tcagttcctt
    16021 gctgatataa ggcgcctgcc cctgggatcc atctccgtca tatacggtgg actctccatg
    16081 gctgctgttc tgggtcgtgc gcgtccctcc ctggctgtct gactccgtaa ccgtctcgct
    16141 ttgtgcctcc acatccttct ccaccacttt ctcggctgag gattttaaag ttatcatgac
    16201 ggtcacatcc ccgaccccgg ccatctgtga cagcacgccc tcaaggtgcc cttccatata
    16261 agaagcgtaa ttgccatacg ccgcctctcc tcctccctct gccgccgtgc tgctccctgc
    16321 atctttggaa gcagcatcct tccccttccc tgtgggaatg gcgattacga ccagcaatat
    16381 tcccaccaga agcagaatca gcagctggtc cttttttaac tttttaatcg aaaaattctt
    16441 cggaatttca aatcgtttct ttttcttaac gtccaatctc tatctcctcc acctctatcc
    16501 cggtttcctc atcttccggt tcctgcccgg catcgtccgg atagccttct ggcagcgtct
    16561 cgccaagata cttggattct tcctctatct ttttcatctg ctcctgatac tctttgctgt
    16621 catacagact ccccagcgga tgctccatgc cgaatatctt aagtaaaggc gtggcaagca
    16681 tgacgaccag caccattccg gtaaagaacc gaatatactt tttataatcc gaattcggaa
    16741 ggatatggat gaccgccgta ataagcacca tataaaacgc aatattcttc atccattcat
    16801 ataaatattc aaacatagcc acacctcaga cattactggt tactgcagat acaatggcaa
    16861 tggtcagaag gaacagaagg cccgtagtaa ataccacccg cataagaagc tggcatccgt
    16921 ctcccactgt ctcaacacag cctacgatac gcttgtcgga taccggctgt atgattgccg
    16981 ccgccagctt atataaaaag gcgatgcagg caatctgagc cagcggcacc acgcacaggg
    17041 cgatgcagat gagagcccct gtcatcccga ttccattctt caccagcacc gccgtgccaa
    17101 gagccacctc cgccacgccg cctatggcat ccccgatgcc agggatagct tccgcgcctc
    17161 tggcgatggc gcttcttttc acagaatcaa tggccgggct tatcattccc tggatcacgt
    17221 tcagcccgat gatgcaggcc agcagcgtct ttaatatcca cgacactgaa acctgtatca
    17281 gttccgcaaa cttgcttaga tattcctcag aggaaaggta attcagcacc cgtaccatca
    17341 tatagatatg gatcacgggc agaaggaagc tggtgatcag aagttctaca agaaagatta
    17401 aaaacagcac cagattataa aacgcaatgg aagtaacgct gccttttgca attgccactg
    17461 ccaggaaata taaggggcag aatacgccca tgaatgaggt caggctgtct atcccctggc
    17521 ctacccactc caccaccacc tggaatgaac ttaatgccaa tgcaatcaga agcagataca
    17581 gggcgtaaaa actgatttcc gatatctggc ggctctggaa tacgtttgaa aaattgctga
    17641 atacggccgc aatgaccgcg atcagaagga tatgtaccag attgtccttg cagcttctaa
    17701 acgcatatcc cagctgatcc gataccagcc ggttcagcag ctgggcggaa aatgtcagat
    17761 ccccggaaat gactcccata agcgtttcct taaagtccag cttctcttcc ggaaagagtt
    17821 cctttaagga atcgtcaatc tccccaaaat cgaactcccc gatcaaatcc tcctgcatcc
    17881 cggaactctc tgccttatcc tcattagttc ccgactgcct ggcctctttg gcctgtgccg
    17941 gcagcgggga aaatattagg agcaggataa cccacaggat ggctgcctgt accatttttc
    18001 gccgcctcat gacagaaagt cctttatggt atttaaaagc gccatcagaa ccggcatgct
    18061 caataccaga accgccagct tgccgaatat ctctatctgc agcgcgatgg tctgatagcc
    18121 cgcgtccttg cagatgcccg cggaaaattc ggccacatag gtaatcccca gcatctttat
    18181 cagcgtcccg atataggcgg tatccatatt gatataattg gcgatggttc tcaaggcatc
    18241 gatgatcact tccagccggc cgataatggc aaagaagatg accaggctga gtgccacgct
    18301 gatatagatg ccatactcag actttccgct tttaaactgt acggccagca gggtgccggc
    18361 gaccccgatg atcccgatct gtatcatatt catgggcatt ccttctttct acagcgaaaa
    18421 taaatgctgg atggattcaa acaggtcata gatgtatggc acgatccaga acagcaccag
    18481 cagaagcccc gcaaggcttg taaggaacgc ctgctcttcc cttccgctgt gctttaagac
    18541 ctggcttaag acggagacca ggattcccac cgcagctatt ttaaatatta gatttacact
    18601 catgcacgcc tcctctatat taacaggacg gtaataaata tcccgctcat cacacccagg
    18661 cagtggcata atctcacctt tgccttcatc ccgccccgca tctcttccat ggaaaggctc
    18721 atttcctcca ggtagaggtc gagagtcttt acctgcatct caatatccgc gacccccagc
    18781 tggcctccaa gatttatcag tttgtccagt tcctcatccg gaaggcctga tgcccccaga
    18841 tattctctta ccgtatcttc ccatatatcc gccagcgttc ccctgttctt atgctccagc
    18901 ctgtcgtata tttccagaat ccatccttta tacggctccc tggaagatgt cccaatgtga
    18961 cgaaacgctt cccccagata agacctggca taccgtatct cgcttcttaa ctggtagatc
    19021 agcttcttga gatactgcat ctggacatac tggtcgttga tacggtctgc cgcccggatg
    19081 ccccataaag aggtggctcc tatgatcagg acagccccga aggtctttac cattgccgtc
    19141 atctgacatc ttccctgtac agaaggctgc cccggtgatc gaagatgcca tcgatctgcc
    19201 ccacgtgcgc gcggtttccc aaaagaatgt accgttcaaa gcgtccctgg tcgatcatcc
    19261 ggtcaaggag aggcttcttt cttaattctt ccatggaacc tgcatggaca gtggccagca
    19321 tcttgcagcc gcagtgcatt gcgtattcga tggcatgtac atcttctgcc gatccaatct
    19381 catctacggc aatgacttcc ggtcccatgg agcgtatcag catgatcatg ccttctgcct
    19441 tggggcaccc atccagcacg tccgtgcgga ttccgagatg gttctgggcg acccccatat
    19501 agcagcctcc aatctccgac ctttcgtcca ccacccccac agccatgccc ctcacccagt
    19561 catttccatc ggagatctga cggatcatat cccgaagaag cgttgtcttg ccgcatcttg
    19621 gcggcgatat gaccagcgta tggtataggc ttctgttata ggtaatatgg ggaaatactt
    19681 tatctgcaca accaagtact tcatgggaca tccgcacatt gacggatgag atatgcttca
    19741 ggttctttac tttgccgttc tctataattg cctgtcctgt cattcctact ctgtgtcctc
    19801 cttcaatcgt gataaatccc tgcttcattt cctgttcgta tgcatataag gaataattgc
    19861 tgatatattc cagcatctct cttacatctt cttttgtaac catataaggc ttgccgcgct
    19921 gccctcccaa gatcagttct tctcctctgt agatcagaag cagcggcttt tccacccgca
    19981 gcttgatctc ctgcaggtgc tcgtactgca gctgctcctt atggatcaga atgcgtacgc
    20041 tgcgcggcaa gacatttaag attctgttct cctgcatatt tgtccacctc tttacaccaa
    20101 tatatgagac gacttttaat ttattcccaa atatgttaca atccgtatat tcaagtatct
    20161 gatttctacg gaaaggatga atttgctatg atcgctgtat ttcttgcgcc tgtctaccta
    20221 atattaaatg cttatatctt ccgctggctg atccgcttta tgggagcctg cacgcatcat
    20281 ttccaaaaga cttgggtcag gctgatcgtt ctggccttct acggcttttt ggccttatcc
    20341 atcctgctgg ccttcttctg gcctgccaga tggctgatct acatttcaaa tatctggttt
    20401 ggcaccctct gctatatcct gcttaccatc ctggttgcag atggcatacg cctgatcgca
    20461 aaactgatcg tcaagcgcat gaagaagcgg gaatggaagg aatcccggag gctcttcgtc
    20521 gccagcggca ccctctgcat ttccttgatc ctctcccttt ccgtctatgg atatctaaat
    20581 gcccgccaaa tacataccac agattattcc gtaaccatta agaaatcttg caaagatctg
    20641 gattccatga aagtcgtcct ggtagcggat ctccacctgg gctacagcgt gggaaatgcg
    20701 cagatgtccc agatggtcag gaagatcaat gcccaggatc cggatctggt ggtaatcgcg
    20761 ggggacatct tcgacaataa ttacgatgct ttgaaaaatc cagataagat cgcccgcacg
    20821 ctgcgtggta ttaaaagcaa ctacggcgta tatgcctgct acggcaatca cgatatccag
    20881 gaaaa
//
