LOCUS       NZ_CP036170            42229 bp    DNA     circular CON 15-DEC-2024
DEFINITION  [Clostridium] scindens ATCC 35704 chromosome, complete genome.
ACCESSION   NZ_CP036170
VERSION     NZ_CP036170.1
KEYWORDS    RefSeq.
SOURCE      [Clostridium] scindens ATCC 35704
  ORGANISM  [Clostridium] scindens ATCC 35704
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Lachnospiraceae.
REFERENCE   1  (bases 1 to 3658040)
  AUTHORS   Devendran,S., Shrestha,R., Alves,J.M.P., Wolf,P.G., Ly,L.,
            Hernandez,A.G., Mendez-Garcia,C., Inboden,A., Wiley,J., Paul,O.,
            Allen,A., Springer,E., Wright,C.L., Fields,C.J., Daniel,S.L. and
            Ridlon,J.M.
  TITLE     Clostridium scindens ATCC 35704: Integration of Nutritional
            Requirements, the Complete Genome Sequence, and Global
            Transcriptional Responses to Bile Acids
  JOURNAL   Appl Environ Microbiol 85 (7), e00052-19 (2019)
   PUBMED   30737348
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3658040)
  AUTHORS   Devendran,S. and Ridlon,J.M.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-FEB-2019) Dept. of Parasitology, University of Sao
            Paulo, Av. Prof. Lineu Prestes, 1374, Sao Paulo, SP 05508000, Brazil
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu v. 1.5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 300x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004295125.1-RS_2024_12_13
            Annotation Date                   :: 12/13/2024 14:32:22
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,771
            CDSs (total)                      :: 3,697
            Genes (coding)                    :: 3,591
            CDSs (with protein)               :: 3,591
            Genes (RNA)                       :: 74
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 30 of 106
            Pseudo Genes (incomplete)         :: 86 of 106
            Pseudo Genes (internal stop)      :: 13 of 106
            Pseudo Genes (multiple problems)  :: 19 of 106
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:01:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1735043
            Orig. end                         :: 1777272
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP036170.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..42229
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /candidate_cluster_numbers="4"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /product="lanthipeptide-class-ii"
                     /product="sactipeptide"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /rules="cds(LANC_like and DUF4135)"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     cand_cluster    1..42229
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="neighbouring"
                     /product="RRE-containing"
                     /product="lanthipeptide-class-ii"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /protoclusters="2"
                     /protoclusters="3"
                     /tool="antismash"
     cand_cluster    1..20366
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20366
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10366](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10366
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     gene            1333..2124
                     /db_xref="GeneID:62695985"
                     /locus_tag="HDCHBGLK_RS08915"
                     /old_locus_tag="HDCHBGLK_01776"
     CDS             1333..2124
                     /codon_start=1
                     /db_xref="GeneID:62695985"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009249439.1"
                     /locus_tag="HDCHBGLK_RS08915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_01776"
                     /product="nitroreductase family protein"
                     /protein_id="WP_004608375.1"
                     /sec_met_domain="PF00881 (E-value: 7.2e-23, bitscore: 79.3,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRIEKERCIGCGACIKDCPASAIRMTEEKAEAYKDCLLCGHCVA
                     ICPSEAVSIPEYDMEDVEAYDKDTFTLKAEHYLHAVKFRRSIRNFKPEKIEREKAERIL
                     KAGRYTATAKNRQACTYVFIQEQLDEFKELVWKEMPSILEELKQNAPDYARAFELFYLK
                     WKRNPKDDTFFFNTPAFLVIASNNPLDGGLAAANIENMAVAEGLGALYSGYMMRVIGLS
                     QTLREWLGIGEKRVSCCMLLGYPAVSYRRTAPRKYADILWK"
     gene            complement(2153..3280)
                     /db_xref="GeneID:62695986"
                     /locus_tag="HDCHBGLK_RS08920"
                     /old_locus_tag="HDCHBGLK_01777"
     CDS             complement(2153..3280)
                     /EC_number="2.7.1.31"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:62695986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015520229.1"
                     /locus_tag="HDCHBGLK_RS08920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_01777"
                     /product="glycerate kinase"
                     /protein_id="WP_039910047.1"
                     /transl_table=11
                     /translation="MKVVVAMDSLKGSLTSMEAGIAVEEGILAAKPDAKVIVKPLADGG
                     EGTTDALIEGMKGERVDLTITGPMGTKVHAYYGYLEETKTAIIEMASAAGITLVPTDRQ
                     DPLSATTYGVGEMINDAITKGCRNFIIGIGGSATNDGGIGMLKALGFVFLDSQGNDVGE
                     GAQALSKVAAINSAKKNPRLAECTFQVACDVTNPLCGKSGATYIYGSQKGVTEEQKDAL
                     DQAMTHYAQITADTFGCSYAETEGAGAAGGLGFAFLSFLNARLTPGIDLILDAVGLEEE
                     LRDADVAVTGEGRLDHQTAMGKAPVGVARLAKKYNVKVLAFAGSVTKDAASCNQAGIDA
                     FFPIVRGVTTLEEAMKPERARENMRASVEQAFRLL"
     gene            3752..4954
                     /db_xref="GeneID:62695987"
                     /locus_tag="HDCHBGLK_RS08925"
                     /old_locus_tag="HDCHBGLK_01778"
     CDS             3752..4954
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:62695987"
                     /gene_functions="other (smcogs) SMCOG1237: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009249946.1"
                     /locus_tag="HDCHBGLK_RS08925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_01778"
                     /product="IS110 family transposase"
                     /protein_id="WP_009249946.1"
                     /transl_table=11
                     /translation="MISVGIDVSKGKSTVCILKPYGEIMCSPFEMLHGEKELNALDDLL
                     NKLDGEIRIVMEATGIYHLPILTFFHEKGYFVSVINPFAMKKYAKDNSIRGAKTDKLDS
                     IMIANYGIEKWFKLQRYKGDEEIYAELKLLGRRYRHYMELHVKALQELTHILDYVMPGI
                     KKMFNSWNEANGKDKLSDFVEQFWHFDLITAMSLEKFTEEYLDWAKEKKYHRSRSKAEA
                     VYELASNGISTLSSGTPSTKMLVQEAISVLRTVDSSLFLILTRMQELAKTLPEYSTVRE
                     MGGVGDVLAVKLIAEIGDIRRLHSAKALIAWAGIDPPPYESGQFIGSKRKITKRGSSTL
                     RKVGYEVMRVLKSHPAPKDDAVYNYILKKESEGKSKKHAKIAGLNKFLRIYYARVMAVY
                     Q"
     gene            5172..5411
                     /db_xref="GeneID:62695988"
                     /locus_tag="HDCHBGLK_RS08930"
     CDS             5172..5411
                     /codon_start=1
                     /db_xref="GeneID:62695988"
                     /inference="COORDINATES: protein motif:HMM:NF013828.5"
                     /locus_tag="HDCHBGLK_RS08930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /protein_id="WP_004608370.1"
                     /transl_table=11
                     /translation="MGVYGVTAAGKSYFLPACCVEACRLNYRCKFVDYCDLLDELIVLN
                     RLEDLSRYRKRIRYYARIQLLFIYDFAISRYSEE"
     gene            5636..5923
                     /db_xref="GeneID:62695989"
                     /locus_tag="HDCHBGLK_RS08935"
                     /old_locus_tag="HDCHBGLK_01779"
     CDS             5636..5923
                     /GO_component="GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:62695989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004608369.1"
                     /locus_tag="HDCHBGLK_RS08935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_01779"
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="WP_039910045.1"
                     /transl_table=11
                     /translation="MNIRPSAAIRQNYNEIADMCRKTAEPIFLTKNGEGDLVVMDIETY
                     NRREKMLKLREELLAVEEDRMHGSTGYSVGEVAAMMRSAIKEAAGHGKTE"
     gene            5907..6224
                     /db_xref="GeneID:62695990"
                     /locus_tag="HDCHBGLK_RS08940"
                     /old_locus_tag="HDCHBGLK_01780"
     CDS             5907..6224
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]"
                     /GO_function="GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]"
                     /GO_process="GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:62695990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004608368.1"
                     /locus_tag="HDCHBGLK_RS08940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_01780"
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_004608368.1"
                     /transl_table=11
                     /translation="MEKQNRYRVIVSERATQMLVSHAAFLAQVSPEEAERLTAEFEKTA
                     NSLETMPQRCPWLTGEYIPRNAYRFILFEKRYMIIFQIVDDIVYADYVVDCRQDYSWLI
                     R"
     gene            6761..9304
                     /db_xref="GeneID:62695991"
                     /locus_tag="HDCHBGLK_RS08945"
                     /old_locus_tag="HDCHBGLK_01781"
     CDS             6761..9304
                     /codon_start=1
                     /db_xref="GeneID:62695991"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HDCHBGLK_RS08945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HDCHBGLK_01781"
                     /product="FtsX-like permease family protein"
                     /protein_id="WP_004608366.1"
                     /transl_table=11
                     /translation="MRKKVFRILCIIFSAGVFMSVFYPWTVLNGESYTIIEFYKQAVFD
                     KQLYTMADMGGSVYLLLIFLIFPMVVGILSGVKAVLLVFRKNYYLLGEIINISELISVA
                     AFFAFQGYELLTAPFFQAIFVFLEFMMECYLSDVDRFTNEWEIHKIKNRTEKEERKQRL
                     AFPGNYDRRLRKIIRKDALHPSKAVVLVCIGNGILLGSAFALFAVKEQFQKNYSAKAVL
                     PTEGLNGILTNGLLVITIFYIFFAIAAFFNYVHNHQERRNLFWTLGSRERLNSIAWKME
                     YEFMIVLSMIPGYIIGVGIYNLLRVMLKKELGVLIDGRTQLQLYFLSGLLYLCLSGVII
                     WLSSILLRKELRGEKRNIRKLSTPTKGVAVITVMLSLGYLVFSIGRYMQRRNGESLNIF
                     VYGIILGGICVLCSIRLLESLNRRGKAQNFQVLLDKIPMQSGFFKEAGLQSVVFAFHFI
                     FLGFLSVTMAGKLSAPSPDTLFPHEYVCMAYPEDEELFTELRDKNLADVKSYPMIRVTS
                     VQGNPTDWIDIANNYYRKIIWPQGQHIGISRSTYESLCTDEKKNISNFTLSEDEIYVVY
                     QEDCSVKAHPLEWYMNRRTPFIKEGQPLRWYNPFARENYYPPRKVIGQERKVLTGVFER
                     GIQEHIVVFSDDYFNQLHDVDGPSVLYFVDCLEKNKKEVEKVLSVFASRHMEDSSWDRL
                     IQPYYSKTEKITDMEAERKLEQISTSIEMLLSVFCVFIFCFIKIEFEQEEKQKRFQTLF
                     CLGMHKKQVKHSLWREICRFISLPLIFAYTLATVVVTFIWKMRFVTGAESRKLWMTLII
                     IWTIYLLLQMLLTFVLYRYQLNNLNLKNGVRGRRR"
     gene            9301..9978
                     /db_xref="GeneID:62695992"
                     /locus_tag="HDCHBGLK_RS08950"
                     /old_locus_tag="HDCHBGLK_01782"
     CDS             9301..9978
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:62695992"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004608365.1"
                     /locus_tag="HDCHBGLK_RS08950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_01782"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_004608365.1"
                     /transl_table=11
                     /translation="MKIELKDIKKSYQIPGQDEFKVLKGINFLISQGEYISIIGRSGCG
                     KTTLLKIVGLLDIPTEGDVIIDGVKEKELWNDELADLRRRKLGFIFQDYFLLEHLTVLD
                     NMILPALLDKAEEKKSLERAEELANYLQIDNRLLLKYPKELSGGEKQRVAIARALFNDP
                     DILLADEPSGNLDEQSKKNVEKIFKDLHENINKSILLVTHDLEFAKWSEKCYQLQNGVL
                     VKG"
     gene            10001..10366
                     /db_xref="GeneID:62695993"
                     /locus_tag="HDCHBGLK_RS08955"
                     /old_locus_tag="HDCHBGLK_01783"
     CDS             10001..10366
                     /codon_start=1
                     /db_xref="GeneID:62695993"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Other_Sactipeptide_rSAM_RRE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HDCHBGLK_RS08955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HDCHBGLK_01783"
                     /product="hypothetical protein"
                     /protein_id="WP_050755157.1"
                     /sec_met_domain="Other_Sactipeptide_rSAM_RRE (E-value:
                     4.7e-18, bitscore: 63.3, seeds: 13, tool:
                     rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEKPFIHLFKTTKGQYCYDVNKDEIIQLPDDVYMYLAGKGEKTD
                     YVKTYIEQLYERGYLKSKRVITTKHPATDYLSYYYDTKLNFLILQVTQNCNLRCEYCVY
                     SGNYRTRSHNNKRMSLI"
     aSDomain        10007..10354
                     /aSDomain="Other_Sactipeptide_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a sactipeptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_HDCHBGLK_RS08955_Other_Sactipeptide_r
                     SAM_RRE.1"
                     /evalue="3.60E-20"
                     /identifier="RREFam021.1"
                     /label="HDCHBGLK_RS08955"
                     /locus_tag="HDCHBGLK_RS08955"
                     /protein_end="118"
                     /protein_start="2"
                     /score="63.3"
                     /tool="antismash"
                     /translation="EKPFIHLFKTTKGQYCYDVNKDEIIQLPDDVYMYLAGKGEKTDYV
                     KTYIEQLYERGYLKSKRVITTKHPATDYLSYYYDTKLNFLILQVTQNCNLRCEYCVYSG
                     NYRTRSHNNKRM"
     misc_feature    complement(10725..10738)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.7"
                     /tool="antismash"
     gene            10898..11161
                     /db_xref="GeneID:62695994"
                     /locus_tag="HDCHBGLK_RS08960"
                     /old_locus_tag="HDCHBGLK_01784"
     CDS             10898..11161
                     /codon_start=1
                     /db_xref="GeneID:62695994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002586246.1"
                     /locus_tag="HDCHBGLK_RS08960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_01784"
                     /product="CD3324 family protein"
                     /protein_id="WP_004608363.1"
                     /transl_table=11
                     /translation="MKYFNAKLILPDALVKELQNYVQGGYIYVPIEQEQQKRWGEVSGY
                     RQELEQRNEQIKREYQNGISMECLSEKYGLSFYAVRKIIYQK"
     misc_feature    complement(11214..11232)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 24.86"
                     /tool="antismash"
     gene            11294..12049
                     /db_xref="GeneID:62695995"
                     /locus_tag="HDCHBGLK_RS08965"
                     /old_locus_tag="HDCHBGLK_01785"
     CDS             11294..12049
                     /codon_start=1
                     /db_xref="GeneID:62695995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004608362.1"
                     /locus_tag="HDCHBGLK_RS08965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_01785"
                     /product="conjugal transfer protein"
                     /protein_id="WP_050755156.1"
                     /transl_table=11
                     /translation="MCTRFVYRGDDMITGFNLDIDLSVWKHKVIEEKERFYIGILRPDG
                     TYHSYHGVNKNGNVGTLLYVHGNPAGAYQDCPNCMTIADLTEQFIKAQISFDEVLQILK
                     SKRITYAPDATMQAMLSDVYGRVLIIEPGIGYWEEHKRYSLITNYSLMNPESTKNFIVQ
                     GDNRYERALQLLDSYKNDFSISDAFALLHTVRQEGEWATRVSFVYSVKEQAVWYAENNH
                     FEHITKFVFPSEQQERSSHAAENLSSFKG"
     gene            12015..12635
                     /db_xref="GeneID:62695996"
                     /locus_tag="HDCHBGLK_RS08970"
                     /old_locus_tag="HDCHBGLK_01786"
     CDS             12015..12635
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:62695996"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1156: Chloramphenicol acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004608361.1"
                     /locus_tag="HDCHBGLK_RS08970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_01786"
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="WP_004608361.1"
                     /transl_table=11
                     /translation="MQQKIYPRSKDKETVYLQNVITNPNIIVGDYTIYNDFVREPRDFE
                     KNNVLYQYPVNKDKLIIGKFCSIACGAKFIFNSANHTLSSLSTYPFPIFFEEWGLDVRN
                     ITKAWDNKGNIVIGNDVWIGYEAVILSGVTIGDGAIIGTRAVVTKDVPPYTIVGGVPAQ
                     TIRKRFSQDTIDTLLKIKWWDWSKERITQHISEIQSGNIEHLI"
     gene            12974..13426
                     /db_xref="GeneID:62695997"
                     /locus_tag="HDCHBGLK_RS08975"
                     /old_locus_tag="HDCHBGLK_01787"
     CDS             12974..13426
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:62695997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004608360.1"
                     /locus_tag="HDCHBGLK_RS08975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_01787"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_004608360.1"
                     /transl_table=11
                     /translation="MNDSEQYKEHIEYTFAAFCKVVLRNASLSAYRDIARRQKREISLD
                     YLMEGRYYNPSTTDSYFAKQTSSMELIVCGERIVIENERLAKVFSGLPKLRQEVLVLYF
                     FFGYTDKKIGEMYGKSRTTVNYWKIAALKYLRKEMECKLRLNGDVG"
     gene            complement(13584..15149)
                     /db_xref="GeneID:62695998"
                     /locus_tag="HDCHBGLK_RS08980"
                     /old_locus_tag="HDCHBGLK_01788"
     CDS             complement(13584..15149)
                     /codon_start=1
                     /db_xref="GeneID:62695998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009662223.1"
                     /locus_tag="HDCHBGLK_RS08980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_01788"
                     /product="transposase"
                     /protein_id="WP_233440750.1"
                     /transl_table=11
                     /translation="MMYAVVTYANMRGIRAVDRIVELCERDLAFIWLTKGQKPKRDAFY
                     EFKNKRLTADVLDELNYQFLRRLQKEGLITLKSLFIDGTKIEANANRYTFVWRGTINYH
                     LAGLLDMIDSLYQKYNAWIDENEYGIKYDIPHAHMFVIEGMDKVRDVIEKNRKRKLTKH
                     KKLSNNTIIEIDNCSPLEILKLQKNLTQIAEKEQIAFVYGKGKRKSELQQLYEELETCG
                     ERLMGYKECFEIMGKDRNSYSKTDLEATFMRMKEDHMLNGQLKAAYNVQIAVENYFIVH
                     AYVSNDRTDYNTLIPVLEKHKNAFGEILEEVTADSGYCSEKNLLYLKKNKISSYIKLQD
                     HEKRKTRAYREDIGKYYNMKTQIFEDERYYVCHDGRELHHIRTETKKQPGYTQTFEVYG
                     CADCSGCEHKAKCLYKYNAEKDAEKNKVMKINEQGETLKEESHANIQSEKGILNRQIRS
                     IQTEGHFGDIKGNDSFRRFNYRTSEKVYKEFMLYAIGRNMNKYHRFLHDEIKKFEGKTE
                     EKTA"
     gene            15342..16913
                     /db_xref="GeneID:62695999"
                     /locus_tag="HDCHBGLK_RS08985"
                     /old_locus_tag="HDCHBGLK_01789"
     CDS             15342..16913
                     /codon_start=1
                     /db_xref="GeneID:62695999"
                     /gene_functions="other (smcogs) SMCOG1213: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004605805.1"
                     /locus_tag="HDCHBGLK_RS08985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_01789"
                     /product="Mu transposase domain-containing protein"
                     /protein_id="WP_004605805.1"
                     /transl_table=11
                     /translation="MHDYTTIIGVIELRLNKISYDNVQKRYRIGRSGISLIMERYRDSG
                     LSLDDLKQMPAEKVVNLIYPKDNLRHKNIPLPDFHQIHENMIQMGKNADLGFLWIEYKK
                     KNPNGYQLSQFYKLYRDFLVNTYGSTKVSMPVERIPGEKMYIDWVGDQPELLLDPSTGE
                     LKKVHIFATTLGFSSLVYAEAFPDEKLPHFITGTVHALSFYGAVPRYLVPDNLKTAVTR
                     HNKDELVLQTAFSDLETFYDTIILPPPPRKPKGKATIENHVRFLEIYLVEELKKNTYTS
                     LEALNDATKRIVEDINQRPFQKKSDIRKSRITGFEKYDKPRMNKLPGENYTLCDYKYFL
                     KVPDNYHLEYDAHYYSVLYTQRGKPAILKATMAEIRICDEYNRLICRHPRSYRDFPLYI
                     TDDSHMPQEHLYYKEVNAHDGAYYRRWASVYGDSMVTLIDRILRSPKHEEQAYNSCAGV
                     LHSCKDVPHRLVQEAADKCVEANACKYSYFKKVLGMVQNNHSINNTAASGTLPSHANIR
                     GKEAYK"
     gene            16914..17678
                     /db_xref="GeneID:62696000"
                     /locus_tag="HDCHBGLK_RS08990"
                     /old_locus_tag="HDCHBGLK_01790"
     CDS             16914..17678
                     /codon_start=1
                     /db_xref="GeneID:62696000"
                     /gene_functions="other (smcogs) SMCOG1151: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004605804.1"
                     /locus_tag="HDCHBGLK_RS08990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_01790"
                     /product="ATP-binding protein"
                     /protein_id="WP_004605804.1"
                     /transl_table=11
                     /translation="MRIQSEITLTPEEQALISRLKSFRVPEMARILEEQLRDPNADLNT
                     FKERMSAMINSEWQSRADKRFNRLMKEAHLRYPAADLDETIYRPERQLDTQIIERLSTC
                     HWIEEGKNLIVTGSSASGKTYLINAFCVTAMKQSKSVRYIKANTLMSEMEQARIKATNL
                     DYLNKLTKLDLLVIDDFGLMDLDLDKCRDLFEVLDTRDGRKSTVVISQFPVSSWFDMFA
                     DNTYADACLTRITDKHHTYRLEMNGINMRETE"
     cand_cluster    17954..40592
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    17954..40592
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[27953:30592](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      27954..30592
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="2"
     gene            complement(18213..18539)
                     /db_xref="GeneID:62696001"
                     /locus_tag="HDCHBGLK_RS09000"
     CDS             complement(18213..18539)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:62696001"
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF024949.5"
                     /locus_tag="HDCHBGLK_RS09000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_050755153.1"
                     /transl_table=11
                     /translation="MKTGQRIQEIRKAQGITQNQLAEKLHVSPSFISRIENGSSSLTVD
                     FACEIADALHVARQEIFCDLLINYQTEEVDSISQKIEINIKKFPTQKQDEILAVIEFLA
                     SRLS"
     gene            18670..19239
                     /db_xref="GeneID:62696002"
                     /locus_tag="HDCHBGLK_RS09005"
                     /old_locus_tag="HDCHBGLK_01793"
     CDS             18670..19239
                     /codon_start=1
                     /db_xref="GeneID:62696002"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HDCHBGLK_RS09005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HDCHBGLK_01793"
                     /product="hypothetical protein"
                     /protein_id="WP_004608022.1"
                     /transl_table=11
                     /translation="MFYNKVEVKAIILAVYNIESLGLNSSRILLKSIVWLCKQYETTKE
                     NLYLEKAMWHIYAYLELGYSYETGEREFNIVLEYLQLNRADIFPKREWEYKKITLTKAN
                     VNRLLGKWNPYFQSMKINDAVADIIKKVQDKEYGKYIYHCGKAIEECEENTLWEKTFIL
                     YVTKDEAILQDMNKSKYYMLKEIQHD"
     CDS             19232..19300
                     /gene="allorf_1754275_1754343"
                     /locus_tag="allorf_1754275_1754343"
                     /protein_id="allorf_1754275_1754343"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MIRIATIGGSILGVNRCVFFSS"
     CDS_motif       19232..19261
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MIRIATIGGS"
                     /locus_tag="allorf_1754275_1754343_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       19262..19300
                     /prepeptide="core"
                     /locus_tag="allorf_1754275_1754343_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.10"
                     /molecular_weight="1305.5"
                     /monoisotopic_mass="1304.7"
                     /core_sequence="ILGVNRCVFFSS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MIRIATIGGS"
                     /leader_location="[19231:19261](+)"
                     /alternative_weights="1323.6"
     misc_feature    19508..19525
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: medium, score: 19.86"
                     /tool="antismash"
     misc_feature    complement(19519..19535)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: medium, score: 26.59"
                     /tool="antismash"
     gene            19742..20452
                     /db_xref="GeneID:62696003"
                     /locus_tag="HDCHBGLK_RS09010"
                     /old_locus_tag="HDCHBGLK_01794"
     CDS             19742..20452
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:62696003"
                     /inference="COORDINATES: protein motif:HMM:NF012301.5"
                     /locus_tag="HDCHBGLK_RS09010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_01794"
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="WP_039909930.1"
                     /transl_table=11
                     /translation="MIKIVIIDDEENILNIVENIVKKAMENKIEIYTYLSVKKFWTDFE
                     EKMDFDIVISDVEMPEIGGIELGKRIKGKKSDIYLIYLTSYSMYAVQSYEIEAYQYILK
                     ENMQYRLPIVLSSLINKFEKDKDKFRFIGSPMNKEKIYYKEIIYMCKEKTSKYVRFVTT
                     RGIYKERITLTQIIKELGSAEFLLTERGYVVNVNHLDGIKENLITMDNGEQIIISRSNL
                     KRVKEQINLYRGRL"
     misc_feature    complement(19746..19759)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 23.08"
                     /tool="antismash"
     gene            20462..21772
                     /db_xref="GeneID:62696004"
                     /locus_tag="HDCHBGLK_RS09015"
                     /old_locus_tag="HDCHBGLK_01795"
     CDS             20462..21772
                     /EC_number="2.7.13.3"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:62696004"
                     /inference="COORDINATES: protein motif:HMM:NF025854.5"
                     /locus_tag="HDCHBGLK_RS09015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_01795"
                     /product="sensor histidine kinase"
                     /protein_id="WP_004608020.1"
                     /transl_table=11
                     /translation="MMKMIQMWIAFFEIWLCYQFLYATILEPKLLTKKNRLFVNLNIII
                     VGLLLSINREILFFSYSMMIFCALVICINLFFIVKKNPFLITNLVFLYFLGTSLLDLLF
                     SFWGMIFLQTEFEEAVYWYANSYWKIGILLCTRSITGIIVFSLGKSRDREIDIREFQNI
                     ILSANLVLFVVMRGYQFVLVNMSNGILQMRGDITSFSLLIIIVIVIFVSRAFVKSKMLQ
                     KQNEMLKMREKLKEQSYQELLCVLEQNRQLIHDIKNHMIILQSQERTYDYEGIANYAKE
                     LEKVFLRTTEEIWTGNKVVDLILRQKKYLAEERNIEFFIETIFLPQWPFKDSELCSLFG
                     NLLDNSIEACEKIKKGKRWIKVQVEKQNRLLFLDISNSIEEKILVRGGKLITNKKDKAN
                     HGYGLKGIERIVNKYEGEMSYQVKGNLFKIIITFFLK"
     cand_cluster    20907..42229
                     /candidate_cluster_number="4"
                     /contig_edge="False"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="3"
                     /tool="antismash"
     protocluster    20907..42229
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[30906:32229](+)"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="3"
                     /tool="antismash"
     proto_core      30907..32229
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="3"
     gene            21804..21953
                     /db_xref="GeneID:62697912"
                     /locus_tag="HDCHBGLK_RS18795"
                     /old_locus_tag="HDCHBGLK_01796"
     CDS             21804..21953
                     /codon_start=1
                     /db_xref="GeneID:62697912"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HDCHBGLK_RS18795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HDCHBGLK_01796"
                     /product="hypothetical protein"
                     /protein_id="WP_004608019.1"
                     /transl_table=11
                     /translation="MQEKQEHYLAGDLEVELEEFKSLAQNEEYAEGFLSTTIKCGTFLT
                     IYCC"
     CDS_motif       21804..21893
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MQEKQEHYLAGDLEVELEEFKSLAQNEEYA"
                     /locus_tag="HDCHBGLK_RS18795_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       21894..21953
                     /prepeptide="core"
                     /locus_tag="HDCHBGLK_RS18795_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.60"
                     /molecular_weight="2010.4"
                     /monoisotopic_mass="2009.0"
                     /core_sequence="EGFLSTTIKCGTFLTIYCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MQEKQEHYLAGDLEVELEEFKSLAQNEEYA"
                     /leader_location="[21803:21893](+)"
                     /alternative_weights="2028.4"
                     /alternative_weights="2046.4"
     gene            22019..22465
                     /db_xref="GeneID:62696005"
                     /locus_tag="HDCHBGLK_RS09020"
                     /old_locus_tag="HDCHBGLK_01797"
     CDS             22019..22465
                     /codon_start=1
                     /db_xref="GeneID:62696005"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HDCHBGLK_RS09020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HDCHBGLK_01797"
                     /product="hypothetical protein"
                     /protein_id="WP_039909928.1"
                     /transl_table=11
                     /translation="MEKYSTYLSERKYLSLNEYEIDIYKEIYWKKMLGDTIYEKVLTYQ
                     KNINDYLSGRTFDIETLEVKCEEKLLDYLKKEDDNREGEFRHKIYFKEFFSRVTNYGLT
                     KLKKSVKREVFTAKNLQDFREQLAIQLQTVCIRTLITRLHVNYG"
     gene            complement(22537..22890)
                     /db_xref="GeneID:93982542"
                     /locus_tag="HDCHBGLK_RS19370"
     CDS             complement(22537..22890)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:93982542"
                     /gene_functions="other (smcogs) SMCOG1151: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015526798.1"
                     /locus_tag="HDCHBGLK_RS19370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /protein_id="WP_004608017.1"
                     /transl_table=11
                     /translation="MVCNGYVAGRIAASRGLATFSNLEMQHSPKIFCIFLQKVLAKNSL
                     MDLDLDKCRDLFEVLDTRDGRKSTVVISQFPVSSWFDMFADNTYADACLTRITDKHHTY
                     RLEMNGINMRETE"
     gene            complement(22900..23142)
                     /db_xref="GeneID:62696007"
                     /locus_tag="HDCHBGLK_RS09030"
                     /old_locus_tag="HDCHBGLK_01798"
     CDS             complement(22900..23142)
                     /codon_start=1
                     /db_xref="GeneID:62696007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004605026.1"
                     /locus_tag="HDCHBGLK_RS09030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_01798"
                     /product="hypothetical protein"
                     /protein_id="WP_004604852.1"
                     /transl_table=11
                     /translation="MAKNKKVIKEQKKYQNLQERYEEMNDYLLDLIEDHRCAEEDLRYL
                     NDFIHYKELDEEFRYFREHAHEDENSELPFPYLTL"
     gene            complement(23135..23908)
                     /db_xref="GeneID:62696008"
                     /locus_tag="HDCHBGLK_RS09035"
                     /old_locus_tag="HDCHBGLK_01799"
     CDS             complement(23135..23908)
                     /codon_start=1
                     /db_xref="GeneID:62696008"
                     /gene_functions="other (smcogs) SMCOG1151: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004607446.1"
                     /locus_tag="HDCHBGLK_RS09035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_01799"
                     /product="ATP-binding protein"
                     /protein_id="WP_004605482.1"
                     /transl_table=11
                     /translation="MADIEKSIAACCKQLKLSTNFAGQAFEQKGDTPQEYLLNLLTNEI
                     EYRTAKRKSKFLNTAGFPRRYRVEEFRADEIDFPEDVSFQSLLDLEFYHTGKNVIMYGG
                     TGTGKTMLSILIGMSACNQEIPVRFYRTAGLINLFSESQSSGKLTALKKKLNSARILIL
                     DEFGYVPYDRTGSQLLFDYLSEIHEQKSVILNTNLEFSQWVNVLYDQRMTTALIGRLTH
                     HVELILFPGINNRLRESSINATLSRISSQEAGNNG"
     gene            complement(23901..25433)
                     /db_xref="GeneID:62696009"
                     /gene="istA"
                     /locus_tag="HDCHBGLK_RS09040"
                     /old_locus_tag="HDCHBGLK_01800"
     CDS             complement(23901..25433)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:62696009"
                     /gene="istA"
                     /gene_functions="other (smcogs) SMCOG1213: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004608304.1"
                     /locus_tag="HDCHBGLK_RS09040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_01800"
                     /product="IS21 family transposase"
                     /protein_id="WP_004605483.1"
                     /transl_table=11
                     /translation="MDQIHHIRDMFYRQDKNISEIASETGLNWKTVKKYVDMEDFNNPS
                     PKPASSEVHESKLDPFKPLIDEWLQADKLAPRKQRHTAKRVFKRLKDEADGFGCSYRLV
                     ALYVKQKKEELRLKRTDGYIPLNHHPGEAQSDFGTADFYENDRLHHEAKYLVLSFPYSN
                     GGFLQLNYGENMECLLEGLVAIFEHIGGVPTEIWFDNTRTIVTEIIKGGGRNVTERFQR
                     FCEHYRIKPVFMNPESGWEKGNVENKVGYLRRNELVPVPRFDDLVKENKHLLDRCEIDM
                     QREHYDDDDDRFISKLFEEDKARLLPLPSVPFDTALYTTATTDKYGKFTLDAGKHRYSA
                     SPAFCESIVNLKITSSDVIVMDKDMHEVVRHKRLYGNEHERMDWLPYLTYIARKPRSLR
                     NSGIYDMMPQTMQIYMDNCESKERGRVLKVLAELTERTGFASAVRTVDEAVRLNATDPD
                     SLQSLYRRTYADVPLLPPLENKVLLPQQKVIPFRNDLKMLDAALKKGGVSNG"
     CDS             25504..25662
                     /gene="allorf_1760547_1760705"
                     /locus_tag="allorf_1760547_1760705"
                     /protein_id="allorf_1760547_1760705"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MDIPAMDLFMGMLILGGCHSSATPFLSASSECLATFSNLEMQHSP
                     IPVCNFR"
     CDS_motif       25504..25554
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MDIPAMDLFMGMLILGG"
                     /locus_tag="allorf_1760547_1760705_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       25555..25662
                     /prepeptide="core"
                     /locus_tag="allorf_1760547_1760705_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.10"
                     /molecular_weight="3651.1"
                     /monoisotopic_mass="3648.7"
                     /core_sequence="CHSSATPFLSASSECLATFSNLEMQHSPIPVCNFR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MDIPAMDLFMGMLILGG"
                     /leader_location="[25503:25554](+)"
                     /alternative_weights="3669.1"
                     /alternative_weights="3687.1"
                     /alternative_weights="3705.2"
                     /alternative_weights="3723.2"
                     /alternative_weights="3741.2"
                     /alternative_weights="3759.2"
     misc_feature    25590..25606
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 24.18"
                     /tool="antismash"
     gene            complement(25670..26230)
                     /db_xref="GeneID:62696010"
                     /locus_tag="HDCHBGLK_RS09045"
                     /old_locus_tag="HDCHBGLK_01801"
     CDS             complement(25670..26230)
                     /codon_start=1
                     /db_xref="GeneID:62696010"
                     /gene_functions="other (smcogs) SMCOG1151: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF013828.5"
                     /locus_tag="HDCHBGLK_RS09045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_01801"
                     /product="ATP-binding protein"
                     /protein_id="WP_004608015.1"
                     /transl_table=11
                     /translation="MRIQSEITLTPEEQALISRLKSFRVPEMARILEEQLRDPNADLNT
                     FKERMSAMINSEWQSRADKRFNRLMKEAHLRYPAADLDETIYRPERQLDTQIIERLSTC
                     HWIEEGKNLIVTGSSASGKTYLINAFCVTAMKQSKSVRYIKANTLMSEMEQARIKATNL
                     DYLNKLTKLDLLVIDDFGLMCLL"
     gene            complement(26231..27802)
                     /db_xref="GeneID:62696011"
                     /locus_tag="HDCHBGLK_RS09050"
                     /old_locus_tag="HDCHBGLK_01802"
     CDS             complement(26231..27802)
                     /codon_start=1
                     /db_xref="GeneID:62696011"
                     /gene_functions="other (smcogs) SMCOG1213: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004605805.1"
                     /locus_tag="HDCHBGLK_RS09050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_01802"
                     /product="Mu transposase domain-containing protein"
                     /protein_id="WP_004605805.1"
                     /transl_table=11
                     /translation="MHDYTTIIGVIELRLNKISYDNVQKRYRIGRSGISLIMERYRDSG
                     LSLDDLKQMPAEKVVNLIYPKDNLRHKNIPLPDFHQIHENMIQMGKNADLGFLWIEYKK
                     KNPNGYQLSQFYKLYRDFLVNTYGSTKVSMPVERIPGEKMYIDWVGDQPELLLDPSTGE
                     LKKVHIFATTLGFSSLVYAEAFPDEKLPHFITGTVHALSFYGAVPRYLVPDNLKTAVTR
                     HNKDELVLQTAFSDLETFYDTIILPPPPRKPKGKATIENHVRFLEIYLVEELKKNTYTS
                     LEALNDATKRIVEDINQRPFQKKSDIRKSRITGFEKYDKPRMNKLPGENYTLCDYKYFL
                     KVPDNYHLEYDAHYYSVLYTQRGKPAILKATMAEIRICDEYNRLICRHPRSYRDFPLYI
                     TDDSHMPQEHLYYKEVNAHDGAYYRRWASVYGDSMVTLIDRILRSPKHEEQAYNSCAGV
                     LHSCKDVPHRLVQEAADKCVEANACKYSYFKKVLGMVQNNHSINNTAASGTLPSHANIR
                     GKEAYK"
     gene            27954..30592
                     /db_xref="GeneID:62696012"
                     /gene="lanM"
                     /locus_tag="HDCHBGLK_RS09055"
                     /old_locus_tag="HDCHBGLK_01803"
                     /pseudo=""
     CDS             27954..30592
                     /GO_process="GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0018193 - peptidyl-amino acid modification
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:62696012"
                     /gene="lanM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017000.5"
                     /locus_tag="HDCHBGLK_RS09055"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_01803"
                     /product="type 2 lanthipeptide synthetase LanM"
                     /pseudo=""
                     /sec_met_domain="DUF4135 (E-value: 1.7e-100, bitscore:
                     334.6, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.6e-24, bitscore:
                     84.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHVYKEKEKLRGETPIKEYNYFCEKYVSTFEFVHELFEIYPVLYR
                     IIEEKIENFIKYYIEIFDFFEKDKNKIGEKICGGKLVKRIEEIDFSLSDSHKSGKRVAK
                     LKLDNGMWILYKPRAMKNDEIYMQLIQWISHHIGMKQYEYPFLTYEEHSWTYIVEQSSC
                     NSEKELENYYVRFGIHLFLTYLLGAQDLHYENIIAAGEYPVIIDLEALSGIPRKQKGRS
                     IDEIIYHQLVESVWNTGLLPFCWGTQRRKGVECSGINGKGGQKYLFKIPVVVEGGTSNM
                     HIEYMCPISEEKQNLPKIKEGFIDISHYKAKIKEGFCKAYHIALQRKQELYCWVTKLKN
                     CECRCFMEDTQRYGMLLFSSYHPQLLKDGAEREIFLQAMWDNRNKNDYLIVDSEVKELL
                     RGDIPFFSFHMDSKNLLLGNGGVISNYFMNTPMELLYQKVRLLNIKDMEKQCEYIDISF
                     DILQAPKQQCVNKVYKTCEKKVDCSVVERNNTANSKLVDMYIERLLKYKVFNYDNTEIS
                     WYTIQLEDQYGWSVKTMNIYLYDGLAGMFLISCFLQKYQNTREIAKINKILQSTLFHYT
                     EKGYESMKNLQSQNVGAYEGESSILLTYLIAYQYKKEKIYLDYAKKHIKIIEQLIQMDT
                     NYDVLKGNAGAVLVLLKLYGICPEKKYLVLAEKAVDRLQERALNLEHGVGWEIEKQVPM
                     AGMAHGNSGILMAFVGMWKKTNKSKYFEFAKKY"
     CDS             30691..30828
                     /gene="allorf_1765734_1765871"
                     /locus_tag="allorf_1765734_1765871"
                     /protein_id="allorf_1765734_1765871"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MEGGANMKTPKIVARGWTCVGCAGCTACWASATAISHVSAANIFG
                     "
     CDS_motif       30691..30723
                     /prepeptide="leader"
                     /note="peptide class: sactipeptide"
                     /note="predicted sequence: MEGGANMKTPK"
                     /locus_tag="allorf_1765734_1765871_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       30724..30828
                     /prepeptide="core"
                     /locus_tag="allorf_1765734_1765871_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="26.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="IVARGWTCVGCAGCTACWASATAISHVSAANIFG"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="MEGGANMKTPK"
                     /leader_location="[30690:30723](+)"
     gene            30907..32229
                     /db_xref="GeneID:62696014"
                     /locus_tag="HDCHBGLK_RS09065"
                     /old_locus_tag="HDCHBGLK_01804"
     CDS             30907..32229
                     /codon_start=1
                     /db_xref="GeneID:62696014"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thurincin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF015983.5"
                     /locus_tag="HDCHBGLK_RS09065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_01804"
                     /product="radical SAM/SPASM domain-containing protein"
                     /protein_id="WP_004608012.1"
                     /sec_met_domain="subtilosin (E-value: 2.9e-42, bitscore:
                     142.3, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="Thurincin_rSAM_RRE (E-value: 2e-13,
                     bitscore: 48.0, seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3.5e-06, bitscore: 25.0,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 5.3e-30, bitscore:
                     102.4, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.3e-16, bitscore: 59.2,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 4.4e-07, bitscore:
                     28.0, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.7e-06, bitscore: 26.2,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYLFWDDEILIESINADIICLYVFKGKEVEKRMINNIAKEIIL
                     RINGMHTFDDIVKYFSQKYETSIEEVEGKLVPFLEELEEEYGLSIRTSSHPKEKKVKEK
                     QQNLYPHVASLEITHKCNLKCLHCYGSFDCLNQKSMPIERIKKLLKDLNDIGTWVIELT
                     GGECLIHPQFKEILLYALSLDFVHINILTNGVALTKEIKDIIICNKDRVFVQIDIHSLE
                     DEYLEWFTGAKNIAEIVKSNVRELAGENVKMRIATTVTKRNIDEVEKIADWVYSLGIKM
                     YVPSSVIELGRAVYSEPDILLDQEMQIKLFKTIDRINEKYDGFINTLNSDEFRQSSNCG
                     CLSSHVTIAATGDIKICTMDTGEYTGYQWGNVFEQNIKNIYDEKQSEFIIFSELEAPNA
                     LSEECRECEKRFFCSSCILRGIVAGKEKGEKCKWIKNMPFV"
     aSDomain        31006..31173
                     /aSDomain="Thurincin_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a thurincin
                     sactipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_HDCHBGLK_RS09065_Thurincin_rSAM_RRE.1
                     "
                     /evalue="1.50E-15"
                     /identifier="RREFam019.1"
                     /label="HDCHBGLK_RS09065"
                     /locus_tag="HDCHBGLK_RS09065"
                     /protein_end="89"
                     /protein_start="33"
                     /score="48.0"
                     /tool="antismash"
                     /translation="RMINNIAKEIILRINGMHTFDDIVKYFSQKYETSIEEVEGKLVPF
                     LEELEEEYGLS"
     gene            32272..32976
                     /db_xref="GeneID:62696015"
                     /locus_tag="HDCHBGLK_RS09070"
                     /old_locus_tag="HDCHBGLK_01805"
     CDS             32272..32976
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:62696015"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004608011.1"
                     /locus_tag="HDCHBGLK_RS09070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_01805"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_050755152.1"
                     /transl_table=11
                     /translation="MLSVKNLKKEYDKFKIDKVSFSVERGKITGLIGNNGAGKTTVLKC
                     VIGVLQYDFGEIIIDGLMLEHHEEEYKEKIGIVFDSGYFYENLTLEEMKKIISAAYQNW
                     DEEVYQGYLKKYKLDSKQKIETLSQGMKMKYALALALSHNAEILIFDEPTSGLDPKTRQ
                     LFCEEMIDQKKHGRTILFSTHITSDLDKIGDNIILMDRGRILKEATKQEFLMGEPTVEA
                     AMVNLITEGGKA"
     gene            32973..33623
                     /db_xref="GeneID:62696016"
                     /locus_tag="HDCHBGLK_RS09075"
                     /old_locus_tag="HDCHBGLK_01806"
     CDS             32973..33623
                     /codon_start=1
                     /db_xref="GeneID:62696016"
                     /inference="COORDINATES: protein motif:HMM:NF024741.5"
                     /locus_tag="HDCHBGLK_RS09075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_01806"
                     /product="ABC-2 transporter permease"
                     /protein_id="WP_004608010.1"
                     /transl_table=11
                     /translation="MKILTLIEKEIKLAGNYFWLSIMVLIGIPIFLNQQSGGQYSGIYT
                     LMIALNFSIYFLFNNIFLNEDKYKGNLYMLALPFGKNRLVLAKYILAILMFIFAIICYK
                     GMASVGVYLNIVFSQLNYSEMSIVFFVFSLIIGIFFPIYYKFSYAKIKVLLAAIMIFLP
                     TWGLVILKYILDIEVVYQKIVISTRALISINILSIIVMLCSVSISIKCLNSKN"
     gene            33655..34515
                     /db_xref="GeneID:62696017"
                     /locus_tag="HDCHBGLK_RS09080"
                     /old_locus_tag="HDCHBGLK_01807"
     CDS             33655..34515
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:62696017"
                     /inference="COORDINATES: protein motif:HMM:NF014244.5"
                     /locus_tag="HDCHBGLK_RS09080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_01807"
                     /product="site-2 protease family protein"
                     /protein_id="WP_004608009.1"
                     /transl_table=11
                     /translation="MKKSNIKKRIYQIVGITIYICIILLVGKMTRSFLQEFKYEMGEFN
                     IATLGSFIGAYVVCVLVHELAHLISFLLMGFPVVAAEICGILLLFSHRKIKVKINFSRI
                     MLGGWILPVVKKNIVSLKQYKHYKRGFSFALIMGPVVSCVLMVFSLLINIKLKNDDIWY
                     RQFFFLLFFFSAGFVISSVLKKGNSRGDIYSFFLIQKRKIFFLVQMCENIDMEKEKNIY
                     KISNCLIKELEKELQFQAKKNSNILEVFFASTFWRKMQNIFGECCISKLEKVARPRLAA
                     ILPAT"
     gene            complement(34539..34781)
                     /db_xref="GeneID:62696018"
                     /locus_tag="HDCHBGLK_RS09085"
                     /old_locus_tag="HDCHBGLK_01808"
     CDS             complement(34539..34781)
                     /codon_start=1
                     /db_xref="GeneID:62696018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004605026.1"
                     /locus_tag="HDCHBGLK_RS09085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_01808"
                     /product="hypothetical protein"
                     /protein_id="WP_004604852.1"
                     /transl_table=11
                     /translation="MAKNKKVIKEQKKYQNLQERYEEMNDYLLDLIEDHRCAEEDLRYL
                     NDFIHYKELDEEFRYFREHAHEDENSELPFPYLTL"
     gene            complement(34774..35547)
                     /db_xref="GeneID:62696019"
                     /locus_tag="HDCHBGLK_RS09090"
                     /old_locus_tag="HDCHBGLK_01809"
     CDS             complement(34774..35547)
                     /codon_start=1
                     /db_xref="GeneID:62696019"
                     /gene_functions="other (smcogs) SMCOG1151: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004607446.1"
                     /locus_tag="HDCHBGLK_RS09090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_01809"
                     /product="ATP-binding protein"
                     /protein_id="WP_004605482.1"
                     /transl_table=11
                     /translation="MADIEKSIAACCKQLKLSTNFAGQAFEQKGDTPQEYLLNLLTNEI
                     EYRTAKRKSKFLNTAGFPRRYRVEEFRADEIDFPEDVSFQSLLDLEFYHTGKNVIMYGG
                     TGTGKTMLSILIGMSACNQEIPVRFYRTAGLINLFSESQSSGKLTALKKKLNSARILIL
                     DEFGYVPYDRTGSQLLFDYLSEIHEQKSVILNTNLEFSQWVNVLYDQRMTTALIGRLTH
                     HVELILFPGINNRLRESSINATLSRISSQEAGNNG"
     gene            complement(35540..37072)
                     /db_xref="GeneID:62696020"
                     /gene="istA"
                     /locus_tag="HDCHBGLK_RS09095"
                     /old_locus_tag="HDCHBGLK_01810"
     CDS             complement(35540..37072)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:62696020"
                     /gene="istA"
                     /gene_functions="other (smcogs) SMCOG1213: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004608304.1"
                     /locus_tag="HDCHBGLK_RS09095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_01810"
                     /product="IS21 family transposase"
                     /protein_id="WP_130574654.1"
                     /transl_table=11
                     /translation="MDQIHHIRDMFYRQDKNISEIASETGLNWKTVKKYVDMEDFNNPS
                     PKPASSEVHESKLDPFKPLIDEWLQADKLAPRKQRHTAKRVFKRLKDEADGFGCSYRLV
                     ALYVKQKKEELRLKRTDGYIPLNHHPGEAQSDFGTADFYENDRLHHEAKYLVLSFPYSN
                     GGFLQLNYGENMECLLEGLVAIFEHIGGVPTEIWFDNTRTIVTEIIKGGGRNVTERFQR
                     FCEHYRIKPVFMNPESGWEKGNVENKVGYLRRNELVPAPRFDDLVKENKHLLDRCEIDM
                     QREHYDDDDDRFISKLFEEDKARLLPLPSVPFDTALYTTATTDKYGKFTLDAGKHRYSA
                     SPAFCESIVNLKITSSDVIVMDKDMHEVVRHKRLYGNEHERMDWLPYLTYIARKPRSLR
                     NSGIYDMMPQTMQIYMDKCESKERGRVLKVLAELTERTGFASAVRTVDEAVRLNATDPD
                     SLQSLYRRTYADVPLLPPLENKVLLPQQKVIPFRNDLKMLDAALKKGGVSNG"
     CDS             37143..37301
                     /gene="allorf_1772186_1772344"
                     /locus_tag="allorf_1772186_1772344"
                     /protein_id="allorf_1772186_1772344"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MDIPAMDLFMGMLILGGCHSSATPFLSASSECLATFSNLEMQHSP
                     IPVCNFR"
     CDS_motif       37143..37193
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MDIPAMDLFMGMLILGG"
                     /locus_tag="allorf_1772186_1772344_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       37194..37301
                     /prepeptide="core"
                     /locus_tag="allorf_1772186_1772344_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.10"
                     /molecular_weight="3651.1"
                     /monoisotopic_mass="3648.7"
                     /core_sequence="CHSSATPFLSASSECLATFSNLEMQHSPIPVCNFR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MDIPAMDLFMGMLILGG"
                     /leader_location="[37142:37193](+)"
                     /alternative_weights="3669.1"
                     /alternative_weights="3687.1"
                     /alternative_weights="3705.2"
                     /alternative_weights="3723.2"
                     /alternative_weights="3741.2"
                     /alternative_weights="3759.2"
     misc_feature    37229..37245
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 24.18"
                     /tool="antismash"
     gene            37337..37756
                     /db_xref="GeneID:62696021"
                     /locus_tag="HDCHBGLK_RS09100"
     CDS             37337..37756
                     /codon_start=1
                     /db_xref="GeneID:62696021"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HDCHBGLK_RS09100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_039909925.1"
                     /transl_table=11
                     /translation="MVSAINIILMRYIICGDIIDSSTKELFEYCINTLETDKIRFMEEE
                     CKILFIHLIYYLKYEDDHRWETLIPYAINIFDDDGVNQYYKAQIKQICYLENNLEFLNE
                     RENIKTSSFWEIEHLLNIQQQDERNLLKIFCESIN"
     gene            complement(<37826..38128)
                     /db_xref="GeneID:62696022"
                     /gene="tnpA"
                     /locus_tag="HDCHBGLK_RS09105"
                     /pseudo=""
     CDS             complement(<37826..38128)
                     /codon_start=1
                     /db_xref="GeneID:62696022"
                     /gene="tnpA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612901.1"
                     /locus_tag="HDCHBGLK_RS09105"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="IS66 family insertion sequence element accessory
                     protein TnpA"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSNVAIFCTYRIPAEEQYRLIMECRQSGLTDHQWCAEHDIKPGTF
                     YNWVKRLRQKGCMDLPAATGRSYNTPESQEVVRVDFHNPDTISYEQPLDMIPASME"
     gene            complement(38176..39792)
                     /db_xref="GeneID:62696023"
                     /locus_tag="HDCHBGLK_RS09110"
                     /old_locus_tag="HDCHBGLK_01811"
     CDS             complement(38176..39792)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:62696023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004608003.1"
                     /locus_tag="HDCHBGLK_RS09110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_01811"
                     /product="IS66-like element ISCsc1 family transposase"
                     /protein_id="WP_004608003.1"
                     /transl_table=11
                     /translation="MAGNSKDSKILAYKDMINQLNKTIAAQTELIQSLQKTLEADRLEK
                     ETLRQQIEYLTKKLFGTSSEKRKDIEGQLNLFDEAEQEADPAWNPELPDGIIVPEHKRK
                     ARRTHAELFKNVPSCDEIISLPEEERNCPACGTQMECIGKEFVRHEFRFTPAKGKVVNI
                     YRETYKCPECAISAEHPDDQTFVKAPVQEPLIPESYASESVVAWAMHQKYQNGLPLNRQ
                     EEDWKQLGVPLNRATLANWIIYCTENYLRHVYDYFHRQLLVRKYLMADETRVQVLNEPE
                     RNPETDSWMWLFRSGEDGLPPILLYHYTETRAKFHAESFLQGFSGYLETDGYQGHHNLP
                     DIKRCSCWAHVRRYFTDAIPKGKEYNYSLPAVQGVQFCSKLFDCERYSKAKNHTAEQRK
                     QFRLEKEKPILDVFWDWLDQQHPNKGTRLAKAVNYAQNRKDTLMTYLEDGHCSFSNNLS
                     ENAIRPFTVGRKNWLFSASPKGATASAIVYTMVEMAKANDLNTYKYLTYLLSQRPNDKM
                     SDEQLEQFAPWSKAAKANCQN"
     gene            complement(39943..40287)
                     /db_xref="GeneID:62696024"
                     /gene="tnpB"
                     /locus_tag="HDCHBGLK_RS09115"
                     /old_locus_tag="HDCHBGLK_01812"
     CDS             complement(39943..40287)
                     /codon_start=1
                     /db_xref="GeneID:62696024"
                     /gene="tnpB"
                     /inference="COORDINATES: protein motif:HMM:NF017528.5"
                     /locus_tag="HDCHBGLK_RS09115"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_01812"
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="WP_004608002.1"
                     /transl_table=11
                     /translation="MLGDITVADEIYIVTGRTDMRKSIDGLCAIVEEQLHMDPRRSALY
                     LFCGRRCDRIKALLWESDGFVLLYKRMEVQGRFRWPKNQLEVKQLTWQQFDWLMSGLEI
                     EQPKAFKPTE"
     gene            complement(40281..40694)
                     /db_xref="GeneID:62696025"
                     /gene="tnpA"
                     /locus_tag="HDCHBGLK_RS09120"
                     /old_locus_tag="HDCHBGLK_01813"
     CDS             complement(40281..40694)
                     /codon_start=1
                     /db_xref="GeneID:62696025"
                     /gene="tnpA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016440718.1"
                     /locus_tag="HDCHBGLK_RS09120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HDCHBGLK_01813"
                     /product="IS66 family insertion sequence element accessory
                     protein TnpA"
                     /protein_id="WP_039909923.1"
                     /transl_table=11
                     /translation="MRSKRIPAEEQYRLIMECRQSGLTDHQWCAEHDIKPGTFYNWVKR
                     LRQKGCMDLPAATGRSYNTPESQEVVRVDFHNPDTISYEQPLDMIPASMERSSISEAAP
                     MKLSVGRFLLTIPNGTDPQLLAQTLRIVKELEC"
     misc_feature    41313..41327
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 22.38"
                     /tool="antismash"
ORIGIN
        1 aatcaggaaa gagaaaaaag ggaagagaaa gggatgccgg gataggcgct atggctgtcc
       61 ggaatatcac ccgtgataag aagcaggcgg tagtcatcta cgcttctttt attgtggcag
      121 tgaccgtctt tctcattatg aatgtcgtgg taaaggagaa tgatgccaag tctatcttga
      181 atgccactta caattatgac atacgattca agaatgagac tacgttggat gaccaaaagc
      241 ccttgcttac gaaagaaaag atccaggcaa tctgcaagat aagcggggtt aagagcgtag
      301 aaagcgtgac atccacagaa gcggttgttc cataccagaa agaggtctat ggagaattct
      361 ataaagaact gtaccagtct agatacacgc cgggcggaga ttatgaagaa gatatggaat
      421 cctaccaaaa taatcctgca ggcagccggt ttacgacgcg gcttgtaggg attgaccaga
      481 cggaatttca aagaataaat aaggaactgg ggaatgtgct ggatgaagag gaattccggg
      541 aaggaaagat cacaatttta gaagactttc tgcagattga tatgggcgat gtgatcggaa
      601 agacggttgc gttcaccctc ccggacggcc ttcggccaag ccaggaggag aaagtgcgga
      661 ttgcggcaat cagccaagac tcccctgctt atttcgccgg gggctataat ccggtcatga
      721 tggtgagcca ggagtatatg aacaccctca tgggagagcc attctgcgaa ctgattcagg
      781 taacatatga cgagacattt tccgggaaaa cggagaaaga agtgaaacaa gtatttgaag
      841 gtgagaagca gattacctat gattcaaaac tggaacgcta ttcagaaatg aaaagaacag
      901 agatacaggt aaaggtattg ggaaacagtg ttgcggctat tatggcgctg ctggccgcgc
      961 ttaactactt taatatgatg gccgccagcg tgcagaaccg ttccagggaa tttgccacgt
     1021 tagaaagcat tggaatgaca tctgggcaga tcaggaaaat gctggtcctg gaagggagcg
     1081 gatatgcagt ggtatcgatc atcatatccg ttatcctggg gcttccttta agtcatgccg
     1141 tgtttgaggg aatgaatatc tacaggattg actattccat gccatggcca ggcaatctcc
     1201 ttttgtttgc cggaatcctt attctgtgca tgaccgttcc ggcggccatc tatcagcgga
     1261 cgcaaaaaaa cagtatcatc gagcggcttt tgtgctaaga tatagtcaag cataacagga
     1321 ggaggattac agatgatcag aatagaaaaa gaaagatgta ttggctgcgg cgcatgtata
     1381 aaggactgcc ctgcatcggc aatcaggatg acggaagaaa aggcggaggc gtataaagac
     1441 tgcctgctct gcggtcactg cgtcgccata tgcccgtcgg aggcagtctc tatcccggag
     1501 tacgatatgg aagatgtaga agcatatgac aaagacacat ttacgctgaa agcggaacat
     1561 tatcttcatg cggtaaagtt ccgcagaagc atccgcaact tcaagccgga aaagattgag
     1621 cgcgagaagg cagaaaggat actaaaggcc ggccgctata ctgccaccgc caagaaccgg
     1681 caggcgtgta catacgtatt tatccaggag cagctagacg agttcaagga acttgtctgg
     1741 aaggaaatgc cgtctatatt ggaggaactc aagcaaaatg ccccggatta cgccagagca
     1801 ttcgaactct tttacctaaa atggaagcgg aaccccaagg acgatacgtt ctttttcaat
     1861 acgcccgcct ttcttgtcat cgcctccaat aatcctttag atggagggct ggcggcagcc
     1921 aacatagaga acatggctgt ggcggaagga cttggcgcgc tgtacagcgg ctatatgatg
     1981 cgggtgatag gattaagcca gacgctgcgg gaatggcttg gaatagggga gaagagagta
     2041 tcctgctgca tgctcctggg ctatcccgct gtatcataca gaaggacagc acccaggaaa
     2101 tatgcagata ttctctggaa atagatagaa tctatatcca tcagccttag aattacagaa
     2161 gccggaatgc ctgttctaca gaagcgcgca tattctcccg ggcgcgctcc ggcttcatgg
     2221 cttcctcaag cgtggtaacg ccgcggacga tggggaagaa cgcgtcaata ccagcctgat
     2281 tgcaggaggc agcgtccttg gttacgcttc cggcaaaggc aaggactttc acgttatact
     2341 ttttggccag cctggcaact ccgacaggag cctttcccat ggcggtctga tgatccagac
     2401 ggccttctcc ggtgacggcc acatccgcgt ctcttaactc ttcttccaac cccacagcgt
     2461 ccagaatcag gtcgattccc ggggtaagtc ttgcattcag gaaactcagg aaggcaaagc
     2521 caaggccgcc ggctgctccg gcgccttctg tttctgcata actgcagccg aaggtatcgg
     2581 cggttatctg cgcatagtgg gtcattgcct gatccagggc gtctttctgt tcctcagtca
     2641 cgcctttttg agacccatag atgtaggttg cgccgctctt gccgcagagc gggtttgtta
     2701 cgtcacatgc tacctggaag gtgcattcgg ccagcctcgg atttttttta gcgctgttga
     2761 tggcagcaac tttggagagc gcctgcgcac cttcgcccac atcatttccc tgactgtcga
     2821 gaaagacgaa cccaagggcc ttaagcatgc cgatgccgcc gtcattggtg gcgcttccgc
     2881 cgattccgat tataaagttc cggcatccct ttgtgatagc atcgttgatc atctcgccta
     2941 cgccgtaggt ggtggcagac aaggggtcct gcctgtccgt gggaacaagc gtgattccgg
     3001 cggcagaagc catctcgatg atggcggttt tcgtttcttc caagtatccg taatatgcat
     3061 gaacctttgt tcccataggc ccggtgatcg taagatcgac gcgctcgcct ttcattcctt
     3121 cgatcaaggc atccgtggtg ccctctccac cgtcagccag gggctttaca atgacttttg
     3181 catccggctt ggcggcaagg attccctcct cgactgcaat accggcttcc atggaagtca
     3241 ggcttccttt taaggaatcc attgctacaa caactttcat ttctttgaac ctcccgtgtc
     3301 tgttatccat ttcgttactt tgttaaggcg agtatagcac attagagtca aatggaaaat
     3361 gttccttggg acaaaaataa gccgatttag ttgcgaaata tgttatatag gacaatattc
     3421 ccgcgaacac tcatccaggt atcgtatact caaatccgct gatccggtgg atgcggtcaa
     3481 gtttatactg cagcgtattt agtaccataa aagtgtagtt gttagagagt aattaactct
     3541 gacatctgca cttattttat tataataagg ggagtaattg gtctaacgtc ggcttttttg
     3601 gattgccaca tccgtcacaa aaaccgttaa ccaacctctt attataagca ttcgattaag
     3661 caggtaggga ttcgctcccg cgtaaccaac taaactgaat ggtaataagt gtagctggga
     3721 caattactaa aacagttaga ggaggttctg gatgataagc gtaggaattg atgtatccaa
     3781 gggaaaaagt acagtctgca tactgaagcc gtatggagag attatgtgta gtccttttga
     3841 gatgctgcat ggggagaagg agctgaatgc tctcgatgat ctgctaaata agctagatgg
     3901 ggagataagg atcgtgatgg aggctacagg aatttatcat ttgcctatat tgacattctt
     3961 tcacgaaaaa ggatatttcg tatctgttat taatccattc gcaatgaaga aatatgcaaa
     4021 ggacaacagt attcgaggtg caaaaacaga caaacttgat tcaataatga ttgcaaatta
     4081 cggaatcgag aaatggttca aattacaaag atataaaggt gatgaagaaa tttatgcaga
     4141 gcttaaactt ttaggtcgca ggtatcgaca ctatatggaa cttcacgtga aagcattgca
     4201 ggaattgacg catatcctgg attatgtgat gcctggtatt aagaagatgt ttaacagttg
     4261 gaatgaagct aatggcaagg acaagctcag cgactttgtg gagcaatttt ggcattttga
     4321 tctaatcaca gccatgagcc ttgaaaaatt cacagaggag tatcttgact gggcaaaaga
     4381 aaagaaatac caccgaagca gatccaaggc tgaagcagtc tatgaattag cttccaatgg
     4441 tatttccaca ctgtcttccg gtaccccatc gaccaaaatg ttagtacagg aagcgatatc
     4501 ggtattgaga actgtagata gttctctgtt tctcatttta acacgaatgc aagaacttgc
     4561 gaagaccctg ccggaatatt caacggtcag agaaatgggc ggagtaggtg atgtccttgc
     4621 agttaaactg attgcagaga ttggcgatat aagaagactg cacagcgcaa aggcactcat
     4681 agcatgggct ggaatcgacc cgccgccgta tgaatcggga cagtttattg gttcaaaacg
     4741 caagataacg aaacgaggtt cttcaacgct caggaaggtc ggatatgagg tgatgagagt
     4801 ccttaagagt catcctgctc caaaagatga tgctgtatac aactatattt tgaaaaagga
     4861 aagtgaaggt aaaagcaaga aacatgcaaa gattgcaggg ttgaataaat ttctgcggat
     4921 ttattatgca agagtaatgg ctgtttatca atagaacata aaatccgcga gttcgtacag
     4981 gctggagcac agagccagcc tttttgtcat acccaaaaat agattagtta aataatttaa
     5041 aaaacctgcc aaaaaatact tgacttttgt tagcaggttt ttgtgaagaa atagtttctc
     5101 gcttgtctgt aacatggacc gcgttttagc cagaaacgct tccttgcttc tgtgctgagg
     5161 atcggcagaa cgtgggagtc tatggtgtaa cagcagctgg aaaatcctat tttctgcctg
     5221 cctgctgtgt ggaagcctgc aggctgaatt atcgctgtaa attcgtagac tattgtgatc
     5281 tgttggatga attgattgtt cttaatcgtc tggaagatct gagccgttac agaaaacgga
     5341 ttcggtatta tgccagaata cagcttctgt ttatatatga ctttgcaatc agtcgttact
     5401 ctgaggaata acaactggtt atatagttct tatagagcgc tcatagccag tataaattta
     5461 tccagaggag caaaatacgc ttctctggaa taaaagaaag cgaccgttga agatggccct
     5521 gagtggccgc taaatacggc tatttgcatt tttctgtaat gctgttgact ttgttgtatg
     5581 aaatgagtat aatatggtta gaatattact accactaatt caaggaggtg tcgttatgaa
     5641 tattcgtcca tccgcagcaa tcagacagaa ttacaacgag attgccgata tgtgcagaaa
     5701 aaccgcagag ccgattttcc ttaccaagaa tggcgaggga gatttggttg ttatggatat
     5761 tgaaacctat aaccgcaggg aaaagatgtt aaaactccgt gaggaattgc ttgcggttga
     5821 ggaggacagg atgcacggca gcacgggata ttctgtcggg gaagtcgctg ccatgatgcg
     5881 tagtgcaatc aaggaggcgg caggccatgg aaaaacagaa taggtatcgt gttatcgtgt
     5941 cagaacgggc gacacagatg cttgtttctc atgctgcatt tctggcgcaa gtcagtccag
     6001 aagaggcaga aaggctgacg gcagaatttg aaaagacagc aaattcacta gaaaccatgc
     6061 cgcagagatg tccgtggctc acaggggaat atatcccaag aaacgcctat cgctttatcc
     6121 tgtttgagaa acggtatatg ataatcttcc aaatcgtaga tgatattgtc tatgcggatt
     6181 atgtagtgga ttgcaggcag gattacagtt ggctcatacg gtaacaacag aataaccaga
     6241 acggaaatcg tcacttaaaa caggtggcga tttttcttat aggaaattcc gattttaagg
     6301 aatagaaaaa aaggacaaga gtttaccgaa tatatgttag ataaactctt gtctgggtat
     6361 gacgatgaga cgacacggct tagaagatat aaaaaccttc cacgccagcc tcgtcatcaa
     6421 ataagtcgtc ttcatttaag aaataatcct gtgcacttgt attgccaatg cctgttatat
     6481 cctggattgt acttatttgt atggatagaa acagaagcac tattatacga atgtttttaa
     6541 gagttatcaa acaaattaaa ttaatggatt tttaaaaaat tgaaagaata ttctaaatat
     6601 tatatacttt tattgcaaat tattgtataa tatctcatat attaaaatga ggggcgtgat
     6661 atgtatggca aaatagaact ggaagaactg gaatgtgata agaaactata aacttactaa
     6721 gtctttcatt taaacccgat attggaagaa aggcgtgcat atgcgtaaga aagtatttag
     6781 aattttatgt atcatttttt cggcaggggt ttttatgtct gttttttatc cgtggacggt
     6841 gctgaatggt gaaagctata ctattataga gttctataaa caagcagttt ttgacaaaca
     6901 attatatacc atggcagata tgggaggaag cgtttatctt cttctgatat ttttgatttt
     6961 tcctatggtg gtagggattc tttctggagt caaagcagta ttgctggtat tcaggaaaaa
     7021 ttactatttg ttgggagaaa tcattaatat atcagaattg atcagcgttg ccgccttttt
     7081 tgcatttcaa ggatatgaat tgttaacagc tccttttttt caagcaattt ttgtatttct
     7141 tgaatttatg atggaatgct atttgtcgga tgttgatcgt tttactaatg aatgggaaat
     7201 tcataagatt aaaaatcgga cggaaaaaga agagaggaaa cagagacttg catttcccgg
     7261 gaattatgat agaaggttac gaaaaattat tcgaaaagat gcattacatc cttcgaaggc
     7321 ggttgtttta gtatgcatcg gtaatggaat ccttctcggg tcagcatttg ctttatttgc
     7381 agtgaaagaa caatttcaga aaaactatag cgcaaaggct gttcttccta cggaggggct
     7441 aaatggaatt ttgaccaatg gacttctggt tattactatt ttttatatct tttttgcaat
     7501 agcagcattt tttaattatg tccataatca tcaagaaaga agaaatttgt tctggacttt
     7561 gggaagtaga gaaagactta atagtattgc atggaaaatg gaatatgagt ttatgattgt
     7621 attgtcaatg attccgggct atatcattgg tgtaggaatt tacaatctat taagggtgat
     7681 gttgaaaaag gaacttggtg tattgataga tggaaggact caacttcagc tttacttttt
     7741 atcaggatta ttatatctgt gtttatcggg agtaattatt tggctttcat caattttgtt
     7801 gcgaaaggaa ttgcggggag aaaaaagaaa tatcaggaaa ctttcgactc ctacgaaagg
     7861 tgttgctgta attacggtta tgctatcgtt aggctatctg gtcttttcta tcggaagata
     7921 tatgcagaga agaaatgggg aaagtttaaa catctttgtg tatggtatta tattaggtgg
     7981 tatatgcgtt ttatgttcca ttcgactttt ggagagtttg aatagaagag gaaaagcgca
     8041 aaactttcaa gtacttttag ataaaattcc tatgcaaagc ggttttttta aagaagcagg
     8101 ccttcaatct gtggtttttg ctttccattt tattttctta ggatttttgt ctgtaactat
     8161 ggccggaaaa ctttcagcac cttcaccgga cacattgttt ccgcatgagt atgtttgtat
     8221 ggcgtatcca gaagatgaag aattattcac agaattgaga gataaaaatc tggcagatgt
     8281 aaagtcatat ccgatgatca gggttacatc cgtacaggga aatcctacgg attggatcga
     8341 tattgctaat aactattatc gtaaaattat ctggcctcag ggacagcata taggaatctc
     8401 cagaagtact tatgaaagct tatgtacaga tgaaaaaaag aatatatcca acttcacatt
     8461 gtctgaagat gaaatttatg tagtttatca ggaagattgt tctgtaaagg cccatccttt
     8521 ggagtggtat atgaatagaa ggacaccttt tatcaaagaa gggcagccgc ttcgttggta
     8581 taatcctttt gctagagaaa attattatcc gccaagaaaa gtgattgggc aggagagaaa
     8641 agttttaacg ggagtatttg aaagaggaat ccaagaacat attgttgtat tttcagacga
     8701 ttactttaat cagctgcatg atgtggacgg gccatccgtt ttgtacttcg ttgattgtct
     8761 agagaaaaac aaaaaagaag tagagaaagt actttctgtt tttgcatcta ggcatatgga
     8821 agattcctca tgggatcgtt taattcaacc ttattacagc aaaacagaaa agattacaga
     8881 tatggaagca gagaggaaat tagaacaaat atcaacttcg atagagatgt tattatcagt
     8941 tttttgtgta tttattttct gttttataaa aatagaattt gaacaggaag agaaacaaaa
     9001 gagatttcag acattatttt gtctcggaat gcataaaaaa caagtcaaac acagtctatg
     9061 gagagaaatt tgtcggttta tatcgctgcc attgattttt gcatatactc ttgcaactgt
     9121 agttgtaact tttatatgga aaatgcgatt tgtaacggga gcagaaagta gaaaactctg
     9181 gatgactctt attattattt ggacaatata tcttttgttg caaatgctgt taactttcgt
     9241 attgtaccgg tatcaattaa ataatttgaa tctgaaaaat ggcgtgaggg ggagaagaag
     9301 atgaagattg aattgaaaga catcaaaaaa tcatatcaaa ttcccggaca agatgaattt
     9361 aaagtattga aaggaatcaa ttttttaatt tctcagggag aatatatttc aattatcgga
     9421 cgctctggtt gcggaaaaac tactttatta aaaatagttg gtttattgga cataccaacc
     9481 gaaggagatg taattattga tggcgtaaaa gaaaaagaat tgtggaatga tgaattggca
     9541 gatcttcgta gaagaaaact tggatttata tttcaagact attttctttt ggaacatctc
     9601 acggtacttg ataatatgat tttgccagct cttttggata aggcagagga gaaaaagtca
     9661 ttagagcgtg cggaagaatt agcaaattat ttacagattg acaataggct attgcttaaa
     9721 taccctaaag aactttcagg tggcgagaag caaagggtcg caattgcaag ggcgctgttt
     9781 aatgatccgg atatcctttt ggcggatgag ccctcaggga atctggacga acagtctaag
     9841 aaaaatgtag aaaaaatatt taaagatctc catgaaaata taaataagtc aattctttta
     9901 gtgacacatg atttggaatt tgccaagtgg agtgaaaaat gttatcagtt acaaaacggg
     9961 gtgttggtta aaggataaat ataaataagg agataagaat gtgatagaaa agccatttat
    10021 tcacttgttt aaaactacaa aaggtcaata ttgttatgat gttaataaag atgaaatcat
    10081 acaattgcca gatgatgttt atatgtattt agctgggaaa ggagaaaaaa cagattatgt
    10141 aaaaacttat atagaacagt tgtacgaaag gggctattta aagtcaaaac gagttataac
    10201 aactaaacat cctgcaaccg attacttgtc ttattattat gacacaaaat taaatttctt
    10261 aattttacaa gtaacacaaa attgtaattt gagatgtgaa tattgcgtgt attccggaaa
    10321 ttatcgaaca cggtctcaca acaataaaag gatgtcattg atttagctca aaaaggaata
    10381 gattttttgt atcaacattc tagagaaagt acaagaatta taattggatt ttatggaggc
    10441 gaacctttat taaaatttga tttaatcaaa aaatgtgctt tttatataga aaaattgttt
    10501 tatggggaaa aaagtaatat ttacaattac aacaaacgca acattattaa aagagtctat
    10561 tgtagaattt tttgtagaaa aaattaatgg agaatttaag atataagaaa acattattgt
    10621 caattttata aaaataatat tagttttaat acaagtatga aaaagaattt tttgattggt
    10681 tgatagaaaa ttatgattgt gctacactaa attcaagcag atattttttt tgaaaaaaga
    10741 aagaagtgat taagatgtgc ataaatgaaa aaaggaaaaa tgatgttttc ctccatgcaa
    10801 agccagtaga ttgcgacatt tgcatggagt aatcatagtc gcagaataga aatgctggct
    10861 ttgctacttg actatcacat caaggaggaa agtccgcatg aagtatttta atgcaaaact
    10921 gattcttcca gacgcattgg taaaagaatt acagaattat gttcaaggtg gatatatcta
    10981 tgttcctatc gaacaggagc agcaaaagcg ttggggagaa gtttccggct atcggcaaga
    11041 attggaacaa cggaatgagc aaataaaaag agagtatcag aatggcattt ctatggaatg
    11101 cctgtctgaa aaatatggtt tatctttcta tgctgttcgg aaaattatat atcagaaata
    11161 accgtaaggg gctgtgtttt acagcctctt attttataca gattggtttg tactgtatgg
    11221 tgtatagaat ctctaccata atggcgataa aataaaagaa agacataaga tagttttatg
    11281 aaaggtgaat gttatgtgta ctagatttgt ttatcgtgga gatgatatga ttacagggtt
    11341 caatcttgat attgacctct ctgtatggaa acataaagtg attgaagaaa aggagcgttt
    11401 ctatatcgga attttgcgac cagatggaac gtatcattct tatcatggag ttaataaaaa
    11461 tggaaatgtt gggacgttat tatatgtaca tggaaaccct gccggagcat atcaagactg
    11521 cccaaactgt atgacgattg cagatttgac ggagcagttt atcaaagcac agatttcttt
    11581 tgatgaagtg cttcaaattt taaagtcaaa gaggattacc tatgcgccgg acgctactat
    11641 gcaggcgatg ttatcagatg tttatggacg cgtgttgata atcgagccgg ggattggata
    11701 ttgggaagaa cataaaagat attccttaat aacgaattac tctttgatga atccggaaag
    11761 tacaaaaaat tttattgtgc agggcgataa ccgatacgaa agagctttgc aattattaga
    11821 cagctataaa aatgattttt caatctctga cgcatttgca ttgcttcata ctgttcggca
    11881 agagggtgaa tgggctacta gagtttcatt tgtttactct gtgaaagaac aggcagtatg
    11941 gtatgcagag aataaccact ttgaacatat tacaaagttt gtgtttccgt cagagcagca
    12001 ggaaaggagt agtcatgcag cagaaaatct atcctcgttc aaaggataaa gaaacggttt
    12061 atctgcaaaa tgttattacc aatcctaata tcatagttgg agattatacg atatataacg
    12121 attttgtcag agaaccaaga gattttgaaa agaacaatgt tttgtaccaa tatccagtta
    12181 ataaagataa actgataatc ggaaaatttt gttccatagc atgcggagca aaatttattt
    12241 tcaatagcgc aaatcatacg ttatcttcct tgtcaaccta cccatttcct atcttttttg
    12301 aagaatgggg attagatgta aggaatatta cgaaagcatg ggataacaag gggaatattg
    12361 ttattgggaa tgatgtttgg attggttatg aagcggtcat tttatcaggc gttacgattg
    12421 gtgacggtgc aattattgga acgcgtgcag ttgttacgaa agatgttcca ccttatacaa
    12481 tcgttggcgg tgtacctgca cagacgataa gaaagcgctt ttcacaagat acgattgaca
    12541 ctttgttaaa aataaaatgg tgggattggt ctaaggagcg tattacgcaa catatatccg
    12601 agatacagtc gggaaatatt gaacatctga tatgaattgc cggacgacgg caaaagaaaa
    12661 aagccgtcgt acagcagata ttttcatgcg tctatgaagc ggtggctttg attttcagag
    12721 ccgccgcttc tttgcgttta ctcattatat tctgaaaaac tacggcggta ttgaggaagt
    12781 gctgtcgtac ccgttttttt gcttacatgg tgctcttaat ttatcaaaaa actgtatctc
    12841 gcaacagact aagtatgcct agcaaatcat ttagtgtgtg tttgtatcga ataatcttca
    12901 aatacccatg agtttttcta ttgtataggt atttgttgca ataatcctta ctgggaagaa
    12961 agggggtgaa acaatgaacg attcagagca atacaaagag catatcgagt acacttttgc
    13021 agccttttgt aaagttgttc tccgcaatgc ttccctgtct gcttatcggg atattgccag
    13081 gcgtcagaaa cgggaaatat cccttgatta tctcatggag ggaaggtatt acaatccgtc
    13141 tacaacagac agctattttg cgaagcaaac aagttcgatg gaattgattg tgtgcggcga
    13201 gagaatcgta atagaaaatg aacgattggc aaaagtattt tccggtttac ccaagctgcg
    13261 gcaggaagtt ttggtactgt attttttctt tggatatacg gataagaaaa tcggagaaat
    13321 gtatgggaaa agccgcacga cagtaaacta ctggaaaatt gcagcactta aatatctaag
    13381 aaaagaaatg gagtgtaaat tacggttgaa tggggatgtc ggttaatacc gatttttaaa
    13441 ctctaaatcc taaaataaga atctcccata aaaatcagtg tttttcatac ttgatattct
    13501 gtgggagatt cttattgttc tttttctgta tatattttag ggcgcaaaac acccataact
    13561 gcatttttga acatgcacat tttttaagcc gtcttttcct cggtttttcc ttcgaatttt
    13621 ttaatctcat catgaagaaa acgatgatat ttattcatgt tccgaccaat ggcatacagc
    13681 atgaattctt tatacacctt ctctgacgtt cggtagttga atcttcggaa actatcattt
    13741 cccttgatat ctccaaaatg tccttctgtc tggatggaac ggatctgacg atttagaatc
    13801 cctttctcac tttggatgtt tgcatgggat tcctctttca atgtttcccc ttgttcattg
    13861 atcttcataa ctttgttttt ctcagcatct ttttctgcgt tatatttata taagcatttc
    13921 gctttgtgtt cacaaccact acagtctgca catccgtata cctcaaaagt ctgggtataa
    13981 cccggctgtt ttttggtctc tgtgcggata tgatgcaatt ctcttccgtc atgacaaaca
    14041 taataccgtt catcctcaaa tatctgtgtt ttcatgttgt aatattttcc aatatcttct
    14101 ctgtaagcgc gtgttttccg tttttcatga tcctgcagct tgatgtaact ggatatctta
    14161 tttttcttta aatacagaag atttttctcg ctacaataac cgctatctgc ggttacttct
    14221 tccaaaatct ccccaaatgc atttttatgc ttttctaaaa ccggaatcag tgtgttatag
    14281 tctgtccggt cattgcttac ataagcatgg acaatgaaat aattctctac tgcgatctga
    14341 acattatatg cggcttttaa ctgtccgttc agcatgtgat cttctttcat tctcataaag
    14401 gtggcttcta aatctgtttt ggaatagctg ttcctgtcct ttcccatgat ctcaaaacat
    14461 tctttgtatc ccataaggcg ttcgccgcag gtttctaatt cctcataaag ctgctggagc
    14521 tccgatttcc tcttcccttt tccgtaaaca aacgcaatct gttccttctc tgcgatctga
    14581 gtcagatttt tctgaagttt caaaatctcc aatggggaac agttgtcaat ctcgatgatc
    14641 gtattattgg acaacttttt atgttttgtc agtttccgct tccggttctt ttcaatgaca
    14701 tctcttacct tatccattcc ttcgatcaca aacatatgtg catggggaat gtcatatttt
    14761 atgccatact cattttcatc tatccatgca ttatacttct gatacagtga atcaatcata
    14821 tcgagtaagc ctgcgagatg ataattgatc gtccctctcc acacaaatgt atagcggttt
    14881 gcattggcct ctatttttgt tccatcaata aaaagggatt tcaatgtgat cagtccttct
    14941 ttttgcaggc ggcggagaaa ctggtaattc aactcatcca atacatctgc agtcagtctt
    15001 ttattcttga actcataaaa agcatccctt tttggtttct gacctttggt aagccagata
    15061 aatgcaaggt ctctttcgca taattccaca atacggtcaa cagctctaat cccacgcatg
    15121 tttgcgtaag taactacggc atacatcata attgggttat acccggttct tcccttatct
    15181 gaacaattgg ctgcaaattc cggtcgaacg gtacgctaat tccaatatta tcggtatgtg
    15241 cattctgata taacggtatg aactttctgc tcgaacggta cgcctttcct ttattattgt
    15301 gatgtaacta ttattcatca cagtgtaaag gaggagcaat tatgcacgac tacactacta
    15361 tcataggtgt catagaacta agacttaaca agatcagcta tgacaatgtt cagaaacgat
    15421 atcgaattgg aagaagcgga atctcactga ttatggaacg ctatcgggat tctggattat
    15481 cattggatga tttaaagcag atgccggccg aaaaggtggt caatctgatt tatcccaagg
    15541 ataatcttcg ccacaaaaac attccgttgc ctgattttca ccaaattcat gagaacatga
    15601 tccaaatggg aaagaatgca gaccttggat ttctgtggat cgagtacaaa aagaaaaatc
    15661 ctaatggtta tcagctatca cagttttaca aactgtatag agactttctg gtaaatactt
    15721 atggatccac aaaagtatcc atgccggttg aacgaattcc cggtgaaaag atgtacatcg
    15781 actgggtagg tgatcaacca gagctgcttc tggatccttc aactggagaa ctcaagaaag
    15841 tacacatttt tgcaacaact cttggtttca gcagtcttgt ttatgcagaa gcctttccag
    15901 atgaaaaact gccacatttt atcactggta ccgtacatgc attatctttt tacggtgctg
    15961 ttcccagata tcttgtgccg gataatctga aaacggctgt tacccgacat aataaggatg
    16021 agcttgtatt acagacggct ttttcagatc tggaaacttt ttatgataca atcatacttc
    16081 caccaccgcc gcgcaaacca aagggaaaag caacgattga aaatcatgtt cgctttctgg
    16141 aaatctattt agtcgaagaa cttaagaaaa atacctatac ctcgcttgag gctttaaatg
    16201 atgctacaaa aagaattgta gaggacatca atcagcgacc atttcagaaa aaatcagata
    16261 tccgtaaatc aaggataact ggatttgaaa agtatgacaa accgcgtatg aacaagcttc
    16321 ccggcgagaa ttacacgctt tgtgattata agtactttct taaagttcct gataattatc
    16381 atcttgaata tgatgcccac tactactctg tattgtatac ccaaagagga aagccggcaa
    16441 ttctaaaggc aacaatggca gaaataagga tctgcgatga gtacaaccgt ctgatctgcc
    16501 gacatccgag atcctacagg gattttccgc tatatatcac agatgacagc catatgccgc
    16561 aagaacatct ttattataaa gaggttaatg cccatgatgg tgcttattat cggcggtggg
    16621 catctgtata cggcgattct atggtcactc ttatagatag gatcctgcgc agtccaaaac
    16681 atgaagaaca agcttacaac agttgtgccg gagtccttca ttcctgtaag gatgtgccac
    16741 acaggctcgt acaagaagct gcggataaat gtgtagaagc aaatgcctgc aagtattctt
    16801 attttaaaaa agtacttggc atggtccaaa acaatcattc tattaataac acagctgcat
    16861 caggaacact tccttcccat gcaaatatcc gtggaaagga ggcctataaa taagtgagaa
    16921 tacaaagcga aatcacattg acaccggaag aacaggccct gatttctcga ctgaaaagtt
    16981 tcagagttcc ggaaatggca cgtatattgg aggaacagtt gagagatccg aatgcggatc
    17041 tgaatacttt taaggaacgt atgtcagcga tgatcaattc ggaatggcaa tcaagggcgg
    17101 ataaacgctt caatcgtttg atgaaagaag ctcatctcag gtatccggct gcagatcttg
    17161 atgagacgat ttatcgtcct gagcgtcagt tagacacgca gataattgaa cgtctgagca
    17221 cttgtcactg gatagaggaa ggaaaaaacc tgattgtaac aggttcttca gcaagtggta
    17281 aaacgtattt gatcaatgct ttttgcgtaa cagctatgaa acagtccaaa agtgtcaggt
    17341 atatcaaagc gaacactctt atgagtgaaa tggaacaagc acgtatcaaa gctactaatc
    17401 tggattatct gaacaaactt acgaaactcg atcttcttgt gatagatgac tttggcctga
    17461 tggatcttga tctcgataaa tgccgagatc tttttgaagt acttgatacc cgtgatggac
    17521 ggaaatctac agttgtgatt tctcaatttc ctgtcagctc ctggtttgat atgtttgcag
    17581 ataacactta cgcagatgcc tgccttacaa gaattaccga caagcatcat acatatcgtc
    17641 tggaaatgaa tggtatcaac atgagagaaa cggaataaaa gatatcaata gtattttgta
    17701 ccgctaaaaa tggaatagcc gttccgcgca tgcggaacgg aaatcccatt caaccgtaat
    17761 ttacacaatt ggccaacaag ccagaaaaat ctaattcctc catcactttt ttcagggtat
    17821 agactggatt gtcgtcaggt aaacacaatt cgaagaaact gaagttaatt ttctgttgcc
    17881 ctaattcaaa aaattcgtta taatacttat tgtttagcat agttacatta taacatgtaa
    17941 cggagaagag atggttgtcg ttagccatct ttttctcttt tatggaaaaa tttcaggggc
    18001 agatgtgacc tggtatgagt cacatctgcc cctatttgga actatctatt tcccgatagc
    18061 cccttgatag cgttagtaaa ttaaaataaa gtgtcttata tatagtatat agggacttta
    18121 taatagaaat cttacaaata tgaataaatc catgtcctaa aaatatacat ttcatggaaa
    18181 atataatgca aaaaaatatt aatatgatac aatcaagata agcgagaagc aaggaattct
    18241 atgacggcaa gaatttcatc ttgcttttgc gttgggaatt ttttgatatt aatttcaatt
    18301 ttttgagaaa tagaatcaac ttcttctgtt tgataattaa ttaaaagatc gcagaaaatt
    18361 tcttgacgag ccacatgaag cgcatctgca atttcacagg caaaatctac tgtgagagaa
    18421 gaagaaccat tttcaatacg acttataaaa ctaggagaaa catgaagttt ttcggcaagt
    18481 tgattttgag taataccttg agccttgcga atttcctgga tacgttgtcc tgttttcata
    18541 atggcattca tctcctttct ttgctatata ttgtaacaat aatagtaata gaaatgaatt
    18601 tacatatatg caaactattt acaaatagta aatacgactg tactattaag gaaaaggagg
    18661 tacggttgaa tgttttataa taaggttgaa gtaaaagcca ttattcttgc agtttataat
    18721 attgaatcat tgggattaaa tagtagtaga attttgttga agagtattgt ttggttgtgt
    18781 aaacaatatg agactacgaa agagaattta tatctagaga aagcaatgtg gcatatatat
    18841 gcatatttag aattaggtta ttcatatgaa actggagaaa gagaatttaa tatagtattg
    18901 gagtatttac aactgaacag agcggatatt tttcctaaaa gagagtggga atataaaaag
    18961 atcactttaa ccaaggctaa tgtgaatcgc ttattaggga aatggaaccc atattttcaa
    19021 tcaatgaaaa ttaatgatgc agttgcagat attataaaga aagttcagga taaagaatat
    19081 gggaaatata tttatcattg tgggaaagca atagaagaat gtgaagaaaa tacgttatgg
    19141 gaaaaaactt ttattctgta tgtaacaaaa gatgaggcaa ttcttcaaga tatgaataag
    19201 agtaaatatt atatgcttaa ggagatacaa catgattaga attgcaacta tcggaggtag
    19261 tatattgggc gtgaatcgat gtgttttttt ctctagttaa atatttcttt ttgttaatgt
    19321 aatgattgtt ctgtgtgtga gaatggggag atgagaaaat attaattgca ggagtaactc
    19381 ttttattttt tttagttaat gcaacaacag atatgattgc tgcaagtgca tgttttgttg
    19441 ataaaaggct ttttaatttg caattcgagg tcatattctt ataatttaag ggcaaaagaa
    19501 agataagatg ttataaatat gttatattat aaatatcgga aagaaattaa aaaaaatgtg
    19561 cgtaatctta ttggaagagg gactcctggt ttttcagtgt atgaaaatta atgatcttat
    19621 tggtaaaata ggaaatcatg aagagagagt acctatccat taagttgtgt ataaccagaa
    19681 tgagtataca ttttatgatg ttgtaaaaat aaatactata tttttgagga aaaaagtgaa
    19741 aatgattaaa atagttataa tagatgatga agaaaatata ttaaatattg ttgaaaatat
    19801 tgtgaaaaaa gcaatggaaa ataaaataga aatatataca tatctaagtg tgaaaaaatt
    19861 ttggactgat tttgaagaga aaatggattt tgacatagtg atttcagatg ttgagatgcc
    19921 ggaaattggt ggaattgaat tagggaaaag gataaagggg aaaaagtcag atatatattt
    19981 gatatattta acatcttact ctatgtatgc agttcagagt tatgaaatag aagcatatca
    20041 gtatatatta aaagaaaata tgcagtatag acttccaata gtgctcagtt cactgattaa
    20101 taaatttgaa aaagataaag ataaatttag gtttatagga agtcctatga ataaagaaaa
    20161 aatatattat aaagaaatta tatatatgtg taaagaaaaa acatctaagt atgtacgttt
    20221 cgtgacaaca agaggaatat ataaagaacg gataacatta acacagatta taaaagaatt
    20281 aggaagtgca gaattccttt taacagaacg aggttatgta gtcaatgtta atcacttgga
    20341 tggaataaag gaaaatttga ttactatgga taatggagaa caaattatta taagtagatc
    20401 taatttgaaa agagtgaaag agcaaattaa tttatataga ggaagattgt agaagtgtat
    20461 tatgatgaag atgatacaaa tgtggattgc attttttgaa atatggttat gctaccaatt
    20521 tttgtatgct acaattttag aaccaaaact tttaactaaa aaaaatagat tattcgtaaa
    20581 tttgaatatt ataattgtag gactcttatt aagtataaat agggaaattc tgtttttttc
    20641 ctatagtatg atgatatttt gtgcattggt aatatgtatt aatctatttt ttatagttaa
    20701 aaaaaatcct tttttaatta cgaatctcgt gtttctctat tttttaggta catctttgtt
    20761 ggacttattg tttagttttt gggggatgat atttttacaa acagaatttg aagaggcagt
    20821 ttattggtat gcaaactctt attggaaaat tggaatttta ttgtgtacaa gaagtataac
    20881 aggaataata gttttttctc ttggaaaaag tagagataga gaaatagata tcagagaatt
    20941 tcaaaatatt attttatcag cgaatcttgt gttatttgtg gttatgagag gatatcaatt
    21001 tgttttggta aacatgtcaa atggtatatt acaaatgcga ggagatatta ctagtttttc
    21061 tcttttaatc atcattgtta ttgtaatatt tgttagtagg gcttttgtga aaagcaagat
    21121 gttacaaaag caaaatgaaa tgctaaagat gagagaaaaa ttaaaagaac aaagttatca
    21181 agagttgcta tgtgttttag aacaaaatcg ccaattaata catgatataa aaaatcatat
    21241 gattatactt caaagtcaag agagaaccta tgattacgaa gggattgcta actatgcaaa
    21301 agaacttgaa aaagtttttt tgagaacaac agaagaaata tggacaggaa ataaagtggt
    21361 tgatttaata ttgagacaaa aaaaatattt ggcagaagaa cgcaacatag agttttttat
    21421 tgaaacgatt tttttacccc aatggccctt caaggatagt gaattatgtt cattgtttgg
    21481 aaatttatta gataattcga tagaggcatg tgaaaaaata aaaaaaggaa agcgatggat
    21541 taaagtacaa gtagagaaac agaacaggtt attattttta gatatatcca attccataga
    21601 agaaaaaata ttagtgcgag gaggtaaatt aataactaat aaaaaggata aagcaaatca
    21661 tggatatggg ttaaaaggga tcgaaagaat tgtaaataag tatgaaggag aaatgtctta
    21721 tcaagtaaag ggaaatctgt ttaaaattat tattacattt tttctaaaat aatttttata
    21781 gtatgaaagg aggttaggat acaatgcaag aaaagcaaga acattatttg gcaggagatt
    21841 tggaagtgga gttagaggaa tttaaaagtc ttgcacaaaa tgaggagtat gcagaagggt
    21901 ttttatccac aacgatcaaa tgtggaacat ttttaactat ttattgttgc taaaggaaaa
    21961 ggtagagtgt tttacactct gccttttatg atgatgttaa atgattacgg aggataatat
    22021 ggagaagtat agtacttatt tatcagaacg taaatattta tctctaaacg aatatgagat
    22081 tgatatttat aaagaaatat attggaaaaa gatgttaggg gatacaatat atgaaaaagt
    22141 tttaacttat caaaaaaata taaacgatta tttgagcgga agaacgtttg atattgaaac
    22201 attagaagtg aaatgtgaag agaaattact cgattatttg aaaaaagaag atgataacag
    22261 agagggtgaa tttagacata agatatattt taaggaattt ttttcccgag ttacaaatta
    22321 tggacttact aaacttaaaa aaagtgtaaa aagggaagtt tttactgcaa agaatttaca
    22381 agattttagg gaacaattag ccatacagtt acaaactgtt tgtataagaa cattaattac
    22441 acgtttgcat gtaaattacg gttgaatggg atttccgttc cgcatgcgcg gaacggctat
    22501 tccattttta gcggtacaaa atactattga tatcttttat tccgtttctc tcatgttgat
    22561 accattcatt tccagacgat atgtatgatg cttgtcggta attcttgtaa ggcaggcatc
    22621 tgcgtaagtg ttatctgcaa acatatcaaa ccaggagctg acaggaaatt gagaaatcac
    22681 aactgtagat ttccgtccat cacgggtatc aagtacttca aaaagatctc ggcatttatc
    22741 gagatcaaga tccatcaggc tgttttttgc aagcactttt tggagaaaaa tgcaaaatat
    22801 ttttggagaa tgttgcatct ccaaattgga gaaagttgca aggcctcggc tggcagctat
    22861 tctgccagct acatagccat tgcagaccat atttagttgt tatagcgtga gatatggaaa
    22921 cggaagttcc gagttttcat cttcatgtgc atgttccctg aaatagcgga actcctcatc
    22981 cagctcttta taatggataa aatcatttag atatctcaga tcttcttctg cgcatcggtg
    23041 atcttctatg agatcaagaa gataatcatt catctcctca tagcgttcct gaagattttg
    23101 atattttttc tgttctttga taactttttt atttttagcc attgttacct gcctcctgac
    23161 tgctgattct tgaaagagtt gcattgatgc ttgattcacg taaccgatta ttgatccccg
    23221 ggaacagaat cagttccaca tggtgggtga gcctgccaat cagtgctgtt gtcatccgtt
    23281 ggtcataaag aacgttcacc cactgtgaga attcaagatt cgtgtttaaa atcaccgatt
    23341 tctgctcgtg tatctcagaa agataatcaa acagaagctg tgaaccggtg cggtcatacg
    23401 gaacatatcc gaattcatcc agaatcagta tccgggcact gttaagcttc tttttcagtg
    23461 cagtaagctt tccgctgctc tgactctcgg aaaagagatt gataagtccg gcagtgcggt
    23521 agaatcttac cggaatttcc tgattacatg cagacattcc aatcagaatg gaaagcattg
    23581 ttttaccggt tcctgttcct ccatacatga tgacattttt tcctgtatga taaaactcca
    23641 ggtctaacag gctttggaag ctgacgtctt ccgggaaatc tatctcatct gccctgaatt
    23701 cctccacgcg gtatctacgt gggaagccgg cggtattgag gaacttgctc ttcctttttg
    23761 ctgtacggta ttcaatttcg tttgtcagga ggtttaaaag gtattcctgc ggtgtgtctc
    23821 ctttctgctc gaaagcctgc cctgcaaagt tcgtggacag cttgagctgt ttgcagcatg
    23881 ctgcaatgga tttttctata tcagccattt gagacacctc ccttcttaag ggcggcatcc
    23941 agcattttca gatcatttct gaacggaatg accttctgct gtggcagtaa aactttgttt
    24001 tcaagcggag gcagaagcgg tacatctgca taggttcgcc tgtaaaggct ctgcagactg
    24061 tccggatctg tggcattcag ccggactgct tcgtcaactg ttctgacagc actagcaaac
    24121 ccggttcttt ccgtaagttc tgcaagcacc ttcaggacac gtccgcgttc cttgctttcg
    24181 cagttatcca tgtatatctg catggtttgt ggcatcatgt catatatgcc gctgtttcga
    24241 agagaacggg gtttcctggc gatatatgta aggtatggca gccagtccat tctttcatgt
    24301 tcattgccgt aaaggcgctt atgacgcacc acttcgtgca tatctttgtc catgacaatc
    24361 acatcagagg atgtaatctt gagatttaca atggactcac agaaagccgg tgaagcagaa
    24421 taacggtgct ttcctgcgtc aagagtaaac tttccatatt tatccgttgt tgccgttgtg
    24481 taaagtgccg tatcaaacgg aacggaagga agcggcagta aacgagcctt atcttcttca
    24541 aacagtttac tgataaagcg gtcatcatcg tcatcatagt gctcacgctg catatcgatt
    24601 tcacaacgat ccagaagatg cttgttttct ttcacaagat catcaaagcg gggtaccggt
    24661 acaagttcgt tgcggcgcag gtagccaacc ttgttttcca cgtttccttt ttcccatccg
    24721 gattcaggat tcataaaaac cggcttaatg cggtagtgtt cacaaaagcg ttgaaaccgc
    24781 tctgttacat tacgcccgcc acctttgatg atttcggtaa caatggttct ggtattgtca
    24841 aaccagattt ccgtgggaac accaccgatg tgctcaaata tggcaaccag tccttccaga
    24901 agacattcca tgttttcgcc ataattaagc tggaggaaac ctccgttact gtagggaaaa
    24961 ctgagcacaa ggtacttagc ctcgtgatga agcctgtcat tttcataaaa atcggctgtt
    25021 ccaaagtctg actgggcttc gccgggatga tgattaagag ggatatagcc atcggttctt
    25081 tttagccgta gttcctcttt cttctgtttg acgtataagg caacaagccg ataactgcag
    25141 ccgaaaccat ctgcttcatc cttgaggcgt ttaaatactc ttttggctgt atgccgttgc
    25201 tttcttggtg caagcttgtc tgcctgcagc cattcatcaa tcaaaggttt gaatgggtca
    25261 agcttggatt cgtgaacctc tgatgatgca ggtttgggag atggattgtt aaagtcctcc
    25321 atatccacat attttttgac cgttttccag ttaaggccgg tctcagatgc gatttcagaa
    25381 atgttcttat cttgccggta gaacatatct ctgatatgat gtatctgatc cattgtagtt
    25441 gacattctcc tttcctcctt gtctttattg tttggactac aataaagata aggttaatgg
    25501 tttttggata tacctgcaat ggatcttttc atgggaatgc tcatacttgg tggctgccac
    25561 tcaagcgcta caccgttcct gagcgcttct agcgaatgcc ttgcaacttt ctccaatttg
    25621 gagatgcaac attctccaat tcccgtttgc aactttcggt aattctattt tacaataaac
    25681 acatcaggcc aaagtcatct atcacaagaa gatcgagttt cgtaagtttg ttcagataat
    25741 ccagattagt agctttgata cgtgcttgtt ccatttcact cataagagtg ttcgctttga
    25801 tatacctgac acttttggac tgtttcatag ctgttacgca aaaagcattg atcaaatacg
    25861 ttttaccact tgctgaagaa cctgttacaa tcaggttttt tccttcctct atccagtgac
    25921 aagtgctcag acgttcaatt atctgcgtgt ctaactgacg ctcaggacga taaatcgtct
    25981 catcaagatc tgcagccgga tacctgagat gagcttcttt catcaaacga ttgaagcgtt
    26041 tatccgccct tgattgccat tccgaattga tcatcgctga catacgttcc ttaaaagtat
    26101 tcagatccgc attcggatct ctcaactgtt cctccaatat acgtgccatt tccggaactc
    26161 tgaaactttt cagtcgagaa atcagggcct gttcttccgg tgtcaatgtg atttcgcttt
    26221 gtattctcac ttatttatag gcctcctttc cacggatatt tgcatgggaa ggaagtgttc
    26281 ctgatgcagc tgtgttatta atagaatgat tgttttggac catgccaagt acttttttaa
    26341 aataagaata cttgcaggca tttgcttcta cacatttatc cgcagcttct tgtacgagcc
    26401 tgtgtggcac atccttacag gaatgaagga ctccggcaca actgttgtaa gcttgttctt
    26461 catgttttgg actgcgcagg atcctatcta taagagtgac catagaatcg ccgtatacag
    26521 atgcccaccg ccgataataa gcaccatcat gggcattaac ctctttataa taaagatgtt
    26581 cttgcggcat atggctgtca tctgtgatat atagcggaaa atccctgtag gatctcggat
    26641 gtcggcagat cagacggttg tactcatcgc agatccttat ttctgccatt gttgccttta
    26701 gaattgccgg ctttcctctt tgggtataca atacagagta gtagtgggca tcatattcaa
    26761 gatgataatt atcaggaact ttaagaaagt acttataatc acaaagcgtg taattctcgc
    26821 cgggaagctt gttcatacgc ggtttgtcat acttttcaaa tccagttatc cttgatttac
    26881 ggatatctga ttttttctga aatggtcgct gattgatgtc ctctacaatt ctttttgtag
    26941 catcatttaa agcctcaagc gaggtatagg tatttttctt aagttcttcg actaaataga
    27001 tttccagaaa gcgaacatga ttttcaatcg ttgcttttcc ctttggtttg cgcggcggtg
    27061 gtggaagtat gattgtatca taaaaagttt ccagatctga aaaagccgtc tgtaatacaa
    27121 gctcatcctt attatgtcgg gtaacagccg ttttcagatt atccggcaca agatatctgg
    27181 gaacagcacc gtaaaaagat aatgcatgta cggtaccagt gataaaatgt ggcagttttt
    27241 catctggaaa ggcttctgca taaacaagac tgctgaaacc aagagttgtt gcaaaaatgt
    27301 gtactttctt gagttctcca gttgaaggat ccagaagcag ctctggttga tcacctaccc
    27361 agtcgatgta catcttttca ccgggaattc gttcaaccgg catggatact tttgtggatc
    27421 cataagtatt taccagaaag tctctataca gtttgtaaaa ctgtgatagc tgataaccat
    27481 taggattttt ctttttgtac tcgatccaca gaaatccaag gtctgcattc tttcccattt
    27541 ggatcatgtt ctcatgaatt tggtgaaaat caggcaacgg aatgtttttg tggcgaagat
    27601 tatccttggg ataaatcaga ttgaccacct tttcggccgg catctgcttt aaatcatcca
    27661 atgataatcc agaatcccga tagcgttcca taatcagtga gattccgctt cttccaattc
    27721 gatatcgttt ctgaacattg tcatagctga tcttgttaag tcttagttct atgacaccta
    27781 tgatagtagt gtagtcgtgc ataattgctc ctcctttaca ctgtgatgaa taatagttac
    27841 atcacaataa taaaggaaag gcgtaccgtt cgagcagaaa gttcataccg ttatatcaga
    27901 atgcacatac cgataatatt ggaattagcg taccgttcga ccggaatttg catttgcacg
    27961 tctataagga aaaagaaaaa ttaagaggtg aaacaccgat aaaggaatat aattattttt
    28021 gcgaaaaata tgtttctaca tttgaatttg ttcatgaatt gtttgaaata tatcccgtat
    28081 tatatagaat tatagaagaa aaaatagaaa attttataaa atattatata gagatttttg
    28141 atttttttga aaaagataag aacaaaatcg gagaaaaaat atgtggcgga aaattggtga
    28201 aaaggataga agaaatagat ttttctcttt ctgattctca taagagcgga aagagggtgg
    28261 cgaaacttaa attggataat ggaatgtgga tattatataa accaagagct atgaaaaatg
    28321 atgaaatata tatgcaatta attcaatgga taagccatca tattggaatg aaacagtatg
    28381 aatatccttt tttaacatat gaggaacata gttggacata tattgttgag cagagttcct
    28441 gcaattcaga aaaagagtta gaaaactatt acgtgagatt cggaatacat ctttttttaa
    28501 catatttgtt gggggcgcaa gatttacatt atgagaatat aattgcagca ggtgaatatc
    28561 cggtaattat tgatttggaa gctttatctg gaattccaag aaaacaaaag ggaagatcca
    28621 tagatgaaat aatatatcat caattagtag aatcggtatg gaatacggga ttactcccat
    28681 tttgttgggg gacacaaaga agaaaagggg tagagtgtag tgggataaat ggtaaaggtg
    28741 gacagaaata tttatttaag attccggttg ttgtagaagg tgggacatca aatatgcata
    28801 tagaatatat gtgccctatt tccgaagaaa agcaaaattt acccaaaata aaagagggat
    28861 ttatagatat atcacattat aaagcgaaaa taaaagaagg attttgtaaa gcgtatcata
    28921 ttgcgttaca gagaaaacaa gaattatatt gttgggtgac aaaactaaaa aattgtgaat
    28981 gtcgttgttt tatggaagat acacaacgct atgggatgct tttgtttagt tcctatcatc
    29041 cccaattatt aaaagatggg gcagaaagag aaattttcct tcaggctatg tgggataata
    29101 gaaataaaaa tgattaccta atcgttgata gtgaagtgaa ggaattactg agaggggata
    29161 ttccattttt ttcatttcat atggattcta aaaatctgct attggggaat ggtggagtga
    29221 tttctaatta ttttatgaat acaccaatgg aattattata tcaaaaagta cggttgttga
    29281 atataaagga tatggaaaaa caatgtgaat atatagacat ttcttttgac atactacaag
    29341 caccaaaaca acagtgtgta aataaagtgt ataagacttg tgagaaaaag gttgattgta
    29401 gtgttgtaga acggaataat acagcaaata gcaaacttgt ggatatgtat attgagagat
    29461 tattaaaata taaggttttt aattatgata atacagaaat tagttggtat acaattcaac
    29521 ttgaagatca atatggatgg agtgttaaaa caatgaatat atatttatac gatggtttag
    29581 caggtatgtt cttaataagt tgttttttgc aaaaatatca aaatactcgt gaaattgcca
    29641 agataaataa aatattacaa tccacattat ttcattatac agaaaagggc tatgagtcga
    29701 tgaaaaatct tcaatcccaa aatgtcggtg catatgaagg ggaaagttct atattattaa
    29761 catatcttat tgcatatcaa tacaaaaagg aaaagatata tttagattat gctaaaaaac
    29821 atataaaaat aattgagcag ttgatacaga tggatacaaa ttatgatgtt cttaagggga
    29881 atgccggcgc tgttttggtg cttttaaaac tatatggtat atgccctgaa aaaaaatatt
    29941 tagtattagc agaaaaagca gtagataggt tacaggaaag agcattaaat ttagagcatg
    30001 gagtaggttg ggaaatcgaa aaacaagtgc cgatggcagg aatggcacat gggaatagtg
    30061 gaattttgat ggcctttgta gggatgtgga agaaaacaaa taaaagtaaa tattttgaat
    30121 ttgcaaaaaa atattagatt atgaagattt tttatatgat ccttcgatgg gaaactggaa
    30181 agatatgcga acacatgagt gcatacagga taacgtggga gctatagcat ggtgtcatgg
    30241 agtgtcgggg atactgtggt caagaatgta ttgctatgct caaaatacag ataccatttg
    30301 gagagaacgt attaaaacag acatgtttcg agcatatcag aaattggtga aatattggag
    30361 aagagatagt tggtctttat gccatggaaa ttgcgggaat ttgttggttt tagaaaaggc
    30421 aaaaacattt tttgaagaat gttcaattaa tgaaaaatat atttttatga aagaagatat
    30481 tacattgtta ccacaagaaa aaatgaatcc aggtttattt aatggttatg gaggtattat
    30541 atattatatg ttgaaaatgc aggacaagaa tataccagat attttcttat aaataaccaa
    30601 taatggtcaa tatatatact tgagggtcaa agtcttgaaa taaatacctt aaatagttag
    30661 agtataatta taatcgatta taaaaaaaat atggaaggag gagctaatat gaaaacacca
    30721 aaaattgtag ctagaggatg gacttgtgtg ggatgtgcgg gttgtacagc gtgttgggca
    30781 agcgcaactg caataagtca tgtatcagca gctaatatat ttggatagat taaacgcgac
    30841 aatgttaaat aaagatttac attgtcgcgt atttaaaaat aattgtatta tttagggaga
    30901 aaaataatga aagaatattt gttttgggac gatgaaattt taattgaatc aataaatgct
    30961 gatattattt gtttatacgt tttcaaaggg aaagaagtag aaaaaagaat gattaataat
    31021 atagcaaaag aaattattct tagaattaat ggcatgcata catttgatga tatagtaaag
    31081 tatttttcgc aaaaatacga gacaagtata gaagaagttg aagggaaatt agttcctttt
    31141 cttgaagaat tagaagaaga gtatggactg agtattcgga ctagttcaca tcctaaagag
    31201 aaaaaggtca aagaaaaaca acagaatttg tatccgcatg tagcatcgtt agaaattact
    31261 cataaatgta atcttaagtg tttacattgt tatgggagtt ttgattgttt aaatcagaaa
    31321 agtatgccaa tagaacggat aaagaaatta cttaaggatt taaacgatat tggaacatgg
    31381 gttattgaac ttacgggagg agagtgcttg attcatcctc aatttaaaga aattttgcta
    31441 tatgcccttt cgttagactt tgttcatatt aacatattga caaatggcgt tgcattaacc
    31501 aaagagataa aagatattat tatatgtaat aaagataggg tgtttgtaca aattgatata
    31561 catagtttgg aggatgaata tttagagtgg tttacaggtg caaaaaatat agcagaaata
    31621 gttaaaagca atgtgagaga gctcgcaggc gaaaatgtta aaatgagaat tgcaacaact
    31681 gtaactaaaa gaaatataga tgaagtggaa aaaatagcag attgggtata ttctctcgga
    31741 ataaaaatgt atgtcccatc ttcggttata gaattaggaa gggctgtgta ctctgaacca
    31801 gatatattat tagatcaaga aatgcagata aagttgttta aaacaataga taggattaat
    31861 gaaaaatacg atggatttat aaatactcta aacagtgatg aatttagaca gagttccaat
    31921 tgtggttgtt tatcttcaca cgttactatt gctgcgacag gagatataaa aatatgcaca
    31981 atggataccg gagaatatac aggttatcaa tggggaaatg tttttgaaca gaatataaaa
    32041 aatatatatg atgaaaaaca aagtgaattc ataatatttt cggaattaga agcaccaaac
    32101 gcattgtcag aggagtgtcg tgagtgtgaa aaaaggtttt tttgctcatc atgcatatta
    32161 agaggaattg tggcagggaa agagaagggt gaaaaatgta aatggataaa aaatatgcca
    32221 tttgtgtaaa aattaaaaga agtaaacaga tagcatagag gaagaatgga tatgttaagt
    32281 gtaaaaaatt taaaaaagga atacgataaa ttcaaaattg ataaagttag tttttcggtt
    32341 gaacgtggga aaattacagg gcttattgga aataatgggg cggggaaaac aaccgtattg
    32401 aaatgtgtga taggagttct acaatatgat ttcggggaaa taattattga cgggttaatg
    32461 cttgaacatc atgaggaaga gtacaaagaa aaaataggaa tagtatttga tagtggatat
    32521 ttttatgaaa atttaacgtt ggaagaaatg aaaaaaatta tttcagcagc ctatcagaac
    32581 tgggatgaag aagtatatca aggatattta aagaaatata agctggattc aaaacaaaaa
    32641 atagaaacgc tttctcaagg aatgaaaatg aaatacgctt tagcacttgc gctatctcat
    32701 aatgcagaaa ttttaatatt tgacgaacca acgagtggtt tagatccaaa aacaagacaa
    32761 ttattttgcg aagaaatgat agatcaaaaa aaacatggaa gaactatttt gttttctacg
    32821 catattacat cagatctgga taaaatagga gataatatta ttcttatgga tagagggaga
    32881 attttaaagg aagctacaaa acaagagttc cttatggggg aaccaactgt agaagccgcg
    32941 atggtgaact taataactga aggaggaaaa gcatgaaaat attaactttg atagagaagg
    33001 agataaaact agcagggaat tatttttggc tatccataat ggtgttaatt ggtattccta
    33061 tttttttgaa tcagcagagt ggtggacaat atagtggaat ttatacatta atgattgctc
    33121 taaatttttc aatatatttt ctttttaata atattttttt aaacgaggat aaatataaag
    33181 ggaatttata tatgctagca ttgccctttg gtaagaacag acttgtattg gcgaaatata
    33241 tattagcgat tctgatgttc atatttgcta taatatgtta taaggggatg gcaagtgtag
    33301 gagtatattt aaatattgta ttttctcaat taaactattc ggagatgtca attgtatttt
    33361 ttgtgtttag tctaataata ggtatattct tcccaattta ttacaagttt tcttatgcaa
    33421 aaataaaagt tcttttggcg gcaatcatga tttttttacc gacatgggga ttagtgatac
    33481 tcaaatatat tctggatatt gaagtggtat atcaaaaaat tgtgataagt acgcgtgctt
    33541 tgattagtat taatatttta agcattatag ttatgttatg ttctgtgtct atttccataa
    33601 aatgtttgaa ttctaaaaat taaaatcgtt atatgattgt gtaggataga ataaatgaaa
    33661 aaaagtaata taaaaaaaag aatatatcaa atagtaggaa taacaatata catatgtata
    33721 attcttttag tgggtaaaat gacaagaagt tttttgcagg aattcaaata tgagatgggg
    33781 gagtttaata ttgctacatt agggagtttt ataggggctt atgttgtatg cgtattggta
    33841 catgaattag cacatttaat cagtttttta ttgatgggat ttccagttgt agcagcggaa
    33901 atatgtggta tacttttgct tttttcacat agaaaaatca aagtgaaaat taattttagt
    33961 agaattatgt taggtggttg gatattgcca gtagtgaaga aaaatatagt ttcgttaaaa
    34021 cagtacaaac actataaaag agggttttca tttgctttga ttatgggtcc agtggtttct
    34081 tgtgtgctga tggtgttttc actcctgatt aatataaaat taaaaaatga tgatatttgg
    34141 tataggcaat ttttcttttt attatttttc ttctcggcag ggtttgtgat ttcaagtgtt
    34201 ttgaaaaaag gaaatagtcg tggggatatt tattcatttt ttttaataca aaaaagaaaa
    34261 atattttttt tggtacagat gtgtgaaaat atagatatgg aaaaagaaaa aaatatttat
    34321 aaaatatcta attgcttaat taaagagttg gaaaaagaat tgcaatttca agcgaagaaa
    34381 aatagtaata ttttagaagt gttttttgca agcacttttt ggagaaaaat gcaaaatatt
    34441 tttggagaat gttgcatctc caaattggag aaagttgcaa ggcctcggct ggcagctatt
    34501 ctgccagcta catagccatt gcagaccata tttagttgtt atagcgtgag atatggaaac
    34561 ggaagttccg agttttcatc ttcatgtgca tgttccctga aatagcggaa ctcctcatcc
    34621 agctctttat aatggataaa atcatttaga tatctcagat cttcttctgc gcatcggtga
    34681 tcttctatga gatcaagaag ataatcattc atctcctcat agcgttcctg aagattttga
    34741 tattttttct gttctttgat aactttttta tttttagcca ttgttacctg cctcctgact
    34801 gctgattctt gaaagagttg cattgatgct tgattcacgt aaccgattat tgatccccgg
    34861 gaacagaatc agttccacat ggtgggtgag cctgccaatc agtgctgttg tcatccgttg
    34921 gtcataaaga acgttcaccc actgtgagaa ttcaagattc gtgtttaaaa tcaccgattt
    34981 ctgctcgtgt atctcagaaa gataatcaaa cagaagctgt gaaccggtgc ggtcatacgg
    35041 aacatatccg aattcatcca gaatcagtat ccgggcactg ttaagcttct ttttcagtgc
    35101 agtaagcttt ccgctgctct gactctcgga aaagagattg ataagtccgg cagtgcggta
    35161 gaatcttacc ggaatttcct gattacatgc agacattcca atcagaatgg aaagcattgt
    35221 tttaccggtt cctgttcctc catacatgat gacatttttt cctgtatgat aaaactccag
    35281 gtctaacagg ctttggaagc tgacgtcttc cgggaaatct atctcatctg ccctgaattc
    35341 ctccacgcgg tatctacgtg ggaagccggc ggtattgagg aacttgctct tcctttttgc
    35401 tgtacggtat tcaatttcgt ttgtcaggag gtttaaaagg tattcctgcg gtgtgtctcc
    35461 tttctgctcg aaagcctgcc ctgcaaagtt cgtggacagc ttgagctgtt tgcagcatgc
    35521 tgcaatggat ttttctatat cagccatttg agacacctcc cttcttaagg gcggcatcca
    35581 gcattttcag atcatttctg aatggaatga ccttctgctg tggcagtaaa actttgtttt
    35641 caagcggagg cagaagcggt acatctgcat aggttcgcct gtaaaggctc tgcagactgt
    35701 ccggatctgt ggcattcagc cggactgctt cgtcaactgt tctgacagca ctagcaaacc
    35761 cggttctttc cgtaagttct gcaagcacct tcaggacacg tccgcgttcc ttgctttcgc
    35821 atttatccat gtatatctgc atggtttgtg gcatcatgtc atatatgccg ctgtttcgaa
    35881 gagaacgggg tttcctggcg atatatgtaa ggtatggcag ccagtccatt ctttcatgtt
    35941 cattgccgta aaggcgctta tgacgcacca cttcgtgcat atctttgtcc atgacaatca
    36001 catcagagga tgtaatcttg agatttacaa tggactcaca gaaagccggt gaagcagaat
    36061 aacggtgctt tcctgcgtca agagtaaact ttccatattt atccgttgtt gccgttgtgt
    36121 aaagtgccgt atcaaacgga acggaaggaa gcggcagtaa acgagcctta tcttcttcaa
    36181 acagtttact gataaagcgg tcatcatcgt catcatagtg ctcacgctgc atatcgattt
    36241 cacaacgatc cagaagatgc ttgttttctt tcacaagatc atcaaagcgg ggtgccggta
    36301 caagttcgtt gcggcgcagg tagccaacct tgttttccac gtttcctttt tcccatccgg
    36361 attcaggatt cataaaaacc ggcttaatgc ggtagtgttc acaaaagcgt tgaaaccgct
    36421 ctgttacatt acgcccgcca cctttgatga tttcggtaac aatggttctg gtattgtcaa
    36481 accagatttc cgtgggaaca ccaccgatgt gctcaaatat ggcaaccagt ccttccagaa
    36541 gacattccat gttttcgcca taattaagct ggaggaaacc tccgttactg tagggaaaac
    36601 tgagcacaag gtacttagcc tcgtgatgaa gcctgtcatt ttcataaaaa tcggctgttc
    36661 caaagtctga ctgggcttcg ccgggatgat gattaagagg gatatagcca tcggttcttt
    36721 ttagccgtag ttcctctttc ttctgtttga cgtataaggc aacaagccga taactgcagc
    36781 cgaaaccatc tgcttcatcc ttgaggcgtt taaatactct tttggctgta tgccgttgct
    36841 ttcttggtgc aagcttgtct gcctgcagcc attcatcaat caaaggtttg aatgggtcaa
    36901 gcttggattc gtgaacctct gatgatgcag gtttgggaga tggattgtta aagtcctcca
    36961 tatccacata ttttttgacc gttttccagt taaggccggt ctcagatgcg atttcagaaa
    37021 tgttcttatc ttgccggtag aacatatctc tgatatgatg tatctgatcc attgtagttg
    37081 acattctcct ttcctccttg tctttattgt ttggactaca ataaagataa ggttaatggt
    37141 ttttggatat acctgcaatg gatcttttca tgggaatgct catacttggt ggctgccact
    37201 caagcgctac accgttcctg agcgcttcta gcgaatgcct tgcaactttc tccaatttgg
    37261 agatgcaaca ttctccaatt cccgtttgca actttcggta attctatttt acaataaaca
    37321 tttagaagat gctataatgg ttagtgcaat aaatattata ttgatgagat atattatatg
    37381 tggcgatata atagattcct ctacgaaaga actatttgaa tattgcataa atacgttgga
    37441 aacagataaa attcggttta tggaggaaga atgtaaaata ttatttattc atcttatata
    37501 ttatttgaaa tacgaagatg atcatagatg ggaaacgttg attccatatg ctataaatat
    37561 ttttgatgat gatggagtaa accagtatta taaagcgcaa ataaaacaaa tatgttattt
    37621 ggaaaataat ttggaatttc taaatgagag ggagaatata aaaacttcat ctttttggga
    37681 aattgaacat ttgctgaata tacaacaaca agatgagaga aatttgctta aaattttttg
    37741 tgagagtatt aattaatcat aaagcaatct taaatgctgg atgaattaat gattattccg
    37801 ggtttccagc gcattctggt cgcagttcca tagacgcagg aatcatatcc aatggctgtt
    37861 catatgagat ggtgtcagga ttatgaaaat ctaccctgac gacttcctgg ctttccggag
    37921 tgttatagct gcgtccggtt gccgctggta aatccatgca acctttttgc cgtagtcgct
    37981 ttacccagtt ataaaaggtt ccaggcttga tgtcgtgttc cgcacaccat tgatgatctg
    38041 tcaatccact ttgacggcat tccatgatga gacggtattg ttcttcagca ggtattctgt
    38101 aagtgcaaaa tattgctacg ttactcataa attgcgcctg caccaaaatg atagatgcaa
    38161 gcgttttact ctattttagt tttgacagtt agctttcgca gccttgctcc atggggcgaa
    38221 ctgctctaac tgctcatctg acattttatc attcggtcgt tgtgacaaga gatatgtcag
    38281 atatttatag gtattcagat cattcgcttt tgccatctca accatagtat acacaatagc
    38341 actggcggtg gctcctttag gactggcact gaacaaccag ttcttcctgc caacggtgaa
    38401 tggtctgatc gcattctcgc tgagattgtt agaaaaactg cagtggccgt cttccagata
    38461 ggtcatcagg gtgtctttcc gattttgggc atagttcacc gctttcgcca aacgagtccc
    38521 cttgtttggg tgctgttgat ccagccaatc ccagaataca tccagtatcg gcttttcttt
    38581 ttcaagacga aactgttttc tctgctctgc ggtatgattt tttgcttttg agtaccgttc
    38641 acaatcaaac agcttggaac agaactgcac tccctgcact gcgggaagac tataattata
    38701 ctctttcccc ttcggtatgg catctgtgaa gtaacgtctc acatgcgccc aacaagagca
    38761 tcgtttgata tcaggcagat tatgatgacc ttgataccca tccgtttcca gatatccgct
    38821 gaagccttgc aagaatgatt ctgcatggaa ctttgctctt gtctctgtat aatgatagag
    38881 tagaatcggt ggaagaccat cttctccgct gcggaagagc cacatccagg aatctgtttc
    38941 cggattgcgc tccggctcat tcagcacttg aacccgtgtt tcatctgcca tcagatattt
    39001 acgcaccagt aactgacggt gaaaatagtc ataaacatgg cgaagataat tctcggtgca
    39061 gtaaataatc cagttggcaa gcgtagcacg gttcaatggt acacccagtt gtttccagtc
    39121 ctcttcctgc cggtttaacg gcagaccatt ctggtacttc tggtgcatcg cccatgcaac
    39181 gacagattct gatgcataac tttccgggat caacggttcc tgaacaggag ccttgacaaa
    39241 agtctggtca tcgggatgtt ccgctgatat ggcacactcc ggacacttat aggtttcacg
    39301 atagatattt acaactttac ctttggcagg ggtaaagcgg aattcatgac ggacgaattc
    39361 tttcccaata cattccatct gtgttccgca ggctggacag ttccgttcct cctccggaag
    39421 agaaatgatc tcgtcgcagg aaggcacgtt tttaaagagt tcagcgtgag tccgtcttgc
    39481 tttccgctta tgctccggga caatgatgcc atcaggaagt tccggattcc atgccggatc
    39541 cgcttcctgc tcggcttcat caaaaagatt cagctggcct tcgatatcct tccgtttttc
    39601 gctggaagtg ccaaagagct tcttcgtgag atattcaatc tgttgacgaa gagtctcttt
    39661 ttccagacgg tctgcttcca atgtcttttg taaagactgg atcagttctg tctgtgcagc
    39721 aatcgtctta ttcagttggt tgatcatgtc cttatacgca aggatttttg aatcttttga
    39781 attaccagcc atacgttttc tgctccttta tctctgctct tagtatacca caaaaagtga
    39841 agaaaaagaa gcagaaaacc cagtatttac aagggagcaa ggcgctttcc agggtgtgga
    39901 gcgccccgca tttctaccgg attgcagaga agttttccac catcattccg taggtttgaa
    39961 cgctttaggc tgttcgattt caagaccgga catgagccag tcgaattgct gccaggtcag
    40021 ttgttttact tccaactgat ttttcggcca ccggaatctg ccctgaactt ccatgcgttt
    40081 atacaacagc acaaatccat cggattccca gagtaaagct ttgatcctgt cacaacgtct
    40141 tccgcagaaa agatacaggg cactccgtct tggatccatg tgaagttgct cctctacaat
    40201 ggcacacagt ccgtcaatgg atttccgcat atccgttctg cctgttacga tatagatttc
    40261 atcggcgacc gtgatatccc ctaacattcc agctctttca caatgcgaag tgtctgagcc
    40321 agaagctgtg gatctgttcc attcgggata gtcagaagaa accttccaac agacagcttc
    40381 ataggtgctg cctcagaaat gctgcttctt tccatagacg caggaatcat atccaatggc
    40441 tgttcatatg agatggtgtc aggattatga aaatctaccc tgacgacttc ctggctttcc
    40501 ggagtgttat agctgcgtcc ggttgccgct ggtaaatcca tgcaaccttt ttgccgtagt
    40561 cgctttaccc agttataaaa ggttccaggc ttgatgtcgt gttccgcaca ccattgatga
    40621 tctgtcaatc cactttgacg gcattccatg atgagacggt attgttcttc agcaggtatt
    40681 cttttgcttc tcatgagcag tcctccataa atcgaataga gtaaaatgct tgcatctatc
    40741 atttctagca acagaagatg aagtaaaatg cttgcattct ctattaatca ttatggactg
    40801 agttttaggg caacgcaatc cgtcgaattg ttttgcgctt acttatgaaa tacttcctta
    40861 tcactggaaa actaagcttt tttgaggttt tccaaaaaat tatttaaaaa attagcactc
    40921 acctcttggc tcgtttgggg tggttttgtc ctgtggtgtc agagcccgta aagccttatt
    40981 ttacaaggtt tttgcgggtt cttacttttt gtctgagagc gtcaaaaatc gtcatttttt
    41041 gcgaaaatgg tgtagtaaat ggtgtagtag aagagccatg agtgatgtga caagagagtg
    41101 gaaataagag atagaaaaag ggataaagat ttgataaaat taaaattgtt gaagatagat
    41161 ttgaaaattt ttaaaaatac caaggagaaa agagacagaa gaaggcttta taagaaagag
    41221 caagttatag ggcatatata gatttgagac caaggatggg aaaaacaata accaatataa
    41281 ctgtactaga gggagtggcg tatggcaaaa gatgactatc attttgaacg attaacacca
    41341 attaatgata ttgagctgaa agtatatgaa gaggcaatca attatgtatt tgagaaccag
    41401 gatataaaga acgtagctat ttcgggtgca tatagtgcgg gtaaaagcag cgttttggag
    41461 tcatacaaga agaaacatag tgggttacag tttttacata tttctcttgc acattttcaa
    41521 tctccagatt tagaagaaga aacaaaggat gctgacaaaa atgatcatga ggaaaatgaa
    41581 ggagttaaag aatctgtatt agagggaaaa atattgaatc aactgataca ccaaatacct
    41641 tctgataaaa tccctcaaac taattttaga gttaagagaa aaataaagcg atcggatatt
    41701 gcgaaaagca cagtaataat atttatgtta gtgcttatga tactatattt catttttttt
    41761 aaattctgga aaaaatatgt gttatcactg ccggacaata tattgaaatc gattttatcg
    41821 tggtccatta gtcaatatag cctgctgatc agtgggataa tcttgaccat actattaggg
    41881 accgtgattt atggagtggt aaaaatacag aagaataaaa atgtattccg gaaattgaat
    41941 cttcaaggga atgagattga gatatttgaa gagagcaatg attcatattt tgataaatat
    42001 cttaatgaag tgttgtattt gtttgagaat gcagaggttg atgcgattgt ttttgaagat
    42061 atggaccgtt tcaatgtaaa tagtatattt gagcgactgc gagaggtaaa tactcttgta
    42121 aatatccggt tacaaaagga tgataaaaaa attatacgtt ttttctattt gctgcgtgat
    42181 gatatttttg tatcaaaaga tagaacaaag tttttcgact atatcattc
//
