LOCUS       NZ_SHOB01000005        28221 bp    DNA     linear   CON 23-JUN-2024
DEFINITION  Bacillus subtilis strain A1 NODE_5_length_204591_cov_292.348604,
            whole genome shotgun sequence.
ACCESSION   NZ_SHOB01000005
VERSION     NZ_SHOB01000005.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus subtilis
  ORGANISM  Bacillus subtilis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 204591)
  AUTHORS   Babalola,O., Ayangbenro,A.S. and Olanrewaju,O.S.
  TITLE     Draft genome sequence of three rhizospheric plant growth promoting
            bacteria
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 204591)
  AUTHORS   Babalola,O., Ayangbenro,A.S. and Olanrewaju,O.S.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-FEB-2019) Biological Sciences, North-West University,
            South Africa, Corner Albert Luthuli and University Drive, Mafikeng,
            North West Private Bag X2046, South Africa
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. DECEMBER-2018
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 703.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004294565.1-RS_2024_06_23
            Annotation Date                   :: 06/23/2024 03:44:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,243
            CDSs (total)                      :: 4,140
            Genes (coding)                    :: 4,031
            CDSs (with protein)               :: 4,031
            Genes (RNA)                       :: 103
            rRNAs                             :: 8, 6, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 6, 3 (5S, 16S, 23S)
            tRNAs                             :: 81
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 75 of 109
            Pseudo Genes (incomplete)         :: 50 of 109
            Pseudo Genes (internal stop)      :: 23 of 109
            Pseudo Genes (multiple problems)  :: 33 of 109
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:31:26
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 28221
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            SHOB01000005.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..28221
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..28221
                     /SMILES="NC(CCC(=O)O)C(=O)NC(CC(C)C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..28221
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[<0:8221](-)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(<1..8221)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     gene            complement(<1..8221)
                     /gene="srfAA"
                     /locus_tag="ES060_RS19390"
                     /old_locus_tag="ES060_19390"
     CDS             complement(<1..8221)
                     /GO_function="GO:1904091 - non-ribosomal peptide synthetase
                     activity [Evidence IEA]"
                     /NRPS_PKS="Domain: Condensation_Starter (4-303). E-value:
                     6.8e-98. Score: 319.6. Matches aSDomain:
                     nrpspksdomains_ES060_RS19390_Condensation_Starter.1"
                     /NRPS_PKS="Domain: AMP-binding (466-867). E-value:
                     1.1e-112. Score: 368.5. Matches aSDomain:
                     nrpspksdomains_ES060_RS19390_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (976-1044). E-value: 7.2e-25. Score:
                     79.0. Matches aSDomain: nrpspksdomains_ES060_RS19390_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1058-1345). E-value:
                     3.5e-106. Score: 346.5. Matches aSDomain:
                     nrpspksdomains_ES060_RS19390_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1510-1908). E-value:
                     1.8e-109. Score: 358.0. Matches aSDomain:
                     nrpspksdomains_ES060_RS19390_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (2015-2083). E-value: 9.7e-29.
                     Score: 91.4. Matches aSDomain:
                     nrpspksdomains_ES060_RS19390_PCP.2"
                     /NRPS_PKS="Domain: Condensation_LCL (2098-2384). E-value:
                     9.2e-109. Score: 355.0. Matches aSDomain:
                     nrpspksdomains_ES060_RS19390_Condensation_LCL.2"
                     /codon_start=1
                     /gene="srfAA"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1047: phosphopantetheine-binding domain-containing
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388230.2"
                     /locus_tag="ES060_RS19390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ES060_19390"
                     /product="surfactin non-ribosomal peptide synthetase SrfAA"
                     /protein_id="WP_130573373.1"
                     /sec_met_domain="PP-binding (E-value: 2.1e-15, bitscore:
                     50.6, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.3e-121, bitscore:
                     399.6, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 1.2e-98, bitscore:
                     323.4, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEITFYPLTDAQKRIWYTEKFYPHTSISNLAGIGKLVSADAIDYV
                     LVEQAIQEFIRRNEAMRLRLRLDENGEPVQYISEYRPVDIKHTDTTEDPNAIEFISQWS
                     REETKKPLPLYDCDLFRFSLFTIKENEVWFYANVHHVISDGISMNILGNAIMHIYLELA
                     SGSETKEGISHSFIDHVLSEQDYAQSKRFEKDKAFWNKQFESVPELVSLKRNASAGGSL
                     DAERFSKDVPEALHQQILSFCEANKVSVLSVFQSLLAAYLYRVSGQNDVVTGTFMGNRT
                     NAKEKQMLGMFVSTVPLRTNIDGGQAFLEFVKDRMKDLMKTLRHQKYPYNLLINDLRET
                     KSSLTKLFTVSLEYQVMQWQKEEDLAFLTEPIFSGSGLNDVSIHVKDRWDTGKLTIDFD
                     YRTDLFSREEINMICERMITMLENALTHPEHTIDELTMISDAEKEKLLARAGGKSVSYR
                     KDMTIPELFQEKAEQLSDHPAVVFEDRTLSYRTLHEQSARIANVLKQKGVGPDSPVAVL
                     IERSERMITAIMGILKAGGAYVPIDPGFPAERIQYILEDCGADFILTESKVAAPEADAE
                     LIDLDQAIAEGAEESLNADVNARNLAYIIYTSGTTGRPKGVMIEHRQVHHLVESLQQTI
                     YQSGSQTLRMALLAPFHFDASVKQIFASLLLGQTLYIVPKKTVTNGAALTAYYRRNSIE
                     ATDGTPAHLQMLVAAGDFEGLKLKHMLIGGEGLSSVVADKLLKLFKEAGTAPRLTNVYG
                     PTETCVDASVHPVIPEIAVQSAYVPIGKALGNNRLYILDQKGRLQPEGVAGELYIAGAG
                     VGRGYLHLPELTEEKFLQDPFVPGDRMYRTGDVVRWLPDGTIEYLGREDDQVKVRGYRI
                     ELGEIEAVIQQAPDVAKAVVLARPDEQGNLEVCAYVVQKPESEFAPAGLRAHAARQLPD
                     YMVPAYFTEVTEIPLTPSGKVDRRKLFALEVKAVSGTAYTAPRNETEKAIAAIWQDVLN
                     VEKAGIFDNFFETGGHSLKAMTLLTKIHKQTGVEIPLQYLFEHPTIAALAEEADHRESR
                     AFSVIEPAEKQEHYPLSLAQQRTYIVSQFEDAGVGYNMPAAAILEGPLDIQKLERAFQG
                     LIRRHESLRTSFVLENSTPRQNIHDSVDFNIEMIERGGRSDEAIMASFVRKFDLAKAPL
                     FRIGLLGLEENRHMLLFDMHHLISDGVSIGIMLEELARIYKGEQLPELRLQYKDYAVWQ
                     SRQAAEGYKKDQAYWKEVFAGELPVLQLLSDYPRPPVQSFEGDRVSIKLDAGVKDRLNR
                     LAEQNGATLYMVMLSAYYTLLSKYTGQDDIIVGTPSAGRNHSDTEGIVGMFVNTLAIRS
                     EVKQDETFTQLISRVRKQVLNAFSHQDYPFEWLVEDLNIPRDVSRHPLFDTMFSLQNAT
                     EGIPAVGDLSLSVHETNFKIAKFDLTVQARETDEGIELDLDYSTKLFKQSTANRLLTHF
                     ARLLEDAAADPEKPISEYKLLSEEAAASQIQQFNPGRTPYPKDKTIVQLFEEQAANTPD
                     HTALQYEGESLTYRELNERANRLARGILSLGAGEGRTAAVLCERSMDMIVSILAVLKSG
                     SAYVPIDPEHPIQRMQHFFRDSGAKVLLTQRKLKALAEEAEFKGVIVLADEEESYHADA
                     RNLALPLDSAAMANLTYTSGTTGTPKGNIVTHANILRTVKGTNYLSITEQDTILGLSNY
                     VFDAFMFDMFGSLLNGAKLVLIPKETVLDMARLSRVIERENISILMITTALFHLLVDLN
                     PACLSTLRKIMFGGERASVEHVRKALQTVGKGKLLHMYGPSESTVFATYHPVDELEEHT
                     LSVPIGKPVSNTEVYILDRTGHVQPAGIAGELCVSGEGLVKGYYNRPELTEEKFVPHPF
                     TSGERMYKTGDLARWLPNGDIEFIGRIDHQVKIRGQRIELGEIEHQLQTHDRVQESVVL
                     AVDQGAGDKLLCAYYVGAGDISSQEMREHAAKDLPAYMVPAVFIQMDELPLTGNGKIDR
                     RALPIPDANVSRGVSYVAPRNETEQKVADIWAHVLQAEQVGAYDHFFDIGGHSLAGMKM
                     LALVHQELGVELSLKDLFQSPTVEGLAQVTASAEKGTAASISPAEKQDTYPVSSPQKRM
                     YVLQQLEDAQTSYNMPAVLRLTGELDVERLNSVMQQLMQRHEALRTTFEIKDGETVQRI
                     WEEAECEIAYFEAPEEERERIVSEFIKPFKIDQLPLFRIGLIKHSDTEHVLLFDMHHII
                     SDGASVGVLIEELSKLYDGETLEPLRIQYKDYAVWQQQFIQSELYKKQEEHWLKELDGE
                     LPVLTLPTDYSRPAVQTFEGDRIAFSLEAGKADALRRLAKETDSTLYMVLLASYSAFLS
                     KLSGQDDIIVGSPVAGRSQADVSRVIGMFVNTLALRTYPKGEKTFANYLNEVKETALSA
                     FDAQDYPLEDLIGNVQVQRDTSRNPLFDAVFSMQNANIKDLTMKGIQLEPHPFERKTAK
                     FDLTLTADETDGGLTFVLEYNTALFKQETIERWKQYWMELLDAVTGNPNQPLSSLSLVT
                     ETEKQALLEAWKGKALPVPTDKTVHQLFEETVQRHKNRPAVTYNGQSWTYGELNAKANR
                     LARILMDCGISPDDRVGVLTKPSLEMSAAVLGVLKAGAAFVPIDPDYPDQRIEYILQDS
                     GAKLLLKQEGISVPDSYTGDVILLDGSRTILSLPLDENDEGNPETAVTAENLAYMIYTS
                     GTTGQPKGVMVEHHALVNLCFWHHDAFGMTAEDRSAKYAG"
     CDS_motif       complement(83..142)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ES060_RS19390_0027"
                     /evalue="2.30E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="ES060_RS19390"
                     /protein_end="2713"
                     /protein_start="2693"
                     /score="32.3"
                     /tool="antismash"
                     /translation="AYMIYTSGTTGQPKGVMVEH"
     CDS_motif       complement(344..385)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ES060_RS19390_0026"
                     /evalue="3.00E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="ES060_RS19390"
                     /protein_end="2626"
                     /protein_start="2612"
                     /score="17.2"
                     /tool="antismash"
                     /translation="LGVLKAGAAFVPID"
     CDS_motif       complement(908..1027)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ES060_RS19390_0025"
                     /evalue="2.30E-12"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ES060_RS19390"
                     /protein_end="2438"
                     /protein_start="2398"
                     /score="39.2"
                     /tool="antismash"
                     /translation="KETALSAFDAQDYPLEDLIGNVQVQRDTSRNPLFDAVFSM"
     aSDomain        complement(1070..1927)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ES060_RS19390_Condensation_LCL.2
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="9.20E-109"
                     /label="ES060_RS19390_Condensation_LCL.2"
                     /locus_tag="ES060_RS19390"
                     /protein_end="2384"
                     /protein_start="2098"
                     /score="355.0"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIISDG"
                     /tool="antismash"
                     /translation="DTYPVSSPQKRMYVLQQLEDAQTSYNMPAVLRLTGELDVERLNSV
                     MQQLMQRHEALRTTFEIKDGETVQRIWEEAECEIAYFEAPEEERERIVSEFIKPFKIDQ
                     LPLFRIGLIKHSDTEHVLLFDMHHIISDGASVGVLIEELSKLYDGETLEPLRIQYKDYA
                     VWQQQFIQSELYKKQEEHWLKELDGELPVLTLPTDYSRPAVQTFEGDRIAFSLEAGKAD
                     ALRRLAKETDSTLYMVLLASYSAFLSKLSGQDDIIVGSPVAGRSQADVSRVIGMFVNTL
                     ALRTY"
     CDS_motif       complement(1076..1165)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ES060_RS19390_0024"
                     /evalue="4.00E-14"
                     /label="C5_LCL_267-296"
                     /locus_tag="ES060_RS19390"
                     /protein_end="2382"
                     /protein_start="2352"
                     /score="44.9"
                     /tool="antismash"
                     /translation="DIIVGSPVAGRSQADVSRVIGMFVNTLALR"
     CDS_motif       complement(1424..1456)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ES060_RS19390_0023"
                     /evalue="3.10E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="ES060_RS19390"
                     /protein_end="2266"
                     /protein_start="2255"
                     /score="13.4"
                     /tool="antismash"
                     /translation="QYKDYAVWQQQ"
     CDS_motif       complement(1487..1552)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ES060_RS19390_0022"
                     /evalue="7.10E-10"
                     /label="C3_LCL_132-143"
                     /locus_tag="ES060_RS19390"
                     /protein_end="2245"
                     /protein_start="2223"
                     /score="31.4"
                     /tool="antismash"
                     /translation="MHHIISDGASVGVLIEELSKLY"
     CDS_motif       complement(1748..1861)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ES060_RS19390_0021"
                     /evalue="3.50E-18"
                     /label="C2_LCL_024-062"
                     /locus_tag="ES060_RS19390"
                     /protein_end="2158"
                     /protein_start="2120"
                     /score="58.0"
                     /tool="antismash"
                     /translation="TSYNMPAVLRLTGELDVERLNSVMQQLMQRHEALRTTF"
     aSDomain        complement(1973..2176)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ES060_RS19390_PCP.2"
                     /evalue="9.70E-29"
                     /label="ES060_RS19390_PCP.2"
                     /locus_tag="ES060_RS19390"
                     /protein_end="2083"
                     /protein_start="2015"
                     /score="91.4"
                     /tool="antismash"
                     /translation="EQKVADIWAHVLQAEQVGAYDHFFDIGGHSLAGMKMLALVHQELG
                     VELSLKDLFQSPTVEGLAQVTAS"
     aSModule        complement(1973..5047)
                     /complete
                     /domains="nrpspksdomains_ES060_RS19390_Condensation_LCL.1"
                     /domains="nrpspksdomains_ES060_RS19390_AMP-binding.2"
                     /domains="nrpspksdomains_ES060_RS19390_PCP.2"
                     /locus_tags="ES060_RS19390"
                     /monomer_pairings="Leu -> Leu"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(2468..2533)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ES060_RS19390_0020"
                     /evalue="4.20E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ES060_RS19390"
                     /protein_end="1918"
                     /protein_start="1896"
                     /score="37.9"
                     /tool="antismash"
                     /translation="FIGRIDHQVKIRGQRIELGEIE"
     aSDomain        complement(2498..3691)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ES060_RS19390_AMP-binding.2"
                     /evalue="1.80E-109"
                     /label="ES060_RS19390_AMP-binding.2"
                     /locus_tag="ES060_RS19390"
                     /protein_end="1908"
                     /protein_start="1510"
                     /score="358.0"
                     /specificity="substrate consensus: Leu"
                     /tool="antismash"
                     /translation="FEEQAANTPDHTALQYEGESLTYRELNERANRLARGILSLGAGEG
                     RTAAVLCERSMDMIVSILAVLKSGSAYVPIDPEHPIQRMQHFFRDSGAKVLLTQRKLKA
                     LAEEAEFKGVIVLADEEESYHADARNLALPLDSAAMANLTYTSGTTGTPKGNIVTHANI
                     LRTVKGTNYLSITEQDTILGLSNYVFDAFMFDMFGSLLNGAKLVLIPKETVLDMARLSR
                     VIERENISILMITTALFHLLVDLNPACLSTLRKIMFGGERASVEHVRKALQTVGKGKLL
                     HMYGPSESTVFATYHPVDELEEHTLSVPIGKPVSNTEVYILDRTGHVQPAGIAGELCVS
                     GEGLVKGYYNRPELTEEKFVPHPFTSGERMYKTGDLARWLPNGDIEFIGRIDHQVKIR"
     CDS_motif       complement(2615..2704)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ES060_RS19390_0019"
                     /evalue="2.20E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="ES060_RS19390"
                     /protein_end="1869"
                     /protein_start="1839"
                     /score="42.3"
                     /tool="antismash"
                     /translation="PAGIAGELCVSGEGLVKGYYNRPELTEEKF"
     CDS_motif       complement(2819..2842)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ES060_RS19390_0018"
                     /evalue="8.70E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="ES060_RS19390"
                     /protein_end="1801"
                     /protein_start="1793"
                     /score="3.3"
                     /tool="antismash"
                     /translation="YGPSESTV"
     CDS_motif       complement(3212..3265)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ES060_RS19390_0017"
                     /evalue="6.90E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="ES060_RS19390"
                     /protein_end="1670"
                     /protein_start="1652"
                     /score="18.7"
                     /tool="antismash"
                     /translation="LTYTSGTTGTPKGNIVTH"
     CDS_motif       complement(3464..3505)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ES060_RS19390_0016"
                     /evalue="2.40E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="ES060_RS19390"
                     /protein_end="1586"
                     /protein_start="1572"
                     /score="14.5"
                     /tool="antismash"
                     /translation="LAVLKSGSAYVPID"
     CDS_motif       complement(4028..4147)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ES060_RS19390_0015"
                     /evalue="3.40E-20"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ES060_RS19390"
                     /protein_end="1398"
                     /protein_start="1358"
                     /score="64.5"
                     /tool="antismash"
                     /translation="RKQVLNAFSHQDYPFEWLVEDLNIPRDVSRHPLFDTMFSL"
     aSDomain        complement(4187..5047)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ES060_RS19390_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="3.50E-106"
                     /label="ES060_RS19390_Condensation_LCL.1"
                     /locus_tag="ES060_RS19390"
                     /protein_end="1345"
                     /protein_start="1058"
                     /score="346.5"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHLISDG"
                     /tool="antismash"
                     /translation="QEHYPLSLAQQRTYIVSQFEDAGVGYNMPAAAILEGPLDIQKLER
                     AFQGLIRRHESLRTSFVLENSTPRQNIHDSVDFNIEMIERGGRSDEAIMASFVRKFDLA
                     KAPLFRIGLLGLEENRHMLLFDMHHLISDGVSIGIMLEELARIYKGEQLPELRLQYKDY
                     AVWQSRQAAEGYKKDQAYWKEVFAGELPVLQLLSDYPRPPVQSFEGDRVSIKLDAGVKD
                     RLNRLAEQNGATLYMVMLSAYYTLLSKYTGQDDIIVGTPSAGRNHSDTEGIVGMFVNTL
                     AIRSEV"
     CDS_motif       complement(4196..4285)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ES060_RS19390_0014"
                     /evalue="4.00E-15"
                     /label="C5_LCL_267-296"
                     /locus_tag="ES060_RS19390"
                     /protein_end="1342"
                     /protein_start="1312"
                     /score="48.1"
                     /tool="antismash"
                     /translation="DIIVGTPSAGRNHSDTEGIVGMFVNTLAIR"
     CDS_motif       complement(4541..4573)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ES060_RS19390_0013"
                     /evalue="6.70E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="ES060_RS19390"
                     /protein_end="1227"
                     /protein_start="1216"
                     /score="12.4"
                     /tool="antismash"
                     /translation="QYKDYAVWQSR"
     CDS_motif       complement(4604..4669)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ES060_RS19390_0012"
                     /evalue="1.80E-08"
                     /label="C3_LCL_132-143"
                     /locus_tag="ES060_RS19390"
                     /protein_end="1206"
                     /protein_start="1184"
                     /score="26.9"
                     /tool="antismash"
                     /translation="MHHLISDGVSIGIMLEELARIY"
     CDS_motif       complement(4862..4972)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ES060_RS19390_0011"
                     /evalue="4.50E-17"
                     /label="C2_LCL_024-062"
                     /locus_tag="ES060_RS19390"
                     /protein_end="1120"
                     /protein_start="1083"
                     /score="54.4"
                     /tool="antismash"
                     /translation="YNMPAAAILEGPLDIQKLERAFQGLIRRHESLRTSFV"
     aSDomain        complement(5090..5293)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ES060_RS19390_PCP.1"
                     /evalue="7.20E-25"
                     /label="ES060_RS19390_PCP.1"
                     /locus_tag="ES060_RS19390"
                     /protein_end="1044"
                     /protein_start="976"
                     /score="79.0"
                     /tool="antismash"
                     /translation="EKAIAAIWQDVLNVEKAGIFDNFFETGGHSLKAMTLLTKIHKQTG
                     VEIPLQYLFEHPTIAALAEEADH"
     aSModule        complement(5090..8209)
                     /complete
                     /domains="nrpspksdomains_ES060_RS19390_Condensation_Starter
                     .1"
                     /domains="nrpspksdomains_ES060_RS19390_AMP-binding.1"
                     /domains="nrpspksdomains_ES060_RS19390_PCP.1"
                     /locus_tags="ES060_RS19390"
                     /monomer_pairings="Glu -> Glu"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(5591..5656)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ES060_RS19390_0010"
                     /evalue="4.00E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ES060_RS19390"
                     /protein_end="877"
                     /protein_start="855"
                     /score="38.0"
                     /tool="antismash"
                     /translation="YLGREDDQVKVRGYRIELGEIE"
     aSDomain        complement(5621..6823)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ES060_RS19390_AMP-binding.1"
                     /evalue="1.10E-112"
                     /label="ES060_RS19390_AMP-binding.1"
                     /locus_tag="ES060_RS19390"
                     /protein_end="867"
                     /protein_start="466"
                     /score="368.5"
                     /specificity="substrate consensus: Glu"
                     /tool="antismash"
                     /translation="FQEKAEQLSDHPAVVFEDRTLSYRTLHEQSARIANVLKQKGVGPD
                     SPVAVLIERSERMITAIMGILKAGGAYVPIDPGFPAERIQYILEDCGADFILTESKVAA
                     PEADAELIDLDQAIAEGAEESLNADVNARNLAYIIYTSGTTGRPKGVMIEHRQVHHLVE
                     SLQQTIYQSGSQTLRMALLAPFHFDASVKQIFASLLLGQTLYIVPKKTVTNGAALTAYY
                     RRNSIEATDGTPAHLQMLVAAGDFEGLKLKHMLIGGEGLSSVVADKLLKLFKEAGTAPR
                     LTNVYGPTETCVDASVHPVIPEIAVQSAYVPIGKALGNNRLYILDQKGRLQPEGVAGEL
                     YIAGAGVGRGYLHLPELTEEKFLQDPFVPGDRMYRTGDVVRWLPDGTIEYLGREDDQVK
                     VR"
     CDS_motif       complement(5738..5827)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ES060_RS19390_0009"
                     /evalue="7.30E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="ES060_RS19390"
                     /protein_end="828"
                     /protein_start="798"
                     /score="47.1"
                     /tool="antismash"
                     /translation="PEGVAGELYIAGAGVGRGYLHLPELTEEKF"
     CDS_motif       complement(5945..5968)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ES060_RS19390_0008"
                     /evalue="1.30E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="ES060_RS19390"
                     /protein_end="759"
                     /protein_start="751"
                     /score="5.6"
                     /tool="antismash"
                     /translation="YGPTETCV"
     CDS_motif       complement(6359..6418)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ES060_RS19390_0007"
                     /evalue="8.00E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ES060_RS19390"
                     /protein_end="621"
                     /protein_start="601"
                     /score="33.7"
                     /tool="antismash"
                     /translation="AYIIYTSGTTGRPKGVMIEH"
     CDS_motif       complement(6596..6637)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ES060_RS19390_0006"
                     /evalue="2.10E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="ES060_RS19390"
                     /protein_end="542"
                     /protein_start="528"
                     /score="17.7"
                     /tool="antismash"
                     /translation="MGILKAGGAYVPID"
     CDS_motif       complement(7160..7273)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ES060_RS19390_0005"
                     /evalue="7.00E-10"
                     /label="C67_starter_14fromHMM"
                     /locus_tag="ES060_RS19390"
                     /protein_end="354"
                     /protein_start="316"
                     /score="31.5"
                     /tool="antismash"
                     /translation="KDLMKTLRHQKYPYNLLINDLRETKSSLTKLFTVSLEY"
     aSDomain        complement(7313..8209)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ES060_RS19390_Condensation_Start
                     er.1"
                     /domain_subtypes="Condensation_Starter"
                     /evalue="6.80E-98"
                     /label="ES060_RS19390_Condensation_Starter.1"
                     /locus_tag="ES060_RS19390"
                     /protein_end="303"
                     /protein_start="4"
                     /score="319.6"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHVISDG"
                     /tool="antismash"
                     /translation="FYPLTDAQKRIWYTEKFYPHTSISNLAGIGKLVSADAIDYVLVEQ
                     AIQEFIRRNEAMRLRLRLDENGEPVQYISEYRPVDIKHTDTTEDPNAIEFISQWSREET
                     KKPLPLYDCDLFRFSLFTIKENEVWFYANVHHVISDGISMNILGNAIMHIYLELASGSE
                     TKEGISHSFIDHVLSEQDYAQSKRFEKDKAFWNKQFESVPELVSLKRNASAGGSLDAER
                     FSKDVPEALHQQILSFCEANKVSVLSVFQSLLAAYLYRVSGQNDVVTGTFMGNRTNAKE
                     KQMLGMFVSTVPLRTNID"
     CDS_motif       complement(7325..7414)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ES060_RS19390_0004"
                     /evalue="1.00E-11"
                     /label="C5_starter_265-294"
                     /locus_tag="ES060_RS19390"
                     /protein_end="299"
                     /protein_start="269"
                     /score="37.2"
                     /tool="antismash"
                     /translation="DVVTGTFMGNRTNAKEKQMLGMFVSTVPLR"
     CDS_motif       complement(7745..7810)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ES060_RS19390_0003"
                     /evalue="1.80E-06"
                     /label="C3_LCL_132-143"
                     /locus_tag="ES060_RS19390"
                     /protein_end="159"
                     /protein_start="137"
                     /score="20.6"
                     /tool="antismash"
                     /translation="VHHVISDGISMNILGNAIMHIY"
     CDS_motif       complement(8024..8143)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ES060_RS19390_0002"
                     /evalue="2.50E-06"
                     /label="C2_starter_024-063"
                     /locus_tag="ES060_RS19390"
                     /protein_end="66"
                     /protein_start="26"
                     /score="20.1"
                     /tool="antismash"
                     /translation="ISNLAGIGKLVSADAIDYVLVEQAIQEFIRRNEAMRLRLR"
     CDS_motif       complement(8168..8206)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ES060_RS19390_0001"
                     /evalue="7.10E-03"
                     /label="C1_starter_004-017"
                     /locus_tag="ES060_RS19390"
                     /protein_end="18"
                     /protein_start="5"
                     /score="9.4"
                     /tool="antismash"
                     /translation="YPLTDAQKRIWYT"
     misc_feature    complement(8648..8662)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.42"
                     /tool="antismash"
     misc_feature    8667..8680
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.77"
                     /tool="antismash"
     misc_feature    8711..8723
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 20.5"
                     /tool="antismash"
     gene            complement(8798..9160)
                     /gene="hxlR"
                     /locus_tag="ES060_RS19395"
                     /old_locus_tag="ES060_19395"
     CDS             complement(8798..9160)
                     /codon_start=1
                     /gene="hxlR"
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388229.2"
                     /locus_tag="ES060_RS19395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ES060_19395"
                     /product="transcriptional activator HxlR"
                     /protein_id="WP_003246265.1"
                     /transl_table=11
                     /translation="MSRMDDKRFNCEKELTLAVIGGKWKMLILWHLGKEGTKRFNELKT
                     LIPDITQKILVNQLRELEQDMIVHREVYPVVPPKVEYSLTPHGESLMPILEAMYEWGKG
                     YMELIDIDKNVMKESL"
     gene            9393..10025
                     /gene="hxlA"
                     /locus_tag="ES060_RS19400"
                     /old_locus_tag="ES060_19400"
     CDS             9393..10025
                     /EC_number="4.1.2.43"
                     /GO_function="GO:0043801 - hexulose-6-phosphate synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0019647 - formaldehyde assimilation via
                     ribulose monophosphate cycle [Evidence IEA]"
                     /codon_start=1
                     /gene="hxlA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388228.1"
                     /locus_tag="ES060_RS19400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ES060_19400"
                     /product="3-hexulose-6-phosphate synthase"
                     /protein_id="WP_130573374.1"
                     /transl_table=11
                     /translation="MELQLALDLVNIPEAIELVKEVEQYIDVVEIGTPVVINEGLRAVK
                     EIKEAFPQLKVLADLKIMDAGGYEIMKASEAGADIITVLGATDDATIKGAVEEAKKQKK
                     KILVDMINVKDIESRAKEIDALGVDYICVHTGYDLQAEGKNSFEELTTIKNTVKNAKTA
                     IAGGIKLDTLPEVIKQNPDLIIVGGGITSAADKAETASKMKQLIVQG"
     gene            10031..10588
                     /gene="hxlB"
                     /locus_tag="ES060_RS19405"
                     /old_locus_tag="ES060_19405"
     CDS             10031..10588
                     /EC_number="5.3.1.27"
                     /GO_function="GO:0043800 - hexulose-6-phosphate isomerase
                     activity [Evidence IEA]"
                     /GO_process="GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="hxlB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388227.1"
                     /locus_tag="ES060_RS19405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ES060_19405"
                     /product="6-phospho-3-hexuloisomerase"
                     /protein_id="WP_130573375.1"
                     /transl_table=11
                     /translation="MKTTEYVAEILNELHRSAAYIANEEADQLADHILSSHQIFTAGAG
                     RSGLMAKSFAMRLMHMGFNAHIVGEILTPPLAKGDLVIIGSGSGETKSLIHTAAKAKSL
                     HGIVAALTINPESSIGKQADLIIRMPGSPKDQSNGSYKTIQPMGSLFEQTLLLFYDAVI
                     LKLMEKKGLDSETMFTHHANLE"
     gene            10699..12420
                     /gene="tlpC"
                     /locus_tag="ES060_RS19410"
                     /old_locus_tag="ES060_19410"
     CDS             10699..12420
                     /GO_function="GO:0004888 - transmembrane signaling receptor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="tlpC"
                     /gene_functions="other (smcogs) SMCOG1061: methyl-accepting
                     chemotaxis protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388226.2"
                     /locus_tag="ES060_RS19410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ES060_19410"
                     /product="methyl-accepting chemotaxis protein TlpC"
                     /protein_id="WP_130573376.1"
                     /transl_table=11
                     /translation="MLIKRLEMKLGTKILCLVFVVILLFSASVGTVMLKEITESMKQMA
                     TEKAKGDLALSSTYIDDVMSGDWQVKNNKLYKGQTQINGNEDIVDLLGEKTGDTITIFQ
                     GDTRVATNVMKNGERAVGTQASSEVIAAVLKKGKRFYGQADVAGSSYQTAYMPLKDQNG
                     NIIGMLYTGANQSILTSLTQSLFTQFAIVLVIVIMVSVILVLVFTRKINKRLNALKSAF
                     ESAGNGDMTIEVSDKTGDELSELSVYYNKMRMKLNDTIQTVQQSALQLASASQQLSAGA
                     EETNQASEKITEAVQQIANGAQDQITRIENSESSLKQASADIRDISANTAAIADKGQLA
                     QSKADIGQKEIANVQAQMDAIHQSIQKSGEIIHQLDGRSKQIEQILSVITQIADQTNLL
                     ALNAAIEAARAGEQGKGFAVVADEVRKLAEESQQSAGQISKLIIEIQKDMNRSARSVEH
                     VKTEAAEGVTMIQRTRDAFKEIAAATGEISAEISDLSASVTNISASAHQINDSFAANTA
                     DIKESTKNTRQAAALTEEQFAAMEEITAASETLSQLAEELTGIISQFKMINQAENG"
     misc_feature    12429..12442
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 21.98"
                     /tool="antismash"
     gene            12588..13037
                     /gene="nucA"
                     /locus_tag="ES060_RS19415"
                     /old_locus_tag="ES060_19415"
     CDS             12588..13037
                     /EC_number="3.-.-.-"
                     /codon_start=1
                     /gene="nucA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388225.3"
                     /locus_tag="ES060_RS19415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ES060_19415"
                     /product="DNA-entry nuclease"
                     /protein_id="WP_124060108.1"
                     /transl_table=11
                     /translation="MNITTDIIKTILLVIVIIAAAAVGLIKGDFFSADQKTSQTKEYDE
                     TISFPSDRYPETAKHIKDAINEGHSEVCTIDRDGAEERREQSLKDVPSKKGYDRDEWPM
                     AMCKEGGEGASVEYISPADNRGAGSWVGHQLTDYPDGTKVLFTIQ"
     gene            13064..13462
                     /gene="nin"
                     /locus_tag="ES060_RS19420"
                     /old_locus_tag="ES060_19420"
     CDS             13064..13462
                     /codon_start=1
                     /gene="nin"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388224.1"
                     /locus_tag="ES060_RS19420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ES060_19420"
                     /product="DNA-entry nuclease inhibitor"
                     /protein_id="WP_015252845.1"
                     /transl_table=11
                     /translation="MIKSWKPQELSISYHQFTVFQKDSTPPVMDWTDEAIEKGYAAADG
                     AISFEAQRNTKAFILLRLNSSETVNSYETKVTVPFHVTENGIHIESIMSKRLSFDLPKG
                     DYQLTCWTVPAEMSDLHADTYIIDAVSV"
     gene            complement(13499..14932)
                     /gene="bglC"
                     /locus_tag="ES060_RS19425"
                     /old_locus_tag="ES060_19425"
     CDS             complement(13499..14932)
                     /EC_number="3.2.1.86"
                     /codon_start=1
                     /gene="bglC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388223.1"
                     /locus_tag="ES060_RS19425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ES060_19425"
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="WP_130573377.1"
                     /transl_table=11
                     /translation="MIHQHPESFPKHFLWGSASAAYQIEGAWNEDGKGPSVWDVFTKIP
                     GKTFKGTDGEIAVDHYHRFKEDVALMAEMGLKAYRFSVSWPRVFPKGKGEINEAGLAFY
                     DSLIDELLSHHIEPVLTLYHWDLPQALMDEYGGFESRNIIEDFNHYCITLYKRFGDRVK
                     YWVTLNEQNYNFNHGFITAMHPPGVKDRKRFYEANHIAFLANAKAIESFREYVPEGKIG
                     PSFAYSPAYPLSSHPEDILAFENAEEFMNNWWLDMYCWGTYPQIPFRYLEKQGWAPKIE
                     AGDMELLAKGKPDFVGVNYYQTITYERNPLDGVSEGKMNTTGQKGTNQETGIPGVFKTK
                     KNPHLTTSNWDWTIDPIGLRIGLRRITSRYQLPVFITENGLGEFDKVEDGTVQDDYRID
                     YLRSHLEQCRQAISDGVDLIGYCSWSFTDLLSWLNGYQKRYGFVYVNRDEVSTYDLKRL
                     KKKSFYWYQDVIKTNGESL"
     misc_feature    14960..14980
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 25.59"
                     /tool="antismash"
     misc_feature    complement(15068..15081)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 20.67"
                     /tool="antismash"
     gene            complement(15084..15416)
                     /gene="yckD"
                     /locus_tag="ES060_RS19430"
                     /old_locus_tag="ES060_19430"
     CDS             complement(15084..15416)
                     /codon_start=1
                     /gene="yckD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388222.1"
                     /locus_tag="ES060_RS19430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ES060_19430"
                     /product="YckD family protein"
                     /protein_id="WP_015252849.1"
                     /transl_table=11
                     /translation="MKRITINIITMFIAAAVISLTGTAEAAEKQQQPPANVTLTDQQKK
                     EIEQLEAEILKKRKDVISKYVQYGILPKERGEHIKNHLDKHFEMMKQNGFVPKHHPHPH
                     KFEKRH"
     gene            complement(15498..15953)
                     /gene="yckC"
                     /locus_tag="ES060_RS19435"
                     /old_locus_tag="ES060_19435"
     CDS             complement(15498..15953)
                     /codon_start=1
                     /gene="yckC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388221.1"
                     /locus_tag="ES060_RS19435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ES060_19435"
                     /product="RDD family protein"
                     /protein_id="WP_064672016.1"
                     /transl_table=11
                     /translation="MNIYKPAGFWIRLGAALLDYIIVSVPLLLIYWLITGKDPNDSMFI
                     SLVVLLYSILLPVFWRGYLIGKRICGIRIVKKDGSQVSLLTMFLRVIVAGLVYVITFGL
                     GLIASLILIAVREDKRTLHDLIAGTYVTYATPGEEELNADEEIRKSE"
     gene            complement(15972..16168)
                     /locus_tag="ES060_RS19440"
                     /old_locus_tag="ES060_19440"
                     /pseudo=""
     CDS             complement(15972..16168)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009513942.1"
                     /locus_tag="ES060_RS19440"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="ES060_19440"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSKDECPTYQGNTCGREGCSRSVIPLCQYRKKWSEA"
     gene            16329..17192
                     /gene="yckB"
                     /locus_tag="ES060_RS19445"
                     /old_locus_tag="ES060_19445"
     CDS             16329..17192
                     /codon_start=1
                     /gene="yckB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388220.1"
                     /locus_tag="ES060_RS19445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ES060_19445"
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="WP_086343439.1"
                     /transl_table=11
                     /translation="MKSFKQSKAVIFSFTMAFFLILAACSGKNEADSKDTGWEQIKDKG
                     KIVVATSGTLYPTSYHDTDSGSDKLTGYEVEVVREAAKRLGLKVEFKEMGIDGMLTAVN
                     SGQVDAAANDIDVTKDREKKFAFSTPYKYSYGTAIVRKDDLSGIKTLKDLKGKKAAGAA
                     TTVYMDVARKYGAKEVIYDNATNEQYLKDVANGRTDVILNDYYLQTLALAAFPDLNITI
                     HPDIKYMPNKQALVMKKSNEALQKKMNEALKEMSKDGSLTKLSKQFFNKADVSKKIDAD
                     VQDVDL"
     gene            17202..17882
                     /gene="yckA"
                     /locus_tag="ES060_RS19450"
                     /old_locus_tag="ES060_19450"
     CDS             17202..17882
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="yckA"
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388219.1"
                     /locus_tag="ES060_RS19450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ES060_19450"
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_024572176.1"
                     /transl_table=11
                     /translation="MINSIQWEYIFNTKLAIESFPYVIKGIGYTLLISFVSMFAGTVIG
                     LFISLARMSKLALLRWPAKLYISFMRGVPILVILFILYFGFPYIGIQFSAVTAALIGFS
                     LNSAAYIAEINRSAISSVEKGQWEAASSLGLSYWQTMRGIILPQSIRIALPPLANVLLD
                     LIKASSLAAMITVPELLQHAKIIGGREFDYMTMYILTALIYWAICSIAAVFQNILEKKY
                     AHYV"
     gene            complement(17931..19124)
                     /gene="zinU"
                     /gene_synonym="yciC"
                     /locus_tag="ES060_RS19455"
                     /old_locus_tag="ES060_19455"
     CDS             complement(17931..19124)
                     /codon_start=1
                     /gene="zinU"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1178: cobalamin synthesis protein/P47K family protein"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="yciC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388218.1"
                     /locus_tag="ES060_RS19455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ES060_19455"
                     /product="zinc metallochaperone ZinU"
                     /protein_id="WP_024572175.1"
                     /transl_table=11
                     /translation="MKKIPVTVLSGYLGAGKTTLLNSILQNREGLKIAVIVNDMSEVNI
                     DAGLVKQEGGLSRTDEKLVEMSNGCICCTLREDLLIEVEKLAKDGRFDYIVIESTGISE
                     PIPVAQTFSYIDEEMGIDLTKFCQLDTMVTVVDANRFWHDYQSGESLLDRKEALGEEDE
                     REIADLLIDQIEFCDVLILNKCDLVSEQELEQLEKVLRKLQPRAKFIRSVKGNVKPQEI
                     LHTGLFNFEEASGSAGWIQELTAGHAEHTPETEEYGISSFVYKRRLPFHSTRFYQWIDQ
                     MPKNVVRAKGIVWCASHNNLALLMSQAGPSVTIEPVSYWVAALPKLEQEQVKQQEPEIL
                     EEWDPEFGDRLTQLVFIGTDLDEETITKELDQCLLTEYEFDSDWSLFEDPFKWKLNQ"
     gene            complement(19152..19340)
                     /locus_tag="ES060_RS19460"
                     /old_locus_tag="ES060_19460"
                     /pseudo=""
     CDS             complement(19152..19340)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015715224.1"
                     /locus_tag="ES060_RS19460"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="ES060_19460"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MEQLLYASCGFPNVGKGKDLRWGKGLNAVGAFTDL"
     misc_feature    complement(19319..19331)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 20.88"
                     /tool="antismash"
     gene            complement(19570..20143)
                     /gene="yciB"
                     /locus_tag="ES060_RS19465"
                     /old_locus_tag="ES060_19465"
                     /pseudo=""
     CDS             complement(19570..20143)
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0071972 - peptidoglycan L,D-transpeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0018104 - peptidoglycan-protein
                     cross-linking [Evidence IEA]"
                     /codon_start=1
                     /gene="yciB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388217.2"
                     /locus_tag="ES060_RS19465"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="ES060_19465"
                     /product="L,D-transpeptidase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MKLSLFIVAVLMPASLLRSHRRTRKCQYKENGRKHNGCSKNSKNK
                     H"
     gene            complement(20140..21054)
                     /gene="folE2"
                     /locus_tag="ES060_RS19470"
                     /old_locus_tag="ES060_19470"
     CDS             complement(20140..21054)
                     /EC_number="3.5.4.16"
                     /GO_function="GO:0003933 - GTP cyclohydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="folE2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388216.2"
                     /locus_tag="ES060_RS19470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ES060_19470"
                     /product="GTP cyclohydrolase FolE2"
                     /protein_id="WP_130573378.1"
                     /transl_table=11
                     /translation="MNQHTLLPKKTERLQYFGSVSPIKGEKPVEKEKMKDLQNIRKDYF
                     FDIQHVGVANVSHPVTITSAMMPAEQTTAANFTMTCNLPRNQKGINMSRLTELLQVYHQ
                     NGWVLSFSSLQQFTKELAENMDISSATVEVRFPWFFERKSPKLEKAGLMHADIFMSVTY
                     RKDQPFKQRAGISAKVTTLCPCSKEISEYSAHNQRGTVSIWADIHPAASLPSDVKADLL
                     YAAESNASARLHPVLKRPDEKAVTETAYENPRFVEDLVRLIAADLFELEWVSAFEIECR
                     NEESIHLHDAYAKLCFSKEVDRI"
     gene            complement(21171..22376)
                     /gene="nasA"
                     /locus_tag="ES060_RS19475"
                     /old_locus_tag="ES060_19475"
     CDS             complement(21171..22376)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="nasA"
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388215.2"
                     /locus_tag="ES060_RS19475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ES060_19475"
                     /product="nitrate/nitrite transporter"
                     /protein_id="WP_003246358.1"
                     /transl_table=11
                     /translation="MKLSELKTSGHPLTLLCSFLYFDVSFMIWVMLGALGVYISQDFGL
                     SPFEKGLVVAVPILSGSVFRIILGILTDRIGPKKTAVIGMLVTMIPLLWGTFGGRSLTE
                     LYAIGILLGVAGASFAVALPMASRWYPPHLQGLAMGIAGAGNSGTLFATLFGPRLAEQF
                     GWHIVMGIALIPLLIVFILFVSMAKDSPAQPSPQPLKSYLHVFGQKETWFFCLLYSVTF
                     GGFVGLSSFLSIFFVDQYQLSKIHAGDFVTLCVAAGSFFRPVGGLISDRVGGTKVLSVL
                     FVIVALCMAGVSSLPSLSMVIVLLFVGMMGLGMGNGAVFQLVPQRFRKEIGMVTGIVGA
                     AGGIGGFFLPNILGSLKQMTGTYAIGFITFSCIALLAFALVLAAGYYWRKSWSAESSPA
                     DV"
     gene            22555..24870
                     /gene="nasB"
                     /locus_tag="ES060_RS19480"
                     /old_locus_tag="ES060_19480"
     CDS             22555..24870
                     /codon_start=1
                     /gene="nasB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer2_BFD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388214.2"
                     /locus_tag="ES060_RS19480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ES060_19480"
                     /product="assimilatory nitrate reductase electron transfer
                     subunit NasB"
                     /protein_id="WP_130573379.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 3.6e-59, bitscore:
                     194.0, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_BFD (E-value: 9.6e-17, bitscore:
                     54.8, seeds: 211, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKQRLVLAGNGMAGIRCIEEVLKLNRHMFEIVIFGSERHPNYNR
                     ILLSSVLQGEASLDDITLNSKDWYDKHGITLYTGETVIQIDTDQQQVITDRKRTLSYDK
                     LIVATGSSPHILPIPGADKKGVYGFRTIEDCQALMKMAQHFQKAAVIGAGLLGLEAAVG
                     LQHLGMDVSVIHHSAGIMQKQLDQTAARLLQTELEQKGLTFLLEKDTVSISGTTKADRI
                     HFKDGSSLKADLIVMAAGVRPNIELAVSAGIQVNRGIIVNDFMQTSEPNIYAVGECAEH
                     NGTVYGLVAPLYEQGKALASHICGIPCEEYQGSAPSAALKIAGIDVWSAGKIQEDEHTT
                     SIKIYDEQAGVYKKALFADDKLAGVILFGDTRDKQRLLDSLLKQRDISIVKKQIIEPET
                     SGTLFESMPSSETICQCNTVTKGAIEDAVHTKSLTTVEEVKHCTKASGSCGGCKPLVED
                     LLRYMTNSEYTKPAGTLSFCGCTDFTEDDIIAELQRRPFTNPAEVMNQLDWKTKKGCST
                     CVPAIQYYLEMLYPGFVQPEPATEETCILIPQMYGGRTNADQLRTIANIIEAYSISDVS
                     ITHGQRLKLSGIKPADLPNMKKDLKMPVYTNEHRHTLQTIKACTCGQNRSIQQLAAQIE
                     RQLETLPLPAPISISLSCETDCTDAALQDVGAIRTQAGWDIYIGGVRGTHARSGALFCV
                     TENEDSTAGMIKGLIQYYRETAHYLEAVHQWIDRLGIVHIREVLFEEDLRAQLLESLQT
                     DLSLIQNPTVETGAYKKG"
     gene            24877..27009
                     /gene="nasC"
                     /locus_tag="ES060_RS19485"
                     /old_locus_tag="ES060_19485"
     CDS             24877..27009
                     /EC_number="1.7.-.-"
                     /codon_start=1
                     /gene="nasC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1134: flavodoxin"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388213.2"
                     /locus_tag="ES060_RS19485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ES060_19485"
                     /product="assimilatory nitrate reductase catalytic subunit"
                     /protein_id="WP_130573380.1"
                     /transl_table=11
                     /translation="MTERLLRYFRDKQQDVQSEKTYDTQCPFCSMQCKMQLVEQTIVTR
                     KKYTAIGIDNPTTQGRLCMKGMNAHQHALNSSRITRPLLKKNGEFIPVSWEEALNYIKD
                     QVTMIQAEHGHDAMAVYGSASITNEEAYLLGKFARVGLQTKYIDYNGRLCMSAAATAAN
                     QTFGADRGLTNPLSDIPHTRVIILAGTNIAECQPTIMPYFEKAKENGAYIIAIDPRETA
                     TTKIADLHLKIKPGTDAALANGLVKIIIDEQLINEDFIQSRTNGFEELKQHTDSLDLND
                     IAEQTSVPLADIRKAAVKFAKETSGMLFTARGIEQQTDGTAAVKGFLNMVLITGKIGKP
                     YSGYGAITGQGNGQGAREHGQKADQLPGYRSIENEQHRAHVAKVWGIHQDDLPRKGVSA
                     YEMMEKINDGDIKGLFLMCSNPAVSSPNANLVKKALRKLTFFVAIDLFISETAKYADVI
                     LPASSYLEDEGTMTNVEGRVTLREASRPCPGEAKHDWQIICDLASALGKGRYFSYTSAE
                     DIFNELREASRGGIADYSGISYGRLRREGGIHWPCPESDHPGTGRLFTESFAHPDQKAA
                     LSVIPNEPPVPKEKPTADYPLYLTTGRVMSHYLTGVQTRKSAALAARHFESFMEIHPQT
                     AATYNIEDRVLVKIESPRGSITVRSKLSEQIRKDTVFVPIHWADAQNVNDLIGEALDPA
                     CKMPGFKVCAVRIRPI"
     misc_feature    27010..27024
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     strong, score: 24.8"
                     /tool="antismash"
     misc_feature    complement(28185..28194)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.04"
                     /tool="antismash"
ORIGIN
        1 agcctgcgta cttcgcactg cggtcctccg ctgtcatacc gaacgcgtcg tggtgccaga
       61 agcacaggtt cacaagcgca tggtgctcga ccatgacacc cttcggctgt ccggtcgttc
      121 cagacgtata aatcatgtac gccaagttct ccgcggttac agcggtttct ggatttccct
      181 cgtcgttttc atcaagcggc aggcttagaa ttgtgcggct tccgtcgaga agaatgacat
      241 ctcccgtata gctgtccggc actgaaatgc cttcctgttt caagagaagc ttcgcgccgc
      301 tgtcctgtaa aatatactca atccgctgat ccgggtagtc aggatcaatc ggcacaaacg
      361 ccgctccggc tttcaagacg ccgagcaccg cggcggacat ttcaagcgac ggcttcgtga
      421 gaacgccgac gcggtcatcc gggctgatgc cgcagtccat cagaatccgc gcgagacggt
      481 ttgccttcgc attcagctcg ccgtacgtcc aagattggcc gttgtatgtg acagccggac
      541 ggtttttgtg gcgctggaca gtctcttcga atagctgatg aaccgttttg tctgtcggca
      601 caggcagcgc tttacccttc catgcctcaa gaagcgcttg cttttctgtc tcggtgacca
      661 gtgacaggct ggaaagcggc tggttcgggt tcccagtaac agcatctaaa agctccatcc
      721 aatattgctt ccatcgttca atcgtttcct gcttaaacag agctgtattg tattcgagta
      781 cgaatgtaag ccctccgtcg gtttcatcag ccgtcagcgt gaggtcaaac ttggctgttt
      841 tccgttcaaa cggatgcggc tcaagctgaa tccctttcat tgttaaatcc tttatattcg
      901 cattttgcat tgaaaaaact gcatcgaata acggatttct gcttgtgtca cgctgaacct
      961 gaacatttcc gatcaagtcc tcaagtgggt aatcctgcgc atcaaaagcg ctgagtgccg
     1021 tttctttcac ttcgttaaga tagttggcaa acgtcttttc acccttcgga tacgtgcgca
     1081 gcgccaatgt attgacgaac attccgatga cgcggctgac gtccgcttga gatcgtccgg
     1141 ccacaggtga accgacgatg atatcgtctt gcccgctaag ttttgataaa aacgcactgt
     1201 atgaagccag aagcaccatg taaagcgtgg aatccgtttc ttttgcaagc ctgcgcagag
     1261 catcagcttt gcctgcttct aatgaaaatg caatgcggtc tccctcaaat gtttgaacgg
     1321 caggccgact gtaatcagtc ggaagcgtca gcaccggcag ctctccgtcc agctccttca
     1381 gccaatgctc ttcttgcttc ttgtaaagct cagactgaat gaactgctgc tgccacacgg
     1441 cataatcctt atattgaata cggagcggct caagggtttc tccgtcatac agctttgaaa
     1501 gttcttcaat cagcacaccg acagacgcac cgtcagaaat aatgtgatgc atatcgaaca
     1561 gcagcacatg ctcagtgtct gaatgcttga taagccctat tctgaacagt ggaagttggt
     1621 cgattttgaa aggcttaata aactcagaaa cgatccgctc tctctcttct tccggggctt
     1681 cgaaataggc tatctcacac tcagcctctt cccagatccg ctgcaccgtt tctccatctt
     1741 ttatttcaaa cgtggttctc aaggcttcat gacgctgcat taactgctgc atgacgctgt
     1801 taagcctttc aacatcaagc tcacctgtca ggcgcagaac cgccggcatg ttatagctcg
     1861 tttgcgcatc ctcaagctgc tgaagcacgt acatccgttt ttgcggtgaa gaaacaggat
     1921 acgtatcttg tttctctgcc gggctgatac ttgcggctgt ccctttttca gcagacgcag
     1981 tcacctgtgc taagccctca accgtcggtg actggaagag atccttgagt gacagctcaa
     2041 cgcccagttc ctgatgaacc aaggcaagca tcttcatgcc tgctaatgaa tgtccgccaa
     2101 tgtcaaagaa gtggtcataa gcgccgactt gttcagcctg aagcacatgt gcccaaatgt
     2161 ctgcgacttt ttgttccgtt tcattgcgtg gcgcaacata tgaaacacct cttgaaacgt
     2221 tggcatcagg aatcggcagc gctctccggt caatttttcc gttccctgtc agcggcagct
     2281 cgtccatttg gataaacacc gcaggaacca tatatgccgg caagtccttc gcagcatgct
     2341 ctctcatctc ttgtgatgag atgtctcccg ctccgacata gtaagcgcaa agcagtttat
     2401 ctcccgctcc ttgatcaacg gcaagcacaa cactctcctg aacacgatca tgggtttgca
     2461 gctgatgttc gatttctcca agctcgatgc gctgtccgcg aatcttcacc tgatggtcga
     2521 ttcgcccgat aaattcgatg tcgccattcg gcagccatct cgcaaggtct cccgttttat
     2581 acatgcgttc gccggatgta aacggatggg gaacaaattt ctcctcagtc agttctggac
     2641 ggttgtaata gcctttcacg agtccttcgc cgctgacgca aagctctccg gcaatcccgg
     2701 caggctgcac gtgtcccgta cggtcaagaa tgtatacttc cgtattgctg accggttttc
     2761 caatcggaac agacagcgtg tgctcctcca attcatcaac cggatgatac gtcgcgaaaa
     2821 ccgtgctttc agacggtcca tacatgtgaa ggagcttgcc ctttccaacc gtttgcaaag
     2881 cttttctgac atgctcaacc gaagcccgtt ccccgccaaa cataatcttg cgaagcgttg
     2941 acaagcacgc cggattcaag tccacaagca agtggaacaa agcggttgta atcatgagaa
     3001 tgctgatgtt ctcccgttca atgacgcggg acaggcgagc catgtccaaa acggtttcct
     3061 tcggtatcag caccagcttg gctccgttta acaaagagcc aaacatatcg aacataaacg
     3121 cgtcaaacac gtaattggaa agaccgagaa tcgtatcctg ttctgtaatg ctgagataat
     3181 tcgttccctt caccgtgcgg agaatattgg catgtgtcac gatattcccc ttaggtgttc
     3241 cagtcgttcc agaagtatac gtcaggttgg ccattgccgc agaatcaaga ggcagtgcga
     3301 gattgcgcgc atcggcatga tagctctctt cctcatcggc tagcacgata acgcccttaa
     3361 attccgcttc ttccgctaaa gcctttaatt ttctctgagt gagaagcacc tttgctccgc
     3421 tgtcacggaa gaaatgctgc atccgctgaa tcggatgttc cggatcaatc ggaacataag
     3481 ccgaacctga ttttaatact gccaagatcg acacaatcat atccattgac cgctcacata
     3541 agacagccgc tgtcctgcct tcgccagctc caagagaaag aatgccgcgg gctaaacgat
     3601 tggcccgttc attcagctca cgataagtga gtgattcgcc ttcatattga agcgcagtgt
     3661 gatctggcgt attcgccgct tgctcctcaa acagctgaac aattgttttg tctttcggat
     3721 aaggtgttct gcccgggtta aactgctgaa tttgcgaagc agccgcctct tcagaaagaa
     3781 gcttatactc agaaatcggc ttctccggat cagccgcagc atcttcaagc aaacgcgcaa
     3841 aatgcgtaag cagcctgttt gccgtgcttt gtttaaacag cttcgtgctg taatccaaat
     3901 caagctcaat gccttcatcg gtttctctcg cctgcaccgt caaatcaaat ttggcaatct
     3961 tgaaattggt ctcatgaaca gacaaggaca gatcgccgac agccggaatg ccctctgtcg
     4021 cgttttgaag gctgaacatc gtgtcaaaca gcggatgcct gctaacatca cgcgggatgt
     4081 tcaaatcttc aacaagccac tcaaacggat agtcctgatg agaaaaggca ttcagcacct
     4141 gtttacgaac acgcgagatc aattgggtaa acgtctcatc ctgcttgacc tcactgcgaa
     4201 tcgcaagcgt attgacgaac atcccgacaa tgccctctgt atcggaatga tttctgccgg
     4261 ctgacggtgt cccgacaatg atgtcatcct gtcccgtata ctttgacaaa agcgtatagt
     4321 aagcggacag catcaccata tataaagtgg cgccgttttg ttcagccaaa cgattgaggc
     4381 gatcctttac ccccgcatcc agcttgattg acacccgatc cccttcaaag ctttgaacag
     4441 gcggtcttgg gtaatcggac agaagttgaa gcaccgggag ctcgcctgca aagacttcct
     4501 tccaataagc ctggtccttc ttgtaccctt cagcagcctg tctgctttgc catacagcgt
     4561 agtccttata ctggagacga agttcaggaa gctgttcgcc tttataaatg cgtgctaact
     4621 cctccagcat aatgccaatg gatacaccat cagaaatcaa atggtgcatg tcaaacagca
     4681 gcatatgacg gttctcttca agccccagca aaccgattct gaatagcgga gctttcgcca
     4741 aatcaaattt ccgaacgaat gaagccataa ttgcctcatc tgagcggccg cctctttcaa
     4801 tcatttcgat gttgaaatca acgctatcgt gaatgttctg tctcggcgtg ctgttttcaa
     4861 gaacaaatga tgttctcaat gactcgtggc gtcggattaa cccctgaaat gcgcgctcca
     4921 gcttttgaat atctaaaggc ccttctaata ttgctgctgc cggcatgttg tagccgactc
     4981 ccgcatcctc gaactggctg acgatatatg ttcgctgctg tgccagggaa agcgggtaat
     5041 gttcctgttt ttcagcaggt tcaatcaccg aaaatgcccg gctttctctg tgatcagcct
     5101 cctctgcaag agccgcaatc gtcggatgct caaacaaata ttgaagcgga atctcgacgc
     5161 ctgtttgctt atgaatcttt gttaaaaggg tcatggcttt caatgaatgc ccgccagttt
     5221 caaagaaatt gtcaaagatc cccgccttct caacattcag tacgtcctgc caaatggctg
     5281 cgattgcttt ttcagtctca tttcgcggcg ctgtataggc agtgccgctg acagccttca
     5341 cctctagtgc aaacagcttg cggcggtcga ctttgccgct tggcgtaagc ggaatttctg
     5401 tcacttctgt aaagtaagcc ggcaccatat agtcaggaag ctgtctggcc gcatgcgccc
     5461 tcaagccggc tggcgcaaat tcgctttcag gcttctgcac aacatatgcg caaacctcaa
     5521 gatttccctg ttcgtcaggg cgtgccaaaa caacggcttt tgcaacgtct ggcgcctgct
     5581 gaatcacggc ttcaatttcc ccaagctcaa tccggtatcc gcggactttg acctggtcat
     5641 cctctctgcc taaatattcg attgttccat ctggaagcca gcgcaccaca tccccggtcc
     5701 ggtacatgcg atcgcccggc acgaatggat cttgtaaaaa cttctcttcc gttaattcag
     5761 gcaaatgcaa atagcctcgg cccacaccgg ctcccgcgat ataaagctcg cccgccacgc
     5821 cttcaggctg cagccggcct ttttgatcca aaatatataa gcggttattc cccagcgctt
     5881 tcccgatcgg cacatacgct gattgaactg caatctcagg gataaccgga tgaacagacg
     5941 cgtcaacgca cgtttcagtc ggcccataca cattggtcaa acgcggcgct gtgccggctt
     6001 ctttaaacag cttcagcagc ttgtccgcaa caacagatga caggccttct cctccgatca
     6061 gcatgtgttt cagttttaga ccttcaaaat cgcctgctgc taccagcatt tgcaaatgag
     6121 caggtgttcc atctgtcgcc tcaatgctgt ttctccgata atatgcagta agggcggccc
     6181 cgttcgtcac tgttttcttc ggtacgatat aaagggtttg tcccaaaaga agcgacgcga
     6241 agatctgctt cactgacgca tcgaagtgga acggcgcaag caatgccatc cgcagggttt
     6301 ggctgccgct ttgataaatc gtctgctgca gagattcaac caaatgatga acttggcgat
     6361 gctcgatcat aacgcctttc ggacgtccgg ttgttcccga tgtgtaaata atgtaggcaa
     6421 ggttccgtgc gttcacatct gcattcaggc tttcttctgc accttctgca attgcctgat
     6481 ctaagtcaat cagctcagca tcggcttcag gcgccgcaac cttcgattca gtcaggatga
     6541 agtccgcccc gcagtcctcc aaaatatatt gaatgcgctc agcaggaaaa cccggatcaa
     6601 tcggcacata ggctccgccg gcttttaaaa tccccatgat agctgtaatc atccgttcag
     6661 agcgttcaat caaaaccgcg acaggactgt ccgggccaac ccctttctgt ttcagcacat
     6721 tggcgatgcg tgccgattgt tcatgtaacg ttcgatagga caatgtacga tcttcaaata
     6781 caaccgccgg atgatctgaa agctgctcag ccttttcttg gaacagttcc gggatcgtca
     6841 tgtccttacg gtagctcaca gatttaccgc cggccctcgc aagcagcttc tctttctccg
     6901 catcagaaat catcgttaat tcatcaattg tatgttctgg atgcgttaac gcgttctcca
     6961 gcattgtaat catgcgctca caaatcatgt tgatttcttc acgtgaaaat aaatcagtgc
     7021 ggtaatcaaa atctatggtg agtttcccag tatcccatcg atccttcaca tggatcgaga
     7081 catcatttaa tccgctgccg ctgaaaatcg gctcagtcaa aaaggcaagg tcctcttctt
     7141 tttgccactg catcacctga tattcaagag aaacagtaaa cagcttggtc agagagctct
     7201 ttgtttcacg caaatcgttg atcaggagat tatacgggta cttttggtgg cggagtgtct
     7261 tcatgagatc cttcatccgg tctttgacaa attctaaaaa cgcctgcccg ccgtcaatgt
     7321 ttgtccgaag cggaaccgta gaaacaaaca tgccaagcat ctgcttctct ttcgcatttg
     7381 tccggttgcc cataaaggtt cccgtcacaa catcattctg gccgctgacc ctgtacaagt
     7441 aggcggcgag caacgattga aataccgaaa gaacactgac tttattcgcc tcacaaaatg
     7501 acagaatctg ctgatgaagc gcttcaggca catctttaga gaacctctca gcatctaaac
     7561 ttcctcctgc ggaagcattc cgtttcaggg aaacaagttc aggcaccgat tcaaattgtt
     7621 tgttccaaaa cgccttgtcc ttttcaaacc gcttcgattg agcatagtcc tgttcagata
     7681 aaacatgatc gataaatgaa tgcgagattc cttcttttgt ctctgagccg ctggctaatt
     7741 ctaaataaat gtgcatgatc gcattcccga gaatattcat ggagatacca tcagaaatca
     7801 cgtgatgaac atttgcgtaa aaccacactt cattttcctt tatggtgaac aaggaaaaac
     7861 gaaataaatc acaatcgtac agcggcaacg gtttcttcgt ttcctcccgg ctccattgtg
     7921 aaataaactc tatcgcattc ggatcttcag tagtgtcagt atgttttata tcaacaggcc
     7981 gatactcgct aatatattga acaggctccc cgttttcatc tagccgcaac cgaaggcgca
     8041 tggcttcatt tctgcgaata aactcttgaa tcgcctgctc aacaagtaca taatcaatcg
     8101 catcagctga aaccagctta ccaatccccg caagatttga aatgctcgtg tgaggataaa
     8161 atttttctgt ataccaaatt cgtttttgtg catccgttaa agggtaaaaa gttatttcca
     8221 tattgtcata cctcccctaa tctttataag cagtgaacat gtgcaacgca ttttctcttt
     8281 cttatccata tcagctttta attcttatga actaacagcc gaaatagccc aaagtactac
     8341 acttaaaaag cagagcttcc aaacaaaaaa acagattgcc gctattaaaa cgggcagccg
     8401 tcagtcagca ttgcggcgtt taacataagt ggataaagac cgcaagatcc cctatcctaa
     8461 taggaaacaa ttttggctat ttattcattg ttttcaatat tttttatctt actaccgttc
     8521 actttaaatg aaaaaaatgt ttttatcacc gaaaaatggg tgaaaagttt catgcgggat
     8581 gccgaaagat tccagtttat ttacagggat atttttgcgg gatgccgcaa tcatttccac
     8641 taaacattat ttacagaaaa ataaaaattt ttaaaccaaa ctgctgcgtt caatcttttt
     8701 ttattgctga atgcaattta caatctttac atgactatgt gtaccgcgca aaaaccgaaa
     8761 aaaaggcaaa aaaaaagaca cccttgcgaa gagcgtctta taacgattct ttcatgacat
     8821 ttttgtcgat atcaatcaat tccatatagc ctttccccca ctcatacatg gcttcaagaa
     8881 taggcatgag gctttctccg tgcggggtca gagaatattc aaccttcggc gggacgaccg
     8941 gatacacttc cctgtgaaca atcatatcct gctcaagctc tctcagctga ttcacgagga
     9001 tcttctgcgt aatatcagga atcaatgttt ttaattcatt gaaccgcttt gtgccttctt
     9061 ttcctaaatg ccataaaatg agcatcttcc atttaccgcc aatcactgca agcgttaatt
     9121 ccttctcaca attaaacctt ttgtcgtcca tccggctcaa tagaatcccc ccttagtaac
     9181 ctttttgtat gttagatacg tatcatcact tacttacttt ttttgcagac tcttttttca
     9241 ttatactcac tcataaaatc aagcgaaaga aatctgattg tctctcctca cagtatcctc
     9301 caagtaactt gttgacttca aagtgcctac ttctaatcaa ataagagaac ctatagaatg
     9361 aaaaataatt cgaaaaaggg agtggatcaa caatggaatt acagcttgca ttagacctcg
     9421 tcaacatccc ggaagccatt gagctcgtca aagaggtaga acaatacatc gacgtagttg
     9481 aaatcggaac accggtcgtc attaatgaag gcctaagagc cgttaaagaa ataaaagaag
     9541 catttcctca attgaaggtt cttgcagacc tgaaaatcat ggatgccgga ggctacgaaa
     9601 ttatgaaagc gtcggaagca ggcgctgaca tcatcaccgt tttaggggct acagacgacg
     9661 caacgattaa aggcgcagta gaagaagcca aaaaacaaaa gaagaaaatc ttagtggaca
     9721 tgattaacgt gaaagatatc gaatcccgtg cgaaagaaat tgacgcactc ggcgttgact
     9781 acatctgcgt ccacactggc tatgatcttc aagcagaggg caaaaactct ttcgaagaat
     9841 taacgacaat caaaaatacc gtaaaaaacg caaaaaccgc aatcgcgggc ggcatcaaac
     9901 ttgatacact gccagaagtg atcaagcaaa accctgacct tatcattgtt gggggcggaa
     9961 ttacaagcgc agctgataag gcggaaacag cttcaaaaat gaagcagctg attgtccaag
    10021 gataactccg atgaaaacga ctgaatacgt agcggaaatt ctcaatgagt tacaccgttc
    10081 agcagcttat attgctaatg aagaagctga ccagcttgcc gatcacattc tttcatccca
    10141 ccaaattttc accgcgggtg cggggcggtc tggcctgatg gcaaaatcct tcgcgatgag
    10201 actgatgcac atgggcttca acgcccatat tgtaggtgag attctcactc cgccgctcgc
    10261 caaaggagat ctagttatta tcggctcagg atcaggcgag acaaaaagct tgattcatac
    10321 cgcagcaaaa gcaaaaagct tacacggaat tgttgccgct ttaaccatca atccggaatc
    10381 aagcattgga aaacaagcgg acctcatcat cagaatgcct ggttctccta aagaccagtc
    10441 aaacggaagc tataaaacca ttcagccaat gggatcatta tttgaacaaa ctttgctgct
    10501 attctatgat gcagtgattt taaaactcat ggagaaaaaa ggactcgatt ctgaaactat
    10561 gttcactcac cacgcaaacc ttgaatagca tcacacaacc ggcctgaaga tcaggccggt
    10621 tttatttttt ctaaaataaa actttaaacc caaaaacccg ataagtaata tgacctacaa
    10681 atcataaagg gaggaattat gttgataaaa cgacttgaga tgaagctagg aactaaaatt
    10741 ctttgcctcg ttttcgtggt gattcttttg ttttcggcat cagttggcac tgtgatgctt
    10801 aaggaaatta cagaaagcat gaaacaaatg gcaactgaaa aagcgaaagg tgatctcgct
    10861 ttaagcagca cttatattga tgatgtcatg tcaggcgact ggcaggtgaa aaacaataag
    10921 ctctataaag ggcaaacaca aatcaatgga aatgaagata ttgttgatct gcttggcgaa
    10981 aaaacaggtg ataccattac cattttccaa ggcgatactc gtgttgcaac caatgtcatg
    11041 aaaaatggcg aaagagctgt cggcacccag gcttcttctg aagttattgc cgctgtttta
    11101 aagaaaggaa agcgttttta cggacaagca gatgtagcag gttcttctta tcagactgca
    11161 tacatgccgt taaaagatca aaatgggaac atcatcggca tgctgtatac cggagctaat
    11221 caaagtattt taacatcact tacacaatca cttttcactc aattcgctat cgttcttgtt
    11281 atcgtgatta tggtatcagt catccttgtc ttggttttca ccagaaaaat caacaagcgg
    11341 ctgaacgctt taaaaagcgc ctttgaaagt gccggaaacg gagatatgac aatagaggtg
    11401 tcagacaaaa ccggtgacga gctatcagaa ctaagcgtct attataataa gatgagaatg
    11461 aagctgaacg ataccataca aaccgtacaa caatcagccc ttcagcttgc gtcagcctct
    11521 cagcagctct cagccggagc agaggaaaca aatcaagctt cagaaaagat cacagaagct
    11581 gtacagcaga ttgcaaatgg agcccaagat cagatcaccc gaattgaaaa cagtgaaagc
    11641 tcattaaaac aagcttcagc agacatccgg gatatttctg caaatactgc cgctatcgct
    11701 gacaaagggc agctcgcgca atcaaaagca gacattgggc aaaaggaaat tgcaaatgta
    11761 caggcgcaaa tggatgcgat tcaccagtca attcagaaaa gcggagaaat catacaccag
    11821 ttagacggcc gctctaaaca aattgagcaa attttatcgg tcatcaccca aattgccgat
    11881 cagacaaacc tgcttgcgct gaatgcagca attgaagctg ccagagccgg tgaacaagga
    11941 aaaggctttg ctgttgttgc tgatgaagta cgtaaattag cggaagagtc tcaacagtct
    12001 gcgggacaga tttcaaaact gatcatagaa atacaaaagg atatgaaccg gtctgcaaga
    12061 tctgttgagc atgtgaaaac agaagctgca gaaggagtca ccatgatcca gcgcaccaga
    12121 gatgcattta aggaaattgc agctgcaaca ggtgaaatca gtgccgagat tagtgattta
    12181 tcagcatctg taacaaacat ttcagccagt gcacatcaaa taaatgattc ctttgcagcc
    12241 aatacggccg acattaaaga atctactaaa aatacccggc aagcggctgc attaacagag
    12301 gagcaatttg ctgcaatgga agagattacc gcagcttctg aaacgctgtc tcaattagct
    12361 gaggagctta ccggtatcat aagccaattt aaaatgatta atcaagccga aaacggctga
    12421 tgacttacta tcattattgt aaattggcaa tcgtattttg ctgaaaacaa atatttcgac
    12481 ctgctaaaat tacgattttt gcaataaact gagcgtaaaa cataaaattt aaacctttac
    12541 accaaatgct ttctggatta ctcttgtgtc agttttaaaa gcgggaggtg aacatcacga
    12601 cggacatcat aaaaacaata cttctcgtca tcgtcataat agcagctgca gctgtcggcc
    12661 tgataaaagg agactttttc tcagctgatc aaaaaacgtc tcaaacgaaa gaatatgatg
    12721 aaacaatctc cttcccttct gaccgttatc ccgaaacggc caagcatatt aaggatgcga
    12781 taaatgaggg gcactcagag gtgtgcacta tcgacagaga cggagctgag gaacgccgcg
    12841 agcaatcatt aaaggacgta ccttccaaaa aggggtatga cagagatgaa tggccaatgg
    12901 ccatgtgcaa agaaggcggt gagggagctt ctgtagaata catttctccc gctgacaacc
    12961 gcggagcagg ctcttgggtc gggcatcagc ttaccgatta cccagacggc acaaaggttt
    13021 tattcacaat tcagtaaaca gtacatagag gaggaacagc acattgatca aatcatggaa
    13081 gccgcaagaa ctttcgattt catatcatca atttactgta tttcaaaagg attctacacc
    13141 tcctgtaatg gattggactg acgaagcgat tgaaaaagga tatgcagcgg cagacggagc
    13201 catttccttt gaggcacagc gaaatacaaa ggcctttatt cttttgcgcc tgaacagttc
    13261 agaaacagta aactcctacg aaacaaaagt gactgttcct tttcatgtca cagaaaacgg
    13321 aattcatatt gaaagcatca tgtctaaaag actgtccttt gatctgccta aaggagacta
    13381 tcaattgaca tgctggactg tgccggctga aatgtcagat ttgcacgccg acacttatat
    13441 tattgatgct gtttctgtgt aatgaaaaac ccctgagaga ataactctca gggactcttt
    13501 ataaactttc tccgtttgtc ttgatgacat cttgatacca ataaaagctt tttttcttca
    13561 agcgttttaa atcgtatgtg cttacttcat cacgattgac atatacaaat ccgtatcttt
    13621 tttggtagcc gttcagccag cttaacagat cagtaaacga ccagctgcaa tagccgatta
    13681 aatcgacacc gtcactgatg gcttgtctgc attgctcaag atgcgaacgc aaataatcaa
    13741 ttcgataatc atcctgtaca gtgccgtcct caactttatc aaattcaccc aaaccgttct
    13801 ctgttataaa cactggaagc tgatagcggc ttgtaattcg gcgaagaccg atacgcagcc
    13861 caattgggtc aattgtccaa tcccagttgc tcgttgtcag atgcggattt tttttcgttt
    13921 tgaacactcc gggtatcccc gtctcctgat tggttccctt ttggcctgtc gtattcattt
    13981 tcccttcaga cacaccatca agcggatttc gttcataggt gatcgtctga taataattga
    14041 cacctacaaa atcaggcttc cctttggcaa gcagctccat atctcctgct tcgattttcg
    14101 gcgcccatcc ctgtttttcc aagtagcgga atggaatttg cgggtaggtt ccccagcaat
    14161 acatgtcaag ccaccaattg ttcataaatt cttcggcgtt ttcaaatgcc agtatatcct
    14221 ctggatggct tgataaaggg taagccggag aataagcaaa gctaggacct attttgcctt
    14281 caggcacata ttctctaaat gattcgatgg cttttgcatt agccagaaac gcaatatgat
    14341 ttgcttcgta aaatcgtttt ctgtctttca ctccaggcgg atgcatggct gtaataaatc
    14401 catgattaaa attgtagttc tgttcattta acgtaaccca atatttcacc ctgtctccaa
    14461 aacgtttata aagagtaata cagtagtgat taaaatcctc tatgatgttt ctggattcaa
    14521 acccgccgta ttcgtccata agcgcttgag gcaaatccca gtgatataaa gtcagaaccg
    14581 gctcgatgtg atgagaaagc aattcatcaa tcagactatc gtaaaacgct agacctgctt
    14641 cattgatctc tccttttcct tttggaaaaa cccgtggcca gctgacggaa aatcgatatg
    14701 cttttaaccc catctcagcc atcagagcga catcttcttt aaatcggtga taatggtcaa
    14761 ccgcaatctc gccatcggtt cctttaaacg ttttgcccgg tattttcgta aacacatccc
    14821 aaacagaagg gcctttgcca tcttcattcc aagcgccttc aatctggtac gctgcagaag
    14881 cagagcccca caaaaaatgt ttcggaaaag attctggatg ctggtggatc atagtgttta
    14941 tcactcctga attattgata aacctatcat aggctatgaa acgcgtttca tatcaactcg
    15001 atgttagtcg cggaacagct cagctaatat tgcctacctg taaataacgc aaagcaccca
    15061 attcccattg gatgctttcc atcttaatgt cttttttcaa atttatgcgg atgaggatgg
    15121 tgctttggaa caaagccgtt ttgtttcatc atttcaaagt gtttgtccaa gtgatttttg
    15181 atgtgttctc ctctttcttt aggcaggata ccgtattgta catactttga gatcacgtct
    15241 ttgcgctttt taagaatctc tgcttccagt tgttcaatct ctttcttttg ctgatctgtc
    15301 agtgtaacat ttgcgggagg ctgctgctgt ttttcagcgg cctcagctgt accggtcaga
    15361 gaaatgacag ccgctgcaat gaacattgtg atgatgttga tggttattcg tttcatccag
    15421 tttattcctc caatcctatt tttcatatgt tttgctgcct tgtatttttt atgcataaaa
    15481 ataaaaagag cgaaccatta ttcgctcttt ctaatctctt cgtcagcatt aagttcttct
    15541 tcacctggtg tcgcataagt gacatatgtt cccgcgatta aatcatgcag ggtccgtttg
    15601 tcttctcgta cggcaatcag aatcaggctg gcgatcaagc cgagtccgaa ggttataacg
    15661 taaaccaggc cggctacaat aacccgtaaa aacattgtta acagactgac ctgtgatccg
    15721 tcttttttta cgattctgat tccgcagatc ctttttccga taagataacc gcgccaaaac
    15781 accggcagca aaatagaata cagcagaaca accaaactga tgaacatgct gtcgtttggg
    15841 tcttttcctg taatcagcca atagatcagc aaaagcggca cggagactat aatatagtct
    15901 aacaatgcag ctccaagtct gatccaaaat ccggctggtt tgtaaatatt catttgactc
    15961 cccattatgg tttaaatgtt tccattttct ttctcatcgg atatatcata tgtcttaggg
    16021 gcatcagcaa gacttaaatt tattctgaag atcgatttca tgcttctgac catttcttac
    16081 ggtattggca tagaggaata acggatctgc tgcatccttc acgtccacat gtgtttcctt
    16141 ggtacgtcgg gcattcatcc ttggacaact cctttgttca tcaccaattc ccttcatagc
    16201 cgctattaaa cacccactat gccttttgta tacacaattc gaactttttg aaaacgcgat
    16261 caacatattg caacccctta tgttcaatgc tatcttttta gttgattaac agattggggg
    16321 aaatataggt gaaatcattc aagcaatcca aagccgttat attcagtttc acaatggctt
    16381 tctttcttat attggcagcc tgttccggca aaaatgaagc cgattccaag gatacaggct
    16441 gggagcaaat caaggacaaa gggaaaatcg tagtcgctac atcaggtacg ctttatccca
    16501 cttcttatca tgataccgac tctggctccg ataagctgac gggctacgag gttgaagtcg
    16561 ttcgtgaagc ggcaaaacgc ctgggactga aggttgagtt caaggagatg ggcattgacg
    16621 ggatgctgac agcggtgaac agcggacagg ttgacgcagc cgcgaatgac atcgatgtga
    16681 cgaaggaccg cgagaagaag ttcgcatttt ctactccata taaatattca tacggtacgg
    16741 caattgtccg aaaagacgat ttatcaggga ttaaaacgct taaggattta aaagggaaga
    16801 aagcggctgg cgcggctacg accgtctaca tggatgtcgc gagaaaatac ggcgccaaag
    16861 aagtgattta tgataatgcg acgaatgagc aatatttaaa agatgttgcc aacggacgca
    16921 ctgacgtcat tttaaacgac tattacctgc agacacttgc gctcgcggca ttcccggatc
    16981 tcaacattac aattcatcct gacatcaagt acatgccgaa caaacaggcc cttgtcatga
    17041 aaaaaagcaa tgaagcactt cagaaaaaga tgaacgaagc attgaaagag atgagcaagg
    17101 atggctcttt gactaaactg tcgaaacaat tcttcaataa agcagatgta tcaaaaaaaa
    17161 ttgatgccga cgttcaggac gttgatttat aatcggacgc catgatcaat agcattcaat
    17221 gggaatatat tttcaacacg aagctggcta ttgaatcgtt cccttatgtc ataaaaggca
    17281 ttgggtatac actgctcatc tcttttgtaa gcatgtttgc aggaactgtg atcggcctgt
    17341 tcatatcact cgccagaatg tctaagcttg ctttgttaag atggccggcg aagctctata
    17401 tctcatttat gcggggcgtt ccgattttag tgattttgtt tatcctttat ttcgggtttc
    17461 cttatatcgg cattcaattt tccgcggtca cggctgcttt aatcggcttt agcctaaaca
    17521 gcgccgccta cattgcggaa attaaccgtt cagccatttc atccgtcgaa aaaggacagt
    17581 gggaagccgc atcctcgctg ggtctttcct attggcagac gatgaggggc atcattttgc
    17641 cgcaatcgat acgtattgcg ctgcctccgc ttgccaatgt gttgctcgac ttaatcaagg
    17701 cgtcatctct cgctgcgatg attacagtgc cggaattgct ccagcatgcg aaaatcatcg
    17761 ggggcagaga gtttgattat atgaccatgt atattctgac cgctctcatt tattgggcca
    17821 tctgctccat tgccgcggtc tttcagaata tccttgagaa aaaatacgct cattatgttt
    17881 aaacaaacgt ttcattaaaa aaagccgctc cccatgggac ggcttttttt ctattgattc
    17941 agcttccatt taaacgggtc ctcaaacagc gaccagtcgg aatcaaattc atattcagtc
    18001 agcaggcatt gatcaagctc tttcgtgatc gtttcttcat ccaggtcagt tccgataaaa
    18061 actagctgcg ttaggcggtc gccgaactcc gggtcccact cctccaggat ttccggctcc
    18121 tgctgtttga cttgctcctg ctcaagcttc ggcagcgccg ccacccaata agatacaggc
    18181 tcaatcgtaa ccgacggacc tgcttgcgac atcagcaaag cgaggttgtt atgagatgcg
    18241 caccagacga ttcctttggc acgaaccacg ttctttggca tttgatctat ccattgataa
    18301 aaccgtgtag aatgaaacgg caaacgtctc ttatatacaa atgaagagat accgtattct
    18361 tctgtttccg gggtgtgttc cgcatggcct gccgtcagct cttgaatcca gccggccgat
    18421 ccgctcgctt cctcgaagtt aaataaccct gtatgcaaaa tctcctgcgg ttttacattt
    18481 cctttgacgg aacgaatgaa cttggctctt ggctgcagtt tacgaagaac tttttcaagc
    18541 tgttcgagct cttgctcgct gaccaaatca catttattta agatcagtac atcgcaaaac
    18601 tcaatttgat cgatcaagag gtcggcgatt tctctttcat cctcttcccc caatgcttct
    18661 ttgcggtcca gaaggctttc gcctgactga taatcatgcc aaaaacggtt ggcatcaacc
    18721 actgtcacca tcgtatccag ctgacagaat tttgtaagat cgattcccat ctcttcatcg
    18781 atataagaga aagtctgggc caccgggatc ggttcactga ttcctgtcga ttcgatgacg
    18841 atataatcaa accgtccgtc ttttgccagc ttctcaactt caattaataa gtcttcgcga
    18901 agcgtgcagc aaatgcagcc gtttgacatt tccacaagct tttcatctgt tctggaaagg
    18961 cccccttcct gcttaaccaa gcccgcgtca atgttcacct cgctcatatc gtttacgata
    19021 accgctattt tcaagccttc gcgattttgc agaatgctgt tcagcaatgt tgtttttccc
    19081 gcacctagat aaccgctcag tacggtaacc ggaatttttt tcataataac gcctccatta
    19141 aaatagaatg attacgattt aaattgtata ctttgccgta tgtacaatgg tgtagagcag
    19201 cttttcgcgc tcatttcccg ctgccgcccg atttataaat cagtaaaggc tccaaccgcg
    19261 tttaatcctt ttccccatcg caaatccttg cccttgccga cattcggaaa accgcagctt
    19321 gcataaagca attgctccac ttgcgttgct gaaccgatgg aaagcgcaaa tatctcatca
    19381 gaaagtagct tgggtttcgt ttccagcatt caagaggccc ttcacaagga tcaatgacag
    19441 caagatcctt aatcgatgcc tttccgcttt tcacagatgc acagacaatg ataagccatt
    19501 tatcataaaa cgtaattgtt acgatttaaa ttgtatggcc ttttttcctt tttgtcaacg
    19561 gttttcaatt cagctgatca ccacttttgt atgttcaggg atattttcat atatccattt
    19621 cgcatctgga atggtcagcc tgatacaacc gtgagatgct ttcgttccta gtttttctgc
    19681 ttccgttttg atgacttttt gatccttagt cattggcaca ctatgaaata gaaattcacc
    19741 gtgatttttc catgataccc agtattctgc gccttcctgg tatccttcgg aaaaaaacca
    19801 ttctccccgt tcaggctcta cataaaaggt gccctttggc gtagcatcat cttttgtttg
    19861 atcaagacca gaagagatca tcattgtata gatggtgttg cttccttcct tgatgtaagc
    19921 cttctgctcc ttcacattca catcaatcca gacatgcttc tgtttaatat ccgggtattc
    19981 tccgcccgaa ggcttcgtcc aatcaatgct tgtttttgct gtttttcgaa catccgttat
    20041 gttttcgacc gttttctttg tattgacact tgcgtgttct tctgtgtgat cggagcaggc
    20101 tggctggcat aagaactgca acaatgaata atgagagttt catattctat ccacttcctt
    20161 cgaaaaacac agcttcgcat aggcatcgtg gagatggatc gattcttcat ttcggcattc
    20221 aatctcaaag gctgacaccc attcaagctc aaacaaatcc gcagcaatca gccggacgag
    20281 atcctcaaca aatctcgggt tttcataggc cgtttctgtc acggcttttt catcaggccg
    20341 cttcaatacc ggatgcagtc tcgcagaagc atttgattct gcggcgtaaa gcaaatcagc
    20401 tttaacatca cttggcagcg atgcggccgg gtgaatatcc gcccaaatgc tgaccgttcc
    20461 cctctgatta tgggcgctgt attcgctgat ttccttggag caagggcaca gagtcgttac
    20521 ttttgctgag atgccggcac gctgtttaaa cggctgatct ttgcgatagg tgacagacat
    20581 gaatatatca gcatgcatca aacccgcttt ctcaagcttc gggcttttcc gttcgaaaaa
    20641 ccacggaaac ctcacttcaa ctgtggcaga tgatatgtcc atgttttctg caagctcttt
    20701 cgtaaattgc tgaagagagg aaaatgagag aacccagcca ttttgatgat agacttgcag
    20761 cagctctgtt aaccggctca tgttaatccc cttctgattt ctcggcaaat tacaagtcat
    20821 tgtaaagttc gcagccgttg tttgctcggc aggcatcatg gcagaagtga ttgtgactgg
    20881 atgggacaca ttagcgacac ctacatgctg aatgtcaaaa aaataatcct tcctgatatt
    20941 ttgcaggtcc ttcattttct ctttttccac tggtttctcg cctttgatcg gactgaccga
    21001 tccaaagtat tgaagacgct ccgttttttt cgggagcagc gtatgttgat tcattcagaa
    21061 aactcctctc gctaacaaat cgtaataatt actatttatt ttgatcggtt cactgttgaa
    21121 aatcaagaga aaataaaaaa gacacgcaca aacgcgtgtc cgtcaaaaac ctacacatcc
    21181 gccgggctgc tttccgcgct ccagcttttc cgccagtaat agcctgcggc aagcacaagt
    21241 gcaaacgcca gcagcgcgat acaggaaaac gtgataaaac cgatagcata tgtgcctgtc
    21301 atctgtttga gagatcctaa gatgttcggc aggaaaaaac ctccgattcc tccggccgca
    21361 ccgacgattc ccgtcaccat gccaatttct ttgcgaaaac gctgcggcac gagctggaat
    21421 actgcgccgt ttcccattcc gagccccatc attccgacaa acaatagaac aataaccatt
    21481 gagagagatg gcaggctgct gactccggcc atacacagtg ccacgatgac aaacagtaca
    21541 gaaagaactt tcgtgccgcc gacacgatcc gaaatcaagc ccccgacagg ccggaaaaag
    21601 ctccccgccg ccacacataa tgtaacgaag tcccctgcgt gaatttttga cagctggtat
    21661 tgatcaacaa agaaaataga taaaaagctt gagagcccga caaatccgcc aaatgtgacg
    21721 ctgtacagca ggcagaaaaa ccatgtttcc ttttgcccga acacatgcag atagcttttg
    21781 agcggctggg gagacggctg tgcaggagaa tcctttgcca tggatacaaa aagaataaag
    21841 acgatcaata atggaattag cgcaattccc atgacaatgt gccagccgaa ctgctctgcc
    21901 agacgagggc caaacagggt tgcaaacaac gtgccgctgt tccccgctcc ggcaatcccc
    21961 atcgcaagcc cctgcaaatg aggcggatac catcggctgg ccataggcag cgctacagca
    22021 aagcttgccc ccgccacgcc aagcagaatc ccgatggcat acagctcagt cagggaacgg
    22081 ccgccgaatg tcccccaaag cagcggaatc atcgtcacca gcatcccgat cactgccgtt
    22141 tttttcggtc cgattctgtc cgttaaaata ccaagaatga tacgaaacac tgatccagat
    22201 aaaatcggca cagctacgac aagccctttc tcaaaaggag acaggccaaa atcctgagaa
    22261 atataaacac ccagcgcccc aagcataacc catatcataa aactgacatc aaaatataaa
    22321 aaggaacaga gcaaagtgag tggatgaccg ctagttttca gttccgacag cttcataaga
    22381 ttcccctttc tagaccctca ttattttaca ttttctgaat caaggatata ggacccttat
    22441 tttctggaaa agacatgtgt aagtttttgt gacacgttta atgcgttaac agtgcattgt
    22501 gacataattt ttaataggag aaaacttacg agcttcgcca aaggaggtct gataatgaag
    22561 aaacaaagat tggtgttagc gggaaacggc atggccggaa ttcgctgtat tgaagaagtt
    22621 ttaaagctga atcgccacat gtttgagatt gtcattttcg gaagcgagcg gcatcccaat
    22681 tacaatcgca ttctcttatc ctctgtattg cagggtgaag cgtcactcga tgatattaca
    22741 ctgaacagca aggattggta cgacaagcac gggatcacgc tttacacagg cgaaacggtt
    22801 attcaaattg atacagatca gcagcaggtc atcacagatc ggaaacgcac tctgtcgtat
    22861 gacaaattaa tagtggcaac aggctcctcc cctcatattc tccctatccc cggggcagac
    22921 aaaaaaggtg tctatggatt tcggacaata gaagactgcc aagcgctgat gaagatggcc
    22981 cagcactttc aaaaggctgc ggtaatcgga gccggcttat taggactgga agctgcagtc
    23041 ggtttacagc atctcggtat ggatgtcagc gtcattcacc actccgccgg cattatgcaa
    23101 aaacagctcg atcaaacagc ggcgcggctg ctgcaaacag agctggaaca aaaaggccta
    23161 acctttcttt tggagaaaga caccgtctcc atttccggca ccacgaaggc agaccgaatc
    23221 cattttaaag atggctcttc attaaaagca gacttgattg tgatggcggc cggcgtcaga
    23281 ccgaatattg aattggctgt atccgctgga atccaagtga accgcgggat catcgtgaat
    23341 gactttatgc agacaagcga accgaatatc tacgccgttg gtgaatgcgc tgagcataac
    23401 ggaacggtgt acggattggt ggctccgctt tatgagcagg gaaaagcgct cgccagtcat
    23461 atttgcggca ttccatgtga ggaatatcaa ggctcagcac catctgcggc gttaaaaata
    23521 gctggaatcg atgtgtggtc agcaggaaag atccaagagg atgaacacac gacgagcatc
    23581 aaaatctacg acgaacaagc aggagtttat aaaaaagcgc tttttgcaga tgacaaactg
    23641 gccggcgtta ttttattcgg agacacccgt gacaagcagc ggcttctcga cagcctgctt
    23701 aaacaacgag acatctccat tgtcaaaaag cagatcatcg aaccggagac aagcggcact
    23761 ttatttgaat ccatgccttc cagtgaaacg atttgccaat gcaacacagt gacgaaaggc
    23821 gcgattgaag acgcggtgca cacgaaaagc ttaacaactg ttgaggaagt caagcactgc
    23881 accaaagcct ctgggtcctg cggaggatgc aaaccgctcg ttgaagacct tttgaggtac
    23941 atgaccaaca gcgaatatac gaagcccgcc ggcacacttt cgttttgcgg ctgtactgat
    24001 tttacagaag acgacatcat cgctgagctt cagcgcaggc cattcactaa tccggcagaa
    24061 gtgatgaacc agcttgactg gaaaacaaaa aaaggatgca gtacttgtgt tcctgcgatt
    24121 caatactatc tggaaatgct gtaccccggg tttgtacagc ctgagccagc cactgaagag
    24181 acatgcatcc tgattccgca aatgtacggg gggcggacaa acgcggatca gctaagaacc
    24241 atcgctaaca tcattgaggc atacagcatt tccgacgtat ccatcactca cggccaaagg
    24301 ctgaagcttt ccgggatcaa gcctgcggat ctcccgaaca tgaaaaaaga cctgaaaatg
    24361 cccgtttaca ctaatgaaca ccgacacacg ctgcaaacca tcaaagcatg tacatgcggg
    24421 caaaatcgat cgattcagca gctggcagcc caaatcgaaa gacaacttga gacgcttccc
    24481 ttacccgctc ccatttctat cagcttatca tgtgaaacag actgcaccga tgccgccctg
    24541 caagatgtcg gcgcaattcg gacacaagct ggctgggaca tttacatcgg cggcgtccgg
    24601 ggaactcatg cccgttcagg agctctgttt tgcgtgactg agaacgaaga cagcactgcc
    24661 ggcatgatca aaggactgat ccagtattat cgggaaacgg ctcattactt agaagctgtt
    24721 catcagtgga tagaccgtct cgggatcgtt catatcagag aagtgctatt cgaagaagac
    24781 ctaagggcac agctgctgga aagcctccaa acagatctgt cactgattca aaacccgact
    24841 gtagagacgg gcgcatataa gaaaggatga gacattttga ctgaacgact gcttagatat
    24901 ttccgagata aacagcaaga cgtccaatca gaaaaaacat atgacaccca atgcccgttt
    24961 tgcagcatgc agtgcaaaat gcagctcgtg gaacaaacca tcgtcacgcg caaaaagtac
    25021 actgcgatcg ggattgataa tcctacgaca cagggtcggc tatgcatgaa gggcatgaat
    25081 gctcaccagc atgccttgaa ctcctctcgc atcacccgcc ctctgctgaa gaaaaacggc
    25141 gagtttatcc ctgtttcctg ggaagaagca ttgaattaca ttaaagacca agtgacaatg
    25201 atccaagcag aacacggcca tgacgccatg gcggtatacg gaagcgcctc gattacaaat
    25261 gaagaggcat atttgttagg gaaattcgca cgggtgggct tacagacaaa atacatcgac
    25321 tacaacggga ggctttgtat gtccgccgca gcaaccgcag ccaaccaaac attcggcgca
    25381 gacagaggct taacgaatcc cttatcagac attccccaca cccgtgtgat cattctggcc
    25441 ggcaccaata tcgcggagtg tcagcctacg attatgccat attttgaaaa agcgaaagaa
    25501 aacggagctt acatcattgc cattgatccg cgtgaaacag caacaacaaa aatcgccgat
    25561 cttcatctga aaatcaaacc cggcacagac gccgcccttg ccaacggtct cgtcaaaatc
    25621 atcattgacg aacagcttat aaacgaggat ttcattcaat cacgaacaaa tggattcgaa
    25681 gagctgaagc agcatactga ctcgttggac ctgaatgaca tcgccgaaca gacgagtgtc
    25741 ccgctggcgg atataagaaa agctgctgta aagtttgcca aggaaacgtc cggcatgctg
    25801 tttacagccc gagggattga acagcaaacc gatggaacag cggctgtgaa aggcttctta
    25861 aacatggtgc tgatcacagg aaaaatcggc aagccttact caggttacgg ggcgatcacc
    25921 ggacaaggca acgggcaagg tgcaagagag catggccaaa aagccgatca gcttccgggc
    25981 tatcgatcta ttgaaaacga acaacaccgg gcacatgttg cgaaagtgtg gggaatccat
    26041 caggatgatc tgccgcgaaa aggtgtctca gcctatgaaa tgatggaaaa aatcaatgac
    26101 ggcgacatca aaggattgtt cctcatgtgc tccaatcctg ctgtctccag tccaaatgcg
    26161 aatctcgtga aaaaggcttt acgtaaactg acattctttg ttgcaatcga tttgtttatt
    26221 tctgagactg cgaaatacgc agatgtgatt ttacccgcct cctcttactt agaagatgaa
    26281 ggcaccatga caaatgtaga aggacgcgtg acattaagag aagcaagccg gccatgtccc
    26341 ggcgaagcaa agcatgattg gcagatcatt tgtgatctcg catccgctct cggcaagggc
    26401 cgctactttt cttatacgtc agcggaggat atttttaatg aattgagaga agcgagccga
    26461 ggcgggattg ccgattattc aggcatctca tacggcaggc tcagacgtga aggcggcatt
    26521 cattggccgt gtccggaatc tgatcatccc ggaactgggc gcttgtttac agaatcattt
    26581 gctcatccgg atcaaaaagc ggcattaagt gtgattccaa acgaaccacc tgttccaaaa
    26641 gagaagccga cagccgatta tccgctttat ttaacgacag gcagagtcat gtctcactac
    26701 ttaacaggcg tccaaacaag aaaaagcgcc gcccttgccg cgagacattt tgaatcgttt
    26761 atggaaatcc atccgcaaac agcagcgacc tacaatatcg aggaccgtgt actggtaaaa
    26821 atagaatcgc cgcggggaag catcaccgtc cgcagcaaat tatcagaaca aatcagaaaa
    26881 gatactgtct ttgttcccat ccattgggca gacgctcaaa atgtgaatga tttaatcgga
    26941 gaagccttag atccagcctg taaaatgccc ggttttaagg tatgcgccgt ccgaatcaga
    27001 cctatttaaa tttttcataa aatttttaga acttttcgta tattttgtta cattttataa
    27061 catgtatctt aaatattcct ttttgctgtg ctacgctgga aaaaacattg ataaggagcg
    27121 gatcatctga tgggaaaaaa acagctagtt cttgttggta atggaatggc cggggtaagg
    27181 gccattgaag agatactgag tgttgctaaa gacgagtttc agatcacaat tttcggtgcc
    27241 gaaccgcatc ccaattacaa ccgaatcctt ttgtcaaaag tgcttcaagg cgatacagat
    27301 attaaagata ttacgttaaa cgattgggac tggtacgaag aaaacaacat tcaattgtat
    27361 acaaatgaaa cagtcatcaa agtggacacg gaaaacaaaa cagtcatcac agatgcagac
    27421 agaatccagc cttacgatga attgatcctg gcgacaggct cggtcccttt tatccttccg
    27481 attccgggcg cagacaaaaa aggcgtcaca gctttccggg acataaaaga tacagacaca
    27541 atgctcgccg cgtcaaaaca atataaaaaa gctgccgtca tcggcggagg acttcttggt
    27601 ttggaagcag ctcgcggact gctgaatctt ggcatggatg tgtccgtcat ccaccttgcc
    27661 ccattcctga tggagcgcca gcttgatgca acggcaggac gcctgctgca aaacgagtta
    27721 gaaaaacaag gtatgacctt tttacttgaa aagcaaacag aagaaattgt cggtgacgac
    27781 cgtgtcgaag gcctccgatt caaggatggc acaagcattg aagctgattt agtcgtcatg
    27841 gctgtcggca tccgcccaaa tacaacgctc ggggccgaga gcggcattcc ggttaaccgc
    27901 ggcatcatcg tcaacgatta tatgcagact gaaatcccgc acatttacgc ggtcggcgaa
    27961 tgtgccgagc accgaggaat cgcctacggg cttgtggcgc cgctgtatga acaggcaaaa
    28021 gtgctggcaa agcatatttg cggcatcgaa acaaaaccgt atgagggctc cgttctctcc
    28081 acacagttaa aggtatcagg cgtcgaggtc ttctctgccg gtgactttaa cgaatcagag
    28141 gagaaaaaag cgattaaagt cttcgatgag caggacggca tctataaaaa aatagtcctg
    28201 agaggcaatc aaattgtcgg t
//
