LOCUS       NZ_SHKU01000005        31149 bp    DNA     linear   CON 27-MAY-2024
DEFINITION  Streptomyces sp. BK022 Ga0307664_105, whole genome shotgun sequence.
ACCESSION   NZ_SHKU01000005
VERSION     NZ_SHKU01000005.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. BK022
  ORGANISM  Streptomyces sp. BK022
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 607918)
  AUTHORS   Kalluri,U.
  TITLE     Understanding the reciprocal impacts of modified plant cell wall and
            associated microbiome
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 607918)
  AUTHORS   Kalluri,U., Huntemann,M., Clum,A., Pillay,M., Palaniappan,K.,
            Varghese,N., Mikhailova,N., Stamatis,D., Reddy,T., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-FEB-2019) Prokaryotic Super Group, DOE Joint Genome
            Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.12.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 215.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004217355.1-RS_2024_05_27
            Annotation Date                   :: 05/27/2024 02:58:00
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,482
            CDSs (total)                      :: 6,401
            Genes (coding)                    :: 6,280
            CDSs (with protein)               :: 6,280
            Genes (RNA)                       :: 81
            rRNAs                             :: 5, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 16S)
            partial rRNAs                     :: 3, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 121
            CDSs (without protein)            :: 121
            Pseudo Genes (ambiguous residues) :: 0 of 121
            Pseudo Genes (frameshifted)       :: 49 of 121
            Pseudo Genes (incomplete)         :: 92 of 121
            Pseudo Genes (internal stop)      :: 16 of 121
            Pseudo Genes (multiple problems)  :: 29 of 121
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:05:10
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 145644
            Orig. end                         :: 176793
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            SHKU01000005.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..31149
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NI-siderophore"
                     /region_number="1"
                     /rules="IucA_IucC"
                     /tool="antismash"
     cand_cluster    1..31149
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="IucA_IucC"
                     /kind="single"
                     /product="NI-siderophore"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..31149
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[14000:17149]"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      14001..17149
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
     gene            complement(120..1109)
                     /locus_tag="EV284_RS21760"
                     /old_locus_tag="EV284_4365"
     CDS             complement(120..1109)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1205: ABC
                     transporter, carbohydrate uptake"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018571655.1"
                     /locus_tag="EV284_RS21760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_4365"
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="WP_207229102.1"
                     /transl_table=11
                     /translation="MTAAGAFALLACVSLTACSSTGGKKAEDARKAATAQGRAAVTTPR
                     WTIAMITHSGDGDTFWDIVQSGAKQAAVKDNINFLYSHDDEAQQQAQLVDAAIDKKVDG
                     IIVSLAKPDALKAAVARARKAGIPVVTVNSGSAQSKAFGALSHIGQDETIAGEAVGEEL
                     NKRGRKNALCVLHEQGNVGHEQRCDGVEKTFHGKVSKLYVNGTNMPDVQSAVGAKLQAD
                     RDVDAVVTLGAPYADTVVKAKADAGSKAEVDTFDLNAKVAAELKDGTLGFAVDQQPYLQ
                     GYEAVDLLWLYKYNGDVLGGGKPVLTGPQIITRDQAGALAAYTDRGTR"
     misc_feature    complement(1250..1264)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.74"
                     /tool="antismash"
     misc_feature    1251..1265
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.58"
                     /tool="antismash"
     gene            complement(1285..2034)
                     /locus_tag="EV284_RS21765"
                     /old_locus_tag="EV284_4366"
     CDS             complement(1285..2034)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972670.1"
                     /locus_tag="EV284_RS21765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_4366"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_130337452.1"
                     /transl_table=11
                     /translation="MDPTAPLGLRVDRSSPVPLYFQLAQQLEAAIERGALTPGSLLGNE
                     IELAARLGLSRPTVRQAIQSLVDKGLLVRRRGVGTQVVHSQVKRPLELSSLYDDLEAAG
                     QRPATKVLVNTVVPATAEIAAALGVTEGHDVHRVERLRLAHGEPMAYLTNHLPLGLLDL
                     DTARLEATGLYRLMRSAGITLHSARQSIGARGATLAEAERLAEPEGAPLLTMRRVTFDD
                     TGRAVEQGDHTYRPARYSFEFQLLVRP"
     misc_feature    complement(2131..2144)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.84"
                     /tool="antismash"
     gene            2154..3176
                     /locus_tag="EV284_RS21770"
                     /old_locus_tag="EV284_4367"
     CDS             2154..3176
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016431804.1"
                     /locus_tag="EV284_RS21770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_4367"
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="WP_130336786.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 4e-19, bitscore:
                     64.5, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 1e-25, bitscore:
                     85.1, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIGVIGTGRIGAIHANTLSRHREVGSLILTDSDPLRAQELAHRL
                     GETAAPGVDEVFQWGVDAVVITTATAAHAELIGRAARSGLPVFCEKPIALDLPGTLHAL
                     AEVAAAGTVLQMGFQRRFDAGYVGAREAVRSGRLGRLHTVRALTSDQSPPPREWLPLSG
                     GLFRDTLIHDFDILRWVTGREVTDVYATGSDAGPPMFREAGDVDTGAALLTLDDGTLAT
                     ATATRLNGAGYDVRMELSGELDTVVVGLDDRTPVASTEPTGPPPADRPWPGFLERFGTA
                     YESELCTFVDVVRGEHPNPCDGWQALQALRVAEACEISRRERRAVALTEVPDRLRSSYV
                     "
     misc_feature    2259..2261
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(3253..3648)
                     /locus_tag="EV284_RS21775"
                     /old_locus_tag="EV284_4368"
     CDS             complement(3253..3648)
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0004521 - RNA endonuclease activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020119054.1"
                     /locus_tag="EV284_RS21775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_4368"
                     /product="ribonuclease domain-containing protein"
                     /protein_id="WP_130336788.1"
                     /transl_table=11
                     /translation="MRFPPRTTRIGAAAALFSALLLGGTVSATTADAATASVGSICYGS
                     LPSQAYDTLDLIAQGGPDPYSQDGVVFQNREGVLPGQSSGYYHEYTVITPGESTRGARR
                     IVTGQRTQEDYYTSDHYATFDLVDYGC"
     misc_feature    complement(3673..3684)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     misc_feature    3773..3790
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 20.42"
                     /tool="antismash"
     gene            complement(3788..4396)
                     /locus_tag="EV284_RS21780"
                     /old_locus_tag="EV284_4369"
     CDS             complement(3788..4396)
                     /GO_function="GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983433.1"
                     /locus_tag="EV284_RS21780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_4369"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_130336790.1"
                     /transl_table=11
                     /translation="MGKLVSTVFVSLDGVYQAPGGPDEDTSGGFGQGGWTFPYADDGFG
                     GFVAESFGRAGAFLLGRHTYDIFAGYWPKVTDPENPVAARLNELPKYVVSATVENPGWA
                     GTTVLSGDLGKEVQALKERTEGEVQIHGSGALVRSLVNLGLIDTLHLLTFPVVLGEGRR
                     LFVEGAVPTRFRHAGGTVTGKGVSIQSYDLAGRPEYGSF"
     gene            complement(4484..5614)
                     /gene="alc"
                     /locus_tag="EV284_RS21785"
                     /old_locus_tag="EV284_4370"
     CDS             complement(4484..5614)
                     /EC_number="3.5.3.4"
                     /GO_function="GO:0004037 - allantoicase activity [Evidence
                     IEA]"
                     /GO_process="GO:0000256 - allantoin catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="alc"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972679.1"
                     /locus_tag="EV284_RS21785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_4370"
                     /product="allantoicase"
                     /protein_id="WP_130336792.1"
                     /transl_table=11
                     /translation="MTAQQPSDPPRFTGDAAPYGGGDPYADYRTADFPFAHHPDLADRR
                     LGAAVIAANDEFFAERENLLLPHRAEFEPGRFGHKGKIMDGWETRRRRGPSAEEPWPGA
                     DDHDWALIRLGTPGVIRGIVVDTAHFRGNHPQAVSVEATSAPGNPSPEELLGDDVKWTT
                     LVPLTPVGGHAANGFPVSAPQRFTHLRLNQHPDGGVARLRAYGEIVPDPEWLATLGTFD
                     VAALENGGRAEDASDRFYSPAANTVRPGRSQRMDDGWETRRRRDRGHDWITYRLTEQAL
                     VRAVEIDTAYLKGNSAGWASVSVRDGESGEWTEILPRTRLQPDTNHRFPLPAAAVGTHA
                     RVDIHPDGGISRLRLFGSLTEAGAGRLAARFRELDG"
     gene            complement(5651..6973)
                     /gene="allB"
                     /locus_tag="EV284_RS21790"
                     /old_locus_tag="EV284_4371"
     CDS             complement(5651..6973)
                     /EC_number="3.5.2.5"
                     /GO_function="GO:0004038 - allantoinase activity [Evidence
                     IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0050897 - cobalt ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0000256 - allantoin catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="allB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020119051.1"
                     /locus_tag="EV284_RS21790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_4371"
                     /product="allantoinase AllB"
                     /protein_id="WP_130336794.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 4.7e-22, bitscore:
                     73.6, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDDVELALRSTRVVTPEGVRAATVTVAGGTIEAVLPYEAGVPAV
                     DLGDDALLPGLVDTHVHVNDPGRAEWEGFWTATRAAAAGGVTTLVDMPLNSLPPTTTVD
                     HLRVKREAAQGRTHVDVGFWGGALPGNVKDLRPLHEAGVFGFKAFLSPSGVDEFPHLDS
                     ARLARSLAEIAGFDGLLIVHAEDPAHLTDAPAGPAYAGFLASRPHAAETNAIAQLLGLA
                     RTLDARVHVLHLSSAAALPLIAAARAEGVRVTVETCPHYLTLSAEEVPDGASEFKCCPP
                     IREAANRDLLWQALADGTIDCVVTDHSPSTADLKTPDFATAWGGISGLQLSLPAIWTEA
                     RERGHRLTDVVRWMSARTAALAGLDRKGAIAPGRDADFAVLAPEGTFTVDPARLHHRNP
                     VTAYAGKTLHGVVKSTWLRGQRVYSEGEFTAPKGRLLTRTG"
     misc_feature    complement(7012..7029)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 17.04"
                     /tool="antismash"
     gene            7316..7942
                     /locus_tag="EV284_RS21795"
                     /old_locus_tag="EV284_4372"
     CDS             7316..7942
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018847739.1"
                     /locus_tag="EV284_RS21795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_4372"
                     /product="nucleotidyltransferase family protein"
                     /protein_id="WP_130336796.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 4e-38, bitscore:
                     126.3, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSDQAPRHPRVTGLLLAAGGGRRLGGRPKALLRHDGALLVERAA
                     RALRDAGCARVHVVLGAGSEEVRAEAELSGCVLVENPGWGEGMGSSLRAGLRSLGGTDA
                     RGALVGLVDQPGVGAEAYARVLDAFTGETSLVSAAYDGTRGHPVLLGAAHWAGVTESAQ
                     GDQGAREYLRRHSAEIRLVECGDVAEAYDIDTAADLGRLRPGGAH"
     gene            8008..9630
                     /gene="aceB"
                     /locus_tag="EV284_RS21800"
                     /old_locus_tag="EV284_4373"
     CDS             8008..9630
                     /EC_number="2.3.3.9"
                     /GO_function="GO:0004474 - malate synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="aceB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020133434.1"
                     /locus_tag="EV284_RS21800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_4373"
                     /product="malate synthase A"
                     /protein_id="WP_130336798.1"
                     /transl_table=11
                     /translation="MSAPASPPVVVDAEPLPRQEEVLTGPALDFLAELHRRFTPRRNEL
                     LARRTERRAEIARTGTLDFLPETAAVRADDSWRVAPAPPALRDRRVEITGPADRKMTVN
                     ALNSGARIWLADFEDASSPTWENVVLGQLNLMDAYAGRVDFTDARTGKSYALRPQEELA
                     TVVMRPRGWHLDERHLEGADGEPLPGALVDFGLYFFHNAARLLELGKGPYFYLPKTESH
                     LEARLWNDVFVFAQDHLGIPQGTVRATVLIETITAAYEMEEILYELRDHASGLNAGRWD
                     YLFSIVKNFRDGGPEFVLPDRNLVTMTAPFMRAYTELLVRTCHKRGAHAIGGMAAFIPS
                     RKDAEVNKVAFEKVRADKDREAADGFDGSWVAHPDLVPIAMESFDKVLGDRPHQKDRLR
                     EDVHVKAADLIDIASLDAKPTYAGLVNAVRVGIRYIEAWLRGVGAVAIFDLMEDAATAE
                     ISRSQIWQWINAGVEFENGERATPELARRLAAAELEAVRAEIGAEAFAAGHWQEAHDLL
                     LTVALDEEYADFLTLPAYRRLTG"
     gene            complement(9637..9906)
                     /locus_tag="EV284_RS21805"
                     /old_locus_tag="EV284_4374"
     CDS             complement(9637..9906)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019061968.1"
                     /locus_tag="EV284_RS21805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_4374"
                     /product="SelT/SelW/SelH family protein"
                     /protein_id="WP_130336800.1"
                     /transl_table=11
                     /translation="MSHRVEIEYCTQCRWLPRAAWLAQELLTTFETELEALALKPGTGG
                     VFVVRVDGEPVWDRREQGFPEPTAVKRLVRDRVAPERSLGHSDK"
     gene            complement(9917..10831)
                     /locus_tag="EV284_RS21810"
                     /old_locus_tag="EV284_4375"
     CDS             complement(9917..10831)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016823965.1"
                     /locus_tag="EV284_RS21810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_4375"
                     /product="HipA family kinase"
                     /protein_id="WP_130336802.1"
                     /transl_table=11
                     /translation="MLREVAATRYVEPLHTGGSVPAVVEADDLGTYVVKFTGSAQGRKA
                     LVAEVIVGELARALGLRFPELVLVHFDPAVAADEPHQEVRDLHDASAGVNLGMDYLPGA
                     RDLTPEIARNFPVDPLEAGRIVWLDALTANVDRTVHSSNLMVWPTFGTAPPRLWLIDHG
                     AALVFHHRWDTTNPGRRYDFRHHALGQYGPDVRAADAELAPQVTEELLRGILAEVPDAW
                     LTDDPAFAGPDEARAAYVDHLLARARLSAEWLPTDFPDRAELAAEEAARAERSQRGRPD
                     WLKRVPDLHGRPAAEQDWSVHLG"
     gene            11494..11697
                     /locus_tag="EV284_RS21820"
                     /old_locus_tag="EV284_4377"
     CDS             11494..11697
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA]"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1255: cold-shock
                     DNA-binding domain protein"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020119326.1"
                     /locus_tag="EV284_RS21820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_4377"
                     /product="cold-shock protein"
                     /protein_id="WP_030817331.1"
                     /transl_table=11
                     /translation="MAAGTVKWFNAEKGFGFIEQDGGGADVFAHYSNIAAQGFRELLEG
                     QKVNFDIAQGQKGPTAENIVLA"
     gene            12049..13467
                     /locus_tag="EV284_RS21825"
                     /old_locus_tag="EV284_4378"
     CDS             12049..13467
                     /EC_number="3.6.4.-"
                     /GO_function="GO:0004386 - helicase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1122: ATP-dependent
                     RNA helicase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014145517.1"
                     /locus_tag="EV284_RS21825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_4378"
                     /product="DEAD/DEAH box helicase"
                     /protein_id="WP_130336804.1"
                     /transl_table=11
                     /translation="MNRTRTNDRFARSRHGNSGRRAPAVQGEFALPRTTTPALPAVEGF
                     ADLDMPGELLAALGAQGVSVPFPIQAATLPNSLAGRDVLGRGRTGSGKTLAFGLALLAR
                     TAGRRAEARQPLALVLVPTRELAQQVTDALAPYARSVRLRLATVVGGMSIGRQASALRG
                     GAEVVVATPGRLKDLIDRGECRLDQVSVTVLDEADQMADMGFMPQVTALLDQVRPEGQR
                     MLFSATLDRNVDLLVRRYLSDPVVHSVDPSAGAVTTMEHHVLHVHGADKHAATTQIAAR
                     DGRVIMFLDTKHAVDRLTEHLLNSGVRAAALHGGKSQPQRTRTLAQFKTGHVNVLVATN
                     VAARGIHVDNLDLVVNVDPPTDHKDYLHRGGRTARAGESGSVVTLVTPSQRRDMNRLMT
                     DAGIRPQTTQVRSGDETLNRITGAQAPSGIPVVITAPVADRPKRRRAPARGRRHQAPAA
                     RRAPALQSTAGAAA"
     misc_feature    complement(13473..13486)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.39"
                     /tool="antismash"
     gene            13513..13917
                     /locus_tag="EV284_RS21830"
                     /old_locus_tag="EV284_4379"
     CDS             13513..13917
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030532.1"
                     /locus_tag="EV284_RS21830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_4379"
                     /product="CBS domain-containing protein"
                     /protein_id="WP_130336806.1"
                     /transl_table=11
                     /translation="MMLGKLHTRSVSVRPVRGTVAGSVDAAGPQVWYDMTVEVALSVMA
                     AARTEYLVVCDEDGLCVGLVTQSQLTAVRDSAGYTDRLRLDGITDSREPSGPPWATREG
                     AEKGTPPGRLGPVRVVDEHGDALGVLAGSR"
     gene            complement(14001..15527)
                     /locus_tag="EV284_RS21835"
                     /old_locus_tag="EV284_4380"
     CDS             complement(14001..15527)
                     /GO_process="GO:0019290 - siderophore biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015493384.1"
                     /locus_tag="EV284_RS21835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_4380"
                     /product="IucA/IucC family protein"
                     /protein_id="WP_130336808.1"
                     /sec_met_domain="IucA_IucC (E-value: 8.7e-47, bitscore:
                     154.7, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERVDLNPPTDAARRADAYASAPLLNCLLREVARPVPERGDRPVY
                     RLPGTGRLLRVRPGRRPAEPEVRADGAWQPLSHAELVKLVAEELRAHTGLPGDDLPAEM
                     LDSRDTVAALLAARARAVAPEDPYLRSEQSLITGHPHHPAPKARGGGPVAAWLPYAPEA
                     HARFPLVLLGVREDQVAEEGDTRALDALGTAPPGYRLLPAHPWQLDLLAPGLAPAFADR
                     RLIRLGTTESAVRPTAAVRTVYEPGRDLFLKFSLDVRITNDIRRLWRHDLQRLDRSDTA
                     AREAFAAMGPPAAWLSDRGYRTAAFAFEELAVLVRDGLRGHLLPGATPLLAAGLAEGFD
                     GSPLAAAPDPDAWWAAYLRQVVPPALRAFDEYGVVVEAHLQNTLVAVDAAGMPVQALFR
                     DAEGVKLLSDVGREAGWERLVYCLLVNHLGEIAAALAEAHPGLDPWPALRAELSRHPLP
                     EIPALLAAPALPGKTNLLLRWTGADGADARYLPLPNPLRAGDAVRGGRDR"
     gene            15632..17149
                     /locus_tag="EV284_RS21840"
                     /old_locus_tag="EV284_4381"
     CDS             15632..17149
                     /GO_process="GO:0019290 - siderophore biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018547072.1"
                     /locus_tag="EV284_RS21840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_4381"
                     /product="IucA/IucC family siderophore biosynthesis
                     protein"
                     /protein_id="WP_130336810.1"
                     /sec_met_domain="IucA_IucC (E-value: 2.5e-36, bitscore:
                     120.4, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYHSPTAEAEVAEELAAVRPALRDRCTAALPGARAAVLTRLWRAL
                     AHEPLPWVASRTPGAHGLTVRLADGRALHGPHSDPYATGDRVHEVRLGRERYADPARLM
                     TDLAVPHAAAFAAELANSVASLALSRADAAEPGAGWPERDWEWEQRVVDGHPFHPNCRS
                     RPGFSVADQLAYGPEHRPVVELGTVAVPAGECLVSGEWPAGLRSGDDLLLPVHPWQAAH
                     VLKRSTEPWRPAHPLMSLRTLALPGGPHVKTSLSARLTSSVRDISAYSVRASADLSVLA
                     AELVGRMDGLLEVTHTIGAATAHSPDLAVLLRESPEEYLAQGERVLPVAALATTALPRS
                     PGWLAAFTRLTLTAGLRLLDLGVALEAHGQNLLVVLAPDDTPLRLIYRDLADIRVSPAR
                     LARHGISSGELTGRLITDDELALRRKLFGSMVGGALAATAGSGPALGAALRAALPDLPR
                     TPDLAALCENPLPVKALTLMRLSPETPGDLWTELPSPFVLERDTYDQ"
     gene            17159..18424
                     /locus_tag="EV284_RS21845"
                     /old_locus_tag="EV284_4382"
     CDS             17159..18424
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019071193.1"
                     /locus_tag="EV284_RS21845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_4382"
                     /product="VWA domain-containing protein"
                     /protein_id="WP_130336812.1"
                     /transl_table=11
                     /translation="MIRRQRLAAGVCALLAALAAGIACPGGAAADETEPQPAPKVELVL
                     DVSGSMRTRDIDGGTRMAAAKQAFNEVLDATPEEVQLGIRTLGANYRGNDRREGCKDTE
                     RLYPVGPLDRTEAKTAVATLAPTGWTPIGPALLKAADDFGTGDGTRRIVLISDGEDTCQ
                     PLDPCEVAREIAAKGIGLTIDTLGLVPDAKTRDQLSCIADATGGTYTSVQHKEELTDRV
                     GQLVERAADPVVTPVATEGTDACAGAPALKSGLYTDREEFGKQRWYKVDVRPGQELRAS
                     VSVADDRATNPNYGVLLRAVTQQGREIVRGEGAGTGRTDAISTGLRYPKPESDDDDATP
                     ETVCLQVTHSFSAGAGVKTTPGMPLELTVDVVDGPSASSDVASFGLGRGWWLLAALVLT
                     GFVAGLLWGWLSRWRVAVWRTN"
     gene            18424..19224
                     /locus_tag="EV284_RS21850"
                     /old_locus_tag="EV284_4383"
     CDS             18424..19224
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018547074.1"
                     /locus_tag="EV284_RS21850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_4383"
                     /product="hypothetical protein"
                     /protein_id="WP_130336814.1"
                     /transl_table=11
                     /translation="MRAIRVLSAALLTLGLAAAPAAADSSPSPSASADGKAPTQAGTSF
                     RTAAEMDQGQTATASASTGDYLYWSFPADTGQRPTVKATVKLPDAHAAQTWQLDVYDGL
                     RRHQSCQYGAATRTAGQGTATVDLTCVLRTVRAWSEPWANDPLPGTYYVRLTVLNLGSA
                     DLGLPVRAEVRADSRNIGGAAAVDGSLGKPLVPGIAVEPEAEKDGSKSAVLSAIEPDDG
                     WSSHWWSSRWVWTAAGGVLAALAGIGGYALTRGRGRPAYVPPGA"
     gene            complement(19260..19895)
                     /locus_tag="EV284_RS21855"
                     /old_locus_tag="EV284_4384"
     CDS             complement(19260..19895)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019985051.1"
                     /locus_tag="EV284_RS21855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_4384"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_130336816.1"
                     /transl_table=11
                     /translation="MPPRRRYDQYCSAARALDLVGDRWTLLIVRELLAGPRRYTDLHAD
                     LPGVSTDVLASRLKDMERDAITARRRLPPPGAAYVYELTPRGRGLLPVLHALGEWGSPE
                     LAEPRPTDAVRAHWSALPLLAVLNAAELGAGVAEVSTEDGEFHLYVGTEDGPAYGHGPA
                     PVAADARLVMDAATCVEVCRGETGIADAVRAGRVTVTGGGTLAKALLK"
     gene            19981..21189
                     /locus_tag="EV284_RS21860"
                     /old_locus_tag="EV284_4385"
     CDS             19981..21189
                     /EC_number="2.6.1.-"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (33-379). E-value:
                     2.2e-51. Score: 167.0. Matches aSDomain:
                     nrpspksdomains_EV284_RS21860_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007390030.1"
                     /locus_tag="EV284_RS21860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_4385"
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="WP_130336818.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.8e-50, bitscore:
                     167.1, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 1.8e-07,
                     bitscore: 25.7, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFRQSNKLSEVCYEIRGPVIQHADALEEAGHSVLRLNTGNPALF
                     GFEAPEEITQDMIRMLPRAHGYTDSRGVLSARRAVAQRYQTLGLQVDVDDVFLGNGVSE
                     LVSMAVQALVEDGDEVLIPAPDFPLWTAVTTLAGGRAVHYLCDEQSDWAPDLADMASKI
                     TDRTKAVVIINPNNPTGAVYPKEIVEGILDLARRHGLMVFADEIYDQILYDGAVHHSAA
                     ALAPDLVVLTFCGLSKTYRVAGFRSGWLVVTGPKQHAKSYLEGLTMLASMRLCPNAPAQ
                     YAIQAALGGRQSIHELTAPGGRLYEQRNVAWEKLNEIPGVSCVRPKGALYAFPRLDPKV
                     HKIHDDEKFVLDLLLREKIQVVQGTGFNWPAPDHFRILTLPYADDLEAAIGRIGRFLSG
                     YRQ"
     aSDomain        20080..21117
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EV284_RS21860_Aminotran_1_2.1"
                     /evalue="2.20E-51"
                     /label="EV284_RS21860_Aminotran_1_2.1"
                     /locus_tag="EV284_RS21860"
                     /protein_end="379"
                     /protein_start="33"
                     /score="167.0"
                     /tool="antismash"
                     /translation="VLRLNTGNPALFGFEAPEEITQDMIRMLPRAHGYTDSRGVLSARR
                     AVAQRYQTLGLQVDVDDVFLGNGVSELVSMAVQALVEDGDEVLIPAPDFPLWTAVTTLA
                     GGRAVHYLCDEQSDWAPDLADMASKITDRTKAVVIINPNNPTGAVYPKEIVEGILDLAR
                     RHGLMVFADEIYDQILYDGAVHHSAAALAPDLVVLTFCGLSKTYRVAGFRSGWLVVTGP
                     KQHAKSYLEGLTMLASMRLCPNAPAQYAIQAALGGRQSIHELTAPGGRLYEQRNVAWEK
                     LNEIPGVSCVRPKGALYAFPRLDPKVHKIHDDEKFVLDLLLREKIQVVQGTGFNWPAPD
                     HFRILT"
     gene            21261..21875
                     /locus_tag="EV284_RS21865"
                     /old_locus_tag="EV284_4386"
     CDS             21261..21875
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675830.1"
                     /locus_tag="EV284_RS21865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_4386"
                     /product="hypothetical protein"
                     /protein_id="WP_130336820.1"
                     /transl_table=11
                     /translation="MARPPTAAQRRVVEGADPGTGRLRGTAAQLAALVRLGLAFRHPRP
                     PHDHFLTPAGHRLREAGPEPASAPAPAAPAGVFAARVGGAEEAAPGPSRMREVRDAWQG
                     LMELRRMTNPDSATDRPCGWERTHLVRAAALALEAAGHGPEHAGTPGYRVRATPQPEAV
                     AVYGPALQPYAATLEAAGWQCGEYTEARTRTRHLLASPRRV"
     gene            complement(21883..23250)
                     /locus_tag="EV284_RS21870"
                     /old_locus_tag="EV284_4387"
     CDS             complement(21883..23250)
                     /EC_number="3.5.4.32"
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019521899.1"
                     /locus_tag="EV284_RS21870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_4387"
                     /product="8-oxoguanine deaminase"
                     /protein_id="WP_130336822.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 3.1e-62, bitscore:
                     205.7, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPAERIVIENCAIATVDADDTEYATGHLVLAGDRIESVGAGPAP
                     AGLTGVIRRIDAGGHLATPGLVNTHHHFYQWLTRGLATDHNLFEWLTALYPTWARIDED
                     MVSAGARGSLAMMARGGVTTAMDHHYVYPRGTGDLSGAIVRAARDTGVRFTLARGSMDR
                     GESDGGLPPDFAVESLDEALAATEATVAEHHDPSFGALTQVAVAPCSPFSVSTELMKQG
                     AELARRLGVRLHTHGSETVEEEKFCHELFGMGPTEYFESTGWLGEDVWMAHCVHMNDSD
                     ITAFARTGTGVAHCPSSNARLAAGIARVPDLLAAGVPVGLGVDGTASNESGELHTELRN
                     ALLVNRLGPHREAALTTRQALRLGTYGGAQVLGRAAETGSLEPGKLADLVLWRMDTLAH
                     ASIADPVAALVLGAPAPVTASFVGGRQIVADGRLLHVDEDAIARTTREQARRLARS"
     gene            complement(23267..24181)
                     /gene="pucL"
                     /locus_tag="EV284_RS21875"
                     /old_locus_tag="EV284_4388"
     CDS             complement(23267..24181)
                     /EC_number="1.7.3.3"
                     /GO_function="GO:0004846 - urate oxidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0019628 - urate catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pucL"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018092787.1"
                     /locus_tag="EV284_RS21875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_4388"
                     /product="factor-independent urate hydroxylase"
                     /protein_id="WP_130336823.1"
                     /transl_table=11
                     /translation="MAETSRPSGPAILGQNQYGKAENRVVRITRDGATHHIKDLNVSVT
                     LGGDMDDVHYSGSNAHVLPTDTTKNTVYAFAKRYGIESAEQFGIHLARHFVTSQEAIRT
                     ARIRIEEYAWDRIGAEDGGHSFVRTGQEVRLTQVFHDGTTWQVVSGLGDLVVLNSTDSE
                     FWGYAKDEYTTLPEAYNRVLATEVNARWRYGWTGEGDAPDWDASYAGARRHLLEAFAGT
                     YSYSLQQTLYEMGARVIGERAEIDEIRLSLPNKHHFLADLTPFGLTNDNEVYLAADRPY
                     GLIEATVLREGREAAIPVDLTNL"
     gene            complement(24187..24531)
                     /gene="uraH"
                     /locus_tag="EV284_RS21880"
                     /old_locus_tag="EV284_4389"
     CDS             complement(24187..24531)
                     /EC_number="3.5.2.17"
                     /GO_process="GO:0019628 - urate catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="uraH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015656872.1"
                     /locus_tag="EV284_RS21880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_4389"
                     /product="hydroxyisourate hydrolase"
                     /protein_id="WP_130336825.1"
                     /transl_table=11
                     /translation="MTTTASVSTHILDTSLGRPAPGVTVRLSARTASGADWRPLGEGTT
                     DADGRCRDLPAPPGDTARVRLDFAVEPYLRERGDAFFPEVTVTFAVRAGEHYHVPLLLS
                     PFGYSVYRGS"
     gene            complement(24546..25049)
                     /gene="uraD"
                     /locus_tag="EV284_RS21885"
                     /old_locus_tag="EV284_4390"
     CDS             complement(24546..25049)
                     /EC_number="4.1.1.97"
                     /GO_process="GO:0019628 - urate catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="uraD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018547082.1"
                     /locus_tag="EV284_RS21885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_4390"
                     /product="2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline
                     decarboxylase"
                     /protein_id="WP_130336827.1"
                     /transl_table=11
                     /translation="MTSPATPLGLARFNALGEDAALAALHEVCASTAWGRLLLVARPYA
                     TPDDLYLAADAALAGLGAGDLAEAMAGHPPIGRPEPGDPASAREQRGMADASGALRAEM
                     LELNLAYQDRFGHVFLICATGLTGEQMRDALTERLGNTPEREREIARAELGRINRIRLA
                     RLVA"
     misc_feature    25124..25139
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.55"
                     /tool="antismash"
     misc_feature    complement(25129..25142)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.96"
                     /tool="antismash"
     misc_feature    25129..25143
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 19.33"
                     /tool="antismash"
     misc_feature    complement(25130..25143)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.52"
                     /tool="antismash"
     gene            complement(25162..25473)
                     /locus_tag="EV284_RS21890"
                     /old_locus_tag="EV284_4391"
     CDS             complement(25162..25473)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018547083.1"
                     /locus_tag="EV284_RS21890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_4391"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_165425628.1"
                     /transl_table=11
                     /translation="MGGELLPPGEAGPDDVVLAWEGAEVVAVRLPQLAESLDHILTALE
                     RREGRPLAELDRKAKQGIVRTLEARGAFAVRHGVETVAGALGVSRFTIYNYLNREKGR"
     gene            complement(25521..25772)
                     /locus_tag="EV284_RS21895"
                     /old_locus_tag="EV284_4392"
     CDS             complement(25521..25772)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983462.1"
                     /locus_tag="EV284_RS21895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_4392"
                     /product="hypothetical protein"
                     /protein_id="WP_130336831.1"
                     /transl_table=11
                     /translation="MRLRVEFTTEPFDLDVPPAHAVAAREVVEGGGLDTVDVGPFGTMA
                     EGGADGVLSAVDALLRRSLQAGATRISLQVNVVGEDGR"
     gene            complement(25861..28269)
                     /locus_tag="EV284_RS21900"
                     /old_locus_tag="EV284_4393"
     CDS             complement(25861..28269)
                     /EC_number="3.2.1.-"
                     /GO_function="GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019056938.1"
                     /locus_tag="EV284_RS21900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_4393"
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="WP_130336833.1"
                     /transl_table=11
                     /translation="MRHALLRAVRRLGTRTAVTAVTTALAVAAPFPAVAASGPEPLSSL
                     VDPLIGSANGGNTFPGATLPQGMIAWSPTSTAGDQTSTGAANGYAYNTTRIRGLSLTHV
                     NGAGCHPGAAGDIPIMPFTGDITSSPSADTKDAVYAANFSHADEKAVPGRYTLGLASGA
                     SADLAVSRRAGVADFAFPAGRPASLLFRVSNSLNGSEDAHIDIDAAHRKVTGWVLTGAF
                     CGRRANGGTNNRKSYYRLHFSATFDRAFATTGTWHDGTLSPGSTTASGGEGYATGADRA
                     GRGSGGWVGFDTASDNDVHMRLGISYVSLAGAEANLRHEIPARAGVADVAAAGARVWDR
                     ELSTVRAEGGSPARRTAFYTALYHSLMQPNLISDTDGRYRGMDQAVHRTARGQRAQYSN
                     FSGWDQYRAQIQLLALLRPTVAGDFAQSLYNFARQNGGVWDRWVHISGATHVMTGDPSA
                     ATLATFYAMGVRNFDYRGAYTSLVRQATVPTPDDLSDAGCPGQCEGQRPNLAQYLVSHY
                     APQDACHCWGGAAETLEDAVADFSLAQWARGLGRDADAKVFTDRAAYWRNVFNPATGHV
                     QARKLDGTWITPFNPASDLGFAQGTSATYTWMVPHDVQGLAGAMGGRNAAATRLDGFFH
                     NPDGSWSVRGGDPLRYDPTNEPGIHAPWLYNALGQPWKTQATVRRILDTVYATGPAGLP
                     GNDDLGTMSAWYVFSALGLYPQTPGSAVLLLGAPVFPKATLVRPGRADLVITAPEADDT
                     HVYTAAVHREGHPVNRSWLTPGEALDGGRLDFALTTAPDTGWATGHLPE"
     gene            28433..28666
                     /locus_tag="EV284_RS21905"
                     /old_locus_tag="EV284_4394"
     CDS             28433..28666
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675814.1"
                     /locus_tag="EV284_RS21905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_4394"
                     /product="hypothetical protein"
                     /protein_id="WP_130336835.1"
                     /transl_table=11
                     /translation="MADPTRYPHIVVHPPALDGSRRVTEGEVTLGLASHLDDVIEILRL
                     ADLDRIEVEESDLIDWIGGGPDDWPGLSEHEL"
     gene            complement(28886..30490)
                     /locus_tag="EV284_RS21910"
                     /old_locus_tag="EV284_4395"
     CDS             complement(28886..30490)
                     /NRPS_PKS="Domain: AMP-binding (23-437). E-value: 7e-111.
                     Score: 362.6. Matches aSDomain:
                     nrpspksdomains_EV284_RS21910_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018571592.1"
                     /locus_tag="EV284_RS21910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_4395"
                     /product="AMP-binding protein"
                     /protein_id="WP_130336837.1"
                     /sec_met_domain="AMP-binding (E-value: 8e-116, bitscore:
                     382.0, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLSYAHGTGDTALLGDTIGADLARTAATWPDREALVDVPAGRRW
                     TYAEFAADVERLACALLAAGVAKGDRVGVWAVNRAEWVLVQYATARVGAIMVNVNPAYR
                     THEVEYVLRQAGVSLLFASTGHKGSDYRAMVDEVRPKLPELRRTVYFGDPGWEEFTALG
                     TGFPAERLRAREAELSCDDPINIQYTSGTTGFPKGATLSHHNILNNGFFVGELVAYTEQ
                     DRICVPVPFYHCFGMVMGNLAATSHGACIVIPAPSFEPRATLEAVQRERCTSLYGVPTM
                     FIAELNLPEFAEYDLSTLRTGIMAGSPCPVEVMKRVVAEMHMAEVSICYGMTETSPVSL
                     QTRVEDDLEHRTGTVGRVLPHLEVKVVDPATGSTLPRGGTGELCTRGYSVMLGYWEEPE
                     KTAEAVDAGRWMHTGDLALMREDGYVEIVGRIKDMIIRGGENIYPREIEEFLYAHPRIR
                     DVQVVGVPHERYGEEVLACVIPLDPADPLTLDELRAFCRDRLAHYKIPSRLRLLDAFPM
                     TVSGKVRKVELRRGHDS"
     CDS_motif       complement(29147..29209)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EV284_RS21910_0003"
                     /evalue="1.30E-03"
                     /label="NRPS-A_a8"
                     /locus_tag="EV284_RS21910"
                     /protein_end="448"
                     /protein_start="427"
                     /score="11.7"
                     /tool="antismash"
                     /translation="VGRIKDMIIRGGENIYPREIE"
     aSDomain        complement(29180..30421)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EV284_RS21910_AMP-binding.1"
                     /evalue="7.00E-111"
                     /label="EV284_RS21910_AMP-binding.1"
                     /locus_tag="EV284_RS21910"
                     /protein_end="437"
                     /protein_start="23"
                     /score="362.6"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="ARTAATWPDREALVDVPAGRRWTYAEFAADVERLACALLAAGVAK
                     GDRVGVWAVNRAEWVLVQYATARVGAIMVNVNPAYRTHEVEYVLRQAGVSLLFASTGHK
                     GSDYRAMVDEVRPKLPELRRTVYFGDPGWEEFTALGTGFPAERLRAREAELSCDDPINI
                     QYTSGTTGFPKGATLSHHNILNNGFFVGELVAYTEQDRICVPVPFYHCFGMVMGNLAAT
                     SHGACIVIPAPSFEPRATLEAVQRERCTSLYGVPTMFIAELNLPEFAEYDLSTLRTGIM
                     AGSPCPVEVMKRVVAEMHMAEVSICYGMTETSPVSLQTRVEDDLEHRTGTVGRVLPHLE
                     VKVVDPATGSTLPRGGTGELCTRGYSVMLGYWEEPEKTAEAVDAGRWMHTGDLALMRED
                     GYVEIVGRIKDMIIR"
     CDS_motif       complement(29279..29365)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EV284_RS21910_0002"
                     /evalue="3.00E-08"
                     /label="NRPS-A_a6"
                     /locus_tag="EV284_RS21910"
                     /protein_end="404"
                     /protein_start="375"
                     /score="26.0"
                     /tool="antismash"
                     /translation="PRGGTGELCTRGYSVMLGYWEEPEKTAEA"
     CDS_motif       complement(29882..29935)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EV284_RS21910_0001"
                     /evalue="1.30E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="EV284_RS21910"
                     /protein_end="203"
                     /protein_start="185"
                     /score="17.9"
                     /tool="antismash"
                     /translation="IQYTSGTTGFPKGATLSH"
ORIGIN
        1 gcccagttcg ggccgggaca gcagcttgcg caggggggac gtgcgcagca gccgctcgtc
       61 gcggggccgc tcgccgcccg gtgcggggcc ctcggtgggc cgcgtgccgg tggtggtgct
      121 catcgggtgc cccgatcggt gtacgccgcg agcgcgcccg cctggtccct ggtgatgatc
      181 tgcgggccgg tcaggaccgg cttgccgcca ccgaggacgt cgccgttgta cttgtagagc
      241 cacagcaggt cgaccgcctc gtagccctgg aggtagggct gctggtcgac ggcgaagccg
      301 agcgtgccgt ccttcagttc ggcggcgacc ttggcgttga ggtcgaaggt gtcgacctcg
      361 gccttgctgc cggcgtccgc cttggccttc accacggtgt cggcgtaggg ggcgcccagg
      421 gtgacgacgg cgtccacgtc ccggtcggcc tggagcttgg cgccgacggc ggactggacg
      481 tcgggcatgt tggtgccgtt gacgtagagc ttgctgacct tgccgtggaa ggtcttctcc
      541 acgccgtcgc agcgctgctc gtggccgacg ttgccctgct cgtgcaggac gcacagggcg
      601 ttcttgcggc cgcgcttgtt cagctcctca ccgaccgcct caccggcgat ggtctcgtcc
      661 tggccgatgt ggctgagggc gccgaacgcc ttggactggg ccgagccgga gttgaccgtg
      721 accaccggga tgccggcctt gcgggcgcgg gccacggccg ccttgagggc gtcgggcttg
      781 gccaggctga cgatgatccc gtcgaccttc ttgtcgatcg cggcgtccac gagctgggcc
      841 tgctgctggg cctcgtcgtc gtgcgagtac aggaagttga tgttgtcctt gaccgccgcc
      901 tgcttggcgc cgctctgcac gatgtcccag aaggtgtcgc cgtcgccgga gtgggtgatc
      961 atcgcgatgg tccagcgggg ggtggtcacc gctgccctgc cctgggccgt ggcggccttg
     1021 cgggcgtcct cggccttctt gccgccggtg ctgctgcagg cggtcagcga gacgcaggcg
     1081 agcagtgcga acgctcctgc cgccgtcatg cctacccggt tctgaaaccg tgccacgagg
     1141 ccgtgcccct tcttgccgtg ttctgaacgc ttgccgtgtt ctgacgcaaa cacttcagta
     1201 tcgaacacgc ggaacactcg ttacccgtcc ggggcggttt cgacagggca tttgtccgga
     1261 caatatgacg cggctgggcc tggctcaggg gcgtaccagg agctggaact cgaaggaata
     1321 ccgggccgga cggtaggtgt ggtcgccctg ctcgaccgcg cggccggtgt cgtcgaacgt
     1381 gacgcgcctc atggtgagca gcggggcgcc ctcgggctcg gcgagccgtt cggcctcggc
     1441 gagcgtggcg ccgcgggcgc cgatggactg gcgggcgctg tgcagggtga tgccggccga
     1501 gcgcatcagc cggtacaggc cggtggcctc cagccgggcg gtgtcgaggt ccagcaggcc
     1561 gagcggcagg tggttggtca ggtacgccat cggctcgccg tgcgccagcc gcagccgctc
     1621 gacgcggtgc acgtcatggc cctcggtgac gccgagcgcg gcggcgatct cggcggtggc
     1681 cgggacgacc gtgttgacca ggaccttggt ggcgggccgc tggccggccg cctccaggtc
     1741 gtcgtagagg ctgctcagtt ccagcgggcg cttgacctgg ctgtgcacga cctgggtgcc
     1801 gacaccgcgg cggcgcacca gcagtccctt gtccacgagg gactggatgg cctggcggac
     1861 ggtgggccgg gacaggccga gccgggcggc cagctcgatc tcgttgccga gcaggctgcc
     1921 gggggtgagg gcgccacgct cgatggcggc ctccagctgc tgggcgagct ggaagtacag
     1981 gggcaccggg gagcttcggt ccacgcggag gccgagcggc gcggtcgggt ccacatctgg
     2041 tttcggcacg ggctcgagcg tagtccggtg cccggatgac gggaagtcgt gaagtccggt
     2101 tgtcctgaca ttttgattga caggtgcacg ttgttccccc tcaatgtgtc ctcatgcgca
     2161 tcggggtcat cgggacgggc cgcatcgggg ccatccacgc caacacgctg agccgccacc
     2221 gggaggtcgg atcgctgatc ctgacggact ccgatccgtt acgcgcgcag gaactggcgc
     2281 accggctcgg ggagacggcg gcgccgggcg tggacgaggt cttccagtgg ggcgtggacg
     2341 cggtggtgat caccaccgcg acagcggcgc acgcggagct gatcggccgc gcggcccgct
     2401 ccgggctgcc ggtgttctgc gagaagccca tcgcgctcga cctgcccggc acgctgcacg
     2461 cgctcgccga ggtcgccgcg gcgggcaccg tgctccagat gggcttccag cggcgcttcg
     2521 acgcggggta cgtgggtgcc cgtgaggcgg tgcgctcggg ccggctcggc cggctgcaca
     2581 ccgtgcgcgc cctgacctcc gaccagtccc cgcccccgcg cgagtggctg ccgctgtccg
     2641 gcgggctgtt ccgggacacc ctgatccacg acttcgacat cctgcgctgg gtcaccggcc
     2701 gtgaagtgac cgacgtgtac gcgaccggct ccgacgccgg tccccccatg ttccgcgagg
     2761 caggcgacgt cgacaccggc gcggccctgc tcaccctgga cgacggcacc ctcgccacgg
     2821 ccaccgcgac ccgcctcaac ggcgccggtt acgacgtccg catggagctg tccggcgagc
     2881 tcgacacggt cgtcgtcggc ctggacgacc gcaccccggt cgcctccacc gaaccgaccg
     2941 gccctccccc ggccgacaga ccctggcccg gcttcctcga acgcttcggc accgcctacg
     3001 agtccgagct ctgcaccttc gtggacgtgg tccgcggcga acaccccaac ccctgcgacg
     3061 gctggcaggc gctgcaggcc ctgcgcgtcg cggaggcgtg cgagatctcc cggcgcgaac
     3121 gaagagccgt cgccctgacg gaggttcccg accggttgcg gtcctcgtac gtctgacccg
     3181 ccccggacac gaccccgccc cgcgaccccc gctgtggggg gaagggtcgc ggggcggggt
     3241 gaaccggagt ggtcagcagc cgtagtcgac gaggtcgaac gtggcgtagt ggtcggaggt
     3301 gtagtagtcc tcctgggtcc gctggccggt gacgatgcgg cgggcaccgc gggtggactc
     3361 gcccggggtg atgaccgtgt actcgtggta gtacccggag gactggccgg ggaggacgcc
     3421 ctcgcggttc tggaagacga caccgtcctg ggagtacggg tccgggccgc cctgggcgat
     3481 gaggtcgagg gtgtcgtacg cctgggacgg cagggagccg tagcagatgc tgccgaccga
     3541 ggcggtggcc gcgtccgcgg tggtggcgga gacggtgccg ccgaggagga gggcggagaa
     3601 gagggccgcc gcggcgccga tgcgagtggt gcgtgggggg aatctcatgg gttcatgatg
     3661 acgcgcgtag acgcgttcat gtcaatgagg gagatgtgga tattcccggc aggtccgatg
     3721 ggttctcccg gcgtcggcct gccccgacag gagccgttcg ggctcctgtc ggcatcccgt
     3781 cgaccggcta gaaggacccg tactcggggc ggcccgccag gtcgtacgac tggatggaga
     3841 cccccttgcc ggtgaccgtg ccgcccgcgt gcctgaagcg ggtggggacg gcgccctcca
     3901 cgaacagccg gcgcccctcg cccagcacca cggggaaggt cagcaggtgc agggtgtcga
     3961 tcaggccgag gttcaccagc gagcggacca gcgctccgct gccgtggatc tgcacctcgc
     4021 cctcggtgcg ctccttcagc gcctggacct ccttgccgag gtcgccggag agcacggtcg
     4081 tcccggccca cccagggttc tcgacggtcg cggagacgac gtacttcggc agctcgttca
     4141 gcctggccgc gaccgggttc tccgggtcgg tcaccttggg ccagtacccg gcgaagatgt
     4201 cgtaggtgtg ccggccgagc aggaaggcac cggcccggcc gaagctctcc gcgacgaagc
     4261 cgccgaagcc gtcgtcggcg tacgggaagg tccagccgcc ctggccgaag ccgccgctgg
     4321 tgtcctcgtc ggggccgccg ggagcctggt agacgccgtc gagcgagacg aagacggtgg
     4381 agacgagctt gcccatgagg tgccttcttc cgggtgcggg gtcctgctgt caacggtgca
     4441 gaccccgccc gggaccgcaa ctcatcggtc cccccggcat gcctcagccg tccagctccc
     4501 ggaaccgcgc ggccaggcgg cccgccccgg cctcggtcag cgagccgaac aggcgcagcc
     4561 gggagatccc cccgtccgga tggatgtcca cgcgcgcgtg cgtgccgacg gccgccgccg
     4621 ggagcgggaa gcggtggttg gtgtccggct ggagccgggt gcgcggcagg atctcggtcc
     4681 actccccgct ctcgccgtcc cgcaccgaca ccgacgccca gccggcgctg ttccccttca
     4741 gatacgccgt gtcgatctcc accgcgcgca ccagcgcctg ttcggtcagc cggtacgtga
     4801 tccagtcgtg gccccggtcg cgacggcgcc gggtctccca gccgtcgtcc atccgctggg
     4861 agcggcccgg ccgtacggtg ttggcggccg gggagtagaa gcggtccgag gcgtcctcgg
     4921 cgcggccgcc gttctccagc gcggccacgt cgaaggtgcc gagcgtggcc agccactccg
     4981 ggtccgggac gatctcgccg taggcgcgca gccgggcgac accaccgtcc gggtgctggt
     5041 tcagccggag atgggtgaag cgctggggcg cggagacggg gaagccgttc gccgcgtggc
     5101 cgccgaccgg ggtgaggggg acgagcgtcg tccacttcac gtcgtcgccc agcagttcct
     5161 cgggggacgg gttgccggga gccgaggtgg cctccacgga gacggcctgc gggtggttgc
     5221 cccggaagtg ggcggtgtcg acgacgatcc cccggatcac accgggcgtg ccgaggcgga
     5281 tcagcgccca gtcgtggtcg tcggcgcccg gccagggctc ctcggcgctc gggccgcgcc
     5341 ggcgccgggt ctcccagccg tccatgatct tgcccttgtg gccgaatcgg ccgggctcga
     5401 actcggcgcg gtggggcagc agcaggttct cccgctcggc gaagaactcg tcgttggcgg
     5461 cgatcaccgc ggcccccagg cgccggtcgg cgaggtcggg gtggtgggcg aaggggaagt
     5521 cggcggtgcg gtagtcggcg taggggtcgc cgccgccgta gggagccgcg tcgccggtga
     5581 agcggggcgg gtcggagggt tgctgcgccg tcacggtgat cgggggtcct ttcggcaggg
     5641 gttgcgggct tcagccggta cgggtgagca gacggccctt cggggcggtg aactcaccct
     5701 cgctgtacac ccgttggcca cgcagccagg tggacttcac caccccgtgc agcgtcttgc
     5761 cggcgtacgc ggtgaccggg ttgcggtggt ggaggcgggc cgggtcgacg gtgaaggtgc
     5821 cctccggggc gaggacggcg aagtcggcgt cacggcccgg cgcgatggcg cccttgcggt
     5881 cgaggccggc gagggccgcg gtgcgggcgg acatccaccg cacaacgtcg gtcagtcggt
     5941 gcccgcgctc gcgtgcctcg gtccagatcg cggggaggct cagctggagg ccggagatgc
     6001 cgccccaggc ggtggcgaag tccggcgtct tgaggtcggc ggtggagggc gagtggtcgg
     6061 tgacgacgca gtcgatcgtg ccgtccgcga gcgcctgcca gagcaggtcc cggttggcgg
     6121 cctcacggat gggcgggcag cacttgaact cactcgcccc gtccgggact tcctccgcgc
     6181 tcagggtgag gtagtgcggg caggtctcca cggtgacgcg gacgccttcg gcgcgggcgg
     6241 cggcgatgag cgggagggcg gctgcggagg agaggtggag cacgtgcaca cgggcgtcca
     6301 gcgtgcgcgc caaacccagc agttgggcga tggcgttcgt ctcggccgcg tgcgggcggg
     6361 aggcgaggaa gcccgcgtag gccggtccgg cgggggcgtc cgtgaggtgg gcggggtctt
     6421 cggcgtgcac gatgagcagg ccgtcgaatc cggcgatctc cgcgagcgag cgcgccagtc
     6481 gggcgctgtc caggtgcggg aactcgtcca cgccggacgg cgagagaaac gccttgaagc
     6541 cgaacacccc ggcctcgtgc agcgggcgga ggtccttgac attgccgggc agggcgccac
     6601 cccagaagcc gacgtccacg tgggtgcggc cctgtgccgc ctccctcttg acccgcagat
     6661 ggtcgaccgt ggtggtcggc ggaagggagt tcagcggcat gtcgacgagg gtggtgacac
     6721 ccccggccgc cgccgcccgc gtcgccgtcc agaacccctc ccactcggcc cggccggggt
     6781 cgttgacgtg cacgtgcgtg tcgaccagcc cgggcagcag cgcgtcgtcc cccaggtcga
     6841 cggccgggac tcccgcctcg tacggcagca cggcctcgat cgtcccgccg gcgacggtga
     6901 ccgtcgcggc ccgcaccccc tccggggtga ccacacgcgt ggaacgcaac gccagctcga
     6961 cgtcgtcgga cacccgaacc cctctcagcc gttcacgtcc aggaaacggt gttaacaccc
     7021 acgtaacgga cttcaacgtt ctgttgaagg agtctcgccg cccgctccgg cacgagtcaa
     7081 gggtgccagc cgccggggcc gcggggcctg agcggacgag ggggtgttca cgggcggtcg
     7141 gccgcagctg tccgggcccc gcggaccggt gcccccgcgc gccctgggga ggtgaccccc
     7201 gtccgtcccg caccggcgct gacgcccggc gggccggacc ccgtgacgcg gtccgcgcag
     7261 gcggccaccg gcccaggtgc ccccacccct gcccacatcc cggcatcctg gtcccatgac
     7321 gtccgaccag gccccccgcc acccccgggt caccgggctg ctgctcgccg ccggaggggg
     7381 gcggcggctc ggtgggcgac ccaaggcgct gttgcggcat gacggggcac tcctcgtaga
     7441 gcgggcggct cgtgcgctgc gggacgccgg gtgtgcccgc gtccacgtgg tgctgggagc
     7501 agggtccgaa gaggtgcgcg cggaggccga gttgagtgga tgcgtgctcg tggagaaccc
     7561 cggctggggc gagggaatgg ggtcctccct gcgggccggg cttcgctccc tcgggggtac
     7621 ggacgcgcgc ggcgctctcg tgggcctcgt cgaccagccg ggagtaggag ccgaggcgta
     7681 cgcacgggta ctggacgcct tcaccggtga gacctccctc gtgtcggccg cctacgacgg
     7741 cacgcgcggg caccccgtgc tgctgggggc cgctcactgg gccggtgtca ccgagagcgc
     7801 ccagggtgat cagggcgccc gggagtatct gcggcggcac tccgcagaga tccggctcgt
     7861 ggaatgcggg gacgtggccg aggcgtacga catcgacacc gctgccgacc tgggcaggct
     7921 gcgccccggc ggggcccatt gaggttcggc gatcaggaaa ttacgctgcc cagtccgacc
     7981 agcccgccac ggaggaagtg accgctcatg tccgcacccg cgtccccgcc ggtcgttgtc
     8041 gacgccgagc cgctcccccg gcaggaggag gtgctcaccg gcccggcgct ggacttcctc
     8101 gcggagctgc accggcggtt caccccgcgc cggaacgaac tcctggcccg ccggaccgag
     8161 cgccgcgcgg agatcgcccg caccggcacg ctggacttcc ttcccgagac ggccgcggtg
     8221 cgggccgacg actcgtggcg ggtggcaccc gcgccgcccg ccctgcggga ccgccgagtg
     8281 gagatcaccg ggccggccga ccgcaagatg acggtcaacg cgctcaactc cggcgccagg
     8341 atctggctcg ccgacttcga ggacgcctcc tcccccacct gggagaacgt ggtcctcggc
     8401 cagctcaacc tgatggacgc ctacgccggc cgcgtcgact tcaccgacgc ccgcaccggc
     8461 aagtcgtacg cgctgcgccc gcaggaggag ctggcgacgg tcgtgatgcg gccgcgcggc
     8521 tggcacctgg acgagcggca cctcgaggga gccgacggcg agcccctgcc gggcgccctg
     8581 gtcgacttcg gcctgtactt cttccacaac gccgcccgcc tgctggagct gggcaagggc
     8641 ccgtacttct acctgccgaa gaccgagtcc cacctcgaag cccgcctgtg gaacgacgtg
     8701 ttcgtgttcg cgcaggacca cctcggcatc ccgcagggca ccgtgcgggc caccgtgctg
     8761 atcgagacga tcacggccgc gtacgagatg gaggagatcc tctacgaact ccgcgaccat
     8821 gcctccgggt tgaacgcggg ccgctgggac tacctgttct ccatcgtgaa gaacttccgc
     8881 gacggcgggc cggagttcgt gctgccggac cgcaacctgg tcacgatgac ggcgccgttc
     8941 atgcgcgcgt acaccgaact cctcgtccgc acctgccaca agcggggcgc gcacgcgatc
     9001 ggcgggatgg cggccttcat cccgtcccgc aaggacgccg aggtcaacaa ggtggcgttc
     9061 gagaaggtac gggccgacaa ggaccgcgag gcggccgacg gcttcgacgg gtcctgggtg
     9121 gcccacccgg acctcgtgcc gatcgccatg gagtccttcg acaaggtgct cggcgaccgc
     9181 ccgcaccaga aggaccggct gcgcgaggac gtccacgtga aggcggccga cctgatcgac
     9241 atcgcctcgc tggacgcgaa accgacctac gccgggctgg tcaacgcggt acgggtcggc
     9301 atccggtaca tcgaggcgtg gctgcgcggg gtcggcgcgg tggccatctt cgacctgatg
     9361 gaggacgcgg ccaccgccga gatctcccgc tcgcagatct ggcagtggat caacgcgggc
     9421 gtcgagttcg agaacggcga gcgcgccacc ccggagctgg cccgccggct ggcggcggcc
     9481 gaactggagg cggtgcgggc ggagatcggc gcggaggcgt tcgcggccgg ccactggcag
     9541 gaggcgcacg acctgctgct gacggtggcg ctggacgagg agtacgccga cttcctcacc
     9601 cttccggcct accggcgcct caccggctga gcacgctcac ttgtcggagt gcccgagcga
     9661 ccgctcaggc gccacccggt cccgcaccag ccgcttgacc gccgtgggct cgggaaagcc
     9721 ctgctcacgg cggtcccaga ccggctcgcc gtccacccgg acgacgaaga cgccgccggt
     9781 gccgggcttg agcgcgaggg cctccagctc ggtctcgaag gtggtgagca actcctgcgc
     9841 cagccaggcg gcgcggggca gccagcggca ctgggtgcag tactcgatct cgacgcggtg
     9901 actcacgaag atcccttcat cccaggtgta ccgaccagtc ctgttccgcc gccgggcgtc
     9961 cgtgcaggtc ggggacgcgc ttgagccagt ccggacgccc ccgctgtgac cgctcggcgc
    10021 gggcggcctc ctcggcggcg agttccgcgc ggtcggggaa gtcggtgggc agccactcgg
    10081 cggagagccg ggcgcgggcc agcagatggt cgacgtaggc ggcgcgggcc tcgtccggcc
    10141 cggcgaaggc gggatcgtcg gtgagccagg cgtcgggcac ctcggcgagg atgccgcgca
    10201 gcagctcctc ggtgacctgg ggggccagct cggcgtcggc ggcgcgcacg tcggggccgt
    10261 actggccgag ggcgtggtgg cggaagtcgt acctacggcc ggggttcgtg gtgtcccagc
    10321 ggtggtggaa gacgagggcg gcgccgtggt cgatgagcca caggcgcggg ggcgcggtgc
    10381 cgaaggtcgg ccagaccatg aggttggagc tgtggacggt gcggtccacg ttggcggtga
    10441 gcgcgtccag ccagacgatc cggcccgcct ccagcgggtc tacggggaag ttccgggcga
    10501 tctcgggggt gaggtcgcgg gcgcccggca ggtagtccat gcccaggttg acgcccgcgc
    10561 tggcgtcgtg caggtcgcgc acctcctggt gcggctcgtc ggcggccacg gcggggtcga
    10621 agtgcacgag caccagctcg gggaagcgca gccccagggc gcgggccagc tcgccgacga
    10681 tcacctcggc gacgagtgcc ttgcggccct gcgcggagcc ggtgaacttg acgacgtagg
    10741 tccccaggtc gtcggcctcg acgacggcgg gtacggagcc gccggtgtgc aagggttcga
    10801 cgtagcgggt cgcagcgact tctctcagca tcttccaagg ctccagcgtc tattagcctc
    10861 agcttccacg cctggctccg ttgcggcgca atcctgggaa tctcccggat cagtcccggg
    10921 gagaatctgg ggagtcctgg ttggcaccgt catcctcctc gctccccggc agcctgtcga
    10981 cggcgttacg gccttgctcc cggcccccgg catgaagtga gcatagtaac caagcgtgac
    11041 agcggggggc gagtgcccga gccaccgcgc cggcgtcatc acggactccc ccgcctccag
    11101 catggtcgag gcgtacgcgt gccgcagcct gccggagaca ggtcttcgag ggcgtgttgg
    11161 gaccggatca cgcaagcgcg gcgcgcaaaa tatgacgtcg cgcgggtgag tgaatacctg
    11221 tgcccgccgg cggagatttc aacgaggcat gcggatagat tctctgccgc aataaaaagg
    11281 gtgaccttct tcttcggaca ccggctgccg cggcgtgcta ctgtcgtcct cagttgcagt
    11341 tgtggttccc gaaaacttca agtgttccgg tcggctctgt gccgccgggg agcgcttttg
    11401 tatttccggt cttttccggg cggggcaatc atcgcggcga cacggcgtcc gcacggtgcg
    11461 ggttccgatg tactgcccca aaggagaaat gacatggctg ctggtaccgt gaagtggttc
    11521 aacgcggaaa agggcttcgg cttcatcgag caggacggcg gcggcgccga cgtcttcgcc
    11581 cactactcca acatcgccgc ccagggcttc cgcgagctgt tggagggcca gaaggtgaac
    11641 ttcgacatcg cgcagggcca gaagggcccg acggccgaga acatcgttct cgcctgacgc
    11701 tgactgtcgc acacttgcag ctggggcccg catccctcgg ggtgcgggcc ccagctgcat
    11761 gcatttccca cagtgatgtg acctgtggac ggcacccagg aaatccgtag gctcgtcggc
    11821 ggatcgccct tcgggggtgc acatgcaccc cttcccagcc acagcgcagt ggacgcttca
    11881 aatgctgagc ccacaccgcg ccacttattt cagcgcttgc gaatctggcg acggacaatc
    11941 cgtgcgagtg caagctgctg ccaccccgtc ggctcattct tgcaattcct cgtgcggctc
    12001 aataccgcgg gaattccttg agatgtgccg aatcaaggaa ggttccgtat gaaccgcaca
    12061 cgtacgaacg accgcttcgc ccgcagccgt cacggcaatt ccggccgccg ggctcccgcg
    12121 gtccaggggg agttcgcgct tccccggacg acgactcccg cgcttcccgc ggtggagggt
    12181 ttcgccgatc tcgacatgcc gggggagctg ctggccgcgc tcggcgcgca gggggtgagc
    12241 gtgccgttcc cgatccaggc ggcgaccctg ccgaactccc tcgcgggccg ggacgtgctg
    12301 ggtaggggcc gcaccggttc cggcaagacg ctcgccttcg ggctcgcgct gctggcccgt
    12361 acggccgggc ggcgtgccga ggcccggcag ccgctggcgc tggtgctcgt accgacgcgt
    12421 gagctggcgc agcaggtcac cgacgcgctg gcgccgtacg cccgctcggt gaggctgcgg
    12481 ctggccacgg tggtgggcgg catgtcgatc gggcggcagg cgagcgcgct gcgcgggggc
    12541 gccgaggtgg tcgtcgccac accgggacgt ctgaaggacc tcatcgaccg gggtgagtgc
    12601 cggctggacc aggtttcggt gaccgttctg gacgaggccg accagatggc cgacatgggg
    12661 ttcatgccgc aggtcacggc cctgctcgac caggtgcgtc cggagggcca gcgcatgctg
    12721 ttctccgcga ccctggaccg caacgtcgac ctgctggtgc gccgttacct cagcgacccc
    12781 gtggtgcact cggtcgaccc ctcggccggc gcggtcacga cgatggagca ccacgtgctg
    12841 cacgtccacg gcgccgacaa gcacgccgcc accacccaga tcgccgcccg cgacggccgc
    12901 gtgatcatgt tcctcgacac caagcacgcc gtcgaccgtc tcaccgagca cctgctgaac
    12961 agcggggtcc gggccgcggc cctgcacggc gggaagtcgc agccgcagcg cacccggacc
    13021 ctggcgcagt tcaagacggg tcatgtcaac gtgctggtgg cgaccaatgt cgcggcacgc
    13081 ggcatccacg tcgacaacct cgacctcgtc gtcaacgtcg atccgcccac cgaccacaag
    13141 gactacctgc accgcggcgg ccgtaccgcc cgtgcgggcg agtccggcag cgtcgtcacc
    13201 ctggtcaccc cgagccagcg ccgcgacatg aaccgcctca tgacggacgc cggcatccgg
    13261 ccacagacca cccaggtccg ctcgggcgac gagacactga accgcatcac cggtgctcag
    13321 gccccctccg gcatcccggt cgtcatcacc gcgccggtcg ccgaccgccc caagaggcgc
    13381 agggcccccg cacgcggccg gcgccaccag gccccggcgg cccgccgcgc acccgcactc
    13441 cagtccaccg ccggtgcggc cgcctagaac cgtcttggtc agaaatccgt ccgtctgcgc
    13501 aggaggaacc ctttgatgct gggaaagttg cacactcgat ccgtgagcgt tcgccccgtg
    13561 cgaggcacgg tggccggcag cgtggacgcg gccggcccgc aggtctggta cgacatgacc
    13621 gtcgaagtgg cgctgtccgt catggccgcc gcccgtacgg agtatctcgt cgtctgcgac
    13681 gaggacggac tgtgtgtcgg cctggtcacc cagtcccagc tcaccgccgt tcgggacagc
    13741 gccggataca ccgaccggct ccgcctcgac ggcatcacag acagcaggga gccctccggc
    13801 ccaccgtggg ccacgaggga aggagccgag aaggggacgc ctcccgggcg gctcggaccc
    13861 gtgcgcgtgg tcgacgaaca cggcgacgcc ctgggcgtcc tcgccggctc ccgctgaatc
    13921 gtcggccggc ctcgtctcct ctccagcacc gccgcgactc cagcacaggt gaagccctga
    13981 gggccatggc cctcagggct tcacctgtcc cgccctcccc gcacggcgtc gcccgcgcgc
    14041 agcgggttcg gcagcggcag gtagcgggcg tccgcaccgt ccgcgccggt ccagcggagc
    14101 agcaggttgg tcttgccggg cagggcgggg gcggcgagca gggccggtat ctcggggagc
    14161 ggatggcggg acagctcggc gcggagggcc ggccaggggt cgaggccggg gtgggcctcg
    14221 gccagggcgg cggcgatctc gccgaggtgg ttgacgagca ggcagtacac cagccgctcc
    14281 cacccggcct cccggcccac gtcggacagc agcttgacgc cctcggcgtc ccggaacagg
    14341 gcctgcacgg gcattccggc ggcgtcgacg gcgaccaggg tgttctgcag gtgcgcctcc
    14401 acgacgacgc cgtactcgtc gaaggcgcgg agcgcgggcg ggacgacctg gcggagatac
    14461 gcggcccacc aggcgtccgg gtcgggggcg gcggcgagcg ggctgccgtc gaagccctcg
    14521 gccagcccgg ccgcgagcaa cggcgtggcg ccgggcagga ggtggccgcg caggccgtcg
    14581 cggaccagga cggcgagttc ctcgaaggcg aacgcggcgg tgcggtagcc ccggtcgctg
    14641 agccaggccg cgggcggtcc catcgcggcg aaggcctcgc gggccgcggt gtcgctgcgg
    14701 tcgagtctct gcaggtcgtg gcgccacagc cggcggatgt cgttggtgat gcggacgtcg
    14761 aggctgaact tgaggaacag gtcgcggccg ggctcgtaca cggtgcgcac ggctgccgtc
    14821 ggccggaccg cggactcggt ggtgccgagc cggatcaggc gccggtcggc gaaggcgggg
    14881 gcgaggcctg gggcgagcag gtcgagctgc caggggtggg cgggcagcag ccggtagccg
    14941 ggcggggcgg tgccgagggc gtccagggcg cgggtgtcac cctcttcggc gacctggtcc
    15001 tcgcggacgc cgagcagcac cagcgggaac cgggcgtgcg cctcgggggc gtagggcagc
    15061 caggccgcga ccgggccgcc gccgcgcgcc ttgggcgccg ggtggtgcgg atggccggtg
    15121 atcagcgact gctcggagcg cagatacggg tcctcggggg cgacggcgcg ggcgcgggcc
    15181 gcgagcaggg cggcgacggt gtcgcggctg tccagcatct cggcgggcag gtcgtctccc
    15241 ggcagcccgg tgtgggcgcg cagttcctcc gcgaccagtt tgaccagttc ggcgtggctc
    15301 agcggctgcc aggcaccgtc cgcgcgtact tcgggctcgg cgggacggcg gccggggcgc
    15361 acccgcagca gccggccggt gccgggcagc cggtacacgg gccggtcccc gcgctccggg
    15421 accggccggg ccacctcgcg cagcaggcag ttcagcagcg gcgccgaggc gtaggcgtcg
    15481 gcgcgccgtg cggcgtcggt cggggggttg aggtccacgc gttccactcg ttctcgtcgt
    15541 gctgtggccg gtccgggggg ccgaccgtgc caggtaagtc tgcggtatcc gacaatcgtg
    15601 ccctgagctg ccagtctccg aggagccgac cgtgtaccac tcccccaccg ccgaggccga
    15661 ggtcgccgag gagctggccg ccgtacggcc cgccctgcgc gaccgttgca cggccgcgct
    15721 gccgggagcc cgcgcggcgg tgctgaccag gctgtggcgg gcgctggcgc acgaaccgct
    15781 tccgtgggtc gcctcccgga cgccgggggc acacggactg acggtacggc tggcggacgg
    15841 ccgcgcgctg cacggcccgc actcggaccc gtacgcgacc ggtgaccgcg tccacgaggt
    15901 ccggctcggc cgggagcggt acgcggaccc cgcgcggctg atgacggacc tcgcggtgcc
    15961 gcacgcggcc gcgttcgccg ccgagctggc gaacagcgtg gcctcgctgg cgctgtcccg
    16021 cgccgacgcg gcggagccgg gggccgggtg gccggagcgg gactgggagt gggagcagcg
    16081 ggtggtggac ggtcacccct tccaccccaa ctgccgttcc cggccgggct tctcggtggc
    16141 cgaccagttg gcgtacgggc ccgagcaccg gccggtggtg gagctgggca cggtggcggt
    16201 gccggcgggc gagtgcctgg tgtcgggcga gtggccggcc ggactccgct ccggagacga
    16261 cctgttgctg ccggtgcatc cctggcaggc ggcgcatgtg ctcaagcgga gcaccgagcc
    16321 gtggcgtccg gcgcatccgc tgatgtcgct gcgcacgctg gcgctgcccg gcggacccca
    16381 tgtgaagacc tcgctgagcg cccggctgac ctcctcggtg cgggacatct ccgcctactc
    16441 ggtacgggcg tcggcagacc tgtcggtgct ggcggcggag ctggtcgggc ggatggacgg
    16501 gctgctggag gtcacgcaca ccatcggggc ggccacggcc cactcgccgg atctcgcggt
    16561 gctgctgcgc gagtcgcccg aggagtacct ggctcagggc gagcgggtgc tgccggtggc
    16621 cgcgctggcc accacggcgt tgccccggtc gccgggctgg ctggccgcgt tcacccggct
    16681 cacgctcacg gccggcctgc gcctgctgga cctgggggtc gcgctggagg cgcacggcca
    16741 gaacctcctg gtggtgctcg cgccggacga caccccgctg cggctgatct accgcgacct
    16801 ggccgacata cgcgtcagcc cggcccgcct cgcccgacac ggcatatcca gcggcgagtt
    16861 gacgggacgc ctgatcacgg acgacgaact cgccctgcgg cgcaagctgt tcggatcgat
    16921 ggtcgggggc gcgctcgcgg cgaccgccgg ttcgggcccg gcgctgggtg ccgcgctgcg
    16981 ggccgcgctg ccggatctgc cccgtacgcc cgacctggcg gcgctgtgtg aaaatccgct
    17041 gcccgtcaag gcgttgaccc tgatgaggct gtctccggag acccccggcg acctgtggac
    17101 ggagcttccc agcccgttcg ttttggagcg cgacacctac gatcaataag atccgccgat
    17161 gatcagaaga caacggctgg cggcgggcgt ctgcgccctg ctcgccgccc tggcggccgg
    17221 gatcgcgtgt cccggcgggg ccgcagcgga cgagaccgag ccgcagcccg ctccgaaggt
    17281 cgaactcgtc ctggatgtca gcggttccat gcgcacgcgg gacatcgacg gcggaacccg
    17341 gatggcggcg gccaagcagg cgttcaacga ggtgctcgac gcgacgcccg aggaggtgca
    17401 gctgggcatc cgcacgctgg gcgccaacta ccgcggcaac gaccgcaggg agggctgcaa
    17461 ggacaccgag cggctctatc cggtgggccc gctggaccgc accgaggcga agaccgccgt
    17521 ggccaccctg gcacccaccg gctggacccc catcggcccg gcgctgctga aggcggcaga
    17581 cgacttcggg accggtgacg gcacccgccg catcgtcctg atcagcgacg gcgaggacac
    17641 ctgccagccc ctcgacccgt gtgaggtggc ccgcgagata gccgccaagg gcatcggcct
    17701 gaccatcgac accctgggcc tggtgccgga cgccaagacc cgcgaccagt tgagctgcat
    17761 cgcggacgcc acgggcggca cgtacacctc cgtgcagcac aaggaggaac tgacggaccg
    17821 ggtcggccag ttggtcgagc gggccgccga tccggtggtg acgccggtgg ccaccgaggg
    17881 caccgacgcg tgcgccgggg cgcccgccct gaagtccggt ctgtacacgg accgcgagga
    17941 gttcggcaag cagcgctggt acaaggtcga cgtccggccc ggccaggagc tgcgcgcctc
    18001 ggtgagcgtc gccgacgacc gcgccacgaa ccccaactac ggtgtgctgc tgcgggcggt
    18061 gacccagcag ggccgcgaga tcgtacgcgg cgagggcgcc ggcaccggcc gtaccgacgc
    18121 gatctccacc ggactgcgct atcccaagcc cgagtccgac gatgacgacg cgaccccgga
    18181 gaccgtgtgc ctccaggtga cccactcctt ctcggccggc gccggtgtca agaccacgcc
    18241 gggcatgccg ctggagctga cggtcgacgt ggtcgacggg ccctccgcct cctccgacgt
    18301 ggcctccttc ggcctcggcc ggggctggtg gctgctggcc gcgctggtgc tgaccggttt
    18361 cgtcgcgggt ctgctgtggg gctggctgtc ccgctggcgg gtcgcggtct ggaggacgaa
    18421 ctgatgcgtg cgatacgcgt gttgagcgcg gccctgctga cgctgggcct ggccgccgcc
    18481 cccgccgcgg ccgactcctc cccctccccg agcgcctcgg cggacggcaa ggcccccaca
    18541 caggcgggca cgtccttccg tacggcggcc gagatggacc aggggcagac cgccaccgcc
    18601 tccgcgtcca ccggtgacta cctgtactgg tcgttcccgg ccgacaccgg gcagcgcccg
    18661 accgtcaagg ccacggtgaa gctgccggac gcgcatgccg cgcagacctg gcagctcgac
    18721 gtctacgacg gtctgcgccg ccaccagtcc tgccagtacg gcgcggccac ccgcaccgcc
    18781 gggcagggca cggccaccgt cgacctgacc tgtgtgctgc gcacggtgcg cgcctggtcc
    18841 gagccgtggg ccaacgaccc gctgcccggc acctactacg tccggctgac ggtgctgaac
    18901 ctcggctccg ccgacctcgg cctgccggta cgggcggaag tccgcgcgga ctccaggaac
    18961 atcggcggcg ccgcggccgt ggacggctcg ctgggcaagc cgctcgtccc cggtatcgcg
    19021 gtcgagcccg aggcggagaa ggacggttcg aagtcggccg tgctctccgc gatcgagccg
    19081 gatgacggct ggtcctcgca ctggtggtcg agccgctggg tatggacggc cgccggcggt
    19141 gtgctggccg cgctcgcggg catcggcggt tacgcgctga cccggggccg gggccgcccg
    19201 gcgtacgtcc caccgggcgc ctgacccgga cgaaggcccg ccgacacggc gggccttcgt
    19261 cacttcagca gcgccttggc gagggtcccg ccaccggtca ccgtgacccg ccccgcccgc
    19321 accgcgtccg cgatccccgt ctcgccccgg cagacctcca cgcaggtcgc cgcgtccatc
    19381 accagccggg cgtcggcggc caccggcgcc ggtccgtgcc cgtacgccgg gccgtcctcc
    19441 gtgccgacgt acagatggaa ctccccgtcc tccgtgctga cttcggccac cccggccccc
    19501 agctccgccg cgttcagcac cgccagcagc ggcagcgccg accagtgggc gcgtaccgcg
    19561 tcggtgggcc gcggttccgc cagctcgggg cttccccact cccccagggc gtgcagcacg
    19621 ggcagcaagc cccggccgcg cggggtgagt tcgtacacgt aggcggcgcc gggcgggggc
    19681 agcctccgcc gggcggtgat cgcgtcgcgc tccatgtcct tcagccggga ggcgagtacg
    19741 tccgtgctca cgccggggag gtcggcgtgc aggtcggtgt agcggcgggg tccggccagc
    19801 aactcccgga cgatcagcag ggtccagcgg tccccgacga ggtcgagggc gcgggccgcg
    19861 gagcagtact ggtcgtagcg tcggcgaggt ggcatgcgac gcagtctaga catgttgttg
    19921 gactttccaa gctccaactt ggtaaaacca agcaacacca gttaccggag gggtcgcggc
    19981 atggagttcc ggcagtcgaa caagctcagc gaggtctgct acgagatccg cggtccggtg
    20041 atccagcacg cggacgcgct ggaggaagcc gggcacagcg tgctgcgcct gaacaccggc
    20101 aacccggcgc tcttcggatt cgaggcgccg gaggagatca cccaggacat gatccggatg
    20161 ctcccccgcg cccacggcta caccgactcg cgcggtgtcc tctcggcccg ccgggcggtg
    20221 gcccagcgct accagaccct cggccttcag gtggacgtcg acgacgtgtt cctgggcaac
    20281 ggcgtctccg agctggtctc catggccgta caggcgctgg tggaggacgg cgacgaagtg
    20341 ctcatcccgg ccccggactt cccgctgtgg acggcggtca ccacgctggc cggaggccga
    20401 gccgttcatt acctgtgcga cgagcagtcc gactgggcgc ccgacctggc cgacatggcg
    20461 tcgaagatca ccgaccgcac caaggccgtg gtgatcatca accccaacaa cccgaccggc
    20521 gcggtgtacc cgaaggagat cgtcgagggc atcctcgacc tggcccgccg ccacgggctg
    20581 atggtgttcg cggacgagat ctacgaccag atcctctacg acggggccgt ccaccactcg
    20641 gccgccgccc tcgcccccga cctggtcgtc ctcaccttct gcggcctctc caagacctac
    20701 cgggtggcgg ggttccgctc cggctggctg gtggtcaccg ggcccaagca gcacgcgaag
    20761 agctatctgg agggcctgac catgctggcc tccatgcggc tgtgccccaa cgcgcccgcc
    20821 cagtacgcca tccaggccgc gctcggcggc cgccagtcca tccacgaact caccgcgccc
    20881 ggcggccgcc tgtacgagca gcggaacgtg gcctgggaga agctcaacga gatccccggc
    20941 gtctcctgcg tccgccccaa gggcgcgctg tacgccttcc cgcgcctgga ccccaaggtg
    21001 cacaagatcc acgacgacga gaagttcgtc ctcgacctgc tgctccgcga gaagatccag
    21061 gtcgtccagg gcaccggctt caactggccc gcccccgacc atttccgcat cctcaccctc
    21121 ccctacgcgg acgacctgga ggcggcgatc ggccggatcg gccgcttcct gagcgggtac
    21181 cggcagtagc tcccgagggg gctgtcagtg cccggccgta cgcttcgggg accagcagcg
    21241 gaccggaagg gagcaccgcg atggcacgac cgcccaccgc cgcccagcgg cgcgtcgtcg
    21301 agggcgccga ccccggaacg ggacggctgc ggggcacggc cgcccagctc gccgcgctgg
    21361 tccggctcgg tctcgccttc cgccaccccc ggccgcccca cgaccacttc ctgaccccgg
    21421 ccggccaccg cctgcgcgag gccgggccgg agcccgcttc cgcccccgcg cccgccgccc
    21481 ccgccggtgt cttcgccgcg cgggtcggcg gcgccgagga ggcggcgccc gggccctccc
    21541 ggatgcgcga ggtgcgtgac gcctggcagg gcctcatgga gctgcgccgc atgaccaacc
    21601 ccgacagcgc caccgaccgc ccctgcggct gggaacgcac ccacctggtc cgcgccgccg
    21661 ccctcgccct ggaggcggcc ggccacgggc cggagcacgc cggcaccccc ggctaccgcg
    21721 tccgcgcgac cccgcagccc gaggcggtcg cggtgtacgg cccggcgctc cagccgtacg
    21781 cggccacact ggaggcggcg ggctggcagt gcggcgagta caccgaggcc cgcacccgga
    21841 cccgccacct cctggcgtcc ccgcgccggg tatgaccccc ggtcagctcc gcgcgagccg
    21901 ccgcgcctgc tcgcgggtgg tccgggcgat cgcgtcctcg tccacgtgca gcagccgccc
    21961 gtccgccacg atctgccggc cgcccacgaa ggaggcggtg accggggccg gagcgccgag
    22021 caccagggcc gccaccgggt cggcgatgga ggcgtgggcc agggtgtcca tgcgccagag
    22081 gaccaggtcg gcgagcttgc cgggctccag ggagccggtc tcggccgccc ggcccaggac
    22141 ctgggcgccg ccgtaggtgc cgaggcggag ggcctggcgg gtggtgaggg cggcttcgcg
    22201 gtgcgggccg aggcggttga cgaggagggc gttgcgcagc tcggtgtgga gttcgccgga
    22261 ctcgttggag gccgtgccgt ccacgcccag gccgaccggg acgcccgccg ccagcaggtc
    22321 cggcacgcgc gcgatccccg ccgccagccg ggcgttggag gacgggcagt gggcgacgcc
    22381 cgtaccggtg cgggcgaagg cggtgatgtc ggagtcgttc atgtgcacgc agtgcgccat
    22441 ccacacgtcc tcgcccagcc agccggtgga ctcgaagtac tcggtcgggc ccatcccgaa
    22501 cagctcgtgg cagaacttct cctcctccac cgtctccgag ccatgggtgt gcagccgcac
    22561 ccccagccgc cgcgccagct ccgcgccctg cttcatcagt tcggtggaga cggagaaggg
    22621 cgagcagggc gcgaccgcga cctgggtcag cgcgccgaag gaggggtcgt ggtgttccgc
    22681 cacggtggcc tcggtggcgg ccagcgcctc gtccaggctc tccaccgcga agtccggcgg
    22741 cagcccgccg tccgactccc cccggtccat cgagccacgg gccagggtga agcggacgcc
    22801 ggtgtcgcgg gcggcgcgca cgatcgcgcc ggacaggtcg ccggtaccgc gcgggtagac
    22861 gtagtggtgg tccatggcgg tggtgacccc gccccgggcc atcatcgcca gcgagccccg
    22921 cgcgcccgcg gacaccatgt cctcgtcgat gcgcgcccac gtcgggtaga gggcggtcag
    22981 ccactcgaag aggttgtggt cggtggccag accacgggtg agccactggt agaagtggtg
    23041 gtgggtgttg accaggccgg gggtggccag atgcccgccg gcgtcgatcc ggcggatgac
    23101 cccggtgagc cccgcggggg ccgggcccgc gccgaccgac tcgatccggt caccggcgag
    23161 gacgaggtgc cccgtggcgt actcggtgtc gtccgcgtcc acggtggcga tcgcgcagtt
    23221 ctcgatgacg atgcgctcgg ctggtgccac ggttcgtcct tcgctctcag aggttggtga
    23281 ggtccaccgg gatcgccgcc tcgcggccct cgcggaggac ggtcgcctcg atcaggccgt
    23341 agggccggtc ggcggcgagg tacacctcgt tgtcgttggt cagcccgaag ggcgtgaggt
    23401 cggccaggaa gtggtgcttg ttcggcaggg agagccggat ctcgtcgatc tcggcacgct
    23461 ccccgatcac ccgcgcgccc atctcgtaca gggtctgctg gagcgagtac gagtaggttc
    23521 cggcgaaggc ttccagcagg tggcgccggg ccccggcgta ggaggcgtcc cagtcgggcg
    23581 cgtcgccctc gccggtccag ccgtaccgcc agcgggcgtt cacctcggtg gccagcacgc
    23641 ggttgtacgc ctcggggagg gtggtgtact cgtccttggc atagccccag aactcggagt
    23701 cggtggagtt gagcaccacc aggtccccca gtccggagac cacctgccag gtggtgccgt
    23761 cgtggaagac ctgggtgagc cgcacctcct ggcccgtgcg gacgaaggag tgcccgccgt
    23821 cttccgcgcc gatccggtcc caggcgtact cctcgatccg gatgcgggcc gtgcggatcg
    23881 cctcctggga ggtgacgaag tgccgggcga ggtggatgcc gaactgctcg gcggactcga
    23941 tgccgtaccg cttggcgaag gcgtacaccg tgttcttggt ggtgtcggtc ggcaggacgt
    24001 gggcgttgga gccggagtag tggacgtcgt ccatgtcgcc gccgagggtg acggagacgt
    24061 tgaggtcctt gatgtggtgg gtggcgccgt cgcgcgtgat ccggacgacg cggttttcgg
    24121 ccttgccgta ctggttctgc cccaggatcg cgggcccgga cgggcgggac gtttctgcca
    24181 tgaaagctag ctccctcggt atacggagta gccgaacggg ctgagcagca gcgggacgtg
    24241 gtagtgctcc ccggcccgta cggcgaaggt gacggtcacc tcggggaaga acgcgtcccc
    24301 tcgctcccgc agatacggct ccacggcgaa gtcgagccgg acccgcgcgg tgtccccggg
    24361 cggggcgggc agatcccggc agcggccgtc ggcgtcggtg gtcccctcgc cgagcgggcg
    24421 ccagtcggcg ccggacgcgg tgcgggccga gaggcggaca gtgacgcccg gcgcgggtcg
    24481 gccgagcgag gtgtccagga tgtgggtgga gacggaggcg gtggtggtca tggtgcgggc
    24541 gtccttcagg cgacgagtcg ggccaggcgg atgcggttga tcctgcccag ttcggcgcgg
    24601 gcgatctccc gttcccgctc cggtgtgttg ccgagccgct ccgtcagggc gtcgcgcatc
    24661 tgctcgccgg tcaggccggt ggcgcagatc aggaagacat ggccgaagcg gtcctggtag
    24721 gcgaggttca gttcgagcat ctcggcgcgc agggcgccgg aggcgtccgc catgccgcgc
    24781 tgctcccgcg cggaggcggg atcaccgggc tcggggcggc cgatcggggg gtggcccgcc
    24841 atcgcctcgg ccaggtcgcc ggcgccgagt ccggcgaggg ccgcgtcggc ggcgaggtac
    24901 aggtcgtccg gtgtggcgta cgggcgggcg accaggagca ggcggcccca ggcggtggag
    24961 gcgcacacct cgtgcagggc ggcgagcgcg gcgtcctccc cgagggcgtt gaaccgggcc
    25021 aggcccaggg gggtggcggg cgatgtcacg ggcgcctccg tggccgcgag ggccgtcgtg
    25081 ccggacgggg tgccgtcagc taacgcctca ccgcgacggc acgtcaacac tttgttgaaa
    25141 attctgggtt accgggcggg ctcagcggcc cttctcccgg ttgaggtagt tgtagatggt
    25201 gaagcggctg acgccaagcg cccccgccac ggtctccacg ccgtgccgca cggcgaaggc
    25261 gccccgcgcc tccagcgtcc ggacgattcc ctgcttggcc ttgcggtcca gctcggccag
    25321 cggccgcccc tcgcggcgct ccagcgcggt gaggatgtgg tcgagggact ccgcgagctg
    25381 cggcagccgt acggcgacga cctcggcacc ctcccaggcc agcaccacgt cgtccgggcc
    25441 ggcctcgccc ggcgggagga gttcaccgcc catggcgtcc acgagggggc gcacggcggc
    25501 gacgaagggc tcctcggcgg tcacctaccg tcctccccga ccacgttgac ctggagggat
    25561 atccgggtcg ccccggcctg aaggctccgc cgcagcagcg cgtccacggc actgagcacc
    25621 ccgtccgcac cgccctcggc catggtgccg aacggcccca cgtccaccgt gtccagcccg
    25681 ccgccctcca cgacctcgcg ggccgccacc gcgtgcgcgg gcgggacgtc caggtcgaag
    25741 ggttcggtgg tgaactccac tcgcagtctc aactctgccc ccaggtctcg gtcgtacgac
    25801 cctagtggac gcccctgcga accggccccg cgcggcagcg gccgcgcggg gccggtgagg
    25861 tcactcgggc aggtgccccg tcgcccagcc ggtgtcgggg gcggtggtca gggcgaagtc
    25921 cagcctgccg ccgtcgagcg cctcgcccgg ggtgagccag gagcggttca ccgggtgccc
    25981 ctcgcggtgt acggcggcgg tgtagacatg ggtgtcgtcg gcctcggggg cggtgatgac
    26041 gaggtcggcc cggcccggcc ggaccagggt cgccttcggg aacaccgggg cgccgagcag
    26101 caggacggcg ctgccggggg tctgcgggta gaggccgagg gcggagaaga cgtaccaggc
    26161 ggacatggtg ccgaggtcgt cgttgcccgg gaggccggcg gggccggtgg cgtagacggt
    26221 gtcgaggatc cggcgcaccg tcgcctgggt cttccacggc tgcccgagcg cgttgtagag
    26281 ccagggggcg tggatgccgg gctcgttcgt ggggtcgtag cgcagggggt cgccgccgcg
    26341 tacggaccag gagccgtccg ggttgtggaa gaagccgtcg agccgggtcg cggccgcgtt
    26401 ccggccgccc atcgcgccgg cgagcccctg gacgtcgtgc ggcaccatcc aggtgtaggt
    26461 ggcgctggtg ccctgcgcga acccgaggtc gctcgcgggg ttgaagggcg tgatccaggt
    26521 gccgtcgagc ttgcgggcct ggacgtggcc tgtggcgggg ttgaagacgt tgcgccagta
    26581 ggcggcgcgg tcggtgaaga ccttcgcgtc cgcgtcccgg ccgagcccgc gcgcccactg
    26641 tgccagggag aagtccgcca ccgcgtcctc cagggtctcc gccgcgcctc cccagcagtg
    26701 acaggcgtcc tggggtgcgt agtgcgagac caagtactgg gccaggttgg gacgttgccc
    26761 ctcgcactgg ccggggcagc ccgcgtcgga caggtcgtcc ggcgtcggga cggtggcctg
    26821 gcggaccagg gaggtgtagg cgccccggta gtcgaagttc cggaccccca tggcgtagaa
    26881 ggtggccagg gtggcggcgg acgggtcgcc ggtcatcacg tgggtggcgc cgctgatgtg
    26941 cacccagcgg tcccagaccc cgccgttctg ccgggcgaag ttgtagagcg actgcgcgaa
    27001 gtcgcccgcc accgtgggcc ggagcagcgc gagcaactgg atctgcgccc ggtactggtc
    27061 ccagccggag aagttgctgt actgcgcccg ctgcccgcgc gccgtccggt gcacggcctg
    27121 gtccatgccc cggtagcgcc cgtcggtgtc gctgatcagg ttgggctgca tcagggagtg
    27181 gtagagcgcg gtgtagaacg cggtacgccg ggccggactg ccgccctcgg cgcgtacggt
    27241 gctcagctcg cggtcccaga cccgcgcccc ggccgcggcc acgtcggcga cgcccgcccg
    27301 tgccgggatc tcgtggcgga ggttggcctc ggcgcccgcg aggctgacgt aggagatgcc
    27361 gagccgcatg tggacatcgt tgtcagacgc cgtgtcgaag ccgacccagc cgccggagcc
    27421 gcgtccggcg cggtcggcgc ccgtggcgta gccctcgccg ccggaggccg tggtggagcc
    27481 gggcgacaga gtgccgtcgt gccaggtgcc ggtggtggcg aaggcccggt cgaaggtggc
    27541 gctgaagtgg agccggtagt agctcttgcg gttgttggtc ccgccgttgg cgcggcggcc
    27601 gcagaacgcg ccggtcagca cccagccggt gaccttgcgg tgggcggcgt cgatgtcgat
    27661 gtgcgcgtcc tcgctgccgt tgagcgagtt ggagacccgg aacagcaggc tcgccgggcg
    27721 gcccgccggg aaggcgaagt cggcgacccc ggcccgccgg ctcaccgcga ggtcggcgga
    27781 ggcgccggag gcgaggccga gggtgtagcg gccgggtacg gccttctcgt cggcgtggga
    27841 gaagttcgcc gcgtagacgg cgtccttggt gtcggcggac ggggaggacg tgatgtcgcc
    27901 cgtgaacggc atgatcggga tgtccccggc cgcgccgggg tggcagccgg cgccgttgac
    27961 atgggtgagg ctgagaccgc gtatccgggt ggtgttgtag gcatacccgt tggcggcgcc
    28021 ggtgctggtc tggtccccgg cggtactggt gggcgaccag gcgatcatgc cctggggcag
    28081 ggtggcgccc gggaaggtgt tgccgccgtt cgcggagccg atcagcgggt ccaccagcga
    28141 cgacagcggc tccggcccgc tcgccgcgac ggccgggaag ggggccgcca cggcgagcgc
    28201 ggtggtgacg gccgtgacgg ccgtcctggt gccgagccgt ctcacggcgc gtaggagagc
    28261 gtggcgcatg cgtcgggtct gcctttccgt gggaagcatg gggcgccgcg aggctagaag
    28321 cccggccggt gccggggaag agggcggggg gcggcggccg gtgaatcctg ggcgaattct
    28381 cgggccccct cgtcgagtag cggcgccgcc cgatccgcag gacgctgaag ccatggccga
    28441 tccgacgcgg tatccgcaca tcgtggtcca ccccccggcg ctcgacggct cccgccgggt
    28501 caccgagggt gaggtcaccc tcgggctcgc ctcccacctg gacgacgtga tcgagatcct
    28561 ccgcctggcc gacctcgacc gcatcgaggt cgaggagagc gacctgatcg actggatcgg
    28621 cggcggcccc gacgactggc ccgggctgtc ggagcacgag ctgtgaggca gcgggtggcc
    28681 cgaggcgtga ggacgcccgg ctccgggggc caacctcaaa tcaacctctg aagaccgccc
    28741 gaaaggcttc aaccgccgtc gggagagggc agattgaggg tgcgaggtcc cgccgggacg
    28801 ggggtggcgg gccttgcgga cgggggactt gtggggcgcg gttccggccg gaaggccacg
    28861 ggggcgaccg cgccccgcag gcatgtcagg agtcgtgacc gcggcgcagt tccaccttgc
    28921 ggaccttgcc cgacaccgtc atcgggaagg cgtcgaggag ccggagccgg ctcgggatct
    28981 tgtagtgggc cagccggtcc cggcagaagg cgcgcagttc gtccagcgtg agcgggtcgg
    29041 ccgggtcgag cgggatgaca cacgcgagga cctcctcgcc gtaccgctcg tgcggcacgc
    29101 cgaccacctg gacgtcccgg atcctggggt gggcgtagag gaactcctcg atctcgcgcg
    29161 ggtagatgtt ctcgccaccc cggatgatca tgtccttgat gcggccgacg atctccacat
    29221 agccgtcctc gcgcatcagg gcgaggtcgc cggtgtgcat ccagcggccg gcgtcgacgg
    29281 cctcggcggt cttctcgggc tcctcccagt agccgagcat gacgctgtag ccacgggtgc
    29341 acagctcgcc cgtcccgcca cggggcaggg tgctgccggt ggccgggtcg accaccttga
    29401 cctccaggtg cggcagcacg cggccgaccg tgccggtgcg gtgctccagg tcgtcctcga
    29461 cacgggtctg cagggagacc ggggaggtct cggtcatgcc gtagcagatg gacacctcgg
    29521 ccatgtgcat ctcggcgacc acccgcttca tcacctccac cgggcagggc gagcccgcca
    29581 tgatgccggt gcgcagggtg gagaggtcgt actccgcgaa ctcggggagg ttcagctcgg
    29641 cgatgaacat cgtgggcacc ccgtacagcg aggtgcaccg ctcccgctgg accgcctcca
    29701 gggtggccct gggctcgaag gacggggccg ggatgacgat gcaggcgccg tgggaggtgg
    29761 ccgcgaggtt gcccatcacc atgccgaagc agtggtagaa ggggacgggc acgcagatcc
    29821 ggtcctgctc ggtgtaggcg accagctccc ccacgaagaa gccgttgttg aggatgttgt
    29881 ggtgggagag ggtggcaccc ttcgggaaac cggtggtgcc cgaggtgtac tggatgttga
    29941 tcgggtcgtc gcaggacaac tcggcttccc gcgcccgcag tcgctcggcg gggaacccgg
    30001 tgccgagcgc ggtgaactcc tcccagcccg ggtccccgaa gtacaccgtc cgccgcagtt
    30061 ccggcagctt cgggcgcact tcgtccacca tggcccggta gtcgctgccc ttgtgcccgg
    30121 tggaggcgaa cagcagggag acccctgcct gccggaggac gtactccacc tcgtgggtgc
    30181 gataggcggg gttgacgttg accatgatcg cgccgacccg cgcggtggcg tactggacga
    30241 gcacccactc cgcccggttg accgcccaga cgcccacccg gtcgcccttg gccaccccgg
    30301 cggcgagcag cgcgcaggcc agccgctcga cgtcggcggc gaactcggcg taggtccacc
    30361 ggcgcccggc gggcacgtcg accagggcct cccggtccgg ccaggtggcc gccgtgcggg
    30421 cgaggtcggc gccgatggtg tcaccgagca gggcggtgtc gccggtgccg tgcgcgtagg
    30481 agagggtcac cggaagtcct cctcgcggta ctcgtccgcc gagcccgcgg ccgtggcctc
    30541 gcgcagctcg atgcggcgga tcttgccgga cacggtcttg ggcagcggcc cgaactccag
    30601 cctgcgcagc cgcttgtagg gcgcgagcac ctcacgggag tgctcgaaga gcgccttcgc
    30661 ggtaccgggt ccgggctccc agccctcggc gagcaccacg tacgccttcg gcaccgagag
    30721 ccggaggtcg tcgggcgcgg gcaccaccgc ggcctcggcc accgcctcgt gctccagcag
    30781 cgcgctctcc agctcgaagg ggctgatctt gtagtcactg gccttgaaga catcgtctcc
    30841 ccgacccgtg tagtagacgt acccgtcggc gtcgcgggag ccgatgtcgc cggtgcggta
    30901 gtagccgtcg gccatcgcct cggcggtgcg cccggggtcg ccgtggtagc cggtcatcag
    30961 gccgacgggg cgcgcggaga ggtcgagcgc gatctcgccc tcggtggcgc cgggcgcgcc
    31021 ggtgaccggg tcgaggagtt cgacgcggta gccggggctg ggccggccca tggagcccga
    31081 acgcagctcc tggccggggc tgttggagat ctgtacggcc gtctcggtct gcccgaaccc
    31141 gtcccgtac
//
