LOCUS       NZ_SHKU01000004        20462 bp    DNA     linear   CON 27-MAY-2024
DEFINITION  Streptomyces sp. BK022 Ga0307664_104, whole genome shotgun sequence.
ACCESSION   NZ_SHKU01000004
VERSION     NZ_SHKU01000004.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. BK022
  ORGANISM  Streptomyces sp. BK022
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 951417)
  AUTHORS   Kalluri,U.
  TITLE     Understanding the reciprocal impacts of modified plant cell wall and
            associated microbiome
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 951417)
  AUTHORS   Kalluri,U., Huntemann,M., Clum,A., Pillay,M., Palaniappan,K.,
            Varghese,N., Mikhailova,N., Stamatis,D., Reddy,T., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-FEB-2019) Prokaryotic Super Group, DOE Joint Genome
            Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.12.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 215.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004217355.1-RS_2024_05_27
            Annotation Date                   :: 05/27/2024 02:58:00
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,482
            CDSs (total)                      :: 6,401
            Genes (coding)                    :: 6,280
            CDSs (with protein)               :: 6,280
            Genes (RNA)                       :: 81
            rRNAs                             :: 5, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 16S)
            partial rRNAs                     :: 3, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 121
            CDSs (without protein)            :: 121
            Pseudo Genes (ambiguous residues) :: 0 of 121
            Pseudo Genes (frameshifted)       :: 49 of 121
            Pseudo Genes (incomplete)         :: 92 of 121
            Pseudo Genes (internal stop)      :: 16 of 121
            Pseudo Genes (multiple problems)  :: 29 of 121
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:05:10
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 525399
            Orig. end                         :: 545861
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            SHKU01000004.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20462
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="phenazine"
                     /region_number="2"
                     /rules="phzB"
                     /tool="antismash"
     cand_cluster    1..20462
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="phzB"
                     /kind="single"
                     /product="phenazine"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20462
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:10462](+)"
                     /cutoff="20000"
                     /detection_rule="phzB"
                     /neighbourhood="10000"
                     /product="phenazine"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10462
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="phzB"
                     /neighbourhood="10000"
                     /product="phenazine"
                     /protocluster_number="1"
     gene            complement(955..2523)
                     /locus_tag="EV284_RS19155"
                     /old_locus_tag="EV284_3840"
     CDS             complement(955..2523)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:TIGR00711.1"
                     /locus_tag="EV284_RS19155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_3840"
                     /product="MFS transporter"
                     /protein_id="WP_207229073.1"
                     /transl_table=11
                     /translation="MMEKKWWTLLGVCGGTFMLLLDTTIVYVVMPDVQRDLNASFADLQ
                     WVIDGYALALASFLLTSGTLADRFGRKRLYAIGVALFTVASLLCGVAQSPLMLIMSRVL
                     QGVGGSVMFATGLALLAGSFQGKERGMAFGVWGMVTGLASAIGPVAGGLISSGISWRGI
                     FLVNVPIGVIVALIIALRVDESKSPFARKLDWPGFVLLTGGLATLVYGLIRAGETEWSD
                     GRAVTGLVAGAALLLAFLLVEAKSEQPMFDLRLFRIPTFVGGSIAAFAMNGSLFAMFLF
                     LAIYFQEALGYSSLETGLRLLTASLSMLVASLVAGRLSAKVQPRYMIGVGLLLVGAALL
                     LMSGITASSGWEHFIPGLVLGGVGAGLVNPPLASTAVGVVDFSRSGMASGVNGTFRQLG
                     VSAGVAVLGSTFAGVISDRFRDGLRGVPELAGRSDQLAALTRGGETGEAVRLVPEQYGE
                     KVQQIATTGFVDGLNTLLAVSAGLALLGGVLALVLIRPADFQAAQQPKPATNDAPGQSP
                     VAAES"
     gene            complement(2567..3985)
                     /locus_tag="EV284_RS19160"
                     /old_locus_tag="EV284_3841"
     CDS             complement(2567..3985)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1138: FAD linked oxidase domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089659.1"
                     /locus_tag="EV284_RS19160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_3841"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_130335730.1"
                     /transl_table=11
                     /translation="MPARPEPLTAREDLSAAARRLAEHVAGPLFAEGQDGYDEERARYQ
                     THRPHRPALVVGATEPKDVQLAVEFAAARDLPVGVQATGHAPALPARTGVLVSTRRMTE
                     VRIDPAARTAFVGAGARWKQVVEAAAPHGLAPLSGSAPDVGVVGYTLGGGIGLLARRFG
                     YAADHVRRVECVTADGRPREVTADSDPDLFWALRGGRDNFGLVTGLEVDLMPVAGLYGG
                     GLYFDGASAERVLNAYLRWTETVPEEMTSSLALVPLPDAPTLPPPLRGRYVVHVRIAYL
                     GDAADGERLVAPLRALGPRLADAVRELPYTESGSIHNDPVAPAAYVGTNAMLSGLDAGA
                     VRTVLELSGPDAPITSIVEVRHLGGALARPPRVPNCVGHRSAGYLLAVLDRVTDDTADT
                     VRAAHTRLTDALSPRTTGRNLNFLYGAAATPDQVRRAYEPGDYARLVRIKAAHDPGNLF
                     RLNHNIPPNPSPGP"
     gene            complement(4117..4716)
                     /locus_tag="EV284_RS19165"
                     /old_locus_tag="EV284_3842"
     CDS             complement(4117..4716)
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1060: 4'-phosphopantetheinyl transferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013786.4"
                     /locus_tag="EV284_RS19165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_3842"
                     /product="4'-phosphopantetheinyl transferase superfamily
                     protein"
                     /protein_id="WP_165425579.1"
                     /transl_table=11
                     /translation="MTETPLPGLPSAWLLGSPGRVRRVVLASAAVAPPGTGAAQHRAGR
                     HAVGAALRRAGSPVTSVGRAYSGAPMSPAGFPASVTHSTALAVAAVAPGARGVGVDLEP
                     RCPDLRLHRFLLDERERAELWPGADPPGLRRLFAAKEAAFKALSECVDAHGGLFWRVRL
                     GLRDGRLWARAGDRYALVGELSAPAFALAVAVTADP"
     gene            complement(4709..5560)
                     /locus_tag="EV284_RS19170"
                     /old_locus_tag="EV284_3843"
     CDS             complement(4709..5560)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (33-141). E-value:
                     1.2e-15. Score: 49.7. Matches aSDomain:
                     nrpspksdomains_EV284_RS19170_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024109.4"
                     /locus_tag="EV284_RS19170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_3843"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_130335734.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 5.2e-15, bitscore:
                     52.5, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 1.1e-11, bitscore: 40.7,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDTTVDDALETGEIQVSDDIRIAYERRGSGPDIVLVNNFFMDRK
                     SWRSYTAKLATTARLTSYDLRGQGDSSRHAGEPVWEDHISDLSALFDGLGLEKAILVGT
                     SFSTLICRDFAVAHPDRVQGLILAGPAMSPHGPQRLRRITKSWLKTLETSGLGVLYEQL
                     YPLVSGDRAVEEAGPIGFMGRKQNFLGIHTVESLRAGLAVSVKAPLDPQIMTKVAAPTL
                     LFVGGDDFSLSTDAVREMVGLFPDAVTVTVPDGGHLAFLEEPEWFQREVESFVERVAGT
                     GD"
     aSDomain        complement(5138..5461)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EV284_RS19170_Abhydrolase_1.1"
                     /evalue="1.20E-15"
                     /label="EV284_RS19170_Abhydrolase_1.1"
                     /locus_tag="EV284_RS19170"
                     /protein_end="141"
                     /protein_start="33"
                     /score="49.7"
                     /tool="antismash"
                     /translation="IVLVNNFFMDRKSWRSYTAKLATTARLTSYDLRGQGDSSRHAGEP
                     VWEDHISDLSALFDGLGLEKAILVGTSFSTLICRDFAVAHPDRVQGLILAGPAMSPHGP
                     QRLR"
     gene            complement(5592..6431)
                     /locus_tag="EV284_RS19175"
                     /old_locus_tag="EV284_3844"
     CDS             complement(5592..6431)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007267316.1"
                     /locus_tag="EV284_RS19175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_3844"
                     /product="hypothetical protein"
                     /protein_id="WP_130335736.1"
                     /transl_table=11
                     /translation="MGTATGTTDNGLGVLGPDELRLLRAFDSLVLSWAHEWEAAERRYP
                     FLLRPVDLESIDYYENFPHLGLAAVAADPARLGELRAGAASPLAELPASVLNDAALALP
                     SAACYSVYFDLKDQALPATENRFTTVATCFRNETRYEGLRRLLGFSMREIVFVGSPEGA
                     TEHLKRAKEQVLGLADRLGLKMSTEVATDPFFDRTGSRATMQRLFPVKEEFVVDGLAIG
                     SVNYHRNFFGERCAISLPDGAPASTSCLAFGLERWVHALTTRFGDARSAAEAVLEAV"
     gene            complement(6431..6679)
                     /locus_tag="EV284_RS19180"
                     /old_locus_tag="EV284_3845"
     CDS             complement(6431..6679)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1147: putative acyl carrier protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012998125.1"
                     /locus_tag="EV284_RS19180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_3845"
                     /product="hypothetical protein"
                     /protein_id="WP_051720141.1"
                     /sec_met_domain="PP-binding (E-value: 2.3e-06, bitscore:
                     23.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDDKLTKILTFIHQRNPEVGELNLDDDLIDRRAVDSLAFVEFLY
                     LLEELSGETIDPEEIDVEDFRTLRAIDKRFLHGAAAR"
     gene            complement(6676..7554)
                     /locus_tag="EV284_RS19185"
                     /old_locus_tag="EV284_3846"
     CDS             complement(6676..7554)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AurF"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012998126.1"
                     /locus_tag="EV284_RS19185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_3846"
                     /product="diiron oxygenase"
                     /protein_id="WP_130335738.1"
                     /sec_met_domain="AurF (E-value: 6.3e-35, bitscore: 116.6,
                     seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTTVKPVKLDLARLEAMAESDYYNPYTIFDWPESLGTDRPWMSE
                     DLVTLAGTEEWGKLTREQQLALTRFEAVNFFSLNVHGIRELLSEVVLRIHTKTYADASE
                     FLHHFIGEENEHMWFFGTFCLKYGGKVYPAVPQVGPGRIEGVGDAATELVIFARILIFE
                     ELVDYFNARMATDDALPPIAQEINRVHHQDESRHVAFGRHLFTQLLDQVKESRPEDIPV
                     LANYLETYLEYSVRSLYNPAVYRDAGLDQPLELRRRLLEHPARHAAHDAILNRTRKFLA
                     RNGLQVQGASA"
     gene            complement(7601..8311)
                     /locus_tag="EV284_RS19190"
                     /old_locus_tag="EV284_3847"
     CDS             complement(7601..8311)
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009075331.1"
                     /locus_tag="EV284_RS19190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_3847"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_130335740.1"
                     /transl_table=11
                     /translation="MSNSAQKSYDYATADFNAVYRGGELLGDAGITRVPWDIGEPQPGV
                     LEFERRGRIRGEVLDAGCGLGDNAVFLAARGYRVTAVDAASTAIERARERAAKQEGATE
                     IEFAVADATSLAGYEGRFDTVLDSALFHTLDADGRRRYAAALGRAARPGAWLDMLCFAA
                     VPGGMPEPLSVSEETVREVLTGAGWTVTELTRTVYWGVAEATRTFLEKTGVQVEIDEAG
                     RTQLPVWSVLAERA"
     gene            8693..9889
                     /locus_tag="EV284_RS19195"
                     /old_locus_tag="EV284_3848"
     CDS             8693..9889
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1191: acyl-CoA dehydrogenase type 2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019640.4"
                     /locus_tag="EV284_RS19195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_3848"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_207229074.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.1e-07, bitscore:
                     28.4, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 8.4e-11, bitscore:
                     38.1, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRGSGNNLDARAAELVNQAAGLREELWKRAADSDRDRRLPDEVMA
                     RVTGAGLTRLLVPESNGGHETSVRTLLEVCTELGRGCVSAAWVAGVLNVGNFVVSLFPE
                     RTRAEVWDDDPDARTALILGAPVRTVEPVDGGVRVSGEWPYASGSLHAEWIGGLLLADT
                     GTGLQPHFALMPAADITVRDTWHFVGMRGTGSNTVVAEKVFVPAHRLLPYKPLIDGESD
                     GLVPADRRYRNSLTGVFMVGLIGSLLGGADTALRHALDHAGTRRVAGTTFASQAESPTA
                     RLALAAAATRLDTARLHARRLADNVDAHARAGENPDLLTRARARMDATHVVQQCRQAVD
                     DIVTLYGSSALDESNPLQRLWRDIHTGSRHAGFGMGVPEQVYGSALVGQDPRAISMLV"
     gene            10001..10462
                     /locus_tag="EV284_RS19200"
                     /old_locus_tag="EV284_3849"
     CDS             10001..10462
                     /GO_process="GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phenazine: phzB"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018960032.1"
                     /locus_tag="EV284_RS19200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_3849"
                     /product="PhzA/PhzB family protein"
                     /protein_id="WP_207229075.1"
                     /sec_met_domain="phzB (E-value: 9.5e-69, bitscore: 227.7,
                     seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDEYEIREQNRAVVAQYMNTRGQDRLKRHLLFTEDGTGGLWTTE
                     TGEPIVISGRDRLGEHAVWSLKCFPDWAWINVEIFDTQDPDRFWVECDGEGQILFPGYE
                     PGLYRNHFLHSFTFENGKIKQQREFMNPCQQFRALGIDVPAVRRDGIPT"
     gene            10513..11685
                     /locus_tag="EV284_RS19205"
                     /old_locus_tag="EV284_3850"
     CDS             10513..11685
                     /EC_number="2.5.1.54"
                     /GO_function="GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018960031.1"
                     /locus_tag="EV284_RS19205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_3850"
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="WP_130335744.1"
                     /transl_table=11
                     /translation="MRPSLQDIHASLALQQPQWDDARPVERVRATLRTCPPLVTADAAE
                     GLRHLLADVAAGRALLLQAGDCAEDPAESSTRHVRRKTDLLDHLAEAAGAVTGKPVLRV
                     GRIAGQFAKPRSKPVEQVGGITLPVFRGHMVNAPEADPVSRRADPERILTCHQAAREIV
                     RELADVNAGRPPAEQVWTSHEALLLDYELPMLRQDGTRTYLGSTHLPWIGERTRRPDGA
                     HVRLLAEVSNPVACKIGSGTTTEDVTALAHRLDPHREAGRLVLVARMGTDFVASRLPPL
                     VEAVRAAGHPAIWLCDPMHGNTITSPAGHKTRLVDAMLAEIEGFGTALAESGGVNGGLH
                     LETTPDDVTECAADVSQLGSVGDRHTTFCDPRLNPGQALRMVTGWAHTLR"
     gene            11804..12427
                     /locus_tag="EV284_RS19210"
                     /old_locus_tag="EV284_3851"
     CDS             11804..12427
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027: isochorismatase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019547161.1"
                     /locus_tag="EV284_RS19210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_3851"
                     /product="isochorismatase family protein"
                     /protein_id="WP_130335746.1"
                     /transl_table=11
                     /translation="MVGIPRIAPYALPAADSLPANTAHWTPDPQRATLLIHDMQHFFLR
                     SVPDPLRSELVDNAARLRKRAASLAVPVAYTAQPGGMSDEDRGLLKDFWGPGMRTAPED
                     REVVPELAPEPGDWVLTKYRYSAFHRSGLLRRLRAAGRDQLVLCGVYAHIGVLATAVEA
                     FTNDIQVFLAADAVADFSAERHRLALEYVAERCGVVLPSAEVFR"
     gene            12424..14325
                     /locus_tag="EV284_RS19215"
                     /old_locus_tag="EV284_3852"
     CDS             12424..14325
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1018: isochorismate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020132915.1"
                     /locus_tag="EV284_RS19215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_3852"
                     /product="anthranilate synthase family protein"
                     /protein_id="WP_207229076.1"
                     /transl_table=11
                     /translation="MSPPSDLLGRLLAAPGDQDFALLHRPESGTPGMVDVLLGEVSHPA
                     TLAGLPLPEGRDTPGHETLVLVPYRQLAERDFAAPDDGSPLVALTVTEQAELPLADVLE
                     RLPDTPVGMSGHRFDLSDDEYAEKVRRVVADEIGTGEGANFVLRRTLLADLDGYTPHTA
                     LAVFRRLTAVEHSAYWTFVIHVGGRSFVGATPERHISVRRGHAVMNPISGTYRYPPGGA
                     DLAGLTAFLQDRKETDELYMVLDEELKMMSRICEPGVRVTGPRLKEMARLAHTEYFIEG
                     RTRRDLRDILRETLFAPTVTGSPVESAARVIQRHEPQGRGYYSGLAALISREPGGGRSL
                     DSAILIRTADIAADGRLRLAVGATLVRHSSPRAEAAETRAKAAGLLHALGGAAGPDVPP
                     LPAARFGDRPEVREALRGRNADIADFWLGTTPPGALRVPELKGRKILVVDAEDAFTAMI
                     VQQLEALGPTAEVLRYDRLHGRLDGFDAVVMGPGPGDPQDTADPKIAALDAAVAQLLGD
                     RLPFLAVCLSHQVLSRRLGLPLIRRAEPNQGLQRAIDLFGRPERVGYYNTFAAVSPADR
                     HHVPGTGEVAVSRDPETGEVDALRGPHFASFQFHAESVLTVDGPRLLGDALRGVLAR"
     gene            14322..14648
                     /locus_tag="EV284_RS19220"
                     /old_locus_tag="EV284_3853"
     CDS             14322..14648
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) thio_amide"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EV284_RS19220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EV284_3853"
                     /product="hypothetical protein"
                     /protein_id="WP_130335748.1"
                     /sec_met_domain="thio_amide (E-value: 1.6e-12, bitscore:
                     43.2, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLEIAWWDLDDSPQSIRTLNAHLSEGVTGDWAGVPGLKVKYWVA
                     DQAHNRWGAVMVWETDRPAGQPLPPNRAADLIGRPPDHRMGFAVEALADPTALPIPQVT
                     QEPR"
     gene            14648..15481
                     /locus_tag="EV284_RS19225"
                     /old_locus_tag="EV284_3854"
     CDS             14648..15481
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019358208.1"
                     /locus_tag="EV284_RS19225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_3854"
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="WP_130335750.1"
                     /transl_table=11
                     /translation="MHEYLVVDAFSRKPLYGNPVAVFLDAGDLSAETMQRIAREMNLSE
                     TTFVHPARDGGDARIRIFTPVNELPFAGHPLLGTAVALGEVRGRDRLRLETAMGTIPVE
                     LGDDDGAVTVRMRQPHPVWEPYEHAGELLDALGVTQTVAPVEIYRNGPRHVFVGLESVA
                     ALSALTPDHRALARFPDMAANCFAGEGSHWRTRMFSPAYGVVEDAATGSAAGPLAIHLA
                     RHGLAAYGQPLEILQGVEMGRPSLMLATAEGTGEHITSVQVGGHGVTVGRGNLYV"
     gene            15509..16147
                     /gene="phzG"
                     /locus_tag="EV284_RS19230"
                     /old_locus_tag="EV284_3855"
     CDS             15509..16147
                     /EC_number="1.10.3.16"
                     /GO_function="GO:0016682 - oxidoreductase activity, acting
                     on diphenols and related substances as donors, oxygen as
                     acceptor [Evidence IEA]"
                     /codon_start=1
                     /gene="phzG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018837181.1"
                     /locus_tag="EV284_RS19230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_3855"
                     /product="phenazine biosynthesis FMN-dependent oxidase
                     PhzG"
                     /protein_id="WP_130335752.1"
                     /transl_table=11
                     /translation="MNSSKFESLTGRTDRGFPEYDDPPAEPLGLVRAWLAQAVEQGVRE
                     PRALALATADKRGRASTRVVVFGGIDDRGLLFTTHSTSRKSRDIEETGWASGLLYWRET
                     AQQISIGGPAVPIGEAEADALWHARPVPLHAMSAASQQSEPLTDPDALRAAAESLAATG
                     AALARPARFTGYRLVPHEVEFWSARSDRMHHRLRYERDGADWHVTRLQP"
     gene            16177..16560
                     /locus_tag="EV284_RS19235"
                     /old_locus_tag="EV284_3856"
     CDS             16177..16560
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013098.4"
                     /locus_tag="EV284_RS19235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_3856"
                     /product="VOC family protein"
                     /protein_id="WP_130335754.1"
                     /transl_table=11
                     /translation="MQERAFPLVFAEHVPATAAFYERLGFTRLRQNPPEGEPTYIALAR
                     GTAELAVVSTDWPATRYDRPPGTGVRFEMFVLVEDLDTLLKELAGAGVPLLRDPVEMPW
                     GERIAYVTDPDGNPVALAAGPHS"
     gene            16582..17691
                     /locus_tag="EV284_RS19240"
                     /old_locus_tag="EV284_3857"
     CDS             16582..17691
                     /NRPS_PKS="Domain: AMP-binding (89-319). E-value: 8.1e-11.
                     Score: 33.0. Matches aSDomain:
                     nrpspksdomains_EV284_RS19240_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018960023.1"
                     /locus_tag="EV284_RS19240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_3857"
                     /product="phenazine antibiotic biosynthesis protein"
                     /protein_id="WP_130335756.1"
                     /sec_met_domain="AMP-binding (E-value: 3.4e-08, bitscore:
                     28.3, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLDIAETDRILEPPHGTRPDPDAFVQAAMAWHFDPDTGSPFWLK
                     RATAFDFDPRRDIRTHADLARFPNVAAELRHVPAADLVPRGYGDRPDVIGVYESGGTTG
                     APKRVVLLRDWLERTLHWSNEALDAHGFPRGADWLGLVPGGPHIVGEYFQRSAATHGRY
                     GFRVDLDPRWVKRTIAEGRGPEAGAYAEHVIDQAAEVLRTQDIGVMTITPPLLERLARR
                     DDLVDLVNDKVRAIRWGGTQMDADSRHLYRTEVFPDTVLSGNYGSTMILGFAGERPGLP
                     DDAPCVFDTLDPWVTFGVVDPETGRPVPYGERGRVVAHHVSKSFLLPNNLERDLATRVR
                     PPEGGSGDSVADIAPVGVFENETVIEGVY"
     aSDomain        16849..17538
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EV284_RS19240_AMP-binding.1"
                     /evalue="8.10E-11"
                     /label="EV284_RS19240_AMP-binding.1"
                     /locus_tag="EV284_RS19240"
                     /protein_end="319"
                     /protein_start="89"
                     /score="33.0"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="RPDVIGVYESGGTTGAPKRVVLLRDWLERTLHWSNEALDAHGFPR
                     GADWLGLVPGGPHIVGEYFQRSAATHGRYGFRVDLDPRWVKRTIAEGRGPEAGAYAEHV
                     IDQAAEVLRTQDIGVMTITPPLLERLARRDDLVDLVNDKVRAIRWGGTQMDADSRHLYR
                     TEVFPDTVLSGNYGSTMILGFAGERPGLPDDAPCVFDTLDPWVTFGVVDPETGRPVPYG
                     ERGRVVAH"
     gene            17691..19082
                     /locus_tag="EV284_RS19245"
                     /old_locus_tag="EV284_3858"
     CDS             17691..19082
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006131886.1"
                     /locus_tag="EV284_RS19245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_3858"
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="WP_130335758.1"
                     /sec_met_domain="Aldedh (E-value: 3.4e-12, bitscore: 41.4,
                     seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPPALEEEELPQLDALGPRGPYRARNRLTVTDVSGAPVAQLSLVP
                     GVFLHRALTALRRAEPATPDRRAAVLARAAELFTTGRVGGLTVTEHEHLVSRVGGVPLG
                     VVRTATRAIGERLAAAYDSARRARPVDARDDWRDPLTRAGRAVWTRRGEVFAVNAAGNH
                     PGTHSLWPEALALGFRVAVRPSRREPFTPYRLITALREAGLGPDQVAFLPTGHELADEL
                     LRGADLGMVYGGDDAVRRHRTDPAVLTQGPGRSKILVTADVDWREHLDTIVDSVSHHGG
                     TGCVNATAVLVEGDPAPLCAALAERLGALPALAPEDDKAVLPVQPLATAQAFGAHLANR
                     AAGTRPWLGAEGVVAELGDGSAALRPAVHQVDRPDAAQLGVELPFPCVWVAPWTPDAGT
                     AVLRDSLVVTALTTREELIDRLLDEPTIGNVYVGDTPTYRIAPGLPHDGFLGDFLMRTK
                     AVIRT"
     gene            19139..19963
                     /locus_tag="EV284_RS19250"
                     /old_locus_tag="EV284_3859"
     CDS             19139..19963
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015609404.1"
                     /locus_tag="EV284_RS19250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_3859"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_130335760.1"
                     /transl_table=11
                     /translation="MHAVSYTAQWMAAARALESEREDALYVDPLARDLAEPKGFELIDR
                     YVGGGLLPFISIRTRFLDDAIRDLLADGSIGQVVLIAAGMDTRAFRLDWPDDVDVYEVD
                     HGPLITEKRRRLDALGAKPSVKRHEVSADLTKEWLPDLEAAGFDRTRPTLWVAEALTFF
                     LTEEQAAGLLRLLASASAPGSHLAFDILGRTLLRSPFSKPFLDRLAEDGTPWIFGTDEP
                     EPFLEAGGWEVESLKEPGQPGAGEGRWPYEVQPRGRRFANRLWLIRARLAAR"
     misc_feature    20442..20460
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 20.0"
                     /tool="antismash"
ORIGIN
        1 ggtacttcat cgccgtggca caggaagcca atttcaccag ggccgcggag ctggtgcata
       61 tcagccagcc tgggatcagc gcccagatcc gccagctgga gaacgacctg ggggccaccc
      121 tgatcgaccg ctccggccgc agtgtgcagc tcacggcggt cggcgaggtg gtgctggcgc
      181 acgccaagtc cgtgctgtcc tcgatggact cgctgcggca ggccgtggac gagatgaacg
      241 gcctggtccg gggcaagctg gtcgtcggca tggtcaccgc ctgcaccgtc cagccgctgt
      301 tcgacgcgct gtccggcttc catctggccc accccggcgt cgagatcagc ctgctcgagg
      361 acgattcggc caagctggtc gagtacgtcc gggagggcac cgtcgacctg gcgctgatcg
      421 gcgccgccca tcgcgcgccg gacgacctgg acggctggca ggtgatcagc gagccgatcg
      481 tcgccgccgt gccgcacgag cacccgctgg ccgaaaagga cggggtcacc ctcgccgaac
      541 tgagcgcctt cccgctcgtc tgcctgcccg aggggaccgg aatccgggcg acgctggacc
      601 aggcttccgc cgcgctgggc ctcaccccga ccatcgcgct gcaggcgagc gcgcccggcg
      661 cggtgatgca gctggccgag cggggcctcg gggtcgcggt gctctccgag tcgatgaccg
      721 gccatcagaa ggggctcaag accgtcgcca tcaccgacgc cgacgtcccc gcggtactcg
      781 ccctgatctc cgcgcccacc aagagccccg cgctgcgcga actgctgctg cactgccggc
      841 agtccttcgg cgagccggct gcgacgcagg tcgcctcgat gagcggcgcg tgacccgaca
      901 gcacgaagag cgggcccgtc ggcgaccgac gggcccgctt tccgttgacc ggactcagct
      961 ctccgccgcc accggggact gaccgggagc gtcgttcgtc gcgggcttcg gctgctgggc
     1021 cgcctggaag tcggcgggcc ggatcagcac cagggccagc acaccaccga gcagggccag
     1081 gccggccgac acggcgagca gggtgttgag gccgtccacg aacccggtcg tggcgatctg
     1141 ctgcaccttc tccccgtact gctccggcac cagccgcacc gcctcaccgg tctcgccgcc
     1201 ccgcgtcagc gcggccagct ggtcgctgcg gcccgccagt tcgggcaccc cacgcagtcc
     1261 gtcgcggaag cggtcgctga tgacaccggc gaaggtcgag ccgagcaccg cgacacccgc
     1321 gctcacaccg agctgacgga aggtgccgtt cacacccgac gccatgccgg accgggagaa
     1381 gtccacgacg cccacggccg tggaggccag cggcgggttc accagaccgg cgccgacacc
     1441 gcccagcacc agaccgggga tgaagtgctc ccagccgctg gacgcggtga tcccgctcat
     1501 cagcagcagg gcggcaccga ccagcagcag cccgacgccg atcatgtagc ggggctgcac
     1561 cttggcgctg agccgcccgg cgaccaggga ggcgaccagc atcgacagcg aggcggtgag
     1621 caggcgcagg cccgtctcca gcgaggagta gcccagcgcc tcctggaagt agatcgccag
     1681 gaacaggaac atcgcgaaca gcgagccgtt catggcgaac gcggcgatgg agccgccgac
     1741 gaaggtgggg atgcggaaca gcctcaggtc gaacatcggc tgctcggact tcgcctccac
     1801 cagcaggaag gcgagcagca gcgccgcgcc cgccaccaga ccggtcaccg cccggccgtc
     1861 gctccactcg gtctcgccgg cgcggatcag accgtagacc agggtggcga ggccgccggt
     1921 gagcaggacg aagccgggcc agtccagctt gcgggcgaac ggcgacttcg actcgtccac
     1981 gcgcagcgcg atgatcagcg ccacgatcac accgatcggc acgttgacca ggaagatgcc
     2041 ccgccagctg atgccgctgg agatcaggcc gccggccacc gggccgatgg cggaggcgag
     2101 gccggtgacc atgccccaca cgccgaacgc catgccgcgt tccttgccct ggaagctgcc
     2161 cgcgagcagc gccagaccgg tggcgaacat gaccgagccg cccacgccct ggagcacccg
     2221 ggacatgatc agcatcagcg gcgactgggc cacaccgcac agcagcgagg cgaccgtgaa
     2281 cagggccacg ccgatcgcgt agaggcgctt gcggccgaac cggtcggcca gcgtgccgct
     2341 ggtcagcagg aaggaggcca gcgccagcgc gtagccgtcg atcacccact ggaggtcggc
     2401 gaagctggcg ttcaggtcac gctgcacatc gggcatgacg acgtacacga tggtggtgtc
     2461 cagcaggagc atgaacgtcc cgccgcacac ccccaacagg gtccaccatt tcttttccat
     2521 catcgttcct tctgctgtcc tgagcggtcg gcccgcggcc cgtcagctac gggccggggg
     2581 aggggttcgg cgggatgttg tggttcagcc ggaagaggtt cccggggtcg tgggcggcct
     2641 tgatccggac caggcgcgcg tagtcgccgg gttcgtacgc ccggcgcacc tggtcggggg
     2701 tggcggcggc gccgtagagg aagttcaggt tgcggcccgt ggtgcgcggg gacagggcgt
     2761 cggtgagccg ggtgtgcgcg gcgcggacgg tgtcggcggt gtcgtcggtg acccggtcga
     2821 gcaccgcgag cagatagccg gccgagcggt ggccgacgca gttcggcacc cgcggcggcc
     2881 gggccagcgc gccgcccaga tggcgcacct cgacgatgct ggtgatcggc gcgtccgggc
     2941 cggacagctc cagtacggtc cgcaccgcgc ccgcgtccag ccccgagagc atcgcgttgg
     3001 tccccacgta cgcggccggc gccaccgggt cgttgtggat ggaacccgac tcggtgtacg
     3061 gcagctcgcg caccgcgtcc gccagccggg gacccagcgc ccgcagcggg gcgaccagcc
     3121 gctccccgtc ggccgcgtcg ccgaggtagg cgatccggac gtgcaccacg taccgcccgc
     3181 gcagcggcgg gggcagcgtc ggcgcgtcgg gcagcgggac cagggccagg gaggaggtca
     3241 tctcctcggg gaccgtctcc gtccagcgca ggtaggcgtt gagcacgcgc tcggccgagg
     3301 cgccgtcgaa gtacaggccc ccgccgtaga gcccggccac cggcatcagg tccacctcga
     3361 ggccggtgac cagtccgaag ttgtcccggc cgccgcgcag cgcccagaac aggtccgggt
     3421 cgctgtcggc ggtgacctcg cggggccggc cgtcggcggt gacgcactcc acgcgccgga
     3481 cgtggtcggc ggcgtacccg aacctgcggg ccagcaggcc gattccgccg cccagggtgt
     3541 agccgacgac gcccacgtcc ggggcgctgc cgctgagcgg ggccagaccg tgcggcgcgg
     3601 ccgcctcgac gacctgcttc caccgcgcgc ccgcgcccac gaaggcggtc cgggcggccg
     3661 ggtcgatgcg tacctcggtc atccggcggg tgctgacgag gaccccggtg cgggcgggca
     3721 gcgcgggggc gtgcccggtg gcctgcacgc ccaccggaag gtcgcgcgcg gcggcgaact
     3781 ccaccgcgag ctggacgtcc ttgggctcgg tcgcgccgac gacgagcgcc gggcggtgcg
     3841 gccggtgggt ctggtagcgg gcgcgttcct cgtcgtagcc gtcctggccc tcggcgaaca
     3901 gcgggccggc gacgtgctcg gccagtcgcc gggcggccgc actcaggtcc tcgcgcgcgg
     3961 tgagcggttc ggggcgagcg ggcacggtcc gttcctttcg tcgagggacg acagtgccgc
     4021 tgacgggggt cgctgcggca ctgccgtccc agtcatggtc ccgacgatgc gatcagaagt
     4081 ccaagaccta gtttttctgg gataccgaac ttttggttat ggatcagcgg tgaccgccac
     4141 ggccagcgcg aacgccggtg ccgacagctc cccgaccagc gcgtaccggt ccccggcccg
     4201 cgcccacagg cgcccgtcgc ggaggccgag ccgcacccgc cagaacagcc cgccatgggc
     4261 gtccacgcac tccgagagcg ccttgaaggc ggcctccttc gcggcgaaca gccgccgcag
     4321 gcccggggga tcggcgccgg gccacagctc ggcccgctcc cgctcgtcca gcaggaaccg
     4381 gtgcagccgg aggtccgggc agcgcggctc caggtccacg cccaccccgc gcgcgccggg
     4441 cgcgacggcg gccaccgcca gcgcggtgct gtgggtcacc gaggccggga accccgccgg
     4501 gctcatcggc gccccgctgt aggcgcggcc caccgacgtg accgggctgc ccgcgcgccg
     4561 cagcgccgcg cccaccgcgt gccggccggc ccggtgctgg gccgcgccgg tacccggcgg
     4621 ggcgaccgcg gcgctcgcca gcaccacccg ccggacacga ccggggctcc cgagcagcca
     4681 tgcgctcggg agccccggaa gcggtgtctc agtcacccgt cccggcgacc cgctcgacga
     4741 acgactccac ctcccgctgg aaccactcgg gctcctccag gaaggccaga tgcccgccgt
     4801 ccggcacggt gacggtgacg gcgtccggga acagccccac catctcccgt accgcgtccg
     4861 tgctcagcga gaagtcgtcc ccgccgacga acagcagggt cggggccgcc accttggtca
     4921 tgatctgcgg gtccagcggt gccttcaccg acaccgcgag cccggcgcgc agggactcca
     4981 cggtgtggat gccgaggaag ttctgcttgc ggcccatgaa cccgatgggc cccgcctcct
     5041 ccaccgcccg gtcaccggag acgagcgggt acaactgctc gtacagcacg cccagtccgg
     5101 acgtctccag cgtcttcagc caggacttgg tgatccggcg cagccgctgc gggccgtgcg
     5161 ggctcatcgc cggccccgcc aggatcaggc cctgcacccg gtccgggtgg gccacggcga
     5221 agtcccggca gatcagcgtc gagaacgacg tgcccaccag gatcgccttc tccaggccca
     5281 gcccgtcgaa cagggccgac aggtcgctga tgtggtcctc ccacaccggc tccccggcgt
     5341 gccggctgga gtcgccctgg ccgcgcaggt cgtatgaggt gagccgggcc gtggtggcca
     5401 gcttcgcggt gtaggaccgc caggacttgc ggtccatgaa gaagttgttg acgaggacga
     5461 tgtcggggcc ggacccgcgt cgctcgtacg ctatccggat gtcgtcgctc acctggatct
     5521 cgccggtctc cagggcgtcg tcgacggtcg tgtcggtcat cggctcactt tcggcggagg
     5581 gcgggcgggg ctcagacggc ttcgaggacc gcctcggcgg cggaccgggc gtcaccgaac
     5641 cgggtggtca gcgcgtgcac ccaccgctcc aggccgaagg ccaggcagct ggtggaggcg
     5701 ggcgcgccgt cgggcaggga gatcgcgcag cgctccccga agaagttgcg gtggtagttc
     5761 accgacccga tggccaggcc gtccaccacg aactcctcct tcaccgggaa gagccgctgc
     5821 atcgtggccc gtgacccggt gcggtcgaag aacgggtcgg tggcgacctc ggtgctcatc
     5881 ttcaggccca gccggtcggc gagccccagc acctgctcct tggcccgctt caggtgctcg
     5941 gtggcgccct cgggggagcc gacgaacacg atctcgcgca tgctgaagcc cagcagcctg
     6001 cgcaggccct cgtagcgcgt ctcgttgcgg aaacaggtgg cgaccgtggt gaagcggttc
     6061 tccgtcgccg gaagggcctg gtccttcaga tcgaagtaga ccgagtagca ggcggccgaa
     6121 ggcagcgcca gcgcagcgtc gttgagaacg gaggccggca gctccgccag cgggctcgcg
     6181 gcaccggcgc gcagctcccc gagccgggcc ggatcggccg cgacggccgc cagacccagg
     6241 tgcgggaagt tctcgtagta gtcgatggac tccaggtcaa ccggccgcag caggaacggg
     6301 tagcgccgct ccgccgcctc ccactcgtgc gcccaggaca gcaccagcga gtcgaacgcg
     6361 cgcagcagcc gcagctcgtc cgggccgagg acgccgaggc cgttgtccgt cgtccccgtc
     6421 gcggtgccca tcagcgcgcc gccgcgccgt gcaggaaacg cttgtcgatg gcgcgcaggg
     6481 tgcggaagtc ctcgacgtcg atctcctcgg ggtcgatggt ctccccgctc agctcctcca
     6541 gcaggtagag gaactcgacg aacgccagcg agtccaccgc gcggcggtcg atcaggtcgt
     6601 cgtccaggtt cagctcgccc acctcggggt tgcgctggtg gatgaaggtg aggatcttgg
     6661 tcagcttgtc gtcgctcatg ccgatgctcc ttggacctga aggccgttgc gggcgaggaa
     6721 cttgcgggtg cggttgagga tcgcgtcgtg cgcggcgtgc cgggccgggt gttccagcag
     6781 gcggcggcgc agttcgaggg gctggtcgag cccggcgtcg cggtacacgg ccgggttgta
     6841 caggctgcgg acgctgtact ccaggtacgt ctccaggtag ttggccagca ccgggatgtc
     6901 ctccgggcgg ctctccttga cctggtccag cagctgggtg aacaggtgcc gcccgaaggc
     6961 gacatggcgg ctctcgtcct ggtggtggac gcggttgatc tcctgcgcga tgggcggcag
     7021 cgcatcgtcc gtcgccatcc gggcgttgaa gtagtcgacc agctcctcga agatcaggat
     7081 gcgggcgaag atgaccagtt cggtcgccgc gtcgcccacc ccctcgatcc ggcccggacc
     7141 gacctgcggc accgccgggt acaccttccc gccgtacttc aggcagaagg tcccgaagaa
     7201 ccacatgtgc tcgttctcct caccgatgaa gtggtggagg aactccgagg cgtcggcgta
     7261 ggtcttggtg tggatgcgga gcacgacctc gctgagcagc tcgcggatgc cgtgcacgtt
     7321 gaggctgaag aagttcaccg cctcgaaccg ggtcagggcg agctgctgct cccgcgtcag
     7381 cttcccccac tcctcggtgc cggcgagcgt gaccaggtcc tcgctcatcc acggccggtc
     7441 ggtgccgagg gactcgggcc agtcgaagat cgtgtacggg ttgtagtagt cggactccgc
     7501 catcgcttcc agccgggcca ggtccagctt cacgggtttg acggtcgtcg gcatcggcag
     7561 accttctttc ggggaacgtt gcggtacggc ggcgcgcggg tcaggcgcgc tcggccagga
     7621 cggaccagac cggcagctgg gtgcgtcccg cctcgtcgat ctccacctgg acgccggtct
     7681 tctccaggaa ggtgcgggtg gcctcggcca cgccccagta gacggtccgg gtcagctccg
     7741 tcaccgtcca gccggccccg gtcagcacct cgcgcaccgt ctcctcggag acggacagcg
     7801 gctcgggcat cccgccgggg accgccgcga agcacagcat gtccagccag gcaccgggcc
     7861 gggcggcccg gccgagcgcg gcggcgtacc ggcggcgccc gtccgcgtcg agcgtgtgga
     7921 acagcgcgct gtccaggacg gtgtcgaagc ggccctcgta tccggccagg ctggtggcat
     7981 cggcgacggc gaactcgatc tccgtggcgc cttcctgctt cgccgcccgc tccctggccc
     8041 gctcgatcgc cgtggaggcg gcgtcgacgg cggtgacccg gtagccgcgg gcggccagga
     8101 acacggcgtt gtcacccaga ccacagcccg cgtccagcac ctcgccgcga attcgtccgc
     8161 ggcgctcgaa ttcaagcaca ccgggctgcg gttcaccgat gtcccagggg acccgggtga
     8221 tcccggcgtc acccagcagt tcacctccgc gatatacggc gttgaagtcg gcggtcgcgt
     8281 aatcgtagga cttctgggcg ctattgctca tgccagtctc ctgaggaata gatccggcgt
     8341 ccggccctgt cgaaccaaag ggattaccac agcctccggc gcccgcgtaa ggcgtgccga
     8401 cgcgctccgg cgcccgttca accgaggaga ttccacggtt gaacgcccgt tccctggtgg
     8461 ccgggtggac ggaaagagcg tattccgctt ttcccggccg cgggcgcccg gcgacggcgg
     8521 tcaagcggaa cgaaaagttt cgtatccggc gcggcgaatt caacgggggt ggctgcgccg
     8581 aacgggccca cgtacgatgc cggggcggcc ggaggaaacg gaccgccaat cgtccggagc
     8641 gccatccgca ccggggctct ctgcgtcccg aaaatccgga aggaaaaaga aattgcgcgg
     8701 ttcaggaaat aacctcgacg cgcgtgccgc ggagctggtg aaccaggccg ccggccttcg
     8761 cgaggaactc tggaaacgcg ccgccgacag cgaccgcgac cggcggctgc ccgacgaggt
     8821 catggcccgc gtcaccggcg ccggactgac ccggctgctg gtgcccgaga gcaacggcgg
     8881 ccacgagacc tcggtacgca ccctgctgga ggtctgtacc gagctgggcc gcggctgcgt
     8941 ctccgcggcc tgggtcgccg gcgtgctcaa cgtcggaaac ttcgtcgtct ccctcttccc
     9001 cgagcgcacc cgcgccgagg tctgggacga cgaccccgac gcccgtaccg cgctcatcct
     9061 cggtgccccc gtgcgcaccg tggaaccggt ggacggcggg gtccgggtca gcggtgaatg
     9121 gccctacgcc tccggctcgc tgcacgccga gtggatcggc ggactgctgc tcgccgacac
     9181 cggcaccgga ctccagccgc acttcgcgct gatgccggcc gccgacatca ccgtccgcga
     9241 cacctggcac ttcgtcggga tgcgcggcac cggcagcaac acggtcgtcg ccgagaaggt
     9301 gttcgtgccc gcgcaccggc tgctgcccta caagcccctg atcgacggcg agagcgacgg
     9361 cctggtgccg gccgaccgcc gttaccggaa cagcctgacc ggcgtcttca tggtcggcct
     9421 gatcggctcg ctgctcggcg gcgccgacac cgccctgcgc cacgccctgg accacgccgg
     9481 gacccggcgc gtggccggca ccaccttcgc cagccaggcc gagtcgccca ccgcccggct
     9541 cgccctcgcg gccgccgcca cccggctgga caccgcccgg ctgcacgccc gccgcctcgc
     9601 cgacaacgtg gacgcgcacg cccgggcggg ggagaacccc gacctgctca cccgggcccg
     9661 cgcccgcatg gacgccaccc atgtcgtcca gcagtgccgc caggccgtcg acgacatcgt
     9721 cacgctctac ggctcctccg ccctggacga gtccaacccc ctccagcggc tctggcgcga
     9781 catccacacc ggcagccggc acgccggctt cggcatgggc gtccccgagc aggtctacgg
     9841 cagcgccctg gtcggccagg acccgcgcgc catcagcatg ctggtctgac acccccgtac
     9901 gaccaccgcg aactcccctt cgttccgatg tgctccaggc ccgtccgccc cggcgcggca
     9961 gcggcccttc gcctcccagt gacggaaagc gagaccagac atgtccgacg agtacgagat
    10021 ccgcgaacag aaccgcgccg tcgtcgccca gtacatgaac acccgcggcc aggaccgcct
    10081 caagcggcac ctgctgttca ccgaggacgg caccggcggc ctgtggacca ccgagaccgg
    10141 cgagcccatc gtcatcagcg gccgggaccg gctcggcgag cacgccgtct ggtcgctcaa
    10201 gtgctttccc gactgggcct ggatcaacgt cgagatcttc gacacccagg accccgaccg
    10261 gttctgggtg gagtgcgacg gcgagggcca gatcctcttc cccggctacg agcccggtct
    10321 gtaccgcaac cacttcctgc actccttcac cttcgagaac gggaagatca agcagcagcg
    10381 cgagttcatg aacccctgcc agcagttccg ggccctcggt atcgacgtcc ccgcggtccg
    10441 ccgcgacgga atcccgacct gacgccggcc ggccggcccc cggtccccgc cccgaccccg
    10501 caagaggaag ccgtgcgccc ctccctccag gacatccacg cctcactcgc cctgcagcag
    10561 ccccagtggg acgacgcccg cccggtcgag cgggtgcgcg ccaccctccg cacctgtcca
    10621 cccctggtca ccgccgacgc cgccgaaggg ctgcgccacc tgctcgccga cgtcgccgcc
    10681 gggcgggccc tgctgctcca ggcgggggac tgcgccgagg accccgccga gtccagcacc
    10741 cggcacgtgc gccgcaagac cgacctcctc gaccacctcg cggaggcggc cggcgcggtc
    10801 accggcaagc ccgtgctgcg cgtcggccgg atcgccggac agttcgccaa accccgctcc
    10861 aagcccgtgg agcaggtcgg cggcatcacc ctgcccgtct tccgcggcca catggtcaac
    10921 gcgcccgagg ccgacccggt cagccgccgc gccgaccccg agcgcatcct cacctgccac
    10981 caggccgccc gggagatcgt ccgggaactg gcggacgtca acgccggccg gccgcccgcc
    11041 gaacaggtgt ggaccagcca cgaggcgctg ctgctcgact acgaactgcc catgctgcgc
    11101 caggacggca cccgcaccta cctgggctcc acgcacctgc cgtggatcgg ggaacgcacc
    11161 cgccggcccg acggcgccca tgtgcggctg ctcgccgagg tgtcgaaccc ggtcgcctgc
    11221 aagatcggct ccggcaccac caccgaggac gtcaccgccc tggcccaccg tctcgacccg
    11281 caccgcgagg ccggccggct cgtgctggtc gcccgcatgg gcaccgactt cgtggccagc
    11341 aggctgcccc cgctggtgga ggccgtacgg gccgccggac acccggcgat ctggctgtgc
    11401 gaccccatgc acggcaacac catcaccagc cccgccggcc acaagacccg cctggtggac
    11461 gcgatgctcg ccgagatcga gggcttcggc accgccctgg ccgagagcgg cggcgtcaac
    11521 ggcggcctgc acctggagac caccccggac gacgtcaccg agtgcgccgc cgacgtctcc
    11581 cagctcggca gtgtggggga ccggcacacc acgttctgcg acccgcggct caaccccgga
    11641 caggcgctgc gcatggtcac cggctgggcg cacaccctgc gctgagcccc gccgcgcccc
    11701 ggcaggcccc agggcctctc gtgtggatct tgccgggctc gcggggtccg gcctgatcca
    11761 aacgaaagac cctcagccct cccgccccga aaggagccga ctggtggtcg gcataccccg
    11821 tatcgcgccc tacgccctgc cggcggcgga cagcctcccg gcgaacaccg cccactggac
    11881 gccggacccg cagcgggcca cgctgctgat ccacgacatg cagcacttct tcctgcgctc
    11941 cgtccccgac ccgctgcgct ccgaactcgt cgacaacgcc gcccggttgc gcaaacgcgc
    12001 cgcgagcctc gcggtgccgg tggcctacac cgcgcagccg ggcggcatga gcgacgagga
    12061 ccggggactg ctcaaggact tctggggtcc gggcatgcgc accgcgcccg aggaccgcga
    12121 ggtggtgccc gaactcgccc ccgagcccgg ggactgggtg ctcaccaagt accgctacag
    12181 cgccttccac cgctccggcc tgctgcgccg gctgcgcgcc gccggacgcg accagctcgt
    12241 gctctgcggg gtctacgccc acatcggggt gctcgccacg gccgtcgagg cgttcaccaa
    12301 cgacatccag gtcttcctcg ccgccgacgc cgtcgccgac ttctccgccg aacggcaccg
    12361 cctcgccctg gagtacgtgg ccgagcgctg cggggtggtc ctgcccagcg cggaggtgtt
    12421 ccggtgagcc cgcccagcga cctcctgggc cgcctgctcg ccgcgcccgg cgaccaggac
    12481 ttcgccctgc tgcaccggcc ggagagcggc acccccggca tggtcgacgt cctgctgggc
    12541 gaggtctccc acccggccac gctcgccgga ctgccgctgc cggagggcag ggacaccccg
    12601 ggccacgaga ctctggtcct ggtgccctac cgccagctcg ccgaacggga cttcgccgcc
    12661 cccgacgacg gctcgcccct ggtcgcgctc accgtcaccg agcaggccga gctccccctc
    12721 gcggacgtgc tggagcggtt gcccgacacc ccggtcggca tgagcggcca ccgcttcgac
    12781 ctgtccgacg acgagtacgc cgagaaggtc cggcgggtcg tcgccgacga gatcggcacc
    12841 ggcgagggcg ccaacttcgt gctgcgccgc accctgctcg ccgacctcga cggctacacc
    12901 ccgcacaccg cgctggccgt cttccgccgg ctgaccgcgg tcgagcacag cgcctactgg
    12961 accttcgtca tccacgtcgg cgggcgttcc ttcgtcggcg ccaccccgga acggcacatc
    13021 tcggtgcgcc gggggcacgc cgtgatgaac ccgatcagcg gcacctaccg ctacccgccc
    13081 ggcggcgccg acctggccgg tctcaccgcg ttcctccagg accgcaagga gaccgacgag
    13141 ctgtacatgg tgctggacga ggaactgaag atgatgtccc gtatctgcga gcccggcgtc
    13201 cgggtcaccg gaccacggct caaggagatg gcccggctcg cccacaccga gtacttcatc
    13261 gagggccgca cccgccgcga cctgcgggac atcctccgcg agaccctctt cgcgcccacc
    13321 gtcaccggca gcccggtgga gagcgcggcc cgcgtcatcc agcgccacga gccccagggg
    13381 cgcggctact acagcggcct cgccgcgctg atcagccgcg agcccggcgg cggacgctcg
    13441 ctggactccg ccatcctgat ccgcaccgcc gacatcgccg ccgacggcag gctgcggctc
    13501 gcggtcggcg ccaccctcgt acgccattcc tccccccgcg cggaggccgc cgagacccgc
    13561 gcgaaggcgg ccgggttgct gcacgccctg ggcggcgcgg ccggcccgga cgtgcccccg
    13621 ctgccggcgg cgcgcttcgg ggaccggccc gaggtgcggg aggcgttgcg cggccggaac
    13681 gccgacatcg ccgacttctg gctcggtacc acgccccccg gcgccctccg ggtgcccgag
    13741 ctcaaggggc ggaagatcct ggtggtggac gccgaggacg ccttcaccgc gatgatcgtc
    13801 cagcagctcg aagcgctcgg tcccaccgcc gaggtgctgc gctacgaccg gctgcacggc
    13861 cgcctcgacg ggttcgacgc ggtcgtgatg ggccccggcc ccggcgaccc gcaggacacc
    13921 gccgacccga agatcgccgc ccttgacgcg gccgtggccc aactcctcgg cgaccggctg
    13981 ccgttcctcg cggtctgcct cagccatcag gtgctcagcc gccgcctcgg cctgccgctg
    14041 atccggcggg ccgaacccaa ccaggggctg cagcgcgcca tcgacctctt cggacggccc
    14101 gaacgcgtcg gctactacaa cacgttcgcc gccgtcagcc ccgccgaccg ccaccacgta
    14161 cccggcaccg gagaggtcgc ggtcagccgg gacccggaga ccggcgaggt cgacgcgctg
    14221 cgcgggccgc acttcgcctc cttccagttc cacgccgagt ccgtgctcac cgtcgacggg
    14281 ccccggttgc tcggggacgc cctgcggggg gtgctcgccc gatgaggctg gagatcgcct
    14341 ggtgggacct ggacgactcg ccccagagca tccgcaccct caacgcgcac ctgtcggagg
    14401 gggtgaccgg cgactgggcc ggggtgcccg gcctgaaggt gaagtactgg gtcgccgacc
    14461 aggcgcacaa ccgctggggc gccgtcatgg tgtgggagac cgaccgcccc gccggccagc
    14521 cgctgccgcc caaccgcgcc gccgacctga tcggccgccc cccggaccac cgcatgggct
    14581 tcgccgtcga ggccctcgcc gaccccaccg ccctcccgat tccccaggtc acccaggagc
    14641 cccgctgatg cacgagtacc tggtcgtgga cgccttctcc cgcaagccgc tgtacggcaa
    14701 cccggtcgcc gtcttcctgg acgccggcga cctgtccgcc gagacgatgc agcgcatcgc
    14761 gcgggagatg aacctctccg agaccacctt cgtccacccc gcccgcgacg gcggcgacgc
    14821 gcgcatccgc atcttcaccc cggtcaacga actgcccttc gccgggcacc cgttgctcgg
    14881 aacggcggtc gcgctcggcg aggtgcgggg gcgggaccgg ctgcggctgg agaccgccat
    14941 gggcaccatc cccgtcgaac tcggggacga cgacggcgcg gtgaccgtcc gcatgcggca
    15001 gccgcatccc gtctgggagc cgtacgagca cgccggggaa ctgctcgacg cgctcggcgt
    15061 cacccagacc gtcgccccgg tggagattta ccgcaacggg ccccggcacg tcttcgtcgg
    15121 gctggagagc gtcgccgcgc tctccgcgct caccccggac caccgcgccc tcgcccgctt
    15181 ccccgacatg gcggccaact gcttcgccgg ggagggctcg cactggcgga cccggatgtt
    15241 ctccccggcc tacggcgtcg tcgaggacgc cgcgaccggc tcggcggccg gccccctcgc
    15301 catccacctc gcccggcacg gcctcgccgc ctacgggcag ccgctggaga tcctccaggg
    15361 cgtggagatg ggccgtccct cgctgatgct cgccaccgcc gagggcaccg gggagcacat
    15421 cacctccgtc caggtcggcg gccacggcgt gaccgtcggg cgcggaaacc tctacgtcta
    15481 ggccggaccg actcaaggag ggcacggcat gaacagcagc aagttcgaga gcctcaccgg
    15541 ccgcaccgac cgcggcttcc cggagtacga cgacccgccg gccgagccgc tgggcctggt
    15601 gcgggcgtgg ctggcccagg ccgtggagca gggggtgcgc gagcccaggg cgctcgccct
    15661 ggccacggcc gacaagcgcg gccgcgcctc cacccgcgtc gtggtcttcg gcggcatcga
    15721 cgaccgggga ctgctgttca ccacccacag caccagccgc aagagccgcg acatcgagga
    15781 gaccggctgg gcctccgggc tgctctactg gcgcgagacc gctcagcaga tcagcatcgg
    15841 cggcccggcc gtccccatcg gcgaggccga ggcggacgcc ctctggcacg cccggcccgt
    15901 cccgctgcac gccatgtccg cggcgtccca gcagagcgag cccctcaccg accccgacgc
    15961 gctgcgcgcc gccgccgagt ccctcgccgc caccggcgcc gccctggccc gccccgcccg
    16021 gttcaccggc taccggctgg tcccgcacga ggtggagttc tggtcggccc gctccgaccg
    16081 gatgcaccac cggctgcgct acgagcgcga cggcgccgac tggcacgtca cccggctcca
    16141 gccgtgaccg cccccgacga caggagccga cccgccgtgc aggaacgcgc ctttcctctg
    16201 gtcttcgccg aacacgtccc ggcgaccgcc gccttctacg agcggctcgg cttcacccgg
    16261 ctgcggcaga acccgcccga gggcgagccc acgtacatcg ccctcgcccg gggcacggcg
    16321 gagctcgccg tggtctccac cgactggccc gccacccggt acgaccggcc gcccggcacc
    16381 ggggtccggt tcgagatgtt cgtcctcgtc gaggacctgg acaccctgct gaaggaactc
    16441 gccggggccg gcgtcccgtt gctgcgcgac cccgtggaga tgccgtgggg cgagcggatc
    16501 gcgtatgtca ccgaccccga cggcaacccc gtggccctcg ccgccggacc ccactcctga
    16561 ccaccacacc tgggacgcgc catgacgctg gacatcgccg agaccgaccg catcctcgaa
    16621 ccgccgcacg gcacccgccc cgacccggac gccttcgtcc aggcggccat ggcctggcac
    16681 ttcgaccccg acaccgggtc gccgttctgg ctcaagcggg ccaccgcctt cgacttcgac
    16741 ccccgccgcg acatccgcac ccacgccgac ctcgcccgct tccccaacgt cgccgccgaa
    16801 ctgcggcacg tgccggccgc cgacctcgtc ccgcgcggct acggtgaccg ccccgacgtg
    16861 atcggggtct acgagagcgg cggcaccacc ggcgccccca agcgcgtggt gctgctgcgg
    16921 gactggctgg agcgcaccct gcactggagc aacgaggcgc tcgacgcgca cggcttcccg
    16981 cgcggcgccg actggctcgg cctggtgccc ggcggcccgc acatcgtcgg cgagtacttc
    17041 cagcgctccg ccgcgaccca cggccggtac gggttccgtg tcgacctcga cccccgctgg
    17101 gtcaagcgca ccatcgccga gggccgggga cccgaggcgg gcgcctacgc cgagcacgtg
    17161 atcgaccagg ccgccgaggt actgcgcacc caggacatcg gggtcatgac catcaccccg
    17221 cccctgctgg agcggctggc ccgccgggac gacctggtcg acctcgtcaa cgacaaggtc
    17281 cgcgcgatcc gctggggcgg cacccagatg gacgccgact cccgtcacct gtaccgcacc
    17341 gaggtcttcc ccgacaccgt cctcagcggg aactacggca gcacgatgat cctcggcttc
    17401 gcgggggagc ggccgggcct gcccgacgac gcgccctgcg tcttcgacac cctcgacccc
    17461 tgggtcacct tcggcgtggt cgacccggag accggccggc ccgtccccta cggggagcgg
    17521 gggcgagtgg tcgcccacca cgtcagcaag tccttcctgc tgcccaacaa cctcgaacgc
    17581 gacctggcca cccgcgtccg gccgccggag ggcgggagcg gggactccgt cgccgacatc
    17641 gcgccggtcg gcgtcttcga gaacgagacg gtcatcgagg gggtctactg atgccgcccg
    17701 cgctggaaga ggaggagctg ccccagctcg acgcgctcgg gccgaggggc ccgtaccgcg
    17761 cccgcaaccg gctcacggtc accgatgtgt ccggagcgcc ggtcgcccag ctcagcctgg
    17821 taccgggggt gttcctgcac cgcgcgctga ccgcgctgcg ccgcgccgag cccgccaccc
    17881 ccgaccggcg ggccgccgta ctggcccgtg cggcggagct gttcaccacc ggccgggtgg
    17941 gcgggctgac cgtcaccgag cacgagcacc tcgtcagccg ggtcggcgga gtgcccctgg
    18001 gggtggtccg cacggcgacc cgcgccatcg gtgagcgcct cgcggccgcg tacgacagcg
    18061 cgcggcgggc ccggccggtg gacgcccgtg acgactggcg ggacccgctc acccgtgccg
    18121 ggcgcgcggt gtggacccgg cgcggcgagg tgttcgcggt gaacgcggcc ggcaaccacc
    18181 ccggcaccca cagcctctgg cccgaggcgc tggcactcgg cttccgggtc gccgtccgcc
    18241 cctcgcgccg ggagccgttc accccgtacc gcctgatcac cgcgctgcgc gaggccgggc
    18301 tcgggccgga ccaggtggcg ttcctgccca ccggccacga gctggccgac gagctgctgc
    18361 gcggcgccga tctcggcatg gtgtacggcg gcgacgacgc ggtccggcgc caccggaccg
    18421 acccggcggt gctgacccag gggccaggcc ggtccaagat cctggtcacc gccgacgtgg
    18481 actggcgcga gcacctggac accatcgtcg actcggtcag ccaccacggc ggcaccggct
    18541 gcgtcaacgc caccgccgtc ctcgtggagg gcgacccggc accgctgtgc gccgcgctcg
    18601 ccgaacggct cggcgcgctc cccgcgctcg cgccggagga cgacaaggcc gtacttccgg
    18661 tccaaccgct ggccaccgcc caggcgttcg gcgcccatct ggcgaaccgg gccgcgggca
    18721 cccggccctg gctgggcgcg gagggggtgg tggccgaact gggggacggc agcgcggcct
    18781 tgcggcccgc cgtgcaccag gtcgaccggc ccgacgcggc ccagctcggc gtcgaactgc
    18841 ccttcccctg cgtctgggtg gcgccctgga ctcccgacgc cggcacggcc gtcctgcggg
    18901 acagcctcgt cgtcaccgcc ctgaccaccc gggaggaact gatcgaccgg ctgctggacg
    18961 agcccaccat cggcaatgtc tacgtcggcg acacccccac ctaccgcatc gcgcccggac
    19021 tgccgcacga cggcttcctc ggcgacttcc tgatgcgcac caaggcggtc atccgcacct
    19081 gagccgccca ccaaccgacc tgccagaccg agcacttgtc gaagggacca ccacacccat
    19141 gcacgccgtt tcgtacaccg cacagtggat ggcagccgcc cgcgccctgg agtccgagcg
    19201 cgaggacgcc ctctacgtcg acccgctggc ccgcgacctc gccgagccca aggggttcga
    19261 gctgatcgac cgctatgtcg gcggcggtct gctgccgttc atctccatcc gcacccgctt
    19321 cctggacgac gcgatccgcg acctgctcgc ggacggctcg ataggccagg tcgtgctgat
    19381 cgccgcgggg atggacaccc gcgccttccg gctcgactgg cccgacgacg tcgacgtcta
    19441 cgaggtcgac cacggcccgc tcatcaccga gaagcggcgc cgcctggacg cgctgggcgc
    19501 caagccctcc gtcaagcgcc acgaggtgtc cgcggacctg accaaggagt ggctgcccga
    19561 cctggaggcg gccggcttcg accggacccg gcccacgctg tgggtcgccg aggcgctgac
    19621 cttcttcctc accgaggagc aggccgccgg gctgctgcgc ctgctggcct ccgcctccgc
    19681 gcccggcagc cacctcgcct tcgacatcct cggccgcacc ctgctccgca gccccttctc
    19741 caagccgttc ctcgaccggc tcgcggagga cggcacgccg tggatcttcg gcaccgacga
    19801 gccggagccg ttcctcgagg cgggcggctg ggaggtcgag tcgctgaagg agccgggcca
    19861 gcccggcgcc ggtgaggggc gctggccgta cgaggtccag ccgcgcgggc gccgcttcgc
    19921 caaccggctg tggctgatcc gcgcccggct cgccgcgcgg tgacgccggg tccctgagcg
    19981 catggcggcc ggaaccccgc ccagggggtt ccggcgccgc tcagtcccgc gcctggagcc
    20041 gctcccgcag ctccaggttc tcttccgcca gcatccgcat ccgctcccgg accggctcca
    20101 gcgcctcggc cagctccggc tccgagtagc gcggggtgat gtgcttgggg cagttccaga
    20161 acaggccctc cacccggatc agcatgagcc gctccagcgg gccgtcggtg cgcgggtcgg
    20221 acaaccgctc gtgcagttcg gggaactcgg ccggatcacg ggtctccgcg cggccgaaga
    20281 tcttcagccg ggtggggttg gcgtagtcca tgaagaacag cgagacccgg tcgtcggagc
    20341 ggaggttgcc cgcggtgatg tactgccggt tgccgcgcac ctccacccag gccagcgtgc
    20401 cgctgtccag cacgtgcacg aagcccggcg ggccgccccg gaactggacg tacggccagc
    20461 cg
//
