LOCUS       NZ_SHKU01000001        34670 bp    DNA     linear   CON 27-MAY-2024
DEFINITION  Streptomyces sp. BK022 Ga0307664_101, whole genome shotgun sequence.
ACCESSION   NZ_SHKU01000001
VERSION     NZ_SHKU01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. BK022
  ORGANISM  Streptomyces sp. BK022
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 1305487)
  AUTHORS   Kalluri,U.
  TITLE     Understanding the reciprocal impacts of modified plant cell wall and
            associated microbiome
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1305487)
  AUTHORS   Kalluri,U., Huntemann,M., Clum,A., Pillay,M., Palaniappan,K.,
            Varghese,N., Mikhailova,N., Stamatis,D., Reddy,T., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-FEB-2019) Prokaryotic Super Group, DOE Joint Genome
            Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.12.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 215.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004217355.1-RS_2024_05_27
            Annotation Date                   :: 05/27/2024 02:58:00
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,482
            CDSs (total)                      :: 6,401
            Genes (coding)                    :: 6,280
            CDSs (with protein)               :: 6,280
            Genes (RNA)                       :: 81
            rRNAs                             :: 5, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 16S)
            partial rRNAs                     :: 3, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 121
            CDSs (without protein)            :: 121
            Pseudo Genes (ambiguous residues) :: 0 of 121
            Pseudo Genes (frameshifted)       :: 49 of 121
            Pseudo Genes (incomplete)         :: 92 of 121
            Pseudo Genes (internal stop)      :: 16 of 121
            Pseudo Genes (multiple problems)  :: 29 of 121
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:05:10
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1076894
            Orig. end                         :: 1111564
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            SHKU01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..34670
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="8"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..34670
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..34670
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:24670](-)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..24670)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     gene            complement(818..1774)
                     /locus_tag="EV284_RS04905"
                     /old_locus_tag="EV284_0990"
     CDS             complement(818..1774)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004992367.1"
                     /locus_tag="EV284_RS04905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_0990"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_130330555.1"
                     /transl_table=11
                     /translation="MPSSRFRRVAVLVLEGAKPLDVGIPAQVFTTRASMPYEVRVCGAA
                     PGLVTGGDGLSYHVAHGLEALEWADVVFVPGYRFPDREEPPEPVVAALVAAHGRGARLA
                     AISTGAFALAATGLLDGRRATTHWHYARALAARHPLIRVDENVLFVDEGSVLTSAGAAS
                     GIDLCLHMLRGELGVAASNHAARRLVAAPYRSGGQAQYVPRSVPEPLGERFAATREWAL
                     HRLGEPLSLEALARHAAVSPRTFSRRFAEDTGYTPMQWVTRARVDLARELLERSEHSVQ
                     RIAHEVGLGTGTNLRLHFQRVLGTTPSEYRQTFARGE"
     misc_feature    complement(1839..1857)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 23.8"
                     /tool="antismash"
     gene            1883..4645
                     /locus_tag="EV284_RS04910"
                     /old_locus_tag="EV284_0991"
     CDS             1883..4645
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018957234.1"
                     /locus_tag="EV284_RS04910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_0991"
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_130330557.1"
                     /transl_table=11
                     /translation="MEFRLLGTVSVDTRRGPLPLGPAKRRSLLAALLLSANTPVPMGRL
                     TACLWDDEPPSQARGVIQGHVSRLRALLTEGDAEAYGVELLTAGDAYALRLPETLLDAQ
                     RFEELLTLAREQRDPADAVLMLGDALALWRGPALGGAFAGPPLQAAAHSLEESRLSAVE
                     QLALAYGRLGEHHRAAAVLRTEAVAHPLRESLSAALMTALYQAGRQSEALDWFHRTRRL
                     LADELGIDPGRELADAYGLILRGDPVPELLAARPKPTPKPEADPVRPPVPPRPALVPAE
                     AHADLLPRAPRGFHGRGAELAALGRAAAGEAPVCLVTGPAGVGKTALALWWAHRNADAF
                     PDGRLFADLHGFSDTGEPSVTEVLREFLLALGVPPRRIPESAPAAAALFRTLTDRLRLL
                     VVLDNARDSATVRTLLPGGADCVTVVTSRHRLEGLIASDAARPVPVGTLDAQDGTALLA
                     GVLGEERVLGEPVAARRLAELCGGLPLALRVTAARLAGRPQWSLAHLADELADERGRLA
                     HLAVDDTGVPAALRLTVQHLPGEAAHHFGRLGHHPGTHFDPYTAAALAGTDPPAAARAL
                     ERLGAAHLVTETAPGRWELHDLVRLYARDLDPATGPTALTGALDHYIATALAAAETAQP
                     GGEPCFALPEDFRRPSAVRDFADRAEAMDWLAAEREDLARAVTAARAAGLDDRAWRIIL
                     LQWPQVVWRSRDNWVPLLYTALECAQAVDDPYAESRVRTLLGWVLSEEGRLVDALTLLE
                     PSPALARRTADRLGEATALVNLAVVQSAQGDLNAALANCARAATLAREEGNPHTEMLAL
                     LHLSRTHLSSGDPDRALHVARTALDLGPEHEEAARTSLLHTVSGEAHLALGNKTEALHL
                     LERAADEAESTGYDEGAVRALEALLRVSGRADHRKRHEEAVRRLAGEDR"
     gene            4671..5057
                     /locus_tag="EV284_RS04915"
                     /old_locus_tag="EV284_0992"
     CDS             4671..5057
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014139639.1"
                     /locus_tag="EV284_RS04915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_0992"
                     /product="hypothetical protein"
                     /protein_id="WP_130330559.1"
                     /transl_table=11
                     /translation="MCRYAVTPYKLHYACLPCRVSFKRHADREHACPNCARPLVCAGRD
                     FAPPRRRDVAGWSVVAAVLGEGLRFDGRSGCGCAKEPKYRPRTRAELRVRRIVALREGV
                     PPAEVLGRVDPLDGGGPGPASEGR"
     misc_feature    5166..5179
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.44"
                     /tool="antismash"
     misc_feature    complement(5166..5181)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.0"
                     /tool="antismash"
     gene            5176..5868
                     /locus_tag="EV284_RS04920"
                     /old_locus_tag="EV284_0993"
     CDS             5176..5868
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669670.1"
                     /locus_tag="EV284_RS04920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_0993"
                     /product="DUF4232 domain-containing protein"
                     /protein_id="WP_130330561.1"
                     /transl_table=11
                     /translation="MNASRRTALFSVAASAALALSLTACQSGEGTKAEGAAPVAGDTVS
                     ASASAAASAPAAGAGTGGDTGSGTGTAVGTAHKSGATSSGAKKGTATPLCRAQDVKVSS
                     ERQDGPPYTHIILTARNTSGHRCEMAGFPHIQFLESHKQDVPSVAKSKPAVPTVLNPGD
                     PAFVLVKLSDGGVDEDNEVVNAFQLVLEGDSAVIAVDSSAGGGLAVDPAKTLTGYWTTE
                     LRNGADDF"
     regulatory      5945..6077
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            6116..6337
                     /locus_tag="EV284_RS04925"
                     /old_locus_tag="EV284_0994"
     CDS             6116..6337
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014045240.1"
                     /locus_tag="EV284_RS04925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_0994"
                     /product="CbtB-domain containing protein"
                     /protein_id="WP_130330563.1"
                     /transl_table=11
                     /translation="MAQTVAQPTAGNPAAPATLPLKEIAPWAVFFGVLMLVLLYFVGAE
                     QGATSVFNGTDVHEWVHDARHLLGFPCH"
     gene            6359..7114
                     /locus_tag="EV284_RS04930"
                     /old_locus_tag="EV284_0995"
     CDS             6359..7114
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009192299.1"
                     /locus_tag="EV284_RS04930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_0995"
                     /product="CbtA family protein"
                     /protein_id="WP_130330565.1"
                     /transl_table=11
                     /translation="MNSATVRNLLVRGMLAGLGAGVLALVAAYFLGEPNVDSAISFEGH
                     HAHEHEVEVVSRSLQSTAGLATGVLVYGVAFGGIAALAYCFALGRVGRFGPRASALLLS
                     GTALLAVYVVPFLKYPANPPSVGDPDTIGKRTTLYFLMMLLSVLLAIGATLLGKRLAPR
                     LGNWYATLVAVAAFALLTGLAYAFLPVVNEVPEHFPATLLWRFRLSALAIQTVLWAGFG
                     LLFGELAERLLNPRPAAARGTGQAVAASH"
     gene            complement(7164..7733)
                     /locus_tag="EV284_RS04935"
                     /old_locus_tag="EV284_0996"
     CDS             complement(7164..7733)
                     /EC_number="3.1.3.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1101: phosphoglycerate mutase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020130746.1"
                     /locus_tag="EV284_RS04935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_0996"
                     /product="histidine phosphatase family protein"
                     /protein_id="WP_130330567.1"
                     /transl_table=11
                     /translation="MSSRLVLVSPAIGPALREARFYDGSSSVDQGGAARARAAAKALPE
                     AARVMVSPGARCRDTAEALGLRGAVAAELAPLDAGRWRGRALAEVGAAEGEALARWLRD
                     PEYPAPGGESVRQVCARVGRWLESVPEGRTVAVVEPEVVRAAVVHALGLPTGAFWRLDV
                     APLTATELSGRAGRWNLRLGHAVGGG"
     gene            complement(7810..>8088)
                     /locus_tag="EV284_RS04940"
                     /old_locus_tag="EV284_0997"
                     /pseudo=""
     CDS             complement(7810..>8088)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011027494.1"
                     /locus_tag="EV284_RS04940"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_0997"
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /pseudo=""
                     /transl_table=11
                     /translation="LEAARSHMRVARELAVHGYPREGGPGVYDIHSPGVPSAEEAAELL
                     RTGLKAIPAERLWVNPDCGLKTRAWPETRASLGNLVAAARTVRGELR"
     gene            complement(8203..9531)
                     /locus_tag="EV284_RS04945"
                     /old_locus_tag="EV284_0998"
     CDS             complement(8203..9531)
                     /GO_function="GO:0004180 - carboxypeptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1244: amidohydrolase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018548796.1"
                     /locus_tag="EV284_RS04945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_0998"
                     /product="amidohydrolase"
                     /protein_id="WP_242625567.1"
                     /transl_table=11
                     /translation="MSSDQSRPSVTAAGGAPPGLDALLPSTAELYLDLHRHPELSGAEE
                     RTAARFADRLTTDGFRVLRGVGGHGVAAELPNGDGPAVLLRAELDALPVAEETGVPYAS
                     TATAPGPDGRPVPVMHACGHDAHLACAAAAARWLAEHRDRWRGTLLVVGQPAEETLSGA
                     RAMLEDGLYDRITAPDVVLAQHTAAFPAGMVAHADGPLMAGSVTLEVVFEGDGGHAATP
                     HLTADPLLAAAGAVTRFPAVAARETDPAERLLVTASSLRAGDTGRTGNVIATRAELRVT
                     VRALSEAALVRGAAAVERVVRAEAASAATAPRVTVRELARSGVTRPDPGVTAAVRAAHQ
                     AAFGAARVTGWPASSATEDFPLLTGAGGHLHGRPGIRGAYWMLGSVGPTQWAAAPGDGP
                     AEKFRGLPHNHSPRYLPSVRLTLGTGTAALVTAALAQLDPAAA"
     gene            9717..9890
                     /locus_tag="EV284_RS04950"
                     /old_locus_tag="EV284_0999"
     CDS             9717..9890
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003968635.1"
                     /locus_tag="EV284_RS04950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_0999"
                     /product="thiazolylpeptide-type bacteriocin"
                     /protein_id="WP_031179489.1"
                     /transl_table=11
                     /translation="MADNTLASLAQEILDLESETFEITDYSDASEVMLGSSTSCSSTST
                     CSSTTSTTSCTA"
     gene            complement(10001..11938)
                     /locus_tag="EV284_RS04955"
                     /old_locus_tag="EV284_1000"
     CDS             complement(10001..11938)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018548798.1"
                     /locus_tag="EV284_RS04955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_1000"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_207228910.1"
                     /sec_met_domain="YcaO (E-value: 4e-74, bitscore: 246.4,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 1.6e-102, bitscore:
                     339.3, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTTTPLEAARADLHSRLAARATAAGLHTPAVSRIGDTNVLGEG
                     GSGLPAEPATVHLTAQAVLLGPWGGTPAAGPACGTCLAMRRQRLRTRTEREALETGTGT
                     TAAGAWPVLPDHTVDAVWSLHRLIASGAARHTAEGPDAELPRVTEVDLETLRVRTFPLL
                     PEPTCPRCRPFTEEAASRAAAEATLPAPAPLPKPRPDSYRLRRASDHPLPVKALANPVC
                     GVLGGGTWIDVTSPTTAPVAGSVFMRGYAGLTDVTWSGQANSFADSRDLAFLEGLERYA
                     GTHRRHRAPVVTASLEELGDRALDPRACGLYGPRTYAEDPMVEPFDPARPIPWVTGWSL
                     RDGRPVLVPARLVYYSAGTAADNFVFECSNGCATGSSWEEAVFFGLLELIERDAFLLGW
                     YGDLPLPEIDLDSVRSPGVRAMVARAALQGYDVHVFDNRVDLPVPVVTGLAVRRDDAPG
                     SLAFAAGASFDPETAVESAVSEILTYIPHLPGQVAERPTELAAMAEDFDLVKRLPDHAA
                     LFGLPAMRVHATGYLKPPRTAPLDELFAGWEERRPRTGDLRDDLLLVRDLLGEAGCEVI
                     AVDQTTPEQRRMGLRTVATLAPGLLPIDFGWLRQRALTLPRLRTAPYRAGMVPAPLGEE
                     ELRRVPHPFP"
     gene            complement(11935..12687)
                     /locus_tag="EV284_RS04960"
                     /old_locus_tag="EV284_1001"
     CDS             complement(11935..12687)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015609025.1"
                     /locus_tag="EV284_RS04960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_1001"
                     /product="ABC transporter permease"
                     /protein_id="WP_130330569.1"
                     /transl_table=11
                     /translation="MSAYAALTRATYVASVRDKTTLFFTFAFPLAFLVLFGLIFQGDKV
                     DGGLASINYIAPGVLSWGVGNAAVFSVGFALMQWRRDDLLRLIWRTPTPLRTLLASRWT
                     VAMGVALTQTVLFTAVALLPFFGLRLMGPWWAALPLLVLGVTAFLAMGLVVGSLADTPE
                     AVAAIANLVMVPMAFLSGSFFPDDLMPSWLRTAAKVLPLHYLNDGLTDAMGGRGDLGDI
                     ALDCAGLAVFALVFGVVATRIFRWSNRT"
     gene            complement(12684..13640)
                     /locus_tag="EV284_RS04965"
     CDS             complement(12684..13640)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019890992.1"
                     /locus_tag="EV284_RS04965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_130331120.1"
                     /transl_table=11
                     /translation="MSAPESRTEAAPRGTTTETVVALDGVSKRYGEVTALDGVSLEVRH
                     GEFFGILGPNGAGKTTLVEIVEGMREADSGTVTVFGQSPWPRDIALLARIGVQTQASAF
                     FARLTAAEHLRTVAALYGMAPEAARTALERVGLTEKADARIDHLSGGQRQRLAVATALL
                     NEPELIFLDEPTAALDPEARRELWELLRSLRSEGRTIICTTHYLDEAEALCDRVAIIAG
                     GRVVALDSPRSLIRALAAPTRLLVPADKVSPKAALALAGVDRATVRGADLVIETAVPNR
                     VLPALGDLVDIDAVSVRTPTLEDAYLSLTGTGSEHHR"
     misc_feature    14389..14404
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.97"
                     /tool="antismash"
     gene            complement(14942..16060)
                     /locus_tag="EV284_RS04970"
                     /old_locus_tag="EV284_1003"
     CDS             complement(14942..16060)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017948539.1"
                     /locus_tag="EV284_RS04970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_1003"
                     /product="lantibiotic dehydratase C-terminal
                     domain-containing protein"
                     /protein_id="WP_130330571.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 3.7e-100,
                     bitscore: 331.6, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTAPTEASALPGRAPGEWLAVHVFYAASPRPLLVQCVRPLVDAL
                     TEEGLLAGYFFINYWLEGPHLRLRLKPVRAADAPVVRERAHAALETFLRERPALYEVKD
                     GFFADLYETLFALEFGEEERAGYLGPDGRMVLRPNNSFEDRPYEPEYGKYGGPAGTELA
                     EWHFQHSSDLVIEAARSMNLHLRTVLLGLSAQLMTVMAGTFLRDDEALLSFLDRYHTFW
                     NRAFSTTNYTADDGYDRAYSAMGTSLPGRFRDIRAAVAAGGTGRLPAFLRGWAGHCAEL
                     RDRATALTRDGELVFRSWDGTRDLRPTDPAQSLPMLLSPYLHMTNNRLSTTVRDEAFLS
                     YVLARALRDGGARGAGAGAGDSLAGWRPGGEG"
     gene            complement(16057..18789)
                     /locus_tag="EV284_RS04975"
                     /old_locus_tag="EV284_1004"
     CDS             complement(16057..18789)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018548802.1"
                     /locus_tag="EV284_RS04975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_1004"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_130330573.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.4e-50, bitscore:
                     168.2, seeds: 73, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPATTAADTTVTLHRRFMLRVAGLPAETVSALRAPETADWAARA
                     AAEEDRLRALGARLSDPLSAAVGATEDAALRRRLLALRRQVFNNRLPADLPAARALASG
                     LGGGTGADLTAWLNARRRWEELRAEGETVLGGALARTRAALRGLALDDRLRRGLLLASP
                     TLEERLDAFAADRSPAPGKRARKMERSLLSYLYRTACKTSPFSTLTGVALGGFGEGGDL
                     TEVGDGWTSHPRLNVVVLTRLAELIVADPARRADLPVAPASGWTRDDDRVRFVRRAVTA
                     GDDSAPVSFDAAQDRLFFLRRQGALDGMLTLLRDTGGTLTHGDLARWLGATTGAGEEEA
                     GHYLTALRELGMLQLPLLDTGVHSPDPLRAFQRALRSLGVEWADTVAARLDGPAEAVAR
                     YGDADVPTRRALLAGLRTDLTALQAELGAERAVLPRTLLYEDVSAGTTGAPLAEWAEPV
                     AAPLRSIGRVLPAFDVALPQRLTLKGFFVARYGRGGRCEDLLRLVHDFHEDIFRQYLQF
                     TAAKDGHLPDGSHAPEENWLGVPEITSIDRARATLTARMRKRWAELPPDAVEFVLDDAT
                     VDEMAEALGTAAPAFRPQSHFVQLARRADGPLAVLNNSYGGLCFPFTRFTHCFDGAGGP
                     GLTDTLRDGLRSVLPPGAVLAEVTAGAATTNLNLHGRLTDYEIVCPGENSTAPGQARLH
                     LDDLYAVHDETEDRLLLRSRRLDREVVPVYLGYLVPMVLPEIPRTLLLFSPTSRSVPDV
                     WRGVPAGEATDGVTRRPRVRHHALVLQRRSWTVADGHLPLRAPGTTDADWYLAWHRWRV
                     RHGLPARVFATVHEETGGDRGAAWSGGSKPQYVDFESPLSLTALEGLLAGKQARTVFEE
                     MLPAEDELHVTSPRGRHVAELAVELLPVAAARTEEDATR"
     gene            complement(18854..20440)
                     /locus_tag="EV284_RS04980"
                     /old_locus_tag="EV284_1005"
     CDS             complement(18854..20440)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010059793.1"
                     /locus_tag="EV284_RS04980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_1005"
                     /product="nitroreductase family protein"
                     /protein_id="WP_130330575.1"
                     /sec_met_domain="PF00881 (E-value: 6.6e-09, bitscore: 32.2,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGYAHEYATAVMRRGRTPMEPADFVPDWADRPRKGKYFPGVPSFP
                     LPDGGCADDATLGRGLFGEPGTGAFTLPLLGAMLRDSYGLTGRRLAVQANTDLGSLPFH
                     THANWSRGTASGGGLYPIGVHWVSGASGPLTPGVYYYDTPHHRLNRLLSGDVTGEVRSA
                     LGDLAEADTDQFLVLGVTFWQNAFKYNSFSYHAVTMDIGALLETWRMWARAHGLRLDTA
                     LWFDEPRVGRLLGLDPAEDGVFAVVPLRWDAPAPEAAAPETPGAAVRRVPDERSRRTLA
                     FPTLARVHEATLEGAADRPAPGRLDPALAAAAGDGERVPLPDPAPLDTTVRRALRERRS
                     SFGRFSAGEPLDPAKLSVTLAAAVTAATLDSDVETPGAPPLTRFHVFVNHVRDVPPGLY
                     EYDRDTGGLVLLKPGGFGAFLQENYFLANYNLEQAAAVLVPVARTYAVLDAVGDRGLRL
                     VNAAVGAIAQAVYTAASAAGTGCGVALGFDCVSYAEEFGVAGRGEVPLLIMMIGEERPR
                     PADYRYDIVAP"
     gene            complement(20533..22449)
                     /locus_tag="EV284_RS04985"
                     /old_locus_tag="EV284_1006"
     CDS             complement(20533..22449)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018548804.1"
                     /locus_tag="EV284_RS04985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_1006"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_130330577.1"
                     /sec_met_domain="TIGR03604 (E-value: 1.9e-90, bitscore:
                     299.5, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="YcaO (E-value: 5.4e-74, bitscore: 246.0,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTETEAAPAAVDAPWDRVCEELTSALACRVPGRAAAVRALGVRD
                     QLGDAVVEFPPGVIPVGLYGHHAVVGPVAPVGGRGCPGCLARRWQAVRAGFLRDALEQG
                     GPTLATGTPPWEAGFVVDALAALVSAADAHPRAPRHPWVWLLDLETLRVARFPLVPDGE
                     CPACADRPDDTAEGARIALEPAPEHAPGSFRTRPLSAYDLPLEAFANPVTGMLGPLVAP
                     DLTSASTSSAVGAFTTRSGAYLRECYWGGHTGAYGTSVRVGLLEGLERYAGMRARARRP
                     VVTATLEELGDTAVDPRISGLYPDTFDAEAVGAPRFAPDRPVRWVWGWSLRDDRPVLVP
                     EVVAYYHAPGGIRRRFVQESSNGCASGGSPAEAVHHGLMETIERDAFLLAWFGRARLPE
                     IDPASSTRPATRAMVDRLAMYGYRARFFDTRVSFPVPVVTAVAERVDGGPGLLCFGAGA
                     SPDPEDALAGGLCEIATDAVNLRRRTAREERRLRRMAADFDEVRVLHDHPLLYGLPEMG
                     RYTDFLLRGRDDGDRVPLASLAPDRPRSRPADLRADVEAVVAEVTARGFDVVVVDQTAP
                     EQRGLGLSTAKVLVPGLLPIDFGWSRQRGPWLPRTRTALREAGLRTADLPPDECNPAPH
                     PFP"
     gene            complement(22439..24670)
                     /locus_tag="EV284_RS04990"
                     /old_locus_tag="EV284_1007"
     CDS             complement(22439..24670)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Heterocycloanthracin_C_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thiopeptide_F_RRE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018105667.1"
                     /locus_tag="EV284_RS04990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_1007"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_130330579.1"
                     /sec_met_domain="Heterocycloanthracin_C_RRE (E-value:
                     2.4e-11, bitscore: 39.5, seeds: 5, tool:
                     rule-based-clusters)"
                     /sec_met_domain="Thiopeptide_F_RRE (E-value: 1.3e-17,
                     bitscore: 59.7, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="YcaO (E-value: 3.8e-18, bitscore: 62.4,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPAPSSHEEIARSRPRIRRDVLFTRTPDGVLFHNAHGGFNVVTQ
                     SAYRFAALIVPHLDGERRVEELCAGLGDKQRDMVVRLVGALYARGFARDAGPRPTGDTL
                     SPQVAARFAHQLDYLDHYADDAHGRFARFRDTRVAVLGDDETARWAALGLLRNGCATVA
                     VTVEDAAEGALDHEPSGTAGLDAEVAGLTEAGCAPTLTRLAGSTPGWADLDGWDTVLVT
                     GANAPARLLRLLTEGVPEGRRLLGAWTFGERAVVGPVMTAGTPGCWSCAALRLGAGSDA
                     ADSADLWSGLGPAAPLETPARVPTGPLAGMLGNLLSFEVFRLVTEALPAETRNQVIVQD
                     LNSLDVLAEPLLPHPRCRFCASGEPKAPDGAALRVPHADDEPVALPADGPADEAAAKGA
                     LAALEPRDVLVREAAGVFGGYADDDWEQTPLKVSTVRLGVSPGRVREVSAIDVHHVAGA
                     RLAALFRGAEVYAEQVVPPRVGGEGSRIAPAELALSSGLQVPVDRVSAWSEATSLLDGR
                     TVLVPTGAVRTLSGWNDQGLFERSSAGTGAAGTPRAALARALRSALAHDALRRVVRRAA
                     PARLVDLDSLTADAELLFLLRSAENLGVTVEVLDLTGAGATALPVALARSTDPESGAVR
                     WAPGSGLRPREAVLEALRDLLGAEQMRRAGAEPDLGDPLWADLEAAALVPEGEPVSLRA
                     DGTGWAEVLDALAAAGRDAFAVPVAAPDLAAGEIHAVRVLLTRGGPGAH"
     aSDomain        complement(24386..24634)
                     /aSDomain="Heterocycloanthracin_C_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing C protein in a
                     heterocycloanthracin LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_EV284_RS04990_Heterocycloanthracin_C_
                     RRE.1"
                     /evalue="5.80E-13"
                     /identifier="RREFam011.1"
                     /label="EV284_RS04990"
                     /locus_tag="EV284_RS04990"
                     /protein_end="95"
                     /protein_start="12"
                     /score="39.5"
                     /tool="antismash"
                     /translation="RSRPRIRRDVLFTRTPDGVLFHNAHGGFNVVTQSAYRFAALIVPH
                     LDGERRVEELCAGLGDKQRDMVVRLVGALYARGFARDA"
     aSDomain        complement(24395..24631)
                     /aSDomain="Thiopeptide_F_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing F protein in a thiopeptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_EV284_RS04990_Thiopeptide_F_RRE.1"
                     /evalue="3.20E-19"
                     /identifier="RREFam004.1"
                     /label="EV284_RS04990"
                     /locus_tag="EV284_RS04990"
                     /protein_end="92"
                     /protein_start="13"
                     /score="59.7"
                     /tool="antismash"
                     /translation="SRPRIRRDVLFTRTPDGVLFHNAHGGFNVVTQSAYRFAALIVPHL
                     DGERRVEELCAGLGDKQRDMVVRLVGALYARGFA"
     gene            complement(24701..25789)
                     /locus_tag="EV284_RS04995"
                     /old_locus_tag="EV284_1008"
     CDS             complement(24701..25789)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF015649.4"
                     /locus_tag="EV284_RS04995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_1008"
                     /product="AfsR/SARP family transcriptional regulator"
                     /protein_id="WP_130330581.1"
                     /transl_table=11
                     /translation="MRKAVVKTGLPAPHGALPDQQATAAHPGRPRFQVLGLLAITDGHE
                     TVVLQPSKPTSLLAALLLHPGAVVSGELLQRVVWGDRPPSGGRSALHTCVLRLRRLFSK
                     YGVADHAIEAVPGGYRLQADAESLDLLHFRDLLGRASAGDDPEAALRLARAALGLWKGP
                     LLGNVHSDELHRDHVPRLAEERLLAVERVFDGELRLGRHREMIAEAREAVRGQPGHEGL
                     SALLIEALYRSGRRAEALAEYRRIHAHLTSELGVEPGAALRALQLAVLRGEPYGGRPAL
                     PAAGVPPSRAAGASSALERASPPAPGALVLRALVDAGLLEEDPSGRYRVHDLLRLFVQA
                     AGTSLPATAPHDPAETSPPPAD"
     gene            26059..26250
                     /locus_tag="EV284_RS05000"
                     /old_locus_tag="EV284_1009"
     CDS             26059..26250
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018548806.1"
                     /locus_tag="EV284_RS05000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_1009"
                     /product="hypothetical protein"
                     /protein_id="WP_130330583.1"
                     /transl_table=11
                     /translation="MPWWALVPVVSMITGPLVLYVLSRRKRDSDDDVERYEELSHKYEE
                     LRAENRRLEPPAAGDQRG"
     gene            complement(26272..27249)
                     /locus_tag="EV284_RS05005"
                     /old_locus_tag="EV284_1010"
     CDS             complement(26272..27249)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008407685.1"
                     /locus_tag="EV284_RS05005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_1010"
                     /product="DUF5996 family protein"
                     /protein_id="WP_130330585.1"
                     /transl_table=11
                     /translation="MSERPEAWPVLDHAELGPMLEYVNRVVQVAGKYSLDDPFEVGWGN
                     IVLEVSPRGLRTPTFRRNGVTFTVHYRLLDGDVVIETDRAARTLSLGRTSVADFFASFC
                     EAATELGIPHPRSARICEIPAAPPNFEDDRTERVWDAHSARLIWEAFDLAAGGLEAWQA
                     PFLGHRPRVGVMWGGFDLSATRWRPERTDPGPEGPPFMRNAQLHEYVSVGFSFDNTHGD
                     GSSPLDIGMYAYIWPQPDGLAGRSWGVEGADWHPDLGLALLPWQNLRRLPDPHGAIVRF
                     GDAVYEAAVRTAGWPADLVGPRVDGWYMSEHQPSEHAERVGQRG"
     gene            27528..28634
                     /locus_tag="EV284_RS05010"
                     /old_locus_tag="EV284_1011"
     CDS             27528..28634
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1251: luciferase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019061307.1"
                     /locus_tag="EV284_RS05010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_1011"
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="WP_130331122.1"
                     /transl_table=11
                     /translation="MQFGIFTVGDVTPDPTTGHTPTEAERIQATVAIARKAEEVGLDVF
                     ATGEHHNPPFVPSSPTTLLAYIAAQTERIILSTSTTLITTSDPVKIAEDFSVLQHLSGG
                     RTDLMLGRGNTGPVYPWFGQDIRQAIPLTVENYGLLRRLWREETVDWEGTFRSALQGFT
                     LVPRPLDDVPPFVWHASIRTPEIAELAAYFGDGFFANHIFWPASHTRQLVSLYRRRFAH
                     YDHGTPEQAIVGLGGQVFMRPNSQDAVKEFRPYFDNAPVYGHGPSLEEFTRQTPLTVGS
                     PAEVIEKTLGFRAYVGDYQRQLFLIDHAGLPVKTVLEQLDLLGEEVVPVLRREFAEGRP
                     EGTPAAPTHASRLRAREDATDEGDTEAR"
     gene            28631..29236
                     /locus_tag="EV284_RS05015"
                     /old_locus_tag="EV284_1012"
     CDS             28631..29236
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018548810.1"
                     /locus_tag="EV284_RS05015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_1012"
                     /product="CE1759 family FMN reductase"
                     /protein_id="WP_130330587.1"
                     /transl_table=11
                     /translation="MKITIITGGLREPSSTRLLADRLAAAVTRELEAGGEPVELSFVEL
                     RPLAHPIMDAMLTGFTGEALDTAFETIAGADGVIAVTPAFNASFSGLFKSFFDVLPEET
                     LSDMPVLIAASGGTERHSLVLEHALRPMFSYLHAIVSPRPVYAATSDFGTQDGASLGAR
                     INAAATDFARLLRACGPRTRETQEDADLATMRGLLGGS"
     gene            29400..31259
                     /locus_tag="EV284_RS05020"
                     /old_locus_tag="EV284_1013"
     CDS             29400..31259
                     /GO_function="GO:0046556 - alpha-L-arabinofuranosidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0031221 - arabinan metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018548811.1"
                     /locus_tag="EV284_RS05020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_1013"
                     /product="arabinofuranosidase catalytic domain-containing
                     protein"
                     /protein_id="WP_130330588.1"
                     /transl_table=11
                     /translation="MRAIRSAVLPGLRGRFGALVSVLALLLGALAGLSAPAQAAGSAPC
                     DIYAAAGTPCVAAHSTIRALFAGYNGPLYRVTRASDGAATDIGLLTAGGYADAGRQDTF
                     CGGTTCRMTKIYDQTSRHNDLNPGPAGTAGMGADRAADASELAVTAGGHKVYGIWISPG
                     VGYRSNGAASGVAVNGQPEGVYMVASGTHVGSACCFDYGNAERTPADTGNGHMDAVSIA
                     TTCYFAPCTGNGPWVEADLENGMFQGDNGSNPANRGNSSTYVTAVLKNDGQTRYALKGG
                     NSQSGSLSTWWDGALPSRGGYRPMQQEGGIILGTGGDNSNWNMGTFFEGAMVSGYPSDA
                     AENAVQANVVAAGYSGQTNVPNGPQGTITGPGGKCVDVAADDTGVNGAAVQLWDCQTYA
                     EDQHWTHNPDTSLGTISRCLDINGNGTANGTEVELWDCDGVGGQKWVQQADGSLRNPQS
                     GRCLDAPNGTSANGTRLRIWDCNGSAAQKFSVNGGAPIAAPGAKCVDVAADDTGVNGTA
                     VQLWDCQTWSVDQHWFHRSDSSLSTLGRCLDVNGNGTAGGTEVELWDCNGAGGQKWEQQ
                     ADGSLRNPQSGRCLDAPNGTTGNGTRLRIWDCNGSAAQKFQLN"
     misc_feature    29424..29426
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    31574..31588
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.56"
                     /tool="antismash"
     gene            31577..32371
                     /locus_tag="EV284_RS05025"
                     /old_locus_tag="EV284_1014"
     CDS             31577..32371
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (8-144). E-value: 7e-10. Score:
                     31.0. Matches aSDomain:
                     nrpspksdomains_EV284_RS05025_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004979307.1"
                     /locus_tag="EV284_RS05025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_1014"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_130330590.1"
                     /transl_table=11
                     /translation="MHLDLSGRTALVTGSTQGIGAAIALGLARAGARVAVNGRDRERVS
                     ASIAEFATQAPDAEFVAAAADVSTEEGARQLLRELPQVDILVNNLGIFGTADPLELTDD
                     EWRRYFEINVLAAVRLTRLYLPGMTDRGWGRVLYIASDSAIVIPAEMIQYGMSKTALLA
                     VGRGFAKKAAGTGVTVNSVIAGPTHTAGVEDFVYQLVDKDLPWDEAQRVFMRDHRPQSL
                     IQRLIEPEEIANMVVYLSSPQASATTGGALRVDGGYVDAILP"
     aSDomain        31601..32008
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EV284_RS05025_PKS_KR.1"
                     /evalue="7.00E-10"
                     /label="EV284_RS05025_PKS_KR.1"
                     /locus_tag="EV284_RS05025"
                     /protein_end="144"
                     /protein_start="8"
                     /score="31.0"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TALVTGSTQGIGAAIALGLARAGARVAVNGRDRERVSASIAEFAT
                     QAPDAEFVAAAADVSTEEGARQLLRELPQVDILVNNLGIFGTADPLELTDDEWRRYFEI
                     NVLAAVRLTRLYLPGMTDRGWGRVLYIASDSA"
     CDS_motif       31607..31693
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EV284_RS05025_0001"
                     /evalue="8.60E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="EV284_RS05025"
                     /protein_end="39"
                     /protein_start="10"
                     /score="15.2"
                     /tool="antismash"
                     /translation="LVTGSTQGIGAAIALGLARAGARVAVNGR"
     gene            complement(32347..32910)
                     /locus_tag="EV284_RS05030"
                     /old_locus_tag="EV284_1015"
     CDS             complement(32347..32910)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009192709.1"
                     /locus_tag="EV284_RS05030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_1015"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_242625568.1"
                     /transl_table=11
                     /translation="MIRGDALLLRPWRAADAAELVRVQRGDAALRRWTGAAVDDEAGAL
                     AWIAGQARGWETGDRLGFAVVAAGSPGTPCSPDAEGELLGHITLKDVVPGDGRAEVGYW
                     TAARARGRGVAPRALTALTGWAFGRGLTRLELLHQMDNTASCRVAVKCGFERAGVLPAA
                     PPEFPLDGCLHARLRDGQGRMAST"
     misc_feature    34050..34065
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.86"
                     /tool="antismash"
     misc_feature    34333..34348
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.33"
                     /tool="antismash"
ORIGIN
        1 gatcgagccg accggcaccg ggacccggat cgagtcgccc gacagcttgc cgtcgaggtt
       61 cggcagcacc aggccgatcg ccttggccgc gcccgtggtc gtcggcacga tgttcacccc
      121 ggccgcgcgc gcccggcggg gatcgcggtg cgggccgtcc tggaggttct gctcctgggt
      181 gtaggcgtgc acggtcgtca tgaacccgtg ctcgatgccc gccagctcgt ccagcacggc
      241 ggccagtggg gccagcgcgt tggtcgtgca ggaggcgtta gacacgatgg tgtgcagcgc
      301 cgggtcgtag gtgtcgctgt tcaccccgta cgccagcgtc acgtcggcgc cgtccgaggg
      361 ggcgctcacc agcacccgcc ccgcgcccgc gtcgaggtgg gcgcgggctg ccttcgccga
      421 ggtgaagcgg ccggtcgcct ccagcacgat gtcgacgtcc agctcgcccc aggggagctg
      481 ggccggctcc cgctcggcga ggaccttgat acggcggccg tcgaccacga gggtgtcgcc
      541 gtccacctcc accggacggc cgagccgccc ggccgtcgag tcgaaggcca gcagccgggc
      601 cagccccgcg ggttcggtga ggtcgttcac cgcgacgacc tcgaggtcac tgtcgcgttc
      661 gagcagagcc cgcagcacgt tgcgtccgat gcggccgaat ccgttgatgg cgatgcgcgt
      721 catgaatggt gtcccttccg tccgccccca ggttcgcgga cgggggccgg gcgcggcagt
      781 ggcaggagcg ccatggtgcg caaggatcac gccagggtca ctcgccccgc gcgaacgtct
      841 gccggtactc gctcggcgtg gtcccgagca cgcgctggaa gtgcagccgg aggttggtgc
      901 cggtgccgag cccgacctcg tgggcgattc tctgcacgct gtgctccgac cgttccagca
      961 gctcgcgcgc caggtcgacc cgcgcccggg tcacccactg catcggcgtg tacccggtgt
     1021 cctccgcgaa ccgccgggag aaggtacgcg gcgacaccgc ggcgtgccgg gccagcgcct
     1081 cgaggctcag cggctcaccg agccggtgca gcgcccactc ccgggtcgcg gcgaaccgct
     1141 cgcccagcgg ctccggcaca ctgcgcggca cgtactgcgc ctgacctcca ctgcggtagg
     1201 gggccgcgac cagccgccgg gccgcgtggt tggaggcggc cactcccagc tcgccgcgca
     1261 gcatgtgcag acacaggtcg atgccggagg ccgccccggc cgacgtgagc acgctgccct
     1321 cgtccacgaa cagcacgttc tcgtccaccc ggatcagggg atgcctggcc gccagggcgc
     1381 gcgcgtagtg ccagtgcgtg gtggcccgtc tgccgtccag cagaccggtg gccgccagcg
     1441 cgaacgcccc cgtcgagatc gccgccagcc gagcaccccg tccgtgcgcc gcgaccagcg
     1501 ccgccaccac cggctccggc ggctcctccc ggtccgggaa ccggtagccc ggcacgaaca
     1561 ccacgtccgc ccactccagc gcctccaggc cgtgcgccac gtggtacgac aggccgtcgc
     1621 cgcccgtcac cagacccggc gcggccccgc acacccgcac ctcgtagggc atgctcgcgc
     1681 gggtcgtgaa cacctgcgcc gggataccca cgtcgagcgg cttggcgccc tccaggacga
     1741 ggacggcgac acggcggaaa cgggaggacg gcacgggcag cagggtacgc acaggtcggc
     1801 gtgaatcccc cgcagggcac cgggcaaccc cccgatatgc tgctgttttc tccagtaccg
     1861 gccgcctcgg aaggaatgcc ccgtggagtt ccggctgctc ggcaccgtct ccgtcgacac
     1921 ccgccgggga ccgctgccgc tcggccccgc caagcgccgc agcctgctcg cggcgctgct
     1981 gctgtcggcc aacaccccgg tgccgatggg ccggctgacg gcgtgcctgt gggacgacga
     2041 gccgccgagc caggcgcgcg gagtcatcca gggccatgtg tcccggctgc gcgccctgct
     2101 caccgagggc gacgcggagg cgtacggcgt cgaactcctc accgccgggg acgcgtacgc
     2161 gctgcggctg ccggaaaccc tgctcgacgc ccagcggttc gaggagctgc tcaccctcgc
     2221 ccgcgaacag cgcgaccccg ccgacgcggt gctcatgctc ggcgacgccc tcgcgctgtg
     2281 gcgcggaccc gcgctcggcg gcgccttcgc cggaccgccg ctccaggccg ccgcgcactc
     2341 gctggaggag tcccggctct ccgccgtgga acaactggcg ctcgcctacg gcaggctggg
     2401 cgagcatcac cgggccgccg ccgtcctgcg caccgaggcc gtcgcgcatc cgctgcgcga
     2461 atcgctgtcc gccgcgctga tgaccgccct gtaccaggcg ggtcggcagt cggaggcgct
     2521 cgactggttc caccgcaccc gcaggcttct cgcggacgaa ctcggcatcg accccggccg
     2581 cgaactcgcc gacgcctacg ggctgatcct gcgcggcgac cccgtacccg agctgctggc
     2641 cgcgcgtccc aagcccacgc ccaagcccga ggccgacccc gtccggccgc ccgtaccgcc
     2701 ccgccccgct ctcgtgcccg ccgaggcgca cgccgacctg ctgccccgcg cgccccgcgg
     2761 cttccacggc cggggcgcgg aactcgccgc gctcggccgg gccgccgccg gggaggcgcc
     2821 ggtgtgcctg gtgaccgggc ccgccggcgt cggcaagacc gccctcgcgc tgtggtgggc
     2881 gcaccgcaac gccgacgcct tccccgacgg gcggctcttc gccgacctgc acggcttcag
     2941 cgacaccggc gagccctcgg tgaccgaggt gctgcgcgag ttcctgctcg ccctcggggt
     3001 gccgccgcgc cggataccgg aatcggcccc ggccgccgcc gcgctgttcc gcaccctcac
     3061 cgaccggctg cggctgctgg tcgtcctcga caacgcgcgt gactccgcca ccgtccgcac
     3121 cctgctgccc ggcggcgccg actgcgtcac cgtcgtcacc agccgccacc gcctggaggg
     3181 gctcatcgcc tccgacgcgg cccggcccgt ccccgtcggc acgctggacg cgcaggacgg
     3241 tacggcactg ctcgcgggcg tcctcgggga ggaacgggtg ctcggggagc cggtggccgc
     3301 gcgcagactc gccgaactct gcggagggct cccgctggcc ctcagggtca cggcggcccg
     3361 gctcgcgggc cgcccgcagt ggagcctcgc ccacctcgcg gacgaactgg cggacgagcg
     3421 cggccggctg gcccacctcg ccgtggacga caccggggtc ccggccgccc tccgcctgac
     3481 cgtgcagcac cttcccggcg aggccgcgca ccacttcggc cggctcggcc accaccccgg
     3541 tacccacttc gacccctaca ccgcggccgc cctcgccggc accgacccgc cggccgccgc
     3601 ccgcgccctc gaacgcctgg gcgccgccca cctcgtcacc gagaccgcgc cgggccgctg
     3661 ggagctgcac gacctcgtac gtctctacgc ccgcgacctc gaccccgcga ccgggcccac
     3721 ggcgctcacg ggcgccctgg accactacat cgccaccgcc ctcgccgccg cggagacggc
     3781 ccagccgggc ggcgagccct gtttcgcact gcccgaggac ttccggcgcc cctctgccgt
     3841 acgggacttc gccgatcgcg cggaggccat ggactggctg gccgccgagc gggaggacct
     3901 ggcacgggcg gtgaccgccg cgcgggccgc cgggctggac gaccgtgcct ggcggatcat
     3961 cctcctgcag tggccccagg tggtctggcg ctcgcgggac aactgggtgc cgctgctgta
     4021 cacggccctg gagtgcgccc aggccgtgga cgacccgtac gccgagtccc gggtccgcac
     4081 cctgctcggc tgggtcctga gcgaggaggg ccgcctcgtg gacgccctca ccctcctcga
     4141 accctcaccc gccctggccc gtcggaccgc cgaccgcctg ggcgaggcca ccgccctcgt
     4201 caacctggcc gtggtccagt ccgcccaggg cgacctcaac gcggccctgg ccaactgcgc
     4261 ccgagccgcc accctggccc gcgaggaggg caacccccac acggagatgc tcgccctgct
     4321 ccacctctcc cgcacccacc tctcctcggg cgacccggac cgcgccctcc acgtcgcccg
     4381 aacggccctg gacctcggcc ccgaacacga ggaagccgcc cgcacctccc tcctccacac
     4441 cgtctccggc gaggcgcatc tggccctcgg caacaagacc gaggccctcc acctcctgga
     4501 acgcgccgcc gacgaggcgg agtccacggg ctacgacgaa ggcgcggtac gcgccctgga
     4561 ggccctgctc cgggtgagcg gccgcgcgga ccaccgcaag cgccacgagg aggcggtacg
     4621 gaggctggcg ggggaggacc ggtaggactg gctgtcgcta cggtggcccc atgtgccgct
     4681 acgccgtgac cccctacaag ctccactacg cgtgcctccc gtgccgggtc agcttcaagc
     4741 ggcacgcgga tcgggagcac gcgtgcccga actgcgcccg gccgctcgtg tgtgccgggc
     4801 gggacttcgc tccgccgcgt cggcgggatg tcgcggggtg gtcggtggtc gccgcggtgc
     4861 tgggggaggg gctgcgcttc gacgggcggt cggggtgtgg gtgcgcgaag gagccgaagt
     4921 accggccccg gacgcgggcg gagctgcggg tgcggcggat cgtcgccctg cgggaggggg
     4981 tgccgccggc cgaggtgctg gggcgggtcg atccgctgga cggcggcggc cccggcccgg
     5041 cgtcagaagg acgttagccg gacgtcagcg ggacggcagc gggggcggtg agagtagggg
     5101 tgtcagcagg tcagtggctg gccggcggtt cggaagggcc gtcgtcgacg tttcacctct
     5161 cgggggaaaa tcatcatgaa cgcctcgcgc cgtacggcac tcttctccgt cgccgcttcc
     5221 gccgcgctcg ccctgtccct gaccgcctgc cagagcggcg aggggaccaa ggccgaggga
     5281 gcggcgccgg tcgccgggga cacggtctcc gcctccgcct ccgccgctgc ctccgcgccc
     5341 gccgccggtg cgggcaccgg cggcgacacc ggctcgggca ccggcaccgc cgtggggacc
     5401 gcgcacaagt ccggcgccac gtcctccggg gccaagaagg gcaccgccac ccccctctgc
     5461 cgggcccagg acgtcaaggt cagctccgag cgtcaggacg ggccgcccta cacccacatc
     5521 atcctgaccg cgcggaacac ctcgggccac cgttgcgaga tggccgggtt cccgcacatc
     5581 cagttcctgg agagccacaa gcaggacgtg ccgtccgtgg cgaagagcaa gccggccgtc
     5641 ccgaccgtgc tgaaccccgg tgacccggcg ttcgtcctgg tcaagctgtc cgacggcggg
     5701 gtggacgagg acaacgaggt ggtgaacgcg ttccagttgg tgcttgaggg cgactccgcc
     5761 gtcatcgcgg tggactcctc ggccggcggc ggcctcgccg tcgaccccgc gaagacgctc
     5821 accgggtact ggacgaccga actgcgcaac ggggccgacg acttctgacc cgtaccgccg
     5881 tgagaccgcc ccctcgggag aggaagatca cccgtggggg cgcggtcttg gccaggcagg
     5941 gcgcacgcgg taccgtcggg gcgatatcga cgacggcgaa acggaagccg gtgagaaacc
     6001 ggcacggtcg cgccactgtg tgcgtggtcc cgcgaggggc cgcgcgagtc agacccgtgg
     6061 ccgtcgtcct gtgcaccacc gagatgggac gcgaactccc agaggaggta ctgccatggc
     6121 gcagaccgtc gctcagccga ccgccggaaa ccccgccgct cccgccaccc tgccgctgaa
     6181 ggagatagcg ccctgggcgg tcttcttcgg cgtcctcatg ctggtcctgc tgtacttcgt
     6241 cggcgccgag cagggcgcca cctccgtgtt caacggcacg gacgtccacg agtgggtgca
     6301 cgacgcccgt cacctgctcg gcttcccctg ccactgacgc gagggacgcc gcacacccat
     6361 gaactccgca accgtgagaa acctcctcgt gcggggcatg ctcgccggcc tcggcgccgg
     6421 agtgctcgcc ctcgtcgccg cgtacttcct cggcgagccc aacgtggaca gcgccatcag
     6481 cttcgagggc caccacgccc acgagcacga ggtcgaagtc gtctcccgct cgctccagtc
     6541 caccgccgga ctggccaccg gcgtcctcgt ctacggggtc gccttcggcg gcatcgccgc
     6601 gctcgcctac tgcttcgcgc tcggccgcgt cggccgcttc ggcccccgcg cgagcgccct
     6661 gctgctctcc ggcaccgcgc tgctcgccgt gtacgtcgtg ccgttcctga agtacccggc
     6721 caacccgccc tcggtcggcg acccggacac catcggcaag cggaccacgc tgtacttcct
     6781 gatgatgctg ctcagcgtgc tcctggcgat cggcgccacc ctgctcggca aacgcctcgc
     6841 cccccgcctg ggcaactggt acgcgaccct ggtcgcggtg gccgccttcg ccctgctgac
     6901 cggtctggcg tacgccttcc tgcccgtcgt caacgaggtg ccggaacact tcccggccac
     6961 cctgctgtgg cggttccgtc tctccgcgct ggccatccag acggtgctct gggccggatt
     7021 cggtctgctc ttcggcgagt tggccgagcg gctgctgaat ccgcgccccg cggcggcacg
     7081 cggcacgggc caggcggtcg ccgcctccca ctgagccggt gacctgacgc cgaaaggggc
     7141 cccggagatc tccggggccc ctctcaccca cccccgaccg cgtgccccag ccgcaggttc
     7201 cagcgtccgg cccgcccgga cagttccgtc gcggtgagcg gtgccacgtc cagccgccag
     7261 aaggctccgg tgggcagccc cagcgcgtgg accacggccg cgcgcaccac ctcgggttcc
     7321 acgacggcga ccgtgcggcc ctcgggcacc gactccagcc agcgccccac ccgtgcgcac
     7381 acctggcgca ccgactcgcc gcccggtgcc ggatactccg ggtctctcag ccaccgggcc
     7441 agcgcctccc cctccgccgc gccgacctcg gccagcgcgc gcccgcgcca ccgcccggcg
     7501 tccagcggcg cgagctccgc cgccaccgcg ccccgcagcc ccagcgcctc ggccgtgtcc
     7561 cggcaccgcg caccgggcga caccatcacc cgcgccgcct ccggcaacgc cttggccgcc
     7621 gcccgcgccc gagcggctcc cccctggtcg acggacgagg aaccgtcgta gaaccgggcc
     7681 tcacgcagcg cgggcccgat ggcgggcgac acgagcacca gccgactgct cacccgggaa
     7741 acctcctgat cacaagggtc cgtcccgtct cgcggccggg ccggagggtg ggacgaacgg
     7801 tcgctcgaac taacgcagtt caccccgcac ggtacgggcc gccgccacca ggttccccag
     7861 cgacgcccgc gtctccggcc aggcgcgggt cttcaggcca cagtccgggt tcacccacag
     7921 tcgctcggcc gggatcgcct tcagccccgt ccgcagcagc tcggccgcct cctccgcgct
     7981 cggcacgccc ggggagtgga tgtcgtacac gcccggaccc ccctcgcggg ggtagccgtg
     8041 cacggccagt tcgcgggcca cccgcatgtg ggagcgggcg gcctccaggc cgacaccccg
     8101 cctggcggac ggggcgaacc agctgcgggg ctcagcctac gggccgtgac cgcgcgccgc
     8161 cggtgccgtc cggcatccgg agggtgatcc gggccacgcc cgtcacgcgg ccgccgggtc
     8221 cagctgggcc agcgcggccg tgaccagggc cgccgtgccg gtgcccaggg tgaggcggac
     8281 gctggggagg tagcgggggg agtggttgtg ggggaggccg cggaacttct cggcgggccc
     8341 gtcgccggga gcggccgccc actgggtggg gccgaccgag ccgagcatcc agtaggcgcc
     8401 ccggatgccg gggcgcccgt gcagatggcc gcccgcgccg gtgagcagcg ggaagtcctc
     8461 cgtcgccgac gacgcgggcc agccggtgac gcgggcggcg ccgaaggccg cctggtgggc
     8521 ggcgcgtacg gccgcggtga caccggggtc gggccgggtg accccggagc gggccagctc
     8581 gcgcacggtg acccgcggcg ccgtcgcggc cgaggccgcc tccgcgcgca ccacccgctc
     8641 caccgccgcc gcgccccgca ccagcgccgc ctccgacagg gcgcggacgg tgacccgcag
     8701 ctcggcgcgg gtggctatga cgttcccggt gcgcccggtg tccccggcgc gcagcgagga
     8761 cgcggtgacc agcagccgtt cggccgggtc cgtctcgcgg gcggcgacgg ccgggaaccg
     8821 ggtcaccgcc ccggccgccg ccagcagcgg atcggccgtc agatgcgggg tggccgcgtg
     8881 ccctccgtcg ccctcgaaga ccacctccag cgtcacgctg cccgccatca gcggcccgtc
     8941 ggcgtgcgcc accatcccgg ccgggaacgc tgcggtgtgc tgggcgagga ccacgtccgg
     9001 cgcggtgatc cggtcgtaca gaccgtcctc cagcatggcg cgggcaccgc tcagcgtctc
     9061 ctcggcgggc tgcccgacga ccagcagggt gccacgccag cggtcccggt gctccgcgag
     9121 ccagcgggcc gcggccgccg cgcacgccag gtgggcgtcg tgcccgcagg cgtgcatcac
     9181 cggcaccggc cgcccgtccg ggcccggtgc ggtcgcggtg ctggcgtacg gcacgccggt
     9241 ctcctcggcc accggcagcg cgtccagctc ggcacgcagc agcacggccg ggccgtcgcc
     9301 gttgggcagt tcggcggcga ccccgtggcc gccgaccccg cgcagcacgc ggaagccgtc
     9361 ggtcgtgagc cggtccgcga accgggcggc ggtgcgctcc tcggcgccgg acagctcggg
     9421 gtgccggtgc aggtcgagat acagctcggc ggtggacggc agcagggcgt ccagaccggg
     9481 cggcgcacca ccggccgcgg tcacggacgg acgggactgg tcgctgctca cagcgggggc
     9541 tccaagggtt cggcgtacgg gggtgtcagc gaagtgacag ccatcggtca gggagttggt
     9601 gccggacgcg cgtagaaagg agatgtcggg gggcgcgctc ctccggctgg ttcagcgcac
     9661 caccggacgg ggcggtcccg gccggccgca gctcacctga cccggaagga gccaccatgg
     9721 ctgacaacac cctcgcctcc ctcgcccagg agatcctgga cctggagtcg gagaccttcg
     9781 agatcaccga ctactcggac gccagcgagg tcatgctcgg ttcgtccacg agctgttcct
     9841 ccaccagcac ctgctccagc accaccagca ccacctcctg caccgcctga cgcaggcgtt
     9901 cgcacccacg gtccccggtc cgcctcggcg cgccggggac cgccggtgtg cgcgggcccc
     9961 ttcacggccc gcgcgccgac gagcggaacg cctgccccgc tcacgggaac ggatgcggca
    10021 cccgccgcaa ctcctcctcc ccgagcggcg ccgggaccat gcccgcccgg tacggcgcgg
    10081 tacgcagcct cggcagggtc agggcccgct gccgcagcca cccgaagtcg atcggcagca
    10141 gccccggagc cagcgtggcc accgtgcgca gccccatccg gcgctgctcg ggcgtggtct
    10201 ggtcgacggc gatcacctcg cagcccgcct cgcccaacag gtcccgcacc agcagcagat
    10261 cgtcgcggag gtccccggtg cgcggccgcc gctcctccca cccggcgaac agctcgtcca
    10321 gcggagccgt gcggggcggc ttcagatagc cggtggcgtg gacgcgcatc gcgggcagtc
    10381 cgaacagcgc cgcgtggtcc ggaagacgct tcaccaggtc gaagtcctcc gccatggcgg
    10441 cgagttcggt gggccgctcg gccacctggc cgggcaggtg cgggatgtag gtgaggatct
    10501 cggagaccgc ggactccacc gccgtctccg ggtcgaagga ggcgcccgcc gcgaaggcca
    10561 gggaacccgg cgcgtcgtcg cggcggaccg cgagccccgt gacgacgggc accgggaggt
    10621 ccacccggtt gtcgaagacg tgcacgtcgt agccctggag cgcggcccgt gccaccatcg
    10681 cccgcacgcc cggcgagcgc accgagtcca ggtcgatctc ggggagcggg agatcgccgt
    10741 accagccgag caggaaggcg tcccgctcga tcagttcgag caggccgaag aagaccgctt
    10801 cctcccaact gctgccggtg gcgcagccgt tggagcactc gaagacgaag ttgtcggcgg
    10861 ccgtgcccgc gctgtagtag acgaggcggg ccgggaccag caccgggcgg ccgtcccgca
    10921 gcgaccagcc ggtgacccac gggatcggcc gggccgggtc gaagggctcg accatggggt
    10981 cctcggcgta ggtgcgcggc ccgtacagcc cgcaggcgcg cggatcgagg gcgcggtcgc
    11041 ccagttcctc cagcgacgcc gtcaccaccg gcgcgcggtg ccggcggtgg gtgcccgcgt
    11101 accgctccag gccctccagg aaggccaggt cgcggctgtc cgcgaaggag ttggcctggc
    11161 cgctccaggt gacgtcggtg agaccggcgt acccccgcat gaagacgctg cccgcgaccg
    11221 gcgcggtggt gggggaggtg acgtcgatcc aggtgccgcc gccgagcacc ccgcacaccg
    11281 ggttggccag cgccttcacc ggcagcgggt ggtccgacgc ccggcgcagc cggtacgagt
    11341 ccgggcgcgg cttgggcagc ggggccgggg cgggcagggt ggcctccgcg gccgcgcgcg
    11401 aggccgcctc ctcggtgaag ggacggcagc gcgggcacgt cggctccggc agcagcggga
    11461 acgtccgtac ccggagcgtc tccaggtcca cctccgtgac ccggggcagc tcggcgtccg
    11521 ggccctcggc ggtgtgccgg gcggcgccgg aggcgatcag ccggtgcagc gaccacaccg
    11581 cgtccaccgt gtggtccggc agtaccggcc aggccccggc cgccgtcgtc cccgtaccgg
    11641 tctccagcgc ctcccgctcg gtgcgggtgc gcagccgctg gcggcgcatc gccagacagg
    11701 tcccgcaggc cgggccggcc gccggggtgc cgccccaggg gccgagcagc acggcctgcg
    11761 cggtcaggtg cacggtggcc ggttcggcgg ggagcccgct cccgccctcg ccgagcacgt
    11821 tggtgtcgcc gatccgggag acggcgggcg tgtgcagccc ggcggcggtg gcacgcgccg
    11881 ccagccggga gtggaggtcg gcccgcgcgg cctccagtgg cgtcgtcgtg gtcgtcatgt
    11941 ccggttgctc cagcggaaga tccgggtggc gacgaccccg aagaccaggg cgaacacggc
    12001 gaggcccgcg cagtccagcg cgatgtcccc caggtcgccc cggccgccca tcgcgtcggt
    12061 gagaccgtcg ttgagatagt gcagcggcag taccttggcg gcggtgcgca gccagctcgg
    12121 catcaggtcg tccgggaaga acgagccgga caggaacgcc atcggcacca tcaccaggtt
    12181 ggcgatggcc gcgaccgcct ccggggtgtc cgccaggctg ccgaccacca gccccatggc
    12241 gaggaacgcg gtcaccccca gcaccagcag cggcagcgcc gcccaccagg ggcccatcag
    12301 cctcagcccg aagaacggca gcagcgcgac ggcggtgaag agcacggtct gcgtcagcgc
    12361 cacgcccatc gccaccgtcc agcgcgaggc cagcagggtg cgcagcgggg tcggggtgcg
    12421 ccagatcagc cggagcaggt cgtcccggcg ccactgcatc agcgcgaacc ccaccgagaa
    12481 cacggccgcg ttgcccacgc cccaggacag cacgcccggc gcgatgtagt tgatggaggc
    12541 cagtccgccg tcgaccttgt cgccctggaa gatcaggccg aacagcacca ggaaggcgag
    12601 cgggaaggcg aaggtgaaga agagggtggt cttgtcgcgc acgctcgcga cataggtggc
    12661 cctggtcagt gcggcgtagg cgctcaacgg tggtgctccg atccggtgcc ggtcagtgag
    12721 aggtaggcgt cttcgagggt gggggtgcgc accgacaccg cgtcgatgtc caccaggtcg
    12781 ccgagtgcgg ggagcacccg gttgggtacc gccgtctcga tgaccaggtc ggcgccccgc
    12841 acggtggccc ggtccacgcc cgccagtgcg agcgccgcct tgggggacac cttgtcggcg
    12901 ggcaccagca ggcgggtcgg cgcggccagg gcgcggatca ggctgcgggg cgagtccagc
    12961 gcgacgaccc ggcctccggc gatgatcgcc acccggtcgc acagcgcctc ggcctcgtcc
    13021 aggtagtggg tggtgcagat gatcgtccgc ccctccgagc gcaacgaccg cagcagctcc
    13081 cacagttcgc ggcgagcctc ggggtcgagg gcggccgtcg gctcgtccag gaagatcagc
    13141 tccggctcgt tgagcagcgc ggtggccacc gcgagccgct gccgctggcc gccggagaga
    13201 tggtcgatcc gggcgtccgc cttctcggtc aggccgaccc gctccagcgc ggtcctcgcg
    13261 gcctccggcg ccatgccgta cagcgcggcc accgtgcgca ggtgctcggc ggccgtcagc
    13321 cgggcgaaga acgcagacgc ctgggtctgc acgccgatcc gggccagcag cgcgatgtcg
    13381 cgcggccagg gactctgccc gaagacggtg acggtgccgg agtcggcctc ccgcatgccc
    13441 tccacgatct ccaccagggt ggtcttcccc gcgccgttcg gcccgaggat gccgaagaac
    13501 tcaccgtggc gcacctccag ggagacgccg tccagcgccg tcacctcccc gtagcgcttg
    13561 ctgacgccgt ccagggcgac gacggtctcg gtggtggtgc cgcgcggggc ggcctccgtc
    13621 ctgctctcgg gtgcgctcat ctcgcctttc ctcaactgtg ctaccgcgga ggcgacgtgc
    13681 cgccccggtt cggacgtggg ggaggcggcc gggaccgccc cggtggtacg acggtcccgc
    13741 aggcgccggc cgaggccgcc cagcacccac agcagcagga cggcggcgag cagcgcgggc
    13801 ggcagcgacc aggcgagcac cgccgcgccg tcgggcagca tcgctcgcag cgccgccccg
    13861 cacagcacca gcagcgccgc gctctgcacc gccgtcagca gcgcgaaccc gccgtacagc
    13921 agccgcaggc gcgccgggta cgcggcgagg ccgggaccgc gccggaacag cgcccgcacc
    13981 gcgaggccgg tgaaggtacg ggcgccctcg gacaggccgg tgacgccgag cgcgtggccg
    14041 agcgccttgt agccgtccag cggaggcagc gggaggaggt tggccacgcc gaggacggtg
    14101 ccgagcagca gcagcgcgcc caacgcgggc cgggcctcgg cgccggccgg gagcagcgcc
    14161 cacaccgcgt agaacggcac caggaacagg aggttggcga agacgcccgc gcacgccgtg
    14221 gccaccttcc ggcgccggcc gccgaggaac tggacgtcct ccacctcgca gtacagatag
    14281 ctggcgaagc agatccagcg cagcccgatc tccgtgaccc gcccgcccca ggcccgcgcg
    14341 aacagcccgt gcgccagttc gtgcagggcc agtccgcacc agagcacaca gccgatcgcg
    14401 aacagcagca ccggctggcg cgccgtctcc tccgtctgcc gccacagcgt cccggcccgc
    14461 accacgacgg cgacgagcac accggtcgcc agtgccgtca gcaccgcgag gacggccggc
    14521 cggcgcgccg gcgcggtgag ccggtgcagc cggtccatca gcgcgggcgc gtcggccacc
    14581 atccgggtcc gcccggccag aatgccgttc ggcggccgct cgggcccggc cggcggtgcc
    14641 gcggccgggg cgggggagcc ctccagcagg ccccggccgt gcagcagccg gagcaactgc
    14701 ccccactgcg cctccccgag ccgggcaccg aacgcgcccg cgtactcccc gccgatctcc
    14761 tccagggtgc gggagccgtc cagccgggtg atcaggaagt gctccttcgg ccccagctcc
    14821 agccgccgcc ccgtacgcgg gtccttcagc agatggatgc gggccgtccc gcgcaccagc
    14881 cggggcccct cgaccaggtc ggggcgcatc cgggggcgac tggcgaggaa cgtcccggtg
    14941 gtcacccctc acccccgggg cgccagcccg cgagcgagtc acccgcgccg gccccggcgc
    15001 cccgcgcgcc gccgtccctg agggcgcggg cgagcacgta cgacaggaac gcctcgtcgc
    15061 gcacggtcgt gctgagccgg ttgttggtca tgtgcaggta cggcgagagc agcatcggca
    15121 gcgactgggc cgggtcggtg gggcgcaggt cgcgggtgcc gtcccaggag cggaagacca
    15181 gctcgccgtc ccgggtcagc gcggtcgccc ggtcgcgcag ctcggcgcag tgcccggccc
    15241 agccgcgcag gaacgccggg agccgcccgg tcccgcccgc cgcgaccgcc gcccggatgt
    15301 cccggaaccg gcccggcagg ctcgtgccca tggcggagta ggcgcggtcg tagccgtcgt
    15361 cggcggtgta gttggtggtg gagaacgccc ggttccagaa ggtgtggtag cggtccagga
    15421 aggacagcag ggcctcgtcg tcccgcagga aggtgccggc catcaccgtc atcaactggg
    15481 ccgacagccc gagcagtacg gtgcgcaggt ggaggttcat cgagcgggcg gcctcgatga
    15541 ccaggtcgct ggagtgctgg aagtgccact ccgccagctc ggtcccggcc ggaccgccgt
    15601 acttgccgta ctccggctcg tacgggcggt cctcgaagga gttgttgggg cgcagcacca
    15661 tccggccgtc cgggcccagg tacccggcgc gctcctcctc gccgaactcc agggcgaaca
    15721 gggtctcgta gaggtcggcg aagaagccgt ccttcacctc gtacagcgcg ggccgctcgc
    15781 gcaggaacgt ctccagcgcg gcgtgcgccc gctcccggac cacgggggcg tcggcggcgc
    15841 ggaccggttt caggcgcagg cgcaggtgcg ggccctccag ccagtagttg atgaagaagt
    15901 acccggcgag caggccctcc tcggtgaggg cgtcgaccag cgggcggacg cactggacga
    15961 gcagcgggcg ggggctggcc gcgtagaaga cgtgcacggc cagccactcg ccgggcgccc
    16021 ggccgggcag tgccgaggct tcggtgggag cggtcgtcat cgggtggcgt cctcttcggt
    16081 ccgggcggcc gctacgggca gcagttcgac ggcgagttcg gccacgtgcc gtccgcgcgg
    16141 tgaggtgacg tgcagctcgt cctcggcggg gagcatctcc tcgaagacgg tccgggcctg
    16201 tttcccggcg aggagtcctt ccagggcggt gagcgagagc gggctctcga agtcgacgta
    16261 ctgaggcttg gacccgccgg accaggccgc gccccggtcg ccccccgtct cctcgtggac
    16321 ggtggcgaag acacgggcgg gcaggccgtg ccggacccgc cagcggtgcc aggcgagata
    16381 ccagtcggcg tccgtggtgc cgggcgcccg cagcgggagg tggccgtcgg cgacggtcca
    16441 ggagcggcgc tggagcacca gcgcgtggtg gcggacacgg gggcgccggg tgacgccgtc
    16501 cgtcgcctcg ccggccggca ccccgcgcca cacgtccggc accgagcggg aggtgggcga
    16561 gaacagcagc agggtgcgcg ggatctcggg cagcaccatc ggcaccagat agccgaggta
    16621 caccgggacg acctcgcggt ccaggcgccg ggaacgcagc agcagccggt cctcggtctc
    16681 gtcgtgcacg gcgtacaggt cgtccagatg gaggcgggcc tgtccggggg cggtgctgtt
    16741 ctcgcccggg cagacgatct cgtagtcggt cagccggccg tgcaggttga ggttggtggt
    16801 cgcggcaccg gccgtcacct ccgcgaggac cgcaccgggc ggcagcaccg aacgcaggcc
    16861 gtcgcgcagc gtgtcggtga gcccaggtcc ccccgcgccg tcgaagcagt gcgtgaagcg
    16921 ggtgaagggg aagcagaggc cgccgtagga gttgttcagc acggccagcg ggccgtccgc
    16981 gcgacgggcg agctggacga agtggctctg cgggcggaac gcgggcgcgg ccgtgccgag
    17041 cgcctcggcc atctcgtcca cggtcgcgtc gtcgagcacg aactccaccg catccggcgg
    17101 tagttcggcc cagcgcttgc gcatccgggc cgtcagcgtg gcgcgggcac ggtcgatgga
    17161 ggtgatctcc gggacgccga gccagttctc ctccggggcg tggctgccgt ccgggaggtg
    17221 gccgtccttg gccgcggtga actggaggta ctggcggaag atgtcctcgt ggaagtcgtg
    17281 caccagccgc agcaggtcct cgcagcggcc gccgcgcccg taccgggcga cgaagaagcc
    17341 cttgagggtg agccgctggg gcagcgccac gtcgaaggcg ggcagcaccc ggccgatcga
    17401 ccgcagcggc gcggcgaccg gctcggccca ctcggcgagc ggcgcgccgg tggtgccggc
    17461 cgacacgtcc tcgtagagca aggtccgcgg caggacggct cgttcggcac ccagctcggc
    17521 ctggagagcg gtgaggtcgg tacggagtcc ggccagcagg gcgcgccggg tgggcacatc
    17581 ggcgtccccg taccgcgcga ccgcctcggc cgggccgtcc agccgggcgg cgacggtgtc
    17641 cgcccactcc actcccaggc tccgcaaggc ccgctggaag gcgcgcagcg ggtcggggct
    17701 gtgcacgccg gtgtcgagca acggaagctg gagcatgccc agttcacgca gcgccgtcag
    17761 atagtgccct gcctcctcct cgccggcacc cgtggtggcg cccagccagc gggccaggtc
    17821 gccgtgggtc agggtgccgc cggtgtcgcg cagcagcgtc agcatcccgt cgagggcgcc
    17881 ctgccggcgc aggaagaaca gccggtcctg ggcggcgtcg aaactgaccg gcgcgctgtc
    17941 gtccccggcc gtcaccgccc gccggacaaa gcgcacccgg tcgtcgtccc gcgtccagcc
    18001 cgaggccggt gccaccggca ggtcggcccg gcgggccggg tcggccacga tcagctcggc
    18061 gagccgggtg aggacgacca cgttgagccg ggggtggctc gtccagccgt cacccacctc
    18121 cgtcaggtcg ccgccctccc cgaaaccgcc cagcgccacc ccggtcagcg tgctgaaggg
    18181 gctggtcttg caggcggtcc ggtacaggta cgacagcagc gagcgctcca tcttccgggc
    18241 ccgcttgccc ggcgccgggg accggtcggc ggcgaacgcg tcgagccgct cctccagcgt
    18301 gggcgaggcc agcagcagac cccggcgcag ccggtcgtcc agcgccagcc cgcgcagcgc
    18361 ggcacgggtg cgggcgagcg cgccaccgag cacggtctcg ccctcggcgc gcagttcctc
    18421 ccagcgccgg cgtgcgttaa gccaggcggt gaggtccgcg ccggtgccac cgcccagccc
    18481 cgaggccagg gcgcgggcgg cggggaggtc ggcggggagg cggttgttga agacctggcg
    18541 gcgcagcgcg agcaggcggc ggcgcagggc cgcgtcctcg gtggcgccga cggcggcgga
    18601 gagcgggtcg ctcagccggg cccccagcgc gcgcagcctg tcctcctcgg cggccgcgcg
    18661 ggcggcccag tcggcggtct cgggggcgcg cagcgccgag acggtctcgg ccgggaggcc
    18721 ggccacgcgc agcatgaaac ggcggtgcag ggtcacagtg gtgtcggcgg ctgtggtggc
    18781 cgggctcata ccgtgctgcc cctctcgtgt cgggactccc gcggaccggg caggaggcgg
    18841 tcggtcgggc gggtcatggg gcgacgatgt cgtagcggta atcggcgggc cggggccgtt
    18901 cctcgccgat catcatgatc agcagcggca cctctccccg gccggccacc ccgaactcct
    18961 ccgcgtacga cacgcagtcg aagccgagcg ccaccccgca gccggtcccg gcggcggagg
    19021 cggcggtgta gacggcctgg gcgatggcgc ccacggcggc gttgaccagc cgcagccccc
    19081 ggtcgcccac ggcgtccagc accgcgtacg tccgggccac cggtaccagc acggcggccg
    19141 cctgctccag gttgtagttg gcgaggaagt agttctcctg gaggaacgcc ccgaacccgc
    19201 ccggcttcag cagcaccagg ccgccggtgt cccggtcgta ctcgtacagc cccggcggta
    19261 cgtcacgtac gtggttgacg aagacgtgga accgggtcag cggcggggcg cccggggtct
    19321 ccacgtcgct gtccagggtg gcggccgtga cggcggcggc cagtgtcacc gacagcttcg
    19381 ccgggtccag cggctccccc gcgctgaacc ggccgaagct gctgcgccgc tcccgcagcg
    19441 cccgtcgcac ggtggtgtcc agcggcgccg ggtccggcag cggcacccgc tcgccgtccc
    19501 ccgccgcagc cgcgagcgcc gggtccagcc ggccgggggc gggccggtcg gcggcaccct
    19561 ccagcgtggc ctcgtgcacc cgggccagcg tggggaaggc cagcgtccgg cgcgaacgct
    19621 cgtccggcac ccgccgcacc gccgctcccg gcgtctcggg ggcggccgct tccggcgcgg
    19681 gcgcgtccca gcgcagcggc accacggcga acaccccgtc ctcggcgggg tccagcccca
    19741 gcaggcgccc gacgcgcggt tcgtcgaacc acagggcggt gtccagccgc agcccgtgcg
    19801 cccgcgccca catccgccag gtctccagca gggcgccgat gtccatcgtc acggcgtggt
    19861 aggagaagct gttgtacttg aaggcgttct gccagaaggt cacgcccagc accaggaact
    19921 ggtcggtgtc ggcctccgcc aagtcgccca gcgctgaccg gacttcaccg gtcacgtcac
    19981 cggacagcag ccggttcagc cggtggtgcg gggtgtcgta gtagtagacg cccggtgtga
    20041 gcgggccgct cgcgccgctc acccagtgca cgccgatcgg gtacaggccg ccgcccgagg
    20101 cggtgccgcg cgaccagttg gcgtgggtgt ggaacggcag cgaacccagg tccgtgttgg
    20161 cctgcacggc cagccggcgt ccggtcaacc cgtaggagtc ccggagcatc gcacccagca
    20221 ggggcagcgt gaacgcgccg gtgcccggct cgccgaacag gccccggccc agcgtggcgt
    20281 cgtccgcgca gccgccgtcg ggcagcggga aggagggcac gccggggaag tacttgccct
    20341 tgcggggccg gtcggcccag tccggcacga agtcggccgg ctccatgggg gtcctgcccc
    20401 gccgcatcac cgcggtcgcg tactcatggg cgtatcccat ggtcactccc tagtcagctc
    20461 gtctgtggcg ggcgcccggc ggttcgggcc gggcgcccgg gatgtcgttg gtgcggacag
    20521 ccgcgggggc ggtcagggga aggggtgggg cgccggattg cattcgtccg gcggcagatc
    20581 cgccgtacgc agcccggcct cccgcagcgc tgtgcgggta cggggcagcc acgggccgcg
    20641 ctggcggctc cacccgaagt cgatcgggag gagaccgggc accagcacct tggccgtgct
    20701 gagccccaac ccccgctgct ccggggcggt ctggtcgacc accaccacgt cgaaaccgcg
    20761 tgcggtcacc tccgccacga ccgcctccac gtccgcgcgc agatccgccg ggcgggaccg
    20821 ggggcggtcg ggggcgagcg aggcgagcgg gacgcggtca ccgtcgtccc ggccgcgcag
    20881 caggaagtcg gtgtaccggc ccatctccgg cagcccgtac agcagcggat gatcgtgcag
    20941 tacccgcacc tcgtcgaagt cggccgccat ccggcgcagc cgccgctcct cgcgggcggt
    21001 acggcggcgc aggttgaccg cgtcggtggc gatctcgcac agcccgcccg cgagcgcgtc
    21061 ctccgggtcg ggcgaggcgc ccgcgccgaa gcacagcagc cccggcccgc cgtccacccg
    21121 ctcggccacc gcggtcacca ccggcacggg gaagctgacc cgggtgtcga agaaccgcgc
    21181 ccggtacccg tacatcgcca gccggtccac catcgcgcgg gtcgccggcc gggtactgct
    21241 cgcggggtcg atctcgggca gcctggcccg gccgaaccag gccagcagga aggcgtcgcg
    21301 ctcgatggtc tccatcagcc cgtgatgcac ggcctcggcc ggacttccgc ccgaggcaca
    21361 gccgttggag ctctcctgca cgaaccggcg ccggataccg cccggcgcgt ggtagtaggc
    21421 caccacctcg gggacgagga ccggccggtc gtcccgcagc gaccagcccc acacccaccg
    21481 cacgggccgg tccggggcga accggggcgc gccgaccgcc tccgcgtcga aggtgtccgg
    21541 gtacagcccg ctgatccggg ggtcgaccgc cgtgtcgccc agctcctcca gcgtggccgt
    21601 gacgaccggg cgccgggcac gcgcccgcat ccccgcgtac cgctccagcc cctccagcag
    21661 cccgacccgc acactcgtgc cgtacgcccc ggtgtggccg ccccagtagc actcgcgcag
    21721 ataggcgccg gaacgggtgg tgaaggcgcc gaccgccgac gaggtggacg cggacgtcag
    21781 atcgggcgcc accaagggcc cgagcatccc ggtcaccggg ttggcgaacg cctccagcgg
    21841 gaggtcgtac gcggacaggg gccgggtacg gaagctgccc ggcgcgtgct ccggggcggg
    21901 ctccagggcg atccgggcgc cctcggccgt gtcgtccggc cggtccgcgc aggccgggca
    21961 ctcaccgtcc ggcaccagcg ggaacctggc gacccgcaac gtctccaggt ccagcagcca
    22021 cacccacgga tgccgcgggg cacgcgggtg cgcgtcggcc gccgagacca gcgcggccag
    22081 cgcgtccacc acgaagccgg cctcccacgg cggggttccg gtcgcgaggg tgggcccgcc
    22141 ctgctccagc gcgtcccgca ggaacccggc ccgcaccgcc tgccagcgcc gggccagaca
    22201 gcccggacac ccgcgcccgc ccacgggggc caccgggccg accacggcgt gatgcccgta
    22261 gagacccacc gggatcacgc cgggcgggaa ctccaccacg gcatcaccga gttggtcgcg
    22321 cacgcccagt gccctcaccg cggcggcccg gccggggacc cggcaggcga gcgccgaggt
    22381 cagctcttcg cacacgcggt cccagggcgc gtcgacggcg gccggcgccg cctccgtctc
    22441 agtgggcacc gggtccgcca cgggtgagca gcacgcgcac ggcgtggatc tcgcccgccg
    22501 ccaggtccgg cgcggccacc ggcaccgcga aggcgtcccg cccggccgcg gccagcgcgt
    22561 ccagcacctc ggcccagccc gtcccgtcgg cccgcaggga caccggctcg ccctcgggga
    22621 ccagcgccgc cgcctccagg tcggcccaca gcgggtcgcc gaggtccggc tcggcaccgg
    22681 cccgccgcat ctgctccgcc ccgagcagat cgcgcagcgc ctccagcacc gcctcgcgcg
    22741 gacgcagacc gctgcccggc gcccaccgca ccgccccgct ctccgggtcc gtgctgcggg
    22801 ccagggccac gggcagtgcg gtggcccccg ccccggtcag gtccagcacc tccaccgtga
    22861 cgcccaggtt ctccgccgag cgcagcagga acagcaactc ggcgtcagcg gtgagggagt
    22921 cgaggtccac cagtcgtgcg ggggccgccc tgcggaccac ccggcgcagg gcgtcgtggg
    22981 cgagggcgga gcgcagggcg cgggcgaggg cggcgcgggg ggtgcccgcc gcgcccgtac
    23041 ccgccgagga gcgctcgaac aggccctggt cgttccagcc actcagggtg cgcaccgcgc
    23101 cggtgggcac cagcacggta cgcccgtcca gcagcgaggt cgcctccgac caggcggaga
    23161 cccggtccac cggcacctga agcccactgg acagggcgag ttcggccggc gcgatccggc
    23221 tcccctcgcc gcccacccga ggcggcacca cctgctcggc gtacacctcc gcgccccgga
    23281 acagcgcggc gagccgggcc ccggccacat ggtgcacgtc gatcgcggag acctcgcgca
    23341 cccggccggg agagacgccc aggcgtacgg tgctcacctt gagcggggtc tgctcccagt
    23401 cgtcgtcggc atagccgccg aacaccccgg ccgcctcgcg gaccagcacg tcccgcggct
    23461 ccagcgcggc cagcgccccc ttggccgccg cctcgtccgc cgggccgtcg gcgggcagtg
    23521 ccaccggctc gtcgtccgcg tgcggcaccc gcagcgcggc cccgtccggg gccttgggct
    23581 ccccggaggc gcagaaccgg cagcgggggt gcggcagcag cggttcggcc agtacgtcca
    23641 gggagttcag gtcctgcacg atgacctggt tacgggtctc ggcgggcagc gcctccgtca
    23701 ccagccggaa cacctcgaac gacagcaggt tgccgagcat ccccgcgagc ggcccggtgg
    23761 gcactcgcgc gggcgtctcc agcggcgcgg ccggaccgag gccggaccac aggtcggcgc
    23821 tgtcggccgc gtccgagccg gcgcccagcc gcagcgcggc gcaggaccag cagcccggcg
    23881 tcccggccgt catcaccggc ccgaccaccg cccgctcgcc gaacgtccac gcccccagca
    23941 gccgccgtcc ctcgggcacg ccctcggtca gcaggcgcag cagccgggcg ggcgcgttcg
    24001 ccccggtcac cagcacggtg tcccagccgt ccaggtcggc ccagcccggc gtggacccgg
    24061 ccagccgggt cagcgtgggc gcgcagcccg cctcggtgag acccgcgacc tccgcgtcca
    24121 ggccggccgt gccgctgggc tcgtggtcga gggcgccctc cgccgcgtcc tcgaccgtga
    24181 cggccaccgt ggcacagccg ttgcgcagca ggcccagcgc ggcccacctc gccgtctcgt
    24241 cgtccccgag caccgcgacc cgggtgtccc ggaagcgggc gaacctgccg tgggcgtcgt
    24301 cggcgtaatg gtccagatag tccagctgat gggcgaaacg tgccgccacc tgcggtgaca
    24361 gcgtgtcgcc ggtgggtctt ggcccggcgt cccgggcgaa accacgcgcg tagagtgcgc
    24421 ccacgagtcg gaccaccatg tcgcgctgct tgtcccccag gccggcgcag agttcctcga
    24481 cccggcgctc accgtccaga tggggcacga tcagcgcggc gaagcggtac gcggactggg
    24541 tgacgacgtt gaagccgccg tgcgcgttgt ggaacagcac gccgtccggc gtgcgggtga
    24601 acaggacgtc gcggcggatg cggggccgcg aacgggcgat ctcctcgtgg gacgagggag
    24661 caggcgccat ggacaacctc cgggaagtac gggggagcgg tcagtcggcg gggggtgggg
    24721 acgtctccgc cgggtcgtgc ggtgcggtgg ccgggaggct ggtgccggcc gcctggacga
    24781 agagccgcag caggtcgtgg acccggtagc ggcccgacgg gtcctcctcc agcagcccgg
    24841 cgtccaccag tgcgcgcagc accagcgcgc ccggcgccgg gggagaggcc cgctccagcg
    24901 cggacgacgc cccggccgcc cttgagggcg gcacaccggc cgcgggcagc gccgggcgcc
    24961 cgccgtacgg ctcgccgcgc agcaccgcga gctggagcgc gcgcagcgcc gcacccggct
    25021 ccacccccag ctcggaggtg agatgggcgt ggatacggcg gtactccgcg agcgcctcgg
    25081 cccggcggcc cgagcggtac agcgcctcga tgagcagcgc cgacaatcct tcgtggccgg
    25141 gctggccgcg taccgcctcg cgggcctcgg cgatcatctc ccggtgtctg cccaggcgga
    25201 gttcgccgtc gaagacccgc tccacggcga gcagacgctc ctcggccagg cgcggcacgt
    25261 ggtcgcggtg cagttcgtcg gagtggacgt tgccgagcag cgggcccttc cacagtccca
    25321 gcgccgcccg cgccagccgc agcgcggcct ccgggtcgtc gccggccgag gcccggccga
    25381 gcaggtcgcg gaagtggagc aggtccaggg actcggcgtc cgcctggagc cgatagccgc
    25441 cgggcaccgc ctcgatggcg tggtcggcga ccccgtactt ggaaaacaga cggcgcagtc
    25501 ggagaacaca ggtgtgcagc gccgatctcc cgccggacgg cggacggtcg ccccacacca
    25561 cgcgctggag cagctcgccc gagaccacgg caccggggtg cagcagcagg gcggccagca
    25621 gtgaggtcgg tttggagggc tggaggacga cggtctcgtg accgtcggtg atggccagca
    25681 ggccgaggac ctggaaacgg gggcggcccg gatgcgccgc ggtggcctgc tgatcaggga
    25741 gggcgccgtg gggcgcggga agtccggtct tcaccacagc ctttcgcatc gcacggtgag
    25801 tgatgcagca actgcctggc acagcagggc acttgttcac accaggggtg taaggcgtga
    25861 acaagtgatc tgctgagacg ggaacttaga agcgaaccgg tcggtccgtc cagtggttgg
    25921 cgcgaaacac ctgatgacga gcggggggcg cggagacttt tgcgcccagc ggtgttggcg
    25981 ggcgccctgc cagggcatac cctcccggtg aagtggcgcg gcgcgctccc gtgaccgccg
    26041 cgcaggggag gaacaaccat gccgtggtgg gcgctggtgc cggtcgtctc gatgattacc
    26101 ggaccgctcg tgctgtatgt cctgagccgt cggaagcgtg actccgacga cgacgtcgaa
    26161 cggtacgagg agctgtccca caagtacgag gagctgcggg cggagaaccg gcggctcgaa
    26221 cccccggccg ccggggacca gcgcggctga accccggcga gcccggtccg ctcagccccg
    26281 ctgtcccacg cgctcggcgt gctcggacgg ctggtgctcg ctcatgtacc agccgtcgac
    26341 ccgcggcccg accaggtccg ccggccaccc cgcggtccgc acggccgcct cgtacacggc
    26401 gtcgccgaac ctgacgatcg ccccgtgcgg gtccggcagc cggcgcaggt tctgccacgg
    26461 cagcagcgcg agcccgaggt ccgggtgcca gtcggcgccc tcgacacccc aggaccgccc
    26521 cgccagaccg tccggctgcg gccagatgta ggcgtacatc ccgatgtcca gcgggctgct
    26581 gccgtcgccg tgggtgttgt cgaaggagaa ccccaccgac acgtactcgt gcagctgcgc
    26641 gttgcgcatg aacggggggc cctcgggtcc ggggtccgtc cgctcggggc gccagcgggt
    26701 cgccgacagg tcgaacccgc cccacatcac gccgacgcgc ggccggtgtc cgaggaaggg
    26761 ggcctgccac gcctccaggc cgcccgcggc gaggtcgaac gcctcccaga tcagccgcgc
    26821 cgagtgagcg tcccagaccc gctcggtccg gtcgtcctcg aagttcggcg gggcggcggg
    26881 gatctcgcag atccgcgcgc tgcgcgggtg cgggatgccc agctcggtgg cggcctcgca
    26941 gaaggacgcg aagaagtcgg ccaccgacgt ccgccccagc gacagcgtcc gcgccgcgcg
    27001 gtcggtctcg atcaccacgt ccccgtcgag cagccggtag tgcaccgtga aggtcacccc
    27061 gttccgccgg aacgtcgggg tacgcagccc gcgcggggac acctccagca cgatgttgcc
    27121 ccagccgacc tcgaaggggt cgtccagcga gtacttgccc gcgacctgca ccacccggtt
    27181 cacgtactcg agcatggggc ccagttccgc gtggtccagc accggccacg cctcgggacg
    27241 ttcgctcacg ggagcctccc ggcggatcga tccacgtgtt cccggcggcc gtacgacacc
    27301 ggcttcacaa acacccgatt tccggcatga cggtcgtacg atcgcacacc cccagattct
    27361 cccacgggcc ccggagcctc gcctccttcc cgcccgtgcc ggatcgcacc cgccgtgcca
    27421 cgatgacggg acagggtgac gggacacctc acctcagtac gccagttccg cggaagcgtc
    27481 cgaaggagcc cgacatggcg tcgacggaag cgaccggcgc ggccgggatg cagttcggca
    27541 tcttcaccgt cggggacgtc acccccgacc ccaccaccgg ccacaccccc accgaggcgg
    27601 agcgcatcca ggcgaccgtc gcgatcgcgc gcaaggcgga ggaggtcggg ctcgacgtct
    27661 tcgccaccgg cgagcaccac aacccgccct tcgtgccgtc ctcgcccacc accctgctcg
    27721 cgtacatcgc cgcgcagacc gaacggatca tcctctccac ctccaccacg ctgatcacca
    27781 ccagcgaccc ggtgaagatc gccgaggact tcagtgtgct ccagcacctg tccggcggcc
    27841 gcaccgacct catgctgggc cggggcaaca ccggcccggt gtacccgtgg ttcggccagg
    27901 acatccgcca ggccatcccg ctcacggtcg agaactacgg cctgctgcgc cgcctctggc
    27961 gcgaggagac cgtcgactgg gagggcacgt tccgcagcgc gctccagggc ttcaccctcg
    28021 tgccgcgtcc gctggacgac gtaccgccct tcgtctggca cgcctccatc cgcacccccg
    28081 agatcgccga actcgccgcc tacttcgggg acggcttctt cgccaaccac atcttctggc
    28141 cggcctcgca cacccgacag ctcgtcagcc tctaccggcg ccggttcgcg cactacgacc
    28201 acggcacccc ggagcaggcc atcgtggggc tcggcggcca ggtgttcatg cggcccaaca
    28261 gccaggacgc ggtgaaggag ttccggccct acttcgacaa cgccccggtg tacggacacg
    28321 ggccctcgct ggaggagttc acccggcaga ccccgctcac cgtcgggtcg ccggccgagg
    28381 tgatcgagaa gacgctgggc tttcgcgcat acgtggggga ctaccagcgg cagctcttcc
    28441 tcatcgacca cgccgggctc ccggtgaaga ccgtcctcga acagctcgac ctgctcggcg
    28501 aggaggtcgt ccctgtgctg cgccgggagt tcgccgaggg ccggcccgag ggcaccccgg
    28561 cggcccccac ccacgcctcg cgcctgcgcg cgcgcgagga cgcgaccgac gaaggcgaca
    28621 cggaggcgcg atgaagatca cgatcatcac gggcggactg cgcgagccct cctccacccg
    28681 gctcctcgcg gaccggctcg cggcggccgt cacccgggaa ctcgaggccg ggggcgagcc
    28741 ggtggagctg tccttcgtcg aactgcgccc gctggcgcat cccatcatgg acgcgatgct
    28801 caccggcttc accggcgagg cgctggacac ggccttcgag accatcgccg gggcggacgg
    28861 cgtcatcgcc gtgacccccg ccttcaacgc gtccttcagc gggctgttca agtcgttctt
    28921 cgacgtgctc cccgaggaga ccctctccga catgcccgtc ctcatcgcgg ccagcggcgg
    28981 caccgagcgg cactccctcg tcctcgaaca cgcgctgcgc ccgatgttct cctacctcca
    29041 cgcgatcgtc tccccgcgcc ccgtctacgc cgccaccagc gacttcggca cccaggacgg
    29101 cgcgagcctc ggcgcccgca tcaacgccgc cgccaccgac ttcgcccgcc tcctgcgcgc
    29161 ctgcggcccc cgcacccgcg aaacccagga ggacgcggac ctggcgacga tgcgggggct
    29221 gctgggcggc agctgaccgt cggccgccca aagcaacaaa tcaccacaca ggcaaaaccc
    29281 tgggcaagtc tgaagcaaca aatcttgacg tgttcgatcg tgcttcgtac gttcccgagc
    29341 ggccgtgagg agtcaccgac tccgcctccc caccacgcgg ccggccgaag gagcagacga
    29401 tgcgcgccat cagatcagcc gtgttaccag gtctccgcgg gcgcttcggg gccctggtgt
    29461 ccgtgctcgc cctgctgctc ggcgccctcg ccggactgag cgcccccgcc caggccgccg
    29521 ggtcggcgcc ctgtgacatc tacgccgccg ccggcacccc gtgcgtcgcc gcgcacagca
    29581 cgatccgggc gctgttcgcg ggctacaacg gcccgctgta ccgggtcacc cgtgcctcgg
    29641 acggcgccgc caccgacatc ggcctcctga cggccggcgg gtacgcggac gcgggccgcc
    29701 aggacacctt ctgcggcggc accacctgtc gtatgaccaa gatctacgac cagaccagcc
    29761 gccacaacga cctcaatccc ggcccggccg gcaccgccgg aatgggcgcc gaccgcgccg
    29821 ccgacgcgag tgaactcgcc gtcacggccg gcggccacaa ggtctacggc atctggatct
    29881 cgcccggcgt cggctaccgc tccaacggcg ccgcctccgg cgtcgcggtc aacggacagc
    29941 ccgagggcgt ctacatggtg gccagcggca cccacgtcgg ctccgcgtgc tgcttcgact
    30001 acggcaacgc cgagcgcacc cccgccgaca ccggcaacgg ccacatggac gccgtctcca
    30061 tcgccaccac ctgctacttc gccccctgca ccggcaacgg cccctgggtc gaggccgacc
    30121 tggagaacgg catgttccag ggcgacaacg gctccaaccc cgccaaccgg ggcaacagca
    30181 gcacctacgt caccgccgtg ctgaagaacg acggccagac ccggtacgcc ctcaagggcg
    30241 gcaactccca gtccggctcc ctgagcacct ggtgggacgg cgcgctgccc tcgcgcggcg
    30301 gctaccggcc catgcagcag gagggcggca tcatcctcgg taccggcggg gacaacagca
    30361 actggaacat gggcaccttc ttcgagggcg ccatggtctc gggctatccc tccgacgccg
    30421 ccgagaacgc ggtgcaggcc aacgtcgtcg cggccggcta ctccggccag accaacgtac
    30481 ccaacggccc ccagggcacc atcaccggcc ccggcggcaa gtgcgtggac gtcgccgccg
    30541 acgacaccgg ggtcaacggc gccgccgtcc agctctggga ctgccagacc tacgccgagg
    30601 accagcactg gacccacaac ccggacacct ctctcggcac catctcccgc tgcctggaca
    30661 tcaacgggaa cggcacggcc aacggcaccg aggtcgagct gtgggactgc gacggggtcg
    30721 ggggccagaa gtgggtccag caggccgacg gctcgctgcg caacccccag tccggccgct
    30781 gcctcgacgc gcccaacggc acctcggcca acggaacccg gctgcggatc tgggactgca
    30841 acggctccgc cgcccagaag ttctccgtca acggcggagc acccatcgcc gcgcccggcg
    30901 ccaagtgcgt cgacgtggcc gccgacgaca ccggggtcaa cggcaccgcc gtgcagctct
    30961 gggactgcca gacctggtcc gtcgaccagc actggttcca ccgctccgac tcctcgctct
    31021 ccaccctcgg ccgctgcctg gacgtcaacg gcaacggcac ggcgggcggc accgaggtcg
    31081 agctgtggga ctgcaacggg gccgggggcc agaagtggga gcagcaggcc gacggctcgc
    31141 tgcgcaaccc ccagtccggc cgctgcctgg acgcccccaa cggcacgacc ggcaacggca
    31201 cccggctgcg gatctgggac tgcaacggct cggccgccca gaagttccag ctgaactgac
    31261 ggcccggcgc cggggctttc cccgccggat acgggggaag cggctgcggg ggaggggtga
    31321 acacgcgggc ggacggcact tctccgcccg ccgcgccccg cccccgcaca ctaggaggtg
    31381 tcctgtcgat cacgccgggc tcgcgacgcc cggcaccgca cctcgccgcg ttgtcgtcgg
    31441 tccccgatgc tccgcgtcga ctccctcctc cgccgtgcga cgcacggcac cggacgccgc
    31501 tccccggtcc ggcctgatcg acaggacacc ccctaggcgc agccgccgca cccgtaccgg
    31561 aaggaacccc cgcaccatgc acctcgatct gagcggacgc accgccctgg tcaccggctc
    31621 cacgcagggc atcggcgcgg ccatcgcgct gggcctcgcc cgcgccggtg cccgcgtcgc
    31681 cgtcaacggc cgcgacaggg aacgtgtctc cgcgagcatc gccgagttcg ccacccaggc
    31741 cccggacgcg gagttcgtcg cggccgccgc cgacgtgtcc accgaggagg gcgcccggca
    31801 gttgctgcgg gagctgcccc aggtcgacat cctcgtcaac aacctcggca tcttcggcac
    31861 cgccgacccg ctggaactca ccgacgacga gtggcgccgc tacttcgaga tcaacgtcct
    31921 cgccgccgtc cggctcaccc ggctgtacct gcctggcatg accgaccggg gctggggacg
    31981 cgtgctgtac atcgccagcg actcggccat cgtcatcccg gccgagatga tccagtacgg
    32041 catgtccaag accgccctgc tcgcggtggg ccggggcttc gccaagaagg ccgcgggcac
    32101 cggcgtcacc gtcaactccg tcatcgcggg ccccacccac accgcgggcg tcgaggactt
    32161 cgtctaccaa ctcgtggaca aggacctgcc ctgggacgag gcccagcggg tcttcatgcg
    32221 cgaccaccgc ccgcagtccc tgatccagcg gctgatcgag cccgaggaga tcgccaacat
    32281 ggtcgtctac ctcagctccc cccaggcctc ggcgaccacc ggcggcgccc tccgcgtgga
    32341 cggcggctac gtggacgcca tcctcccctg accgtcccgc agccgggcgt gcaggcaccc
    32401 gtcgagagga aactcgggcg gcgcggcggg cagcaccccg gcccgctcga agccgcactt
    32461 gacagccacc cggcaggacg ccgtgttgtc catctggtgc agcagctcca gccgggtcag
    32521 cccccggccg aaggcccacc cggtcaacgc cgtcagcgcg cgcggggcca cgccccggcc
    32581 ccgcgcccgc gcggccgtcc agtaaccgac ctcggcccgg ccgtcccccg ggaccacgtc
    32641 cttgagcgtg atgtgcccca gcaactcgcc ttccgcgtca ggggagcagg gtgtgccggg
    32701 cgagccggcg gccacgacgg cgaaccccag acggtcgccc gtctcccagc cccgcgcctg
    32761 cccggcgatc cacgcgagcg cgcccgcctc gtcgtccacg gccgcccccg tccagcgccg
    32821 cagcgcggcg tcgccgcgct gcacccgcac cagttccgcc gcgtccgccg cccgccaggg
    32881 ccgcagcagc agagcatccc cgcgtatcac gcttccccct cggcccctcg cgtcccggcc
    32941 atgcttgcac acgagcccgg tggggcagat gaacccggac gcggactccc cgccggtgga
    33001 gcaggcgtgc ccgccgtacg ggcagcgggt gccgggccgg gtgggtccat tcgcccgtac
    33061 ggcccctgac gagccaaaat ggctccgagc gtttgaagaa acactgatgc ggaggagcgg
    33121 atccatggcg cacgagcgag ccggccgtcc ggccggtccc gaggaccttg tcgatgtggc
    33181 ccgcctggtg acggcgtact acgccctgca cccggacctg gccgaccccg cccagcgggt
    33241 cgccttcggc acctcgggac accggggctc gtccctggcg gccgcgttca acgaggacca
    33301 catcgccgcc accagccagg cgatctgcga gtaccgcgcc gaccagggca tcgacggccc
    33361 gctgttcctc ggggccgaca cccacgccct gtccgagccc gcgaaggtca ccgcgctgga
    33421 ggtgttcgcg gccaacggcg tcaccgtcct catcgacagc gaggacggct acacccccac
    33481 cccggccgtc tcgcacgcca tcctcgcgca caaccgggac cgcgcgaccg gcctcgcgga
    33541 cggcgtggtc gtgacccctt cgcacaaccc gcccgccgac ggcggcttca agtacaaccc
    33601 gccgagcggc ggcccggccc cctccgacgc cacctcgtgg atccaggacc gcgccaacca
    33661 gatcatcgcg ggcggcctca aggacgtacg ccgcatcccc tacgcccgcg cgctcgccgc
    33721 cgacaccacc ggccggtacg acttcctcgg cgcctacgtc cgcgacctgc ccagtgtgct
    33781 ggacctggcc ccgatccggg acgccggcct gcgcatcggc gccgacccgc tcggcggcgc
    33841 ctccgtcggc tactggggcc ggatcgccga cgagcacggc atcgacctga ccgtggtcaa
    33901 cccgcacgcc gaccccacct ggcgcttcat gacgctggac tgggacggca agatccgcat
    33961 ggactgctcc tcgccgtacg cgatggcctc gctcatcgag cagcgcgacc ggttcggcat
    34021 ctccaccggc aacgacgccg acgccgaccg gcacggcatc gtcaccccgg acgccgggct
    34081 gatgaacccc aaccactacc tcgccgtcgc catcgactac ctctaccgcc accgcgacca
    34141 gtggccggag gcgaccggga tcggcaagac cctggtgtcc tccacgatga tcgaccgggt
    34201 cgccggcgac ctgggccgca ggctcgtcga agtgccggtc ggcttcaagt ggttcgtgga
    34261 cggactgctc agcggggacc tcggcttcgg cggcgaggag tcggcgggcg cctccttcct
    34321 gcgccgtgac ggctcggtgt ggaccaccga caaggacggc atccttctcg ccctcctggc
    34381 ctccgagatc accgccgtca ccggccgcac cccctccgag cactacgccg gactcaccga
    34441 gcgcttcggc gagcccgcgt acgcccgcat cgacgccccg gcgacccgcg agcagaaggc
    34501 gctgctcgcc aagctgtccc cggcccaggt caccgccgac accctggccg gtgaggaggt
    34561 caccgccgtc ctcaccgagg cgcccggcaa cggcgccccc atcggcggca tcaaggtcac
    34621 caccgccaac gcctggttcg ccgcccgtcc ctcgggcacc gaggacgtgt
//
