LOCUS       NZ_SHKU01000001        20981 bp    DNA     linear   CON 27-MAY-2024
DEFINITION  Streptomyces sp. BK022 Ga0307664_101, whole genome shotgun sequence.
ACCESSION   NZ_SHKU01000001
VERSION     NZ_SHKU01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. BK022
  ORGANISM  Streptomyces sp. BK022
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 1305487)
  AUTHORS   Kalluri,U.
  TITLE     Understanding the reciprocal impacts of modified plant cell wall and
            associated microbiome
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1305487)
  AUTHORS   Kalluri,U., Huntemann,M., Clum,A., Pillay,M., Palaniappan,K.,
            Varghese,N., Mikhailova,N., Stamatis,D., Reddy,T., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-FEB-2019) Prokaryotic Super Group, DOE Joint Genome
            Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.12.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 215.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004217355.1-RS_2024_05_27
            Annotation Date                   :: 05/27/2024 02:58:00
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,482
            CDSs (total)                      :: 6,401
            Genes (coding)                    :: 6,280
            CDSs (with protein)               :: 6,280
            Genes (RNA)                       :: 81
            rRNAs                             :: 5, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 16S)
            partial rRNAs                     :: 3, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 121
            CDSs (without protein)            :: 121
            Pseudo Genes (ambiguous residues) :: 0 of 121
            Pseudo Genes (frameshifted)       :: 49 of 121
            Pseudo Genes (incomplete)         :: 92 of 121
            Pseudo Genes (internal stop)      :: 16 of 121
            Pseudo Genes (multiple problems)  :: 29 of 121
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:05:10
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 383064
            Orig. end                         :: 404045
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            SHKU01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20981
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="nucleoside"
                     /region_number="4"
                     /rules="(LipM or LipV or LipU or TunD or pur6 or pur10 or
                     nikJ or nikO or truD)"
                     /tool="antismash"
     cand_cluster    1..20981
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(LipM or LipV or LipU or TunD or pur6 or
                     pur10 or nikJ or nikO or truD)"
                     /kind="single"
                     /product="nucleoside"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20981
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:10981](+)"
                     /cutoff="20000"
                     /detection_rule="(LipM or LipV or LipU or TunD or pur6 or
                     pur10 or nikJ or nikO or truD)"
                     /neighbourhood="10000"
                     /product="nucleoside"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10981
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(LipM or LipV or LipU or TunD or pur6 or
                     pur10 or nikJ or nikO or truD)"
                     /neighbourhood="10000"
                     /product="nucleoside"
                     /protocluster_number="1"
     gene            943..1944
                     /locus_tag="EV284_RS01815"
                     /old_locus_tag="EV284_0369"
     CDS             943..1944
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003961867.1"
                     /locus_tag="EV284_RS01815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_0369"
                     /product="radical SAM protein"
                     /protein_id="WP_242625504.1"
                     /sec_met_domain="PF04055 (E-value: 1.9e-16, bitscore: 57.1,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 1.8e-06, bitscore: 23.7,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRASLDVTYACDLRCIHCRTNTGEIPVHIRRRMLSIEQIQEVMLD
                     LDRMETFEITLTGGEPTIRKGFWDLLDVIPKLKHSTVTLITNAANLTREQMDRIIDSGI
                     SSLRVSMDGTRETFEAVRLVDRYNQVMENSTYLRDRVDSFKVLTTVMKTNQHNVFALVE
                     DLRLHGFRRQDLILVRSHGRGGRNRLLLTETETMELHRKVQDFRRRVPAIDFDLNLNAP
                     YLVPGEKLTSHQDVVMFPYLVKDTSVAISATGDVTMSRLYSAHPLGNVKEAAIARIWEE
                     GQDQLVREQEGFTDDKLREIFWDFAAAETPDSAPVMLTSLLDRQLFEGYEVR"
     gene            2000..2434
                     /locus_tag="EV284_RS01820"
                     /old_locus_tag="EV284_0370"
     CDS             2000..2434
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070967 - coenzyme F420 binding [Evidence
                     IEA]"
                     /GO_process="GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR03618.1"
                     /locus_tag="EV284_RS01820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_0370"
                     /product="TIGR03618 family F420-dependent PPOX class
                     oxidoreductase"
                     /protein_id="WP_130329570.1"
                     /transl_table=11
                     /translation="MPKDYTWTPPVPSDNLTLPTEVGPWLEAGACATVATVEPDGRPQL
                     SVVWAHYTERDVLFATVKGRRKYDNIVRNPFVTVLITPLDSQDHYVEIRGRAQIEDGGR
                     QLIDFLHERHRGTRPYPWDGPNDERVVVRVVPDRVLVFHG"
     gene            2723..3832
                     /locus_tag="EV284_RS01825"
                     /old_locus_tag="EV284_0371"
     CDS             2723..3832
                     /codon_start=1
                     /gene_functions="regulatory (extras) StrR_like: StrR-like
                     pathway specfic regulators"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014273.4"
                     /locus_tag="EV284_RS01825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_0371"
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="WP_130329572.1"
                     /transl_table=11
                     /translation="MGIAALNMENRKDAASEDVIYRISNSIGISDGSAKPVVSVAIADL
                     LPADSPRLTGENAEHIIMLADSGMKLPPIIVHRTTMRVIDGMHRLGAALRRGSQRIDAL
                     LVDNTEEEDLFILTVQANIAHGLPLTLADRQSAAARIILSHSQWSDRSIAKVTGLAPKT
                     VRAIREQTPGASSPSHVRLGQDGKARPLTAAVGRKRAGEILTANPGASLRQVAKDAGIS
                     LGTAFDVRKRLVNGEEPVVPPEKCGPPQDGEQDDPPEHLKKNVRRARIDEPSSTRVREG
                     GLKKQVVTRDPSMLINVLMRDPSLRFTDSGRLLLRWLSSRGISPAEYGEMIESVPPHCT
                     GAVVDYARLVAEFWTQFADQLDQRERAMA"
     gene            4208..6583
                     /gene="hypF"
                     /locus_tag="EV284_RS01830"
                     /old_locus_tag="EV284_0372"
     CDS             4208..6583
                     /EC_number="6.1.2.-"
                     /GO_function="GO:0003998 - acylphosphatase activity
                     [Evidence IEA]"
                     /GO_process="GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hypF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006350691.1"
                     /locus_tag="EV284_RS01830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_0372"
                     /product="carbamoyltransferase HypF"
                     /protein_id="WP_130329574.1"
                     /transl_table=11
                     /translation="MAEVMERRRVSVRGVVQGVGFRPFVYLQARELGLAGFVGNNAHGV
                     FIEVEGTAEDIDGFIERIHSDSPPLSQIDGISQHLIPALGETEFVIAPSTQGEMARNAL
                     VSPDSAVCGDCLREMLSPEDRRFAYPFINCTNCGPRFTITRDVPYDRANTTMARFALCQ
                     ECAHEYGDPGDRRFHAQPNACPACGPRVEFHDFTSCVPAGRAGPPGGSAAFCQAADVLG
                     RGGVIGVKGIGGFHLVCDATDDAAVVKLRRHKDREAKPLAVMVADIASAEELCHVSEEE
                     AALLQSSARPIVLLRRRDQAMVSSAVAPDTSALGVMLAYTPLHHLLLAAHRSASGGDRR
                     STLVMTSANSSDDPIVYRDEEALRLLEHVADGALLHDRDIHMRCDDSLVRVHQGRRQVL
                     RRARGYAPAPLKLAFSSPVPLLAYGAHNKNTFCLVKSDDAFISHHIGALRSPGTLKSLR
                     ETVQHYQQLFGVTPQVAVHDYHPQYQSTRLALQSDVPVKMSVQHHEAHIASVIAEHGID
                     GPVIGVAADGAGYGPDGTIWGGEFLIGDLTSFSRFAYLEPVSLPGGDSSVKRPWMLGVV
                     HMENAFGTEFAALPVQFTKSLDTASLERLGRVAHDPRLSPRTSSMGRLFDAVSAILGLS
                     SEIHYEGQAAILLEEQAWRFRNGTRGGRMSAPVKPFAVEVNASGGPIQLGPLIRDLVDD
                     LVDGRPEEEVAFRFHLSVAELIVAACEAARRQSGIQQVALSGGVFQNTLLLDMVANGLQ
                     RHSFSVFTNEKVPPNDGGLSLGQAAIAASRLRSIRAVQ"
     gene            complement(7144..7497)
                     /locus_tag="EV284_RS01835"
     CDS             complement(7144..7497)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EV284_RS01835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_130329576.1"
                     /transl_table=11
                     /translation="MRSCQAKSSELGELGQVTDALTGPGGMLETVRAAQGDVSEVAVEL
                     RCDIAMLPLLQGRSAETPSCGSGATAPMRTGADGHLGDLVRKPEVAGPMLADGKRIRPA
                     HTPSTSPTSRRLS"
     misc_feature    complement(7887..7902)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.38"
                     /tool="antismash"
     misc_feature    complement(7964..7978)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 18.06"
                     /tool="antismash"
     misc_feature    complement(9775..9786)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.76"
                     /tool="antismash"
     gene            10001..10981
                     /locus_tag="EV284_RS01845"
                     /old_locus_tag="EV284_0375"
     CDS             10001..10981
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (67-220). E-value:
                     1.6e-08. Score: 25.9. Matches aSDomain:
                     nrpspksdomains_EV284_RS01845_NAD_binding_4.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     nucleoside: TunD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010045814.1"
                     /locus_tag="EV284_RS01845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_0375"
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="WP_242625505.1"
                     /sec_met_domain="TunD (E-value: 4.1e-121, bitscore: 400.0,
                     seeds: 3, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 2.3e-10, bitscore:
                     36.2, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 3.8e-09,
                     bitscore: 32.2, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLESKRKKFSTALITGGAGFIGGHLARALRQDGTTVRSVDDLRVA
                     PLIKPDGNLLIKRVSDLTVDDVEGVDVVYHLASDKSVPLSFEAPLQYLENLESTEHLLR
                     LCAVVDVPRVIIASTCEVYGRARTRPTPENEPLAPLSPYAASKVAMEMVARVHRHSAPL
                     RNRVSVVRFFNVFGPGERPDAVIPRFCLGALTDGLLPVEGAGTQRRDFSFIDDVVDVLR
                     RMPMAEPVPVINIGSGFTVSVLEIAEAIKGFCPRAEVKHVGGRQEEIPEFWADTAAQRT
                     LVARPAVHADVREGIRKTLDWWASTSLVQNTVAGGWDGEDQPLLI"
     CDS_motif       10037..10087
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EV284_RS01845_0001"
                     /evalue="6.90E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="EV284_RS01845"
                     /protein_end="29"
                     /protein_start="12"
                     /score="12.3"
                     /tool="antismash"
                     /translation="LITGGAGFIGGHLARAL"
     aSDomain        10202..10660
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EV284_RS01845_NAD_binding_4.1"
                     /evalue="1.60E-08"
                     /label="EV284_RS01845_NAD_binding_4.1"
                     /locus_tag="EV284_RS01845"
                     /protein_end="220"
                     /protein_start="67"
                     /score="25.9"
                     /tool="antismash"
                     /translation="EGVDVVYHLASDKSVPLSFEAPLQYLENLESTEHLLRLCAVVDVP
                     RVIIASTCEVYGRARTRPTPENEPLAPLSPYAASKVAMEMVARVHRHSAPLRNRVSVVR
                     FFNVFGPGERPDAVIPRFCLGALTDGLLPVEGAGTQRRDFSFIDDVVDV"
     gene            11055..12839
                     /locus_tag="EV284_RS01850"
                     /old_locus_tag="EV284_0376"
     CDS             11055..12839
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="EV284_RS01850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_0376"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_130329580.1"
                     /transl_table=11
                     /translation="MLRNASRWSIAGILASFFLLAVLPPVSALITGGLVQSVIEAESGG
                     SHGEVWVMLSAFAVVTVAGWCISTLISPLTSLATRQAEGFVHDRLFALGEQSRLFPHLE
                     TSAFADDVSRVVDSTDGPNRCLGLGAVTQIENLSKLLGAICLGLVIARVSVLLALLLIV
                     TVFAIRHSLVKGLSIGLTRMDEQVRARRRGQYLYDLVSTAASGKEVRTFGLGTWLVDRF
                     RKEMHDYHQSIFLLRRGLARREGRLLPVLMVVSGAAFLWPAVAALHGRVSVNVMTSVVM
                     ACLSLFTTLQAGQEQMYITPARLALRALGRIEAVADEVRRSMSETVPAPSDGAPLIRFS
                     GVRFGYNRRVPVLNGLDLEVKPGEVLAIVGVNGVGKTTLTKLLAGLYQPEEGRITADGI
                     EVGLIDSEQWHAHLAVVFQDFVKYPLSARENIVLAAPALAGDEELIRRVVEEAGVSALL
                     AALPNGLDTPLSSERTGGVDLSGGQWQKIAIARALFAVRAGARVLILDEPTAHLDIRAE
                     AAFFSEVVGRISGVSTILISHRLSTVRQADRIVLLDQGRVAESGTHDQLLALNGQYSEM
                     FHLQAARFKEMNTADGAA"
     misc_feature    12916..12934
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 21.99"
                     /tool="antismash"
     gene            12920..14662
                     /locus_tag="EV284_RS01855"
                     /old_locus_tag="EV284_0377"
     CDS             12920..14662
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="EV284_RS01855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_0377"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_130329582.1"
                     /transl_table=11
                     /translation="MRLAFRANRKAAVALLIIMAVNAVGTSAIGLALERLVNSVTKGTL
                     SGVILAAALGALCLALLEVGFRVQFSLRLEVSARVNVLVQEEIATAAATLTTLEHLEDP
                     AYLDRITVLRQDSEWLADFCWTLLETVAIIVQISVAVALLALVSPPLTALLVLAFPPVL
                     LTRRAQRIAQRAAEDAAEDARLSARLLTMSTRSDSLKEICVNNAAPALRAKAAQAWGSS
                     TRTRARGEFRSAALNLCGFLIFTVGFLGALAYAVAEALSGHGTAGGVILVITLAGRLQA
                     QVGHGVWLIGRLTKSMLVADRYVWLRQRLAADTRAGLPAPRKIERGVVLDGVSFRYTGG
                     TEDVLRDVNLEIPAGSVVAVVGENGAGKTTLVKLLSKFYSPTAGSIRFDDVDLTDIDTV
                     DWRRSMSAAYQDYARLEFLIRESVGLGEIGSINDDGAIHRALRKADSDEWVSELEHGLN
                     TRLGTTFDGVDLSLGQWQRLALARSSMRSGPLLLVLDEPTASLDARTEHDQYERFAALA
                     KEVGQATGAVTLLVSHRFSTVQTADLIAVVKGGEIAEFGSHHELMEANGFYSEMYRVQA
                     QAYS"
     misc_feature    complement(14711..14724)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 22.38"
                     /tool="antismash"
     misc_feature    14847..14861
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.88"
                     /tool="antismash"
     gene            15057..15575
                     /locus_tag="EV284_RS01860"
                     /old_locus_tag="EV284_0378"
     CDS             15057..15575
                     /NRPS_PKS="Domain: PCP (96-164). E-value: 5.8e-16. Score:
                     50.5. Matches aSDomain: nrpspksdomains_EV284_RS01860_PCP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012759.4"
                     /locus_tag="EV284_RS01860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_0378"
                     /product="phosphopantetheine-binding protein"
                     /protein_id="WP_165425436.1"
                     /sec_met_domain="PP-binding (E-value: 4.8e-09, bitscore:
                     32.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDDLLRAVGDHAEITGFRAMSGASGSRPLIVMTTTGFLGGPELRR
                     HCHEQGTVADFDTLTVDDVVLDLLSPDELSKLVTNSSEGAFSRFVTPEGDLETQLVTMW
                     ESLLDFTPIGVLDDFVELGGESMSALEIVVQVSQRWGRDLNLVDVVDAACIRNLARLIT
                     ASPANADET"
     aSDomain        15345..15548
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EV284_RS01860_PCP.1"
                     /evalue="5.80E-16"
                     /label="EV284_RS01860_PCP.1"
                     /locus_tag="EV284_RS01860"
                     /protein_end="164"
                     /protein_start="96"
                     /score="50.5"
                     /tool="antismash"
                     /translation="ETQLVTMWESLLDFTPIGVLDDFVELGGESMSALEIVVQVSQRWG
                     RDLNLVDVVDAACIRNLARLITA"
     gene            15580..16452
                     /locus_tag="EV284_RS01865"
                     /old_locus_tag="EV284_0379"
     CDS             15580..16452
                     /EC_number="3.1.3.48"
                     /GO_function="GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024744.4"
                     /locus_tag="EV284_RS01865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_0379"
                     /product="tyrosine-protein phosphatase"
                     /protein_id="WP_165425437.1"
                     /transl_table=11
                     /translation="MSGDTAPSDRIPAVDMPPGRSDLAPELRGMCNFRDLGGLRRTDGT
                     RLPSGWLFRSDAPTADSAADLDRIRALGIRTIVDLRSAEEQPSCPPALRSTCAYVSMPI
                     DRVEWADSALASEDMADFLAGRYLRLAAQCLTDDDRHLGSALNVLGLPCDQPRIVWCAG
                     GKDRTGLVTAILLRLLGVTDDDIRADYARSSFAAAELRRRARVETPAKAGRAVSPEERR
                     AALRGRLASFSEGIGRLSNPAPPEAIGLFLASLSARRGGVESYAASVGADMETIAMTRR
                     WLSALAVAP"
     gene            16494..16928
                     /locus_tag="EV284_RS01870"
                     /old_locus_tag="EV284_0380"
     CDS             16494..16928
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EV284_RS01870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EV284_0380"
                     /product="hypothetical protein"
                     /protein_id="WP_130329588.1"
                     /transl_table=11
                     /translation="MKILISVSDQVWGRKDQYVIDAIIGLLAYGHAVCPAVEEGGTMAA
                     ELTRRVISQMRVSAFCANPREAAEADVRWRDETGSGFVFVPVNSPNTELPATNHLLVKA
                     VLTAQRAEDPLKLSAGRDRDLVNLFYAVGALVPNRPKAMC"
     gene            16928..17908
                     /gene="galE"
                     /locus_tag="EV284_RS01875"
                     /old_locus_tag="EV284_0381"
     CDS             16928..17908
                     /EC_number="5.1.3.2"
                     /GO_function="GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (66-188). E-value:
                     9.9e-11. Score: 33.1. Matches aSDomain:
                     nrpspksdomains_EV284_RS01875_NAD_binding_4.1"
                     /codon_start=1
                     /gene="galE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010045806.1"
                     /locus_tag="EV284_RS01875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_0381"
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="WP_130329590.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 7.6e-20, bitscore:
                     67.3, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 1.4e-13,
                     bitscore: 46.7, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVLVTGGAGYVGSFVVRHLLERNHDVRVLDDLSTGRAEAVPDIA
                     PDIVNIRHAQDVAAVVRSFAPEAIIHLAGLKSSAESVQRPDLYYDVNVTGTSALLRAAK
                     RHGVERFVFSSSCAVYGSPQVCPVDEHAPTEPQSPYGETKLACERMLQWHARVTGMRWA
                     ALRYFNVAGAAADGSLGEFTGPHTVQLVPLAIKAARSGVPLKIYGGDYPTFDGTAVRDY
                     LHVVDLAEAHVRLIEGLETPELSGVYNLGTGRPASVLEIVKMIEQVSGCPVPYHLAPRR
                     NGDPAFSWADSEHARRTFDWVPQRKLDEIVRSAWLWHSSGRSGEA"
     CDS_motif       16937..16996
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EV284_RS01875_0001"
                     /evalue="4.90E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="EV284_RS01875"
                     /protein_end="23"
                     /protein_start="3"
                     /score="12.8"
                     /tool="antismash"
                     /translation="LVTGGAGYVGSFVVRHLLER"
     aSDomain        17126..17491
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EV284_RS01875_NAD_binding_4.1"
                     /evalue="9.90E-11"
                     /label="EV284_RS01875_NAD_binding_4.1"
                     /locus_tag="EV284_RS01875"
                     /protein_end="188"
                     /protein_start="66"
                     /score="33.1"
                     /tool="antismash"
                     /translation="EAIIHLAGLKSSAESVQRPDLYYDVNVTGTSALLRAAKRHGVERF
                     VFSSSCAVYGSPQVCPVDEHAPTEPQSPYGETKLACERMLQWHARVTGMRWAALRYFNV
                     AGAAADGSLGEFTGPHTV"
     gene            17908..18513
                     /locus_tag="EV284_RS01880"
                     /old_locus_tag="EV284_0382"
     CDS             17908..18513
                     /EC_number="3.1.3.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1101: phosphoglycerate mutase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012521.4"
                     /locus_tag="EV284_RS01880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_0382"
                     /product="histidine phosphatase family protein"
                     /protein_id="WP_165425438.1"
                     /transl_table=11
                     /translation="MDLLLIRHAHDDRVGPHARRLSALGRAQCAALAKTLIGSRVDELW
                     TSPRSRAVETAREISRTLRLPLRTDPRIEEIRTARPEDPDVLPPRERVGVTLADGTEDW
                     NAFLDRVSAFVSERCLGSHDDRTVAVVTHSGVFDAVHEVLTGSGRRIELEIAHTGFTTW
                     RHRPGSSAGTWLLRRHNDVAHLAREGLLTDADQVERRP"
     gene            18513..20069
                     /locus_tag="EV284_RS01885"
                     /old_locus_tag="EV284_0383"
     CDS             18513..20069
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003961862.1"
                     /locus_tag="EV284_RS01885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_0383"
                     /product="alkaline phosphatase family protein"
                     /protein_id="WP_130329594.1"
                     /transl_table=11
                     /translation="MSQYRGPRLVVLCVDGGLPSVVGTWNFFSPHRRLPDSHDSGATAL
                     RSVFPSSTAPAHASFLTGAHPTEHGVIGNRYWTGEPVAEICRRAANPLLTLHPYDAASL
                     TAPSLVEWLADQGARVAAVHFPQTFSQIAPSRAVSSLYCLYAPARRVLVPLADGTDRET
                     VQAVYFDESLPLTARVPSGGGAQTVMFSIGTAGPETAVPVAGRTVQVDARITEGNLSVP
                     VRCEKVAHGTAELVLGTAVLTLSFGAVAARDLRFPGCGGPSSLGIEYTANPEHDFHESP
                     SAPWIRDSALDIVAKDEPDVLFLRFNQADHAQEFLYWYAARSGGREAALAREQILSSYQ
                     TIDACVGDIMREVGDQADYVLFSDHGIDYVETHLQPNVVLRELGLDTGMIFQGDSNIAY
                     LYADRPVSQTDRRRIINALAAVDTTVRPADAVSHAVRLPSAPGRTGELLITCGPHREFD
                     YGFSGPAGVAVRSASHGYFPSYPAMNGFFRMFGPRTAGHEAPGAITDVADLVKNLWLRG
                     Q"
ORIGIN
        1 acacagaacc ccgcacacta cttcgacgtc aacgtgtcgg gcaccgtcaa ccttctcaag
       61 gccgcgtccc ggtacggcgt cgtccgcttc gtcttctcgt cgtcagcagc cgtgtacggc
      121 acgccgcaga tgtgtccggt cgacgaaacg gcacctactg cgccgcagag cccgtacggc
      181 gagtccaagt acatcggtga gcgcctggtg accacacagg cggccaccac cggcatgcgc
      241 cacgcctgcc tacgttattt caacgtggcg ggcgcggcac cggacgcgtc acttggcgag
      301 tacgcgtccg gcgaggcacg gcagctcgtg ccgcgcgccg tcgccgtggc acgcggcttg
      361 gcgccgacgc tgaagatatt cggcacggac tacccgacag aggacgggac agcgctgcgc
      421 gactacatcc acgtggtcga cctcgcacgc gcccatgtgt tggtcgccga ggggctggac
      481 gacgccggac gctgcgggac gtacaacctg ggccgaggcg aaggcaccag cgtgctcgcg
      541 ttggtggacg ggctgcggcg gatcagtggc gcggaggtgc ccgtggagcc ctgttcccgt
      601 cggcccggcg acatgccggc atcgtgggcc gacgccggac tggtgttccg cacgttcggc
      661 tggcgagccg agtgcgacct gcacgacata ctcagctcgg catgggcgtg gcacaacggc
      721 gcgccgcgca cggggtgagg cggacgtgac ctcccgtgcc accagggtcg cttcggcaga
      781 cgacgaccgg ctctacgaga tccgctcggg ccctagggca acgcacgaat gcccggaccc
      841 cgtgaaagcg atctatgcgt ggtgaaaagt tcagctcatg accgagatct tcaccgaaga
      901 cccgaacaag gagttcgccc gatgagtagg tatcgcggac ccgtgcgcgc cagtctggac
      961 gtcacctacg catgtgacct ccgctgcatc cattgccgca ccaacactgg cgagatcccg
     1021 gtgcacatac gccggcggat gctgtcgatc gagcagatcc aggaggtcat gctcgacctc
     1081 gaccgaatgg agacgttcga aatcaccctg accggtggcg aaccgaccat ccgcaagggg
     1141 ttctgggacc tcctggacgt gattcccaag ctcaagcact ccacggtcac gctcatcacc
     1201 aatgcggcca acctgactcg tgagcagatg gaccgcatca tcgacagcgg catctcctca
     1261 ctcagggtca gcatggatgg cacccgggag acgttcgagg cggtccgcct cgtcgaccgc
     1321 tacaaccagg tcatggagaa ctcgacgtac ctgcgtgatc gtgtcgacag cttcaaggtg
     1381 ctgaccacag tgatgaagac gaatcagcac aacgtcttcg cgctcgtcga ggacctccgc
     1441 ctgcacggat tccggcgaca ggacctcatt ctggtccggt cccatggccg cggcggacgc
     1501 aaccggctgc tgctgacgga gaccgagact atggagctgc accgaaaggt ccaggatttc
     1561 cgtcgccggg taccggcgat cgacttcgac ctgaacctca acgcccccta tctggtaccg
     1621 ggtgagaaac tgacctcgca tcaggacgta gtgatgtttc cctacttggt gaaggacacc
     1681 agcgtcgcca tctcggcgac cggcgatgtc accatgagcc ggctctacag cgcccacccc
     1741 ctgggcaacg tcaaggaggc cgcgattgcg cgcatttggg aggaggggca ggaccagctg
     1801 gtacgggaac aggaggggtt caccgacgac aaactgcgcg agatcttctg ggatttcgcg
     1861 gcggcggaga ctccggacag tgcccccgtg atgctcacct cactcctgga ccgacagctg
     1921 ttcgaggggt acgaggtccg ttgacctcgc gcctcactgc ccgtcatgtt ctcgataccg
     1981 agcagtaagg aaagaatcca tgccgaagga ctacacctgg actcctccgg tcccgagtga
     2041 caacctgacc ctgccgacgg aggtcgggcc atggctcgaa gcgggggcat gcgccacggt
     2101 agccacggtc gaacccgacg gccgcccgca actctcggtg gtgtgggcgc actacaccga
     2161 gcgcgacgta ctgttcgcga ccgtcaaggg ccgtcgcaag tacgacaaca tcgtgcgcaa
     2221 cccctttgtg accgtgctga tcacgccgct ggatagccag gaccattacg tggagatccg
     2281 cggccgggcc cagatcgagg acggaggccg gcagctgatc gatttcttgc acgagcggca
     2341 ccgtggcacc cgtccgtatc cctgggatgg ccccaacgac gagcgagtgg tcgtccgagt
     2401 cgtgcccgat cgcgtcctcg tcttccacgg ctgaccacca acgaccggac gggcggtcgc
     2461 gggaccgaca ccccggcgac tgcgggtgga agcacctttc ctctccgggg atcttcaagc
     2521 tccgcttggc acacggccac agggcgctca atggacggat cagcatgagc ttccccgtca
     2581 aggcgggcat gaaagcacat tgaaaacgtg tccgtctgtc accgacccct aatcaagagg
     2641 aaaacatgga tcccagagac ataggcatcg aagcggttgc ccagacgatc ctgaaccatg
     2701 acgcggcgga ggagggaaaa ccgtggggat agctgctttg aatatggaaa accgtaaaga
     2761 tgcggccagc gaggatgtta tttatcgaat ctccaactcg atcggtatat ctgacggaag
     2821 cgcgaagccg gttgtctctg ttgccattgc tgatctacta cccgctgact caccccggct
     2881 gaccggggaa aacgcagaac acataattat gcttgccgat tcggggatga aacttccacc
     2941 gatcatcgtg catcggacta cgatgcgtgt gatcgatggg atgcacaggc ttggtgctgc
     3001 actacgacgc ggttctcagc gaattgacgc actactggtc gataacaccg aggaagagga
     3061 tctgttcatc ctcacggtgc aagcgaacat tgcgcatggc ctaccgctca cactggccga
     3121 ccggcagtcg gcagcggctc gtattatcct gtcccattca caatggtcgg atcgctctat
     3181 tgcaaaagtg acgggtctgg ctccgaaaac agtgcgggcc atccgcgagc agacgccagg
     3241 agcttcttcg ccatcgcacg tcaggctcgg tcaggatggc aaagctcgac cgttgaccgc
     3301 tgctgtggga cgcaagagag ccggcgagat tctcaccgct aatccgggtg cttcgctacg
     3361 gcaggttgcc aaggacgcgg gaatctcgct cgggactgca tttgatgtac ggaaacggct
     3421 agtgaacggc gaagagccgg tggtgccgcc tgagaaatgc ggcccaccgc aagacgggga
     3481 acaggacgat ccgccagagc atttgaagaa gaacgtgcgc agggctcgaa tcgatgagcc
     3541 atcttcgacg cgggtacgcg agggtgggct gaaaaaacag gtggtgaccc gggatccttc
     3601 aatgctcata aatgtcctga tgagggatcc atccttgcgt tttactgatt ccggtcgact
     3661 tctgctgcgc tggctgagca gtcgaggaat aagcccggcg gagtatggag agatgatcga
     3721 gagtgtgccc ccgcactgta ctggcgccgt agtcgactac gcacgtctgg ttgcggagtt
     3781 ctggacgcaa tttgccgacc agttggacca acgcgagcgc gcgatggcat gatcgaggca
     3841 tttgcgcgga tatttccggg aagggaatcg ccgatgagtt gcgcgaccgt ttcaatctga
     3901 ccggacagtg ctctgaccaa gtgcatcggt gggtgttcaa ctgcgtacat tccccggttg
     3961 aacaggcggc agcgggccgg ccgcccgtcg ggacggcact ctcggttggg gcgatggttc
     4021 gcgatacggc cgctctcccc cgaactggcg ctcacagccg agttccagac agccctgcgt
     4081 cgcacgatgc ctgtaacagg aatctatgag gcttcaaaag gatcgcatgg aacccgaaat
     4141 cggccgatgg tcctcacgga ctggccctga ggtcgggaaa ttccccgcca gcagcggagg
     4201 tcaagggatg gcggaagtca tggagcgtcg gcgtgtcagc gttcgggggg tcgtccaggg
     4261 ggtcggcttt cgcccgttcg tctatttgca ggcccgtgag ctcggcctcg caggtttcgt
     4321 cgggaacaac gctcatggcg tgttcatcga ggtggaggga acagcagagg atatcgatgg
     4381 ttttatcgag cggattcaca gcgattctcc gccgctgtcc cagattgatg ggatatcgca
     4441 gcacctgatc cccgcccttg gcgagacaga gttcgtgatc gccccgagca cgcagggtga
     4501 aatggcgcgg aatgcccttg tctcccccga ctccgcggtc tgtggggact gtctccgcga
     4561 gatgctatcg cccgaagacc ggcgtttcgc ttacccattc atcaactgta caaactgcgg
     4621 tccccgtttc actatcactc gggacgttcc gtatgatcgc gcgaacacca caatggcgcg
     4681 gttcgcgctc tgtcaagagt gtgcccatga atacggtgac cccggcgacc ggagattcca
     4741 cgcgcaaccc aacgcatgcc cggcgtgcgg cccccgcgtt gagttccacg acttcacctc
     4801 ttgcgtccct gcaggcaggg ccggcccccc gggcggttcc gccgccttct gtcaggctgc
     4861 ggacgtcctt ggccgcggcg gcgtaatcgg tgtgaagggg atcggcggtt tccatctggt
     4921 gtgcgacgcg acagatgatg cggcggtggt gaagttgcgg cgccacaagg accgagaggc
     4981 caagccgctt gcggtgatgg ttgctgatat tgcctccgct gaggaactgt gccacgtgtc
     5041 ggaggaggag gcggctctgc ttcagtcgtc ggcacggcct attgtcctgc tgcgccggcg
     5101 tgatcaggcc atggtgtcga gcgcggtagc cccggacacg agcgcactcg gcgtcatgtt
     5161 ggcctacact ccactccacc atctgctgct ggccgcgcat cgctctgcgt ctggcggtga
     5221 tcgtcggtct acgcttgtga tgaccagtgc gaactcctcc gatgatccga tcgtgtatcg
     5281 cgacgaagag gcgctccgac tgcttgagca cgtcgccgac ggtgcgctgc tccatgatcg
     5341 ggacatccac atgcggtgtg atgactctct cgtccgtgtg caccagggaa gacggcaggt
     5401 gctgcggcgg gcacgggggt acgcgccggc cccgctgaag ctcgccttct cctctccggt
     5461 gccactgctg gcgtacggag cacacaacaa gaacacgttt tgcctggtga agagtgacga
     5521 cgcgtttata agccaccaca ttggggcgct tcgctcgcct gggaccctga agtcgctccg
     5581 cgagaccgtg cagcactacc agcagttgtt cggtgtcacg cctcaggtcg cagtccacga
     5641 ttaccacccc caataccaat ccacgcgact cgcgttgcag tcggatgtcc ctgtcaaaat
     5701 gagcgttcag catcatgagg cgcacatcgc aagcgttatc gcggagcacg gcattgacgg
     5761 acccgtcatc ggggtcgctg cggatggtgc cggctacggt ccggacggaa ccatctgggg
     5821 cggagagttc ctgatcggtg atctgacgag cttttcacgc ttcgcctact tggagcctgt
     5881 ttcgctccct ggcggggaca gctcggtcaa acgcccttgg atgctggggg tcgtgcacat
     5941 ggagaatgct ttcgggacgg aattcgcggc cctgcccgtg cagttcacca agagcctgga
     6001 cacggcatca ctggagcgcc tcggtcgagt ggctcacgac cccaggctgt ctcccaggac
     6061 atcaagcatg ggacggctct tcgacgcagt gtctgcgatt ctgggactgt ccagtgagat
     6121 ccactatgag gggcaggccg cgatactcct ggaggagcag gcttggcggt tccggaacgg
     6181 cacccgaggc gggcgcatgt cggccccggt caaaccgttc gcggtcgagg tgaatgcctc
     6241 cggcggcccc atccaactgg ggccgctgat ccgcgacctt gtggacgatc tagtggatgg
     6301 ccgcccagaa gaggaagtgg cgtttaggtt tcatctttcg gttgcggaac ttattgtggc
     6361 ggcctgtgaa gccgcgcgac ggcagagcgg aatacagcaa gtcgcgctta gcggaggagt
     6421 ttttcagaac actctcctgc ttgacatggt cgccaacggc ctacagaggc actcattctc
     6481 cgttttcacg aacgaaaaag tccccccgaa tgacggcggg ttgagtcttg ggcaggccgc
     6541 gatcgccgct agtcgcctcc gtagcatccg tgctgtgcaa tgacttgatg atatccaggg
     6601 ttggccacgg taactatgta tgaatcaggc ggaccgcttt tgggcggtcc gcagtacggt
     6661 ggttgggcgg agtccgcctc tctgcgggga atgtcaaccc acggatcaca gtctgcccac
     6721 gagcccatgc ggtgtaattg agccggttgc cggaaacggg catgaccgtt tccgaggacg
     6781 acagccgctg caattttggc gatacaactc gacggcatct gattcggggt catcactcgg
     6841 cattcgatcc accgcacgag gttctcaagg ccacgatcag atttgttgat ccgaaacagt
     6901 tgtggttttg attggttgat cactgtgcga gtgaactggt ggggacgcgc ccccttgaag
     6961 ggggctctct tggagtagct cggccattgc ggacctcact cggctcctcc atggccgagc
     7021 atcaccacct ggatgcaggg cacttggcgc cctccatgca ggaagcgttg cggatgcggg
     7081 taatggccgc gctggtgtgg aggggaagcc gcgaggaccg agagtagatg ttccaggtgt
     7141 cgctcacgac agtcgccggc tggtgggcga agttgaaggt gtatgggcgg gcctgatgcg
     7201 cttgccgtcc gcgagcatcg gccccgcgac ctcgggcttg cggaccaggt ctccaagatg
     7261 gccgtcagca ccggtcctca taggggcagt ggctccagat ccgcaggagg gcgtctccgc
     7321 ggagcggccc tgcaacagcg gcagcattgc gatgtcgcac cgcagttcga cggctacctc
     7381 gctcacatcg ccctgcgctg cccgtacggt ctccagcatg ccgcccgggc cggtcaacgc
     7441 gtcggtgacc tggcccagtt caccgagctc actcgacttg gcctggcaag agcgcaagag
     7501 cgacggatcc cttgaagctg acgtggctcc agcctcgggg tttgagtgct gggccggccg
     7561 atcggggtcc accgttgtca gtcagtggcc gagttgaagg tcctcactgc ggaaggctgc
     7621 accgggtcct ggacgctctc tccgcccacc actctcgaag gacccgcgac ggggacgccg
     7681 cgcatacgga ccagatcgag cttcaccccc tgccccgacc ccactcacaa ggggagcctg
     7741 ctggttcttc caacgtcgcc ggcgtcggcc tcacgtcgtt cgcggctatc tcggaggtca
     7801 gcacgtccgc cgcaccctcg aatagaagca cctgagtctg ggatccaata acaggtacac
     7861 cactacatcg actcgtggaa cgaggccgtg aagcccttca cgtagtcagc catcagccat
     7921 gagatcctcg cgaaggtttt gctcgtccag ggccaccgaa gaaaatcgtc aggaaaaagt
     7981 cgaagtaacg gaatcaggtg cacaagatgc tggtgacggc gatcagaacc tctgggtgtt
     8041 cgagaccatt gaactgatga cagatgcgct ttcctctatg ttctgccata gtcgatcgcg
     8101 gtggtcgacc tgaatgtctc gcgatgctcc accgaaagcg ctgattcgca gctgcaagga
     8161 tccgacccaa acttcgggtt gtcgaaatgc gcacttctcg tgcaatccgg ggttctcact
     8221 gaacgaccaa tccgagagga ggtgtaatat gccggagatt gagcaggact tcgaggacgt
     8281 cgacgtctgc gacctttccg aagaggcgct cgacgatatc gtcggtggcg ggctcatcgt
     8341 gcccatgacg agctgctgac gcatgaggtg ccagcagtcc agccagtagg tccagacccg
     8401 ggccgggcat atctgcccgg cccgggtctg gtcggattca gaagcatcgc cttgaaagtg
     8461 ggcgagttcc gcggaccttt ccgtgcatgc ttgattcgag gctagatcag tgacttgtgt
     8521 cctgagtcgt tgatacgtcg gcagtctgca gggtccgagc ccgatgcctg aatccttgga
     8581 gctgactgcc gaggaacggc gggtactgtg cgggtgggtg agttgtggca aggcggcgca
     8641 ggccctggcc gtgtgttcgc ggatctggcg gcctgggggc tcgagccgta ccaggtggag
     8701 acctgggagc tgtcgaccga ccgacagtgc atcgacaagg tccgtgacgt cgtccgggtc
     8761 ctgcctcgac ccggcggaac gcgcgctggt gttggacgtg gacgagaagg tccaggtgca
     8821 ggccgaccgc accgcgccga tcctccccac caccccagcc agccaaccgc aagctccgcc
     8881 gtttcgccca ccgcggcctc gccattacta ccgacgaatg agcggcaggt gggggataga
     8941 ccgagggccc ggctgccgcg tcgggtgggt gccgggttcc accgctccgg actgggctgg
     9001 tgtctcatag gggtcgtaac agtcctgccc aacccaggct gaccagccgc tttcccaccc
     9061 cgagggcagc atcacccgac ttcggacagt ggcacccgac gctcacccga cacgacagcc
     9121 ggcccatcgg cagttctaca aagcgaaagg ggccgccgac tccgtcgacg gaccctcgtg
     9181 aaagaccgag ctcaaatgta aatcctgact gcccgttgag acgtcctggg gtcgttgact
     9241 gcccgcgttg agacgtccta gggtctcagt cgatcaagca tgcagatcga gatcatccgg
     9301 gaggacaaac gcgacgaact cttcggcggc acggttgccg tttcgctgat ctcggagatc
     9361 ggctcctgat ctgatcactc cgggcgcagc caaaagtact gcgcaaaaca ctctgtgcct
     9421 ccggatggat agcctccgag gacacggagt ggcgacctga aacattctgt tttgaacgcc
     9481 attgccgcag aggaagtctc tcaatgcacg agcggatccc tggcggcggt ggtgtcgggc
     9541 ccactgtttg gaccgcgggc gcgccccgag actgcgctcg atttccttct tcgcagagtg
     9601 gaggtcgaca cggagaggtg attcggctcg atgtgaagaa gctgctcgag gtcaggccgt
     9661 gcagaattcc gctgaacggt tcctgccgtg gagttaggcc gtaacctcac cgccccttac
     9721 ctggtttccg gacaggcgaa caaggcgagc gagcacgtgg tcgtgtgctt ctctgcgctc
     9781 atttccttcg gcggcgattt caccatgccg tcttcacagc ttcaattctc tggttagcgt
     9841 taaggtacgt cggtcgcgcg aatttgccgg tgccgagtcg aatgtggcgg cggagccgaa
     9901 gtcggcgcag ctcggccgac actttttagg gataaaacgt ccgttggaaa cgcgtgctgc
     9961 tgatacgtgt gggagtatgg cacggcccga ggggaaacag gtgctcgaaa gcaagcggaa
    10021 gaaattttct acagccctga ttaccggtgg cgcggggttc atcggtggtc atctggcccg
    10081 tgcgctgcgg caggacggaa cgaccgtccg atccgtggac gacctgcggg tcgcaccgct
    10141 catcaaacct gacggtaacc ttttgataaa gcgagtatcg gatctcaccg ttgatgatgt
    10201 cgagggcgtg gacgtcgtgt accacctcgc ctctgacaag agcgttccgc tctccttcga
    10261 ggcaccgttg cagtacttgg agaatcttga gtccaccgag catttgctgc ggctgtgcgc
    10321 agtggtcgat gttccgcgag tgatcatcgc gagcacatgc gaggtctacg gccgcgcgcg
    10381 tacccggccg acgccggaga acgagccgct ggcgcccttg tcgccctatg cggcgtccaa
    10441 ggtcgccatg gagatggtcg ccagggtcca tcggcactcc gccccccttc ggaaccgggt
    10501 gtcagtggtg cgcttcttca acgtcttcgg tcctggagag cggcctgacg cggtgatccc
    10561 gcgcttctgt ctgggagcgt tgactgatgg cttgcttccg gttgaggggg cgggcactca
    10621 acggcgtgac ttctccttca tcgatgacgt cgtcgacgta ctgcgacgga tgccgatggc
    10681 cgagccggtg ccagtgatca acatcgggtc ggggttcacc gtttctgtcc tggaaatcgc
    10741 tgaggccatc aagggctttt gcccgcgagc tgaggtgaaa cacgtcggtg gccggcagga
    10801 ggagattccg gaattttggg cggatacggc agcgcagcgc actctcgtgg ccaggcccgc
    10861 tgtgcacgcc gacgtccgtg aagggatccg gaagacactg gactggtggg catcgacgag
    10921 tctcgtgcag aatacggtgg caggtggctg ggatggcgag gatcagcctc tactgatttg
    10981 acgggtgcca cccttgcggc ggatcggaag taattttcgt gtcattactg agaaatagct
    11041 acgatataat ttctgtgctg cggaatgcga gcagatggag cattgcgggt attcttgctt
    11101 cttttttcct gctcgccgtg ctgccacccg tctcagcttt gatcacgggc ggcctggtgc
    11161 agtctgtgat cgaggcagag agcggtggtt ctcatggcga ggtctgggtc atgctctccg
    11221 cattcgccgt cgtcacggtg gctgggtggt gtatcagcac gcttatttct cctctgacgt
    11281 ccttggcgac ccgtcaggcc gagggcttcg tgcacgacag actctttgcc ctgggggagc
    11341 agtcgcgcct gttcccgcac ctggagacgt cggccttcgc cgacgacgtt tcccgggtgg
    11401 tggacagtac cgacggtccc aaccgctgcc tcggactcgg cgcggtgaca cagattgaga
    11461 acctatccaa actgctcggc gcgatctgcc tcggcctggt cattgcacgc gtctcggtgc
    11521 tcctcgcgct cttgttgatc gttacggtct tcgccatcag gcacagtctg gtcaagggcc
    11581 tgagcatcgg cctgacccgg atggacgagc aggtcagggc ccgacgtcgt ggtcagtacc
    11641 tttacgacct ggtgagcacg gccgcatcgg ggaaggaggt tcgcaccttc ggcctgggca
    11701 cctggctggt ggaccgcttc cgcaaggaga tgcacgatta tcaccagtcg atcttcttgc
    11761 tgcggcgggg tctggcgcgc cgtgagggcc gtctcctccc ggttctcatg gtggtgtccg
    11821 gagcagcctt cctctggccg gccgtggccg cactgcacgg ccgggtgagc gtcaacgtga
    11881 tgacctcggt cgtcatggcg tgcctctccc tcttcaccac gctccaggcg ggtcaggaac
    11941 agatgtacat cacccccgcg cgactggccc tgcgcgctct cggacgcatc gaagcggtag
    12001 cggacgaggt ccggcgatcg atgtctgaga cggtccctgc cccgtcggac ggcgctccgc
    12061 tgatccgttt ctccggagtc cgcttcggtt acaacaggag ggtccccgtc ctcaacgggc
    12121 tcgacctgga ggtcaagccg ggcgaggtgc tggccatcgt cggtgtgaac ggcgtcggca
    12181 agacgactct cacgaagctt ctggccgggc tctaccaacc cgaagagggc cggatcacgg
    12241 ctgacgggat cgaggtcgga ttgatcgact ccgagcagtg gcacgcccat ctggctgtgg
    12301 tcttccagga cttcgtcaag tacccgctct ccgcgcgcga gaatatcgtg cttgccgcgc
    12361 ctgctcttgc cggggatgaa gaactgatcc gtcgggtggt cgaggaagcg ggcgtctccg
    12421 cactgctcgc cgctctgcct aatggcctgg acacgccttt gtcctcggaa cgcaccggag
    12481 gggtcgatct gtccggtggt cagtggcaga aaatcgccat tgcccgggcg ctgttcgccg
    12541 tccgtgcagg tgcccgtgtg ctgatcctcg acgaacccac ggcgcatctg gacatccgcg
    12601 cggaggccgc cttcttctcc gaggtcgttg gtcgtatcag cggcgtttcc acgatcttga
    12661 tcagccatcg tctgtccacg gtgcgtcagg cggatcgcat cgttctgctc gaccagggac
    12721 gcgtcgccga gtcgggcacc cacgaccaac tgctggccct gaacggccag tacagcgaga
    12781 tgttccattt gcaggctgct cgcttcaagg aaatgaacac cgcggacggt gcagcgtgat
    12841 cagaacaagg ggcagagacg cagagtccgg cggcctgaag cagtcgttgt cgcgatctct
    12901 tgaggtgttc ggaagttcgt tgaggctcgc tttccgggcg aaccggaagg ccgctgtcgc
    12961 cctgttgatc atcatggcgg tcaacgcggt gggcacatcg gcgatcggtc ttgccctcga
    13021 acgcctggtc aacagcgtca ccaaagggac cctgtccggt gtgatcctcg cggcggccct
    13081 cggcgcgctg tgcctggcgc tgctggaggt cggcttccgg gtgcagttca gcctcaggct
    13141 ggaggtctcg gctcgggtca acgttctggt gcaggaagag atcgccactg cagcggccac
    13201 gctcactaca ctcgaacacc tggaggaccc ggcctacttg gaccggatca ccgtcctcag
    13261 gcaggactcg gagtggctgg cagacttctg ttggacgctc ttggagaccg ttgccatcat
    13321 cgtccagatc tcggtcgcgg tggcattgct ggcgcttgtc tccccaccgc tcaccgcact
    13381 gctcgtcctg gccttcccac cggttctgct cacgcgccgt gctcagcgga ttgcgcagcg
    13441 ggcggcggag gacgcggcgg aggacgcgcg gctctccgcg cgcctgctca ccatgagcac
    13501 gcgttctgac tcgctcaagg agatctgcgt caacaacgcg gcgccggctc tgcgcgccaa
    13561 ggccgcccag gcgtggggtt catcgacccg cacccgtgca cgtggcgaat tccggtccgc
    13621 ggcgctgaac ctgtgcggat tcctcatctt caccgtgggc tttctcggcg cgctggccta
    13681 tgccgtcgca gaagcactgt cggggcacgg cacggccggc ggagtcatcc tcgtgatcac
    13741 cctggcaggg cgtctgcaag cgcaggtcgg gcacggcgtc tggctgatcg gccggctgac
    13801 gaaatccatg cttgtcgccg atcgttacgt atggctccgg cagcggctgg ccgcggacac
    13861 ccgcgccggc ctcccggcac caaggaagat cgagcgcggt gtcgtactgg acggtgtgag
    13921 tttccgttac accggcggca ccgaggacgt actacgcgat gtgaacctag agatccccgc
    13981 cggctccgtc gtcgctgtcg tcggcgagaa cggcgctggc aagacgacgc tcgtcaagct
    14041 gctgagtaag ttctactcgc caaccgccgg atccatacgc ttcgacgacg tggacctgac
    14101 cgacatcgac acggtcgact ggcgccggag tatgagcgcg gcctaccagg attacgctcg
    14161 gctggagttt ctcatacggg agagcgtcgg actgggcgaa atcggcagca tcaacgacga
    14221 cggggcgatc caccgggcgt tgcgcaaggc cgattccgac gagtgggtct ccgaactgga
    14281 gcacggtctc aacacccgtc tcggaacgac cttcgatggg gttgatctgt ccctcgggca
    14341 atggcagcga ttggcgttgg cccgctcttc catgcgttct ggcccgttgc tcctcgtcct
    14401 ggacgagccg accgcctcac tggacgcgag gaccgaacac gaccagtacg agaggttcgc
    14461 ggccctggcg aaggaggtgg ggcaggcgac cggcgctgtg actctgctgg tgtcccaccg
    14521 gttctccact gtccagacgg cggacctgat cgcggtggtc aagggcggtg agattgccga
    14581 gttcggcagc caccacgagt tgatggaagc gaacgggttc tacagcgaga tgtaccgcgt
    14641 acaggcgcag gcctattcgt gacggcttgg cagggacacg gaagcgcgta cgggggcggg
    14701 atggacttct ttgatctgca tcactcggac gacgtggcgt tggtgaacgg tgacggtccg
    14761 catcgcacgt gccgtgagcc gatccgtatg tccgatcggg ccggtcggat ggttcggttc
    14821 cgttgctgac ccggacgagc acgctgatct ggggtggcga ttccgtccag gcgctatcgt
    14881 cgcgccgccg gcacagttgc gggacctggg atgtgatgac tcctaccgcg aggtcggacc
    14941 ggccttacct ggaattgaac gggaaaatca attaccgcac tgcttgctga ggcggtggcg
    15001 gtgcgggatg ccaagaaggc ggatattaga tggaactgtg gtgtcagcca ccggagatgg
    15061 acgatctcct gcgggccgtt ggggatcatg cggagatcac tggattccgt gcgatgtccg
    15121 gcgcctcagg ctcgcgcccg ctcatcgtca tgaccaccac cgggtttctc ggaggcccgg
    15181 aactgcggcg tcactgccat gagcaaggaa cagtggcgga tttcgacacc ctcaccgttg
    15241 acgacgtcgt gctggacctg ctgtccccgg acgaactgag caagttggtc acgaactcct
    15301 cggaaggcgc gttctccagg ttcgtcacac ctgagggcga cttggagacc cagttggtca
    15361 ccatgtggga atctctcctg gacttcaccc cgattggtgt cctggacgac ttcgtcgaac
    15421 tcgggggtga atcgatgtcc gcgctggaga tcgtcgtcca ggtgtcccag aggtggggcc
    15481 gggacctgaa cctcgtcgac gtggtcgacg ctgcttgtat tcgcaatctg gcgcgtctca
    15541 tcaccgcgtc gcccgccaac gccgatgaga cctgactcaa tgtcaggcga cacggccccc
    15601 agcgaccgga ttccggctgt ggatatgcct cccggccgct cggaccttgc tccggagctg
    15661 cgggggatgt gcaatttccg cgacttgggc ggtcttcgcc ggaccgatgg gaccagactg
    15721 ccctccggtt ggctcttccg ctcggacgcg ccgaccgcgg actcggccgc cgacctcgac
    15781 cggatacggg ctctcggaat ccgcacgatc gtcgacctga ggtctgcaga ggagcagccg
    15841 tcgtgcccgc cggccctcag atcaacctgc gcctatgtgt ctatgccgat cgacagggtc
    15901 gaatgggcgg actccgccct ggcatccgag gatatggctg acttcctcgc aggacgatat
    15961 ctgcgtctcg ctgcacagtg tctgacggac gacgatcggc atctgggtag cgcgctgaac
    16021 gtccttgggc ttccctgtga ccagccgcgg attgtctggt gcgctggggg aaaggaccgc
    16081 acgggccttg tcacggcgat ccttctgcgt ctgctcggcg ttaccgacga cgacattcgc
    16141 gcggactacg cgcgcagttc ctttgctgcg gccgaacttc gccgacgcgc aagggttgag
    16201 actcccgcga aggccggccg agccgtttcg cctgaggagc ggcgcgccgc cctgcgcggg
    16261 cgactcgcct cgttctccga aggaatcggc cgcctgtcga acccggcgcc ccccgaagcg
    16321 atagggctgt tcctggcgag tctgtccgca cgtcgtggcg gagtggagtc ctacgcggcc
    16381 tccgtgggcg ccgacatgga gacaatcgct atgacacgac gatggttgtc agctctcgct
    16441 gtggccccct gacgccgtct acccgacctt gcttcgagag ggaatacgac cagatgaaga
    16501 tcctcatctc ggtgtctgac caggtgtggg gtcgcaaaga ccagtacgtg atcgacgcca
    16561 tcatcgggtt gctggcctac ggacacgcgg tctgcccggc tgtcgaggaa ggaggcacga
    16621 tggcagcgga actgacgcgg cgcgtcatat cgcaaatgag ggtctccgcg ttctgtgcca
    16681 atccccgtga ggcggccgag gccgacgtgc gctggcgtga cgaaaccgga agcggctttg
    16741 tcttcgtccc ggtgaactcc ccgaacaccg aactccccgc gactaaccac ctcctggtca
    16801 aggcagtcct gacggcacaa cgtgcggaag atccgctcaa actgtcggcc gggcgtgacc
    16861 gggatctggt caacctcttc tacgccgtgg gtgctctagt tcccaaccgc ccgaaggcga
    16921 tgtgctgatg cgcgtcttgg tgacaggagg ggccggatac gtcggctcgt tcgtggtgcg
    16981 gcacttgctg gagcgcaacc atgacgtgcg ggtgctggac gacctcagca cagggcgggc
    17041 cgaggctgtg cccgatatcg ctcccgacat cgtgaacatc cgccacgctc aagacgtcgc
    17101 agccgtcgtc cggtccttcg cacccgaagc catcatccac ttggccgggc tgaaatcctc
    17161 cgccgaatcg gtgcagcgtc ccgatctcta ctacgacgta aacgtcacgg gtacgtccgc
    17221 tctactgcga gccgccaaac gccacggggt cgagcgcttc gtgttctcgt cgtcctgcgc
    17281 ggtgtacggt agcccgcagg tctgtccggt ggacgagcac gcccccaccg agccgcagag
    17341 cccctacggt gagaccaagc ttgcctgtga gcggatgctg cagtggcatg ccagggtgac
    17401 cggcatgagg tgggccgcgc tgaggtactt caatgtggcg ggggccgcag cggacggctc
    17461 gctgggcgag ttcaccgggc cacataccgt ccaactcgtc cccttggcca tcaaagcggc
    17521 cagaagcggt gtaccgctca agatctacgg tggagactac ccgaccttcg acggtacggc
    17581 cgtccgcgac tacctgcatg tcgttgatct ggccgaggca catgtgcgcc tgatcgaggg
    17641 cctcgagaca cctgaactca gcggagtcta caacctgggt accggccggc cggcgagcgt
    17701 cctggagatc gtgaagatga tcgagcaggt ctccggctgc cccgtgccgt atcatttggc
    17761 cccgcgccgc aacggtgatc cggcgttctc atgggcggat tcggaacacg cccgccggac
    17821 cttcgactgg gttccacagc ggaagctcga cgagatcgta cgctccgcct ggctgtggca
    17881 ctcctccgga cggtcgggcg aggcctgatg gacctcttgc tgatcaggca cgctcacgac
    17941 gaccgggtcg gaccgcacgc tcggcggttg tcggcactgg gccgcgcaca gtgtgccgcc
    18001 ctggccaaaa cgctgatcgg atcacgcgtg gacgagttgt ggacctcgcc ccgctcccgt
    18061 gcggtcgaga ccgcccgcga gatctccagg acactacgac tgccgctgcg gacagacccg
    18121 cgcatcgagg agataaggac cgcgcggcca gaagatccgg acgtactacc gccgcgcgaa
    18181 cgcgtcggcg tgaccctcgc cgacgggacg gaggattgga acgccttcct cgatcgcgta
    18241 tccgcgttcg tgagtgaacg gtgtctcggt tcgcatgatg accgcacggt cgcggtggtg
    18301 acgcacagtg gtgtcttcga cgcggtccac gaagtcctca ccggcagtgg gcgacgtatc
    18361 gagctggaga tcgcgcacac cggcttcacc acgtggcgtc accggcccgg ctcgtccgcg
    18421 ggcacctggc tcctgcgccg ccacaacgac gtggcccacc ttgcccgcga ggggcttctc
    18481 accgatgccg accaagtcga acggagaccg tgatgagcca gtaccgaggg ccgcgactgg
    18541 tcgtgctctg cgtggacggg gggttgccca gtgtcgtggg gacgtggaac tttttctccc
    18601 cgcaccgtcg tttgccggac tcgcacgaca gcggagccac ggccctgcgc tcggttttcc
    18661 cctcctcgac cgcgccggcc cacgcctcgt tcctgaccgg tgcgcacccc acagagcacg
    18721 gagtgatcgg taaccggtac tggacgggtg agccggtggc ggaaatctgc cgtcgcgccg
    18781 ccaacccctt gctgaccctg cacccctacg acgctgcttc cctcaccgcc ccctccctcg
    18841 tggagtggct cgcggaccag ggggcgaggg tcgcggcggt gcacttcccg cagactttct
    18901 cccagattgc gcccagccgc gccgtctcca gtctctattg cctttacgca ccggcgaggc
    18961 gggtcctcgt gcccctggcg gacggcacgg accgggagac cgtgcaggcg gtctacttcg
    19021 acgagagtct cccgctcacc gcccgcgtcc cgtcgggcgg tggggcgcag accgtgatgt
    19081 tctccattgg gaccgcagga cccgaaaccg ccgtaccggt cgcgggccgg accgtccagg
    19141 tcgacgcgag gatcacggaa gggaacctct ctgtcccggt cagatgcgag aaggtggcac
    19201 acggaacggc cgagctcgtg ctcgggacgg cggttctcac actctccttc ggtgctgtcg
    19261 ccgctcgtga cttgcgcttc ccgggctgcg gaggaccaag ctcactcgga atcgagtaca
    19321 cggccaaccc ggaacacgat ttccacgagt cgccgagcgc gccgtggatt cgcgattccg
    19381 cgcttgacat cgtggcaaag gacgagccgg acgtcctgtt cctgcggttc aaccaggccg
    19441 accatgccca ggagttcctc tactggtacg cggcgcgctc cggcggtcgc gaggcagccc
    19501 tcgcccgcga acagatcctg agcagctatc agaccatcga cgcctgcgtc ggcgacatca
    19561 tgcgtgaagt gggcgaccag gccgactacg tgctgttctc cgaccacgga atcgactacg
    19621 tcgagaccca cctccagccc aacgtcgtgc tgcgcgaact cggccttgac acagggatga
    19681 tcttccaggg cgacagcaac atcgcctacc tctacgccga ccgacccgtg tcccagactg
    19741 atcgcaggcg tatcatcaac gccttggccg cagtcgatac gaccgtgcgg cccgctgacg
    19801 ccgtatccca tgccgtacga ctgccgtcgg ctcccggcag gacgggagaa ctcctcatca
    19861 cctgtggtcc gcacagggag ttcgactacg ggttctcggg gcccgccggg gtagcagttc
    19921 gctccgcctc acacggctat ttcccctcgt acccggcgat gaacggcttc ttccgcatgt
    19981 ttgggccccg aacagcgggt catgaagcgc cgggagcaat taccgacgtg gccgatctcg
    20041 tcaagaacct ctggttgcga ggccaatagg ccctcacagc cggccgagct gacactactc
    20101 acgaattcct tactgacacc acgggacact cacatgagct cactttcgac acctcttctc
    20161 ttcgctgggg gaggaagcag gccgcatgca cttcccgttg gcctgtccga cctgggtgag
    20221 ttcaagcttc ccgaacaggc gctgctcagc ccggacggcg agctcgttgc cgtcaccgtg
    20281 cggtgggtgg acgaggacca tgaccggtgg acgacccgtc tcgaagtcgt ctccagcacg
    20341 gggcatgccg gtgccggggg tccgctggcg gttatcgagg gagccgacgc gccgtgctgg
    20401 tcgccggacg gcacccgact cggctacctg gcccggaacg aaggctcaga ccgctcgggg
    20461 cgggctatcc acgtctggcg gcgtgaagac ggcaccagct ttcggctgac cgaagggatg
    20521 acggcgattt cgcacctgtc ctggtcgccg gatggcgagg agttggcctt cgtggcagcc
    20581 cttcccgaag aggccgcccg gtctccccgc ggaggtgagc ggccatatcg acggaccgat
    20641 cctgtcgtgg tccgggactt cggatacaag atggacggcg tcggcctcgt cccggaggtt
    20701 caccgccacc tggccgtcgt gagcgcgacc acaggaaccg tgaggaggct gacctccggc
    20761 gcattcgacg tccaggctcc ctcctggtcg ccaagcggcc ggaccctggt tcacgccaga
    20821 atccatcggc accgccacgg gccgacggcg gtatgcgagt tggccgaggt tgacacgacc
    20881 tctctgtcga gccggaagct cgccgactgg aagggcacca tcgcctggac cggccacata
    20941 cccggcggcg acgtcatctt cgccgggcag acgggcgtgg g
//
