LOCUS       NZ_SHKU01000001        22168 bp    DNA     linear   CON 27-MAY-2024
DEFINITION  Streptomyces sp. BK022 Ga0307664_101, whole genome shotgun sequence.
ACCESSION   NZ_SHKU01000001
VERSION     NZ_SHKU01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. BK022
  ORGANISM  Streptomyces sp. BK022
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 1305487)
  AUTHORS   Kalluri,U.
  TITLE     Understanding the reciprocal impacts of modified plant cell wall and
            associated microbiome
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1305487)
  AUTHORS   Kalluri,U., Huntemann,M., Clum,A., Pillay,M., Palaniappan,K.,
            Varghese,N., Mikhailova,N., Stamatis,D., Reddy,T., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-FEB-2019) Prokaryotic Super Group, DOE Joint Genome
            Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.12.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 215.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004217355.1-RS_2024_05_27
            Annotation Date                   :: 05/27/2024 02:58:00
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,482
            CDSs (total)                      :: 6,401
            Genes (coding)                    :: 6,280
            CDSs (with protein)               :: 6,280
            Genes (RNA)                       :: 81
            rRNAs                             :: 5, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 16S)
            partial rRNAs                     :: 3, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 121
            CDSs (without protein)            :: 121
            Pseudo Genes (ambiguous residues) :: 0 of 121
            Pseudo Genes (frameshifted)       :: 49 of 121
            Pseudo Genes (incomplete)         :: 92 of 121
            Pseudo Genes (internal stop)      :: 16 of 121
            Pseudo Genes (multiple problems)  :: 29 of 121
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:05:10
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 172526
            Orig. end                         :: 194694
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            SHKU01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22168
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="2"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..22168
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22168
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12168](-)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12168)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     gene            169..942
                     /locus_tag="EV284_RS00805"
                     /old_locus_tag="EV284_0164"
     CDS             169..942
                     /EC_number="1.3.1.106"
                     /GO_function="GO:0016994 - precorrin-6A reductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019070853.1"
                     /locus_tag="EV284_RS00805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_0164"
                     /product="cobalt-precorrin-6A reductase"
                     /protein_id="WP_130329244.1"
                     /transl_table=11
                     /translation="MPAHVLILGGTTESRRLATALAARPGLRVTSSLAGRVSRPGAVDG
                     EVRVGGFGGAAGLADWLRAHRVTALVDATHPFAERITANAAEAARAAGVPHAVLRRLGW
                     NLDDDWFPVASLEEAARLLPRLGRRVFLSTGRLGLAAFAHVTAVQFVVRSVEPPEPPLP
                     PQCELVLAKGPFSLSDELGLLRAHRIDVLVTKDSGGAATAPKLAAARSLSLPVVVVRRP
                     ELPFGVRTLPDVEDVLGWLAGVIPPEGACAADTCP"
     gene            complement(899..1672)
                     /gene="cobF"
                     /locus_tag="EV284_RS00810"
                     /old_locus_tag="EV284_0165"
     CDS             complement(899..1672)
                     /EC_number="2.1.1.152"
                     /GO_function="GO:0043819 - precorrin-6A synthase
                     (deacetylating) activity [Evidence IEA]"
                     /GO_process="GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cobF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TP_methylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020129516.1"
                     /locus_tag="EV284_RS00810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_0165"
                     /product="precorrin-6A synthase (deacetylating)"
                     /protein_id="WP_130329246.1"
                     /sec_met_domain="TP_methylase (E-value: 1.4e-28, bitscore:
                     96.5, seeds: 87, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKIHVIGIGAGDPDQLTLQAVKAMRGTDVFFLLDKGEVKSDLTR
                     LRQDILDAHLPEGSYRVVAARDPERDRKAGGAAYSPAVGDWRTARAGIYERLIAEEVTE
                     DGTGAFLVWGDPSLYDSTLGILQEVLAGGAVQFTYDVVPGISSVSALVARHRTGLNRVA
                     RPVQITTGRRLAEGLPEGVDDVVVMLDAHQAFREYTGEDIDIYWGAYIGTPDEILVSGP
                     LAEAGPEIERVRAEARERKGWIMDTYLLRRHPRGE"
     gene            1814..2389
                     /locus_tag="EV284_RS00815"
                     /old_locus_tag="EV284_0166"
     CDS             1814..2389
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010351208.1"
                     /locus_tag="EV284_RS00815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_0166"
                     /product="ALF repeat-containing protein"
                     /protein_id="WP_130329248.1"
                     /transl_table=11
                     /translation="MTRTTRAALLLAATALTPALLLSTPASAAVAATTASVTASTPVDQ
                     MSDDDVRVAISRILADPASGEAVLREANEALDGTIADQRAFLETGYRLAQAEDDRVAIT
                     RILADPTSGKAVIREASKALDGTMDDQRAFLETGYRLAQGEDDRVAALRILADPKSSPA
                     LRAAASAALDGTLEELRYFIAVGQYQVH"
     gene            2484..3365
                     /locus_tag="EV284_RS00820"
                     /old_locus_tag="EV284_0167"
     CDS             2484..3365
                     /NRPS_PKS="Domain: PKS_KR (9-180). E-value: 1.8e-17. Score:
                     55.8. Matches aSDomain:
                     nrpspksdomains_EV284_RS00820_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020120217.1"
                     /locus_tag="EV284_RS00820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_0167"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_130329249.1"
                     /sec_met_domain="adh_short (E-value: 5.5e-33, bitscore:
                     110.6, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYDSPLAGRTVVVTGAARGLGAALAHAFAERGARLALLGLEGPRL
                     EGVAASLPPPVIAVEVDITDFGALERAAAEVRERLGRPSVVVANAGIAEGGPFAGSTPE
                     SWRRVIDVNLVGSALTARAFLADLLVTSGYFLQVASLAAFGTSPMMSAYCASKAGVESF
                     ARSLQAEVAHESVGVGIAYINWTDTDMTRDADHYPVLRELRAHMPAPARRVYPAEVVAE
                     RLVSAVEHRRTSVYVPAWLRLAQWGRAVLPPVVRHVSRRTLPRLQAERALPPTGLLGAG
                     GAADEERREGRA"
     CDS_motif       2511..2600
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EV284_RS00820_0001"
                     /evalue="7.50E-07"
                     /label="PKSI-KR_m1"
                     /locus_tag="EV284_RS00820"
                     /protein_end="39"
                     /protein_start="9"
                     /score="21.8"
                     /tool="antismash"
                     /translation="TVVVTGAARGLGAALAHAFAERGARLALLG"
     aSDomain        2511..3023
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EV284_RS00820_PKS_KR.1"
                     /evalue="1.80E-17"
                     /label="EV284_RS00820_PKS_KR.1"
                     /locus_tag="EV284_RS00820"
                     /protein_end="180"
                     /protein_start="9"
                     /score="55.8"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TVVVTGAARGLGAALAHAFAERGARLALLGLEGPRLEGVAASLPP
                     PVIAVEVDITDFGALERAAAEVRERLGRPSVVVANAGIAEGGPFAGSTPESWRRVIDVN
                     LVGSALTARAFLADLLVTSGYFLQVASLAAFGTSPMMSAYCASKAGVESFARSLQAEVA
                     HESVGVGI"
     gene            complement(3427..4602)
                     /locus_tag="EV284_RS00825"
                     /old_locus_tag="EV284_0168"
     CDS             complement(3427..4602)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009718845.1"
                     /locus_tag="EV284_RS00825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_0168"
                     /product="glutathione-independent formaldehyde
                     dehydrogenase"
                     /protein_id="WP_130329251.1"
                     /sec_met_domain="ADH_N (E-value: 1.6e-28, bitscore: 94.9,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.1e-11, bitscore:
                     41.0, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAAVYEGPRTVAVKDVPDAKIEHPCDIIVKITTTNICGSDLHMY
                     EGRTSFEPGRTFGHENMGQVVEVGPAVRKVQVGEYVVLPFNIACGFCKQCERGLTNYCL
                     TMQPEPALAGAAYGFADMGPYQGGQAELLRVPYGDFNALRLGEDAAERQTDYVMLADIF
                     PTGYHATEMAHVKPGDQTIVFGAGPVGLMAAYSALLKGAGRVWVVDHQPDRLHKAEEIG
                     AIPVNTAEQDPAEVVKDATLGLGADNGCECVGYQAHDAQGHEDASLTLNGLIDSVRFTG
                     DIGVVGVFLPEDPGGEQAQNELEAHGKVPIDFGMMWFKGQHVGTGQAPVKRYNRALRDL
                     IAGGKAKPSFVVSHELGLDQAPTGYEHFDARDDGWTKVVLHPDGRGNGHRG"
     gene            complement(4829..5962)
                     /locus_tag="EV284_RS00830"
                     /old_locus_tag="EV284_0169"
     CDS             complement(4829..5962)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007387047.1"
                     /locus_tag="EV284_RS00830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_0169"
                     /product="hypothetical protein"
                     /protein_id="WP_242625591.1"
                     /transl_table=11
                     /translation="MVSSEDVTVVALLADPDAPTEIARRLARTLPDPLAKKAGDGRRFE
                     FRVVSEPFTAGTEDPPTLVRRIMDRARTEDWDIVVAITDLPLHVHGRKLVVELSHEHGL
                     ALLSLPTLGGLRLQTRAARAVEQVVLTLAAPQTPGTDGHPQSRPLGHFVSRFAPIHPGP
                     VDEDEAADLRYVVGGPRGYLRVLVGMVRANRPWRLVPGLSKALAAALATGAVATVNSTV
                     WSLSQALSTPRLVISTVGSVAIMIGWLIVDAQLWHRPANALPEEKRRTSLYNTSTVLTV
                     GIGVIVCYVGLLAVSLVWALFILNDKVFATTTQNQLHTTDYWTLAWFVASVATVGGALG
                     SGLESDEAIRAAAFSKREQERRDMLQEDDDDRDRSET"
     gene            complement(6123..6638)
                     /locus_tag="EV284_RS00835"
                     /old_locus_tag="EV284_0170"
     CDS             complement(6123..6638)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009302785.1"
                     /locus_tag="EV284_RS00835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_0170"
                     /product="DUF309 domain-containing protein"
                     /protein_id="WP_130329255.1"
                     /transl_table=11
                     /translation="MTDAETGGDSGGRDRDTDGRARNARPRDGLGRPLPYGSAGVERQP
                     EGVVRSPDETVAEAQALLDEGKPFHAHEVFEDAWKSGPDTERELWRGLAQIAVGLTHSA
                     RGNITGGPRLLRRGAAAVTAWSGQNQPHPYDLDLPGLATWAVDLAGRVEAASAPVDAGA
                     EGPRLRRG"
     tRNA            6745..6818
                     /anticodon=(pos:179305..179307,aa:Pro,seq:ggg)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="EV284_RS00840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="EV284_0171"
                     /product="tRNA-Pro"
     gene            6745..6818
                     /locus_tag="EV284_RS00840"
                     /old_locus_tag="EV284_0171"
     misc_feature    complement(6908..6921)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.18"
                     /tool="antismash"
     gene            complement(7006..7641)
                     /locus_tag="EV284_RS00845"
                     /old_locus_tag="EV284_0172"
     CDS             complement(7006..7641)
                     /EC_number="1.14.11.-"
                     /GO_function="GO:0008198 - ferrous iron binding [Evidence
                     IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025024.4"
                     /locus_tag="EV284_RS00845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_0172"
                     /product="2OG-Fe(II) oxygenase"
                     /protein_id="WP_130329257.1"
                     /transl_table=11
                     /translation="MPNPATPLTDTMKIDVRTAPFPHLTVTDLFGSEDAEAVLGWLERF
                     DGWTSKSEQHYKSDVHHFAADSLPEDLAAVLTEDKLSRVRELMESSFKVRFRPDHFLLA
                     NRYVPGDGTAVHSDFNPDTGHKYFFTHRLIAYFNRSWEEADGGILGLFDSQESTSPAVQ
                     YPPLHNTAAGMAMSESSFHAVGALRGGLRYCLIFSFTTEDLQYQRSLR"
     gene            complement(7643..8827)
                     /locus_tag="EV284_RS00850"
                     /old_locus_tag="EV284_0173"
     CDS             complement(7643..8827)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EV284_RS00850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EV284_0173"
                     /product="hypothetical protein"
                     /protein_id="WP_130329259.1"
                     /transl_table=11
                     /translation="MSESPGAAALRAAAHRTAAQLGHDTRRTPGNHVVPMSGTTVEIRL
                     FLPWTRPAWPAAGHTRPVNARLRELLAAPFRHGARVKAVDAIGGLSVSAYVAPERSLAF
                     LTALARLPELMPDMAVPLPPGEPVASGSPDESIEDVARRQALRLLPAGPDRTPAEDHTR
                     PDWGRAHLVVVGPVDHRADIPTWAASHTPSVSPAVNAPDSPSGPHEGRHTHDVSAVGIV
                     CPLSGAPAAEELAATVVGGSHAADLVEILRERLGIAYAPDMVVHRRAGLPHLWTWLPVA
                     PQHFRLLTRTVALATSRPRRCDEDRLDRAKSHLAGKLERALCEPRALANLLVGHPPHGS
                     GPESLRDHYMTVADTSPHEVDAAAERLLARRAVLVMGPDNTSEALENAFSHHGG"
     gene            complement(8820..10004)
                     /locus_tag="EV284_RS00855"
                     /old_locus_tag="EV284_0174"
     CDS             complement(8820..10004)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012879.4"
                     /locus_tag="EV284_RS00855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_0174"
                     /product="insulinase family protein"
                     /protein_id="WP_165425418.1"
                     /sec_met_domain="Peptidase_M16 (E-value: 2.2e-13, bitscore:
                     46.6, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIPAPTAPWGLSVHVERAPGPQFTWASAWPVGFRSEGPGEHGLAH
                     LCEHLLFQGTDAHPKLDYFRRVEAAGGIANARTRPDFTVHFGGARATHWQEILRLEGDR
                     FHGTLASADVIANQQAVVAAEVQEKLLGNPRGTYPWVDVPRALFTDPAHAHDGYAAPAL
                     APAPTPATVAAFYRSAYEQARPVLWLRGPFEEREAVAVVEESFAPPRMEARPGRGAART
                     HRMPSPAVPSHPTGSALAWALSGPSVHKQFTALLVLVEAMNDILAPTLGATAYWGMFDE
                     PCQMSDPWYVTVEAPGSPDRLRTAVRDLLSGLVRTPPAAATVEGWAASRLLTLRRPEAD
                     PVEYTVRRAVDTLLHDDPAFTQARCDELTSVSAADVAEAAALVLEAGWVVLPHE"
     gene            complement(10001..10744)
                     /locus_tag="EV284_RS00860"
                     /old_locus_tag="EV284_0175"
     CDS             complement(10001..10744)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF013077.4"
                     /locus_tag="EV284_RS00860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_0175"
                     /product="SagB/ThcOx family dehydrogenase"
                     /protein_id="WP_130329263.1"
                     /sec_met_domain="PF00881 (E-value: 2e-21, bitscore: 72.9,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTHSFAYPDFHAASSTEGRYMESENWTSVAHWPRAWLDIVFKTY
                     PRMPLLPLPDVPWESQLSLSEALVQRSSDRANVAEPLALDTLSVLLRESTRIKPTAVDH
                     GSRRVYPSAGARFPVEVYVAVSRCEGVASGLYHYRPLDHALEQLAAGPQRDRLRRVFGH
                     DWIADARCVVLLSAELSRSAVKYGDRAYRFSLIEAGHLMHNLLLVGTDLGSAVTPIGGF
                     ADDRMHRYLGLGPTEEYVLYSAVVS"
     gene            complement(10759..12168)
                     /locus_tag="EV284_RS00865"
                     /old_locus_tag="EV284_0176"
     CDS             complement(10759..12168)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF014661.4"
                     /locus_tag="EV284_RS00865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_0176"
                     /product="YcaO-like family protein"
                     /protein_id="WP_130329265.1"
                     /sec_met_domain="YcaO (E-value: 4.4e-50, bitscore: 167.4,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLSAPGWAAPEDTRGTMPGSRHDTAPRLSFDRLVDGGEPDARAL
                     LPRFTTAVSSDVGIVRLLAEERDYYNDEPATLLHRAEVVPTHRLSSSGYTKRAAEGGRG
                     FDAGTTTVGALFEAFERYSLSVYREEHLLRGSHEALTAQGAQAVAPSRFLCARTATENE
                     RRRVDGTERAWVRGTSVATGAVVLVPAQTVFLPYYVSEDEGYLRDPLTTGAAAGLAPAA
                     AARRGLLEAVERDAVMLMHYLNLVPDALDAGAVNDDRLLELLRDARRHHLEIRLFRVPT
                     DLPVHVVVAQVLDRSGVGPEMTVGSKASLSLSDAMVGAVLEAICFRRGLRDRLDHARQY
                     AEQHLHTGFDINCLEERTYYWMQPGRSSRLSYLEDAGAPADPGAFADRAGSMRGLVEEL
                     LDRVGDIVLVDVTTDDVRELGVSVMKAVVPELQPMHLAEPLRIFTRRLLSLGARHGQET
                     PELNDVPHPFL"
     gene            complement(12165..13067)
                     /locus_tag="EV284_RS00870"
                     /old_locus_tag="EV284_0177"
     CDS             complement(12165..13067)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR03882.1"
                     /locus_tag="EV284_RS00870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_0177"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_130329267.1"
                     /transl_table=11
                     /translation="MSTFEIAADAALFDDGKEVVVYRSTTRSGFALRGLWGDLLGVVWH
                     RVIDGGADSGELVALLAERGVDREEATDFLAELTRRGVFTDPAEPAPLSRPLERISVAG
                     LPRAASLLTGLLSEQADGEDPTPEIVDWVPGEVAAPGSRAVVVVADATEIGLFREANRD
                     ALRSGSPFLTAMLGAGTVTLGPTVIPGGSACFECYWTRRTMEDDAATPQWITRSRPRIP
                     GSAGKPGANSTGLHMATALLAREISRLRHGAFGPALVSKVSVLDEATFSGDVHAVFPVP
                     SCRACALTEEVVREGTHSR"
     gene            complement(13064..14392)
                     /locus_tag="EV284_RS00875"
                     /old_locus_tag="EV284_0178"
     CDS             complement(13064..14392)
                     /GO_function="GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015905.4"
                     /locus_tag="EV284_RS00875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_0178"
                     /product="MmgE/PrpD family protein"
                     /protein_id="WP_130329269.1"
                     /transl_table=11
                     /translation="MNWNELPEGVAGAMSRPPAPCHVEEFTFTLVDTLASAWSAQPLPA
                     VPLRPVVREGDQATSWTTGGLLSPSTACYDNAHATHASEFDCIHYMAVGHPGAVLLPAL
                     LALLECGLVTAQQVIRGYLAGLETMVTLGESVGDQLRKRGFHATPVLGAPATAAAVAGS
                     LGLGPPALSTAMFLALTSQSGYACAHGTVGKAHQVAAASRGGLEAGLRAASLRESERVD
                     AWYAPLEALLQEKLSLPVHGFGDPWALDVLPTHYKKYPLCGYFDAPLDHLESLRGNGFL
                     RDALGVTLGVPEYVATASKYQRPRTVEEARFSLPYAVAGLLTRGAVTPALFTEAAVADA
                     VLAHQAYDVTVEEVPGELGPLGDTLPGFVRVRRRDGSEESLTVVYEVVPPTTDWTRARA
                     KLAGSLPRADSATADGIITGLRGFGQLDGPGLGRLLAWGAENR"
     gene            complement(14507..15781)
                     /locus_tag="EV284_RS00880"
                     /old_locus_tag="EV284_0179"
     CDS             complement(14507..15781)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="EV284_RS00880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_0179"
                     /product="MFS transporter"
                     /protein_id="WP_130329271.1"
                     /transl_table=11
                     /translation="MKEHHVTEPSAGGSTPWSRPAVLAVTFATFLSSAAFYLNFPILPL
                     YVAHLGHGHVGAWLGPIVGVTFLVSAIVNPFWGALADRFGQRAMMLRAAAAVTVVYALT
                     PLAVTPSSLFALRVLAGLASGFIPAATALLSRHVPEERLGRTMSLLSVARNAGALLGPA
                     VGTLLTTGDSFVLVYAVAAALMALCFLLALFVPRERGAPGAERPPLWDRHLWLQPLRSL
                     GARGTSGLRPVLAVVLLTSMAAAVVQVLLPLQLAEVGGASGRRLAGLAFSVGGVASLLT
                     AYGWGRLTDRLGTRVLLLGVFTGGAAASVLLFAARTTWTVLAAYALYCVVLCEVFTLLT
                     VALARRESAETRGTVFGLNNTVMQLGQALGPTLAGFAVSFCSPTTGVLLTSLLLGGSLV
                     VTATTSAGDRPRPHTEQPSPEPIKR"
     gene            complement(15864..16091)
                     /locus_tag="EV284_RS00885"
                     /old_locus_tag="EV284_0180"
     CDS             complement(15864..16091)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EV284_RS00885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EV284_0180"
                     /product="hypothetical protein"
                     /protein_id="WP_130329273.1"
                     /transl_table=11
                     /translation="MSFEFAEFGTERTAETAELINASSDNGRALINASSDNGRALINAS
                     SDNGRALINASSDNGRALINASSDNGRTAL"
     misc_feature    16334..16344
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     misc_feature    16397..16412
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     misc_feature    16898..16910
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 20.41"
                     /tool="antismash"
     gene            complement(16907..17575)
                     /locus_tag="EV284_RS00895"
                     /old_locus_tag="EV284_0181"
     CDS             complement(16907..17575)
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011026982.1"
                     /locus_tag="EV284_RS00895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_0181"
                     /product="Type 1 glutamine amidotransferase-like
                     domain-containing protein"
                     /protein_id="WP_130329275.1"
                     /transl_table=11
                     /translation="MNLLLTSAGLRNESLKDALRDMLGRPFGSANLVYVPTASMAESGD
                     HGWLLADMTRVHGLGWREFDILELNGLPRQLVLDRLLRADVIYVGGGNHYHLARSITGN
                     GLADGFLKALADRVYVGLSAGSMILSRHLTEHSADVIGDTADLRLLGASTVTPPFGLLD
                     SYLKPHLYSPDFPERDDAWADRIVARADFPIHFIDDDTAVRVRGDKVDVVSEGRWRFHP
                     "
     gene            complement(17684..18058)
                     /locus_tag="EV284_RS00900"
                     /old_locus_tag="EV284_0182"
     CDS             complement(17684..18058)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018530414.1"
                     /locus_tag="EV284_RS00900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_0182"
                     /product="VOC family protein"
                     /protein_id="WP_130329277.1"
                     /transl_table=11
                     /translation="MTTLLAAFVLGTPDPPALADFYRALLGWDEVDREPDWVRLKAPEH
                     ERPGLSFQLEKDHRAPAWPSGPGEQQMQAHLDIQVDDLAAETERACALGATVEEHQPQN
                     DVRVLRDPHGHLFCLFLPGA"
     misc_feature    complement(18111..18122)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.28"
                     /tool="antismash"
     gene            complement(18127..18414)
                     /locus_tag="EV284_RS00905"
                     /old_locus_tag="EV284_0183"
     CDS             complement(18127..18414)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009192154.1"
                     /locus_tag="EV284_RS00905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_0183"
                     /product="DUF4190 domain-containing protein"
                     /protein_id="WP_130329279.1"
                     /transl_table=11
                     /translation="MTSYGGQPTARSGSRANGLAIAGLVCGIVGFFFLNVVLGPLAIIL
                     GMVATRQPGARGGRGMAKAAVVLGIVDLVVFAILMIVAANTGGFHWYVGN"
     gene            18756..20462
                     /locus_tag="EV284_RS00910"
                     /old_locus_tag="EV284_0184"
     CDS             18756..20462
                     /EC_number="3.6.4.12"
                     /GO_function="GO:0004386 - helicase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1122: ATP-dependent
                     RNA helicase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125998.1"
                     /locus_tag="EV284_RS00910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_0184"
                     /product="RecQ family ATP-dependent DNA helicase"
                     /protein_id="WP_130330929.1"
                     /transl_table=11
                     /translation="MTTASAKRLRKSAADVFGWEELRPEQLLAMEAVMERRDTLVVMPT
                     GAGKSAVYQVPGLLLPGPTVVVSPLVALQRDQVRGLLNREGAEAAAVNSSQSGSENAAV
                     WDRISEGDVDFLFLAPEQLAKDEVVEQLAAAEPALFVVDEAQCVSSWGHDFRPDYLRLG
                     QVIDRLGRPPVLALTASAAAPVRADIVSQLGMRDVREVVTGFDRPNIHLEVIPFQDATA
                     KKRAVVERAAAEAKPGLVYAGTRREAEEYAEELSLLGLDAAAYHAGLPARERGEVHDRF
                     MAGELDVVVATSAFGMGIDKPDVRFVLHASVPGSLDAYYQEIGRAGRDGEKARAILAYR
                     PQDLGMQRFFAAGRPDPDTVTQVVSTLEEHDGPVPPTELREQTNLTSSRLTAVVNLLEQ
                     VDAVHTTEDGELEATGTAGPADAAQQAIELGDAHQQLERSRVDMMRGYAEATGCRRRFL
                     LGYFGQGGEQDESCGACDRCEAAELAEEGGAECGPAVLAGTGGPIPESTSPAPAGDPHP
                     FPPGTLVRHEQWGQGSVMSEENERLTVLFETVGYRTLSLEVINRNQLLTVC"
     gene            complement(20589..21149)
                     /locus_tag="EV284_RS00915"
                     /old_locus_tag="EV284_0186"
     CDS             complement(20589..21149)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019526941.1"
                     /locus_tag="EV284_RS00915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV284_0186"
                     /product="phosphatase PAP2 family protein"
                     /protein_id="WP_130329281.1"
                     /transl_table=11
                     /translation="MADRDIASAVLGDLRAVDGALYAAVAATPTPALDRALRLLSHAAD
                     HSKISFGVAAGLALLPGRPRRAALAGVVSVTLASAAANLLGKRMVRRHRPDREQAQVAV
                     ARHVRMPESASFPSGHTASATAFATAVGVVLPPAAVPLGSLAVAVGYSRVHTGVHYPGD
                     VAAGAVLGFAAAAVSLAVVRKLG"
     misc_feature    21452..21465
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.18"
                     /tool="antismash"
ORIGIN
        1 ctgctgctgg acgcggccct gctggtcttc gtcgtgcccg gcgcgttcct cgggcggtgg
       61 gccgtccaca agatcaacca gcggctcttc gaccgcatcg tcatcgcggc gaccgtcgtc
      121 ggggcggtcg aactcctgct gacctgaccg gatgcgtacg ctcaccccat gcccgcgcac
      181 gtcctgatcc tcggcggcac caccgagtcc cgccgcctcg ccaccgccct cgccgcccgc
      241 cccgggctcc gggtcacctc ctcgctcgcc gggcgcgtga gccggccggg ggcggtcgac
      301 ggcgaggtgc gggtcggcgg gttcggggga gcggcggggc tggccgactg gctgcgcgcc
      361 caccgggtga ccgcgctggt ggacgccacc catcccttcg cggagcgcat cacggcgaac
      421 gcggcggagg cggcacgcgc ggccggagtc ccgcacgcgg tcctgcgccg cctcggctgg
      481 aacctcgacg acgactggtt cccggtggcg tccctggagg aggcggcgcg gctcctgccc
      541 cgcctggggc gacgggtgtt cctcagcacg ggtcggctcg gactggccgc gttcgcgcac
      601 gtgacggctg tccagttcgt ggtccgctcg gtggaaccgc cggagccgcc gctgcccccg
      661 cagtgcgaac tggtcctcgc caaaggcccg ttcagcctct ccgacgagct cggcctgctc
      721 cgcgcgcacc gcatcgacgt cctggtgacg aaggacagcg ggggagcggc gacggcaccg
      781 aaactggccg ccgcccgctc gctctcgctg ccggtggtcg tcgtacgccg gcctgaactc
      841 cccttcggag tacggacgtt gccggacgtc gaggatgtac tggggtggct ggccggggtc
      901 attccccccg agggtgcctg cgcagcagat acgtgtccat gatccagccc ttgcgctccc
      961 gcgcctccgc ccgcacccgc tcgatctccg gaccggcctc cgcgagcgga ccggagacca
     1021 ggatctcgtc cggggtgccg atgtacgcgc cccagtagat gtcgatgtcc tccccggtgt
     1081 actcccggaa cgcctggtgg gcgtcgagca tcaccaccac gtcgtccacg ccctccggga
     1141 gcccctccgc cagccgcctc ccggtggtga tctgcaccgg ccgcgccacc cggttcaggc
     1201 cggtccggtg ccgggcgacc agcgcggaga cactgctgat accgggcacc acgtcgtagg
     1261 tgaactgcac cgcgcccccc gccagcacct cctggaggat gccgagcgtg ctgtcgtaca
     1321 gcgaggggtc gccccacacc aggaacgcgc ccgtgccgtc ctccgtgacc tcctccgcga
     1381 tgagccgctc gtagatcccc gcacgggcgg tccgccagtc cccgacggcc ggcgagtagg
     1441 ccgcaccgcc ggccttccgg tcccgctccg ggtccctggc cgccaccacc cggtacgacc
     1501 cctcgggcag atgcgcgtcc aggatgtcct ggcgcagccg cgtcagatca ctcttcacct
     1561 cgcccttgtc gagcaggaag aacacgtcgg tgccgcgcat cgccttgacc gcctgcaacg
     1621 tgagctggtc ggggtcgccc gcaccgatac cgatgacatg aatctttcgc acccgccgag
     1681 tctgccgcac ggggtagagg gggccggata cgggggcggc cggcgaccgg aaccgggagg
     1741 cccacccggg cgtggtaatg atcacggcgg gatcgacagc gagctaccgc ccacttgatg
     1801 acggaggctc agcatgacga gaacgacccg tgcggcactg ctcctcgcgg ccacggccct
     1861 caccccggcc ctcctcctct ccacccccgc gtccgccgcc gtcgcggcca cgacggcctc
     1921 ggtcacggcg tccacgccgg tggaccagat gtccgacgac gacgtccggg tcgccatctc
     1981 gcgcatactc gcggacccgg cgagcggcga ggcggtcctc cgcgaggcca acgaggcgct
     2041 ggacggcacg atcgcggacc agcgggcgtt cctggagacc ggttaccggc tggcgcaggc
     2101 cgaggacgac cgggtggcca tcactcgcat cctcgcggac cccacgagcg ggaaggcggt
     2161 gatccgggag gcgagcaagg cgctcgacgg gacgatggac gaccagcggg cgttcctgga
     2221 gaccggttac cggctggcgc agggcgagga cgaccgggtg gccgccctcc gcatcctcgc
     2281 cgaccccaag tccagtccgg ccctccgcgc cgccgcttcc gccgccctgg acggcacgct
     2341 ggaggagctg cggtacttca tcgccgtggg gcagtaccag gtgcactagc gccccggcag
     2401 ggagtcgctt cgtgtcgcag gtgggtactc ggcccttccg gtgagcccgg acgtgccggg
     2461 ttccgaggac ggaggcagcc gccatgtacg acagccccct cgcaggccgt accgtcgtcg
     2521 tgaccggggc cgcgcgcggc ctgggcgcgg ccctggccca cgcgttcgcc gagcgcggtg
     2581 cgcggctcgc gctgctcggt ctggaggggc cgcgactgga gggggtggcg gcatccctcc
     2641 caccgccggt gatcgccgtg gaggtcgaca tcaccgactt cggtgccctg gagcgcgcgg
     2701 cggcggaggt acgggagcgc ctgggccgtc cgtccgtcgt cgtggccaac gcggggatcg
     2761 ccgagggcgg ccccttcgcg gggtccaccc ccgagtcctg gcggcgggtg atcgacgtca
     2821 acctggtcgg cagcgccctg accgcgcggg cgttcctcgc cgatctgctg gtcacctccg
     2881 gctacttcct ccaggtggcg tcgctcgccg cgttcggcac ctcgccgatg atgagcgcct
     2941 actgcgcgtc caaggcgggc gtcgagtcgt tcgcccgctc cctccaggcc gaggtcgccc
     3001 acgagtccgt cggcgtgggc atcgcctaca tcaactggac cgacaccgac atgacccggg
     3061 acgccgacca ctaccccgtc ctccgcgaac tgcgcgccca catgccggcc ccggcccgca
     3121 gggtgtaccc ggcggaggtg gtcgcggaac gcctggtcag cgcggtggag caccggcgga
     3181 cgtcggtgta cgtaccggcc tggctgcggc tcgcccagtg ggggcgcgcg gtccttccgc
     3241 cggtcgtgcg gcacgtctcc cgccggacgc tgccccgctt gcaggccgag cgggcgctgc
     3301 cgcccacggg gttgctgggg gcggggggag cggcggacga ggaacggcgg gaaggacggg
     3361 cctgaggaga cgggccgcgg tcgggaaggc ggtcgtgtcc gcagcccgcc gcggtccgcg
     3421 ggtccctcag ccccggtggc cgttcccccg tccgtccgga tgcaggacga ccttggtcca
     3481 gccgtcgtca cgggcgtcga agtgctcgta gcccgtgggg gcctggtcca ggccgagttc
     3541 gtggctgacg acgaagctcg gcttcgcctt cccgccggcg atcaggtcgc gcagcgcccg
     3601 gttgtacctc ttgaccggcg cctgcccggt gccgacgtgc tggcccttga accacatcat
     3661 gccgaagtcg atcggcacct tgccgtgcgc ctccagctcg ttctgggcct gctcgccgcc
     3721 ggggtcctcg ggcaggaaca cgcccaccac gccgatgtcg cccgtgaacc tgaccgagtc
     3781 gatcagcccg ttgagcgtga ggctggcgtc ctcgtgtccc tgggcgtcat gggcctggta
     3841 gccgacgcac tcacagccgt tgtcggcgcc cagaccgaga gtggcgtcct tgacgacctc
     3901 cgccgggtcc tgctcggcgg tgttgaccgg gatggccccg atctcctccg ccttgtgcag
     3961 ccggtcgggc tggtggtcga ccacccagac gcgcccggcg cccttgagga gggcggagta
     4021 ggccgccatc agcccgacgg gaccggcccc gaagacgatg gtctggtcgc ccggtttgac
     4081 gtgggccatc tcggtggcgt gatagccggt ggggaagatg tccgcgagca tcacgtagtc
     4141 ggtctgccgc tcggccgcgt cctcgccgag gcgcagggcg ttgaagtcgc cgtagggcac
     4201 gcgcagcagc tccgcctggc cgccctggta ggggcccatg tcggcgaatc cgtaggcggc
     4261 tccggcgaga gccggttccg gctgcatggt caggcagtag ttggtgagcc cgcgctcgca
     4321 ctgcttgcag aagccgcagg cgatgttgaa gggcagcacc acgtactcgc cgacctggac
     4381 cttgcgcacc gccgggccga cctccacgac ctggcccatg ttctcgtgtc cgaaggtgcg
     4441 accgggctcg aacgaggtgc ggccctcgta catgtggagg tccgaaccgc agatgttggt
     4501 ggtggtgatc ttgacgatga tgtcgcaggg gtgttcgatc ttcgcgtccg gtacgtcctt
     4561 caccgctacc gtgcgcggtc cttcatatac cgctgctttc atgatgactt ctctcggccg
     4621 cggctcggcc gcggcacgtc gatgccggcc gtccacccgg atcgggtgga gcggcggtgc
     4681 cgccgcggtg ccgtcgcagg gggcttcggc atcccgggcg gcgtgccgtc cgggtccccg
     4741 tcggcctccg gcgcgaaaca gccactcacc gcccgatcag cgagacgtcc gggccttccg
     4801 acccgccggc cgccgacgga tctccgcctc aagtctccga ccggtcccgg tcgtcgtcgt
     4861 cctcctggag catgtcccga cgctcctgtt cgcgcttgga gaaggcggct gcccggatcg
     4921 cctcgtcgct ctccaggccc gaccccagcg cgccgcccac cgtggcgacc gaagcgacga
     4981 accaggccaa cgtccagtag tcggtggtgt gcagctggtt ctgggtcgtg gtggcgaaga
     5041 ccttgtcgtt gaggatgaac agcgcccaga ccaagctgac ggccagcaac ccgacataac
     5101 acacgatcac cccgatgccc acggtcaaga cggtcgaggt gttgtagagg ctcgtcctcc
     5161 tcttctcctc cggcagcgcg ttcgctggtc gatgccacag ctgcgcgtcc acgatcagcc
     5221 agccgatcat gatggcgacg gacccgaccg tggagatcac gaggcggggg gtgctcaggg
     5281 cttgcgacag gctccagacg gtggagttca cggtggccac ggccccggtg gcgagtgcgg
     5341 ccgccagggc cttggacaga cccggcacca ggcgccacgg ccggttggcg cggaccatgc
     5401 cgacgagcac tctcaggtag ccgcgcggcc cgccgacgac gtaccggaga tccgcggcct
     5461 cgtcctcgtc gaccgggccg gggtggatgg gggcgaaacg gctgacgaag tgtcccagcg
     5521 gccggctctg cggatgccca tcggttccgg gggtctgcgg ggcggccagg gtgaggacca
     5581 cttgttcgac ggcccgtgcc gctctggtct gcaggcgcag gccgcccagc gtgggcaggg
     5641 agagcagcgc gaggccgtgt tcgtggctga gttccacgac gagtttgcgc ccgtggacgt
     5701 ggagcggaag gtcggtgatg gccacgacga tgtcccagtc ctccgtcctg gcacggtcca
     5761 tgatccggcg caccagggtg ggcgggtcct ccgtccccgc ggtgaagggc tcgctgacca
     5821 cgcggaactc gaaccgccgt ccgtcgcccg cttttttggc gagggggtcg gggagggtcc
     5881 gggccaggcg ccgcgcgatc tccgtcggcg cgtcggggtc cgccaggaga gccacgaccg
     5941 taacgtcctc ggacgacacc agcgtgactc cttctcagtc ggctgccccg cgatcgcggg
     6001 tgccccacag catgcccccg gggccacctg ggcaccacgt gacacgcggg ccccgcccgc
     6061 ggcgcgccgg gcggccgggt cgcgagggcg ccgggtgctt cccgccgggc cggccgcgcg
     6121 cgtcagcccc gccgcagacg gggtccctcg gcgccggcgt cgacgggggc ggaggccgcc
     6181 tccacccgcc cggcgaggtc cacggcccag gtcgcgaggc cgggcaggtc gaggtcgtag
     6241 gggtggggct ggttctggcc ggaccaggcc gtcaccgccg cggcgccccg gcgcaggagg
     6301 cgggggccgc ccgtgatgtt gccgcgggcg gagtgggtga ggcccacggc gatctgggcg
     6361 aggccgcgcc acagctcgcg ctcggtgtcg gggccggact tccaggcgtc ctcgaacacc
     6421 tcgtgcgcgt ggaacggctt cccctcgtcc agcagcgcct gtgcctccgc gaccgtctcg
     6481 tcggggctcc gtacgacccc ctcgggctgc cgctcgaccc cggcggaccc gtagggcaac
     6541 ggccgcccca gcccgtcgcg ggggcgggcg ttccgggccc gcccgtcggt gtcccggtcg
     6601 cgtccgccgc tgtctccgcc cgtctccgcg tctgtcatgc ggccgattct gccccgtccc
     6661 accgacaacc cgcttcggag gagtcccgta cgtggggtaa agtgctgttc gcgcgatcac
     6721 gcgggtcacc gcgagtgagc gcatcgggac gtggcgcagc ttggtagcgc acttgactgg
     6781 gggtcaaggg gtcgcaggtt caaatcctgt cgtcccgact ttacgaagtc gcaggtgagg
     6841 gccggttacg gagaaatccg caaccggccc tcgatcgttc ttggggacca gtgggggacg
     6901 agtgcccttg accggggtca gcgggtcacg acgatcgggc ccggcagcga gcgcgcgcac
     6961 ggcgcctctc cggcaaccgg ccctgaccag ccgccatggt cggtgtcagc gcagtgagcg
     7021 ctggtactga aggtcctcgg tggtgaagga gaagatcagg cagtagcgca gcccgccgcg
     7081 gagtgctccg accgcgtgga acgacgactc gctcatcgcc atgcctgcgg ccgtgttgtg
     7141 caacgggggg tactggacgg ccggcgaggt ggactcctgg ctgtcgaaca ggccaaggat
     7201 gccgccgtcg gcctcttccc aggaccggtt gaagtacgcg atcagacgat gcgtgaagaa
     7261 gtacttgtga ccggtgtccg gattgaagtc ggagtgcacg gcggtaccgt cgcccggcac
     7321 gtaccggttg gcgagcagga agtggtcggg gcggaagcga accttgaagg acgactccat
     7381 cagctcgcgg acacgggaga gcttgtcctc ggtcaggacg gccgccaggt cctccgggag
     7441 gctgtcggcg gcgaagtggt ggacgtcgga cttgtagtgc tgctcgctct tgctcgtcca
     7501 gccgtcgaat cgttccagcc acccgagcac ggcttcggcg tcttcggagc cgaacaggtc
     7561 tgtgacggtc aggtgcggga acggggcggt tcgtacgtcg atcttcatgg tgtccgtgag
     7621 cggcgtggcg gggttcggca tgtcatcctc cgtggtgact gaaggcgttc tcaagcgcct
     7681 cgctggtgtt gtcgggtccc atgacgagca cagcgcgtcg ggcgagcagg cgttctgccg
     7741 cggcgtcgac ctcgtgcgga gacgtgtccg cgacagtcat gtagtggtcg cgcaaagatt
     7801 ccgggccgga tccgtggggc gggtgtccga cgagcaggtt cgccagggcg cggggttcgc
     7861 acagggcgcg ttccagcttt ccggccaggt ggctcttggc ccggtcgagg cggtcctcgt
     7921 cgcaccggcg ggggcggctg gtggcgagtg cgactgttct ggtcaggagc cggaagtgct
     7981 gcggagcgac cggcagccat gtccacaggt gtggcagtcc ggcgcggcgg tggacgacca
     8041 tgtcgggtgc gtaggctatg cccagccgtt ccctgaggat ttccacgagg tcagccgcat
     8101 gactgccgcc gaccaccgtg gcggccagtt cctcggccgc cggtgcgccg gagagtgggc
     8161 acacgatgcc caccgcggac acgtcgtgcg tatgccggcc ctcgtgaggt ccgctgggcg
     8221 aatccggagc gttcacggcg ggggagacgg acggggtgtg ggaggccgcc caggtcggta
     8281 tgtccgcgcg gtggtccacg ggaccgacga ccaccagatg ggcacgcccc cagtccggac
     8341 gggtgtggtc ctcagccggc gtcctgtcgg gtcccgccgg gaggagcctc agcgcctgtc
     8401 gacgagcgac gtcctcgatg gattcgtcgg gagaccccga cgcgaccggc tctcccggtg
     8461 gcagtggtac agccatgtcg ggcatcagtt ccgggaggcg ggccagcgcc gtgagaaagg
     8521 ccagggaacg ctcgggtgcc acgtaggcgc tgacgctcag gccaccgatg gcatccaccg
     8581 ctttcacgcg cgcaccgtgg cggaagggag cggccaggag ttcccgcagg cgtgcgttca
     8641 cgggacgggt gtggccggcc gcgggccatg cgggacgcgt ccagggcagg aagagccgga
     8701 tctccaccgt tgttccggac atcggcacga cgtggttgcc cggtgtgcgg cgggtgtcgt
     8761 ggccgagttg tgcggccgtc cgatgtgccg cggcgcgcag ggcggcggca ccgggggact
     8821 cactcatggg ggagcaccac ccagcccgct tccaggacga gcgcggcagc ctcggccacg
     8881 tccgcggcgc tgaccgatgt cagttcgtcg cagcgtgcct gggtgaaggc ggggtcgtcg
     8941 tgcaacaggg tgtccacagc ccgccgcacg gtgtactcga cggggtcggc ctccggcctg
     9001 cgcagggtga gcagtctgct cgccgcccag ccttccaccg tcgcggcggc gggcggggtc
     9061 cggacaaggc cggacagcag gtcccgtacg gctgtgcgca gacggtcagg gctgcccggt
     9121 gcttccaccg tgacgtacca gggatcggac atctggcagg gctcgtcgaa catgccccag
     9181 taggcggtgg ctccgagagt gggggcgagg atgtcgttca tggcctcgac caggacgagc
     9241 agagcggtga actgcttgtg gaccgaggga ccggacaacg cccaggcgag ggcgctgccc
     9301 gtcgggtgtg aaggcacggc cggagacggc atgcggtggg tcctcgccgc cccccggccg
     9361 ggcctcgcct ccatccgcgg gggtgcgaag gactcctcca ccaccgctac ggcctcacgc
     9421 tcttcgaagg gaccgcgcag ccacagcacc ggacgtgctt gctcgtaggc cgaccggtag
     9481 aacgcggcaa cggtcgcggg tgtgggcgcg ggtgccaggg caggcgccgc gtatccgtcg
     9541 tgtgcgtggg ccgggtcggt gaacagggcg cgggggacat cgacccacgg ataggtcccg
     9601 cgcgggttgc cgaggagctt ctcctggacc tctgcggcca ccacggcctg ctggttggcg
     9661 atgacgtcgg ccgaggcgag ggtgccgtgg aaccggtcgc cctccagacg gaggatctcc
     9721 tgccagtgcg tggcgcgggc gccgccgaag tgcacggtga agtccgggcg cgtgcgggcg
     9781 ttcgcgatgc cgccggccgc ctccacgcgc cggaagtagt cgagtttggg atgggcgtcg
     9841 gtgccctgga acagcaggtg ctcgcacaga tgcgccagcc cgtgctcgcc ggggccctcg
     9901 ctacggaacc cgaccggcca ggcagaggcc caggtgaact gggggcccgg ggcccgttcg
     9961 acgtggacgg acaggcccca gggcgcagtt ggggcaggta tcacgagacg accgcgctgt
    10021 agagaacgta ctcctcggtg ggaccgagcc cgaggtaccg gtgcatgcgg tcgtcggcga
    10081 acccgcctat gggtgtcacc gccgatccga ggtcggtgcc caccagaagc aggttgtgca
    10141 tcaggtgtcc ggcctcgatc agggagaagc ggtaggcgcg gtcgccgtac ttgacggcgg
    10201 accgggacag ttcggcgctg agcagaacga cgcagcgggc gtcggcgatc cagtcgtgcc
    10261 cgaagacccg gcgcagtcgg tcccgctggg ggccggcggc cagctgctcc agagcgtgat
    10321 cgaggggccg gtagtggtag agcccgctgg cgacgccctc gcagcggctg acggctacat
    10381 acacttcgac cgggaagcgg gcccccgcgg aggggtatac gcggcgcgag ccgtggtcga
    10441 cggcggtcgg cttgatccgg gtcgattcgc gcagcagcac cgacagtgtg tccagtgcga
    10501 gtggttcagc gacattggcc cggtcggagg agcgctggac gagagcctcg gacagcgaga
    10561 gctgggattc ccacggcacg tcgggcaagg gcagcagcgg catgcggggg taggtcttga
    10621 acacgatgtc cagccaggcg cggggccagt gcgccacgga ggtccagttc tcgctctcca
    10681 tgtaccggcc ctcggtggag ctggcggcgt gaaagtcggg ataggcgaag gagtgtgtcg
    10741 acacggggaa cctcacaact acaggaaggg gtgcgggacg tcgttgagtt ccggtgtttc
    10801 ctgcccgtgg cgggcaccga gggagagcag cctgcgcgtg aagatccgca gtggttcggc
    10861 cagatgcatc ggttgcagtt cgggtacgac ggccttcatc accgagacac ccagttcgcg
    10921 cacgtcgtcc gtggtcacgt ccaccagcac gatgtctccg acacggtcga gcaactcctc
    10981 gaccagcccg cgcatggaac cggcacggtc ggcgaaggcg cccggatcgg ccggggcgcc
    11041 cgcgtcttcc aggtagctca accgggacga ccggcccggc tgcatccagt agtaggtgcg
    11101 ctcctccaga cagttgatgt cgaagccggt gtgcagatgc tgttcggcgt actgacgggc
    11161 gtggtccagc cggtcgcgca gtccgcgccg gaagcagatc gcctcgagca cggcgccgac
    11221 catggcgtcg gacagggaca aggacgcctt ggaaccgact gtcatctccg ggcccactcc
    11281 ggagcgatcg aggacctggg cgaccacgac atgcacgggc aggtcggtgg gtacacggaa
    11341 gagacgtatc tccaggtggt gccggcgggc gtcgcggagc agctcaagca ggcggtcatc
    11401 attgacggcg ccggcgtcca gggcgtcggg caccaggttc agatagtgca tcagcatgac
    11461 ggcatcgcgt tcgacagctt cgagcagtcc gcgccgtgcg gccgcggccg gcgcgagacc
    11521 cgcggccgcc cccgtggtca gcggatctcg cagatagcct tcgtcctcgg agacgtagta
    11581 cggcagaaac accgtctgcg ccggcacgag gacgacggct ccggtcgcca cggacgtgcc
    11641 ccggacccag gcgcgctcgg tgccgtcgac ccgacgccgc tcgttctcgg tcgcggtccg
    11701 tgcgcacagg aagcgtgagg gggcgacggc ctgcgcgccc tgggcggtca gcgcctcatg
    11761 gctgccgcgc aggaggtgct cctcgcggta gacggacagg ctgtaccgct cgaacgcttc
    11821 gaacagtgcg ccgaccgtgg tcgtaccggc gtcgaagccg cgcccgcctt cggcggcgcg
    11881 cttggtgtag ccgctggagg acagacgatg ggtcggcacg acctcggcgc ggtggagcag
    11941 ggtggccggt tcgtcgttgt agtagtcgcg ctcctcggcg aggagccgca cgatgccgac
    12001 gtcagaactg acagcggtgg tgaagcgggg cagcagggcg cgggcgtccg gctcgccgcc
    12061 gtcgacgaga cggtcgaagc tgagacgcgg tgccgtgtcg tggcgggagc ccggcatcgt
    12121 gccgcgggtg tcttcgggcg ccgcccatcc gggtgcggag agtgtcatcg gctgtgcgta
    12181 ccttcccgga cgacttcctc ggtcagcgcg caggccctgc aggacggcac cgggaagaca
    12241 gcgtggacgt caccggagaa ggtggcctcg tcgagcaccg agaccttgct gaccagagcg
    12301 ggcccgaagg cgccgtggcg caggcgggag atctcacggg ccagcagcgc ggtggccatg
    12361 tgcagtccgg tgctgttcgc cccgggctta ccggccgagc cggggatacg gggccgcgac
    12421 cgggtgatcc attgcggggt cgcggcgtcg tcctccatgg tgcgccgggt ccagtagcac
    12481 tcgaagcagg ccgagccgcc gggaatcacg gtggggccga gggtgacagt tccggcgccg
    12541 agcatcgcgg tgaggaaggg cgagcccgag cgcagggcgt cccggttcgc ctcccggaac
    12601 agtccgatct cggtggcgtc ggcgacaacg accacggccc ggctgccggg ggccgcgacc
    12661 tcaccgggga cccagtcgac gatctcgggg gtgggatctt ccccgtcggc ctgctcggag
    12721 agcagaccgg tgaggagcga cgccgcgcgc ggcagtcccg ccacggagat ccgctccagc
    12781 ggccggctga gcggggcggg ttcggccggg tccgtgaaca cgccgcgtcg ggtcagctcg
    12841 gcaaggaagt ccgtagcctc ctcacggtcg acgccgcgct cggccaacag ggccacgagt
    12901 tcgccggagt cggcgccacc gtcgatgacg cggtgccaga ccacgcccag aaggtcaccc
    12961 cacaggccgc gcagggcaaa gccggagcga gtggtgctgc ggtagacgac gacctctttc
    13021 ccgtcgtcga agagggccgc gtccgcggcg atttcgaagg tgctcatcgg ttttccgctc
    13081 cccacgccag gaggcggccc agaccagggc cgtccagttg tccgaaccca cgaagtccgg
    13141 tgatgatgcc gtcggctgtg gcactgtccg ccctgggcag gctgcccgcc agtttcgccc
    13201 gggcccgtgt ccagtccgtc gtcgggggca ccacctcgta gacgacggtg aggctctcct
    13261 cactaccgtc gcggcgcctc acccgcacga agccgggaag ggtgtccccg agcggtccga
    13321 gctcaccggg aacctcctcg acggtcacgt cgtaggcctg gtgtgccagt acggcgtcag
    13381 ccacagcggc ctcggtgaag agagcgggtg tgacggcgcc gcgtgtcagc aggccggcca
    13441 ccgcgtacgg gagggagaaa cgggcttcct ccactgtgcg cggccgctgg tacttgctcg
    13501 ccgtggccac gtactcgggt acccccagcg tcacgcccag cgcgtcacgc aagaagccgt
    13561 tccctcggag cgactccagg tggtccaggg gtgcgtcgaa gtagccacac agcgggtact
    13621 tcttgtaatg ggtcggcagg acgtccagag cccagggatc gccgaaccca tggacaggca
    13681 aggagagctt ctcctggagc agcgcttcca gcggcgcgta ccaggcgtcg actcgttcgc
    13741 tctcgcgcag ggacgccgcg cgcaggcccg cttccaagcc tccccggctt gcggccgcga
    13801 cctgatgagc cttgccgacc gtgccgtgcg cgcacgcgta gccggactgc gaggtgaggg
    13861 ccaggaacat ggccgtgctc agagccggcg ggccgaggcc gagagaaccc gcgaccgcgg
    13921 cggcagtggc cggcgcaccg aggaccggtg tcgcgtggaa gccacgcttg cgcagctgat
    13981 cacccacgga ctcacccagg gtcaccatgg tctccaggcc ggccaggtaa cccctgatca
    14041 cctgctgtgc ggtgaccagt ccgcactcca gcagcgcgag gagcgcgggc agcagaaccg
    14101 ctcccgggtg cccgacggcc atgtagtgga tgcagtcgaa ctcgctcgcg tgcgtggcgt
    14161 gggcgttgtc gtaacaggcg gtggaagggg agaggagacc tcccgtcgtc caagaagtcg
    14221 cctggtctcc ctcacggacg accggcctca gcgggacggc cggcaagggc tgcgcggacc
    14281 aggcactcgc gagggtgtcg accagagtga aggtgaactc ctccacatga cagggtgccg
    14341 ggggccggga catggcgccg gccacgccct cgggcaactc gttccagttc atctcaggct
    14401 ttctccgcac ggacggcgga cgaaggcggg ccacagggcc gcgagggaca acggcggtgg
    14461 gccgacagct gtcagcaagg cggcgctggg ggcagacggt tcggaatcag cgcttgatcg
    14521 gttctggaga aggctgttct gtatgcggac gggggcggtc gccggccgac gtagtggccg
    14581 tgaccaccag agatcccccg agcaacagcg acgtcagcag cactccggtg gtgggcgagc
    14641 agaaggagac ggcgaatccg gcaagcgtcg ggcccagggc ctgcccgagt tgcatgaccg
    14701 tgttgttgag cccgaacacc gtgccacgcg tctcggccga ctcccgccgc gccagggcga
    14761 ccgtgagcaa ggtgaaaacc tcgcacaaca ccacgcagta caacgcgtat gccgcgagca
    14821 ccgtccacgt cgtgcgggcg gcgaacagca gcacgctggc ggccgctcca cccgtgaaca
    14881 caccgagaag aaggacacgc gtacccagcc ggtccgtcag ccgtccccag ccgtaggcgg
    14941 tgaggagcga cgccacaccc ccgaccgaga aggccagacc agccagccga cgtccggagg
    15001 caccgccgac ctcggcgagc tggagcggca gcaacacctg cacaacggcc gcggccatgc
    15061 tggtgagcag caccaccgcc aggacggggc gcagacccga cgtgccgcgc gcaccgaggc
    15121 tgcgcaacgg ttggagccac agatgccggt cccacagcgg tggtcgctcc gcaccgggcg
    15181 ccccgcgttc acggggtacg aagagggcga gcaggaagca cagcgccatg agcgcggcgg
    15241 ccaccgcata gaccaggacg aaggagtcgc cggtcgtcag caaagtaccg acggccggac
    15301 cgagcagggc tcccgcattg cgggccaccg acagcagact catggtgcgc ccgagacgtt
    15361 cctcggggac atgacggctc aacagggctg tcgcggcggg gatgaacccg gaggcgaggc
    15421 ccgccaggac gcgcagcgcg aagagactac tgggtgtgac ggccagcggg gtgagtgcgt
    15481 acaccacggt caccgcggcc gccgcgcgaa gcatcatcgc gcgctggccg aaccggtccg
    15541 cgagcgcgcc ccagaagggg ttgacgatcg cgctgaccag aaacgtcacg cccacgatgg
    15601 gccccagcca ggctccgaca tgcccgtgcc ccaggtgcgc gacgtagagc ggcagaatcg
    15661 ggaagttcag atagaaggcc gccgaagaca ggaaggtggc gaaggtgact gccaggactg
    15721 ccggtctgct ccatggcgtc gacccgccgg cactgggctc tgtcacgtga tgctccttca
    15781 tgctccccgg acgcgcgtac cctggtcaac gtggtggcgg cgcgatgcga gcgcgccgcc
    15841 accacatctc aggaccgcga gggtcagagg gcggtacggc cgttgtcgga cgaggcgttg
    15901 atgagcgcgc ggccgttgtc ggacgaggcg ttgatgagcg cgcggccgtt gtcggacgag
    15961 gcgttgatga gcgcgcggcc gttgtcggac gaggcgttga tcagggcgcg gccgttgtcg
    16021 gacgacgcgt tgatcagctc ggcggtctca gcggtgcgct cggtaccgaa ctcggcgaat
    16081 tcgaaagaca tgttcgatcc tctcgtggtg actctctgtg cagccgaagg tggcttgcgg
    16141 cgtgatcgtg gcatcacgcc gacgaggcga tcaatagggg aacgctttcc ggtcaggcgt
    16201 ccaaaatccc tcccttgaca cccacgggcc tgctcgttca acaagacgtt gatccacggg
    16261 aaagtaaaga gctcagtatc gatgggccat acattcaaga tcccgcaaaa gcccgacctt
    16321 gaccctgagg taatggaatg tcactccagg tgatctcgct ggcgatcatt cactctccgc
    16381 catcatcgcc ctgtgttgtg acttgaatca ctcgtgaaaa ttgctcgggc gaatgacgat
    16441 gcatgtccgg agccgtcgcc cgggctcccg gctaccagcc gatcgccgga agcgggttga
    16501 gcgtgcgggg cggccggagg cgctcgagcg gaacgcggca gtcgcgggcc ggcgcggcgt
    16561 cgatcgctgg ggcctcgtcg aacggcagcg ccgtcccctg gccgctcacc gagtacgggt
    16621 gagggccggt cgcggaggca ggccgagggc ctctcgccca gggttccccg gtgctgcgga
    16681 cctcgggcag gtcagatcgg cgcgagggtg gacggtccgg tggttcgttt gcaggagctg
    16741 accggcgaag ggcacgtctc gcttctccgg gaatcgtcag cccagggcca gttcgcgcag
    16801 cgtgcggacg ccctgcttcc cccatcgggc acgatcatcg tggtccggtc ggtgtccgcc
    16861 gccacccgcg ggacatcacg tcggaccttc tgggccggtg acccggtcac ggatggaacc
    16921 gccaccggcc ctccgagacg acgtccacct tgtcgccgcg cacccggacc gccgtgtcgt
    16981 cgtcgatgaa gtggatcggg aagtccgccc gcgcgacgat gcgatcggcc caggcgtcgt
    17041 cgcgttccgg gaagtccggt gagtacagat ggggcttcag gtacgagtcg agcaggccga
    17101 agggcggggt cacggtggac gcgccgagca ggcggaggtc cgccgtgtcc ccgatgacgt
    17161 cggcggagtg ctcggtgaga tgccggctga ggatcatcga gccggcgctc agccccacgt
    17221 agacccggtc ggcaagggct ttcaggaagc cgtcggccag gccgttgccg gtgatgctgc
    17281 gggcgaggtg gtagtggttg ccgccgccga cgtagatgac gtcggcgcgc agcagccggt
    17341 cgagcaccag ttgccggggc aggccgttca gctccaggat gtcgaactcc cgccagccga
    17401 gaccgtgtac gcgggtcatg tcggcgagga gccagccgtg gtcgccggac tcggccatgg
    17461 acgcggtggg gacgtatacg aggttcgccg agccgaacgg cctgcccagc atgtcccgca
    17521 gggcgtcctt cagggactcg ttgcgcaggc cggccgacgt cagcagaaga ttcatcggcc
    17581 gagccaatca cgggtgccgg ccgtgggcaa cgccgtgcgg tacgggtcgg caggcccggc
    17641 ggagtccgga gccgacggcg cggggacgag tcgtgcgcgt cgctcaggca ccggggagga
    17701 agaggcagaa cagatggccg tgcggatcgc gcagcacgcg gacgtcgttc tgcggctggt
    17761 gttcctccac cgtcgcaccc agggcgcacg cacgctcggt ctcggcggcg agatcgtcca
    17821 cctggatgtc gaggtgggcc tgcatctgct gctcgccggg gccggacggc caggccggcg
    17881 cgcggtggtc cttctccagc tggaagctga gaccggggcg ttcatgctcc ggagccttga
    17941 gccggaccca gtcgggctca cggtcgacct cgtcccagcc caacagggcg cgatagaaat
    18001 cggccagcgc ggggggatcg ggggtgccga gcacgaaggc cgcgagcagt gtcgtcatgg
    18061 ttcatcactg cccgcagccc atggtcgtac gcgtctgtcg tacgcgcccg gaattcgatt
    18121 tcggcgtcag tttccgacgt accagtggaa tccgccggtg ttcgccgcca cgatcatgag
    18181 aatggcgaag accacgaggt cgacgatgcc gagaacgacc gccgccttcg ccattccccg
    18241 accgccccgt gcgcccggct gccgtgtggc gaccatgccg aggatgatcg ccagggggcc
    18301 gagaacgaca ttgaggaaga aaaagccgac aatgccgcac accaggcccg cgatagcgag
    18361 accgttggcc cgcgaaccgg atcgagcggt cggctggcca ccgtaactgg tcatgagaac
    18421 tcccgttcca tgaaaggggg aatgccgtta ctttgtgtct ctgggctccg ggtgcccagg
    18481 gggagttgcg gcattcccca ggaatcccgg ggttaagcgg aaccccggat tcacgactct
    18541 cgtgccgaaa gcgggatctt ggtcccttcc ctcgctgccc cgcgccgagc ttcggaggca
    18601 ctcgcgtcgt tcctcgtgca acctcggggt gtcgcgcctg cccgaggtcc gattccgggg
    18661 ccagggcgct actccggcca ccccggggta ccgggtgctc acccaggcgc cgattccggt
    18721 gatctgagca aggcccggaa cacaggggga gcatgatgac taccgcctcg gcgaagcggc
    18781 tgcggaagag cgcggcggac gtgttcggat gggaggagct gcggccggag caactcctgg
    18841 cgatggaagc ggtgatggag cggcgggaca cgctggtcgt gatgcccacg ggagccggga
    18901 agtcggccgt ctaccaggtg ccggggctgc tgctgccggg gccgaccgtc gtggtgtcgc
    18961 cgctcgtcgc gctccaacgg gatcaggtac gcgggctgct gaaccgggag ggcgcggagg
    19021 cggccgccgt gaactcctcc cagagcggca gcgagaacgc ggcggtctgg gaccggatca
    19081 gcgagggtga cgtcgacttc ctcttcctgg cgcccgagca gctcgccaag gacgaggtgg
    19141 tggagcagct cgccgccgcc gagcccgcgc tgttcgtcgt ggacgaggcc cagtgcgtgt
    19201 cgtcctgggg gcacgacttc cgccccgact acctgcggct cggccaggtc atcgaccggc
    19261 tcggccggcc tcccgtactg gccctgaccg cgagcgccgc cgcacccgta cgggccgaca
    19321 tcgtcagtca gctcggcatg cgggacgtgc gcgaggtggt caccggcttc gaccggccca
    19381 acatccacct ggaggtcatc cccttccagg acgccaccgc caagaagcga gccgtcgtcg
    19441 aacgcgccgc cgcggaggcc aagcccggcc tcgtgtacgc cggtacgcgc cgggaggccg
    19501 aggagtacgc cgaggaactg agcctgctcg ggctggacgc ggccgcgtac cacgcggggc
    19561 tgcccgcgcg ggagcggggc gaggtgcacg accggttcat ggcgggcgaa ctggacgtgg
    19621 tcgtggcgac ctccgccttc gggatgggca tcgacaagcc cgacgtccgt ttcgtgctgc
    19681 acgcctccgt ccccggctcc ctggacgcct actaccagga gatcggccgc gccggacgcg
    19741 acggcgagaa ggcccgcgcg atactcgcgt accggcccca agacctcggc atgcagcgct
    19801 tcttcgcagc cgggcggccg gacccggaca ccgtcaccca ggtcgtgagc acgctggagg
    19861 aacacgacgg gcccgtcccg ccgaccgagc tgcgcgagca gaccaacctg acgtcgagcc
    19921 gcctcacagc cgtggtcaac ctcctggagc aggtcgacgc cgtgcacacc accgaggacg
    19981 gcgaactgga ggcgaccggt acggccggac cggccgacgc cgcccagcag gcgatcgaac
    20041 tgggcgacgc ccatcagcag ttggagcgtt cccgtgtcga catgatgcgg ggctacgcgg
    20101 aggccaccgg ctgccggcgg cgcttcttgc tgggctactt cggacaggga ggcgagcagg
    20161 acgagtcctg cggcgcctgt gaccggtgtg aggcggcgga actggcggag gagggcggcg
    20221 cggagtgcgg acccgccgtg ctcgccggca cgggcgggcc gatacccgag tcgacatctc
    20281 cggcgcccgc cggggacccg catcccttcc cgcccggcac tctcgtacgg cacgagcagt
    20341 gggggcaggg gtcggtcatg agcgaggaga acgagcggct gacggtgctg ttcgagacgg
    20401 tggggtaccg gacgttgtcg ctcgaggtga tcaacaggaa ccagctgctg accgtgtgct
    20461 gagggggtgg gggcgcacat gtgggttccg gacatgtgcg tcccccacgt gtgggccccg
    20521 gacatgtgcc gtccccacac gtggcttccc cacaggtggg aggcgcacat gtgggccgac
    20581 cccgcccctc agcccagctt ccgcaccacg gccagtgaca ccgccgccgc cgcgaacccc
    20641 agcaccgcgc ccgccgcgac atcccccgga tagtgcaccc cggtgtggac gcgggagtac
    20701 ccgacggcga ccgccaggga ccccaagggg accgcggccg gaggcaggac gacgcccacg
    20761 gcagtggcga aggcggtggc cgaggccgtg tgcccggagg ggaaggacgc cgactcgggc
    20821 atgcgcacgt gccgggccac cgccacctgc gcctgctccc ggtcgggccg gtggcggcgc
    20881 accatccgct tgccgagcag gttcgccgcc gccgatgcca gcgtgaccga aacgaccccg
    20941 gccagtgccg cccggcgcgg ccggcccggc agcagggcga gccccgccgc gacgccgaac
    21001 gagatcttcg agtggtcggc cgcgtgcgac agcagccgca gtgcccggtc cagcgcgggc
    21061 gtcggcgtgg cggccacggc ggcgtacagc gcgccgtcga ccgcgcggag gtcaccgagg
    21121 acggcggagg cgatgtcgcg gtcagccatg gttctctcct ggtgccgtgc gctcggcggg
    21181 gccgaacgcg aggtcgagca gtttccgcca gtcgacgggc ggcgcgggcg gcggcacgcc
    21241 gggacggtcg cgcggcagca gcacccgcag ggcgcgtggc cgtaccacgc aggtgacggg
    21301 agtgcgcagc cacagcgcct cgccgtccac cgccaccggg atctgctcct ccccggccgt
    21361 cacctcgacc cggtgcgcgg tcgtcacggt gagccccggc gcctgcgtac cccgtacggc
    21421 caggtccgcc gcctgggccg cgttctccac cctgatcccg atcacgccca gctcaccggt
    21481 gtcgagccgc ggccggcgcc cgccgccgct cagctcgtcg ggggagacgt acgggttgtt
    21541 gctgatcagc agcgcctgct gttcgacgag gcggtcgccg tccacgttcg cggcgagccg
    21601 tcgtacgcct tccctggcca gcaggtccgg catcaggttc agggcggtgc cggtcttgtt
    21661 gtcgcggtac tcggggctct gcacgatgtc cgcgtagacg ccgaaggaca ccgtgttgac
    21721 gaaggggcgg ccggagacgt cgccgaggtc gacacggatc tcctcaccgt cggccagggc
    21781 gtcgaggcag cgggccgggt cggtgcggtc gaggccgagg tccatcgcga agtggttgcg
    21841 ggtgcccgcg gagatcacga ggaacggcag gcggtgctcg gcggcgaccg ccgcgaccag
    21901 cgcctgcgta ccgtcgccgc ccgccacccc cagcagatcg gcccccttgg ccacggcttc
    21961 ctcggccagc ttggtcacgt cggcgggttg cgaggggtcc agcaggatca ctcgcgcgcc
    22021 cagatcctcc gcccgtctca ccaggtcgaa gcggccgacc ttgccgtcgc cggacttcgg
    22081 gttcatgatc agcaccggat gtctcggccg gcgcgctcgg ctgggccgct gggtccggtg
    22141 cggtcgtgcc ctgcgcagcg ccgcacgg
//
