LOCUS       NZ_SGWQ01000013        16076 bp    DNA     linear   CON 10-APR-2024
DEFINITION  Herbihabitans rhizosphaerae strain DSM 101727 Ga0310478_113, whole
            genome shotgun sequence.
ACCESSION   NZ_SGWQ01000013
VERSION     NZ_SGWQ01000013.1
KEYWORDS    WGS; RefSeq.
SOURCE      Herbihabitans rhizosphaerae
  ORGANISM  Herbihabitans rhizosphaerae
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Herbihabitans.
REFERENCE   1  (bases 1 to 150197)
  AUTHORS   Goeker,M.
  TITLE     Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing
            the most valuable type-strain genomes for metagenomic binning,
            comparative biology and taxonomic classification
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 150197)
  AUTHORS   Goeker,M., Huntemann,M., Clum,A., Pillay,M., Palaniappan,K.,
            Varghese,N., Mikhailova,N., Stamatis,D., Reddy,T., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-FEB-2019) Prokaryotic Super Group, DOE Joint Genome
            Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.12.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 226.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004216555.1-RS_2024_04_10
            Annotation Date                   :: 04/10/2024 19:27:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,690
            CDSs (total)                      :: 6,628
            Genes (coding)                    :: 6,561
            CDSs (with protein)               :: 6,561
            Genes (RNA)                       :: 62
            rRNAs                             :: 3, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2 (5S)
            tRNAs                             :: 54
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 13 of 67
            Pseudo Genes (incomplete)         :: 59 of 67
            Pseudo Genes (internal stop)      :: 5 of 67
            Pseudo Genes (multiple problems)  :: 9 of 67
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:31:17
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 109688
            Orig. end                         :: 125764
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            SGWQ01000013.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..16076
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="aminopolycarboxylic-acid"
                     /region_number="2"
                     /rules="(AesA and AesB and AesC)"
                     /tool="antismash"
     cand_cluster    1..16076
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(AesA and AesB and AesC)"
                     /kind="single"
                     /product="aminopolycarboxylic-acid"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..16076
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:11076](-)"
                     /cutoff="10000"
                     /detection_rule="(AesA and AesB and AesC)"
                     /neighbourhood="5000"
                     /product="aminopolycarboxylic-acid"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..11076)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(AesA and AesB and AesC)"
                     /neighbourhood="5000"
                     /product="aminopolycarboxylic-acid"
                     /protocluster_number="1"
     misc_feature    complement(230..244)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.08"
                     /tool="antismash"
     gene            complement(446..1495)
                     /locus_tag="EV193_RS28765"
                     /old_locus_tag="EV193_113102"
     CDS             complement(446..1495)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1033: iron
                     compound ABC transporter, periplasmic"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005153016.1"
                     /locus_tag="EV193_RS28765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_113102"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_207222847.1"
                     /transl_table=11
                     /translation="MTLRKIAAVLAALSVGAVLAGCGAASNDAGARPVSAGEGVTKYPL
                     TVENCGKKVTYGATPRRVVTMNQAAAEILIHLGVGGRIVGTGYEIDQIPPEIAGEYQKI
                     PKLSAHGQEIKHEALLQAQPDFAYASFASFFTPAQSGERDVLHGLGVPTYLTEFDCVYH
                     QSVAGARFELLFDEYRNLARIFDVPAAGNKLIAEQQAVINSGLETAKGIKAAKDPLTVM
                     WFYSTFGGKPWAAGTGGLPQHVSEMVGVKNVFDDASTKWPEVSWDSVAARDPDVIVIAD
                     LTRGEPGDTAKEKIDLLKKDPLTSKLEAVANDRFVIIPGRYMDPSYGSAYAVPALAKGL
                     VELVQRGLR"
     misc_feature    1519..1534
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.25"
                     /tool="antismash"
     misc_feature    complement(1522..1537)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 22.24"
                     /tool="antismash"
     misc_feature    1525..1540
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 21.2"
                     /tool="antismash"
     misc_feature    1527..1541
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.03"
                     /tool="antismash"
     misc_feature    1528..1541
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 16.11"
                     /tool="antismash"
     gene            complement(1582..2568)
                     /locus_tag="EV193_RS28770"
                     /old_locus_tag="EV193_113103"
     CDS             complement(1582..2568)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013648.4"
                     /locus_tag="EV193_RS28770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_113103"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_165401539.1"
                     /transl_table=11
                     /translation="MSRRGFALVPVLALVVATAGCVDTNQAEARGGVLIENCGTSIRVE
                     HPPARAVAADQETTEILLALGLRDRIAGTALQIGPVAPEFRADYERLRLLNPKNLTAEQ
                     LRAANPDFVASAVTSDFSRDGVGTRQELAELGVASYASAVDCPQFLPDTTPFDRLLVDY
                     DNYGKIFGVADRAAELTRRQRKVIADAQSASAARRTQPRVVYLYSVYNDGLPYVAGNSG
                     MPQDMSRILRAPNAFEDLGGDWAEVGWEEIAARNPSVIVLADLPDRGLRGDKAAQKIEI
                     LREHPVISQLTAVRENRFITVPGLELDPTVGSVNALREIKDGLQRLG"
     gene            complement(2585..3751)
                     /locus_tag="EV193_RS28775"
                     /old_locus_tag="EV193_113104"
     CDS             complement(2585..3751)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (30-380). E-value:
                     9.1e-45. Score: 145.2. Matches aSDomain:
                     nrpspksdomains_EV193_RS28775_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF005732.0"
                     /locus_tag="EV193_RS28775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_113104"
                     /product="aminotransferase"
                     /protein_id="WP_130348071.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 2.4e-44, bitscore:
                     145.1, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 5.7e-10,
                     bitscore: 32.1, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRFRSHTLEVEGSPITAVYAALRGHRPRRAQLDLAQAAPSYPPAP
                     VVREHIVRTARSTEGSAYTEVPGMPSLRAAYAAEINRDYGGAVTPDNVVITAGCNQAFC
                     LTISALAEPGSEVIVPLPYYFNHDMWLKLNGITPVYLEPDENLVPRAEAIEALVTDRTR
                     AVVLVTPGNPTGITVPPEEIRLFAMAARKRGIALVLDETYRSFRDVDDPAHRLFREPGW
                     LDTVVSLHSFSKELALPGYRVGAVVGSPELNQEIAKLLDCVAVCAPRIGQEAVLAGLRH
                     AREWRIERSRDIASRRSWFRQVMAQRPGGFEALSCGGFFAWIRHPFADRPTAQVVRELA
                     IRFDAIVMPGTAFLPCDHNMIRVSVGNCDRDAVDDLARRLEAFSRSIA"
     aSDomain        complement(2612..3661)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EV193_RS28775_Aminotran_1_2.1"
                     /evalue="9.10E-45"
                     /label="EV193_RS28775_Aminotran_1_2.1"
                     /locus_tag="EV193_RS28775"
                     /protein_end="380"
                     /protein_start="30"
                     /score="145.2"
                     /tool="antismash"
                     /translation="QLDLAQAAPSYPPAPVVREHIVRTARSTEGSAYTEVPGMPSLRAA
                     YAAEINRDYGGAVTPDNVVITAGCNQAFCLTISALAEPGSEVIVPLPYYFNHDMWLKLN
                     GITPVYLEPDENLVPRAEAIEALVTDRTRAVVLVTPGNPTGITVPPEEIRLFAMAARKR
                     GIALVLDETYRSFRDVDDPAHRLFREPGWLDTVVSLHSFSKELALPGYRVGAVVGSPEL
                     NQEIAKLLDCVAVCAPRIGQEAVLAGLRHAREWRIERSRDIASRRSWFRQVMAQRPGGF
                     EALSCGGFFAWIRHPFADRPTAQVVRELAIRFDAIVMPGTAFLPCDHNMIRVSVGNCDR
                     DAVDDLARRL"
     misc_feature    complement(3735..3750)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.6"
                     /tool="antismash"
     gene            complement(3795..4886)
                     /locus_tag="EV193_RS28780"
                     /old_locus_tag="EV193_113105"
     CDS             complement(3795..4886)
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (86-351). E-value: 2e-16.
                     Score: 52.0. Matches aSDomain:
                     nrpspksdomains_EV193_RS28780_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012382.4"
                     /locus_tag="EV193_RS28780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_113105"
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="WP_207222848.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 4.4e-16, bitscore:
                     52.1, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVAALTDINGGLNLTDGHARLALSNEQAEVIEQFPTLFHEASRR
                     RFADIETEAHRVFFDTIGQHTAPVGTGRILSCYSSTLATDIVARALPVGTKVALLHPTF
                     DNIADLFRTRGLSLTALSEADLMEQRWPSAVDVIAITHPNNPTGLVTPPDHLRSLAEHA
                     ARAGQTVIVDAAFRGQVRSAQYDTYAILDAAGVDWITFEDTGKLWPMHEMKIGMLVFSE
                     RHAAAIEAAFAESLLSASPAVLLLVRELARDWAAGGFESARALVERNRRIVSDEIGRVG
                     LELADPKSEISVARIQLPAGGPDSAKLYREMVGRGVHVLPCPPFHWANPEEGLRLIRVS
                     LARPSDAVEAAARTLASTFAELA"
     aSDomain        complement(3834..4628)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EV193_RS28780_Aminotran_1_2.1"
                     /evalue="2.00E-16"
                     /label="EV193_RS28780_Aminotran_1_2.1"
                     /locus_tag="EV193_RS28780"
                     /protein_end="351"
                     /protein_start="86"
                     /score="52.0"
                     /tool="antismash"
                     /translation="VARALPVGTKVALLHPTFDNIADLFRTRGLSLTALSEADLMEQRW
                     PSAVDVIAITHPNNPTGLVTPPDHLRSLAEHAARAGQTVIVDAAFRGQVRSAQYDTYAI
                     LDAAGVDWITFEDTGKLWPMHEMKIGMLVFSERHAAAIEAAFAESLLSASPAVLLLVRE
                     LARDWAAGGFESARALVERNRRIVSDEIGRVGLELADPKSEISVARIQLPAGGPDSAKL
                     YREMVGRGVHVLPCPPFHWANPEEGLRLIRVSLARPSDAVEAA"
     misc_feature    complement(4773..4775)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    4897..4913
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.95"
                     /tool="antismash"
     misc_feature    5000..5014
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.38"
                     /tool="antismash"
     gene            complement(5001..6026)
                     /locus_tag="EV193_RS28785"
                     /old_locus_tag="EV193_113106"
     CDS             complement(5001..6026)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /GO_process="GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     aminopolycarboxylic-acid: AesC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081: cysteine synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005153008.1"
                     /locus_tag="EV193_RS28785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_113106"
                     /product="cysteine synthase family protein"
                     /protein_id="WP_242613746.1"
                     /sec_met_domain="AesC (E-value: 3.5e-140, bitscore: 460.0,
                     seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="PALP (E-value: 1.8e-61, bitscore: 201.2,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYPGEMGAVIKNKISELIGSTPMLRLDGIEGAGNVILKLEQFNPT
                     GTAKIRMARQMVDEAEESGLLKAGGWLVESTSGNTGLGLAVIAAERGYRFSAVVDNHSS
                     MDKLRAMRAYGAELINVGGEDEALVTAERDATAEKLAIEHGAYWTEQHANPGNPNGYLA
                     LAEELHQALDDDLHFLYGAVGTGGSLCGAGRALRKRIPDLKIIGVEPVGSIAFGGVGAP
                     YYQSGTGSPEGSEIGDLVDYDLIDEGIKVSDSEAFETCRYLARNYGILVGGSAGGVIYK
                     ALEQAQSVDPSTNIVVLVCDGGEKYLDTVFDDDWMTSTGLHSTDVVEKLASMLGKKDRQ
                     N"
     misc_feature    complement(5982..5995)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.62"
                     /tool="antismash"
     misc_feature    complement(6049..6066)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 20.94"
                     /tool="antismash"
     gene            complement(6058..7248)
                     /gene="hisC"
                     /locus_tag="EV193_RS28790"
                     /old_locus_tag="EV193_113107"
     CDS             complement(6058..7248)
                     /EC_number="2.6.1.9"
                     /GO_function="GO:0004400 - histidinol-phosphate
                     transaminase activity [Evidence IEA]"
                     /GO_process="GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (47-378). E-value:
                     3.9e-57. Score: 185.9. Matches aSDomain:
                     nrpspksdomains_EV193_RS28790_Aminotran_1_2.1"
                     /codon_start=1
                     /gene="hisC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005153004.1"
                     /locus_tag="EV193_RS28790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_113107"
                     /product="histidinol-phosphate transaminase"
                     /protein_id="WP_242613747.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 9.7e-57, bitscore:
                     185.9, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQIEGQAERAGEHPSAMESLVRPEVAGLPAYDPGADPDEVSRSYG
                     PTRIIKLSNNESPYGVSAGVVEAVRRRLAAGVARYPDPMGKRLAEAIGDKLAVSTEHVI
                     LGNGSENILELLSPALLGAGDIVTIQAPCFSLHEIFPRMMGARVDKVPFTADFGFDTAG
                     WLRALAADPKIVFIASPSNPTGVILDREQLDTILDATPETALVVLDDAYHEYAMSNPSY
                     PDGLEVLRGLSRPWIVLRTFSKAYGLAGLRVGYGIASDARLVDALNRVRTPYNVNQVAQ
                     DAAVAALDDQAHLAETVRRTGLERTRITKALRAAGFRVAPSASNFLFIDTEQSAVVVAE
                     QLLRSGIIVKPWREPGYEGFIRASLSLPEENDVFVRRLLEICALGRSNGDRPSTYP"
     aSDomain        complement(6115..7107)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EV193_RS28790_Aminotran_1_2.1"
                     /evalue="3.90E-57"
                     /label="EV193_RS28790_Aminotran_1_2.1"
                     /locus_tag="EV193_RS28790"
                     /protein_end="378"
                     /protein_start="47"
                     /score="185.9"
                     /tool="antismash"
                     /translation="RIIKLSNNESPYGVSAGVVEAVRRRLAAGVARYPDPMGKRLAEAI
                     GDKLAVSTEHVILGNGSENILELLSPALLGAGDIVTIQAPCFSLHEIFPRMMGARVDKV
                     PFTADFGFDTAGWLRALAADPKIVFIASPSNPTGVILDREQLDTILDATPETALVVLDD
                     AYHEYAMSNPSYPDGLEVLRGLSRPWIVLRTFSKAYGLAGLRVGYGIASDARLVDALNR
                     VRTPYNVNQVAQDAAVAALDDQAHLAETVRRTGLERTRITKALRAAGFRVAPSASNFLF
                     IDTEQSAVVVAEQLLRSGIIVKPWREPGYEGFIRASLSLPEENDVFVRRL"
     gene            complement(7254..8666)
                     /locus_tag="EV193_RS28795"
                     /old_locus_tag="EV193_113108"
     CDS             complement(7254..8666)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1086: MATE efflux
                     family protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:TIGR00797.1"
                     /locus_tag="EV193_RS28795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_113108"
                     /product="MATE family efflux transporter"
                     /protein_id="WP_207222849.1"
                     /transl_table=11
                     /translation="MIKSSGGTTAGWWIVNSRSLLALAFPLILTNFAHVALTTVDIVML
                     GRLGATEIAAAGLAIVLFNQLRTMGTGLVTGVSNLVAEAHVRNDVQRIRDLLVAGFFWA
                     TVSGIVFAVVLLLIGPVLLWLGQEPEVVEKSGQFLTVLAPGMVPCLWFQTLRHFTTGLK
                     RPGPLLAITLVSIAATIGLNYVLIYGKLGLPAFGFVGVAIATTTVFTLSFLMFLLVIVK
                     NRSFSPYLSRSELRWSGDAVKSVWKLGLPISGTYASEAGFFSVLTLLIGTLGTEALAAQ
                     TLLNQIIYIVFMISAGFSHAASVHISEAHGVGDYVKARRLGILGLALGVLAMLVVAIPY
                     LVVPDAIVSLFLSADHEGNAAILALTASGLLIATVLQVFDASQNIGNGILRGVGDAVGP
                     FRISLVGYWLVGLPVSYLLGVAAGQGVQGVWVGQTIGLATTAGMLVVAFLVRVNRLKQK
                     ASDTVALESSKS"
     gene            complement(8663..9661)
                     /locus_tag="EV193_RS28800"
                     /old_locus_tag="EV193_113109"
     CDS             complement(8663..9661)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     aminopolycarboxylic-acid: AesA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1158: ornithine cyclodeaminase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005153002.1"
                     /locus_tag="EV193_RS28800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_113109"
                     /product="ornithine cyclodeaminase"
                     /protein_id="WP_130348074.1"
                     /sec_met_domain="AesA (E-value: 1.3e-104, bitscore: 342.4,
                     seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNQPAGYASPGELWLLPQSELEDLEISYPQVLKIVEQAYKAVRNG
                     GSRNPVKTIVEGADERSLSYSMVALDGDSDTVCFKAVYEFDPQRTRDSYGFHSFIFLCD
                     DTTGRPIALMDVVKLGPLRSSATSALMARAVCPDARSALVMGTGVQGQMALPMLLAALP
                     NLERLRVYGTYEEGLRAVRKSVTDSHPDRDVEFVDDVPKAAAEADIVLGVSGLSAKQEV
                     RRDWMKPGAIAVLLGYGVHADVLHGSEYRIATDAEQMRATCDDLRAEDGSLPPVDAELP
                     DILLGHTPARKDATDVVFAYNSGMAVTDAALGRYVADLALTAGRGSRVRFW"
     gene            complement(9694..11076)
                     /locus_tag="EV193_RS28805"
                     /old_locus_tag="EV193_113110"
     CDS             complement(9694..11076)
                     /EC_number="5.1.1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     aminopolycarboxylic-acid: AesB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_Arg_deC_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1264: diaminopimelate decarboxylase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005153000.1"
                     /locus_tag="EV193_RS28805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_113110"
                     /product="alanine racemase"
                     /protein_id="WP_207222850.1"
                     /sec_met_domain="AesB (E-value: 6.8e-150, bitscore: 492.2,
                     seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Orn_Arg_deC_N (E-value: 9.3e-24, bitscore:
                     77.3, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMFDQGGASTKPFPLTALRHPGVSHLLSKQADLLADLANGLGSPL
                     HVLLPEIFEENVRRMRGTVAELGIDAGILFAKKANKADCFVRSSARLGIGIDVASAPEL
                     AKALAGGIPGERIGISGPEKDSALHSVALQHGCLVAIDSLSELRRLSESARGMRKPARV
                     LLRCRVDAQSRSRFGMAAAERNEAVSLCADAPESVRLEGFSFHLTGYSTQERAHAANEM
                     IEHCVVARARGLAHCRLVDIGGGLPLRYVDPATWDGFLRQDAPDHYHMGKSFDGFYPYG
                     TERPADLALRDIMKHPVDADETLMSKASRNDIGFLVEPGRALLDQAGFTIFGVQQVDDR
                     RESDGYAIVTVHGSSFSLSEQWFNSEYLPDPVLIASEPVGNREFHASVAGSTCLESDML
                     TWRKIGFPRVVEPGDQLVYLNTAGYQMDSNESPFHEMPIPQKVVVRLGEEGNQPKWRLD
                     GI"
     misc_feature    11225..11241
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 19.45"
                     /tool="antismash"
     misc_feature    complement(11269..11278)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.85"
                     /tool="antismash"
     misc_feature    complement(11274..11288)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.54"
                     /tool="antismash"
     misc_feature    complement(11339..11352)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 16.34"
                     /tool="antismash"
     gene            11654..12472
                     /locus_tag="EV193_RS28810"
                     /old_locus_tag="EV193_113111"
     CDS             11654..12472
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009945441.1"
                     /locus_tag="EV193_RS28810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_113111"
                     /product="serine protease"
                     /protein_id="WP_242613748.1"
                     /transl_table=11
                     /translation="MAKSLRRVATAIGALAGIGALAIGFAPISNAQPSQPAGPLIVGGS
                     PADIKDFPSTVALHRDGGAWCGGTVAAPTKVITAAHCLKGFENSKWTVITGRTNVKDTS
                     TGAEVNVKSFWLHPNYKDVTQGDDVAVLTLEKAVEAPAVKFAKAGDEKLYAPGTTSTVV
                     GWGRTKEGGQGSDSLLKVDVPVVADDTCAASYQEYDKNSMVCAGFPEGGKDSCQGDSGG
                     PQYVNGTLIGIVSWGEGCARPDKYGLYTRVITYAGEIQKQLDATGTPARR"
     gene            complement(12540..12866)
                     /locus_tag="EV193_RS28815"
                     /old_locus_tag="EV193_113112"
     CDS             complement(12540..12866)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005440914.1"
                     /locus_tag="EV193_RS28815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_113112"
                     /product="putative quinol monooxygenase"
                     /protein_id="WP_130348075.1"
                     /transl_table=11
                     /translation="MIFITAKFRVLPEHADNWPEISREFTEATRAEPGCLWYDWARSVD
                     DPNEYVLTEAFRDDDAGAAHVQSDHFKTAQSTLPPYLAETPRIVNFTIPQDDWSLLGEL
                     AVER"
     gene            complement(12863..13870)
                     /locus_tag="EV193_RS28820"
                     /old_locus_tag="EV193_113113"
     CDS             complement(12863..13870)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009944847.1"
                     /locus_tag="EV193_RS28820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_113113"
                     /product="aldose 1-epimerase family protein"
                     /protein_id="WP_130348076.1"
                     /transl_table=11
                     /translation="MRLSRRTAIGGALAAGAAMTVGGTASAQPGERHTASGRVYELRHG
                     DQHAVIAGVAATLLSYRAGGEELLLTHPADEMGEGYQGKTILPWPNRIDHGRYTFGGVE
                     HQVPINEIERDTALHGLLSFTEWEPVRHERDHVVLRIRQYPHYGYPFELAFQIEFSLGP
                     DGLRSTLTARNTGDSPAPFGTANHTYVRAASGTIDSMELELGADTHYLVNDRLIPTGTA
                     PVAGTPYDFRTRRRIGDTLMDTAFTGLRRNARGVASVHFGRPGGRNVEMWMDRGYGYLQ
                     VYTDDGPDGHPPRSGITVEPVSCAPNCFNTGDGLVVLEPGERWRGSFGYRTMGA"
     gene            complement(13867..15621)
                     /locus_tag="EV193_RS28825"
                     /old_locus_tag="EV193_113114"
     CDS             complement(13867..15621)
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007031641.1"
                     /locus_tag="EV193_RS28825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_113114"
                     /product="sugar-binding domain-containing protein"
                     /protein_id="WP_207222851.1"
                     /transl_table=11
                     /translation="MTTPAHAEPAAPALTTPWTSQVNPDNALPEYPRPQLTRPKWQNLN
                     GLWEYTTRGQKRPDRYGEQILVPYPPESALSGIGRHDDRMWYRRTFEVPPDWRGQRVLL
                     HFGAVDQVATVWVNNQQVATHEGGYTAFSADVTDALRAGGPQEIVVRAEDRNEINTYPV
                     GKQRNDPGGILYTGASGIWQTVWLEPVPAAHVSTVDITPELTGFSVTPRVSGATGERAE
                     VIVRAPGGAEVARAQGEPGRPIWLAVPDPHLWTPEDPYLYDITVRLLDQTGKAGDEVGG
                     YAGLRTVSTVRDAAGRPRIAVNGKITFLHGPLDQGYWPDGIYTAPTDDALRFDLEKTKE
                     LGFNFVRKHVKVEPARWYYWADRLGLLVWQDMPSLPVLLDNPPGPQAPPVPEAQRHFET
                     ELDAMINQLRSVTSIIGWVPFNEGWGEYDTARIAAHVKALDPTRHVNANSGVNCCHSHP
                     DSGAGDVYDDHTYVGPGRPVVKDARSIVDGEYGGLGLVVDGHVWPGRPQAYEMTDSPEQ
                     LTRRYVEVSEDLVKVIESNGLSGAIYTQTTDVENEVNGFLTYDRRVMKPDLSVVAQHNR
                     AAIEAGTP"
ORIGIN
        1 acggcgacgg cgccggtcga cgcgccggag gacacgccga gcaggtaagg atccgccaac
       61 gggttccggg tgaccgactg caggacggcg cccgcgacgg tcagcgccat tccgaccgcg
      121 cccgccagca ggacacgcgg cacacgcgac tcccagatca gggcgtccag cagcctcggc
      181 aacggctcgg tcggggcgat cgcacccaat ccgacatgtc gcagaatcgt ggaaatgacg
      241 tcgagcgggc cgatgttcgc ggttccgaac aacgtcgcgg aaacgatcgt cacgaacaac
      301 gcggcggtgg ccagagcgcc aagagccatc ggtggaatac gccagggccg tctcgctccc
      361 gatccgagac tcgcgggcgg tcccgcggcc cgctcggtgg gcgggatctg tgcggtcacg
      421 gcgccgctgg accgctcatt cgaggtcaac gaagccctcg ctgaacgagt tcgacgagcc
      481 ctttggcgag tgcgggaacc gcgtaggcgc tgccatagct cggatccatg tagcgcccag
      541 gaataatgac gaaccgatca ttcgccacgg cttcgagctt gctggtgagc ggatctttct
      601 tgagaaggtc gattttctcc ttcgccgtgt caccaggctc tcctcgggtg agatcggcga
      661 tgacgatgac gtccgggtca cgggccgcga cgctgtccca actcacctcg ggccactttg
      721 tcgacgcgtc gtcgaagacg ttcttcaccc cgaccatctc ggacacgtgc tggggcaacc
      781 cgccggtacc ggcggcccag ggcttaccgc cgaatgtgga gtaaaaccac atcacggtca
      841 gcgggtcctt ggccgccttg attcctttcg ccgtctcaag gccgctgttg atcacggcct
      901 gctgctcggc gatcagcttg ttgccggcgg cgggaacgtc gaaaatcctg gccaggttgc
      961 ggtattcgtc gaagagcaat tcgaaccggg cacctgccac ggactggtga tagacgcagt
     1021 cgaactcggt gagataggtc gggacgccca agccgtgcag gacatcgcgc tccccggact
     1081 gagccggggt gaagaagctc gcgaaggaag cgtaggcgaa atcgggctgc gcctgcaaca
     1141 gggcctcgtg cttgatttcc tgcccgtgcg cggaaagttt cgggatcttc tggtactcgc
     1201 cggcgatctc gggcggaatc tggtctatct catacccagt cccgacgatc ctgccgccca
     1261 ccccgagatg gatgaggatc tccgccgcgg cctggttcat cgtcaccact cgtcgagggg
     1321 tggccccgta agtcaccttt ttgccgcagt tctccactgt aagcgggtac ttcgtcaccc
     1381 cctcaccagc cgataccggc cgcgctccgg cgtcgttcga cgcggcaccg catccagcca
     1441 ggaccgcacc cacggacagc gccgcgagca cggcggcgat cttgcgcaag gtcatggcca
     1501 tacccctcga tctcgtctaa cgagaatgac aatcattact atcttagaga gggacgcagc
     1561 cgaggcaagg ggcaggcgcg gtcagcccag ccgctgaaga ccgtccttga tctcccggag
     1621 cgcgttcacg ctgcccacgg tgggatcgag ttcgagcccc ggcaccgtga tgaagcggtt
     1681 ctcgcggacg gccgtcagtt gcgatatcac gggatgctcg cgcaagatct cgatcttctg
     1741 ggccgccttg tcaccgcgga gaccgcgatc gggcaggtcc gccagcacga tgaccgatgg
     1801 attgcgtgcg gcgatctcct cccaaccgac ctccgcccag tctccgccga ggtcctcgaa
     1861 agcgttgggc gcccgcagaa ttcggctcat gtcctggggc atcccgctgt tgccggccac
     1921 atacggcagc ccgtcgttgt acaccgagta gaggtatacg acgcgcggct gggttcgccg
     1981 cgccgcactg gcggactgcg cgtccgcgat gaccttccgc tgtcgacggg tcagctccgc
     2041 cgcacggtcc gcgacgccga agatcttccc gtagttgtcg taatcgacga ggagccggtc
     2101 gaacggcgtg gtgtcgggca agaattgtgg gcagtccacc gcactcgcgt acgacgcgac
     2161 gcccaactcc gccagttcct gccgagtccc cacaccgtct cggctgaagt ccgaggtcac
     2221 cgcgctggcc acgaaatcgg gattcgccgc gcgcagttgc tcggcggtga ggttcttcgg
     2281 gttgagcagc cggagtcgtt cgtagtcggc ccgaaactcc ggtgcgaccg gccctatctg
     2341 caacgcggtt cccgcgattc gatctcgcaa accgagcgcc agcaggatct ccgtggtctc
     2401 ctgatccgcg gcgaccgcgc gcgccggcgg gtgttcgaca cgaatactcg tcccgcaatt
     2461 ctcgatgagc acgccgccgc gcgcttccgc ctgattggta tccacgcagc cggccgtcgc
     2521 gacgaccaga gcgagcacgg gcaccagggc gaaaccgcga cgggacactg cgactcccct
     2581 ttggctaggc gatcgaccgt gaaaacgctt cgagtcgccg cgcgagatca tccacggcat
     2641 cccggtcgca attgccgacg ctcacccgga tcatgttgtg gtcgcacggc aggaacgcgg
     2701 ttcccggcat gacgatggcg tcgaatcgaa tcgccagctc gcggacgacc tgcgcggtcg
     2761 gccggtcggc gaaagggtgc cgaatccacg cgaagaagcc accacaggac agcgcctcga
     2821 atccgcccgg ccgctgggcc atgacctgcc tgaaccagga tcggcgcgac gcgatgtccc
     2881 gagatctctc gatccgccat tcccgtgcgt ggcgcaaccc cgccaacacc gcttcctgac
     2941 ctattcgcgg agcgcacacg gcgacacaat cgagcagctt cgcgatctcc tggttgagct
     3001 ccggcgaacc gacgaccgcc cccacccgat aaccgggcaa cgccagctcc ttggagaacg
     3061 aatgcagact aaccaccgtg tcgagccatc ccggctcacg gaagagccgg tgggccggat
     3121 catcgacgtc ccgaaaggac cggtacgtct cgtccagcac gagtgcgatt ccccgtttcc
     3181 tcgcggccat ggcgaacagc cggatctcct cgggcggcac cgtgattccc gtgggattgc
     3241 ccggcgtcac caggacgacg gccctggtcc gatcggtgac cagcgcctcg atcgcctccg
     3301 cacgcggcac caggttttcg tcgggctcca ggtacaccgg ggtgattccg ttgagcttga
     3361 gccacatgtc gtggttgaag tagtacggca acggcacgat gacctcgctc cccggctcgg
     3421 ccaacgcgct gatcgtcaga cagaaagcct ggttgcatcc cgccgtgatg acgacattgt
     3481 caggggtgac cgctccgccg tagtcgcgat tgatctcggc ggcgtaggcc gcccgcagcg
     3541 acggcatacc cggcacctcg gtgtacgcac tcccctccgt actccgtgcc gtgcgaacga
     3601 tgtgctcgcg caccacgggc gcgggcggat acgacggtgc cgcctgagcg agatcgagtt
     3661 gggctcttcg gggtcggtga ccccgaagag ccgcatacac cgccgtaatg ggcgagccct
     3721 cgacctcgag cgtgtgtgaa cggaatcgca acggtctttc cgctcctcac tcgatggacc
     3781 ggcgagccgg acggctacgc caattctgcg aaagtactgg ccagcgtgcg agccgcggcc
     3841 tcgaccgcgt cggacggccg ggcgagcgac acccgaatca atcgcaggcc ctcctccgga
     3901 ttcgcccagt ggaacggtgg gcacgggagc acgtgcactc ccctgccgac catctctcga
     3961 tacaacttcg ccgagtccgg gccgcccgcc gggagctgaa tacgcgcgac actgatctcc
     4021 gacttcgggt cggccaattc gaggccgacc ctgccgatct cgtcggagac gattcgccga
     4081 ttccgttcga cgagcgcgcg agcgctctcg aatccgccag ccgcccagtc tcgcgcgagt
     4141 tctcgcacca gcagcagaac ggccggcgac gccgacaaca gcgactcggc gaaagccgct
     4201 tcgatcgccg ccgcgtgcct ctcggagaac acgagcatgc cgatcttcat ctcgtgcatc
     4261 ggccacaact tgccggtgtc ctcgaaggtg atccaatcga ccccggcggc gtcgaggatc
     4321 gcgtacgtgt cgtactgcgc cgatcgcacc tgcccgcgga acgccgcgtc gacgatcacg
     4381 gtctgtcccg cacgggcggc gtgttcggcc agtgagcgga gatgatccgg cggcgtgacc
     4441 aggccggtcg gattgttcgg atgggtaatc gcgatgacgt cgaccgccga cggccaccgc
     4501 tgctccatca ggtcggcctc ggacagcgcc gtcaacgaca gcccgcgggt ccggaacaga
     4561 tccgcgatgt tgtcgaacgt cggatgcagc agcgcgacct tcgtaccgac cggcagtgcc
     4621 ctggcgacga tgtccgttgc cagcgtcgac gagtaacagc tcaggatccg cccggtgccg
     4681 accggcgccg tgtgctggcc gatcgtgtcg aagaaaacac gatgagcctc ggtctcgatg
     4741 tccgcgaacc ggcgccggga cgcttcgtgg aataaggtcg ggaattgctc gatgacctcc
     4801 gcctgctcat tgctcagcgc gagccgcgca tggccatcgg tgaggttgag gccgccattg
     4861 atatcggtga gagcggcaac ctccatcttc gtaaggttgt caattttcat catgctgaca
     4921 cacttccact tcaatagcag aaattgatat gccgaaccgg caatcgcacc gcccttaccc
     4981 cccgactgca gaattcccgg tcagttctgt cgatctttct tgcccagcat ggacgccaac
     5041 ttctccacca cgtccgtgct gtgcagtccg gtggacgtca tccagtcgtc gtcgaagacc
     5101 gtgtccagat acttctcgcc gccgtcgcag accaggacga cgatgttggt cgagggatcc
     5161 accgactgtg cctgttcgag cgccttgtag atcacaccgc cggccgagcc gcccacgaga
     5221 atcccgtagt tgcgtgccag gtagcgacac gtctcgaatg cctccgagtc gctgaccttg
     5281 atgccctcgt cgatcaggtc gtagtcgacc agatcgccga tttccgatcc ctccggtgac
     5341 cccgtcccgg actggtagta cggcgcgccg acccctccga acgcgatgga cccgaccggc
     5401 tcgacaccga tgatcttgag atccggaatg cgtttccgaa gagcgcgccc ggccccgcac
     5461 agggagcctc cggtgcccac cgcgccgtag agaaaatgga gatcgtcgtc gagcgcctgg
     5521 tgcagttcct cggcgagcgc caggtagccg ttcggattcc cgggattggc atgctgctcg
     5581 gtccagtagg cgccgtgctc gatggcgagc ttctcggcgg tggcatcgcg ttccgcggtg
     5641 accagggcct cgtcctcgcc gccgacgttg atcagctccg ctccgtacgc ccgcatcgca
     5701 cgcagcttgt ccatactcga atgattgtcc acgaccgcgc tgaaccgata tccacgttcg
     5761 gccgcgatga ccgcgaggcc gaggccggta ttgccggacg tcgattcgac gagccaccct
     5821 ccggccttga ggagccccga ctcctccgcc tcgtccacca tctggcgggc catgcggatt
     5881 ttcgcggtcc cggtggggtt gaactgctcg agcttcaata tgacattgcc agctccctcg
     5941 atgccgtcca atctgagcat tggcgtgctg ccgatcagtt cagaaatctt gttctttatc
     6001 acggccccca tctcccctgg atacatgtgg tgcccgcccc tgagcccgca tcccctgtca
     6061 gggatacgtc gacggccgat cgccgttgga ccggccgagt gcacagattt cgagcagtct
     6121 gcgcacgaag acatcgttct cctccggcaa ggaaagcgac gcccgaataa agccctcgta
     6181 gcccggctct cgccatggtt tgacgatgat tcccgatcgg agcaactgct cggccacgac
     6241 gacagcggat tgttccgtgt cgatgaacag aaaattggat gccgacggcg cgacccggaa
     6301 gccggcggcg cggagtgctt tcgtgattct cgtgcgctcc agtccggtcc gccggacggt
     6361 ttcggccaga tgcgcctgat cgtccagtgc cgcgacggcg gcgtcctgag cgacctgatt
     6421 gacgttgtac ggagtacgca cccggttgag cgcgtcgacc aatctcgcgt cggacgcgat
     6481 gccgtatccc acccgaagtc cggcgaggcc gtacgctttc gagaacgttc tcagcacgat
     6541 ccacggacgg ctcagcccgc gcagcacctc gaggccgtcg ggatacgacg gattcgacat
     6601 cgcgtattcg tggtacgcgt cgtccaggac caccaacgcc gtctccggcg tcgcgtccag
     6661 aatggtgtcc aactgctccc ggtcgagaat caccccggtc gggttggacg gactcgcgat
     6721 gaagacgatc ttcggatctg ccgccaacgc ccgcagccac ccggcggtgt cgaagccgaa
     6781 atcagcggtg aacggaacct tgtcgacgcg cgcccccatc atgcgcggaa atatctcgtg
     6841 caggctgaaa cacggcgcct gaatggtcac gatgtcgccg gcgccgagga gcgccggact
     6901 gagcagctcg agaatgttct ccgagccgtt cccgaggatg acgtgctcgg tcgacaccgc
     6961 cagcttgtcg ccgatcgcct cggcaagacg tttgcccatg gggtccggat accgcgcgac
     7021 gcccgccgcc agtcgccgcc gcacggcttc cacgactccc gccgagacgc cgtaagggct
     7081 ctcgttgttg gagagcttga tgatgcgtgt cgggccgtag ctgcgcgaca cctcgtcggg
     7141 gtcggcaccg gggtcgtagg ccgggagacc ggcgacctcg ggccgaacca gtgattccat
     7201 cgcggaagga tgctctccgg ctctttccgc ctgcccctcg atctgcacct gtctcatgat
     7261 ttgctcgatt ccagcgcgac ggtgtccgaa gccttctgct tcaaacggtt gacgcgtacc
     7321 aggaatgcga cgacgagcat tcccgccgtg gtggcaagcc cgatggtctg ccccacccaa
     7381 accccttgaa caccctgccc cgccgccact ccgagcaggt aactgaccgg caatcccacg
     7441 agccagtaac cgacgagcga gattcgaaac ggcccgacgg cgtctccgac accgcggagg
     7501 atgccgtttc cgatgttctg gctggcatcg aatacctgca gcacggtcgc gatcagcaga
     7561 cctgaggcgg tcaaggccag aatggccgcg ttgccctcgt ggtcggcgga aaggaacagc
     7621 gacacgatgg catccggcac caccaggtag ggaatggcga caaccagcat cgccagcacg
     7681 ccgagcgcca gacccaggat gcccagccgc cgtgccttca cgtagtcgcc gacgccgtgc
     7741 gcctcgctga tgtgcacgga cgcggcgtgc gagaatcccg cggagatcat gaacacgatg
     7801 tagatgatct ggttgagcag ggtctgcgcc gcgagagctt ccgttcccag tgttccgatc
     7861 agcagcgtca ggacgctgaa gaacccggcc tcggaggcgt acgttcccga tatcggtagg
     7921 ccgagtttcc acaccgactt cacggcgtcc cccgaccagc gaagttccga tcgggaaagg
     7981 taggggctga aactccgatt cttgacgatc acgagcagga acatcaggaa cgagagggtg
     8041 aacacggtgg tggtcgcgat cgccacgccg acgaaaccga acgcggggag cccgagcttg
     8101 ccgtagatca gcacgtagtt caggccgatc gtcgcggcga tcgataccag cgtgatggcc
     8161 agcagcggac cgggacgctt gaggccggtg gtgaagtgcc gcaatgtctg gaaccacagg
     8221 caaggcacca tcccgggagc caataccgtg aggaactggc cgctcttctc caccacctcg
     8281 ggctcctgcc ccagccacag gagaaccgga ccgatcagca gcagcaccac ggcgaaaacg
     8341 attccgctga ccgtcgccca gaagaatccg gcgaccaaca gatcacgaat acgctggacg
     8401 tcgtttcgga cgtgcgcctc ggccaccaga ttgctcacgc cggtgaccag ccccgtgccc
     8461 atcgtgcgca actggttgaa caggacgatg gcgagacccg ctgcggcgat ctcggtggca
     8521 ccgagccggc cgagcatcac gatgtccacg gtggtgagcg cgacgtgggc gaagttggtc
     8581 agaatcagcg gaaaggcgag cgcgagaaga gacctcgaat tgacgatcca ccaaccggcc
     8641 gtcgtgccgc cactcgactt gatcaccaga accgtaccct cgatccacgt ccggccgtga
     8701 gcgccagatc cgccacatat cgcccgagtg ccgcgtccgt gaccgccatt ccgctgttgt
     8761 aggcgaaaac gacgtccgtg gcgtcctttc tggccggggt gtgccccaaa aggatgtccg
     8821 gcaactccgc gtcgaccggc ggcagactgc cgtcctcggc gcgcaggtcg tcgcaggtgg
     8881 cgcgcatttg ttcggcgtcg gtcgcgattc ggtattcgga cccgtggagc acatccgcgt
     8941 gcacgccata gccgagcagg acggcgatcg cacccggctt catccagtcg cgtcgcacct
     9001 cctgcttcgc ggacaggccg gacacgccga gcacgatgtc cgcttccgcg gcggccttgg
     9061 gcacgtcgtc gacgaattcg acatcgcgat caggatggct gtccgtgacg ctctttcgga
     9121 cggctcgcaa cccctcctcg taggttccgt agaccctcag ccgctccaga ttgggcaagg
     9181 ccgccagcag catcggcagc gccatctgcc cctggactcc ggtgcccatg accaacgcgc
     9241 tccgcgcgtc cggacacacc gcgcgcgcca tgagcgccga cgtggcagag gatcggagcg
     9301 gccccagctt gacgacgtcc atcaacgcga tcggcctgcc ggtggtgtcg tcgcagagaa
     9361 agatgaacga gtggaagccg tagctgtcac gggtgcgctg cggatcgaac tcgtagacgg
     9421 ccttgaagca gacggtgtcg ctgtctccgt ccagggcgac catcgagtag ctgagtgacc
     9481 gctcgtccgc accctcgacg atggtcttga cggggtttct cgagccgccg tttcgcaccg
     9541 ccttgtacgc ctgctcgacg atcttgagca cctgcgggta gctgatttcc agatcctcga
     9601 gctcggactg gggcaacagc cacagctctc ctggcgacgc atagcctgcc ggctgattca
     9661 tgctgtccaa catctccttc ggtcggtgct ggctcaaata ccgtccagac gccatttcgg
     9721 ctgattccct tcttcaccga gccgcacgac caccttctgc ggtatcggca tctcgtggaa
     9781 gggcgactcg ttggaatcca tctgatatcc ggcggtgttc aggtagacga gctgatcgcc
     9841 gggctcgacg acccgaggaa atccgatctt gcgccacgtc agcatgtcgc tttccaggca
     9901 cgtcgatccc gcgacactgg cgtggaattc gcggttgccc accggctcgg acgcgatcag
     9961 taccggatcc ggcaggtact cgctgttgaa ccactgctcg gacaggctga aactactgcc
    10021 gtggaccgtg acgatggcgt atccgtcact ttcccgccgg tcgtccacct gctgcacgcc
    10081 aaatatggtg aaacccgcct ggtccagcaa tgcccggccg ggctcgacaa gaaatccgat
    10141 gtcattccga gacgccttgc tcatgagcgt ttcatcggca tccacgggat gtttcatgat
    10201 gtcccgcagg gccagatccg cgggccgttc cgtaccgtat ggatagaacc cgtcgaacga
    10261 tttgcccatg tggtaatgat ccggagcgtc ttgccgcagg aagccgtccc aggtcgccgg
    10321 gtcgacgtat cgcagcggca ggccgccgcc gatgtcgaca agccggcagt gcgccaggcc
    10381 ccgtgcccgc gccacgacgc aatgctcgat catctcgttc gccgcgtgcg cgcgttcctg
    10441 ggtggagtat ccagtgaggt ggaaggagaa cccttccagg cgaacggatt cgggtgcgtc
    10501 agcgcacagc gagacggcct cgttccgctc ggcggcggcc attccgaatc ggctccgact
    10561 ctgtgcgtcc acgcggcagc gcagcagcac tcgggcaggc tttcgcatgc cgcgcgccga
    10621 ttcgctcaac cgtcgcagct cggacaggga gtcgatcgcc accaggcatc cgtgttgaag
    10681 tgcgaccgag tgaagtgccg agtccttctc cggaccggag ataccgattc gctcccccgg
    10741 gatcccacca gcgagcgcct tggccaactc cggtgcgctc gcgacgtcga ttcctatgcc
    10801 gagccgagcg gacgacctga cgaagcaatc cgccttgttc gccttcttcg cgaagagtat
    10861 tccggcgtcg atgccgagct cggcgaccgt gccccgcatg cgcctgacat tctcttcgaa
    10921 gatctccggc agcagtacgt gcagcggtga gccaagaccg ttggccaaat cggccagcag
    10981 atccgcctgc ttgctcagca ggtgcgaaac gccgggatgc cgaagagccg tcaaaggaaa
    11041 tggcttcgtc gaagcgccgc cctggtcaaa catcatgagc acccttcccg actggtgaat
    11101 agatgccatt caacgacagc cagccgcacc tggccaaaga tggttctcat caattcgctg
    11161 cgccccagca gcagctaccc cagaagtgcg gcccaagtgc cccagtagtg cgccacactc
    11221 aacctagcaa cgttgttaca acgagattag cccgactttt caaggctgtc aaaatatatc
    11281 tgaaatatat ctgaatgcac atatcgccac gtcgcaatat gtttacctta attgatcttc
    11341 atattggtta tacacgtgac aggcaatatg agcaatcaat tcggcatatg gcctacgccg
    11401 gccggacacc gctcgacgct ccacggtggc gcttgtccgc caggttcgga agccgccctg
    11461 gcctcgacca cccggaacca acgcctccgc acgccgtcga ggacgaagaa tctgtttcag
    11521 atcccccacc ctgacgtaag ggttgccgtc gaatcccgcc gtgcgggatt aattgcgact
    11581 ttcgtcgctg tcaacggtcg cgttcggatg cttggctcac ggggtcattt ccactcgatt
    11641 gaagggagct accgtggcga aatccctgcg ccgcgtcgcg accgcgatcg gtgccctggc
    11701 gggcatcggc gccctcgcga tcggcttcgc cccgatctcc aacgctcaac cgtcccagcc
    11761 cgccggcccg ctgatcgtcg gcggatcacc ggccgacatc aaggacttcc cgtccaccgt
    11821 ggcgctgcac cgcgacggcg gggcctggtg cggcggcacg gtcgccgcac cgaccaaggt
    11881 gatcaccgcg gcccactgcc tcaagggctt cgagaacagc aagtggaccg tgatcaccgg
    11941 ccgcaccaac gtcaaggaca cctcgaccgg tgccgaggtg aacgtcaagt cgttctggtt
    12001 gcaccccaac tacaaggacg tcacccaggg cgacgacgtc gcggtgctga ccctggagaa
    12061 ggcggtcgag gcgccggcgg tcaagttcgc caaggccggc gacgagaagc tgtacgcgcc
    12121 gggcaccacg agcaccgtgg tcggctgggg ccgcaccaag gagggtggcc agggctccga
    12181 ctccctgctc aaggtggacg tcccggtcgt ggcggacgac acctgtgccg cctcttacca
    12241 ggagtacgac aagaactcga tggtctgcgc cggattcccc gagggcggca aggactcctg
    12301 ccagggtgac tccggcgggc cgcagtacgt caacggcacg ctgatcggca tcgtctcctg
    12361 gggcgagggt tgcgcccggc cggacaagta cggcctgtac acccgggtga tcacctacgc
    12421 cggtgagatc cagaagcaac tcgacgcaac gggcaccccc gcacgccggt agttcttccg
    12481 agggaggtgc cgcgtcggac acaactccgg cgcggcacct cttggcgcga cgggctgagt
    12541 cagcgctcga cggccaactc gccgagcagc gaccagtcgt cctggggaat cgtgaagttc
    12601 acgattcgcg gtgtctcggc gaggtagggc ggcagcgtgc tctgcgctgt cttgaaatgg
    12661 tccgactgga cgtgcgcggc accggcgtcg tcatcgcgga acgcctcggt cagcacgtac
    12721 tcgttggggt cgtcgacact gcgcgcccag tcgtaccaga gacaccccgg ctcggcgcgg
    12781 gtcgcctcgg tgaactcgcg gctgatctcg ggccagttgt cggcgtgctc cggcaggacg
    12841 cggaacttcg cggtaatgaa gatcatgcgc ccatcgtgcg gtagccgaac gagccgcgcc
    12901 agcgttcacc cggttcgagt acgaccagcc cgtcaccggt gttgaaacag ttcggcgcgc
    12961 agctcaccgg ttcgacggtg atacccgagc gcggcgggtg cccgtccggc ccgtcgtcgg
    13021 tatagacctg caggtagccg tagccgcggt ccatccacat ctccacgttc cggccacccg
    13081 ggcgtccgaa gtggacggac gccaccccgc gcgcgttacg gcgcaaaccg gtgaacgcgg
    13141 tgtccatgag ggtgtcgccg atccgccttc gcgtgcggaa gtcgtacggc gtgccggcga
    13201 ccggcgccgt gccggtcggg atgagccggt cgttcaccag gtagtgcgtg tccgcgccca
    13261 gctccagttc catcgagtcg atcgtgccgc tcgccgcccg gacgtaggtg tggttggccg
    13321 tgccgaaggg tgccggcgaa tcgcccgtgt tacgcgcggt cagggtgctg cgcaggccgt
    13381 ccggcccgag cgagaactcg atctggaagg ccagctcgaa cggatagccg tagtgcgggt
    13441 actgccggat ccgcagcacg acgtggtcgc gctcgtgccg caccggctcc cactcggtga
    13501 agctgagcag gccgtgcagc gccgtgtccc gctcgatctc gttgatcggc acctggtgct
    13561 cgaccccgcc gaacgtgtac cggccgtggt cgatgcggtt gggccacggc aggatcgtct
    13621 tgccctggta gccctcgccc atctcgtcgg cgggatgggt gagcagcagt tcctcgccgc
    13681 cggcccggta ggacagcagc gtggccgcga cgccggcgat caccgcgtgc tgatcaccgt
    13741 ggcgcagctc gtacacccgg ccgctggcgg tgtgacgctc acccggttgg gcgctcgccg
    13801 tgccgcccac cgtcatggcg gcaccggccg ccagtgctcc gccgatcgcc gtgcgcctgc
    13861 tcagtctcat ggtgtccccg cttcgatcgc cgcacgattg tgttgcgcca caacggaaag
    13921 gtccggcttc atcacccgcc ggtcataggt gaggaacccg ttcacctcgt tctccacatc
    13981 ggtggtctgg gtgtagatcg cgccggacag gccgttgctc tcgatcacct tgaccaggtc
    14041 ctcactgacc tcgacgtagc gccgggtcag ctgctccggg ctgtcggtca tctcgtaggc
    14101 ctgcggccga cccggccaca cgtgcccgtc caccaccagg ccgagcccgc cgtactcacc
    14161 gtccacaatg gaccgtgcgt ccttcaccac agggcggccg ggcccgacgt aggtgtggtc
    14221 gtcgtacacg tcgccggcac ccgagtcggg gtgtgagtgg cagcagttga cgccactgtt
    14281 ggcgttcacg tgccgggtcg ggtcgagcgc cttcacatgc gcggcgatcc gcgccgtgtc
    14341 gtactcgccc cagccctcgt tgaacggaac ccagccgatg atcgaggtga cactgcggag
    14401 ctggttgatc atggcgtcca gctcggtctc gaagtgccgc tgcgcctccg gcacgggcgg
    14461 cgcctgcggg ccgggcggat tgtccagcag cacgggcaac gacggcatgt cctgccacac
    14521 aagcaatccg agccgatcgg cccagtagta ccagcgcgcc ggttccacct tcacgtgctt
    14581 gcgcacgaag ttgaagccca gctccttggt cttctccagg tcgaagcgca gcgcgtcgtc
    14641 ggtcggcgcg gtgtagatcc cgtccggcca gtaaccctgg tcgagtgggc cgtgcaggaa
    14701 ggtgatcttg ccgttcaccg cgatcctcgg ccggccggcc gcgtcgcgca cggtcgacac
    14761 cgtgcgcagg ccggcgtagc cgccgacctc gtcgcccgcc ttgccggtct ggtcgagcag
    14821 ccgcacggtg atgtcgtaga ggtacgggtc ctccggcgtc cacaggtgcg gatcgggcac
    14881 ggccagccag atcggccgcc ccggctcgcc ctgcgcgcgg gccacctcgg cgccgcccgg
    14941 cgcgcgcacg atcacctcgg cacgctcgcc ggtcgcaccg gaaacccttg gtgtgacgga
    15001 gaatccggtc agctccggcg tgatgtccac tgtggacaca tgcgcggccg gcacgggctc
    15061 cagccacacc gtctgccaga tcccggacgc gccggtgtac aggatgccgc cggggtcgtt
    15121 gcgctgcttg ccgaccgggt aggtgttgat ctcgttgcgg tcctcggcgc gcaccacgat
    15181 ctcctgcggg ccgccggcac gcagcgcgtc ggtcacgtcg gcgctgaacg cggtgtagcc
    15241 accctcgtgc gtggcgacct gctggttgtt cacccatacg gtggccacct ggtccaccgc
    15301 gccgaagtgc agcagcacgc gctggccgcg ccagtccggc ggcacctcga acgtgcggcg
    15361 gtaccacatc cggtcgtcgt gccggccgat cccggacagc gcggactccg gcgggtacgg
    15421 cacgaggatc tgctcgccgt accgatcggg gcgcttctgg ccgcgggtcg tgtactccca
    15481 caggccgttc aggttctgcc acttcggacg ggtgagctgc gggcgcgggt actcgggcag
    15541 cgcgttgtcc gggttgacct gcgaggtcca cggcgtggtg agcgcgggcg cggccggctc
    15601 ggcgtgtgct ggtgtggtca tcgaaaccat gatcgcagcg agcaggggga cgacggctaa
    15661 ggacgcgatg cggaccatgt gtcccacacg accatgtggc cgagtcaccg tcatccgtcc
    15721 gttcgggtga acttcacaca cgctcggtca agatcacgcc aagtcttcac gggcagtgag
    15781 cgcggcgagt cgatcgacga cctcgtgcag cggcgcgcgg gtgtcgatct ccacggtggc
    15841 gaactcccgc agcagcggct cgacctcggc ggtgtcggcc gcgatcgcgg cgcgctgctc
    15901 ggcggtccgg ccgaacgggt tttcccgcgc ggcgacccgc tcgagcatga tctccagcgg
    15961 cgcggtcagc agcacgatct cggcgaacct cgggtagaac acgctctggt tccacaccgt
    16021 gccggcgacg aacagcggct cgcccgatcg ctcgtgcccg gtcagcagcg cgtcga
//
