LOCUS       NZ_SGWQ01000010        22503 bp    DNA     linear   CON 10-APR-2024
DEFINITION  Herbihabitans rhizosphaerae strain DSM 101727 Ga0310478_110, whole
            genome shotgun sequence.
ACCESSION   NZ_SGWQ01000010
VERSION     NZ_SGWQ01000010.1
KEYWORDS    WGS; RefSeq.
SOURCE      Herbihabitans rhizosphaerae
  ORGANISM  Herbihabitans rhizosphaerae
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Herbihabitans.
REFERENCE   1  (bases 1 to 269051)
  AUTHORS   Goeker,M.
  TITLE     Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing
            the most valuable type-strain genomes for metagenomic binning,
            comparative biology and taxonomic classification
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 269051)
  AUTHORS   Goeker,M., Huntemann,M., Clum,A., Pillay,M., Palaniappan,K.,
            Varghese,N., Mikhailova,N., Stamatis,D., Reddy,T., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-FEB-2019) Prokaryotic Super Group, DOE Joint Genome
            Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.12.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 226.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004216555.1-RS_2024_04_10
            Annotation Date                   :: 04/10/2024 19:27:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,690
            CDSs (total)                      :: 6,628
            Genes (coding)                    :: 6,561
            CDSs (with protein)               :: 6,561
            Genes (RNA)                       :: 62
            rRNAs                             :: 3, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2 (5S)
            tRNAs                             :: 54
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 13 of 67
            Pseudo Genes (incomplete)         :: 59 of 67
            Pseudo Genes (internal stop)      :: 5 of 67
            Pseudo Genes (multiple problems)  :: 9 of 67
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:31:17
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 116960
            Orig. end                         :: 139463
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            SGWQ01000010.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22503
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="2"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22503
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22503
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12503](+)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12503
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     gene            2..574
                     /locus_tag="EV193_RS25470"
                     /old_locus_tag="EV193_110113"
     CDS             2..574
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007030164.1"
                     /locus_tag="EV193_RS25470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_110113"
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_130347249.1"
                     /transl_table=11
                     /translation="MAEEMDEVLTAVGPRLRELRRRAGATLASLSEITGISVSTLSRLE
                     SGERKPSLELLLPLARVHRVPLDELVGAPETGDPRVHARPIRRDGRTYLPLTRRPGGVQ
                     AYKLILPPGEGEPDPRVHEGYEWFYVLNGRVRLVLGERETVLKPGEAAEFDTHVPHWFA
                     AADSRPAEILSLFGPQGERLHVRARTT"
     gene            complement(575..1327)
                     /locus_tag="EV193_RS25475"
                     /old_locus_tag="EV193_110114"
     CDS             complement(575..1327)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EV193_RS25475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EV193_110114"
                     /product="hypothetical protein"
                     /protein_id="WP_130347251.1"
                     /transl_table=11
                     /translation="MSKYEGIRRQVAEARDHAIAARFLAATAHEDVGDVQQQLRAHTGS
                     LNALRETQIDHGRDITAIRQIQIDHGRDITAIRQTQTEHGVEITTLRTVQIEHGLEIKA
                     LRQTQVEQGVDISALRETQVQQGVDISALRETQVQQGVDISALRETQIEQGVDISALRE
                     TQVQQGVDISALRETQVQQGVDISALRETQVQQGQTLVQHGAEIRSLRSEMREGFTQVH
                     GEMSDMRKGIERITALLTDKKGDGGTKP"
     misc_feature    complement(1408..1422)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.42"
                     /tool="antismash"
     gene            complement(1417..1620)
                     /locus_tag="EV193_RS25480"
                     /old_locus_tag="EV193_110115"
     CDS             complement(1417..1620)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016070.4"
                     /locus_tag="EV193_RS25480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_110115"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_130347253.1"
                     /transl_table=11
                     /translation="MTTPDHDRLTWRKSTYSANQTDCVELAWPAAGALFRDSKNPHVVM
                     AVEPVTVTALITSVKGPMPSCG"
     gene            complement(1631..2482)
                     /locus_tag="EV193_RS25485"
                     /old_locus_tag="EV193_110116"
     CDS             complement(1631..2482)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040183.3"
                     /locus_tag="EV193_RS25485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_110116"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_130347255.1"
                     /transl_table=11
                     /translation="MGDKESTVRMRELGLALRRALRERGLESKEVARRMRWSPSKISHI
                     LRATRGVSEADVSSLLTMCDIVGEERERLLELNRRAHEPGWLQEFGDRLPAELRTLIDH
                     EDAAAAINAYHGHLIPGLLQIPDYSRAIMAESVTIPPDEIDERIEARLHRQEILDRRRA
                     PLCRFFVDEYALSRTGPGPEIKSDQLHHLLRLSVRPRVVIRVIPDEVGFHAAIATPFVL
                     MEFTEINPVLHLENENTSVFPERKETVASYQKILARLDTVALDPEQSREWIASLASELG
                     AP"
     gene            2632..2913
                     /locus_tag="EV193_RS25490"
                     /old_locus_tag="EV193_110117"
     CDS             2632..2913
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EV193_RS25490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EV193_110117"
                     /product="hypothetical protein"
                     /protein_id="WP_130347257.1"
                     /transl_table=11
                     /translation="MLEHDQNLLVRFTKLANEVSTLDTRAARDLARELSQALGWTNASE
                     QACRMRRLALCMLDLALEFQDRAADLDRVIIDMPVGCPRGAIDRDRRA"
     gene            2882..3535
                     /locus_tag="EV193_RS25495"
                     /old_locus_tag="EV193_110118"
     CDS             2882..3535
                     /EC_number="2.7.4.9"
                     /GO_function="GO:0004798 - thymidylate kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013229736.1"
                     /locus_tag="EV193_RS25495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_110118"
                     /product="dTMP kinase"
                     /protein_id="WP_130347258.1"
                     /transl_table=11
                     /translation="MGRLIVIEGLDGAGKRTMSDGLTGALERRGARVVRRAFPRYDEDV
                     HAALIKDALHGRLGDLGESAHGMAVLFALDRLGAKEKLAADRASADVVLLDRYIASNAA
                     YLAARLRQSAAGEGVTWVRELEIDRFGIPVPDAQILLRVPSDVAAARAERRAREETDRE
                     RDTWESDGGLQARVEVVYEDLAAASWLSPWQVVDGLSTVDFDALTVTLLGGSPG"
     gene            complement(3541..3810)
                     /locus_tag="EV193_RS25500"
                     /old_locus_tag="EV193_110119"
     CDS             complement(3541..3810)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EV193_RS25500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EV193_110119"
                     /product="hypothetical protein"
                     /protein_id="WP_130347259.1"
                     /transl_table=11
                     /translation="MTSKTFAGVLAAVAVVGSVAFAAPASAATSNDVGPAGSTSGGWYK
                     DSDTCVNQGIWQVNNGWYDNFSCLYEPGGAPAPNVPWHLWLITN"
     gene            4229..>4339
                     /locus_tag="EV193_RS25505"
                     /pseudo=""
     CDS             4229..>4339
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015104936.1"
                     /locus_tag="EV193_RS25505"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="DNA-binding response regulator"
                     /pseudo=""
                     /transl_table=11
                     /translation="MASRVLVVDDDPALAEMLTIVLRGEGFDTAVVGDGSR"
     gene            4469..4969
                     /locus_tag="EV193_RS25510"
                     /old_locus_tag="EV193_110121"
     CDS             4469..4969
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014299.4"
                     /locus_tag="EV193_RS25510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_110121"
                     /product="hypothetical protein"
                     /protein_id="WP_165401503.1"
                     /transl_table=11
                     /translation="MSDGLTGALERRGARVVRRAFPRYTEDVHAALIKDALHGRLGESA
                     HGMAVLFALDRLGAKEKLAADLASADVLLLDRYIASNAAYLAARLRQSAAGEGVTWVRE
                     LEIDRFGIPVPDAQILLRVPSDVAGRRRTVHSRLRHPRGDSSRRLASPAVRVVHPFYDN
                     AAR"
     gene            5261..5908
                     /locus_tag="EV193_RS25515"
                     /old_locus_tag="EV193_110122"
     CDS             5261..5908
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012422.4"
                     /locus_tag="EV193_RS25515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_110122"
                     /product="response regulator transcription factor"
                     /protein_id="WP_130347261.1"
                     /transl_table=11
                     /translation="MALIEEDPLYRSAVRRVVEDAGAVTVVGEAASVDEFAAGQSSGGH
                     IDVAVIGMYDITACIAAVQALTDGGVTTNGSTPRGVLVMAPRYSDDALLSVLRAGARGY
                     VIKGGSHRELLLGLRVVADGGAMFGSAVAGRLGGYLAEPRDHDGQHPFPALTARERQVL
                     ELIAKGHSNRRIARALVLSEKTVRNHVTRLYRKLDVTDRIAAATRARDNGIS"
     gene            complement(5905..6576)
                     /locus_tag="EV193_RS25520"
                     /old_locus_tag="EV193_110123"
     CDS             complement(5905..6576)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015103337.1"
                     /locus_tag="EV193_RS25520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_110123"
                     /product="response regulator transcription factor"
                     /protein_id="WP_130347263.1"
                     /transl_table=11
                     /translation="MSDPIRVLVADDQALLRGSFRLLIDSEPGFTVVAEADNGRTAVDA
                     AREHKPDVVLMDVRMPEMDGIEATKALCDGEATSAVKVLILTMFDLDAYVFAALRAGAS
                     GFLLKDIPPADLLRAVSVVADGESLLAPAVTRRLITEFCRRPEPATVVPSELSGLTARE
                     REVLVLVAKGLSNPEIARHLHVSTATVKTHLAHLLDKLDARDRIQLVIIAYETGLISPA
                     R"
     gene            complement(6573..7760)
                     /locus_tag="EV193_RS25525"
                     /old_locus_tag="EV193_110124"
     CDS             complement(6573..7760)
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF019350.4"
                     /locus_tag="EV193_RS25525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_110124"
                     /product="sensor histidine kinase"
                     /protein_id="WP_207222801.1"
                     /transl_table=11
                     /translation="MVESARHQVFTRRLSRRELVVLDRIAAVTFTAVFFVISNYQQIGA
                     VPVPVRLGVAAIMGLPVAFRRRWPVPVLVVVAAASVLAAALGVLREPFLATAFALYLVG
                     ATVPASRWIPTSLIGLTSVIVLAGGLMVGSSSWQASTVATHVVGAALAGAAWTAGRAMH
                     ERRAYAARSVREVAASAVAEERLRIARELHDIVAHEVGLIAVKAGVANHVLARRPDEAS
                     AALRDIESASRSALAEMRNMLGVLRSEDEEAAADRRPGHGLERLPELVERASMAGVRVD
                     IDSRVGVHLPEGVDRSAYRIVQEALTNVIKHAAPTTCTVTVTDSGGKLCIDVVDGGAAG
                     HGPRRAPDRGGSTAGHGLIGMRERVALYGGTFDAGPSPDGGFAVSARLPFQRGDS"
     gene            7917..8837
                     /locus_tag="EV193_RS25530"
                     /old_locus_tag="EV193_110125"
     CDS             7917..8837
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007032351.1"
                     /locus_tag="EV193_RS25530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_110125"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_130347265.1"
                     /transl_table=11
                     /translation="MIEIRELTKRYGPAVAVDGLTFDVAPGRVTGFLGPNGAGKSTTMR
                     MLLGLDHPSGGRALLGGRPYRELREPLRIVGALLEARSTHGGRTAYHHLLWLAATNRIP
                     RRRVDEVLGLVGLESAAGKRAGTFSLGMSQRLGIAAALLGDPEIVLLDEPVNGLDPEGV
                     RWIRTLMKDLAAEGRTVLVSSHLMSEMAITADHLIVIGQGRLLADTTVDEFVAASRRGH
                     VRVSTPEADRLAALLDGRAVTVRRVDGALEITGMEAGAVGAVAGANGIALDELSTRSSS
                     LEDAFLELTAGSTEYSSRPQAEEVR"
     misc_feature    complement(7921..7933)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 16.72"
                     /tool="antismash"
     gene            8834..9610
                     /locus_tag="EV193_RS25535"
                     /old_locus_tag="EV193_110126"
     CDS             8834..9610
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024091.4"
                     /locus_tag="EV193_RS25535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_110126"
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_130347267.1"
                     /transl_table=11
                     /translation="MSVSNSPFAVLHGEWIKIRTVRSTLLSLAVAVVASVGLGILNGSS
                     VRSALDAKSDMVRPDFDPINSGFVGVQFGQLALIAFGVLLVCSEYTSGTVRAALGAVPG
                     RGLLYAGKITVAALVALAVAAVTVLIAFVATQRALGPYGVTLGQGESVRAVVGAPLYLA
                     LLCLLAVGVGMMLRSSALALTVMFVFVFVLSPVASSVPGLREVARYLPDQAGAQIMKVG
                     AQADPVVGPVAGLLILLAWTVAALAGGYAVLARRDA"
     gene            9765..9896
                     /locus_tag="EV193_RS25540"
                     /old_locus_tag="EV193_110127"
     CDS             9765..9896
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF033521.1"
                     /locus_tag="EV193_RS25540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_110127"
                     /product="lasso RiPP family leader peptide-containing
                     protein"
                     /protein_id="WP_130347269.1"
                     /transl_table=11
                     /translation="MENTQYETPMLAEIGDFAELTLCTPWGDCRDFLGCGRAPICVG"
     misc_feature    9976..9989
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.98"
                     /tool="antismash"
     gene            10001..11830
                     /locus_tag="EV193_RS25545"
                     /old_locus_tag="EV193_110128"
     CDS             10001..11830
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012936.4"
                     /locus_tag="EV193_RS25545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_110128"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_130347271.1"
                     /sec_met_domain="Asn_synthase (E-value: 8e-48, bitscore:
                     157.9, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFIVLPDHPEAWDALRDRPELAGARTVGHPSGRPWLVGWWREDD
                     LALVTAPDRRLALIGRTTLDPDEAARALRRARTPHDLDAYARRTVGSVHLVASLDGQVR
                     AQGTVSTARQLFTARIDGRTVAASNPGLLAELTESQLDERALAVRLLVPQVPWPLSAGC
                     VWSGVEPLAAGSWLHLDRAGAAHQIRWWRPPVSDRPLAEAAGAVRNALTDAITARVAGR
                     GTVSADLSGGLDSTALCFLADAEGADLLTYHVTPLDRANDDTAFAERAAAMMPRARHHT
                     IPAQRPASWFDVDPERYRAADTGEGPPVWGAGLAHLAELSETAASAGSTLHLMGIGGDE
                     LFGAMPAYLWSLIRHDPLRSLPVIHRYRLHNRWRLDAVVRGLADRTHFAGALARAAREL
                     TAPLPRPPALQLGWTGGSRMPGWATPHAVDLVREAFTAAARAGTEPLDADRVRHQVLEY
                     LMYEGTLIRQTRRAMAASGVEWDAPFLDDRVIEAALSVRIQDRVRRGRYKPVLVESLRG
                     AVPDDVLDRRTKGEFSAEMYQGMSRNREKFLALCDDLRLADLGLVDPAALRSALHGPSP
                     ESRHLAPFENTVACESWLRGSASPARQPAGGSR"
     aSDomain        11827..12078
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_EV193_RS25550_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="2.80E-26"
                     /identifier="RREFam002.1"
                     /label="EV193_RS25550"
                     /locus_tag="EV193_RS25550"
                     /protein_end="84"
                     /protein_start="0"
                     /score="82.3"
                     /tool="antismash"
                     /translation="MTIALSPHVLATETEGGLVLLDERAGKYWQLNGSGATTLRLLLDG
                     RSAEQVADELTKGDPGAVPRAVADVRALVDSLRAARLVV"
     gene            11827..12087
                     /locus_tag="EV193_RS25550"
                     /old_locus_tag="EV193_110129"
     CDS             11827..12087
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lasso_Fused_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015802121.1"
                     /locus_tag="EV193_RS25550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_110129"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_130347273.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 2.7e-25,
                     bitscore: 82.3, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="Lasso_Fused_RRE (E-value: 4.5e-08,
                     bitscore: 27.2, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 4.9e-11, bitscore: 36.9,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIALSPHVLATETEGGLVLLDERAGKYWQLNGSGATTLRLLLDG
                     RSAEQVADELTKGDPGAVPRAVADVRALVDSLRAARLVVAS"
     gene            12084..12503
                     /locus_tag="EV193_RS25555"
                     /old_locus_tag="EV193_110130"
     CDS             12084..12503
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015802122.1"
                     /locus_tag="EV193_RS25555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_110130"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_130347275.1"
                     /sec_met_domain="PF13471 (E-value: 2.5e-26, bitscore: 86.1,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIPVTAEESVPLTLGGQVLTRVSVGLARLLVLLPPRRLRQTLRL
                     ISTGARPATEEQARFARQAAVTVSHRCAGLGCLQRSVAAAIQCRLRGTWPDWCTGFRER
                     PFGAHAWVEVNGSPVGEPSDMSRFHTVMAVRGCRP"
     gene            12500..13480
                     /locus_tag="EV193_RS25560"
                     /old_locus_tag="EV193_110131"
     CDS             12500..13480
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006238714.1"
                     /locus_tag="EV193_RS25560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_110131"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_130347277.1"
                     /transl_table=11
                     /translation="MTSVSDAPAVRTEELYKFYGTTEAVSGLDLVVPAGITFGFLGPNG
                     AGKTTTIGMLCTLLLPTSGRAEVSGYDVVAQPHEVRDRIGLVFQESTLDLDLTAEENMR
                     FHAELFGLSRRQSKPAVDALLDLVELTDRKDSPVRDYSGGMRRRLEIARGLLNTPSVLF
                     LDEPTTGLDPQTRVAIWEHLHRLRRDSNVTLFLTTHHLEEAENCDRIAIMDHGDVVAHG
                     TPAELKAVVGADLVVLRTGDDHAAVRAAREGFGLDGEIGADGVRLRVDDGATFVPRLCA
                     GLGVAVHSVTVKPPSLDDVFLHYTGRSIRDDAGPTTLADIGRRSA"
     gene            13477..14343
                     /locus_tag="EV193_RS25565"
                     /old_locus_tag="EV193_110132"
     CDS             13477..14343
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF013245.4"
                     /locus_tag="EV193_RS25565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_110132"
                     /product="ABC transporter permease"
                     /protein_id="WP_130347279.1"
                     /transl_table=11
                     /translation="MTQVSDTPRARTEAPPEPAPAHPPRRNLRAIRMLWYREVVRLGRN
                     RTRIVMGLVTPLMFLLILGTGLESAAGQVGEGLRQYRSYLFPGVLVMATQAPAIAVGIS
                     VVWDRQAGFLRQALVAPVHRVSLLLGLCLGGAMSGALYGGLVLLIAGPVGVPYHPALLI
                     ALVEVSLVALMFTALGILAAVCIRKIETFQVVVSLCLMPLMFLSGAMFPPGGLPGWLGT
                     AVQLNPLTYAIDAIRRTLPGDLDMGGYAVGPQLWGWTPPVLVELAMVVALAFGALLVAA
                     RRFSRAE"
     gene            14367..14843
                     /locus_tag="EV193_RS25570"
                     /old_locus_tag="EV193_110133"
     CDS             14367..14843
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0030416 - methylamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007034324.1"
                     /locus_tag="EV193_RS25570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_110133"
                     /product="MauE/DoxX family redox-associated membrane
                     protein"
                     /protein_id="WP_130347536.1"
                     /transl_table=11
                     /translation="MDLVARLGLAVVLLVSGVLKIADPGQTYLAVRAYDVLPDALVRPA
                     ATVLPLAELALGALLLIGLGTRVVAVLSVLLLVVLTAGVAQAWARGLSIDCGCFGGGGE
                     VAAGQTEYPLEIARDLVFLAMAGWLVARPRSRLSVDGVLGARAGGEVVRKGADW"
     gene            14840..15625
                     /locus_tag="EV193_RS25575"
                     /old_locus_tag="EV193_110134"
     CDS             14840..15625
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020643769.1"
                     /locus_tag="EV193_RS25575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_110134"
                     /product="thioredoxin domain-containing protein"
                     /protein_id="WP_242613661.1"
                     /transl_table=11
                     /translation="MSSTDRDRRGAAVLAAAQRERRRRRLLTGAIAVAVVAAVVVVGLL
                     ATDASKNETEGQTIRVVDRARLLPEHAGARDGVVVVSGSPTAKITLDVYADFLCPVCAK
                     FHESSADRIDQLTNEGVLRVRYHMVPLLEHGSDPPGYSVDAANASLCAADAGRFVPFHD
                     SLLAGQPREGGRGYDKGQLTTLGRDVGITAPAFAECVQSGRYDQRLRDELARTVANPAL
                     GQPDGSGRTRFGTPTVVANGTLVRTTDADWLAGVLSARP"
     gene            15686..16099
                     /locus_tag="EV193_RS25580"
                     /old_locus_tag="EV193_110135"
     CDS             15686..16099
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EV193_RS25580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EV193_110135"
                     /product="hypothetical protein"
                     /protein_id="WP_130347281.1"
                     /transl_table=11
                     /translation="MSAATYRALRGIDKHLDEMARRPGANGTDEWRLAIMRSRAAVRVD
                     AAAKQLAAEAQAKDAPAELRGLAELVRAGGATWGECLLGKVDELPEVSAWLAAARDSGS
                     PVELPREEPPEKKPRLDYNDDYSKNTYLRDDDF"
     gene            16118..17473
                     /locus_tag="EV193_RS25585"
                     /old_locus_tag="EV193_110136"
     CDS             16118..17473
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EV193_RS25585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EV193_110136"
                     /product="hypothetical protein"
                     /protein_id="WP_130347283.1"
                     /transl_table=11
                     /translation="MSNADFDAQYAEVADEPRSGPIDKFMHLGGTFDEKLADLCQNIYE
                     RYEGKLTPLEKAAGGGYGNDQLREFRLGDYLDDMRKLTLEEFPVFFDAASFDRFADITT
                     SLDLAVSKINEARGYEGIGDLQSLFQHWEGTAADHFSDSLKPLGTAMRYQIAFAGEIGA
                     ASAHYEHLMKSMRVDAYGLAKNLMAKVDPPDSGSGLETALLVAGLIAGGAALFASGPLA
                     GVAGAVAVGEWGIAATSGLLQVQALDKDEVGDRAIIGGHPREYIPSCETRIEEILGTGA
                     KKGETVMHALAADMKHKDMDFLFLPRTELRGMTEPDNRRFKASEGYKVDQVADLRKAGV
                     ATLPTMAQYFEEARKAVEDLSVHFFDGIGQSAVANQQRNTFLHAATTLGDSFTRTRDYL
                     YEAGVAMTHIADNYSRMEGRHAEMITKYKTKMDNPDVTAPYDRYKPSKEKTT"
     misc_feature    16316..16318
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            17528..20344
                     /locus_tag="EV193_RS25590"
                     /old_locus_tag="EV193_110137"
     CDS             17528..20344
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF013124.4"
                     /locus_tag="EV193_RS25590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_110137"
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_130347284.1"
                     /transl_table=11
                     /translation="MAAGEQGWSFDVLGPLRVTRDGEPVELGAPQARAVLAVLVLHAGR
                     VISAERLIDEVWGASPPPSARVQLQGLISQLRRSLRTDAREAFIATGAGGYELRAPVGT
                     RDVDRFEEHVAAARDLISAGDVVEGAARLRTALATWRGRPLDGIEVPAARQAAEHLSEL
                     RLGALEDVVAAELELGEHGSLVGELAALVEENPLRERFRGQRMIALARSGRVPEALDAY
                     REWHSLLVDELGVEPSAEVRAIHAGVLRAEPGLRPEAVNSVIDPAKPRQLPPDRSGFIG
                     RRQLLGELTDEFVRPRDTPPVVVVTGAAGSGKTALSVRLAHSVGDSYPDGHLFAQLRGT
                     SADPVSPKAVLARFLRALRVPIDMIPADLDECAALFRDMLSGRRVLLVLDDAADEAQVR
                     LLIPAEAMCAVVITSRQRLSGLEWGRSVKIGALTDTESTALLAEVVGGERVAADPEAAR
                     TLADYCGGLPLALRIVGAQLVDRPHWTLLDMVDRMAAERGRLDWLAAGDIAVRASFALS
                     YERLGATHQTLFRRLGLLPVPTFASWVAAALVDTDEATGERLLADLVATNLVEPVGRAS
                     GGPRYRLHDLLRVFAAETVEREPEAERTTVVERAVGAWLYLAEQAAARLPGSVLQPAPG
                     HATRWARGLGEADRLVADAIGWFDAELPGLDSVIAVAAGQGLAEHAWELAVVCGVYFDH
                     QAVYPQWRQCYLRALPAARGAAADRGVASLLRGLGQIDIYEDRFADAVAALEESKEISE
                     RIGDRHGVARAILGLGTIHRVQGRMAEVLGCGDEAIPVLDELGDLHGGVQARIGRSGVY
                     LSEGRIDEARDVLDDAMQMCAKLGDQHRTANVHLAYGEMRLRENNATGAMKHFRTALRM
                     LESLGDQRCTAQVRLRIGRAHVALGHDAEATSVLADASAQFATLGNGTREAECALLLGQ
                     IAARTRTV"
     gene            complement(20467..21246)
                     /locus_tag="EV193_RS25595"
                     /old_locus_tag="EV193_110138"
     CDS             complement(20467..21246)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009155473.1"
                     /locus_tag="EV193_RS25595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_110138"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_130347286.1"
                     /transl_table=11
                     /translation="MLTISQLAAYAGVTVRAVRHYHQIGLLPEPERDHSGYRIYNAAAV
                     VRLIRIHTLAAAGVPLARVQELLDAGPEEFAEGVREIDKDLRAEIRRLRDTRERLARLA
                     AGEHLALPASVVGYLDRLRDLGVEERYIEMERDVWIMVAAQIPHEIDAIIADKHERLND
                     PDMVKLYSLINGALDLPADNPRIYEIADILERLMVRAVEAGEVRADGTDETFDDQFADL
                     LDATLLENAPGAKRLLAILEERGWKGWTRVERVPADG"
     gene            complement(21262..22023)
                     /locus_tag="EV193_RS25600"
                     /old_locus_tag="EV193_110139"
     CDS             complement(21262..22023)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004562501.1"
                     /locus_tag="EV193_RS25600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_110139"
                     /product="ABC transporter permease"
                     /protein_id="WP_130347288.1"
                     /transl_table=11
                     /translation="MTTYFFSDAVVLTGRTLRHVTRSMDTIITTVITPIAMMLMFVYVF
                     GGAIDTGPVSYVNYMLPGILLITIASGIAYTALRLFTDMNSGIFERFHSMPIARSGVLW
                     AHVLTSLVANLLSLVVVVGVAVLMGFRSGAGVLAWLAVLGILLLFTLALTWIAVIAGLS
                     AKTAEGGGAFSYPLIFLPFLSSAFVPTETMPGPVRWFAENQPVTSIVNTIRDLFAERPV
                     GGDIWTALAWCVGILVVAYVFAMVTYRRKIS"
     misc_feature    22175..22189
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.92"
                     /tool="antismash"
ORIGIN
        1 catggcggag gaaatggacg aggtgctcac cgcggtcggc cctcggctgc gggaactgcg
       61 ccggcgcgct ggcgccaccc tggcgtcgct gtcggagatc accgggatct cggtgagcac
      121 gctgtcccgg ctggagtcgg gtgagcgcaa gccgagcctg gagctgttgc taccgctcgc
      181 gcgggtgcac cgggtgccgc tggacgaact ggtcggcgca ccggagacgg gcgaccctcg
      241 ggtgcacgcg cggccgatcc gccgcgacgg gcgcacctac cttccgctga ccaggcggcc
      301 gggcggcgtg caggcgtaca agctgatcct gcccccgggc gaaggagagc cggacccgcg
      361 cgtgcacgag ggctacgagt ggttctacgt gctcaacggg cgggtgcgcc tggtactcgg
      421 cgagcgcgag accgtgctga aaccgggtga ggcggccgag ttcgacacgc atgtgcccca
      481 ctggttcgcc gccgcggact cgcgacccgc cgagatcctg tcactgttcg ggccgcaggg
      541 agagcggctg cacgtgcggg cccgtactac ctgatcaggg cttcgtgccg ccgtcgccct
      601 tcttgtcggt gagcagcgcc gtgatcctct cgatgccctt gcgcatgtcg gacatctcgc
      661 cgtggacctg cgtgaagccc tcgcgcatct cgctccgcaa ggacctgatc tcggcaccat
      721 gctggaccag cgtttggcct tgttggacct gggtttcgcg gagggcgctg atgtcgacgc
      781 cttgttggac ctgggtttcg cggagggcgc tgatgtcgac gccttgttgg acctgggttt
      841 cgcggagggc gctgatgtcg acgccttgtt cgatctgggt ttcgcggagg gcgctgatgt
      901 cgacgccttg ctggacctgg gtttcgcgga gggcgctgat gtcgacgcct tgctggacct
      961 gggtttcgcg gagggcgctg atgtcgacgc cttgttcgac ctgggtttga cggagggcct
     1021 tgatctccag gccgtgctcg atctggaccg tgcgcagggt ggtgatctcg acgccgtgct
     1081 cagtctgggt ctggcggatg gcggtgatgt cgcgcccgtg gtcgatctgg atctggcgga
     1141 tggcggtgat gtcgcggccg tggtcgatct gggtttcgcg gagcgcgttc agagatccgg
     1201 tgtgggcgcg caactgctgc tggacgtcgc ccacgtcttc gtgggccgtg gcggccagga
     1261 atcgggcggc tatcgcgtgg tcgcgcgcct ccgccacttg gcgtcggatg ccctcgtact
     1321 tgctcatgat ctccccatgg ggtcggtgcc tgtgctgacg aggccatctt caccaggaag
     1381 ccggattacg ccaaatggcc tatccacagg ccgaagttat ccacaggaag gcatgggccc
     1441 cttgacagag gtgatcagcg cggtcacggt cacgggctcg acggccatca ccacgtgggg
     1501 gttcttcgag tcacggaaca gcgcgccggc ggcgggccag gccagctcga cacagtcggt
     1561 ctgattggcg ctgtaggtgc tcttgcgcca ggtgagccgg tcgtgatcag gcgtggtcat
     1621 cgtgctcctc tcacggggcg cccagctcgc tcgccaggct ggcgatccac tccctcgatt
     1681 gttccgggtc cagcgcgacg gtgtcgagcc ttgccaggat cttctggtag gaggcgacgg
     1741 tctccttgcg ttcggggaac acgctggtgt tctcgttctc caggtgcagc accgggttga
     1801 tctcggtgaa ctccatcagc acgaagggcg tcgcgatggc ggcgtggaag ccgacctcgt
     1861 ccgggatcac ccgaatgacg acgcgcgggc gcaccgacag ccgcagcagg tggtgcaact
     1921 ggtccgattt gatctcaggc ccggggccgg tgcggctcag cgcgtactcg tcgacgaaga
     1981 accggcacag cggagcgcgg cggcggtcca ggatctcctg acggtgcagc cgtgcttcga
     2041 tccgctcgtc gatctcgtcg ggcggaatgg tcaccgattc ggccatgatc gcccggctgt
     2101 agtcggggat ctgcagcagg ccaggtatga gatggccgtg gtaggcgttg atcgccgccg
     2161 ccgcgtcctc gtgatcgatc aacgtacgga gttcagccgg caggcggtcg ccgaactcct
     2221 gcaaccagcc cggctcgtgc gcccgccggt tcagttccag cagccgttcg cgctcctcgc
     2281 cgacgatgtc gcacatggtc agcagcgacg acacgtccgc ttcgctcacc ccgcgtgtcg
     2341 cgcgcaggat gtggctgatc ttgctcggcg accagcgcat gcggcgggcc acctccttgc
     2401 tctccagtcc gcgctcgcga agcgcacgac gcagcgccag ccccagttca cgcatccgga
     2461 ccgtggattc cttgtcgccc atggctttcc cctcctttag gtgccaccac gttatggcgg
     2521 tcggccgccg tgcaccggcg cggcgcgcgc gaattccccc tatcggagct ggaagcacct
     2581 caggtaaccc ggtcgagtag acgtgccgaa ctccgacaga cgggacacca catgctcgag
     2641 cacgaccaga acctgttggt acgcttcaca aagctcgcca acgaagtgtc cacattggac
     2701 acacgggcgg cccgcgatct ggcgcgcgag ctgtcccagg cgctcgggtg gaccaacgcg
     2761 tcggagcagg cgtgccggat gcggcggctc gcactgtgca tgctcgacct ggcgctggag
     2821 ttccaggacc gcgccgccga cctggaccgc gtgatcatcg acatgcccgt aggctgcccg
     2881 cgtggggcga ttgatcgtga tcgaagggct tgacggcgcc ggcaagcgga ccatgtccga
     2941 cgggctgacc ggtgcgctgg agcgtcgtgg cgcgcgcgtg gtgcgccggg cgttcccgcg
     3001 ctatgacgag gacgtgcacg cggcgttgat caaggacgcg ttgcacgggc ggctcggtga
     3061 tctcggcgag tcggcgcacg gtatggctgt acttttcgcg ctggatcgct tgggcgccaa
     3121 ggaaaagctg gccgcggacc gggcctcggc cgacgtcgtg ctgctcgacc gctacatcgc
     3181 ctccaacgcg gcttacctcg ccgcacggct gcggcagagt gccgccggcg agggcgtgac
     3241 ctgggtgcgt gagctggaga tcgaccgctt cggcattccc gtgccggacg cgcagatcct
     3301 gctccgggtg ccgtccgacg tggccgccgc ccgggccgag cgccgcgctc gcgaagagac
     3361 tgatcgcgag cgggacacct gggagtcgga cggcggcctg caggcgcgcg tcgaggtcgt
     3421 ctacgaggac ctggccgccg cgtcctggct gtccccgtgg caggtcgtcg acggactgtc
     3481 cacagtcgat ttcgacgccc tcacggtgac ccttctcggc ggctcaccgg gataacccaa
     3541 ttagttggtg atgagccaca aatgccacgg cacgtttggc gcgggtgccc cgcctggctc
     3601 gtaaaggcag ctgaagttgt cgtaccagcc gttgttcact tgccaaatgc cctggttaac
     3661 gcacgtgtcg gagtccttat accacccgcc ggacgtgctc ccggccggcc cgacgtcgtt
     3721 cgaggtcgcc gcgctcgccg gggccgcgaa agccacggag ccgacgaccg ccaccgcggc
     3781 cagtacgccc gcgaaagtct tgcttgtcat gtattccaac cttcggtcaa tggcacaaca
     3841 aatgaccaca gatcggctat gtcaatgacc ccgccccaga tccccattga ccgacaccga
     3901 aaacgaggcc agtcatgctg cgctacaagg aaatggttac acctcgacta ctacccacga
     3961 ttcggcacgc tgtcaaggcg agcgtgccgc cgtccgacgg ccggtctgga gtgaccgccg
     4021 ccgagcttga tcggctggcg ctgatccggt aactcgcgtg gtgctggatg tggacggcgc
     4081 tgcgaatgct cgagtcgttg ggggatcaga ggtgcaccgc gcaggtgtgg ctgcgtatcg
     4141 gccgtgccca ggtgggcgat gcacagcgcg ggactcacgg gtgcagagcg cgggactcgc
     4201 gcgttcacga cacgcgcgag gcgggaagat cgcgtcacgc gtgctggtag tggatgacga
     4261 tccggctctc gccgagatgc tgacgatcgt gttgcgaggc gaggggttcg acaccgcggt
     4321 ggtcggcgac ggctcgcgat ctggcgcgtg agctgtccca ggcgctcggg tggaccaacg
     4381 cgtcggagca ggcgtgccgg atgcggcggc tggcactgtc catgctggac ttggcgctgg
     4441 agttccagga ccgcgccggc aagcggacat gtccgacggg ttgaccggtg cgctggagcg
     4501 tcgtggcgcg cgcgtggtgc ggcgggcgtt cccgcgttac accgaggacg tgcacgccgc
     4561 gttgatcaag gacgcgctgc acgggcggct cggcgagtcg gcgcacggta tggctgtact
     4621 cttcgcgctg gatcgcttgg gcgccaagga aaagctggcc gcggacctgg cctcggccga
     4681 cgtgctgctg ctcgaccgct acatcgcctc caacgccgcc tacctggccg cacggctgcg
     4741 gcagagcgcc gccggcgagg gcgtgacctg ggtgcgtgag ctggagatcg accggttcgg
     4801 cattcccgtg ccggacgcgc agatcctgtt gcgggtgccg tccgacgtgg caggtcgtag
     4861 acggactgtc cacagtagac ttcgacaccc tcgtggcgac tcttctcggc ggctcgccag
     4921 cccggcggtc agagtagtcc acccatttta cgataacgcg gcgcggtaat cactactgcg
     4981 aatgagtgca ctgtcgcgcg tcttttgagt atcatcgaag tggttgtccg gcatatgcct
     5041 gatggggtac cattttggtg gggagatgcg gatccatctg gggtgattac tactcgtcct
     5101 ggtgcgactg ccaggcgtta cgccggtctg gggaaatagt ttcacgtgtt tgagatggct
     5161 tcgtcgaacg cgccggcgtg cctatctgct gggggagatc gaattgggtg acacgcattc
     5221 tgattgtgac gtttattcgg attccaatgc gctcgttcgg gtggcattga tcgaagagga
     5281 tccgttgtac cgttccgccg ttcgccgggt ggtcgaggac gctggagccg tgaccgtcgt
     5341 cggcgaggcg gccagcgtcg acgagttcgc cgcaggccag tcatccggcg ggcacatcga
     5401 cgtcgcggtg atcggcatgt acgacatcac ggcgtgcatc gcggcggtcc aggcactcac
     5461 cgatggtggc gtgacgacca acggctcgac gccgcgcggc gtcctcgtca tggcgccgcg
     5521 gtactccgac gacgcgctgc tgagcgtgct gcgcgcgggc gcccgcggct acgtgatcaa
     5581 gggcggatcg caccgagaac tgctgctcgg gctgcgcgtg gtcgcggacg gcggcgcgat
     5641 gttcggctcc gcggtcgcgg gcaggctcgg cggttacctc gccgaaccgc gcgaccacga
     5701 cggccagcac ccgttcccgg cgctgaccgc gcgggagcgg caggtcctcg agttgatcgc
     5761 gaaggggcac agcaacagga ggatcgcccg cgcgctcgtg ctgtccgaga agaccgtgcg
     5821 caaccacgtg acccggctgt accgcaagct ggacgtcacc gacagaatcg ccgccgccac
     5881 tcgcgcccgc gacaacggaa tcagttagcg cgcaggcgag atcaggccgg tttcgtacgc
     5941 gatgatcacc agctggatcc ggtcccgcgc gtccagcttg tcgagcaggt gggccaggtg
     6001 cgtcttcacc gtcgccgtgc tcacgtgcag atgcctggcg atctccggat tcgacaggcc
     6061 cttggcgacc agcacgagca cctcgcgctc gcgcgcggtc agcccgctca gttccgacgg
     6121 caccactgtc gccggctccg ggcggcgaca gaactcggtg atcagccggc gggtcacggc
     6181 cggtgcgagc aggctctcgc cgtctgccac caccgacacc gcgcgcagca gatcggccgg
     6241 cgggatgtcc ttgagcagga acccgctcgc gcccgcgcgc agagcggcga acacataggc
     6301 gtccaggtcg aacatggtca agatcagcac cttgaccgcg ctggtcgcct cgccgtcaca
     6361 cagcgccttg gtcgcctcga tgccgtccat ctccggcatc cgcacgtcca tcagcaccac
     6421 atcgggcttg tgctcacgcg ccgcgtcgac cgccgtgcgg ccgttgtccg cctcggcgac
     6481 gaccgtgaag ccgggctcgg agtcgatcaa cagccggaaa ctcccgcgca gcagcgcctg
     6541 atcgtcggcg accaggacgc ggatcggatc actcacgaat ccccccgctg gaagggaagc
     6601 cgcgcggaca ccgcgaaccc gccgtcgggt gacgggcccg cgtcgaacgt gccgccgtag
     6661 agcgcgaccc gctcccgcat gccgatcaag ccgtgccccg ccgtgctccc gccgcgatcg
     6721 ggggcgcggc gaggaccatg gccggcggcg cccccgtcca ccacgtcgat gcacagcttg
     6781 ccgccactgt cggtgaccgt caccgtgcac gtggtcggcg cggcgtgctt gatcacgttg
     6841 gtgagcgcct cctgcacgat ccggtacgcc gagcggtcga ccccctccgg caggtggaca
     6901 ccgacccggg agtcgatgtc caccctcaca ccggccatcg acgcccgctc caccagctcg
     6961 ggcaggcgtt ccaaaccgtg ccctggccgg cggtcggccg ccgcctcctc gtcctcgctg
     7021 cgcaacaccc ccagcatgtt gcgcatctcg gcgagtgcac tgcggctggc cgactcgatg
     7081 tcgcgcaggg ccgcgctcgc ctcgtccggc cggcgggcca gcacgtggtt ggcgactccg
     7141 gccttcacgg cgatcaaccc gacctcgtgc gcgacgatgt cgtgcagttc gcgggcgatc
     7201 cgcaggcgct cctcggcgac cgcgctcgcc gcgacctcgc ggaccgagcg cgcggcgtac
     7261 gcccggcgct cgtgcatcgc ccgcccggcc gtccacgccg cgccggccag ggcggcgccg
     7321 accacgtgcg tcgccacggt gctcgcctgc caactcgacg agcccaccat cagcccgccg
     7381 gccaggacga tcacgctggt caggccgatc aacgaggtcg gaatccagcg cgacgccggc
     7441 accgtggcgc cgaccaggta cagggcgaac gccgtcgcca ggaacggctc gcggagcacg
     7501 ccgagcgcgg cggcgaggac cgacgcggcg gccaccacca cgagaaccgg caccggccac
     7561 cgccggcgga acgcgaccgg tagccccatg atcgccgcga cgccgaggcg caccggcacc
     7621 gggacggcgc ctatctgctg gtagttcgag atcacgaaga acaccgcggt gaaggtgacc
     7681 gcggcgatac ggtcgaggac gacgagctcg cgccggctca ggcgcctggt gaacacctgg
     7741 tgccgtgcgg actcgaccac gcggccaccg tactgcggtt gatctggccc ggcatcggcc
     7801 gcgagaacgt catcctcgcg gatgatgccg cgcgccggcg tcggttgcgg gagcgaggcg
     7861 ggaaatcggg tcgccggccg atgtcgcgcg taccggtcct gcggcacggt cggtacgtga
     7921 ttgaaatacg cgagctgacc aagcgatacg ggccggcggt cgccgtcgac gggctcacct
     7981 tcgacgtcgc tcccgggcgg gtgaccgggt tcctcggacc gaacggcgcc ggtaagtcca
     8041 cgaccatgcg gatgctgctc gggctggacc acccgagcgg cgggcgcgcc ctgctcggcg
     8101 gccgcccgta ccgcgagctg cgcgaaccgt tgcggatcgt gggcgcgctg ctggaggcac
     8161 ggtccacgca cggcggccgg accgcctacc accacctgct ctggctcgcc gccaccaacc
     8221 ggatcccgcg ccgcagggtg gacgaggtgc tcgggctcgt cgggctggag tcggccgccg
     8281 gcaagcgggc cggcacgttc tcactcggca tgagccagcg gctcggcatc gcggcggcgc
     8341 tgctcggcga tccggagatc gtgctgctgg acgagccggt caacgggctc gacccggagg
     8401 gcgtgcgctg gatcaggacg ctgatgaagg acctcgcggc cgaggggcgc accgtgctgg
     8461 tgtccagcca cctgatgagc gagatggcga tcaccgccga ccacctgatc gtgatcggcc
     8521 agggccggct gctcgcggac accacggtcg acgagttcgt cgccgccagc cgccgcggcc
     8581 atgtgcgggt cagcacaccg gaggcggacc ggctcgccgc gctgctcgac ggccgggccg
     8641 tgaccgtgcg ccgggtcgat ggcgcgctgg agatcacggg catggaggcc ggcgcggtcg
     8701 gggccgtcgc cggggccaac gggatcgcgc tggacgagct gagcacgcgc tcgtcgtcgc
     8761 tggaggacgc cttcctcgag ctgaccgccg gctcgaccga gtacagcagc cgcccgcagg
     8821 cggaggaggt tcgatgagcg tgtccaactc gccgttcgcc gtgctgcacg gcgagtggat
     8881 caagatccgc acggtgcggt cgacgctgct gtcgctggcc gtcgcggtcg tggccagcgt
     8941 ggggctcggc atcctcaacg gctcgtcggt ccgctccgcg ctggacgcga agagcgacat
     9001 ggtgcggccg gatttcgacc cgatcaactc cgggttcgtc ggcgtgcagt tcggccagct
     9061 cgccctgatc gcgttcggcg tgctgctggt ctgctcggag tacacctccg gcacggtccg
     9121 cgcggcgctc ggggcggtgc cggggcgcgg gttgctctac gccggcaaga tcaccgtggc
     9181 cgcgctggtc gcgctcgcgg tggcggcggt aaccgtgctg atcgcgttcg tcgccacaca
     9241 acgggcactc ggcccgtacg gcgtgacgct ggggcagggc gagtcggtgc gggcggtcgt
     9301 gggtgcgccg ctgtacctcg cgctgctgtg cctgctggcg gtcggggtcg gcatgatgct
     9361 gcgcagctcg gcgctggcgc tgaccgtcat gttcgtgttc gtcttcgtgc tctcgccggt
     9421 cgcgagcagc gtccccgggc tgcgcgaggt cgcgcggtat ctgcccgacc aggccggcgc
     9481 gcagatcatg aaggtgggcg cacaggccga cccggtggtc gggccggtcg ccgggctgct
     9541 gatcctcctc gcctggaccg tcgcggcgct cgccggtgga tacgcggtgc tcgcccggcg
     9601 ggacgcgtga cgaatgtccc ggaacgggat cgggacacgg tggggaacat tgtcccggcc
     9661 acccgggaca ttttctccga tacgttcgga aatgtccgcg gacaaactgg gggatttcaa
     9721 ccgggccccc ttctttcccg atacgctttc ggaggagatc aattatggag aacactcagt
     9781 acgagacgcc gatgctggcc gagatcggcg acttcgccga gctgacgctg tgcaccccgt
     9841 ggggcgactg ccgcgacttc ctgggctgcg gccgcgcgcc gatctgcgtc ggctgacctc
     9901 tcgggtgaca gttggccggc gatggccaca gtcgaattcg ttcgatttca gtcatcgccg
     9961 gctctcgccg tgaacattta tcgagaaaca aactggggcc atggaattca tcgttcttcc
    10021 ggatcatccg gaagcgtggg acgcattgcg cgatcggccg gaactggccg gcgcgcgcac
    10081 cgtcggtcac ccgtcgggcc ggccgtggct ggtcggctgg tggcgcgagg acgatctcgc
    10141 gctggtcacc gcgccggatc gccgcctcgc cctgatcggc cgcaccacgc tcgacccgga
    10201 cgaggccgcc cgcgcgctgc ggcgggccag gacgccgcac gacctggacg cgtacgcccg
    10261 gcgcacggtc ggcagcgtgc acctggtcgc ctcgctggac gggcaggtgc gggcgcaggg
    10321 cacggtgtcc accgcacggc agctgttcac cgcgaggatc gacggccgca ccgtcgcggc
    10381 gagcaaccct ggcctgctcg ccgaactcac cgagtcccag ctggacgagc gcgcgctggc
    10441 cgtgcggctg ctcgtgccgc aggtgccgtg gccgctgtcg gccggctgtg tgtggtccgg
    10501 cgtcgagccg ctggccgccg gctcctggct gcacctggac cgggccggcg ccgcccacca
    10561 gatccgctgg tggcgtccgc ccgtctcgga ccggccgctc gccgaggccg ccggcgcggt
    10621 gcgaaacgcc ctgaccgacg cgatcacggc gcgggtggcc gggcgcggaa cggtcagcgc
    10681 cgacctgtcc ggcgggctgg actcgaccgc gctgtgcttc ctggccgacg ccgagggcgc
    10741 cgacctgctc acctaccacg tgacaccgct ggaccgcgcc aacgacgaca ccgcgttcgc
    10801 cgagcgcgcc gcggccatga tgccgcgcgc ccggcaccac acgatcccgg cgcagcgccc
    10861 ggccagctgg ttcgacgtcg acccggagcg gtaccgggca gccgacaccg gcgaagggcc
    10921 accggtgtgg ggcgccgggc tcgcgcacct cgccgagctg tccgagacgg ccgcgtcggc
    10981 cggatccacc ctgcacctga tgggcatcgg cggtgacgag ctgttcggcg ccatgcccgc
    11041 ctacctctgg tcgctgatcc gccacgaccc gctgcgcagc ctgccggtga tccaccggta
    11101 ccggctgcac aaccggtggc ggctggacgc ggtcgtgcgc ggcctggccg accggaccca
    11161 cttcgccggg gcgctggcgc gggcggcgcg cgagctgacc gctccgctcc cgcgtccgcc
    11221 cgccctgcaa ctgggatgga ccggtggcag ccggatgccc ggctgggcaa cgccgcacgc
    11281 ggtggacctg gtgcgcgaag cgttcaccgc cgccgcgcgc gccggcaccg agccgctgga
    11341 cgccgaccgg gtccgccatc aggtgctgga gtacctgatg tacgagggca ccctcattcg
    11401 ccagaccagg cgcgccatgg cggcgtccgg ggtggagtgg gacgcgccgt tcctggacga
    11461 ccgggtgatc gaggccgcgc tgtccgtgcg gatccaggac cgtgtgcggc gcggccggta
    11521 caagccggtc ctggtcgagt cgctgcgcgg cgccgtgccg gacgacgtcc tcgaccggcg
    11581 caccaagggc gagttcagcg ccgagatgta ccaggggatg agccgcaacc gggagaagtt
    11641 cctcgcgctg tgcgacgacc tgcggctcgc cgatctcggg ctggtcgacc ctgccgccct
    11701 ccggtccgca ctgcacggcc cgtcgccgga gagccggcat ctcgccccgt tcgagaacac
    11761 cgtggcgtgc gagagctggc tgcgcggctc ggcgtcgccc gcccgtcaac ccgcaggagg
    11821 atcacgatga ccatcgcgtt gtccccgcac gtgctcgcca ccgagaccga gggcgggctg
    11881 gtgctgctcg acgaacgagc cggaaagtac tggcagctca acggttccgg cgcgaccacc
    11941 ctgcggctgc tgctggacgg gcgctccgcc gagcaggtgg ccgacgagct gaccaagggc
    12001 gaccccggcg cggtgccgcg ggccgtcgcc gacgtgcgcg cgctggtcga ctcgctgcgg
    12061 gcggcacgac tggtggtggc gtcatgacga tcccggtcac cgccgaggaa tcggtgccgc
    12121 tcacgctcgg cggccaggtc ctgacccgcg tgtcggtcgg ccttgcccgg ctgctcgtcc
    12181 tgctcccgcc ccggcggctg cgccagacgc tgcggctgat cagcaccggc gcccggccgg
    12241 cgaccgagga gcaggcgcgc ttcgcccggc aggcggccgt cacggtcagc caccgctgcg
    12301 ccgggctcgg ctgtctgcag cggtccgtcg ccgcggcgat ccagtgccgg ttgcgcggca
    12361 cctggcccga ctggtgcacc ggcttccggg agcgaccgtt cggcgcgcac gcgtgggtcg
    12421 aggtgaacgg atcaccggtc ggcgagccgt ccgacatgtc caggttccac acggtgatgg
    12481 ccgtgcgggg gtgccggcca tgacctccgt atccgacgcg ccggccgtgc gcaccgagga
    12541 gctgtacaag ttctacggca ccaccgaggc cgtgtccggc ctggacctcg tcgtgccggc
    12601 gggcatcacc ttcgggttcc tcgggccgaa cggcgccggc aagaccacca ccatcgggat
    12661 gctctgcacc ctgctgctgc cgacctcggg ccgcgccgag gtgtccggct acgacgtggt
    12721 cgcccaaccc cacgaggtcc gcgaccggat cgggctggtg ttccaggagt ccaccctgga
    12781 cctggacctc accgccgagg agaacatgcg cttccacgcc gagctgttcg ggttgtcccg
    12841 ccggcagagc aagcccgccg tggacgcgtt gctggacctg gtggagctga ccgatcgcaa
    12901 ggacagcccg gtccgcgact actccggcgg gatgcgcagg cgcctggaga tcgccagggg
    12961 actgctgaac acgccgagtg tgctgttcct cgacgagccg acgaccggcc tcgacccgca
    13021 gacccgggtc gcgatctggg agcacctgca ccggctgcgg cgggacagca acgtgacgct
    13081 cttcctcacc acgcaccacc tcgaggaggc ggagaactgc gaccggatcg cgatcatgga
    13141 ccacggggac gtcgtggcgc acggcacgcc cgccgagctc aaggccgtcg tcggcgccga
    13201 cctcgtggtg ctgcggaccg gcgacgacca cgccgccgtg cgggccgcgc gggagggctt
    13261 cggcctggac ggcgagatcg gcgcggacgg cgtgcggctg cgggtcgacg acggggccac
    13321 gttcgtgccg cggctgtgcg ccggactcgg tgtcgccgtg cactcggtga ccgtcaaacc
    13381 gccgtcgctg gacgacgtgt tcctgcacta caccggccgc agcatccgag acgacgccgg
    13441 gccgaccacg ctcgccgaca tcggcaggag gagcgcatga cccaggtcag cgacacaccc
    13501 cgggcgcgca ccgaggcacc gccggagccg gcgcccgcac acccgccgcg acgaaacctg
    13561 cgcgcgatca ggatgctctg gtaccgcgag gtcgtccggc tcggccgcaa ccgcacgcgg
    13621 atcgtgatgg ggctggtcac gccgctgatg ttcctgctga tcctcggcac cggactggag
    13681 tccgccgccg gccaggtcgg cgagggcctg cggcagtacc gcagctacct gttccccgga
    13741 gtgctcgtga tggccaccca ggcgcccgcg atcgcggtgg gcatctccgt ggtgtgggac
    13801 cgtcaggccg ggttcctccg ccaggccctg gtcgcgccgg tgcaccgggt gagcctgctg
    13861 ctcgggctct gcctcggcgg ggcgatgtcc ggcgcgctct acggcgggct ggtgctgctg
    13921 atcgccggcc cggtcggggt gccgtaccac ccggcgctgc tcatcgcgct ggtcgaggtc
    13981 tcgctggtgg ccctgatgtt caccgcgctg ggcattctcg cggcggtgtg catcaggaag
    14041 atcgagacct tccaggtcgt ggtcagcctg tgcctgatgc cgctgatgtt cctgtccggg
    14101 gcgatgttcc cgccgggcgg gctgcccggc tggcttggca ccgccgttca gctgaacccg
    14161 ctgacctacg ccatcgacgc gatccgccgg acgctgccgg gcgacctgga catgggcggg
    14221 tacgcggtgg gcccgcagct gtggggctgg acgccgccgg tgctggtcga gctggccatg
    14281 gtcgtggccc tggcattcgg cgcgctgctg gtcgccgccc gccgattctc ccgcgcggag
    14341 tgaccgtggg tcggctcgca gctgtcatcg acctcgtcgc ccggctcggt ctcgcggtgg
    14401 tgttgctggt gtccggggtc ctcaagatcg ccgatcccgg ccagacctac ctcgccgtcc
    14461 gcgcctacga cgtgctgccg gacgcactgg tgcggccggc ggcgaccgta ctgccgctgg
    14521 ccgagctcgc gctgggggcg ctgctgctga tcggtctcgg cacgcgggtg gtcgcggtcc
    14581 tgtcggtgct gctgctggtg gtgctcacgg ctggggtggc gcaggcgtgg gcgcgcgggc
    14641 tgtccatcga ctgcgggtgt ttcggcggcg gtggtgaggt ggccgccggg cagaccgagt
    14701 acccgctgga gatcgcccgc gacctggtgt tcctcgccat ggcggggtgg ctcgtggcgc
    14761 ggccgcgctc gcggctgtcg gtggacggcg tgctcggcgc gcgggccggt ggagaagtcg
    14821 ttcggaaggg ggccgactgg tgagttcgac ggacagggac aggcgtggcg cggcggtgct
    14881 ggcggccgca cagcgggaac ggcgcaggcg caggctgctg accggcgcga tcgcggtggc
    14941 ggtggtggcc gccgtggtgg tggtcgggct gctggccacc gacgcgtcga agaacgagac
    15001 cgaggggcag accatccggg tcgtggaccg ggcgcggctg ctgcccgagc acgccggcgc
    15061 cagggacggc gtcgtcgtcg tgtccggcag tccgaccgcg aagatcactc tcgacgtgta
    15121 cgcggacttc ctctgcccgg tgtgcgcgaa attccacgaa tcgagcgccg accggatcga
    15181 ccagctcacc aacgagggcg tgctgcgcgt gcgctatcac atggtgccgc tgctggagca
    15241 cggatccgat ccgcccggct actcggtcga cgccgcgaac gcgtcgctgt gcgccgccga
    15301 cgccggccga ttcgtgccgt tccacgacag cctgctcgcc ggccagccca gagagggcgg
    15361 ccgcggctac gacaagggtc agctgacgac cctcgggcga gacgtgggca tcaccgcgcc
    15421 cgccttcgca gaatgcgtcc agtcgggacg gtacgaccag cggttgcgcg acgagttggc
    15481 caggaccgtg gcgaacccgg cgctgggaca gccggacggc tcgggccgca cccggttcgg
    15541 caccccgaca gtggtggcca acgggacgct ggtgcggacc accgacgccg actggctcgc
    15601 cggcgtgctc tccgcccgtc catagcggtt ccttagtgcc gtgcgatgac atccctgccc
    15661 agaggcgagg caggggagga gcacgatgtc agcggctacc tatcgagcgt tgcgaggtat
    15721 cgacaagcac ctcgatgaga tggcccgtcg ccccggtgcg aacggcacgg acgagtggcg
    15781 gctggcgatc atgcgcagcc gggcggccgt gcgggtcgac gccgccgcga agcagctcgc
    15841 ggccgaggca caggcgaagg acgcgcccgc cgagctgaga ggtttggcgg agctggtccg
    15901 ggcgggcggg gcgacctggg gtgagtgcct gctcggcaag gtcgacgagc tgccggaggt
    15961 cagcgcctgg ctcgccgccg cgcgggacag cggctcaccg gtggaactcc ctcgggaaga
    16021 acctcccgag aagaaaccgc gcctcgatta caacgacgac tacagcaaga acacctacct
    16081 gcgggacgac gacttctgaa ctcgaaagga tctgaacatg tccaacgcgg attttgacgc
    16141 gcaatacgca gaggttgccg acgaaccccg ctcggggccg atcgacaagt tcatgcatct
    16201 cggcggcacc tttgacgaga aactcgccga cctgtgccag aatatctacg aacgctacga
    16261 aggcaagctc acaccacttg agaaggccgc agggggcggg tacggcaacg atcagttacg
    16321 cgaatttcga ctgggcgatt atctggacga tatgcggaag ctgaccttgg aagagtttcc
    16381 agtgttcttc gatgccgcga gttttgatcg tttcgctgat atcaccacat cgctcgatct
    16441 ggccgtgtca aaaatcaatg aggccagggg gtacgaaggc attggcgatc tccagtcgct
    16501 tttccagcac tgggagggta ccgcggcgga tcatttctcg gattcgctga aaccgctcgg
    16561 cactgcgatg cggtaccaga tcgccttcgc cggcgaaatc ggcgcggcct cggcgcacta
    16621 cgagcacctg atgaagtcca tgcgggttga cgcgtacggc ctggccaaga atctgatggc
    16681 gaaggtcgat ccgcccgatt cgggatcagg tctggaaacc gctctcctgg tggccggcct
    16741 catcgccggc ggagcggcgc tgttcgcctc gggtccgttg gccggcgtgg ccggcgcggt
    16801 cgccgtcggc gagtggggga tcgccgcgac aagcggtctg cttcaggttc aggcgctcga
    16861 taaggatgaa gtcggcgacc gtgcgataat tggtggacac ccccgtgaat acattccgtc
    16921 gtgtgagacg cggatcgagg aaatcctcgg caccggtgcc aagaagggtg agacggtgat
    16981 gcatgcgctc gccgcggaca tgaagcacaa ggacatggac tttcttttcc tgccccggac
    17041 ggagctccgc ggaatgaccg agccggacaa ccggcggttc aaggcgtcgg aggggtacaa
    17101 ggtcgaccag gtcgcggacc tgcgaaaagc cggtgtggcc acgcttccga ccatggcgca
    17161 atatttcgaa gaggcccgca aggcggttga agatctctcc gtccattttt tcgacggcat
    17221 cggccaatcg gcggtcgcga accagcagcg gaacacgttc ctgcacgcgg cgacgactct
    17281 cggcgactct ttcacccgaa cacgagatta cctgtatgag gccggcgtcg cgatgacgca
    17341 catcgccgac aactattcca ggatggaagg ccggcacgcc gagatgatca ccaagtacaa
    17401 gaccaagatg gacaacccgg atgtcaccgc tccctacgac aggtacaagc cgtccaagga
    17461 aaagaccacg taaccgtctg ccccgggtta gagtccggag aaatttggtc cggcggtgcg
    17521 aggtgcgatg gcggcggggg agcagggctg gtcgttcgac gtgctcggcc cgttgcgtgt
    17581 gacgcgcgac ggcgagcccg tcgaactcgg cgcgccgcag gccagagccg tgctcgccgt
    17641 gctggtgctg cacgccggcc gcgtgatctc ggcggaacgg ctcatcgacg aggtctgggg
    17701 cgcctcgcca ccgccctcgg cccgggtgca actgcagggc ctgatctccc aacttcggcg
    17761 gtccctgcgg accgatgcgc gagaggcgtt catcgcgacc ggagcgggcg gctacgagct
    17821 gcgcgccccg gtcggtactc gagacgtcga ccgcttcgag gagcacgttg cggccgcgcg
    17881 cgacttgatc tcagcgggtg atgtcgtgga gggagcggct cggctgcgga cggcgctggc
    17941 gacatggcgc ggccgtccgc tcgacggcat cgaggtgccg gccgcgcggc aggcggccga
    18001 gcacctgagt gagctgcggc tcggtgcgct ggaggacgtg gtcgcggccg aactggagtt
    18061 gggtgagcac ggctcgttgg tgggcgagtt ggccgcactg gtcgaggaga acccgctgcg
    18121 tgaacggttc cggggccagc gcatgatcgc cctggctcgc tccggccggg tgcccgaggc
    18181 cctcgacgcg taccgcgagt ggcactcgct gctggtggat gagctgggtg tcgagccgtc
    18241 ggccgaggtt cgggcgatcc acgcgggtgt tctgcgggcc gaacccggac tgcgacccga
    18301 ggcggtcaac tcggtgatcg atccggcgaa accgcgccaa cttccgccgg atcgcagcgg
    18361 cttcatcgga cggcggcagc ttctcggcga attgaccgac gagttcgtcc ggccacgtga
    18421 cacgccaccg gtcgtggtcg tcaccggtgc ggccggcagc gggaaaacgg cattgtcggt
    18481 gcgactcgcg cattcggtcg gcgattccta tccggacggg cacttgttcg cccaacttcg
    18541 cggcaccagc gccgacccgg tttcgccgaa agcggtactg gccaggtttc tgcgcgcgct
    18601 gcgagttccc atcgacatga ttcccgccga tctcgacgaa tgcgcggcgc tcttccggga
    18661 catgctcagc ggccggcggg tgctactcgt actggacgac gccgccgatg aggcacaggt
    18721 ccgcctgctc attccggcgg aggcgatgtg cgcggtcgtg atcaccagtc ggcagcggct
    18781 gagcggcctg gaatgggggc gttcggtcaa gatcggcgcg ttgaccgaca ccgagtccac
    18841 cgcgctgctc gccgaggtgg tcggcggaga acgggtggcg gccgatccgg aagcggcgcg
    18901 cactctcgcg gattactgcg gcgggcttcc gctggcgcta cgcatcgtcg gcgcacaact
    18961 ggtcgaccgt ccacattgga cactcctgga catggtcgac cggatggcgg ccgagcgcgg
    19021 caggctggac tggctggcgg cgggcgacat cgccgtgcgg gccagcttcg cgctgagcta
    19081 cgaacgcctc ggcgccacac atcagacgct gtttcgccgg ctcggcctgc tgccggtgcc
    19141 cacgttcgcg tcgtgggtgg cggcggcgtt ggtggacacc gacgaggcca ccggcgagcg
    19201 gctgctggcc gacctggtcg ccaccaacct ggtggaaccg gtcggccggg cgtccggtgg
    19261 gcctcggtac cgcctgcacg acctgctgcg ggtgttcgcc gccgagacgg tggagcggga
    19321 gccggaggcg gagcgcacga ctgtggtcga gcgcgcggtc ggggcgtggc tgtacctggc
    19381 cgaacaagcc gcggcgcgtc tgcccggcag cgtgctgcaa cccgcgccgg ggcacgccac
    19441 gcggtgggct cgcggactcg gtgaggccga ccggttggtg gcggacgcga tcggctggtt
    19501 cgacgccgaa ctgccgggcc tcgactcggt gatcgcggtg gcggcgggtc agggcttggc
    19561 cgagcacgcc tgggagctcg cggtggtgtg tggcgtctac ttcgatcatc aggccgtgta
    19621 cccgcagtgg cgccagtgct acctgcgcgc gctgcccgcc gctcggggcg cggcggccga
    19681 tcggggtgtg gcgtcgctgc tgcgcgggct cggccagatc gacatctacg aggaccgctt
    19741 cgccgatgcg gtcgccgcac tcgaggagtc caaggagatc agcgaacgga tcggcgaccg
    19801 gcacggggtc gccagggcga tcctcggtct gggcacgatc caccgggtgc aggggcgcat
    19861 ggccgaggtg ctgggctgtg gcgacgaggc gattccggtt ctggacgagc tgggcgacct
    19921 gcacggcggc gtgcaggcgc ggatcggtcg ctccggcgtc tacctgtcgg agggtcggat
    19981 cgacgaggcg cgggacgttc tggacgacgc gatgcagatg tgcgcgaagc tgggcgacca
    20041 gcaccgcacc gcgaacgtgc acctcgccta cggcgagatg cgcctgcggg agaacaacgc
    20101 gaccggcgcg atgaagcact ttcggacggc gttgcggatg ctcgagtcgt tgggggacca
    20161 gaggtgcacc gcccaggtgc ggctgcgcat cggccgtgcc cacgtggcgc tcggccacga
    20221 cgccgaggcg acctcggtgc tggccgacgc gtccgcgcag ttcgccaccc tcggcaacgg
    20281 cacccgcgag gccgagtgcg cactgctgct gggccagatc gccgcccgta cccgcaccgt
    20341 ctgatcgcga gttccgcgct cggacacggt gagtcccgcg ttggcgcacg tgtgggcgat
    20401 gcagggcgcg ggactcacgg gtgcacagcg cgggactcgc cggtgcacag cgcgggactc
    20461 gcgagttcag ccgtcggcgg gtactcgctc gacgcgggtc cagcccttcc agcctcgctc
    20521 ctccaggatc gccaggagcc gcttggcgcc cggtgcgttc tcgagcaggg tcgcgtccaa
    20581 cagatcggcg aactggtcgt cgaacgtctc gtcggtgccg tcggctctca cctcgccggc
    20641 ctccaccgcg cgaaccatca ggcgttccag gatgtccgcg atctcgtaga tccgcggatt
    20701 gtcggccggc aagtcgagcg ccccgttgat caggctgtag agcttcacca tgtcggggtc
    20761 gttcagtcgc tcgtgcttgt cggcgatgat ggcgtcgatt tcgtgcggta tctgggcggc
    20821 gaccatgatc cagacatccc gctccatctc gatgtaccgc tcctcgacgc cgagatcgcg
    20881 cagccggtcg aggtagccca cgacgctggc cgggagcgcc aggtgttctc cggcggcgag
    20941 ccgggcgagc cgttcgcgag tgtcccgcag ccgccggatc tcggcgcgca ggtccttgtc
    21001 gatctcccgg acgccctcgg cgaactcctc cgggccggcg tcgaggagtt cctgtacccg
    21061 ggccagcggc acgccggcgg ccgccagggt gtggatccgg atcagtcgca cgaccgcggc
    21121 ggcgttgtag atccggtaac cggagtggtc gcgttcgggc tccggcagca gcccgatctg
    21181 gtggtagtgg cgtaccgcgc gcaccgtcac cccggcgtac gccgccagct gactgatggt
    21241 gagcacgggt ctcagactgc ctcaggaaat cttccggcga taggtgacca tcgcgaagac
    21301 gtacgccacg acgaggatgc cgacgcacca ggcgagagct gtccagatgt cgccgccgac
    21361 cggccgctcg gcgaacaggt cgcggatcgt gttgacgatc gacgtcaccg gctggttctc
    21421 ggcgaaccaa cgcaccgggc cgggcatggt ctcggtgggc acgaacgccg agctgaggaa
    21481 cggcaggaag atgagcgggt aggagaacgc gccgccacct tccgctgttt tcgcggagag
    21541 accggcgatc acggcgatcc aggtcaacgc cagggtgaac aggagcagga tgccgaggac
    21601 cgcgagccag gccagcactc cggcccccga gcggaagccc atgagcacag ccacgcccac
    21661 gacgaccacg agcgagagca ggttggcgac cagcgaggtc agcacgtgcg cccacagcac
    21721 gcccgaccgt gcgatcggca tggagtggaa tcgttcgaag atcccgctgt tcatgtcggt
    21781 gaagagccgg agcgcggtgt aggcgatgcc cgacgcgatc gtgatgagca ggattccggg
    21841 cagcatgtag ttcacatacg agaccggccc ggtgtcgatc gcgccgccga atacgtagac
    21901 gaacatcagc atcatcgcga tcggcgtgat cacggtcgtg atgatggtgt ccatgctgcg
    21961 tgtgacgtgg cgcagagtcc gtcccgtgag cacgacggcg tcgctgaaga agtacgtggt
    22021 catccttgtt tcctcgtgtt cgtgccgatg accgcgagga agatctcctc cagggtcggc
    22081 tgcttctcga cgtactcgac gttggccggc gggaggagct gcttgagctc ggcgagggtg
    22141 ccgttcacga tgatccggcc ctcgtgcagg atcgcgatcc ggtcggccag ctgttcggcc
    22201 tcgtccaggt actgcgtggt gagcagcact gtcgtgccgt cgccggcgag ctccttgacc
    22261 gtgtgccaca cctcgatgcg cgcctcgggg tcgagcccgg cggtcggctc gtccaggaag
    22321 atcaccggtg aattcccgat caggctcatc gcgatgtcca gacggcggcg catgccaccc
    22381 gaatacgtcg acaccctgcg tgtggccgcg tcggtcagcg agaaacgccg cagcaggtcg
    22441 tccgcgatcg cgccagggtc ctcgaggtgc cgcagcctgg cgaccagaac gaggttctcc
    22501 cga
//
