LOCUS       NZ_SGWQ01000010        24446 bp    DNA     linear   CON 10-APR-2024
DEFINITION  Herbihabitans rhizosphaerae strain DSM 101727 Ga0310478_110, whole
            genome shotgun sequence.
ACCESSION   NZ_SGWQ01000010
VERSION     NZ_SGWQ01000010.1
KEYWORDS    WGS; RefSeq.
SOURCE      Herbihabitans rhizosphaerae
  ORGANISM  Herbihabitans rhizosphaerae
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Herbihabitans.
REFERENCE   1  (bases 1 to 269051)
  AUTHORS   Goeker,M.
  TITLE     Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing
            the most valuable type-strain genomes for metagenomic binning,
            comparative biology and taxonomic classification
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 269051)
  AUTHORS   Goeker,M., Huntemann,M., Clum,A., Pillay,M., Palaniappan,K.,
            Varghese,N., Mikhailova,N., Stamatis,D., Reddy,T., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-FEB-2019) Prokaryotic Super Group, DOE Joint Genome
            Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.12.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 226.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004216555.1-RS_2024_04_10
            Annotation Date                   :: 04/10/2024 19:27:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,690
            CDSs (total)                      :: 6,628
            Genes (coding)                    :: 6,561
            CDSs (with protein)               :: 6,561
            Genes (RNA)                       :: 62
            rRNAs                             :: 3, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2 (5S)
            tRNAs                             :: 54
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 13 of 67
            Pseudo Genes (incomplete)         :: 59 of 67
            Pseudo Genes (internal stop)      :: 5 of 67
            Pseudo Genes (multiple problems)  :: 9 of 67
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:31:17
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 91942
            Orig. end                         :: 116388
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            SGWQ01000010.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24446
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..24446
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24446
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:14446](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14446
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(1004..1660)
                     /locus_tag="EV193_RS25340"
                     /old_locus_tag="EV193_11087"
     CDS             complement(1004..1660)
                     /EC_number="5.2.1.8"
                     /GO_function="GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /GO_function="GO:0016018 - cyclosporin A binding [Evidence
                     IEA]"
                     /GO_process="GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /GO_process="GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015100909.1"
                     /locus_tag="EV193_RS25340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_11087"
                     /product="peptidylprolyl isomerase"
                     /protein_id="WP_130347528.1"
                     /transl_table=11
                     /translation="MSRIAIAAAVMLGTATLCAAPAQAAPGHKPVHCTFTPTPENPAAR
                     PVDPPRAKAKSHGDVRILMFTNHGAVVMVMNRDNAPCAVHNFAHLARNDFYDDSQCWRL
                     TNSARLGVLQCGDIYRAEEGGPGYKFDDEVTGKETYPRGTVAMGNQGPGTNGSEFFIVH
                     SHANIKPNYTVLGRVTHGMDTLDRIVAAGISPPGSQDGAPAKPVRIYKIVSLPGR"
     misc_feature    1654..1668
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.65"
                     /tool="antismash"
     misc_feature    complement(1742..1757)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.69"
                     /tool="antismash"
     misc_feature    1751..1765
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 18.03"
                     /tool="antismash"
     gene            1752..2885
                     /locus_tag="EV193_RS25345"
                     /old_locus_tag="EV193_11088"
     CDS             1752..2885
                     /EC_number="3.1.1.103"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012371.4"
                     /locus_tag="EV193_RS25345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_11088"
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="WP_130347203.1"
                     /transl_table=11
                     /translation="MFRQSTKRVAFAATAIAVATVAAIVPWSAQADGRADDHSDTLRVL
                     IGHHNHAGPGAVVVAGNGAGPWHLWAGAGNVPQNKPIGPADRIRIASQTKTMTAAIVLQ
                     LVGEGKIDLDSPIERYLPGLVQGNGYDGNKISVRQILQQTAGLAEFVKGGDSINRTYTL
                     EQLVRAGLSNPPAFAPGTSWGYSNTNYAVAGMLVERITGTSVNAAIADRITVPLGLSQT
                     RLPAPGDHTIGAPATHGYSGFQNGSIFFWQDVSNSFEPSYLSSAGGVVSTPEDMAKFVS
                     ALVAGKVVPQAQLAEMRKIVPTPYWDGYGLGLTRLELPCGGEAWGHYGDWLGYSSGTMA
                     TADGRYASMVTNTRVATALPEGSTRDNVLESALCGSG"
     gene            2960..4360
                     /gene="lpdA"
                     /locus_tag="EV193_RS25350"
                     /old_locus_tag="EV193_11089"
     CDS             2960..4360
                     /EC_number="1.8.1.4"
                     /GO_function="GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /GO_process="GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /GO_process="GO:0051068 - dihydrolipoamide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="lpdA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015804839.1"
                     /locus_tag="EV193_RS25350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_11089"
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="WP_130347205.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 9.3e-67, bitscore:
                     219.3, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTHFDVVVLGAGPGGYVAAIRAAQLGLSAAIVETQYWGGVCLNV
                     GCIPSKALLRNAELAHIFNHEAKTFGIQANGGVTFDYGAAFTRSRQVAEGRVKGVHYLM
                     KKNKIAQYEGWGSFTDANTLRVKLNDGGSETITFGNAIIAAGATTKLLPGTKLSERVVT
                     YEEQILSDELPDSIVIAGAGAIGVEFAYVLHNYGVQVTIVEFLDRMVPLEDAEVSKELA
                     RQYRKLGIDVLTSTKVESIDDSGDKVTVTVSKNGQQQTIETDKVLQAIGFQPRVEGYGL
                     ENTGVKLTERGAIDIDGRCRTSVPSIYAIGDVTAKLMLAHAAESMGVIAAETIAGAETM
                     ELDYAMIPRATYCQPQVASFGYTEEQARERGYDVKVAKFPFTANGKSHGLGDPTGFVKL
                     ISDAKYGELIGGHLIGPEVTELLPELTLAQQWDLTVHEVARNVHAHPTLGEAVKEAIHG
                     LAGHMINF"
     gene            4363..4716
                     /locus_tag="EV193_RS25355"
                     /old_locus_tag="EV193_11090"
     CDS             4363..4716
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018684146.1"
                     /locus_tag="EV193_RS25355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_11090"
                     /product="hypothetical protein"
                     /protein_id="WP_165401502.1"
                     /transl_table=11
                     /translation="MARVLVIGLDPAKIEGWDPAPVQAAIARGQARFDDLGIESDMCLV
                     VPDENPEAVIVEALTSAEYACVVIGGGIRKHEPLLELFEKVVNLVRRHAPGAAIAFNSG
                     PEDTADAAQRWLS"
     gene            complement(4830..5324)
                     /locus_tag="EV193_RS25360"
                     /old_locus_tag="EV193_11091"
     CDS             complement(4830..5324)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013223347.1"
                     /locus_tag="EV193_RS25360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_11091"
                     /product="N-acetyltransferase"
                     /protein_id="WP_130347207.1"
                     /transl_table=11
                     /translation="MSWLPDDFVHPVHVPVPGTALHLRPIREADTAIDYPAVMGSRERL
                     WEIFGPAWGWPTATMTYEEDRIDLLRHEKEIAAHESFNYALLDEAETAILGCVYIDPPE
                     RTGSDGEIAWWVVDDLVGGEVERALDALVPQWIAADWPFQKARYLGRDITWQDWLALPP
                     V"
     misc_feature    complement(5338..5353)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.27"
                     /tool="antismash"
     gene            complement(5353..6639)
                     /locus_tag="EV193_RS25365"
                     /old_locus_tag="EV193_11092"
     CDS             complement(5353..6639)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EV193_RS25365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EV193_11092"
                     /product="hypothetical protein"
                     /protein_id="WP_130347209.1"
                     /transl_table=11
                     /translation="MSINTMVVCDIGGCRQVAADFAALGKGAHEAGNAAQGSRQTASAG
                     WWGPAQQRFIDVMRGPRDNCDDLALTCELYARGMTDFADSIDIVVKTMNEALAKARAGG
                     LTVTDFTIVPPDHAAMVGSPPKKPDDFAPDNRAAYDQGVKAYDARVDVFNERVKVFNEC
                     SDIVKSARKKEDEAHANLQGDLAPRKEFNLDNWQVGGTAAQKVLKGIDHHNTARRRVVT
                     VLNDLDIEARTYTEIASAKSVSTSKLGPYFDKMAKTSGANRDMMLWLVRQLERGLPSGV
                     TTQAVPPGFADYEGPGRPRATVPSDARFAAPAIGGKAVPIIGDILTVGDELYNVARGKQ
                     TIEAGVIRSIGMVGMGYVGAAVGSTAGAAEGNREYGPVGGIIGGIVGAVTGDIQFSEGF
                     DQWSKKAYADSIDYQYNQEKLDEAKHAPR"
     gene            complement(6639..7010)
                     /locus_tag="EV193_RS25370"
                     /old_locus_tag="EV193_11093"
     CDS             complement(6639..7010)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EV193_RS25370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EV193_11093"
                     /product="hypothetical protein"
                     /protein_id="WP_130347211.1"
                     /transl_table=11
                     /translation="MPDGYGFDPGVLPGIAEQLKGAARSLDHAMGAQQPCVAFAGQSSA
                     QVGAAVRLVNTARVVLAEVLEDNASKINYTFGSYGEIENTQAGNMRLRELPSGEASDPG
                     GLWDAPERGNYLPGRKWPN"
     gene            complement(7025..7660)
                     /locus_tag="EV193_RS25375"
                     /old_locus_tag="EV193_11094"
     CDS             complement(7025..7660)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF042914.1"
                     /locus_tag="EV193_RS25375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_11094"
                     /product="SAV_915 family protein"
                     /protein_id="WP_130347213.1"
                     /transl_table=11
                     /translation="MPTPLERATLIAAEDLRGDDELLVLSLRGGGLEGRRTDRHEVLLF
                     AYSDPRELVESCGPAQPWVRLRKEELSALPARMEATVLVAIDAWHPEGERYAEQDVREM
                     EPLAYAEHVPPLTEAWIPSLPVVPGARAAQVELYAVRPGEPMLLAYGSLEDLRACCGEH
                     QAAIRVNPEDLDAVTAEAGAHGVLFDAVLDQELRYSGPVVDWAHRDVC"
     gene            7822..8232
                     /locus_tag="EV193_RS25380"
                     /old_locus_tag="EV193_11095"
     CDS             7822..8232
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020422799.1"
                     /locus_tag="EV193_RS25380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_11095"
                     /product="hypothetical protein"
                     /protein_id="WP_242613659.1"
                     /transl_table=11
                     /translation="MSAQLLTLPVPSHTTPDLHVPPERLHRDLATTLVAEDLAEQEWRL
                     DSHERLTCSEHGQWLHRCVHAKPHVNKITGYRWCRPCRAELEVAVDEIDGTVTVHCPKC
                     DRGAETKADFQLISACRQSLDAAHTARAAVAA"
     gene            complement(8265..8801)
                     /gene="idi"
                     /locus_tag="EV193_RS25385"
                     /old_locus_tag="EV193_11096"
     CDS             complement(8265..8801)
                     /EC_number="5.3.3.2"
                     /GO_function="GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="idi"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020673229.1"
                     /locus_tag="EV193_RS25385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_11096"
                     /product="isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="WP_130347215.1"
                     /transl_table=11
                     /translation="MGNSREQLPVELVDATGVGIGTCTVTEAHTAPGRLHRAFSVQLVD
                     PDGRLLLQRRAPVKTRFASRWSNTCCGHPAPGQRVEEAAVGRLAEELGLTATLTEVGSF
                     TYRAADTGSGFVEHEWDHVLLGTLTDGEPAPDPAEVSDYTWLDPAHVHSAMADDPHAYT
                     PWLSSVLRLVTAARH"
     misc_feature    8812..8821
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.11"
                     /tool="antismash"
     misc_feature    8819..8828
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.45"
                     /tool="antismash"
     misc_feature    complement(9058..9073)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.62"
                     /tool="antismash"
     gene            9123..10001
                     /locus_tag="EV193_RS25390"
                     /old_locus_tag="EV193_11097"
     CDS             9123..10001
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /NRPS_PKS="Domain: oMT (90-256). E-value: 8.7e-14. Score:
                     42.3. Matches aSDomain: nrpspksdomains_EV193_RS25390_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024880.4"
                     /locus_tag="EV193_RS25390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_11097"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_130347217.1"
                     /transl_table=11
                     /translation="MTTTPNGIVRNSYERDVWRYYHEKRQDMINLLPGEPDGFYHHHFG
                     IGDFDRSVADLPEVEREPKVLAEIHRLENALTDLIVDALDTVGPETRILDAGSGRGGTS
                     FVLHDRFGCSVDGVNFASYQVEFAQELAKARDCADKVRFHQRNMVDTGFPDDYFDVIVT
                     NETTMYVDLPEAFPEFARVLKPHGRYVLITWCINDAVCDGSSDIDQIDKNYVSKMHPRS
                     GYFAELAKHGFVPNHVLDFSRDAVPYWELRQLSKHRTGIEDAYLSAYRQNAIQEILVAT
                     DYVPTSAEGRG"
     aSDomain        9393..9890
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EV193_RS25390_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="8.70E-14"
                     /label="EV193_RS25390_oMT.1"
                     /locus_tag="EV193_RS25390"
                     /protein_end="256"
                     /protein_start="90"
                     /score="42.3"
                     /tool="antismash"
                     /translation="TRILDAGSGRGGTSFVLHDRFGCSVDGVNFASYQVEFAQELAKAR
                     DCADKVRFHQRNMVDTGFPDDYFDVIVTNETTMYVDLPEAFPEFARVLKPHGRYVLITW
                     CINDAVCDGSSDIDQIDKNYVSKMHPRSGYFAELAKHGFVPNHVLDFSRDAVPYWELRQ
                     LSK"
     gene            10001..11047
                     /locus_tag="EV193_RS25395"
                     /old_locus_tag="EV193_11098"
     CDS             10001..11047
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012568.4"
                     /locus_tag="EV193_RS25395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_11098"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_130347219.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 6.4e-41, bitscore:
                     134.3, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRTLCAQPVKDRVDAELIAFFDATANSMEPDAAELLVPLRAMLT
                     RGKHASTAFCHNTYRALGGDDTAAVWPKVCAALELAHLAMLTHDDVIDRSATRRGQDAV
                     HRAYASQHLAAGWTGDASRYGMDMALCVGDLLVIQSETLMDSASPDTAQAKALMRVMRQ
                     MYRDEVYGETLELRAQQDRVYQPDRCAKVARWKTGRWIASVSACGAVSAHADPETVAVM
                     DQFGELMGFAYQMRDDLLGVFGDSAVTGKPTMDDFRDGKPTVLIALAISQADAAGIETI
                     EELYGKPTLSEDDGDVLRAVIEESGAVKRVEEMINAHIGKAEELLSAHRAESSDLLALA
                     HAALNRSS"
     gene            11060..12046
                     /locus_tag="EV193_RS25400"
                     /old_locus_tag="EV193_11099"
     CDS             11060..12046
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012568.4"
                     /locus_tag="EV193_RS25400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_11099"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_130347221.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.7e-57, bitscore:
                     188.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEDRIRRTHELIGPALRAQVDAMHPDLARAVGYHLGWWDEHGTPS
                     RAYGKASRATICLAACTALGGRQSDAVPAAAALEMVHQQSLIHDDIIDDDTLRRGRPSA
                     WTAFGTPVAILAGDSMAGAAFALLAAKDGHAADVLRSAYLRVCDGQAADLALEGDLTAT
                     PEAYVEMALGKAGALFGASTAIGAVMAGADQDTVERMRQAGIDMGVAMQVVDDIRSIWQ
                     PSSGTGKTTKGDLVRGKLTYPVIAALRSPDSDELAALLRDPQECDTVKAAALVEDLGGR
                     ADAEEFAAQRLRLALGGLAAVPMSDEGREDLLRVFTWASATHLLTQF"
     gene            12070..13542
                     /locus_tag="EV193_RS25405"
                     /old_locus_tag="EV193_110100"
     CDS             12070..13542
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012647.4"
                     /locus_tag="EV193_RS25405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_110100"
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_130347223.1"
                     /sec_met_domain="T2TS (E-value: 1.5e-64, bitscore: 212.4,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRDAIERADTIVGELDNRPVAGSAYSTAWAARLVHDDGRPVFEQA
                     REWLRTHQHADGSWGSAVPNAYDRLVCTLAAVLTLSEVPGEWAAGAVRAGVDYLREHAA
                     DWRDAPGQIIGFEIVAPYLVEQARAAGLLEIDSRTELALLREEKLALVPEGALTSQPTA
                     LLYSLEALDDLVSVPDVLKFAAPDGSMSSNPAATAAVWAATKDPAALTYLRDAARSAGD
                     GGLPEIYPIDVFEPAWTIYLLDRAGLKPSGVQQHVERFLRLSGEDGAPLGSSADFPLPD
                     SDCTALVAIVAHSFGYETTPLLEALLPFERDDHFAGLPHERFAPVSGNAHVLEALSQQP
                     HRFAAQIGKTRDFLLDARRESAWWHDKWHFSDHYATAQAVFGLAGATEPGTLAGTWRWL
                     LDGQHPDGSWGAAGGQAEDTAYAVLSLDALAPHHGPVPEDTYRRAHAYLREHLDAPDYA
                     ELWIGKSLYTPPTVVRAAVAAAWVISGQADDE"
     misc_feature    13129..13131
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            13535..14446
                     /locus_tag="EV193_RS25410"
                     /old_locus_tag="EV193_110101"
     CDS             13535..14446
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EV193_RS25410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EV193_110101"
                     /product="terpene synthase family protein"
                     /protein_id="WP_130347225.1"
                     /sec_met_domain="T1TS (E-value: 2.9e-10, bitscore: 34.1,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEPTYATAAQCVHLSALGLAACADLQRWAAEEWPTFPQLHLAGA
                     GYGEAMVAPWATADQVRLTGRMCVWAHALDKFVDREITERAQLDDFVDRCNTVVRTGEP
                     DHGNQLLRILSDWQREFAELPDYSPLAAVWERKFDSCLRGHQYNWVVGSARERGEEPEV
                     DVAAYLAHSDSVAVGLVQVPRWVAYGGAELPDRLDVLLPALDHIAVAVRLANDLATIDR
                     ERDEPGQNNILMYGVSPDWVRAEYVDRVAAVRRRLAPLVEENFMPAIGLVRLAEWSVGV
                     YERRDMAPAMSLPAAGSEARTR"
     gene            14443..15645
                     /locus_tag="EV193_RS25415"
                     /old_locus_tag="EV193_110102"
     CDS             14443..15645
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="EV193_RS25415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_110102"
                     /product="cytochrome P450"
                     /protein_id="WP_130347227.1"
                     /sec_met_domain="p450 (E-value: 5.3e-16, bitscore: 52.4,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTRNTTPADVPVRDFNHHADPDLRIDPFATFDRFRDERVFWTPE
                     LDGFWVLTRYDDIRAVLRDTERFSNESTAIPPIDWNGQRLIPVELDPPDHGKYRTLLTR
                     YLNGPANAVLATAVEKECLRLVERLAPAGECELVGDFARKLQNALLGAMFDEPGEEDDV
                     PDFGRLSDDLVQASEPARRSRAIRDIMAYLRRAIAGHQTRRTDSTSLIASLSGAEIDGR
                     PLSESETLNMAFLMTMAAIDTLTSSMSFGFRYLAEHPAHQRRLAEDPGAAAAAADELLR
                     LHSVVSIARIVARDTEFAGVRMRAGERVMLSLSLAGRDPHQYPEATTADFDRPNRASHL
                     AFGFGAHRCAGARIATGGMIAALREWHAAIPEYSVRLGTELVTGGGAAASLESLPLVWK
                     T"
     gene            complement(15649..17250)
                     /locus_tag="EV193_RS25420"
                     /old_locus_tag="EV193_110103"
     CDS             complement(15649..17250)
                     /GO_function="GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010313903.1"
                     /locus_tag="EV193_RS25420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_110103"
                     /product="GMC family oxidoreductase N-terminal
                     domain-containing protein"
                     /protein_id="WP_130347229.1"
                     /transl_table=11
                     /translation="MAEFDYVIVGAGPAGCALANRLSADPDVSVLLIEAGDQDTNPMIS
                     IPGAAAQLFGDPDAMWFHPTHPFGPAGEPEVWLRGKTLGGSSSVNGMVYNRGSREDYDE
                     LERLGNPGWGWDHILAAYKEIEDNPFGASDVRGAGGPLRVSTRTEGDPLLDDVIDAGGE
                     LGWQRAEDLNENDDERVGYTMATIRDGLRVSAAGAFLHPVAERDNLTVAVHTTVDRVVI
                     EDGRAVGVLGRQDGEAFEATATREVILAAGALASPKILQLSGVGPAETLREAGVDVVVD
                     SPNVGARMREHRAFQMQVRLTEDLGYNKILSTPEGQQAAMVEYQTSQTGVLAAPAFEIV
                     GFFKTRPDLDRPDAQFQIAPFSIAPREQGKALEIEREPGMMGIGYALRPTSEGSVRITS
                     ADPDAPVDIDANYLDTEYDRTTTVAIFRTLRGLFGTGPLAKRVERETLPGPEVDTDQEI
                     QDFALTVGSAGYHAVGTCAMGPNDDDVVDSRLRVRGVANLRVVDASVFPTLVSGNLNGP
                     VSALGWRAADLIIEDA"
     misc_feature    17330..17343
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 16.06"
                     /tool="antismash"
     gene            17442..19883
                     /locus_tag="EV193_RS25425"
                     /old_locus_tag="EV193_110104"
     CDS             17442..19883
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019974.4"
                     /locus_tag="EV193_RS25425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_110104"
                     /product="nitrate- and nitrite sensing domain-containing
                     protein"
                     /protein_id="WP_130347231.1"
                     /transl_table=11
                     /translation="MRLAPGKSSGLRSIRLRMLAIVLIPSAALLILGVGASGYLVYQGS
                     TAQDWATTMRETAPPGTQFVAEVEEERRLSLFRLGGERAAAEPLAAQRQRLDTSLLGMQ
                     SMSASFSKLNPDALKEGNEAFQKVLAMLPTIRQGVDAGQAPPMDVYAYYSGLTEAVRMG
                     VQGLAKTAPDPVTAVEESTSVTVFTAADAMSRGHALAVGAVVNGGLSVAEYQEFSRQVG
                     RYRTTMESTVPLLSKPLQERYATLAASDQWKRLGEVENALLLRGPRPGPARDLRPLPIS
                     IPDWQASASHVNTELLDMYSEHHSYAQSVAEETGERTFVNSLLAGGGILLLTIIATWVA
                     IVLSNRVVRRLKKLRAETLELADKRLPMIVDRLRGGEQIDVAREVPPLDHGADEIGQVA
                     EAFNKAQRTAVIAAAQEAEIQNGVKAVFLNIAHRSQVVVRRQLEVLDKAEREQEDPDQL
                     EWLFQLDHLATRARRNAENLIILGGEQPGRQWRNPVPLLEIVRSAIGETEQYRRVQTGR
                     LPDLAISGAAVADLIHLLAELVDNATQFSPPDSRVEVRGNTVGKGVVVEIEDQGLGILT
                     DIREGINTSLQNPPDFSVMALSEETQLGLFVVSQLAARHGISVTLVDSAYGGIRAIVLI
                     RSAIIAQDPDEPAPAEQPQEGATEREPDILRRLRRLSDYSAHEYYSSAAPTQVLDAPAT
                     STGSTEADPAVQWPQQEVSNGAHHSEVADQRGSAPTEVITGNGRNGGGDAQRAEDGRPE
                     LPRRRRQANLAPQLASETELPVEQSQTQPDDDADGVSTAERARDRMAAFQRGTREGRAA
                     P"
     gene            19932..20339
                     /locus_tag="EV193_RS25430"
                     /old_locus_tag="EV193_110105"
     CDS             19932..20339
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007026981.1"
                     /locus_tag="EV193_RS25430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_110105"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_130347233.1"
                     /transl_table=11
                     /translation="MENSGTTDLNWLLDDLVTRAVGARHAVVLSTDGLCVGRSRDLNRE
                     DSEQLSAMASAFQSLARGVGRHFEGGEVRQTVVELDNAYLVVTSAGTGACLALIASEDA
                     DIGMLAYEMNIMVKKVGAYLVAKPRVSGFHM"
     misc_feature    19969..19984
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 20.89"
                     /tool="antismash"
     gene            20348..20722
                     /locus_tag="EV193_RS25435"
                     /old_locus_tag="EV193_110106"
     CDS             20348..20722
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020420236.1"
                     /locus_tag="EV193_RS25435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_110106"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_130347235.1"
                     /transl_table=11
                     /translation="MKHGRESWYDDEAGPLVRPYTVTRGRTRSGHGLDLDMITLVVSNA
                     SGHTVVDPEYAQILRMCRYPLSIAEVSAKLGLPLAVIKILIADLIEDGLLIFRSPPSPL
                     DTETPDMDILQAVLDGIRRL"
     gene            20703..21293
                     /locus_tag="EV193_RS25440"
                     /old_locus_tag="EV193_110107"
     CDS             20703..21293
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020640885.1"
                     /locus_tag="EV193_RS25440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_110107"
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_130347237.1"
                     /transl_table=11
                     /translation="MASVGSDPRTEPGLGTSAVKVLIAGGFGVGKTTMVASVSEVAPLR
                     TEERISDMGGKVDDLGGVEGKNTTTVALDFGRITINESLILYLFGTPGQERFWFMWDEL
                     SLGALGAVVLADTRRLDRCFAAVDYFERRQIPFVLAVNNFFGEQRYTVDEVRDAADLDS
                     NVPIMQCDVRQRESSKVVLSTLLEHLMTMAAQR"
     gene            complement(21419..21952)
                     /locus_tag="EV193_RS25445"
                     /old_locus_tag="EV193_110108"
     CDS             complement(21419..21952)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015104749.1"
                     /locus_tag="EV193_RS25445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_110108"
                     /product="NAD(P)H-binding protein"
                     /protein_id="WP_242613660.1"
                     /transl_table=11
                     /translation="MTAVVRKPLHPNEVRGDASTVDDVARLTGDHDAAISATRPPDGSE
                     HELVETAKALLAGVARSGTRLLLVGGAATLRAPGGGLVLDDRRYLPEVAADIARACAEQ
                     HAVLRESTVDWTYLSPPANLVPGERTGVYRLGSDELVVDANGESTISIEDLAVVLLDEI
                     EHPKHRRTRFTAAY"
     gene            complement(21949..22899)
                     /locus_tag="EV193_RS25450"
                     /old_locus_tag="EV193_110109"
     CDS             complement(21949..22899)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058717.1"
                     /locus_tag="EV193_RS25450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_110109"
                     /product="EamA family transporter"
                     /protein_id="WP_130347241.1"
                     /transl_table=11
                     /translation="MLSNRTTVLLVTAVAPAVWGSTYLVTTELLPPDRPLLAALLRTLP
                     AGLLLLAFTRRLPRGVWWWRALVLGALNMAVFMALLFVAAYRLPGGVAATVGALQPLIV
                     AAFSVGLLGERLTGRTLVAGAAGVLGVGLLVLKADARLDFLGVAAALGGVLSMALGVVL
                     SKRWTSPESPLTTTSWQLVAGGLLLLPVALLVEGGPPVLTAGNIAGYTYLTTIGAALAY
                     VLWFRGIRALSPTNVTFLGVLSPLVATALGWIVLGQSLTALQALGALLAVGAVVGQNIR
                     RTRTPKEKTCESSFSEHVDLSAGGSSPKPSPVATG"
     gene            22962..23459
                     /locus_tag="EV193_RS25455"
                     /old_locus_tag="EV193_110110"
     CDS             22962..23459
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020667816.1"
                     /locus_tag="EV193_RS25455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_110110"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_130347243.1"
                     /transl_table=11
                     /translation="MADHVDMVLRQWADERPDLDASPMAIVGRLSRLSRMVDNALTDYF
                     AEHGLDRASVDVLFTLRRSGSPYRLTPSELTRSSMVTSGAITQRLDRLEARGLIARRRS
                     EADGRGVVVALTDEGHELTEAVLPGHLDNERRLFDALTPSQRDTFARTLRKVLESLGDK
                     TD"
     gene            23494..23799
                     /locus_tag="EV193_RS25460"
                     /old_locus_tag="EV193_110111"
     CDS             23494..23799
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EV193_RS25460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EV193_110111"
                     /product="hypothetical protein"
                     /protein_id="WP_130347245.1"
                     /transl_table=11
                     /translation="MTVVLLGREPKVVKSVGSELRARGFSVVECTGDDEAVAAVDSGDA
                     TAIVIGGGVEPASRERVTSAARAHGVAVVAGRRGDGPLATYVDEVLVPELREVSAA"
ORIGIN
        1 cgaccggcgc cgctccggcg ttcacggtcg ccggcctgtg cggggcggcc acggtgctgt
       61 ggcaggccgg caaccgcgcg gccggcggca cactggtcgg cgcgacactg gtagtgcaac
      121 tcgtcgcgcc ggtggtgctg atgagcgggg gcttcgacgc gcgcgagacg atcgccatcg
      181 tcggtctggt gctcgtggtg cccgcgatcg tgggcgcggc catcaccgtg tcggcgtcga
      241 ccgtcatccc gtcgagcgtg cccgtccgac ccgacctgcg caccacgatt gccggcgcgg
      301 tggcagccgt gactccggcg ctgttcccga ttctgcagcc gagccggcag gagatgcgga
      361 gcaacccgga cacgatcagc gactacttcc tctactgcgg cctgatcgcg ctggtgatcg
      421 cgatcgcggc gggcatggcc gccggcctgc tcaacctgct cgcctccgcc gcactcggcc
      481 tgctactcgg ggcgttcggc atgatgatca tgccgtcggt cgaggtgctc agggaattcg
      541 ccgtggtcgc gatcatcgcg gcgatcggca gcgtggtgat cggcgtgctg gtcgcgcagt
      601 cccgctggcg attccagatc ggcatgggcg gcctcgccct cgtcgtggtg ggcctgttcg
      661 tgttcttcct gatggtcaac agcgacgacg tgcggtctta ccgcgacttc ctggacggtg
      721 ccacgccggt tctcgtggtg atcggcgtga tcgccgcgct gtccacggtg acctcggtcg
      781 ggtcggtcgt ggcacggcgg tccgacacac cggcgatcgt ggtcggactc accgtgccgt
      841 tcaccgtcgc ggtgatcggg ctcatcacct ggctgatgct gaccgcgccg gacgacaagg
      901 caccgctgac gaacatgctc ccggcgtcgg ccgccggtgt gctgatcgcc ggcgtactcg
      961 tcgcgatgat cgtcaaccgg tacggcgagt cacagcggac cgatcaccgg ccgggcagcg
     1021 acacgatctt gtagatccgc accggcttgg cgggcgcgcc atcctgcgac cccggcgggc
     1081 tgatgccggc ggccacgatc cggtcgagcg tgtccatgcc gtgcgtgacc cggccgagca
     1141 cggtgtagtt cggcttgatg ttcgcgtgcg agtgcacgat gaagaactcg ctgccgttgg
     1201 tgcccggccc ctggttgccc atcgcgaccg tgccgcgcgg gtaggtctcc ttgccggtca
     1261 cctcgtcgtc gaacttgtag ccgggcccgc cctcctcggc gcggtagatg tcaccgcact
     1321 ggagcacgcc gagccgggcg gagttggtca gccgccagca ctgcgagtcg tcgtagaagt
     1381 cgttgcgagc caggtgcgcg aagttgtgca ccgcgcacgg cgcgttgtcc cggttcatca
     1441 ccatgacgac ggcgccgtgg ttggtgaaca tcaggatccg cacgtcgccg tgcgacttgg
     1501 ccttggcgcg aggcgggtcg acgggccgcg ccgccgggtt ctccggggtc ggcgtgaacg
     1561 tgcagtgcac cggcttgtgg ccgggagcgg cctgtgcggg agccgcacag agtgtcgccg
     1621 taccgagcat gacggcggcg gcgatggcga tccgggacat cgttgtcatg cggtcaacgt
     1681 agcgcctgcc gacccggtga tcgagtccct tcgcttgtcc ggacagtcga agaacagtag
     1741 cgttcacaaa tgtgttcaga caatcgacga agcgggtggc cttcgccgcc accgcgatcg
     1801 cggtggccac agtggccgcc atcgtgccgt ggtccgcgca ggcggacggt cgggccgacg
     1861 atcacagcga cacactgcgt gtcctcatcg gtcaccataa ccacgccggc cctggcgcgg
     1921 tggtggtcgc gggcaacggc gccggcccgt ggcacctgtg ggccggagca ggcaacgtgc
     1981 cccagaacaa gccgatcggc cccgccgacc ggatccggat cgcgagccag accaagacga
     2041 tgaccgcggc gatcgtgctg caactggtcg gcgagggcaa gatcgacctg gactcgccga
     2101 tcgagcggta tctgcccggc ctcgtccagg gcaacggcta cgacggcaac aagatcagcg
     2161 tccggcagat cctccagcag accgcggggc tcgccgagtt cgtcaagggc ggcgacagca
     2221 tcaaccgcac ctacacgctg gagcagctcg tccgcgccgg cctgagcaac ccgccggcgt
     2281 tcgcacccgg cacgagctgg ggctactcga acaccaacta cgcggtcgcc gggatgctcg
     2341 tcgagcggat caccggcacg tcggtcaacg cggcgatcgc ggatcgaatc accgtgccgc
     2401 tcggcctctc ccagacccgg ctgcccgcac cgggcgacca cacgatcggc gcacccgcca
     2461 cgcacggcta ctcgggcttc cagaacggct cgatcttctt ctggcaggac gtatccaaca
     2521 gcttcgagcc gtcctacctg tccagcgccg gcggggtcgt gtcgactccg gaggacatgg
     2581 cgaagttcgt cagcgcgctg gtggccggca aggtcgtgcc gcaggcgcag ctcgccgaga
     2641 tgcgcaagat cgtgccgacc ccgtactggg acggctacgg gctgggcctg actcgcctgg
     2701 aattgccctg cggcggcgag gcgtggggcc actacggcga ctggctcggc tactcctcgg
     2761 gcacgatggc caccgccgac ggacgctacg cgtcgatggt gaccaacact cgggtcgcga
     2821 ccgcgctgcc cgagggttcg acgcgtgaca acgtgttgga atccgcgctc tgcggcagcg
     2881 ggtgacacct gtctcacccg gccccgagcg ctccgaggcg ctcggggcca cggcctgttc
     2941 gtcccatatc gtgtgtccca tgagcacaca ctttgacgtc gtggtcctcg gcgccgggcc
     3001 aggcggctat gtcgccgcga tccgggcggc acagctcggt ctgtcggccg cgatcgtgga
     3061 gacccagtac tggggcgggg tctgcctcaa cgtcgggtgc atcccgtcca aggccctgct
     3121 gcgcaacgcc gaactcgcgc acatcttcaa ccacgaggcg aagacgttcg gcatccaggc
     3181 caacggggga gtgaccttcg actacggcgc ggcgttcacc cgcagccggc aggtcgccga
     3241 ggggcgcgtc aagggcgtgc actacctgat gaagaagaac aagatcgcgc agtacgaggg
     3301 ctggggcagc ttcaccgacg cgaacacgct gcgggtgaag ctgaacgacg gcggctcgga
     3361 gacgatcacc ttcggcaacg cgatcatcgc ggcgggcgcg accacgaagt tgttgcccgg
     3421 caccaagttg agcgagcgcg tggtcaccta cgaggagcag atcctctccg acgagctgcc
     3481 ggacagcatc gtgatcgccg gcgccggcgc gatcggcgtc gagttcgcct acgtgctgca
     3541 caactacggc gtgcaggtga ccatcgtcga gttcctggac cggatggtgc cgctggagga
     3601 cgccgaggtg tccaaggaac tggcccgcca gtaccgcaag ctcggcatcg acgtgctcac
     3661 ctccaccaag gtggagtcga tcgacgacag cggcgacaag gtcacggtga ccgtgtcgaa
     3721 gaacggccag cagcagacca tcgagaccga caaggtgttg caggccatcg ggttccagcc
     3781 gcgggtggag ggctacggcc tggagaacac cggcgtgaag ctgaccgagc gcggcgcgat
     3841 cgacatcgac ggccggtgcc gcacgagcgt gccgagcatc tacgcgatcg gcgacgtcac
     3901 ggcgaagctg atgctggcgc acgccgccga gtcgatgggc gtgatcgcgg cggagaccat
     3961 cgcgggtgcg gagaccatgg agctggacta cgcgatgatc ccgcgcgcga cgtactgcca
     4021 gccccaggtg gccagcttcg gctacaccga ggagcaggcg cgcgagcgcg gctacgacgt
     4081 gaaggtggcc aagttcccgt tcaccgcgaa cggcaagtcg cacggtctcg gcgacccgac
     4141 cggattcgtg aagctgatca gcgacgcgaa gtacggcgag ctgatcgggg gtcacctgat
     4201 cgggcccgag gtgaccgaac tgctgcccga gctcaccctg gcccagcagt gggacctgac
     4261 cgtgcacgag gtcgcgcgca acgtgcacgc gcacccgacc ctcggcgagg cggtcaagga
     4321 agcgatccac ggcctggccg gccacatgat caacttctga cgatggcacg cgtactggtg
     4381 atcgggctgg atcccgccaa gatcgagggc tgggatccgg cgcccgtcca ggcggcgatc
     4441 gcccgaggtc aggcccggtt cgacgatctc ggcatcgagt ccgacatgtg cctcgtggtg
     4501 cccgacgaga acccggaagc ggtgatcgtc gaggcgctga ccagtgccga gtacgcctgc
     4561 gtggtgatcg gcggcggcat ccgcaagcac gagccgctgc tcgaactgtt cgagaaggtg
     4621 gtgaacctgg tccggcggca cgcgcccggc gcggccatcg ccttcaacag cggccccgag
     4681 gacaccgccg acgcggctca gcgctggttg agctaggact acagggcctt tccggcaaat
     4741 cgtgagccac gctaacgggt cgagcccgct gaacctttta gccgcgctaa cgggttcagc
     4801 gggctcgacc cggttgtagc cctgtcgtac taaacgggcg gcagggcgag ccagtcctgc
     4861 caggtgatgt cgcggcccag gtagcgggcc ttctggaagg gccagtcggc ggcgatccat
     4921 tgcggcacca gcgcgtcgag cgcgcgttcg acctcgccgc cgaccaggtc gtccaccacc
     4981 caccaggcga tctcgccgtc cgagccggtg cgctcgggcg ggtcgatgta gacgcagccg
     5041 aggatcgccg tctccgcctc gtccagcagt gcgtagttga acgactcgtg cgcggcgatc
     5101 tccttctcgt gccgcagcag gtcgatccgg tcctcttcgt aggtcatcgt cgccgtcggc
     5161 caaccccagg ccgggccgaa gatctcccac aggcgctccc gcgagcccat cacggcgggg
     5221 tagtcgatcg cggtgtccgc ctcccggatc ggccgcaggt gcagcgcggt tccgggcacc
     5281 gggacgtgca cggggtggac gaagtcgtca ggcagccagc tcatgcggcc gagactacgt
     5341 ccgccctcgg cgtcaccggg gcgcgtgctt ggcttcgtcc agcttctcct ggttgtactg
     5401 gtagtcgatg gagtccgcgt acgccttctt gctccactgg tcgaagccct cgctgaactg
     5461 aatgtccccg gtgaccgcgc cgacgatccc gccgatgatc ccgccgaccg ggccgtactc
     5521 cctgttcccc tcggcggcac ccgcggtgct tccgaccgcg gctccgacgt aacccatgcc
     5581 caccatgccg atgctgcgga tcactccggc ttcgatcgtc tgcttgcctc tggcgacgtt
     5641 gtacagctcg tcgccgacgg tcaggatgtc gccgatgatc gggaccgcct tgccgccgat
     5701 cgccggcgcc gcgaaccggg cgtcggacgg caccgtggcc cgaggccgcc ccggtccttc
     5761 gtagtcggcg aatcccggtg gcaccgcctg ggtcgtgacc ccggacggca gcccccgctc
     5821 cagctgtcgc acgagccaga gcatcatgtc gcggttcgcg ccggaggtct tggccatctt
     5881 gtcgaagtac ggccccagct tcgaggtcga gacggatttc gccgaggcga tctccgtgta
     5941 cgtcctcgcc tcgatgtcca ggtcgttcaa caccgtgact acgcgccgcc gcgccgtgtt
     6001 gtggtggtcg atgcccttga gcaccttctg cgccgcggtc ccgccgacct gccagttgtc
     6061 caggttgaat tccttccgcg gggccagatc gccctgcagg ttcgcgtgtg cctcgtcctc
     6121 tttcttcctg gcgctcttca cgatgtcact gcactcgttg aacaccttga cccgctcgtt
     6181 gaacacgtcg accctggcgt cgtaggcctt gaccccctgg tcgtacgcgg cccggttgtc
     6241 gggggcgaag tcgtctggct tcttcggcgg cgagccgacc atcgccgcgt ggtcgggcgg
     6301 cacgatggtg aagtcggtga cggtcagccc gccggcccgt gccttcgcca gcgcctcgtt
     6361 catggtcttg accacgatgt cgatcgagtc cgcgaagtcc gtcattcccc tcgcgtacaa
     6421 ctcgcaggtc aacgcgaggt cgtcgcagtt gtcgcggggg ccgcgcatga cgtcgatgaa
     6481 cctctgctgc gccggtcccc accaacccgc gcttgccgtc tgcctactgc cctgggcggc
     6541 gttcccggcc tcgtgcgcac ccttgccgag cgccgcgaag tcggccgcca cctgcctgca
     6601 cccaccgata tcgcagacca ccatggtgtt gatgctcatc agttgggcca cttccggccg
     6661 ggcaggtagt tgccccgctc cggcgcgtcc cacagaccac ccgggtcaga ggcctcgccc
     6721 gacggcaact cccgcaggcg catgttcccc gcctgagtgt tctcgatctc gccgtagctc
     6781 ccgaacgtgt agttgatctt gctggcgttg tcctcgagca cctccgccag gaccacacgc
     6841 gcggtgttga ccaatcgcac cgccgcaccg acctgcgcgg aagactgccc cgcgaaggcg
     6901 acacagggct gctgcgcacc catcgcgtgg tccagcgacc tggcggcacc cttgagctgc
     6961 tcggcgatcc ccggcagcac tcccgggtcg aatccgtatc cgtcgggcat gtgtcccact
     7021 cctctcagca cacgtcgcgg tgggcccagt ccacgaccgg cccgctgtat ctgagttcct
     7081 ggtcgagcac cgcgtcgaac agcacgccgt gcgcgcccgc ctcggctgtg acggcgtcca
     7141 ggtcctcggg gttcacgcga atcgccgcct gatgctcgcc gcagcacgcg cgcagatcct
     7201 ccagtgagcc gtacgcgagc agcatcggct cgcccggccg cacggcgtac agctccacct
     7261 gcgcggccct ggcgccgggc acgaccggca gggaggggat ccacgcctcg gtcagcgggg
     7321 ggacgtgctc ggcgtaggcg agcggctcca tctcccggac gtcctgctcg gcgtagcgct
     7381 cgccctccgg gtgccacgcg tcgatcgcga ccagcacggt cgcctccatc ctggcgggca
     7441 gcgcggacag ctcctccttg cgcaggcgca cccacggttg ggccggcccg cacgactcca
     7501 ccagttcccg tggatcggag taggcgaaca gcaggacctc gtgccggtcg gtgcggcgtc
     7561 cctccagacc gccgcctcgc aggctcagca cgagcaactc gtcgtcgccg cgaaggtcct
     7621 ccgcggcgat cagcgtggcg cgctccagcg gtgtcggcac gacctgacgg taaccacggc
     7681 cggcttcgtg gtgtgccgtc cgaacaaccc tcaggcgcgg ctcgattcgg ccgagaaaaa
     7741 tcttccgccg atgtcgatta gttccgatcc ggttcgacgt ctacatagaa acggaactcc
     7801 caccgaccat cggagatcgc gatgtccgcc cagctgctca ccctgccggt cccctcccac
     7861 accactcctg acctgcacgt tccgccggaa cgcctgcacc gggacctggc caccacgctg
     7921 gtcgccgagg acctcgccga gcaggagtgg cggctggact cgcacgagcg gctgacctgc
     7981 tcggagcacg gccagtggct gcaccgctgc gtgcacgcca agccgcacgt caacaagatc
     8041 accggctacc gctggtgccg cccgtgccgc gccgagctgg aggtcgcggt ggacgagatc
     8101 gacggcacgg tcaccgtgca ctgcccgaag tgtgaccgcg gcgccgagac caaggccgac
     8161 ttccagctga tctccgcctg ccggcagtcg ctggacgccg cgcacaccgc ccgagcggcc
     8221 gtcgcggcct gatcgacgcc cggccgcccg gtgggagttc cgtcctaatg ccgagcggcc
     8281 gtcacgagtc tcagtaccga ggacagccac ggcgtgtacg cgtgcgggtc gtccgccatc
     8341 gccgagtgca cgtgcgccgg gtcgagccag gtgtagtcgg acacctcggc cgggtcgggt
     8401 gccggctcgc cgtcggtgag cgtgccgagc agtacgtgat cccattcgtg ctcgacgaag
     8461 ccgctgccgg tgtccgccgc gcgataggtg aacgagccga cctcggtcag ggtggccgtc
     8521 agcccgagtt cctccgcgag ccggccgacc gccgcctcct cgacccgctg ccctggagcg
     8581 gggtggccgc agcaggtgtt cgaccagcgc gaggcgaacc gggtcttcac cggtgcgcgg
     8641 cgctgcagca gcagccggcc gtccgggtcg acgagctgta cggagaacgc ccggtgcagt
     8701 cgtcccggcg cggtgtgcgc ctcggtgacc gtgcacgtgc cgatgccgac gccggtcgcg
     8761 tccaccaact cgacggggag ctgttcgcgt gaatttccca tatagccacc ttgtttgttg
     8821 atttttgtca cccgcggcct cggatggtgt accaaagatc gcgacgaccc gagagtgtga
     8881 cgtgccacag gcagaagggt gcccggccac atggtgcgac ttgtgactcc cgcgcggcct
     8941 ggagccgcgg tctggtggat cccgcgcggc gaacggccgt gggccgatta ttgggtggca
     9001 caagacgcta gccgtcggcg tgatcagcta ctagcctgcc ctcggtcagc gccgactgtg
     9061 acgaactcgt gaattatctg ttcccccgcc ggatacgaca cgaacggacc gaccaatcaa
     9121 ctatgaccac gacccccaac ggtatcgtcc gcaattctta cgaacgcgac gtctggcgtt
     9181 actaccacga aaagcggcag gacatgatca acctgctgcc cggcgaacct gacggcttct
     9241 atcaccacca ttttggtatc ggtgatttcg accgttccgt cgccgacctg ccggaagtgg
     9301 agcgcgagcc gaaggtcttg gcggagatcc atcgactgga gaacgcgctc accgacctga
     9361 tcgtcgacgc gttggacacc gtcggaccgg aaacgcggat cctggacgcc ggctccggcc
     9421 gaggcggaac cagcttcgtg ctgcacgaca ggttcggctg ctcggtcgac ggcgtcaact
     9481 tcgcctctta tcaggtggag ttcgcccagg aactggccaa ggccagggac tgcgcggaca
     9541 aggtgcggtt ccaccagcgg aacatggtgg acaccggatt ccccgacgac tacttcgacg
     9601 tcatcgtgac gaacgagacc acgatgtacg tggacctgcc cgaggcgttc ccggagttcg
     9661 cgcgcgtact caaaccgcac ggccgctacg tgctcatcac ctggtgcatc aacgacgccg
     9721 tctgcgacgg aagttcggac atcgatcaga tcgacaagaa ctacgtcagc aagatgcacc
     9781 cgcgcagcgg ttacttcgcc gaactggcca agcacggatt cgtgcccaac cacgtgttgg
     9841 acttcagtcg ggacgccgtg ccctactggg aactgcgcca gctgtcaaag catcgcaccg
     9901 gaatcgaaga cgcgtatctg tccgcgtatc ggcagaacgc gatccaggaa atcctggtgg
     9961 cgaccgacta cgtgcccacc tccgccgagg ggcgaggctg atgggtcgga cactgtgtgc
    10021 ccaacccgtc aaggaccgcg tcgacgccga gctgatcgcg ttcttcgacg cgaccgcgaa
    10081 ctcgatggaa cccgatgccg ccgaactgct ggtcccgttg cgggcgatgc tgacccgtgg
    10141 caagcacgcg agcaccgcgt tctgccacaa cacctatcgg gcactcggcg gcgatgacac
    10201 cgccgccgtc tggccgaagg tgtgcgccgc gttggaactc gcgcacctgg cgatgctcac
    10261 ccacgacgac gtcatcgacc gctccgccac ccgccgcggc caggacgccg tgcaccgcgc
    10321 ctacgcgagc cagcacctcg cggccgggtg gaccggcgac gccagccggt acggcatgga
    10381 catggcgctg tgcgtcggcg acctgctggt catccagtcc gagacgctga tggactcggc
    10441 cagcccggac accgcgcagg ccaaggccct gatgcgggtg atgcgccaga tgtaccggga
    10501 cgaggtgtac ggcgagaccc tcgaactgcg cgcccagcag gaccgcgtct accagcccga
    10561 ccgctgcgcg aaggtcgccc gctggaagac cggccgctgg atcgcgtcgg tcagcgcctg
    10621 cggtgccgtg tccgcgcacg ccgatccgga aaccgtggcg gtcatggacc agttcggcga
    10681 gctgatgggc ttcgcctacc agatgcgcga cgacctgctc ggggtgttcg gcgactcggc
    10741 ggtcaccggc aagcccacca tggacgactt ccgcgacggc aaacccacgg tgctcatcgc
    10801 gctcgcgatc agccaagcgg acgcagccgg tatcgagacc atcgaggagc tgtacgggaa
    10861 gccgacgctc agcgaggacg acggagacgt cctccgcgcg gtgatcgagg agtcgggcgc
    10921 ggtcaagagg gtggaggaga tgatcaacgc gcacatcggg aaggcggagg aactgctgtc
    10981 cgcacaccgt gccgagagct ccgacctgct cgccctcgcc cacgcggcgc tgaaccggtc
    11041 gtcctgagag gcacgctcga tggaggaccg gattcgccgg acgcacgagc tgatcggacc
    11101 ggccctgcgg gcccaggtgg acgcgatgca cccggacctg gcgcgcgcgg tgggctatca
    11161 cctcggatgg tgggacgagc acggcacgcc gtcgcgggcc tacggcaagg cgtcccgcgc
    11221 gacgatctgc ctcgccgcgt gcaccgcgct cggcggccgg cagtccgacg ccgtgcccgc
    11281 ggcggccgcg ctggagatgg tgcaccagca gtcgctgatc cacgacgaca tcatcgacga
    11341 cgacaccctg cgccggggcc ggccctcggc gtggacggcg ttcgggacac cggtcgcgat
    11401 cctcgcgggc gactcgatgg ccggcgccgc gttcgcgctg ctggcagcga aggacggaca
    11461 tgccgccgat gtcctgcgat cggcctatct ccgcgtgtgc gacggccagg ccgccgatct
    11521 ggctctcgaa ggagatctga ccgccacccc ggaggcatac gtggagatgg cgctcggcaa
    11581 ggccggcgcg ctgttcggcg cgtcgaccgc gatcggtgcc gtcatggccg gggccgacca
    11641 ggacaccgtt gagcggatgc ggcaggccgg catcgacatg ggcgtggcga tgcaggtggt
    11701 cgacgacatc cggtccatct ggcagccgag ttcgggcacc ggcaagacca ccaagggcga
    11761 cctggtccgc ggcaagctga cctacccggt gatcgccgcc ctgcggtcgc cggactcgga
    11821 cgagctcgcc gcactcctac gggacccgca ggagtgcgac acggtcaagg cggcggcact
    11881 ggtggaggac ctcggtggcc gggccgacgc cgaggagttc gccgcgcaac gcctgcgcct
    11941 cgcgctgggc gggctggccg ccgtgccgat gagcgacgag ggccgcgaag acctgctgcg
    12001 ggttttcacc tgggcgtccg ccacgcatct gctcacccaa ttctgacaat ctcgaaggga
    12061 gcgtcctcga tgcgcgatgc gatcgaacgg gcggacacga tcgtcgggga gttggacaac
    12121 cggccggtcg ccgggtcggc gtactcgacc gcgtgggccg ccagactcgt ccacgacgac
    12181 ggtcggccgg tgttcgaaca ggcccgcgag tggctgcgaa cccaccagca cgcggacggc
    12241 tcgtggggca gcgctgtacc gaacgcgtac gaccggctgg tgtgcacgct ggccgccgtg
    12301 ctgaccctgt ccgaggtgcc cggcgagtgg gcggccgggg cggtgcgcgc cggggtcgac
    12361 tacctccgcg agcacgcggc ggactggcgg gacgcgcctg ggcagatcat cgggttcgag
    12421 atcgtcgcgc cgtacctggt cgagcaggcg cgcgcggccg gcctgctgga gatcgactcg
    12481 cgcaccgaac tggcgctgct gcgcgaggag aagctcgcgc tcgtgccgga gggtgcgctg
    12541 accagtcagc cgacggcgct gctgtactcg ctggaggcgt tggacgatct ggtctccgtg
    12601 cccgacgtgt tgaagttcgc cgcgccggac ggctcgatgt ccagcaaccc cgccgcgacg
    12661 gccgcggtct gggcggcgac gaaggacccg gcggcgttga catacctgcg ggacgcggcc
    12721 cgatccgccg gtgacggcgg gctgccggag atctatccga tcgacgtgtt cgagccggcc
    12781 tggacgatct acctgctcga tcgggccggc ctgaaaccga gcggcgtgca gcagcacgtc
    12841 gagcgctttc tgcgactgag cggcgaggac ggcgcgccgc tcgggagcag tgcggacttc
    12901 ccgctgccgg attccgactg caccgcactg gtcgcgatcg tcgcgcactc cttcggctac
    12961 gagaccacgc cgctgctgga ggcgctgctg ccgttcgagc gggacgatca tttcgccggc
    13021 ttgccccatg agcggttcgc gccggtgagc ggcaacgcgc acgtgctgga ggcgctttcc
    13081 cagcagccgc accggttcgc cgcacaaatc ggcaagaccc gggacttctt acttgacgcc
    13141 cggcgcgaat ccgcgtggtg gcacgacaaa tggcatttct ccgaccacta cgccaccgcg
    13201 caagccgtgt tcggactcgc cggcgccacc gagccgggca cgctcgcggg gacctggcgg
    13261 tggctgctgg acggccagca cccggacggc tcctggggtg cggccggcgg gcaggccgag
    13321 gacaccgcct acgccgtgct cagcctggac gcactcgcgc cgcaccacgg tccggtgccc
    13381 gaggacacct atcgccgcgc gcacgcctac ctgcgcgagc acctcgacgc gccggactac
    13441 gccgagttgt ggatcggcaa gagcctgtac acgccgccga ccgtcgtgcg cgcggcggtc
    13501 gccgccgcct gggtcatcag cgggcaggcc gacgatgagt gagccgacct acgcgacggc
    13561 cgcgcagtgc gtgcacctgt ccgcgctggg cctggcggcc tgtgcagacc tgcagcgctg
    13621 ggccgccgag gaatggccca ccttcccgca actgcacctg gccggcgctg gctacggcga
    13681 ggcgatggtc gccccgtggg ccacggcgga ccaggtgcgg ctgaccggcc ggatgtgcgt
    13741 gtgggcgcac gcgctggaca aattcgtcga ccgcgagatc accgagcgcg cccaactcga
    13801 cgatttcgtc gaccgctgca ataccgtcgt ccgaacaggc gaacccgatc acggtaatca
    13861 gttgcttcgg attctgtccg actggcagcg ggaattcgcc gagctgccgg actattcgcc
    13921 gctggccgcg gtgtgggagc ggaagttcga ttcctgtctg cgcggccacc agtacaactg
    13981 ggtcgtgggc tcggcgcgcg agcggggcga ggaaccggag gtcgatgtcg ccgcgtacct
    14041 cgcgcactcc gacagcgtcg cggtcggact ggtccaggtg ccgcggtggg tggcctacgg
    14101 cggcgccgaa ctgcccgacc ggttggacgt gctgctcccc gcgctcgacc acatcgcggt
    14161 ggcggtccgg ctggcgaacg acctcgccac catcgaccgg gagcgcgacg agccggggca
    14221 gaacaacatt ctgatgtacg gcgtctcgcc ggactgggtg cgcgccgagt acgtcgaccg
    14281 ggtggcggcg gtccggcggc gcctcgcccc gctcgtcgag gagaacttca tgccggcgat
    14341 cggactcgtc cggctcgccg agtggtccgt cggcgtctac gagcgcaggg acatggcccc
    14401 ggccatgtcg ctccccgcag caggaagtga ggcacgaacc cggtgaacac gcggaatacg
    14461 accccagccg atgtcccggt tcgggatttc aaccatcacg ccgatccgga tctccgtatc
    14521 gacccgttcg ccacattcga ccgattccgc gacgagcggg tgttctggac cccggaactg
    14581 gacggtttct gggttctcac ccgttatgac gacattcgcg cggtattgcg ggacacggag
    14641 cgattctcca acgagagcac cgcgattccg ccgatcgact ggaatggtca gcggctgata
    14701 ccggtcgaac tggatccgcc ggaccacggc aagtaccgca ccctgctcac ccgctatctg
    14761 aacggccccg ccaacgccgt gctcgccacg gccgtggaga aggagtgcct gcggctcgtc
    14821 gagcgtctcg cccccgccgg cgagtgcgaa ctcgtcgggg acttcgcccg caagctgcag
    14881 aacgccctgc tcggtgcgat gttcgacgag ccgggcgagg aggacgacgt gcccgacttc
    14941 gggcggttgt ccgacgacct cgtgcaggcc agcgaaccgg cccgccgcag ccgcgcgatc
    15001 cgcgacatca tggcctacct gcggcgggcc atcgccgggc accagacgcg gcgcaccgac
    15061 agcacctcgc tgatcgcctc cctgtccggc gcggagatcg acggccggcc gctcagtgaa
    15121 tccgagacgc tgaacatggc gttcctgatg accatggcgg ccatcgacac gctgaccagc
    15181 tcgatgagct tcggcttccg ctacctcgcc gagcatcccg cgcaccagcg ccggctcgcc
    15241 gaggaccccg gtgccgccgc cgcggccgcc gacgagttgc tgcggttgca ctcggtggtc
    15301 agcatcgccc gcatcgtcgc gcgtgacacc gagttcgccg gcgtccggat gcgcgccggc
    15361 gagcgggtca tgctcagcct gtcactggcc ggacgtgacc cgcaccagta cccggaggcg
    15421 accaccgcgg acttcgatcg cccgaaccgc gccagccacc tggcgttcgg cttcggcgcg
    15481 caccgctgcg ccggcgcgcg catcgccacc ggcggaatga tcgcggcact gcgcgagtgg
    15541 cacgccgcca ttccggagta ctcggtgcgg ctgggaaccg agctggtcac cggtggcggc
    15601 gcggccgcct cactggaaag cctgccgctg gtctggaaaa cctgacagtc aggcgtcctc
    15661 aatgatcagg tcggcggccc gccagcccag tgcggagacc gggccgttga ggttgccgga
    15721 gaccagagtg gggaacaccg aggcgtcgac gacgcgcagg ttggccacgc cgcgcacgcg
    15781 cagccgcgag tcgaccacgt cgtcgtcgtt cgggcccatc gcgcacgtcc cgacggcgtg
    15841 gtagccggca ctgcccacgg tcagcgcgaa gtcctggatc tcctggtcgg tgtcgacctc
    15901 ggggccgggc agggtttccc gctcgacccg cttggccagc gggccggtgc cgaacaggcc
    15961 gcgcagggtg cggaagatcg ccaccgtcgt ggtgcggtcg tactcggtgt cgaggtagtt
    16021 ggcgtcgatg tccaccggcg cgtcgggatc cgccgaggtg atccgcacgc tgccctcgct
    16081 ggtcggccgc agcgcgtagc cgatgcccat catgccgggc tcgcgttcga tctccagcgc
    16141 cttgccctgc tcccggggcg cgatcgagaa cggcgcgatc tggaactgcg cgtccgggcg
    16201 gtcgaggtcc ggccgggtct tgaagaaccc gacgatctcg aacgcgggcg cggcgagcac
    16261 cccggtctgg ctcgtctggt actcgaccat cgccgcctgc tggccctcgg gagtgctcag
    16321 aatcttgttg tagccgaggt cctcggtgag gcggacctgc atctggaacg cgcggtgctc
    16381 gcgcatccgg gcgccgacat tcgggctgtc caccacgacg tcgacaccgg cttcgcgcag
    16441 cgtctcggcg gggccgacac cggagagctg gaggatcttg ggactggcga gcgcaccggc
    16501 ggcgaggatc acctcgcggg tggccgtggc ctcgaacgcc tcgccgtcct gccgccccag
    16561 cacgccgacc gcgcgaccgt cctcgatcac cacccggtcg accgtcgtgt gcacggcgac
    16621 ggtgaggttg tcccgctcgg cgaccgggtg caggaacgcg ccggccgcgc tgacccgcag
    16681 gccgtcgcgg atcgtggcca tcgtgtagcc gacgcgctcg tcgtcgttct cgttgaggtc
    16741 ctccgcgcgc tgccagccga gctcgccgcc ggcgtcgatc acgtcgtcga gcagcgggtc
    16801 gccctcggtg cgggtggaca cccgcagcgg cccgccggcg ccgcggacgt cggacgcgcc
    16861 gaatggattg tcctcgatct ccttgtaggc ggccagaatg tggtcccagc cccaacccgg
    16921 gttgccgagc cgctccagct cgtcgtagtc ctcgcggctg cctcggttgt agaccatgcc
    16981 gttgaccgag ctggacccgc cgagcgtctt gccgcgcagc cagacctctg gctcgcccgc
    17041 gggtccgaac gggtgggtcg ggtggaacca catggcgtcc gggtcgccga acagttgggc
    17101 ggccgcgccc ggtatggaga tcatcggatt ggtgtcctgg tcacccgcct cgatcagcag
    17161 cacggagacg tccgggtccg cggagagacg attggccagc gcacatcccg ccggcccggc
    17221 acccacgatg acgtagtcga actctgccac ggagaactcc cgtcgttgct ggatcatgac
    17281 ctgccgacgt ccggcaggcg gcacgctagt acgcctgatc gactggcggt agaactattt
    17341 tcgaaccgca cctgtagtgg gttcacacca cagcgttaac ccgatagtgt gccgacattg
    17401 atcgatccgg gcggtgggta gatcaggtta ggagtccggt tgtgcggctt gctcccggaa
    17461 agagcagcgg gcttcggagc atcaggctgc ggatgctcgc catcgtgctc attccgagtg
    17521 cggcgctgtt gatcctcggt gtcggcgcgt ccggctacct ggtctatcag ggatccacgg
    17581 cccaggattg ggccacgacc atgcgggaaa ccgcgccacc cggcacccag ttcgtcgcgg
    17641 aggtcgagga agagcgccgg ctgagcctgt tccgcctcgg cggggagcgg gcggccgccg
    17701 agccgctcgc ggcgcagcga cagcggctcg acacgtccct gctgggcatg cagtcgatgt
    17761 cggccagctt ctccaagctg aacccggacg cgctgaaaga aggcaacgag gccttccaga
    17821 aggtgctcgc gatgctcccg acgatccgtc agggagtcga cgcgggccag gcgcctccga
    17881 tggacgtcta cgcgtactac agcgggttga ccgaggccgt ccggatgggt gtgcagggcc
    17941 tggcgaagac cgcgccggac ccggtgaccg cggtggagga gtcgacctcg gtcaccgtgt
    18001 tcaccgccgc ggacgccatg tccaggggcc acgccctcgc ggtcggcgcg gtggtcaacg
    18061 gcgggctgtc cgtcgcggag taccaggagt tctcccggca ggtcggccgc taccgcacca
    18121 cgatggaatc cacggtcccg ctgctgagca agccgctgca ggagcgctac gccacgctgg
    18181 ccgcgagcga ccagtggaag cggctcggcg aggtggagaa cgcgctgctg ctgcgcgggc
    18241 cccggccggg tccggcgcgc gacctgcggc cgttgccgat cagcattccg gactggcagg
    18301 cctcggcgtc ccacgtgaac accgagctgc tcgacatgta ctccgagcac cacagctacg
    18361 cccagtccgt cgccgaggag accggcgagc gcaccttcgt caactcgctg ctggccggcg
    18421 gcgggatcct gctgctcacg atcatcgcga cctgggtcgc catcgtgctg tccaaccggg
    18481 tggtccggcg gttgaagaag ctgcgcgccg agacgctgga gctggccgac aagcgcctgc
    18541 cgatgatcgt cgaccggttg cgcggcggcg agcagatcga cgtcgcccgc gaggtgccgc
    18601 cactggacca cggcgcggac gagatcggcc aggtcgccga ggcgttcaac aaggcccagc
    18661 gcaccgcggt catcgcggcc gcgcaggagg ccgagatcca gaacggcgtc aaggcggtgt
    18721 tcctcaacat cgcccaccgc agccaggtcg tggtgcgccg ccagctcgag gtgctggaca
    18781 aggccgaacg cgagcaggag gaccccgacc agctcgagtg gctgttccag ctcgaccacc
    18841 tggccacccg cgcgcggcgc aacgcggaga acctgatcat cctcggcggg gagcagccgg
    18901 gtcgccagtg gcgcaacccg gtgccactgc tggagatcgt gcgcagcgcg atcggcgaga
    18961 ccgagcagta ccgccgcgtg cagaccggcc ggctgcccga tctggcgatc tcgggggccg
    19021 cggtcgccga cctcatccac ctgctcgccg agctggtgga caacgcgacc cagttctctc
    19081 cgccggactc gcgggtggag gtgcgcggca acacggtggg caagggcgtc gtggtcgaga
    19141 tcgaggacca gggcctcggc atcctcaccg acattcgcga gggcatcaac acctcgctgc
    19201 agaacccgcc ggacttcagc gtgatggcgc tgtccgagga gacacagctg ggcctgttcg
    19261 tggtgtccca gctggccgcg cggcacggca tcagcgtcac gctggtggac tccgcgtacg
    19321 gcggaatccg ggcgatcgtg ctgattcggt cggcgatcat cgcgcaggac ccggacgagc
    19381 cggctcccgc ggagcaaccg caggaaggcg ccaccgagcg ggagccggat atcctgcggc
    19441 ggctgcgaag gctgtcggac tactcggcgc acgagtacta ctcgtcggcg gcgcccaccc
    19501 aggtgctgga cgctccggcg acgagcacgg gttcgacgga agccgacccg gcggtccagt
    19561 ggccgcaaca agaggtatcg aacggtgcgc accactccga ggtcgccgat cagcgtggct
    19621 cggcgccgac agaggtgatc acgggtaacg gccgcaacgg gggcggcgat gcccaacggg
    19681 ccgaggacgg gcggccggaa ctgccgcgca ggcggcggca ggccaatctc gcgccacaac
    19741 tggccagcga aaccgagcta ccggtggagc agagccagac ccagccggac gacgatgccg
    19801 acggcgtctc caccgccgag cgtgctcgcg accggatggc ggcctttcag cggggtaccc
    19861 gggaggggcg ggcggcaccg tgagttggtc gtccgcctga tgttcgtcga gtcgatcaag
    19921 acaggggagc catggagaac tccggcacga ccgatctgaa ctggttgctt gacgacctgg
    19981 tcacgcgggc ggttggtgcg cgacacgcgg tcgtgttgtc caccgacggc ctgtgcgtcg
    20041 gccggtcccg cgacctgaac agggaggaca gcgaacagct ttcggcgatg gcgtcggcgt
    20101 tccagagcct cgccaggggc gtcgggcgcc acttcgaggg cggtgaggtc cggcagacgg
    20161 tcgtcgaact ggacaacgcc tacctcgtgg tgacctcggc gggcaccggc gcctgcctcg
    20221 cgctgatcgc ctccgaggac gccgacatcg gcatgctggc ctacgagatg aacatcatgg
    20281 tcaagaaggt cggcgcttac cttgtggcga agccgcgtgt atccggcttc cacatgtgac
    20341 cgcgcccatg aagcacggtc gggagtcctg gtacgacgac gaggccggtc cgctggtccg
    20401 gccctacacc gtgacgcgcg gtcgtaccag gtcgggtcat ggcctcgacc tggacatgat
    20461 cacgctcgtg gtgagcaacg cgtccggtca caccgtggtg gatccggagt acgcgcagat
    20521 cctgcggatg tgtcggtacc cgctgtcgat cgcggaggtc agcgccaagc tcgggctgcc
    20581 gctggcggtg atcaagatcc tgatcgccga cctgatcgag gacggactgc tgatcttccg
    20641 ttcgcccccc tcgcccctgg acacggagac cccggacatg gacatcctgc aggcggtact
    20701 cgatggcatc cgtaggctct gacccgcgca ccgagccggg actcgggaca tcggcggtca
    20761 aggtgctgat cgccggcggc ttcggcgtcg gcaagaccac gatggtcgcc tcggtgagcg
    20821 aggtggcgcc gctgcgcacc gaggagcgca tcagcgacat gggcgggaag gtcgacgacc
    20881 tcggcggcgt ggagggcaag aacaccacga cggtggcgct ggacttcggc cgcatcacga
    20941 tcaacgaatc gctgatcctg tacctgttcg gcacgccggg ccaggagcgg ttctggttca
    21001 tgtgggacga gctgtccctg ggcgcgctcg gcgcggtggt gctcgccgac acccgcaggc
    21061 tggaccgctg tttcgccgcc gtggactact tcgagcggcg ccagatcccg ttcgtcctcg
    21121 cggtcaacaa cttcttcggc gagcagcgct acaccgtcga tgaggtccgc gacgccgccg
    21181 acctggactc caacgtgccg atcatgcagt gcgacgtgcg ccagcgggag tccagcaagg
    21241 tcgtcctgtc caccctgctg gaacacctca tgacgatggc cgcacaacgc tgacctccgc
    21301 cagggcgact gccgaacacg ccgtgctgtc cgaaacttag cgatcgctcc gttcatgttt
    21361 tgcgtacttt agcccgctaa agtccctcgg ccacggagaa agcccaggtc acgcaagatc
    21421 aataggcagc ggtgaatctg gtccggcggt gtttggggtg ctcgatctcg tccaggagta
    21481 ctaccgcgag gtcctcgatc gagatcgtcg actcgccgtt cgcgtccacg accagctcgt
    21541 cggaccccag ccggtagacg ccggtgcgct cgcccggcac caggttcgca ggcgggctca
    21601 gatacgtcca gtccactgtg gactcacgga ggaccgcgtg ctgttcggcg cacgcgcggg
    21661 cgatgtcggc ggccacctcg ggcaggtatc tccggtcgtc cagcaccagg ccgccgcccg
    21721 gcgcgcgcag ggtggccgcg ccgccgacga gcagcagccg ggtgccggac cgggccacgc
    21781 cggccagcag cgccttcgcg gtctcgacca actcgtgctc gctgccgtcc ggcgggcggg
    21841 tggcgctgat cgcggcgtcg tggtccccgg tcagtcgggc tacatcgtcc acagtggacg
    21901 catcgccccg gacctcgttg gggtgcaacg gtttccgcac gacggcggtc acccggtggc
    21961 cacgggactc ggcttcggcg acgacccgcc ggccgacaga tccacgtgct ccgaaaacga
    22021 cgattcgcat gtcttctcct tgggggtacg ggtccggcgg atgttctgtc cgacgacggc
    22081 gcccaccgcg agcaacgctc cgagggcttg cagggcggtg aggctctggc cgagcacgat
    22141 ccagcccagc gcggtggcca cgagcgggct gagcacgccg aggaacgtga cgttggtcgg
    22201 cgagagcgcg cggatgccgc ggaaccacag cacataggcg agcgccgcgc cgatggttgt
    22261 caggtaggtg tacccggcga tgttgccggc ggtcagcacc ggtggccctc cctcgacgag
    22321 cagggctacc gggagcagta gcagtccacc cgcgacgagc tgccagctcg tggtggtcag
    22381 cggcgactcc ggcgaggtcc accgtttgct cagcaccacg ccgagcgcca tggacagcac
    22441 tccgccgagt gccgcggcca cgcccaggaa atccagccgc gcgtcggcct tgagtaccag
    22501 caggccgacg cccagcacgc cggccgcacc cgcgaccagc gtgcggccgg tcagccgctc
    22561 gccgagcagc ccgaccgaga acgccgcgac gatcaggggt tgcagcgcgc cgacggtcgc
    22621 ggcgacgccg ccgggcagcc ggtaggccgc cacgaacagc agcgccatga agacggccat
    22681 gttgagcgcg ccgagtacca gcgcgcgcca ccaccacacc ccgcgcggca gccgtcgcgt
    22741 gaacgcgagc agcagcagac cggccggcag ggtgcgcagg agcgcggcga gcagcggccg
    22801 gtcgggcggc aggagttcgg tggtgaccag gtaggtggag ccccacacgg cgggcgccac
    22861 cgcggtgacc agcagcacgg tcgttcgatt gcttagcact aaactaatgt acctcagcgc
    22921 taaactagtt tgtcaagatg tcttaccgct aaactgttcg cgtggcggat cacgttgaca
    22981 tggtgttgcg gcagtgggcg gacgagcggc cagacctgga cgcctcgccg atggcgatcg
    23041 tgggccggct gagcaggctg tcccgcatgg tcgacaacgc gttgaccgac tacttcgccg
    23101 agcatgggct ggaccgggcg tccgtcgacg tgctgttcac cctgcgccgc agcggctcgc
    23161 cgtaccggct gacaccgtcg gagctgacgc gctcctcgat ggtcacgtcc ggcgcgatca
    23221 cccagcggct cgaccggctg gaggcgcgcg ggctgatcgc caggaggcgc agcgaggccg
    23281 acggtcgcgg tgtggtcgtc gcgctcaccg acgaagggca cgagctgacc gaggcggtgc
    23341 tgcccgggca cctcgacaac gagcgcaggc tgttcgacgc gctcactccc agccagcgtg
    23401 acacgttcgc tcgaacgctg cgcaaagtgc tggaatcgtt gggggacaag acggattgac
    23461 ttctagttag ctagaggttc taccgttgtg atcatgactg ttgtactgct tggcagagag
    23521 ccgaaagtcg tcaagagtgt cgggtccgaa ctgcgtgcgc gaggcttctc cgtcgtcgag
    23581 tgcacgggtg acgacgaggc cgtggccgcc gtcgattccg gcgacgccac cgccatcgtg
    23641 atcggtggcg gcgtcgaacc ggcgagccgc gagcgggtca cctcggccgc gcgggcgcac
    23701 ggcgtcgcgg tggtggccgg tcggcgcggc gacggtccgc tggccaccta cgtcgacgag
    23761 gtgctggtgc ccgagctgcg cgaggtcagc gcggcataac gctgcttcgc ctgtccgcgc
    23821 gacgagcggg attaagcccg ctgaaacctc ttcacgtcca gcgcgcccgt ggcgctagat
    23881 gcggggatga atcgggcaaa caaccacaac tcgggccgcc aagcgggaat gagcccgctg
    23941 aatcccgtcc gtggagcggg attgagcccg ctgaatcccg ctcgcgttcg gcgtgcggtt
    24001 ggcgaggtca gtgcggggtg aggctgtttc gcctgtcccg cacggcattt cgggtgtcct
    24061 cgccgaccag atcggcgttg atcatcgcgg ccgccttggc acccccggcg gcggcggtga
    24121 tcacctgcgc gctgggatcg gtgacgttgc cggcgaccca cacgcccggc acgctggtgc
    24181 ggccggtctc gtccgaggcg acgtagctgc cgccccacgg gtgctcggtc gtggtgatcc
    24241 cgagcccggc gagcacgccg gcgcgggcca cgaatttcgg cgtgacgaac agcgcgcgca
    24301 ggccgatcac ctcgccggtg cgcagccgca cgccggccag ctcgtcggcc accacctcca
    24361 gcccggccac ctcgccgtcg accacggaga tgtcgcgcgc ggcgaactgc tcccactcct
    24421 cgtcggtggg ctcggcgccg gtgtgc
//
