LOCUS       NZ_SGWQ01000007        10945 bp    DNA     linear   CON 10-APR-2024
DEFINITION  Herbihabitans rhizosphaerae strain DSM 101727 Ga0310478_107, whole
            genome shotgun sequence.
ACCESSION   NZ_SGWQ01000007
VERSION     NZ_SGWQ01000007.1
KEYWORDS    WGS; RefSeq.
SOURCE      Herbihabitans rhizosphaerae
  ORGANISM  Herbihabitans rhizosphaerae
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Herbihabitans.
REFERENCE   1  (bases 1 to 340414)
  AUTHORS   Goeker,M.
  TITLE     Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing
            the most valuable type-strain genomes for metagenomic binning,
            comparative biology and taxonomic classification
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 340414)
  AUTHORS   Goeker,M., Huntemann,M., Clum,A., Pillay,M., Palaniappan,K.,
            Varghese,N., Mikhailova,N., Stamatis,D., Reddy,T., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-FEB-2019) Prokaryotic Super Group, DOE Joint Genome
            Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.12.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 226.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004216555.1-RS_2024_04_10
            Annotation Date                   :: 04/10/2024 19:27:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,690
            CDSs (total)                      :: 6,628
            Genes (coding)                    :: 6,561
            CDSs (with protein)               :: 6,561
            Genes (RNA)                       :: 62
            rRNAs                             :: 3, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2 (5S)
            tRNAs                             :: 54
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 13 of 67
            Pseudo Genes (incomplete)         :: 59 of 67
            Pseudo Genes (internal stop)      :: 5 of 67
            Pseudo Genes (multiple problems)  :: 9 of 67
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:31:17
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 292683
            Orig. end                         :: 303628
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            SGWQ01000007.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..10945
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="butyrolactone"
                     /region_number="2"
                     /rules="AfsA"
                     /tool="antismash"
     cand_cluster    1..10945
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="AfsA"
                     /kind="single"
                     /product="butyrolactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10945
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:5945](+)"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5945
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="1"
     gene            639..1553
                     /locus_tag="EV193_RS21825"
                     /old_locus_tag="EV193_107255"
     CDS             639..1553
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007030137.1"
                     /locus_tag="EV193_RS21825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_107255"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_130346045.1"
                     /transl_table=11
                     /translation="MIEVRELTKRYGDTVAVRELSFTVKPGQVTGFLGPNGSGKSTTMR
                     AILGLDRPTSGVAMVNGRPYATLRKPLHEVGALLDAGAVHGGRTAEMHLRCVARSNGIG
                     RARVTDVLERVGLAGVARKRIGGFSLGMRQRLGIGAALLGDPGVLMFDEPVNGLDPEGI
                     RWIRELMRALAAEGRTVLVSSHLMSEMALTADHVVVIGRGQLITETSMAALSEDFRRDV
                     LVRTPRADELRGALSTAGASVHSGPDGELAVRGMDAVAIGDLALRAGIAVHELTPRSAS
                     LEEAYMELTDESVEYRAQAGRAS"
     misc_feature    complement(658..671)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.91"
                     /tool="antismash"
     gene            1550..2317
                     /locus_tag="EV193_RS21830"
                     /old_locus_tag="EV193_107256"
     CDS             1550..2317
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EV193_RS21830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EV193_107256"
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_130346046.1"
                     /transl_table=11
                     /translation="MNDVLASEWLKLRSLRSSVNLLIGPLAGLVAGAVITALMAADWDS
                     SPEMRDKFAAGDAGLLAQPVTQVCLATLAILVITGEYATGMIRTSLVAAPNRLQVLAAK
                     ALVVSGVTLVAGQVISFAGFWASRLIVGDRPPPFGFSGSAADAVPLVVADGLVITVISL
                     VALGLGTVIRSTAGALVSVFVLLFVLPMVAMALPSSVGNVLASLMLRNLAPQLAGVPQS
                     EAVLSQPGAVAVAVGYVVVALGAAAVVLRRRDA"
     gene            2496..3317
                     /locus_tag="EV193_RS21835"
                     /old_locus_tag="EV193_107257"
     CDS             2496..3317
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009156115.1"
                     /locus_tag="EV193_RS21835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_107257"
                     /product="AfsR/SARP family transcriptional regulator"
                     /protein_id="WP_130346047.1"
                     /transl_table=11
                     /translation="MDIDVLGPLAVRIDGVSVTPTAAKPRKVLAMLAVHADEVVPAPSL
                     FEELWGDAPPRTATTTVQTYVLHLRNLITTALRGNADREYADAKQVLATRPGGYVLNTG
                     GGTVDVREFDRLAAAGHRARELGDYEDAARSFTEALSTWRGKALVDVQVGALLEVEVHR
                     LEEARLNVLDRRIDADLRLGRHHQLLGELSALVSRHRTHEGLYAHLMLAMYRSGRRGEA
                     VEVYRKLRACLAHDLGLEPSPTLRRLHRSMLDADPRLHEYVTVEPPVGAAV"
     misc_feature    2520..2522
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    3228..3230
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            3325..3960
                     /locus_tag="EV193_RS21840"
                     /old_locus_tag="EV193_107258"
     CDS             3325..3960
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF041196.1"
                     /locus_tag="EV193_RS21840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_107258"
                     /product="ScbR family autoregulator-binding transcription
                     factor"
                     /protein_id="WP_130346048.1"
                     /transl_table=11
                     /translation="MTKQARSEQTRALLLNAAADLLSKDGYAASSMEDISKAAGVTKGA
                     LYFHFSGKDKVCAAVQSEAVSILRTFIAELETGRTSALQSLIDLTHTMVRWLDTEPVIA
                     ASFRIGRECGSTDDSFLTFSRAWFAEVRRALRVAKKNQELSEDVRMDVAVVMVAVMCLG
                     IEMLATTSSRPAKPSESLAGMWTLILPEIADDETLAGLDAFGSSNVDR"
     misc_feature    3361..3363
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    3727..3729
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(4160..4795)
                     /locus_tag="EV193_RS21845"
                     /old_locus_tag="EV193_107259"
     CDS             complement(4160..4795)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009082160.1"
                     /locus_tag="EV193_RS21845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_107259"
                     /product="ScbR family autoregulator-binding transcription
                     factor"
                     /protein_id="WP_130346049.1"
                     /transl_table=11
                     /translation="MARQERAERTRNVILDAAAEAFDEYGFVGASLSDILATAGVTKGA
                     LYFHFSSKEELASALIEEQFSVWGPFAATDRPGLQTVIDLTHNMAMNLMLSVRVRAAIR
                     LVIEHGSFASPAIDAYRSWTDLVERCMVAAQATGDLRKEVQPDDLAMYVIGSFTGVQLR
                     SQVLTGRADVRQRVTDMWQFLLPGIVPPRRLTKFNPTGTVDYEVAASA"
     misc_feature    complement(4805..4818)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 18.76"
                     /tool="antismash"
     misc_feature    complement(4908..4922)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.58"
                     /tool="antismash"
     gene            5001..5945
                     /locus_tag="EV193_RS21850"
                     /old_locus_tag="EV193_107260"
     CDS             5001..5945
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     butyrolactone: AfsA"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF041195.1"
                     /locus_tag="EV193_RS21850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_107260"
                     /product="ScbA/BarX family gamma-butyrolactone biosynthesis
                     protein"
                     /protein_id="WP_130346050.1"
                     /sec_met_domain="AfsA (E-value: 1.5e-22, bitscore: 73.7,
                     seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAMIEKDDATGVLPDAGPVLFEQTIPRHLVHRAAVAEVFVTDLH
                     VTNENTFHVGAQWPRGHSFFGPRTTASHDPLIFAETIRQAALLVSHAALGVPKSDRFLL
                     HDMSVSVDMVGLRTADRPVDIVVVVRAHDIRRRGDSIGGIRLEFSCYRDGRKIGTAGLG
                     WSCASAAGYRRVRGDRFSATPYQATLLPAVKPQLVGRDRPEDVVLAETPLHNVWSLQAN
                     PGHPVMFDHPVDHVPGMVLLEAARQATLLTVGKANAVPRAMEFTFRRFVEFEDPCLVIA
                     DDQGRTRGGRRLGVTFEQCGRTVATGTMELADA"
     misc_feature    complement(5013..5027)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.64"
                     /tool="antismash"
     misc_feature    5040..5042
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    5259..5261
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    5655..5657
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            5938..6918
                     /locus_tag="EV193_RS21855"
                     /old_locus_tag="EV193_107261"
     CDS             5938..6918
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (11-194). E-value:
                     1.7e-13. Score: 42.2. Matches aSDomain:
                     nrpspksdomains_EV193_RS21855_NAD_binding_4.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018681339.1"
                     /locus_tag="EV193_RS21855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_107261"
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="WP_130346051.1"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 4.2e-07,
                     bitscore: 23.6, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 7e-12, bitscore:
                     39.2, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 8.8e-13, bitscore:
                     42.2, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPELAGASPVLVTGATGFVGTAVVRELLRRHDGGALIRVLCRREP
                     PAWMREAGIAVVHGDLAEAATLDGACDGVSTVLHLASRIGGDLEACTAVNVDGTRALLE
                     QARRAGVSRVVQLSTTGVYGDGVHRGASESLLAPSPVSVTSRTRLAAERMTRAAGGIVL
                     RPHLVYGEGDKWVVPTVLRWLRAVPGWADGGVARSSMVAVSDLASVIAALACMRWGPRR
                     GAVFHVNHPRPVSMRELVTALCGHLDLPLPDLDLTADAHRMLTRSALPSLTDHQFSMLA
                     QDHFYDSTRIWSFTGVEPGPGLATRLPDAIPWYRDVLSGKATAAV"
     misc_feature    5947..5949
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     aSDomain        5971..6519
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EV193_RS21855_NAD_binding_4.1"
                     /evalue="1.70E-13"
                     /label="EV193_RS21855_NAD_binding_4.1"
                     /locus_tag="EV193_RS21855"
                     /protein_end="194"
                     /protein_start="11"
                     /score="42.2"
                     /tool="antismash"
                     /translation="VTGATGFVGTAVVRELLRRHDGGALIRVLCRREPPAWMREAGIAV
                     VHGDLAEAATLDGACDGVSTVLHLASRIGGDLEACTAVNVDGTRALLEQARRAGVSRVV
                     QLSTTGVYGDGVHRGASESLLAPSPVSVTSRTRLAAERMTRAAGGIVLRPHLVYGEGDK
                     WVVPTVLRWLRAVPGWADGG"
     misc_feature    6975..6993
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 25.19"
                     /tool="antismash"
     gene            6993..8015
                     /locus_tag="EV193_RS21860"
                     /old_locus_tag="EV193_107262"
     CDS             6993..8015
                     /GO_process="GO:0015891 - siderophore transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1033: iron
                     compound ABC transporter, periplasmic"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015803774.1"
                     /locus_tag="EV193_RS21860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_107262"
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="WP_130346052.1"
                     /transl_table=11
                     /translation="MQRRSFGRAVLAVVAGLVLASCSGGTATSGNQSAGQAPPAQADGG
                     RTFPVKVTHKYGTTEVRKADKIVTLGLSDHEIVLALGAKPVGVVDWFKERPFGKFPWQK
                     AKWGDTEPQIVGERDDYNMERIIALQPDLIIAQYSGMKKEQYDALSRLFPVVAQPVGYA
                     DYAAPWQEMTRVVGRAMAKSDQAEALIKGIDDRYAAVRERNPKFGQKTIVVGDSFQPGA
                     YAAFAAHDPKAGFMVELGFKTPPRIAAAPKEQNVVEVGSEGLGLFEADVAVWLTSSEDA
                     VRRTQSDPLYRKLKVATEGRDLFIPYETPPIGAALSFGTVLSIPYAIDNAVPLLAKAVK
                     "
     gene            8018..9013
                     /locus_tag="EV193_RS21865"
                     /old_locus_tag="EV193_107263"
     CDS             8018..9013
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1011: transport
                     system permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015803764.1"
                     /locus_tag="EV193_RS21865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_107263"
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="WP_130346053.1"
                     /transl_table=11
                     /translation="MIRTARVAGLVAALGVLAVAVVLSLWLGSTDIAFGDALAVLWRDD
                     GSTDAVTIRQVRAPRAALAILVGIALGLSGAVMQALTRNPLAEPGLLGVTMGSSTAVVV
                     AIGFFGLSGVLAHVWFAIIGAALAATVVYLLGATGRSIVTPDRIVLAGAAVTAVLLAFN
                     SAVLLLDPLAFNEFRFWNVGSLAGRRADVLAVVAPFVLAGTVLTLALAHALNALALGED
                     AGRGLGANVTLVRVLAAIALTVLCGAATAAAGPIVFVGLAVPHVARMIAGPDQRWVMAY
                     SVVLGPILMLVGDVIGRVIIAPREMQVGIVIAFIGAPVFLALCLRSKVSL"
     gene            9010..10008
                     /locus_tag="EV193_RS21870"
                     /old_locus_tag="EV193_107264"
     CDS             9010..10008
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1011: transport
                     system permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF013219.4"
                     /locus_tag="EV193_RS21870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_107264"
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="WP_165401453.1"
                     /transl_table=11
                     /translation="MKALRARPVAVGALLAVVIVCVGVYALTSGEVRLSVPDVLDSLLG
                     NGNPVSDTVVLRLRLPRVLTAILVGAALAVSGAVMQSLTRNVLGSPDFLGIVYGATTGA
                     LITIIWIGGTLAEISFGAFVGGMATAMLMYVLLYRRGLHGFRLVLVGVGLSAMLVAFNQ
                     YLITRAVLYEALAAQAWMTGSLNLRGWNDVLAMGVVLAVLLPAALLGARALGALELGEE
                     MAAGLGVPVRAARAAFLAISVALAAVATAVTGPIVFVALIAPQVARRLTGSQGPGLLPA
                     ALLGATLLLAGDVAVQRLFPTSQLPVGIATSMVGGLYLAWLLSSEWRQRSR"
     gene            complement(9960..10382)
                     /locus_tag="EV193_RS21875"
                     /old_locus_tag="EV193_107265"
     CDS             complement(9960..10382)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010692662.1"
                     /locus_tag="EV193_RS21875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_107265"
                     /product="DUF5313 family protein"
                     /protein_id="WP_165401454.1"
                     /transl_table=11
                     /translation="MSHKRPDPVRWLWYQYAGTLPPRYREWVLFDGTCRTWLARVFLRG
                     FVQIAPVLGALLAILVLIGGAWPIALGSVLLGLLVSLRFTAAYAVESVDHRLAKNGYPQ
                     GHGTAVRRALDADANAGRAKRYRERWRHSDDNNQAK"
     misc_feature    10378..10389
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.21"
                     /tool="antismash"
     gene            complement(10388..10906)
                     /locus_tag="EV193_RS21880"
                     /old_locus_tag="EV193_107266"
     CDS             complement(10388..10906)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016001.4"
                     /locus_tag="EV193_RS21880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_107266"
                     /product="nitroreductase family deazaflavin-dependent
                     oxidoreductase"
                     /protein_id="WP_130346055.1"
                     /transl_table=11
                     /translation="MADEPAFPEVRWGTTDNPVARAAAAFGATKPGSWLIRTLTPVDRK
                     LLERSKGKYGILGAFSAPTLLLTTTGRKSGLPRRQPLLHYREGNRAYVVGSNFGQQHHP
                     AWTGNLLADPEAVVTLAGKEIPVRATLLDGEERDRVFAEFVKRAKAYDVYRERTTREIR
                     VFRLDPEQR"
ORIGIN
        1 gtaggcccgc cgctgccgcg ccccgacgcc gaatgcccag gtcgcgccga acgtcgcgca
       61 ggtcaccagg aaccagggga gcgtctcgtc ccacggctgc ggcgccacgg tctcgccggc
      121 gatcaccacc aacccgaccg cgatcaggca ccccgccagc gcggtggtgg ccctcgcgtt
      181 gacgaccgtg acggtgtaca gcatcagcgc gaccgcgagg tacaccggga tggccgcgta
      241 gatcggcacg atgccggtcg tggtggcgac ggccgcgatg ccgaacacga tcgtgaacgc
      301 gggcatcggc cacttgcgcc gtaccgcgat cggcagtccc acggcaagcc cgacgaacca
      361 ggacagccac agcggctcgt gcaagccggt ggggcgcggc gtctcgctgg ccgccacgac
      421 cacggcgagc gccatgacga ccgcgaccat cgcgtcgatg gcgtacaggt gcgcgtcacc
      481 gaatcgcctg ccgaacgggt tctccacggg ccgaccgtat ccgctcgact cgcgcacggc
      541 gtcggagcgc ggtgggtcag accggggtat gagccgctcg cccgggtccg agctgtggtc
      601 cgatgtggac actcgggtga gcggcgatcg ttgtggccat gatcgaagta cgcgagctca
      661 cgaagcggta cggcgacacg gtggccgtcc gcgaactgtc cttcaccgtg aaacccggac
      721 aggtgaccgg gttcctcggc ccgaacgggt ccggcaagtc gaccaccatg cgcgcgatcc
      781 tcggcctcga ccggccgacc tcgggcgttg cgatggtcaa cggccggccg tacgcaacgt
      841 tgcgaaaacc gttgcacgaa gtcggtgcgt tgctcgacgc gggcgctgtg cacggcgggc
      901 gcaccgccga gatgcacctg cgttgcgtcg cgcggagcaa cggcatcggc cgggcgcggg
      961 tcaccgacgt gctggagcgg gtgggcctcg ccggtgtcgc gcgcaaacgg atcggcggct
     1021 tctcgctcgg catgcggcaa cggctcggca tcggagcggc gttgctcggc gatcccggtg
     1081 tgctgatgtt cgacgagccg gtgaacgggc tggacccgga aggcatccgg tggatccgcg
     1141 agttgatgcg cgcgctggcc gccgaggggc gcacggtgct ggtgtccagc cacctgatga
     1201 gcgagatggc gctgaccgcc gaccacgtcg tggtgatcgg ccggggacaa ctgatcaccg
     1261 agacgtcgat ggccgcgctg tccgaggact tccgccgcga cgtgctggtg cgcacgccga
     1321 gggcggacga gctgcgcggt gcgctcagta ccgccggtgc gtccgtccac agtggaccag
     1381 acggcgagct cgcggtgcgc ggcatggacg ccgttgcgat cggggacctg gcgttgcgcg
     1441 ccgggatcgc ggtgcacgag ctgactccgc gcagtgcctc gctggaggag gcgtacatgg
     1501 aactgaccga cgagagcgtg gagtaccgcg cgcaggctgg gagggcgtcg tgaacgacgt
     1561 gctggcatcg gagtggctga agctgcgctc gctccgatcg tccgtgaacc tgctgatcgg
     1621 cccgctggcc gggctcgtcg cgggcgcggt gatcaccgcg ctgatggccg ccgactggga
     1681 cagctcgccg gagatgcggg acaagttcgc ggccggtgac gcgggcctgc tggcccagcc
     1741 ggtcacccag gtctgcctgg ccacgctggc gattctggtg atcaccggcg agtacgcgac
     1801 cggcatgatc cgcaccagtc tggtcgccgc gccgaatcgg ctccaggtgc tcgccgccaa
     1861 ggcgctggtc gtctccggtg tgacgctggt ggccggccag gtgatctcgt tcgccgggtt
     1921 ctgggcgagc cggctgatcg tcggggaccg cccgccgccg ttcggtttca gcggttccgc
     1981 ggccgacgcc gtaccgctgg tggtcgccga cgggctcgtg atcacggtga tcagcctggt
     2041 cgcgctcggc ctcggcacgg tcatccggtc cacggccggc gcgctggtgt cggtgttcgt
     2101 gctgctgttc gtgctgccga tggtggccat ggcgctgccc agctcggtgg gcaacgtgct
     2161 cgcctcgctg atgctgcgca acctcgcgcc gcagttggcc ggcgtcccgc agtcggaggc
     2221 ggtgctctcg cagccgggtg cggtggccgt cgcggtgggc tacgtagtgg tcgcgctcgg
     2281 tgccgcggcg gtcgtgttgc ggaggaggga cgcgtgaggc gcccgggtgc tctggggttc
     2341 gtcgccggcg tttccggtgg tcgagttcgc gatgtgaaag attaggtagg ggcgtcccct
     2401 aggccattga caaaccggtc ggtcggtttt gtatccttgg tgggacgaac gggtcgcaca
     2461 ccaggcgggc cgccgtccga ggcaggggag acgacgtgga tatcgacgtt ctcgggccgt
     2521 tagcggtgcg tatcgacggt gtgtcggtga ccccgaccgc cgcgaagccg cgaaaggttc
     2581 tcgcgatgct cgccgtccac gccgacgagg tcgtgccggc cccatcgctg ttcgaggagc
     2641 tgtggggaga cgcgccgccg cgcacagcga cgaccacggt gcagacctac gtcctgcacc
     2701 tgcgcaacct gatcaccacg gcgctacgcg ggaacgccga ccgggagtac gccgacgcca
     2761 aacaggtgct ggctacccgt ccgggcggtt acgtgttgaa caccggcggc ggcacggtcg
     2821 acgtgcgcga gttcgatcgg ctcgccgccg ccgggcaccg cgcccgcgaa ctcggcgact
     2881 acgaggacgc ggcgcggtcg ttcaccgagg cgctgtccac ctggcgcggc aaggcgctgg
     2941 tcgacgtgca ggtcggtgcg ctgctcgagg tggaggtcca ccgcctcgag gaggccaggc
     3001 tcaacgtgct ggaccgcagg atcgacgccg atctgcggct cggccggcac caccaactgc
     3061 tcggcgagct gtccgcgctg gtgtcgcgac accgcacgca cgaaggtctg tacgcgcacc
     3121 tgatgctggc gatgtaccgg tccgggcggc gtggcgaggc ggtcgaggtg tatcgcaagc
     3181 tgcgcgcgtg cctggcccac gacctgggcc tggagccgtc gccgacgtta cgacggctgc
     3241 accggtcgat gctcgacgcc gaccccaggc tgcacgagta cgtgaccgtc gagccgccgg
     3301 tcggcgccgc ggtctgacct gggcatgacc aagcaggctc ggtcggagca gaccagagcg
     3361 ttactcctga atgccgcggc cgacctgctc agcaaggacg gttacgccgc ctccagcatg
     3421 gaggacatca gcaaggcggc gggcgtgacc aaaggcgcgc tgtacttcca cttctccggt
     3481 aaggacaagg tgtgcgcggc cgtgcagagc gaggccgtgt cgatcctgcg cacgttcatc
     3541 gccgagctcg agaccggccg cacgtcggcg ctgcagtcgc tgatcgacct gacccacacg
     3601 atggtgcgct ggctggacac cgagccggtg atcgcggcta gcttccggat cgggcgcgag
     3661 tgcggctcga cagacgacag ctttctcacc ttctcgcgcg cctggttcgc cgaggtcagg
     3721 cgcgctttac gggtggcgaa gaagaatcag gagctgtccg aggacgtgcg catggacgtc
     3781 gctgtggtaa tggtggctgt gatgtgcctc ggtatcgaga tgctcgcgac gacatccagc
     3841 agaccggcca agccctcgga gagcttggcc ggtatgtgga cgctcatcct gcccgagatc
     3901 gccgacgacg agacgctcgc cggcctcgac gcgtttggat cgtccaatgt cgacagatag
     3961 aagccggttt cggagttgcg tgggtggtcc ggtagggcac gcccaggcgg cgatctacgg
     4021 cgttggcgtc cgctcgagta tgcccaatac gagtcgcgaa cgccgccttg tagctcatcc
     4081 acctggacgc gcccgggtgg tcaccctgcg aggacggggc aggtggcacc tcgagacaag
     4141 gcctagccgt gcgcccctgt caggcgctgg ccgcgacctc gtagtcgacc gtgccggtcg
     4201 ggttgaactt ggtcagccgg cgcggcggga cgatgcccgg cagcaggaac tgccacatgt
     4261 cggtgacgcg ctggcggacg tcggctcgcc cggtgaggac ctgggatcgc agctgcacgc
     4321 cggtgaacga accgatgacg tacatcgcca gatcgtccgg ctggacctct ttgcgcaggt
     4381 caccggtggc ctgcgcggcc accatgcagc gctccaccag gtcggtccag ctccggtagg
     4441 cgtcgatcgc cggcgaggcg aacgagccgt gctcgatgac cagccggatg gccgcccgga
     4501 cgcgcacgct cagcatgagg ttcatcgcca tgttgtgcgt caggtcgatg accgtctgca
     4561 ggccggggcg gtcggtggcc gcgaacggcc cccacaccga gaactgctcc tcgatgagtg
     4621 cggaggccag ctcctccttg gaggagaagt ggaagtacag ggcgcccttg gtgacgccgg
     4681 cggtggcgag gatgtcggac aggcttgcgc cgacgaagcc gtactcatcg aaggcctcgg
     4741 cggcggcatc gaggatcacg ttccgcgtcc gttccgctcg ctcctgtcga gccacggtca
     4801 ctccttagct tcggtcgacg gttcagtcgc cgcatcccct gtcagtcgac catagcggcc
     4861 ggctgtcagg gcccacccac cgagtgtagc ccaagtttgc cgtaaggaaa gatccgaaaa
     4921 aaaccgggta gtaggtatgg tttttgccct ggggttccga tttactacgt acagggtctt
     4981 catcgctgac ggaggtagtc atgaccgcca tgatcgagaa ggatgacgcc actggggtat
     5041 tacccgacgc gggaccggtg ctcttcgagc agacaatccc gcgccacctg gtacatcgtg
     5101 ccgctgtggc agaggtcttc gtaaccgatc tgcacgttac aaacgagaac acgtttcatg
     5161 tgggggcgca gtggccgcgg gggcacagct tctttgggcc gaggaccacg gcctcccatg
     5221 atccgctgat cttcgcggag accattcggc aggcagcgtt actcgtttcg cacgccgcac
     5281 tcggcgtgcc gaagagtgac cgcttcctgc tgcacgacat gtcggtctcg gtcgacatgg
     5341 tcgggttgcg caccgccgac cgcccggtgg acattgtcgt cgtcgtgcgt gcgcacgaca
     5401 ttcggcgcag gggtgattcc atcgggggaa tcaggctgga gttcagttgt taccgcgacg
     5461 gtcgcaagat cggcacggct gggcttggct ggagctgcgc gtcggccgct ggataccggc
     5521 gggtgcgggg agaccgtttc tccgcgacgc cgtaccaggc gacgctgctg cccgcggtca
     5581 agccgcagtt ggtcggcagg gaccgtccgg aggacgtggt gctggcggag accccgctgc
     5641 acaacgtctg gtcgttacag gccaatccgg gccacccggt gatgttcgac cacccggtcg
     5701 accacgtccc cggaatggtt ctgttggagg cagcacgaca ggcgacgctg ctcaccgttg
     5761 gcaaggccaa cgcggtgccg cgcgccatgg aattcacctt ccgccggttc gtcgagttcg
     5821 aggacccgtg cctggtgatc gccgatgacc aaggccgtac caggggcggc cgacggctcg
     5881 gtgtcacctt cgagcaatgt ggtcgcacgg tcgcgacggg cacgatggaa ctggcggatg
     5941 cctgagttag ccggtgcgtc tccggtcctg gtgaccgggg cgaccgggtt cgtcggcact
     6001 gccgtcgtgc gcgagctcct gcggcgtcac gacggcggag cgctcatccg agtgctctgt
     6061 cgtcgtgagc cgccggcgtg gatgcgcgaa gccggcatcg ccgtcgttca tggcgacctc
     6121 gccgaggcgg ccacgctgga cggtgcgtgc gacggcgtgt cgacagtgct gcacctcgcc
     6181 tcccggatcg gcggcgatct ggaggcgtgc acggccgtca acgtcgacgg cacccgggcg
     6241 ctgctcgaac aggcgcggcg ggccggggtg tcccgggtgg tgcagctgag cacgacgggg
     6301 gtgtacggcg acggcgtgca ccgcggtgcg agtgagtcgc tgctggcgcc gtcgccagtc
     6361 tcggtgacga gccggacgag gttggccgcc gagcgcatga ccagggcggc cggaggcatc
     6421 gttcttcggc cgcacctggt ctacggcgag ggcgacaagt gggtggtccc gaccgtgctg
     6481 cgctggttgc gggcggtgcc gggctgggcc gacgggggag tcgcgcgctc gtcgatggtg
     6541 gccgtgtccg acctggcgtc ggtgatcgcg gcgctcgcgt gcatgcggtg ggggccgcgg
     6601 cggggcgcgg tgttccacgt caaccacccg aggccggtca gcatgcggga actggtgacc
     6661 gcgctgtgcg ggcacctgga tctgccgctg cccgatctcg acctgaccgc cgacgcgcac
     6721 cggatgctca ccaggtcggc gctgccgtcg ctcaccgacc accagttctc catgctggcc
     6781 caggatcact tctacgacag cacgcggatc tggtcgttca ccggggtgga accgggaccc
     6841 ggcctcgcca ctcggctgcc ggacgcgatc ccgtggtacc gcgacgtgct gtccggcaag
     6901 gcgaccgccg ccgtctgaca tcgcgagtcc cgcgctgtgc accggtgagt cccgcgctgt
     6961 gcaccaccgg acggtatggt taggctgccc taatgcagcg aagatcgttc gggcgagccg
     7021 tgctcgcggt ggtggcgggc ctggtactgg cgtcgtgcag cggtggcacc gccacctcgg
     7081 gcaaccagag cgcgggccag gccccacccg cgcaggccga cggcggccgc acctttccgg
     7141 tgaaggtcac ccacaagtac ggcaccaccg aggtgcgcaa ggccgacaag atcgtcaccc
     7201 tcggcctgtc cgaccacgag atcgtgctcg cactcggtgc caagccggtc ggcgtcgtcg
     7261 actggttcaa ggagcgcccg ttcgggaagt tcccgtggca gaaggcgaag tggggcgaca
     7321 ccgagccgca gatcgtcggc gagcgcgacg actacaacat ggaacggatc atcgcgctgc
     7381 agccggacct gatcatcgcg cagtacagcg ggatgaagaa ggagcagtac gacgcgctgt
     7441 cgcgcctctt cccggtggtg gcgcaaccgg tcgggtacgc cgactatgcc gcgccgtggc
     7501 aggagatgac ccgcgtggtc ggccgcgcga tggccaagtc cgaccaggcc gaagcgctga
     7561 tcaagggtat cgacgaccgg tatgccgcgg tgcgcgagcg gaacccgaag ttcgggcaga
     7621 agacgatcgt cgtcggcgac agcttccagc cgggcgccta cgccgcgttc gccgcgcacg
     7681 acccgaaggc cgggttcatg gtcgaactgg gcttcaagac gccgccgcgg atcgccgccg
     7741 cgcccaagga gcagaacgtg gtcgaggtcg gctccgaggg gctgggcctg ttcgaggccg
     7801 acgtcgccgt gtggctcacc tcgtcggagg acgccgtgcg gcgcacccag tcggatccgt
     7861 tgtaccgcaa gctgaaagtg gcgaccgagg gccgtgatct gttcatcccg tacgagaccc
     7921 cgccgatcgg cgcggcgttg tccttcggca ccgtgctgag catcccgtac gccatcgaca
     7981 acgcggtgcc gctgctggcc aaggctgtca aatagggatg atccgcacag cacgtgtcgc
     8041 gggactcgtc gcggcgctcg gggttctggc cgtcgcggtg gtgctgtcac tgtggctcgg
     8101 ctcgaccgac atcgcgttcg gcgacgcgct cgccgtgctc tggcgcgacg acgggtcgac
     8161 cgacgcggtg accatccggc aggtgcgcgc gccgcgtgcg gcactggcga tcctggtcgg
     8221 catcgcgttg gggctctccg gtgcggtgat gcaggcgctg acccgcaatc cgttggcgga
     8281 acccggtttg ctcggcgtga cgatgggttc ctcgacggcc gtcgtggtgg ccatcgggtt
     8341 cttcggcctg tccggtgtgc tcgcgcacgt gtggttcgcg atcatcggcg ccgcgctggc
     8401 cgcgaccgtg gtgtacctgc tcggcgccac cggccggtcg atcgtcacgc cggaccggat
     8461 cgtgctcgcc ggcgccgcgg tgaccgccgt cctgctcgcg ttcaactcgg ccgtgctgct
     8521 gctggacccg ttggcgttca acgagttccg cttctggaac gtgggatcgc tggccggccg
     8581 gcgggccgac gtgctggcgg tggtcgcgcc gttcgtgctc gccggcaccg tgctcaccct
     8641 cgcgttggcg cacgcgctga acgcgctggc actgggcgag gacgccgggc gcgggctcgg
     8701 ggccaacgtg acgctggtgc gggtgctggc ggcgatcgcg ctcaccgtgc tgtgcggcgc
     8761 ggcgaccgcg gcggccgggc cgatcgtgtt cgtcgggctg gcggtgccgc acgtggcgcg
     8821 catgatcgcc gggccggacc agcggtgggt gatggcgtac tcggtggtgc tcgggccgat
     8881 cctgatgctg gtcggcgacg tgatcggccg cgtgatcatc gcaccgcggg agatgcaggt
     8941 cggcatcgtg atcgcgttca tcggcgcacc ggtgttcctg gcgctgtgcc tgcgcagcaa
     9001 ggtgagcctg tgaaggccct gcgcgcccgg ccggtggcgg tcggcgcgct tctggcggtc
     9061 gtgatcgtgt gcgtcggggt atacgcgctg acctccggcg aggtgcggct gtccgtaccg
     9121 gacgtgctgg actccttgct gggcaacgga aatccggtgt ccgacacagt ggtgctccga
     9181 ctgcggctgc cccgtgtgct gaccgcgatc ctggtcggtg cggcgctcgc ggtgagcggt
     9241 gcggtgatgc agagcctgac ccgcaacgtg ctcggcagcc ccgacttcct cggcatcgtg
     9301 tacggcgcga ccaccggtgc gctgatcacg atcatctgga tcggcggcac gctcgcggag
     9361 atctcgttcg gcgcgttcgt cggcgggatg gccaccgcaa tgctgatgta cgtgctgctg
     9421 taccggcgcg ggctgcacgg cttccggttg gtactggtcg gcgtggggct ctcggcgatg
     9481 ctggtcgcgt tcaaccagta cctgatcacc cgcgcggtgc tctatgaggc gctggcggca
     9541 caggcctgga tgaccggcag cctcaacctg cgcggctgga acgacgtgct ggccatgggt
     9601 gtggtgctcg ccgtgttgct tccggctgcg ctgctcggtg cccgcgcgct gggcgcgctg
     9661 gagctcggcg aggagatggc ggccggtctc ggcgtaccgg tgcgggccgc acgtgccgcg
     9721 ttcctggcga tcagcgtggc gctggccgcg gtggccacgg cggtgaccgg gccgatcgtg
     9781 ttcgtcgcgc tcatcgcacc gcaggtggca cgcaggctga ccggttcgca ggggcccgga
     9841 ttgctgccgg ccgcgctgct gggcgcaacg ttgcttctcg ccggcgatgt tgcggtgcaa
     9901 cgactgttcc ccacatcgca acttccggtc ggaatcgcaa cgtcgatggt gggcgggctc
     9961 tacttggcct ggttgttgtc gtcggagtgg cgccagcgct cccggtagcg cttggcccgg
    10021 ccggcattgg catcggcgtc gagcgcgcgc cgcacggcgg tgccgtggcc ctgcgggtag
    10081 ccgttcttgg ccagccggtg gtcgacgctc tccaccgcgt acgcggccgt gaaccgcagg
    10141 ctcaccagca gcccgagcag caccgagccg agcgcgatcg gccacgcccc gccgatcagc
    10201 acgagtatcg ccagcaacgc gccgagcacc ggtgcgatct ggacgaaccc gcgcaggaat
    10261 accctggcca gccaggtgcg gcaggtgccg tcgaagagca cccactcgcg atacctcggc
    10321 ggcagtgtgc cggcgtactg gtaccagagc cagcgcaccg ggtcgggacg cttgtgcgac
    10381 aacggtttca gcgttgctcg gggtcgagcc ggaacacccg gatctcgcgc gtggtgcgtt
    10441 cgcggtacac gtcgtatgcc ttggcacgct tgacgaactc ggcgaacacc cggtcccgct
    10501 cctcgccgtc gagcaacgtc gcgcgtaccg ggatctcctt gccggcaagg gtgacgacgg
    10561 cctccgggtc ggccagcaga ttgccggtcc acgccgggtg gtgctgctgc ccgaagttgc
    10621 tgcccaccac gtacgcgcga ttgccctcgc ggtagtgcag cagcggctgc cggcgcggca
    10681 ggccggactt gcggccggtc gtggtgagca gcaacgtcgg cgcgctgaac gcgccgagaa
    10741 tcccgtactt gcccttgctg cgctccagca gcttgcggtc caccggcgtg agcgtcctga
    10801 tcagccagga accgggcttg gtcgcaccga acgcggccgc cgccctggcg accgggttgt
    10861 ccgtggtgcc ccaccggacc tcgggaaacg cgggttcgtc agccatcgtg agcctctcag
    10921 atgagtacac cgggattgag gattc
//
