LOCUS       NZ_SGWQ01000002        17891 bp    DNA     linear   CON 10-APR-2024
DEFINITION  Herbihabitans rhizosphaerae strain DSM 101727 Ga0310478_102, whole
            genome shotgun sequence.
ACCESSION   NZ_SGWQ01000002
VERSION     NZ_SGWQ01000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Herbihabitans rhizosphaerae
  ORGANISM  Herbihabitans rhizosphaerae
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Herbihabitans.
REFERENCE   1  (bases 1 to 816207)
  AUTHORS   Goeker,M.
  TITLE     Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing
            the most valuable type-strain genomes for metagenomic binning,
            comparative biology and taxonomic classification
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 816207)
  AUTHORS   Goeker,M., Huntemann,M., Clum,A., Pillay,M., Palaniappan,K.,
            Varghese,N., Mikhailova,N., Stamatis,D., Reddy,T., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-FEB-2019) Prokaryotic Super Group, DOE Joint Genome
            Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.12.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 226.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004216555.1-RS_2024_04_10
            Annotation Date                   :: 04/10/2024 19:27:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,690
            CDSs (total)                      :: 6,628
            Genes (coding)                    :: 6,561
            CDSs (with protein)               :: 6,561
            Genes (RNA)                       :: 62
            rRNAs                             :: 3, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2 (5S)
            tRNAs                             :: 54
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 13 of 67
            Pseudo Genes (incomplete)         :: 59 of 67
            Pseudo Genes (internal stop)      :: 5 of 67
            Pseudo Genes (multiple problems)  :: 9 of 67
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:31:17
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 17891
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            SGWQ01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..17891
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..17891
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..17891
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="True"
                     /core_location="[6931:7891](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      6932..7891
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    97..112
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.18"
                     /tool="antismash"
     gene            402..1253
                     /locus_tag="EV193_RS05560"
                     /old_locus_tag="EV193_1021"
     CDS             402..1253
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010693389.1"
                     /locus_tag="EV193_RS05560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_1021"
                     /product="sporulation protein"
                     /protein_id="WP_130342932.1"
                     /transl_table=11
                     /translation="MVFKKMMQKFGVGGPSVDTVLDDPHCVPGGRLTGEVRLVGGEADA
                     AIEHIALSLTVQGGRGGRSQLELHRVVVAEAMTLAAKEQREIRFTLEVPWETPVTEVSG
                     QQLPGMELGLRTELSIAKAVDKGDLDPVFVAPLPSQDAVLDAIGVLDFQFNGATVMPGK
                     QTPVQAMVFFPPPNRPVPEVMLVMIAGADGLTVIMETTNGVGIGHTDAAHDEAVDWPAK
                     ITEWLDQLAANPHLAHGYDDDEYGGGRRGPGMGGMVAGAAGGVVGGMMLGEMLDGDDGG
                     FF"
     regulatory      1351..1452
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(1372..1385)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.64"
                     /tool="antismash"
     gene            1606..2895
                     /gene="glyA"
                     /locus_tag="EV193_RS05565"
                     /old_locus_tag="EV193_1024"
     CDS             1606..2895
                     /EC_number="2.1.2.1"
                     /GO_function="GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_function="GO:0070905 - serine binding [Evidence IEA]"
                     /GO_process="GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (76-322). E-value:
                     9.2e-11. Score: 33.4. Matches aSDomain:
                     nrpspksdomains_EV193_RS05565_Aminotran_1_2.1"
                     /codon_start=1
                     /gene="glyA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003090672.1"
                     /locus_tag="EV193_RS05565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_1024"
                     /product="serine hydroxymethyltransferase"
                     /protein_id="WP_130342933.1"
                     /sec_met_domain="Aminotran_5 (E-value: 2.3e-06, bitscore:
                     22.4, seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.4e-09, bitscore:
                     33.3, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTAPHIESTLHAPLSTVDPEVAGAVRAELVRQQSTLEMIASENF
                     APVAVLEAQGSTLTNKYAEGLPGRRYYGGCEHVDVIETLARDRVKALFGAEHANVQPHS
                     GASANAAAMFALLQPGDTILGLDLAHGGHLTHGMRINFSGKLYNVVPYRVHDETGIVDM
                     AEVERLTLEHRPKLIIAGWSAYPRQLDFAEFRRIADLVGAYLMVDMAHFAGLVAAGLHP
                     NPVPHADVVTTTTHKTLGGPRGGVILCRSELAKKINSAVFPGQQGGPLEHVIAAKAVAF
                     KIAAGEEFRERAERTVAGARTLAARLAEQDCREAGVKVLTGGTDVHLVLVDLVESTLDG
                     QQAEDRLHTIGITVNRNAVPNDPRPPMVTSGLRIGTPALATRGFREADFTEVADVIAEA
                     LISDFDEQVQQRLSARVSRLADEHPLYPDL"
     aSDomain        1834..2571
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EV193_RS05565_Aminotran_1_2.1"
                     /evalue="9.20E-11"
                     /label="EV193_RS05565_Aminotran_1_2.1"
                     /locus_tag="EV193_RS05565"
                     /protein_end="322"
                     /protein_start="76"
                     /score="33.4"
                     /tool="antismash"
                     /translation="HVDVIETLARDRVKALFGAEHANVQPHSGASANAAAMFALLQPGD
                     TILGLDLAHGGHLTHGMRINFSGKLYNVVPYRVHDETGIVDMAEVERLTLEHRPKLIIA
                     GWSAYPRQLDFAEFRRIADLVGAYLMVDMAHFAGLVAAGLHPNPVPHADVVTTTTHKTL
                     GGPRGGVILCRSELAKKINSAVFPGQQGGPLEHVIAAKAVAFKIAAGEEFRERAERTVA
                     GARTLAARLAEQDCREAGVKVLTG"
     gene            2906..4288
                     /locus_tag="EV193_RS05570"
                     /old_locus_tag="EV193_1025"
     CDS             2906..4288
                     /EC_number="4.3.1.17"
                     /GO_function="GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_process="GO:0009063 - amino acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005153270.1"
                     /locus_tag="EV193_RS05570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_1025"
                     /product="L-serine ammonia-lyase"
                     /protein_id="WP_130342934.1"
                     /transl_table=11
                     /translation="MAISVFDLFSIGIGPSSSHTVGPMRAARMFTDTLAEQGLLERTAH
                     VHVELFGSLGATGHGHGSDKAVLLGLEGERPEDVDTDSVPVRVAAIKEHKRLRLAGAHE
                     INFDVDTDLVMHRRKTLPLHPNGMTYLARDTRGRLLGEHTYYSVGGGFVVRPPEDGSDE
                     GPTITEDTTALEYPFRTGMELLAHCAETGLSIAAIMRRNELAWRTEEEINSGLLNIWRV
                     MRACVARGCETDGVLPGGLKVPRRANALYEKLSTEDSSRDPLYVMDWVTLFALAVNEEN
                     ASGGRVVTAPTNGAAGIIPAVLHYYERFVHDASDDGVVDFLLTAGAIGVILKETGSISG
                     AEVGCQGEVGSACAMAAAGLVAVRGGSPAQIENAAEIGLEHHLGLTCDPVGGLVQIPCI
                     ERNAVGSTKAIHAARTALRGDGTHIVSLDKAIKTMRETGADMHTKYKETARGGLALNVI
                     EC"
     gene            4373..4669
                     /locus_tag="EV193_RS05575"
                     /old_locus_tag="EV193_1026"
     CDS             4373..4669
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015785656.1"
                     /locus_tag="EV193_RS05575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_1026"
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="WP_130342935.1"
                     /transl_table=11
                     /translation="MLAVTQAAADAITSLTAGDGEAGNGGLRFSVHEEHEAGASLAMEV
                     ANAPQEGDAVVTAEPNANVYLEPKAAAYLEDKLLDVQPDDQGQLSFSLRDNKV"
     gene            complement(4666..6423)
                     /locus_tag="EV193_RS05580"
                     /old_locus_tag="EV193_1027"
     CDS             complement(4666..6423)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EV193_RS05580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EV193_1027"
                     /product="hypothetical protein"
                     /protein_id="WP_130342936.1"
                     /transl_table=11
                     /translation="MAPLTAIAIVVGTIPFAAHAWAAMRGYFAHDDFLITFLAERGNPV
                     DFGYLFQDYNGHLAPGLFALAWVVTWLAPLSYPAAVLPILIMQAATSILLWRLLVRLFT
                     ARPAILVPFAAVTFSPLILFTTLWWAYAAQFVPYLLAMVGALLAHTRHVQTGERRQAIV
                     AAVWVLVGLAFYEKAVLIPVLMFGITTALAPHGRARLLWTVRQYWRLWLGYGVLIGAYA
                     GLYLGLTEGQRAGNDIGGRLELVKRMVLDTLLPGLYGTDLHPAAGGSAGVLPPATAWQV
                     VTIVASVGLIVGGLVVGRGRAALAWLLLAGYVAVGVALVAVARLHLVGPVIGTDGRYVA
                     DIVPVAALCAAIAFLRPSTSEQAPPRRHGLPLPARLLVAAVVAALAAGAMSSFLRLAPA
                     LRFGSAREYVANARAALIDDPGIVIYDRSVPEDVMISWFGPNARPSRVIGLLPGPPRFN
                     RPTDALYLLDDNGTPRPLTSLTNTVTGARGPVPDCGWSVNEQITGIQLNGPIIARQVLK
                     LEYYTARAGAGTITVGGQSTKVDFKPGLQELYLVLDHADGSAQSVDVSRAQPGPPVCVA
                     GVTIGEPDV"
     misc_feature    complement(5503..5505)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(6525..6538)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.46"
                     /tool="antismash"
     tRNA            6620..6693
                     /anticodon=(pos:6654..6656,aa:Leu,seq:caa)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="EV193_RS05585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="EV193_1028"
                     /product="tRNA-Leu"
     gene            6620..6693
                     /locus_tag="EV193_RS05585"
                     /old_locus_tag="EV193_1028"
     gene            6932..7891
                     /locus_tag="EV193_RS05590"
                     /old_locus_tag="EV193_1029"
     CDS             6932..7891
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: TS_UbiA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ubiA"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF013226.4"
                     /locus_tag="EV193_RS05590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_1029"
                     /product="UbiA family prenyltransferase"
                     /protein_id="WP_130342937.1"
                     /sec_met_domain="TS_UbiA (E-value: 7.8e-107, bitscore:
                     352.2, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="ubiA (E-value: 1.2e-27, bitscore: 92.7,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAESAVPNSGKSDGRPTAFTSKPSATMPKWRHPVRRIGFEFYLSW
                     RFLQSNYPPAVLFSLILTLGAWHISDASFERLLLALVTSLSYSWLFLYVHELPNQIVGA
                     AEDAVNKPNRPIPSGLCTPQQAQRRWYPVVGMYLAVATFLGVLPWAICWIAVVYLYHYT
                     GWHRHWVIKALEPPAGAAVLTAGSWSAATGQITSIAWTWILAYFLFWSGACVLQDQRDV
                     AGDELAGRRTLPMVIGDRASRIAGAAFLGVLPATLVAPMTIWAPKTLAVFILDVTYTTI
                     CWLLAWRLLKRRDRISDDLTYRVYAALSCALAASPLLL"
     gene            complement(7990..8439)
                     /locus_tag="EV193_RS05595"
                     /old_locus_tag="EV193_10210"
     CDS             complement(7990..8439)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020421090.1"
                     /locus_tag="EV193_RS05595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_10210"
                     /product="hypothetical protein"
                     /protein_id="WP_242613168.1"
                     /transl_table=11
                     /translation="MTADIDAMAEWSAWCPFDQACLEATRAPGVYMARTGSDGPIVYVG
                     MAGKRKGKGIRGRLYIYSSGKAAVSGLGEAAFNRALADPKWVRERLALLESGEVHSAKQ
                     WARAAIDHLDLYVRWTSTGDRANALALERAVITAMHGLPLWNVRR"
     misc_feature    complement(8374..8376)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(8403..8418)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.97"
                     /tool="antismash"
     gene            complement(9062..9235)
                     /locus_tag="EV193_RS33150"
                     /old_locus_tag="EV193_10212"
     CDS             complement(9062..9235)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EV193_RS33150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EV193_10212"
                     /product="hypothetical protein"
                     /protein_id="WP_165401249.1"
                     /transl_table=11
                     /translation="MLDIAHDTVRAWKQLRGTATGASGEVLHADIARILWEHRVLPTQL
                     CERLRRDPIRGF"
     misc_feature    9477..9491
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.51"
                     /tool="antismash"
     gene            complement(9478..9777)
                     /locus_tag="EV193_RS05605"
     CDS             complement(9478..9777)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EV193_RS05605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_130342939.1"
                     /transl_table=11
                     /translation="MNDDEPVAGGFRAHPGTPATRRWTPEEMRAARPMPTPEPPPAQPR
                     DLRQRALLEVLDRLAESGSVTLEDVATAFNLDQSVVRSSLAEARQLIATWHLRP"
     misc_feature    complement(10108..10126)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 23.58"
                     /tool="antismash"
     misc_feature    complement(10193..10207)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 18.42"
                     /tool="antismash"
     gene            10385..11143
                     /locus_tag="EV193_RS05610"
                     /old_locus_tag="EV193_10213"
     CDS             10385..11143
                     /EC_number="3.4.21.-"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012318.4"
                     /locus_tag="EV193_RS05610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_10213"
                     /product="trypsin-like serine protease"
                     /protein_id="WP_165401250.1"
                     /transl_table=11
                     /translation="MGKLFFLDATTNIDYRCSASVVVAPNKRTVLTAAHCLFDPSRQVG
                     YVDHFFAPAYVDGNAPYGVWDMAEYIVHDKWVNEGKLHFDYGFMRMTRDDGVHIQDVVG
                     ALGFAWNQTNGFIDAMGYPANPPYDGERQKRDFTNSTIVDFANDGGGVLEGWFDEIISD
                     FGGGSSGGPFVRDYNPQNRLGFARGVNSFRIPDRPYVYSAYFDGDAKVGKDFAGESGTG
                     TQTLRASRWAPEGVGPLTTRATTPGTTWCP"
     misc_feature    complement(11274..11288)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     gene            11288..11443
                     /locus_tag="EV193_RS34540"
                     /old_locus_tag="EV193_10214"
     CDS             11288..11443
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013741.4"
                     /locus_tag="EV193_RS34540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_10214"
                     /product="CNNM domain-containing protein"
                     /protein_id="WP_341273139.1"
                     /transl_table=11
                     /translation="MPPLEFLAPAAEPVAIAVVTLLLAFITLVFGELAPKRLAMQHALR
                     WALVVA"
     gene            complement(11746..12507)
                     /locus_tag="EV193_RS05620"
                     /old_locus_tag="EV193_10215"
     CDS             complement(11746..12507)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF044697.1"
                     /locus_tag="EV193_RS05620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_10215"
                     /product="MvdC/MvdD family ATP grasp protein"
                     /protein_id="WP_130342941.1"
                     /transl_table=11
                     /translation="MTVVIFAERADATIDAVVHELRRRDVPVFLADPNWFPDQLVLDAE
                     LSDAAWSGWLCTAGQSVVLQDIRSIWCRERTILPVSAELSFNGVLAALDHVLWVNHPIR
                     AADAASRPLQLATAVGSGLQVPATLVTNSPEAARWFTNGTHDLDQVSSTLTEFQDPVET
                     AHEAHIIAIGDHTFTLASHEWIVTPPSVERALRRYMNHLGLTYAAFAFTIDHSGHWWFH
                     SSDADQFDRLNTHPNAPLIDTFTDLLTAADT"
     gene            complement(12504..12818)
                     /locus_tag="EV193_RS05625"
                     /old_locus_tag="EV193_10216"
     CDS             complement(12504..12818)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EV193_RS05625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EV193_10216"
                     /product="hypothetical protein"
                     /protein_id="WP_130342942.1"
                     /transl_table=11
                     /translation="MRRRLEDYANPPDVDLRDVAALTTSRCSTLKRAAQGDLVRTGDLI
                     ADTRRRLPAHLAIAADTLIGDGLLMITKCALDEPLERLETTATGRAALCRLASNRVPRR
                     "
     gene            13386..14246
                     /locus_tag="EV193_RS05635"
                     /old_locus_tag="EV193_10218"
     CDS             13386..14246
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040183.3"
                     /locus_tag="EV193_RS05635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_10218"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_130342944.1"
                     /transl_table=11
                     /translation="MDSPTLQRRRLAKALKRAREAAGMTQEQAGKAIDGAKSKISRVEA
                     AQSGFRVTDLNVLIELYGVDEVTAARMRELARAGRRRGRWSAYRNVTPDWFTDYLDLED
                     DASTIRWYKPEVVPGVLQTEAYIRAVFTTAAPRRADDEVERLVRVRLERQAVLDRRRTQ
                     SHFILSESVLRRVVGNPTLMANQALHIAEIAEYSNVDVQILPFNAQTYCPASVVFTMLR
                     FDDNPSTDVVYLEDYTDADYLDDEAPVRAYTDLWNRLSAAALGQVESQELLREIAGEHK
                     HPKPK"
     gene            14257..14517
                     /locus_tag="EV193_RS05640"
                     /old_locus_tag="EV193_10219"
     CDS             14257..14517
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020669636.1"
                     /locus_tag="EV193_RS05640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_10219"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_130342945.1"
                     /transl_table=11
                     /translation="MNTPDLSRFAWRKSSYSSDNGGACVEIGLPPEAWRKSSYSEDNGG
                     DCVEVAALADAAAIRDSKNPDGGALMLSGAVWNAFRTAIRA"
     gene            14528..15646
                     /locus_tag="EV193_RS05645"
                     /old_locus_tag="EV193_10220"
     CDS             14528..15646
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016700833.1"
                     /locus_tag="EV193_RS05645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_10220"
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_242613169.1"
                     /transl_table=11
                     /translation="MNEGGSSSRPRLSAAEWLRVRKAPGVRGRELTELAARLYPESQRA
                     PGGHVLAGPGWLLDEPVELDSVRLIWSDIEDPVPSLGPVDHVLPLTDRGERYADYSRAV
                     RDLVRPRLLENRLSYRLLDVQSHNGLALTFGTTTFFEVFNVKQMIAHEFKAEWLSSDGS
                     VPSWDSLPLRSALGDPFDPRRLLMSPGVSTLTIRRDKAGEHRFVLHERDSAKVADGGGL
                     CHVMPAGEFQPSSVAPADVANDFSLWRNIMREFSEEFLGNSEHDEPFRSFERARAEGRF
                     RLWHYGLALEPLELGAVQLTVAVIDDDVFDRLFAHMVTTNDEGRVVGAGGRTDMPFTEE
                     AISRLDPRLSASALTLLRLAWRDRKRLLPPAG"
     gene            15690..16616
                     /locus_tag="EV193_RS05650"
                     /old_locus_tag="EV193_10221"
     CDS             15690..16616
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010696308.1"
                     /locus_tag="EV193_RS05650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_10221"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_130343615.1"
                     /transl_table=11
                     /translation="MRTVLAEVAVDRWAAPTTHQLRIFLVLADELHFGRAAALMFMTQP
                     ALSRQFDALERRLGVQLIARTNRSAELTPAGQAILPEARAVVDAMRGLRRVTRGHLRAV
                     AGHLVIGTAEASMPYTQAILDELRRGHPDLTFEVRPLDLVEQYESLLADEVDAVFCRPP
                     VPEGIATIQLATEPRVVCLSADDPLAELPEIRLARLRDHPVVSYPSECPQVWRDFWTVA
                     VRPDDTAVGSGPVVRDVETLLTTVALGEAIAFLPAVARRFLPRPGIAFLDVIDLSPCLS
                     ALAWHAANGDRPTITALRRAAETARNR"
     gene            complement(16694..17290)
                     /locus_tag="EV193_RS05655"
                     /old_locus_tag="EV193_10222"
     CDS             complement(16694..17290)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EV193_RS05655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EV193_10222"
                     /product="hypothetical protein"
                     /protein_id="WP_130342946.1"
                     /transl_table=11
                     /translation="MWQQSAPSPVEALLSFDLEFKLTPRNTVKTLFAVFCVMFAMTVAP
                     TAASAMKPSTGSGAYCVVVVGKAPADQTSPILSRTCSDDMSVATRQAGIAGETLLMEWF
                     WNANNNPPKLTRIHGNYGGCDAVGYRINIYDDWANNVSGFNSLNGCNVVTGYDLALAQG
                     DNQTWSAYKACNCLLQGWVGSKMNDRIESFRIRHG"
     misc_feature    17241..17254
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 16.68"
                     /tool="antismash"
     misc_feature    complement(17249..17251)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(17252..17254)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(17558..17572)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 18.08"
                     /tool="antismash"
     misc_feature    complement(17727..17743)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 22.52"
                     /tool="antismash"
ORIGIN
        1 aaccagacac cccagaatga tactaaccag accacccata ccagtcaatt taacgcggcg
       61 tgttcaacat tccatggaac caacaaagct taactcagtg gtattgacca gaatggaccg
      121 acgcacacca catcatccac tggctcaacg gcggaatcac cagcgaagaa acaatggcac
      181 tactctgccg ataccaccac accgtcatcc acgaacagga ctggcgcatc gtcatgcgcg
      241 acggattccc gtattatatt ccaccgcgct gggtagatcc cgaccagaaa cccatccgca
      301 acaccacgca ggacgttgtt gcttgacgcg ctcggttccg ccatgatcga tttgaacgtt
      361 tcgcccgatt ttcgttgccg tgacaaggag ttcgcgttcg gatggtcttc aagaagatga
      421 tgcagaagtt cggcgtcggc ggcccgtcgg tcgacaccgt gctggacgac ccgcattgtg
      481 tcccgggcgg ccggctgacc ggcgaggtgc ggctggtcgg cggcgaggcc gacgccgcga
      541 tcgagcacat cgcgctgtcg ctgacggtcc agggcggtcg cggcggccgg tcgcaactgg
      601 agctgcaccg cgtcgtggtc gccgaggcga tgacgctggc ggccaaggag cagcgcgaga
      661 tccggttcac cctcgaggtg ccgtgggaga ccccggtgac cgaggtgtcc ggccaacagc
      721 tccccgggat ggagctgggc ctgcgcaccg agttgtccat cgccaaggcg gtggacaagg
      781 gcgacctcga cccggtgttc gtcgcgccgc tgccgtccca ggacgcggta ctcgacgcga
      841 tcggcgtgct ggacttccag ttcaacggcg ccaccgtcat gccgggcaag cagacgcccg
      901 tgcaggcgat ggtgttcttc ccgccgccga accgcccggt gcccgaggtc atgctggtca
      961 tgatcgcggg ggcggacggg ctcacggtga tcatggagac cacgaacggc gtgggcatcg
     1021 ggcacaccga cgccgcgcac gacgaggccg tcgactggcc cgcgaagatc accgaatggc
     1081 tcgatcagct cgccgcgaac ccgcacctgg cgcacgggta cgacgacgac gagtacggcg
     1141 gcggccggcg cggaccgggc atgggcggca tggtcgccgg cgcggccggg ggtgtggtcg
     1201 gcggcatgat gctcggcgag atgctcgacg gcgacgacgg cgggttcttc tgatcccggc
     1261 ttgacgaggc ccctatccgg ctgcggggag tggacgtagc cggtgggggc cacgtagctt
     1321 tgggcacgga caaccgcata tcgggccgga tgaactggag cgggagagcc cccacgcaga
     1381 gtcacctgtg atggggcacc gaaggagcaa cctcccccgg aatctctcag gtacagctac
     1441 cgcttcggtc aggccgctct ggaaagcagg cgccacgcgc gcctcaccca cggtgcaagt
     1501 cgctcgcgca gattcctggg cgacggcgaa gctctcaggt gcccatgaca gagaggggga
     1561 gttccacgcg ggacgacggc gtcccgtggc gaccaaggag ctcccatgac cacggcacca
     1621 cacatcgaat cgacgctgca cgcgccactg tccactgtgg acccagaggt ggccggcgcg
     1681 gtgcgcgccg agctcgtgcg ccagcagtcc acgctggaga tgatcgcctc ggagaacttc
     1741 gcgccggtgg ccgtgctcga ggcgcagggc tccacgctga ccaacaagta cgccgagggc
     1801 ctgcccggac ggcggtacta cggcggctgc gagcacgtcg acgtgatcga gacgctcgcc
     1861 cgcgaccggg tgaaggcgct gttcggcgcc gagcacgcca acgtccagcc gcactccggc
     1921 gcgtcggcca acgccgccgc catgttcgcg ctgctgcagc ccggtgacac gatcctcggc
     1981 ctggacctgg cgcacggcgg gcacctcacg cacggcatgc ggatcaactt ctccggcaag
     2041 ctctacaacg tcgtgcccta ccgcgtgcac gacgagaccg gcatcgtgga catggccgag
     2101 gtggagcgcc tgacgctgga gcaccgaccc aagctgatca tcgccggctg gtccgcttac
     2161 ccgcgtcagc tcgacttcgc cgagttccgc cggatcgccg acctcgtcgg ggcgtacctg
     2221 atggtggaca tggcgcactt cgccggcctg gtcgccgctg ggctgcaccc gaacccggtg
     2281 ccgcacgccg acgtggtcac cacgacgacg cacaagacgc tcggcgggcc gcgcggggga
     2341 gtgatcctgt gccgctccga gctggccaag aagatcaact cggcggtgtt ccccggccag
     2401 cagggcggtc cgctggagca cgtgatcgcg gccaaggcgg tggcgttcaa gatcgccgcc
     2461 ggcgaggagt tccgcgagcg ggccgagcgc accgtggccg gcgcccgcac gctggccgcc
     2521 cggctggccg aacaggactg ccgcgaggcg ggcgtgaagg tgctcaccgg aggcaccgac
     2581 gtgcacctcg tactcgtcga ccttgtcgag tccacattgg acggtcagca ggccgaggac
     2641 aggttgcata ccatcgggat cacggtcaac cgcaacgccg taccgaacga ccctcgcccg
     2701 ccgatggtca cctcggggct gcgcatcggc accccggcgc tggccacccg cggcttccgc
     2761 gaggccgact tcacggaggt cgccgacgtg atcgccgaag cgctgatctc ggacttcgac
     2821 gagcaggtcc agcagcggct gagtgcgcgg gtgagccggc tggccgacga gcacccgctc
     2881 tacccggact tgtgaggacc tgaccgtggc gatcagcgtg ttcgacctgt tcagtatcgg
     2941 catcggcccg tccagctcac acaccgtcgg gccgatgcgg gcggcgcgga tgttcaccga
     3001 cacgttggcc gagcaggggc tgctggagcg caccgcgcac gtgcacgtcg agctgttcgg
     3061 ctcgctcggc gcgaccggcc acgggcacgg cagcgacaag gccgtgctgc tgggcctgga
     3121 gggggagcgg cccgaggacg tggacaccga ctcggtgccg gtccgggtgg ccgcgatcaa
     3181 ggagcacaag cggctgcggc tggccggcgc gcacgagatc aacttcgacg tggacaccga
     3241 tctcgtgatg caccggcgca agacgcttcc gttgcacccc aacggaatga cctatctcgc
     3301 gcgggacacc cgcgggaggt tgctcggcga gcacacgtac tactcggtcg gcggcgggtt
     3361 cgtcgtgcgg ccaccggagg acggctccga cgaggggccg acgatcaccg aggacaccac
     3421 ggcgctggag tacccgttcc gcaccgggat ggaactgctc gcgcactgcg cggagaccgg
     3481 gctctcgatc gcggcgatca tgcggcgcaa cgagctggcc tggcgtaccg aggaggagat
     3541 caactccggc ctgctgaaca tctggcgggt catgcgggcg tgtgtcgcgc gcggttgtga
     3601 gaccgacggt gtgctgcccg gtgggctgaa ggttcccaga cgtgccaacg cgttgtacga
     3661 gaaactgtcc acagaggaca gttcgcggga cccgctgtac gtgatggact gggtgaccct
     3721 gttcgcgctc gcggtcaacg aggagaacgc ctccggcggc cgggtggtca ccgctccgac
     3781 caacggtgcg gccggcatca tccccgcggt gctgcactac tacgagcgat tcgtgcacga
     3841 cgccagtgac gacggggtgg tcgacttcct gctgaccgcc ggcgcgatcg gcgtgatcct
     3901 caaggagacg ggctcgatct ccggcgcgga ggtcggctgc cagggtgagg tcggctcggc
     3961 gtgcgcgatg gcggcggccg gcctggtcgc cgtgcgcggc ggctcgccgg cgcagatcga
     4021 gaacgccgcc gagatcgggc tggagcacca cctcgggctg acctgcgacc cggtcggcgg
     4081 gctggtgcag atcccgtgca tcgagcgcaa cgcggtcggc tcgaccaagg ccatccacgc
     4141 cgcgcgcacc gccctgcgcg gcgacggcac gcacatcgtg agcctggaca aggcgatcaa
     4201 gacgatgcgg gagaccggcg cggacatgca caccaagtac aaggagaccg cgcgcggtgg
     4261 gctcgcgctg aacgtcatcg agtgctaaca gcgctgtgac ctggtgttgt gcgagatacc
     4321 ccaggttgcc cctacggtgg gtaggcaaga gtgaccgacg aatggaggac acatgcttgc
     4381 cgtgacccag gcggccgcgg acgcgatcac gtcgctgacg gccggagacg gcgaggccgg
     4441 caacggcgga ctacggttca gcgtgcacga ggagcacgag gccggggcgt cgctggcgat
     4501 ggaggtggcg aacgctccgc aggagggtga cgcggtggtc accgccgaac ccaacgcgaa
     4561 cgtctacctc gagcccaagg cggcggccta cctcgaggac aagctcctcg acgtgcagcc
     4621 cgacgaccag ggccagctga gcttttcctt gcgggacaac aaggtctaaa cgtccggctc
     4681 gccgatggtc acgccggcca cgcagaccgg cggaccgggt tgggctctgc tcacgtcgac
     4741 gctctgcgcc gaaccgtcgg cgtggtcgag caccaggtac agctcctgca ggccgggctt
     4801 gaagtcgacc ttggtcgatt gcccgccgac ggtgatcgtg ccggctccgg cgcgcgcggt
     4861 gtagtactcg agcttgagca cctggcgggc gatgatcggc ccgttgagct ggatgccggt
     4921 gatctgctcg ttgaccgacc agccgcagtc cggcaccggc ccgcgcgcgc cggtgaccgt
     4981 gttggtcagc gaggtcaacg ggcgcggcgt gccgttgtcg tcgagcaggt acagcgcgtc
     5041 ggtcgggcgg ttgaaccgcg gcgggccggg cagcagaccg atcacgcgtg acggccgggc
     5101 gttgggcccg aaccaggaga tcatcacgtc ttcgggcacc gaccggtcgt agatcacgat
     5161 gcccggatcg tcgatgaggg ccgcgcgggc gttcgcgacg tactcgcgcg cgctgccgaa
     5221 ccgcagcgcg ggggcgaggc gcaggaagct gctcatcgcc ccggccgcga gtgcggcgac
     5281 cacggcggcg accagaagcc gcgccggcaa cgggagcccg tgccggcggg gtggcgcctg
     5341 ttcggacgtc gacggccgca gaaaggcgat cgccgcgcac agggcggcga ccggcacgat
     5401 gtcggcgacg taccggccgt cggtgccgat caccgggccg accaggtgca ggcgtgccac
     5461 cgcgaccagt gccacaccga cggccacgta gccggcgagc agtaaccaag cgagcgcggc
     5521 ccgtccccgc ccgacgacga gcccgcccac gatcagcccg acgctggcca cgatcgtgac
     5581 cacctgccac gccgtcgccg gtggcagcac tccggccgaa ccgccggccg ccgggtgcag
     5641 atcggtgccg tacaggccgg gcagcagcgt gtccaacacc atgcgcttga ccagttcgag
     5701 ccgcccgccg atgtcgttgc cggcccgctg cccctcggtg agccccaggt agaggccggc
     5761 atacgcgccg atcagcacgc cgtacccaag ccacagccgc cagtactgcc gcaccgtcca
     5821 gagcagccgc gcacggccgt gcggcgccag cgccgtggtg atgccgaaca tcagcacggg
     5881 gatcagcaca gccttctcgt aaaacgcgag cccgacgagc acccacacgg cggccacgat
     5941 cgcctgccga cgctcgccgg tctgcacatg gcgggtgtgc gccagtagtg cgccgaccat
     6001 cgcgagtaga tacgggacga actgtgccgc atacgcccac cagagcgtgg tgaacaagat
     6061 cagcggcgag aacgtgaccg ccgcgaacgg aaccaggatc gccggccggg cggtgaacag
     6121 ccggacgagc agccgccaca gcaagattga ggtggccgcc tgcatgatca ggatcggcag
     6181 gacggcggcc gggtagctga gcggcgcgag ccaggtcacc acccaggcca gggcgaacaa
     6241 gcctggagcg aggtgcccgt tgtaatcctg gaagagatag ccgaaatcga ccggattccc
     6301 gcgctccgcg aggaaggtga tgaggaagtc gtcgtgcgcg aagtaccccc gcatggcggc
     6361 ccacgcgtgc gcggcgaacg ggatcgtgcc cacgacgatg gcgatcgcgg tcagcggcgc
     6421 catcggccgg ctcgtcgtcg aagcccgccg aggtggccgc tcgtggaccc tagtcggggc
     6481 gtcgaggctc acccaagctc ctggaaccgt ttgcgctggt acgtcgatca cttgttcgcg
     6541 ccgtgcacct gggtgttaca ccggagcctc gcccacccgc gcaccgccac cggcggatcg
     6601 cgtaaagttc tctcccgtcg cccccgtagc ccaatcggca gaggcaacgg attcaaaacc
     6661 cgtccagtgt gagttcgact ctcaccgggg gcacttacag catccgcgcg aacggtggcc
     6721 ggcgacaggt cagccagaag gatccacctc ggcggggtcg acgacggcgc ctgcggccag
     6781 cacaccatcg cgagtcgtcc acataactgc tcgtgatcaa ctggtggccg cacccgtctc
     6841 cacggtcctc agtcgagaca acaccaagat cctgatgtat tctttcctgg tgagttacac
     6901 tacctgacgc gacgatagtc gagagtttgc gatggccgaa agcgcagtcc cgaactcagg
     6961 taaatcggat ggtcgcccga ctgcgttcac atcgaagcct tcggcaacaa tgccgaaatg
     7021 gcgccacccg gttcggcgaa tcggattcga gttctacctc agctggcgct ttctgcaatc
     7081 taattacccg cctgcggttc tcttttcgct gattctcacc ctcggtgcct ggcatatatc
     7141 agacgcgtcg ttcgaacgtc tcctgctcgc tctcgtgaca tcgctgtcgt acagctggct
     7201 tttcctctac gttcacgaac tgccgaacca aatcgtggga gccgccgaag acgccgtcaa
     7261 caaaccgaac cggccgattc cgtcaggact gtgcacgcca cagcaagcgc agcgacggtg
     7321 gtatccggtt gtcggcatgt atttggcagt ggcgacgttc ctcggcgtgc tgccgtgggc
     7381 aatctgctgg attgccgtgg tttacttgta ccactacacc ggttggcatc gccactgggt
     7441 gataaaggct ctcgaacccc ctgccggagc agctgtgttg acagctggat catggtcagc
     7501 ggcgaccggg cagatcacat cgatcgcctg gacatggata ctcgcatact tcctgttctg
     7561 gagcggcgcc tgcgtcctgc aggatcagcg agacgtcgct ggcgacgaac tcgccggtcg
     7621 ccgaacgcta cccatggtca tcggagaccg cgccagtcga atcgccggtg ccgcattcct
     7681 cggcgtcctg cccgcaacgc tggtggcccc gatgacaatc tgggcgccga agaccctcgc
     7741 cgtgttcata ctcgacgtca cgtacaccac gatctgctgg ctgctggctt ggcgactgct
     7801 caagcgccgc gatcgaattt cggatgatct gacctaccgg gtctacgccg ccttgtcctg
     7861 cgctctcgcc gccagcccac tcctactctg actgcgacgg gttggcgccg gcacagccgc
     7921 tgcaattctt atcgcgaacg ctttggtgct cggtggcgca ccgaaattga ggtcacccga
     7981 accgcatggt taccggcgaa cgttccacaa cggaaggccg tgcatcgcgg tgatcaccgc
     8041 gcgctccagc gcgagtgcgt tggcgcggtc tcccgtactg gtccaccgga cgtacaagtc
     8101 caggtgatca atagccgcgc gtgcccactg tttcgcgctg tgcacttcgc cggactccaa
     8161 gagagccagc cgttcgcgaa cccattttgg gtcggccagc gcgcggttga acgcggcttc
     8221 gccgagtccg cttacggctg ccttgcccga ggagtaaatg tagagccgcc cgcgaatgcc
     8281 cttgcctttg cgtttgccgg ccattccgac atacacgatc gggccgtctg atccggtgcg
     8341 tgccatatag acacccggcg cacgtgtcgc ctctaaacac gcctggtcga atgggcacca
     8401 cgccgaccat tcggccatcg cgtcgatgtc agcggtcatc ggggaattct agcgtcgtca
     8461 cgacttgatc gactgagcgc agcgagcgcg acgccaatat tgatgtcggg gaacggctcg
     8521 ctttcgatct cctcgcgcca cgcggcgagg acggtgacca gctcacacca cgtgaccacg
     8581 gcgcatccct ctacctcgat tggacccggg cgacgcctcg atgccggtga cgtcgcccac
     8641 gtcgagccca gccagttccc cggcgcgcgg acccgtgtac gccacaaatt ccaccatcag
     8701 cccgtaaacc gggtaggtct ccgcgatcgt gtgtgccccg agagaggggc atcgcaccgc
     8761 tgattgagcg gtcgaaagat cagcgtcttg tgttcgtggg taacgggctt gtcgatggcg
     8821 ccgagcgagt gcaggtcgat gactacctcg ttgaacgttc gtacacctgt gtggtgtgcc
     8881 ccgcgcagcc ggcacgttgg agtacttagc ctccaccttg cgtcgggccg aaccatccat
     8941 cgggcaattt ggcgacagtc gatttcgcga cgctgcaggt acgacttgat cgccgacccc
     9001 ctgggcgctg tcatgtccag gtcggaggag gccgaatctc aaggaccgag gcggacgacg
     9061 ctcagaatcc gcggatcggg tcccggcgca gacgttcgca caattgcgtc ggcagcacac
     9121 ggtgctccca gaggatgcgg gcaatatcag catggaggac ctcgcccgac gccccggtgg
     9181 ccgtgccgcg cagctgtttc catgcccgca ccgtgtcgtg cgcgatgtcc agcatgagct
     9241 tcggagaacc cgccgatctc cggcatcggc aacgcaccgc aacccgtcca acgcgactac
     9301 aacctcgccg tcacccacta gccacgccgt cggtgaaccc gcgtcccgca caccacacca
     9361 ggtgcgcggg acgcacccgc tggagataca aggccagcac gatgaccacc tggtgctgca
     9421 cgggcggtca gagtggggcg atcatggcga ccatgacggg atcgctgccg gcagtgatca
     9481 cggacgtaga tgccaggtgg cgatcagttg ccgagcctcg gccagagagc tccgcacgac
     9541 cgactgatcg aggttgaagg ccgtcgcgac atcctcaagc gtcaccgagc ccgattcggc
     9601 gagacgatcc agcacctcca ggagggcccg ctgccgaagg tcgcgcggct gcgccggtgg
     9661 cggttcgggt gtgggcatcg gccgtgcggc ccgcatctcc tccggcgtcc agcgccgtgt
     9721 cgccggcgtc ccggggtgcg cgcgaaagcc ccctgcgacg ggctcgtcgt cgttcatatc
     9781 aacatagagt agtcgctgac taggaaagtc aagggctgaa tgggcctcag ccggggggtg
     9841 ggtggcctcc acgtcacgtc gcgaagtctt tacctggcga gctgttcgat cacccgatcg
     9901 gcggtaggtg cgggtcccga ccgccattac tcttttgatc tgcactgggg tttcgggggc
     9961 ccattcgtgc atttctgttg aacgtcatgg ggagtctatg tggatacgag atcgagatta
    10021 gcgagatgtg ttgcacgggc gttggtggcg gcgacgatac tcgcggcggc cttgtcagca
    10081 acggaattag caaacgtcga tataaacgat cagaagcgtt cccaatccgg atggagtatc
    10141 accgaagccg cgactacggt cagagctgac ggcgcagaaa agagtaaagc acttcgcaaa
    10201 gtgtggacgc cggaccgcat gagaaaggcg agaccgctgc ccaccccggt gatcacggcg
    10261 cctgaccttg ctcgcgagcc ggaaagacta cgaactggag gcggcgagca tcccgccgat
    10321 accgccgagt gcgggcgttc taccggtagg tcccgccgcg gtgtacgact ccgacgctcc
    10381 aacggtggga aagctcttct ttctggatgc gacaaccaac atcgactacc gctgctccgc
    10441 atccgtggtg gtcgcaccga acaagagaac ggtactgacg gcggcacatt gcctgttcga
    10501 cccatctcga caggtcgggt acgtcgatca cttcttcgcc ccagcctacg tcgacggtaa
    10561 tgcaccgtac ggcgtctggg acatggccga gtacattgtt cacgacaaat gggtcaacga
    10621 gggaaagctt cacttcgact acggtttcat gcggatgacc cgagacgacg gcgtacacat
    10681 tcaagacgtg gtcggagcgc tcggtttcgc atggaatcaa acgaacgggt tcatcgatgc
    10741 gatgggctac ccagcgaatc caccatacga cggagaaagg cagaaacgcg acttcactaa
    10801 cagcaccatt gtcgacttcg cgaacgacgg cggtggagtg ctggagggtt ggttcgacga
    10861 gatcatcagc gactttggag gcggatcgag tggcggacca ttcgtccgag actacaatcc
    10921 acagaatcga ctgggcttcg cccggggcgt caactcgttc aggatccccg accggccata
    10981 cgtgtattcg gcgtacttcg acggtgatgc gaaagtcggt aaggacttcg cgggcgagag
    11041 cggcaccgga acgcaaactc tgcgagcatc ccgatgggct ccagaaggtg tcggaccgct
    11101 cacaacgaga gccacgacgc ctgggacgac atggtgtccg taaccttgga tctgggtagc
    11161 gttgcacttg tcgccgcacc cttggaaccg gtgccacagc cggccctgga cgatcccacg
    11221 atcagcctca tcgttctcgg gttcctggtc gtgctgaacg cggcggtcaa acctggccga
    11281 accgctcgtg ccaccgctgg agttccttgc ccctgcggcc gagccggtgg cgatcgcggt
    11341 ggtgacgctg ctgctggcgt tcatcactct cgtattcggt gagctggcgc ccaaacggct
    11401 ggccatgcag cacgcgctgc gctgggcgct ggtcgtggcc tgaccgctgg actggctggc
    11461 gacggtctcc cggcccgccg tgtggctact cagcaaagcc accgacctga ccgtccgcgc
    11521 gttcggtggc aatccttacg ccgcgaagga agagttgtct gcgttgcctt ggccgcttgg
    11581 acctacggcg gcgactcatg gttgtgatcc tagtgactag acggtcactc tgcggccgct
    11641 tcgcctcaga tgaggaagag agggctgttg cgggcggagc gacgcgcgct cttcgcctgt
    11701 acccgaactc cgtccggcct gagtttgaga ttgactcctc tgggttcagg tgtcggctgc
    11761 ggtgagcagg tcggtgaagg tgtcgatgag gggcgcgttg gggtgagtgt tgaggcggtc
    11821 gaattggtcg gcgtcgctgc tgtggaacca ccagtggccg ctgtggtcga tcgtgaaggc
    11881 gaaggcggcg taggtcaggc cgaggtggtt catgtagcgg cgcagtgctc tttccaccga
    11941 tgggggcgtg acgatccact cgtggctcgc gagggtgaag gtgtggtcgc cgatcgcgat
    12001 gatgtgcgct tcgtgggccg tctcgacggg gtcttggaat tcggtgaggg ttgaggacac
    12061 ctggtcgagg tcatgtgtcc cgttggtgaa ccagcgagcc gcttcggggg agttggtgac
    12121 gagggtggcg gggacctgga ggccggagcc gaccgcggtc gcgagttgca acggtctgga
    12181 cgcggcgtcg gcggcgcgaa tggggtggtt gacccagagg acgtgatcca gtgcggcgag
    12241 cactccgttg aacgagagtt cggctgatac ggggagaatg gtgcgttctc ggcaccagat
    12301 ggaccggatg tcttgcagca caacggattg ccccgccgtg cacagccagc cggaccatgc
    12361 cgcgtcactc agttcagcgt cgagcacgag ctgatcgggg aaccagttcg ggtcggccag
    12421 gaataccggg acgtcgcgcc ggcggagttc atgaaccaca gcgtcgatcg tggcgtcggc
    12481 gcgttcggcg aagatgacga cggtcatcgc cgcggcaccc gattcgacgc aagccggcac
    12541 agagccgcac gaccggtggc ggtcgtttcc aggcgctcca agggctcgtc gagtgcgcac
    12601 ttcgtgatca tgagcaggcc gtcgccgatc agggtgtcgg cggcgatcgc gaggtgcgcg
    12661 ggcagtcgtc gtcgggtgtc ggcgatcaga tcgccggtgc gcaccagatc accttgggcc
    12721 gcgcgtttca gcgtcgagca acggctggtc gtcagggcgg cgacatcgcg caggtcgacg
    12781 tcgggcggat tcgcgtagtc ctcgaggcgc cggcgcatcg ggttctcctg gttcggattg
    12841 aggccgggag ccgcacggct ggggcgggag gcgggtggca ccgtgcggct cccgggcgga
    12901 cgcgggtatg cggtggacaa gctctggaac cccaccgcgc gctccccgcg cccgcttcgg
    12961 gaatcacgcg gcactcggga gcgcatccga gcccggcggt gtgcgccggt cgccgcgtga
    13021 cggtggacgc ccagcgggca gcgccgcgtc gggggaacga cgctgctcgc cgggcagaca
    13081 aggggcggct ggctcgtcgg cttcgcggca ccgacggacg cgctgtcgct cgatgacgag
    13141 cgacccgacg agcagtgccg cgggcccgcc gaccaccaac acagccatca ggccgaggga
    13201 ttggaaccag gtcatggcct gcgtccttcc gtgtggcccg atggtctaga gtggaacttc
    13261 caggttctac tgagaacctt actttggaac ttctactttg caactccacg gacgggtgac
    13321 attcgttgcc gcgctctgtg acgggcgacc aagatgggcg tccccacccc ggcaggagga
    13381 acgtcgtgga ctcaccgacg ctgcagcgtc gccggctcgc caaggcactc aagcgcgctc
    13441 gcgaggcggc gggcatgaca caggagcaag cgggcaaggc catcgacggc gcgaagagca
    13501 agatcagccg ggtcgaggcg gcgcagagcg ggtttcgggt gaccgacctg aacgtgctca
    13561 tcgagctgta cggcgtggac gaggtgactg cagcgcgtat gcgggagctt gcccgcgccg
    13621 gtcgccgacg cggtcggtgg agcgcctatc gcaatgtcac gccggactgg ttcacggact
    13681 accttgatct tgaggatgac gcctcaacca tccgctggta caagcccgag gtcgtccctg
    13741 gagttctgca gaccgaggcg tacatccgcg cggtgttcac aacggcggcg ccgcggcggg
    13801 ctgacgacga ggtcgagcgt ctcgttcggg taaggcttga acgccaggcg gtgctcgacc
    13861 gcaggagaac ccaatcgcac ttcattctga gtgagtccgt gctgcggcgt gtcgtgggca
    13921 atcccaccct gatggccaac caggcgctgc acatcgctga gatcgcggaa tacagcaatg
    13981 tcgacgtgca gatcttgccg ttcaacgccc agacctactg cccggcgagc gtcgtgttca
    14041 ccatgctgcg gtttgacgac aacccaagta ccgacgtggt gtacctggag gactacaccg
    14101 acgccgacta cctcgacgac gaggcgccgg tccgcgcata cactgacctg tggaaccgct
    14161 tgtcggcggc cgcgcttggt caggtcgagt cccaggaact gctcagggag atcgccggcg
    14221 agcacaagca tcccaagccg aagtgagccg acagcgatga acaccccgga tctctcccgc
    14281 ttcgcctggc ggaagagcag ttacagcagc gacaacggcg gcgcgtgtgt cgagatcggc
    14341 ctgccgcccg aagcgtggcg caagagcagc tacagcgagg acaacggcgg tgactgcgtc
    14401 gaggtggccg cactcgccga cgcggccgcg atccgcgact cgaagaatcc ggacggcggc
    14461 gcgctcatgt tgagcggcgc cgtctggaac gcattccgga ccgcgatccg cgcctgacac
    14521 gatcaacatg aacgagggcg gctcatcgag ccgccctcgt ttgtctgcgg ccgaatggct
    14581 tcgcgttcgt aaggcgccag gggtacgcgg acgtgaattg accgaactgg ccgctcggct
    14641 ctatccggaa tcgcagcgcg ctcctggtgg ccacgtgttg gccggcccgg gttggctgtt
    14701 ggacgaaccg gtcgaactcg actcggttcg cttgatctgg tccgacatcg aggaccctgt
    14761 tcccagtctc gggccagttg atcacgtgct gcccttgacc gaccggggcg agcggtatgc
    14821 cgactacagc agagctgtgc gcgacctggt gcgtcctcgg ctgttggaga accggttgag
    14881 ctaccggctc ctggatgtcc agagccacaa cggtttggcg ctgaccttcg ggacgacgac
    14941 gttcttcgag gtgttcaacg tcaagcagat gatcgcgcac gagttcaagg ccgagtggct
    15001 gtcgtcagac ggctcggtac cgtcctggga ttccctgcca ctccggtccg ccctcggcga
    15061 tccgttcgac cctcggcgac tgttgatgtc ccctggtgtc agcacgctga ccatccggcg
    15121 ggacaaggcc ggcgagcacc ggttcgtgct gcacgaacgg gacagtgcga aagtcgctga
    15181 cgggggcggc ctgtgccacg tgatgccagc gggcgaattc cagccgtcct ccgtcgcgcc
    15241 ggccgacgtg gccaacgatt tctccctgtg gcggaacatc atgcgagagt tctcagagga
    15301 attcctcgga aactctgagc atgacgaacc ttttcgttcg ttcgagcgtg cacgcgcgga
    15361 gggccggttc cgactgtggc actacggcct ggcgctcgaa cctctggaac tcggcgcggt
    15421 ccaactgacc gtggctgtca tcgacgacga cgtattcgac cggctgttcg ctcacatggt
    15481 gacaaccaat gacgaaggcc gggtggtcgg cgcgggcggc aggaccgaca tgcctttcac
    15541 cgaggaggcg atcagtcgcc ttgatccaag gctgtccgcg agtgcgttga cccttcttcg
    15601 gctggcttgg cgcgaccgga aacgattgct gccgccggcc gggtgaatca cttgtaatga
    15661 caattgcgcg tcgagcgatg accggccgta tgcggaccgt gctcgcggag gtggcggtgg
    15721 atcggtgggc ggctccgacg acgcatcagc tgcggatctt cttggtgctc gccgacgagc
    15781 tgcatttcgg ccgcgccgcc gccctcatgt tcatgaccca accagccctc agccgtcagt
    15841 tcgacgcgct ggagcgacgc cttggcgtcc aactcatcgc gcgcaccaac cgctccgccg
    15901 aactcacccc ggccggacaa gccatcttgc cggaggcccg tgccgtggtc gacgcgatgc
    15961 gcggtttgcg gcgcgtgacg cggggacatc tcagggcggt cgccggacac ctggtcatcg
    16021 gtaccgccga ggcctcaatg ccctacaccc aggccattct ggacgaactc cgacgcggcc
    16081 atcccgacct caccttcgag gtgcggccgc tggacctggt cgagcagtac gaaagcctgc
    16141 tcgccgatga ggtcgacgcg gtcttctgcc ggccgcccgt gcccgaggga atcgcgacga
    16201 ttcaactggc caccgagcct cgggtggtgt gtctgtccgc cgacgatccg ctcgccgagt
    16261 tgcccgagat ccggctggcg cggttgcgcg accaccctgt cgtctcctac ccgtccgaat
    16321 gcccgcaggt ctggcgcgac ttctggaccg tggccgtccg tcccgacgac accgccgtcg
    16381 gcagtgggcc tgtggttcgc gacgtcgaga ccctgctgac cacggtcgca ctcggcgaag
    16441 ccatcgcatt ccttcccgcg gtggcacgcc gattccttcc ccgtcccggc atcgcttttc
    16501 tcgacgtgat cgacctctcg ccgtgcctgt ccgcactggc ctggcacgcg gcgaacggtg
    16561 accgccccac catcacggcg cttcgcagag ctgcggagac cgcgcgtaac cgatagaccg
    16621 ccgaacgcgc ggcagaagcg gcctgcccgc gcgacccgag ggccgtgcgg gcaggcgtgc
    16681 gcaagcggac tggttatccg tgcctgatcc ggaaggattc gatgcggtcg ttcatcttcg
    16741 atccgaccca cccttggagc aggcagttgc aggccttgta cgccgaccac gtctggttgt
    16801 cgccctgtgc gagcgccagg tcgtatccgg taacgacgtt acagccgttg agcgaattga
    16861 atccagatac gttgttggcc caatcatcat agatattgat ccggtacccg accgcgtcgc
    16921 atccgccata gttgccatgg attctggtca gcttgggagg attgttattg gcattccaga
    16981 accactccat gagcaatgtc tcgcccgcga tgcctgcttg ccgcgtcgcg accgacatgt
    17041 cgtcggaaca tgttcgcgac aagattggcg aagtctgatc ggccggagcc ttgccgacga
    17101 ccacaacgca gtaggctccg ctacccgtgg agggtttcat cgctgacgcg gcggtcggcg
    17161 ccacagtcat ggcgaacatc acacaaaata cagcgaacag cgtcttgacg gtgttccttg
    17221 gcgtcaactt gaactccagg tcgaatgata ataatgcctc aacgggtgac ggagctgatt
    17281 gttgccacac cgaaccgtca atgcaatgaa cgatatacag tcgtatatgg tccggcgatg
    17341 ggcgagactc gggccgaacc gaaccacgcg gtgtgcctcg gtaagaacgc gacgcggcgg
    17401 cttcctgaca tcgcctgagg aaagttcagg catacggttc tggatatggg tgatcttcag
    17461 ttcgctcgct ggtttgccgc aggggagaaa cctactgcgg ccggttgttc tcactgcccc
    17521 ggtcaccagc gtgccgcacc agtgtgatcg acctgaattt tcgcaatgac aatcccaccg
    17581 ccgtggcgat ccagaccatt tggacgcccg ccacgatcac ggtgaagctg tgggggacga
    17641 agcgctacac ggtcgaattc gtcaacggcg gccgctacgg ctccacgggt gcgccgacaa
    17701 cggtcaaatc tccgggcgat tcgtgtcgca ccagcaaggg gcagtccgga ttcagcacct
    17761 cggataccca gatcgtcggt gatctggccg gaaaggaaat ccgccgaacg cctcggacag
    17821 tggtgtacaa ctcggtgccg gcgattcgct gcgaagtcaa gcccgcacct ccgagcgcac
    17881 cgccgcccgc c
//
