LOCUS       NZ_SGWQ01000001        20999 bp    DNA     linear   CON 10-APR-2024
DEFINITION  Herbihabitans rhizosphaerae strain DSM 101727 Ga0310478_101, whole
            genome shotgun sequence.
ACCESSION   NZ_SGWQ01000001
VERSION     NZ_SGWQ01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Herbihabitans rhizosphaerae
  ORGANISM  Herbihabitans rhizosphaerae
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Herbihabitans.
REFERENCE   1  (bases 1 to 1096878)
  AUTHORS   Goeker,M.
  TITLE     Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing
            the most valuable type-strain genomes for metagenomic binning,
            comparative biology and taxonomic classification
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1096878)
  AUTHORS   Goeker,M., Huntemann,M., Clum,A., Pillay,M., Palaniappan,K.,
            Varghese,N., Mikhailova,N., Stamatis,D., Reddy,T., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-FEB-2019) Prokaryotic Super Group, DOE Joint Genome
            Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.12.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 226.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004216555.1-RS_2024_04_10
            Annotation Date                   :: 04/10/2024 19:27:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,690
            CDSs (total)                      :: 6,628
            Genes (coding)                    :: 6,561
            CDSs (with protein)               :: 6,561
            Genes (RNA)                       :: 62
            rRNAs                             :: 3, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2 (5S)
            tRNAs                             :: 54
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 13 of 67
            Pseudo Genes (incomplete)         :: 59 of 67
            Pseudo Genes (internal stop)      :: 5 of 67
            Pseudo Genes (multiple problems)  :: 9 of 67
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:31:17
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 287951
            Orig. end                         :: 308950
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            SGWQ01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20999
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="furan"
                     /region_number="2"
                     /rules="(mmyO or AvrD)"
                     /tool="antismash"
     cand_cluster    1..20999
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(mmyO or AvrD)"
                     /kind="single"
                     /product="furan"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20999
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:10999](-)"
                     /cutoff="20000"
                     /detection_rule="(mmyO or AvrD)"
                     /neighbourhood="10000"
                     /product="furan"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10999)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(mmyO or AvrD)"
                     /neighbourhood="10000"
                     /product="furan"
                     /protocluster_number="1"
     gene            complement(560..1510)
                     /locus_tag="EV193_RS01530"
                     /old_locus_tag="EV193_101309"
     CDS             complement(560..1510)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020673480.1"
                     /locus_tag="EV193_RS01530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_101309"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_130342118.1"
                     /transl_table=11
                     /translation="MVDSIVVAEGLHKRFGTTEALRSLDLRVTEGTVCGVLGPNGAGKT
                     TAVRVLCTLLVPDQGSASIAGRDVVRDADGVRKLIGLAGQHAAVDEKLTGRENLVMFGR
                     LYHLGERRAQARADELLERFDLTDAAGRLVRGYSGGMRRRLDLIASLITAPPVLFLDEP
                     TTGLDPRSRNEIWSSVRELVAGGTTVVLTTQYLDEADRLADDIAVVDHGRVIASDSPER
                     LKAVIGSRLDVVVSTVDDTPAAAAALARLTGNEPTVDGTTVSAAVHERAVSLLTAVREM
                     DAAGVAAVDVALREPSLDEVFLALTGKPAEEEVAA"
     gene            1584..2306
                     /locus_tag="EV193_RS01535"
                     /old_locus_tag="EV193_101310"
     CDS             1584..2306
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1239: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009153818.1"
                     /locus_tag="EV193_RS01535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_101310"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_242613082.1"
                     /transl_table=11
                     /translation="MPDNDVIIWARPERPARGKAPAYSRDQIAAAAVRIADADGLEAVT
                     MRRVAAEIGAGAMSLYRYVRNKDELHMLMADVVLPDTLGEPPADWREALREYARGVRRI
                     VHAHPWFPVVSAEVQVPGPNMMRGLEWLMSTVDGLGLDIDGMMEVAFTVQILAIGFAQN
                     EIAEARALARSGLTREQWQAQQGPYVEAVINSGEFPYFTRIVHDARIPHEVEGEVFDRA
                     LDRVLNGIAATLPRGTRR"
     gene            complement(2398..3684)
                     /locus_tag="EV193_RS01540"
                     /old_locus_tag="EV193_101311"
     CDS             complement(2398..3684)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005440895.1"
                     /locus_tag="EV193_RS01540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_101311"
                     /product="PhoH family protein"
                     /protein_id="WP_130342842.1"
                     /transl_table=11
                     /translation="MLDTSVLLSDPWAVTRFAEHSVVLPLVVISELEGKRHHPELGWFA
                     RETLRMLDDLRLRHGRLDKPVPIGDAGGTLHVELNHSDPSVLPPGFRTDSNDARILACA
                     LNLGAEKHDVTLVTKDIPLRVKAGAVGLDADEYRAQEVTPSGWTGMADVQVSQDAVDAL
                     FADGTVDLIEHDVEDVGELPCNTGLRLMAGTSSALGRVTADKQVRLVRGDREAFGLHGR
                     SAEQRIALDLLLDNEVGIVSLGGRAGTGKSALALCAGLEAVMERRLHRKVVVFRPVYAV
                     GGQDLGYLPGSENEKMQPWAQAVFDTLGGLVSQSVIDEVHDRGMLEVLPLTHIRGRSLH
                     ESFVIVDEAQSLERNVLLTVLSRLGTGSRVVLTHDVAQRDNLRVGRHDGVAAVIEKLKG
                     HPLFAHVTLTRSERSPIAALVTEMLEDHS"
     misc_feature    3756..3768
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.11"
                     /tool="antismash"
     gene            4265..4504
                     /locus_tag="EV193_RS01545"
                     /old_locus_tag="EV193_101312"
     CDS             4265..4504
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EV193_RS01545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EV193_101312"
                     /product="hypothetical protein"
                     /protein_id="WP_207222451.1"
                     /transl_table=11
                     /translation="MLKKAAVVAAIAAGTIAVGSPALAAGKTDHPKPPHQIGLINVGGD
                     VLNNLCVAPWYWNGPITLNLGTVTSYTACNGNEG"
     gene            complement(4583..5362)
                     /locus_tag="EV193_RS01550"
                     /old_locus_tag="EV193_101313"
     CDS             complement(4583..5362)
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012783339.1"
                     /locus_tag="EV193_RS01550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_101313"
                     /product="isoprenyl transferase"
                     /protein_id="WP_130342120.1"
                     /transl_table=11
                     /translation="MSLRVRVRELVYRFYERQLIGQLADLDRPRHVGVVLDGNRRWARE
                     AGFTDVNDGHRVGAQRIADLLGWCQEAKVQVVTLWLLSTDNVNRPESELGPLLEIIGGV
                     VDELAEPENPWRLRIIGALDVLPTETAARLSAAALRTDGRTGMEVNVAVGYGGRREIAD
                     AVRKILQQQAEAGTSIEELAEAFDVDHIAEHLYTSGQPDPDLVIRTSGEQRLSGFLLWQ
                     SAHSEFWFTEAYWPDFRRTDFLRALRDYAVRHRRFGS"
     gene            5431..7368
                     /locus_tag="EV193_RS01555"
                     /old_locus_tag="EV193_101314"
     CDS             5431..7368
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF020683.4"
                     /locus_tag="EV193_RS01555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_101314"
                     /product="galactose oxidase-like domain-containing protein"
                     /protein_id="WP_130342121.1"
                     /transl_table=11
                     /translation="MQRRQPAATRRLALVLGIGVIAMPYLVNSWQEAGTGAASPADAHH
                     HDVVPAAAMEPFARPLPRAGWVVSEDAGRSITVDMRRVHPVSGLRYTPRGNAIERYEIR
                     LSPDGRTWSAPVATGTLADDTETKTLQFATAHARMVRLTALSTARPAEPVGAAQIDVLG
                     SPPASTDKAGKAVRAPGAWDPVIGFPIVPAAAAVLPNGKLLTWSAVGSDYSALDSKATQ
                     TAVLDPITRVVGRKQIDDTGHEMFCPGVSRDPDGRVVVTGGSDANKTSVYDPGSDRWSV
                     GPAMNVPRGYHGQVTLSNGDTFLVGGSWHGGLGGKSGEVLSRAENTWRMLPGVSPDPFL
                     TRDPGGVYRQDNHAWLFAASRGRVFHAGPSTQLNWVSTAGEGSVTLAGIRGGIDAVNGN
                     AVMYDIDKILTVGGATAYENADATTDAYVMDIGGPAPVVHRTGGLNVPRTFINSVVLPD
                     GKVITFGGMRYAELFADRTAVLEPEMWDPATGAFTTLAPAAVPRAYHSVAVLLPDGRVF
                     SGGGGLCGQCATNHPDGQIFTPPNLLDAEGRPKPRPVITEAPGTVAPGDEITVRADRPI
                     AGLALVRAGGATHTVDNDQRRVPLAVAGVSDNQRVAVPGDPGIVPPGYYMLFALDEQGT
                     PSVSAPVFVR"
     gene            7384..7821
                     /locus_tag="EV193_RS01560"
                     /old_locus_tag="EV193_101315"
     CDS             7384..7821
                     /GO_function="GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018683219.1"
                     /locus_tag="EV193_RS01560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_101315"
                     /product="CoA-binding protein"
                     /protein_id="WP_130342122.1"
                     /transl_table=11
                     /translation="MHRTEVDPRWQDIEVIERLARESRTIAVVGLSDDPTRPSHRVASY
                     LRGAGMTILPVNPKIETWQGLRAYPSLDALEKPVDIVDVFRRPEHAVALAEQAVAIGAG
                     ALWLQMGVINDEAARIASDGGLDVVMDRCLLVEHREVVGWS"
     gene            7929..8555
                     /locus_tag="EV193_RS01565"
                     /old_locus_tag="EV193_101316"
     CDS             7929..8555
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005451288.1"
                     /locus_tag="EV193_RS01565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_101316"
                     /product="hemolysin III family protein"
                     /protein_id="WP_130342844.1"
                     /transl_table=11
                     /translation="MRGKIHFWSFFVSIATGATLISLAAATVSGKAALATSVYGATVLG
                     LFGVSALYHRRWWASLTVRAWMKRLDHSMIFLFIAGTYTPFCLLAMPESTGYVVLGVVW
                     GGAVAGVALKLLWPHAPRWIGTPIYIALGWVAVFVLPDLAHHAGVAALVLLLVGGGFYT
                     LGAVFYATRWPDPWPRVFGHHEFFHAATVLAAICHYIAIWLAMYP"
     gene            8603..9304
                     /locus_tag="EV193_RS01570"
                     /old_locus_tag="EV193_101317"
     CDS             8603..9304
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1195: IclR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016333469.1"
                     /locus_tag="EV193_RS01570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_101317"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_130342123.1"
                     /transl_table=11
                     /translation="MTRGVLDGAFALLEALDGRELRPSELAKYCGLPKTTTHRMLDQLV
                     ALGAVERAGEHYRIGHTLFRLGATWTPAGRLSAAARAAARGLAATRSDCTVGLVAFSDS
                     RTIVVNTLHGERFPGGFPSPGTIVPAGMEPDLVRAAFAPDTDPPDGYTTTEWRRLVWAV
                     RARDGVVTTGQYFGDLGLSVAGAPVRDRSGTAIGAIGIVVHGHTPVHKLEPLVLRAARL
                     TSGTLARSVSR"
     gene            complement(9294..10001)
                     /locus_tag="EV193_RS01575"
                     /old_locus_tag="EV193_101318"
     CDS             complement(9294..10001)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024911.4"
                     /locus_tag="EV193_RS01575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_101318"
                     /product="AAA family ATPase"
                     /protein_id="WP_130342124.1"
                     /transl_table=11
                     /translation="MKLAVSGTYSSGKTRTVMALSHYTGIPRTLAKAIREILPSAVPGK
                     KLAEVTPAEFLQLMLRRHTGRAVQEGLLGDHFLSDGSSLQEWLYGAARVRHGMNPNATA
                     HRDQVPVAEDEMAFFAKVVDQFGFAFKQHVKGTYDAFVHLRHELPITDDGHRPMNERFR
                     EIIDDMLLVTLAELDIPVHVVSGGFAERITAIVERFDLPTVMPLPDAIALADDDYAALD
                     LRLETERAVVATG"
     gene            complement(10001..10999)
                     /locus_tag="EV193_RS01580"
                     /old_locus_tag="EV193_101319"
     CDS             complement(10001..10999)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) furan:
                     AvrD"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017469.4"
                     /locus_tag="EV193_RS01580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_101319"
                     /product="AvrD family protein"
                     /protein_id="WP_130342125.1"
                     /sec_met_domain="AvrD (E-value: 7.4e-106, bitscore: 350.2,
                     seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTVEATRLRLNSVDDYLGPAETRFFGNGYRRAEYDVGDIAVDGA
                     GVRSTVGVRYPVDWSRKAAGDLRPHLSTVDMLVLGVQLCEVHLAAAGLDADARRRAWLR
                     KITLRAGTRPQEELDGLHGAATLRERHTARDEAVSVYDCAIGTMRARCEIVHPRVDEGA
                     AGTFRSIEEAVGEAGGRFYGDGFRRRSHRISDVVVDLDGRRSSARLRIAQDGRVSDGID
                     GAYQPSVSLIDCFVGNLQLAQVMMYEMDAVKRSDSNTLWMLKTVLESSGPRRPWSGEIA
                     TEAAITRKQLLPLRGGVWRSVDIEAKCGGVELRSSFAHELPDYAYDVTGDR"
     gene            complement(10996..11265)
                     /locus_tag="EV193_RS01585"
                     /old_locus_tag="EV193_101320"
     CDS             complement(10996..11265)
                     /NRPS_PKS="Domain: PP-binding (14-63). E-value: 2.4e-08.
                     Score: 26.1. Matches aSDomain:
                     nrpspksdomains_EV193_RS01585_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012759.4"
                     /locus_tag="EV193_RS01585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_101320"
                     /product="phosphopantetheine-binding protein"
                     /protein_id="WP_130342126.1"
                     /sec_met_domain="PP-binding (E-value: 1.4e-07, bitscore:
                     28.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTQTDVRSTVLSEINTILLDVLDESTEFSGGDELYELGINSLAL
                     ARLLIQLEAATGVDPFASEEVAVSDIRSVDDLVAAYESARGGSA"
     aSDomain        complement(11077..11223)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EV193_RS01585_PP-binding.1"
                     /evalue="2.40E-08"
                     /label="EV193_RS01585_PP-binding.1"
                     /locus_tag="EV193_RS01585"
                     /protein_end="63"
                     /protein_start="14"
                     /score="26.1"
                     /tool="antismash"
                     /translation="INTILLDVLDESTEFSGGDELYELGINSLALARLLIQLEAATGVD
                     PFAS"
     gene            complement(11259..11999)
                     /locus_tag="EV193_RS01590"
                     /old_locus_tag="EV193_101321"
     CDS             complement(11259..11999)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (9-171). E-value: 1.5e-13. Score:
                     43.0. Matches aSDomain:
                     nrpspksdomains_EV193_RS01590_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024950.4"
                     /locus_tag="EV193_RS01590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_101321"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_207222452.1"
                     /sec_met_domain="adh_short (E-value: 5.5e-35, bitscore:
                     117.0, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 6.5e-31, bitscore:
                     104.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPADTPVAIVSGGSRGLGSVLVERLLKRGWRVATFSRSAGEFV
                     ERTEAAAGESFWWQAADLGQPDTLRGFVADVLGRFGRVDLLVNNAGVLHQELFVTTPPA
                     AIERLITANLVAPVTLAHACARAMCRQRGGVIVNVSSINAIRGFRGVAVYSAAKAGLDG
                     FGRSLARELGPLNIRVNSVVPGFFDTEMTAEVTEENRKRIQRRTPLGRLAGIDEMADAA
                     MFLCSEEASFITGQTIVVDGGITC"
     aSDomain        complement(11487..11972)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EV193_RS01590_PKS_KR.1"
                     /evalue="1.50E-13"
                     /label="EV193_RS01590_PKS_KR.1"
                     /locus_tag="EV193_RS01590"
                     /protein_end="171"
                     /protein_start="9"
                     /score="43.0"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="AIVSGGSRGLGSVLVERLLKRGWRVATFSRSAGEFVERTEAAAGE
                     SFWWQAADLGQPDTLRGFVADVLGRFGRVDLLVNNAGVLHQELFVTTPPAAIERLITAN
                     LVAPVTLAHACARAMCRQRGGVIVNVSSINAIRGFRGVAVYSAAKAGLDGFGRSLARE"
     CDS_motif       complement(11502..11582)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EV193_RS01590_0002"
                     /evalue="5.90E-05"
                     /label="PKSI-KR_m4"
                     /locus_tag="EV193_RS01590"
                     /protein_end="166"
                     /protein_start="139"
                     /score="15.6"
                     /tool="antismash"
                     /translation="SSINAIRGFRGVAVYSAAKAGLDGFGR"
     CDS_motif       complement(11883..11969)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EV193_RS01590_0001"
                     /evalue="4.90E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="EV193_RS01590"
                     /protein_end="39"
                     /protein_start="10"
                     /score="9.6"
                     /tool="antismash"
                     /translation="IVSGGSRGLGSVLVERLLKRGWRVATFSR"
     gene            complement(11996..13339)
                     /locus_tag="EV193_RS01595"
                     /old_locus_tag="EV193_101322"
     CDS             complement(11996..13339)
                     /NRPS_PKS="Domain: AMP-binding (14-355). E-value: 5.7e-47.
                     Score: 152.1. Matches aSDomain:
                     nrpspksdomains_EV193_RS01595_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012711.4"
                     /locus_tag="EV193_RS01595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_101322"
                     /product="fatty acid--CoA ligase family protein"
                     /protein_id="WP_207222453.1"
                     /sec_met_domain="AMP-binding (E-value: 1.5e-45, bitscore:
                     151.6, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSHAFLRGLSSFGNSDAVVFDGKTYGYAELLDGLDDWRDYLDRHD
                     VRPGQVVALDGRSSPHTCAGLLALVDRRAIAVPLNSPAAAKRAEFLDIAEVEVVITVDD
                     TGDRHCEHRHVLAGHELYRGLRDEARPGLVLFSSGTTGRSKASVLDFDKLLAKYGDQKR
                     GKRILSFLNLDHIGGINTLFHTLSQGGTVVTVAERTPDQVFATIAAHRVGVLPTTPTFL
                     NMVLISGALGRHSTESLRLITYGTEPMPELTLRKLTAALPNVRFKQTYGLSELGILPTR
                     SRSDGELWFALGDDGFRHKIVDNVLWIKSDMAMLGYLNAPAPFDDEGFFNTQDVVETDG
                     DYIRVLGRRSEIINVGGEKVYPAEVENLLLEIPNVVEATVSGHPSPVTGMVVKATVRLA
                     EHEAESSLRERIRAFSAGRLEPFKVPALIEVTTRAQHSDRFKKVRSTV"
     aSDomain        complement(12275..13297)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EV193_RS01595_AMP-binding.1"
                     /evalue="5.70E-47"
                     /label="EV193_RS01595_AMP-binding.1"
                     /locus_tag="EV193_RS01595"
                     /protein_end="355"
                     /protein_start="14"
                     /score="152.1"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="SDAVVFDGKTYGYAELLDGLDDWRDYLDRHDVRPGQVVALDGRSS
                     PHTCAGLLALVDRRAIAVPLNSPAAAKRAEFLDIAEVEVVITVDDTGDRHCEHRHVLAG
                     HELYRGLRDEARPGLVLFSSGTTGRSKASVLDFDKLLAKYGDQKRGKRILSFLNLDHIG
                     GINTLFHTLSQGGTVVTVAERTPDQVFATIAAHRVGVLPTTPTFLNMVLISGALGRHST
                     ESLRLITYGTEPMPELTLRKLTAALPNVRFKQTYGLSELGILPTRSRSDGELWFALGDD
                     GFRHKIVDNVLWIKSDMAMLGYLNAPAPFDDEGFFNTQDVVETDGDYIRVLGRRSEIIN
                     V"
     CDS_motif       complement(12893..12940)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EV193_RS01595_0001"
                     /evalue="2.40E-03"
                     /label="NRPS-A_a3"
                     /locus_tag="EV193_RS01595"
                     /protein_end="149"
                     /protein_start="133"
                     /score="11.0"
                     /tool="antismash"
                     /translation="VLFSSGTTGRSKASVL"
     misc_feature    13437..13453
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: medium, score: 26.96"
                     /tool="antismash"
     gene            complement(13669..15363)
                     /locus_tag="EV193_RS01605"
                     /old_locus_tag="EV193_101323"
     CDS             complement(13669..15363)
                     /EC_number="1.11.1.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013225606.1"
                     /locus_tag="EV193_RS01605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_101323"
                     /product="vanadium-dependent haloperoxidase"
                     /protein_id="WP_242613083.1"
                     /transl_table=11
                     /translation="MEFATAERGVIDAPILGEHANGDAPRNRPRHGVGDDGVARWWPAA
                     PARWIGPTQPAPDPAQRVRHGRAVRSQAAELGYPTYLPEHPDNGEESDYPFLAVYSKGL
                     PHNELGEVEPAAYRMLRHALRTGHPADFDRIPQGIGNARKQLGPQGGLALDLLGPDPQA
                     LVVPPAPRVDSGLVAAEMAELYWMALLRDVPFTEFEESPLAAVAAADLTRYAAYRGPRE
                     NGIVTPRTLFRGDTRGDRTGPFISQFLLQTVPYGTYRIPQLSDTVQPGVDYATEFGEWL
                     AVQRGMVAQTPRDFVNTRYIQTPRDMGHYTHFDVLYQPYLYACLVLLGMPGYPAALQDH
                     GNPYLHSPNQVGFPTFGTPHLVTMLAEVANRAIKHTEYQQFFVHRRLRPEALGGRIEVH
                     LAHDRGRYDGILHPAMLDSEVLDRVRGTFGSCLLPQGFPEGSPMSPSYQSGHSTVAGAC
                     VTVLKAWFNEAAPLPDPVVPSPDGKTLVPYQGFGSDGLTVGGELNKLASNVGAGRAMPG
                     VHYRSDNTEAFRLGEEIAIRMLREKKSTYRESCAFSLTRFDGTAITV"
     misc_feature    complement(15316..15318)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(15407..16555)
                     /locus_tag="EV193_RS01610"
                     /old_locus_tag="EV193_101324"
     CDS             complement(15407..16555)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1184: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="EV193_RS01610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_101324"
                     /product="MFS transporter"
                     /protein_id="WP_130342129.1"
                     /transl_table=11
                     /translation="MTVAVGTVVANLYYAVPLEHALAEAFHVSDRAIGLAVSLIQIGYA
                     IGLATLVPLGDLLERRGLLMPMLICNVAGMVTMAVASGYAVFVVAAAIVGVTSVAVQVL
                     VPFAAELAPPDQRGRVVSTVMSGLLVGVLISRTVSGLIADAADWRAVFAFGALITAVVA
                     LLLHRRLPVLAPRATMRYRELLGSVVTIVREEPQLRLRMLYGGLCFAAFNAFWTGSTFL
                     LGGPDYGWSTSAIGLFALVGVVGALSARFAGRLADKRKVHRGTGIFLIATALSFGLIAL
                     GEYSLAALVVGVAVMDMGCQGVHISNQSVIYALRPEARSRINTAYMTFYFVAGALGSGL
                     SSLIYPEFGWVGVSVFAFAVPAAGVIVWGARAISARRGASPV"
     gene            16705..17304
                     /locus_tag="EV193_RS01615"
                     /old_locus_tag="EV193_101325"
     CDS             16705..17304
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF037675.4"
                     /locus_tag="EV193_RS01615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_101325"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_130342130.1"
                     /transl_table=11
                     /translation="MAWDTEQTRRRLKEAATEEFAANGLNGTTVERIARRASVNKERLY
                     HYFGDKEQLYAAILNDELVRIAEAVQLPSAEDMDVGEFAGRVFDYHSSHPHLARLLHWE
                     GLSYAGKIPLQEKRTPYYTAKVDAIKAAQRAGGITDELDPADLAFMLIALAAWWFAVPQ
                     VVQMLTGQTGDDPADRAKQRAAVVIAARRLAHDPPR"
     gene            complement(17535..18131)
                     /locus_tag="EV193_RS01620"
                     /old_locus_tag="EV193_101326"
     CDS             complement(17535..18131)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1197:
                     autoinducer-binding transcriptional regulator,"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012422.4"
                     /locus_tag="EV193_RS01620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_101326"
                     /product="response regulator transcription factor"
                     /protein_id="WP_207222454.1"
                     /transl_table=11
                     /translation="MRNDLLRGGLEKMLDALGMTEVASRRDLRGGLDTARGRSVLIARL
                     AEVDGATVADLRAAVRAGMRVLLLVADGDLELVEPGWVLDGVGYLGVDDLDERALHNAL
                     CGTDGASSLPSGLARWLPAILRQRATAASAAPRLTPRERQVLALLVEGLSNKQIARRLR
                     ISEHGAKRLVANILAKLDCPNRTLAVARAVRDGVV"
     gene            complement(18363..18935)
                     /locus_tag="EV193_RS01625"
                     /old_locus_tag="EV193_101327"
     CDS             complement(18363..18935)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020641247.1"
                     /locus_tag="EV193_RS01625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_101327"
                     /product="hypothetical protein"
                     /protein_id="WP_130342132.1"
                     /transl_table=11
                     /translation="MRRGWHGHGRGRGKGGWQQADLPSADDAAAWFEGRLPDEWFTGAP
                     VVMVDREEIILVGELPELSGEFDDEAARSAAESGRISRWREQTRDERIEIARQAEHRYQ
                     RKVAWGAKLGSTEELFTTISVPVMTRLRQPERLVLDTLVDAGVARSRSEALAWAVRLVG
                     EHAESWLDELRDAMSTVDDLRSRGPEL"
     misc_feature    18940..18960
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 22.54"
                     /tool="antismash"
ORIGIN
        1 ttcgacagca tcgtgaccgg aaagaacagc ggcgtcagcc gatcggccgt ctcctcgttg
       61 cgcaccaaca gtcccagcaa cacgccgagc cagttgaacg cgtaggtgaa cagcagcagc
      121 acaccgaagc cggccagggt ggaccacagt ccattgtgga cacgccagcc gacgatcagc
      181 cccgcgatcg ccatgatcgc catgccgacc gcgcccacca cgaggtcggc tccggtgtgt
      241 ccgaacggga cggccgaccg tgccatcggc atcgaccggt agcggtccat cacgcccttg
      301 ccgttgtccg ccgcgaccct ggcgatcgtg accatcacgg cggccgtggc acccatcgcg
      361 aacaatcccg gcatcaggaa ctcgcggtag tttccgccgc ctggcacggg aatcgcgctg
      421 ccgaagatgt acccgaagat cacgatcatg atcaccggcg agatcagcac acccaccatt
      481 tcccccggcg agtgccgcag gtgcgtcagg ttgcgtcgca tcacggtcca gccgtcggcg
      541 agcgcccagc ccatcgcgtt catgccgcga cctcctcctc ggccggcttt ccggtcagtg
      601 caaggaagac ctcgtccagg ctgggttcgc gcagcgccac gtccaccgcg gcgacaccgg
      661 ccgcgtccat ctcgcgtacc gccgtcaaca acgacaccgc gcgctcgtgc accgcggcgc
      721 tcaccgtcgt tccgtcgacg gtgggctcgt tgccggtcag ccgggccagt gcggcggccg
      781 ccgccggcgt gtcgtccaca gtggacacga ccacgtccag ccgggagccg atcaccgcct
      841 tgagccgctc cggcgaatcg gaggcgatca ccctgccgtg gtcgaccacg gcgatgtcgt
      901 cggccagccg gtccgcctcg tccaggtact gcgtggtgag cacgaccgtg gtgccgccgg
      961 cgaccagctc gcgcacgctg ctccagatct cgttgcggct gcggggatcc aggccggtgg
     1021 tgggctcgtc caggaacagc accggcggcg cggtgatcag gctcgcgatc agatccagcc
     1081 gccgccgcat cccgccggag tagccgcgca ccaatcgtcc ggcggcatcg gtcaggtcga
     1141 accgttcgag caactcgtcg gcccgcgcct gggcgcgccg ttcgccgagg tggtacagcc
     1201 ggccgaacat gaccaggttc tcccgcccgg tcagcttctc gtcaacggcc gcgtgctggc
     1261 cggccagccc gatcagcttc cgcacgccgt ccgcgtcgcg caccacgtcc cgccccgcga
     1321 tgctggcgct gccctggtcc ggcacgagca gcgtgcagag cacccgaacg gcggtcgtct
     1381 tgccggcgcc gttcggcccg agcacgccgc acacggtccc ctcggtcacc cgcaagtcca
     1441 agctccgcaa ggcttccgtc gtgccgaagc gcttgtgcag cccctcggcg acgacgatcg
     1501 agtccaccat ttcccctcct gtgggtacgt tgtacgcaca agctacgcca gtgggtacga
     1561 cgtacgcaac taggatgtcg gccatgccgg acaacgacgt gatcatctgg gcgcggcccg
     1621 aacggcccgc gcgcggcaag gcacccgcgt acagccgcga ccagatcgcc gccgccgcgg
     1681 tgcgcatcgc cgacgccgac ggcctggagg cggtcaccat gcggcgggtc gccgccgaga
     1741 tcggcgccgg cgcgatgtcg ctgtaccgct acgtgcgcaa caaggacgag ttgcacatgc
     1801 tgatggccga cgtcgtgctg cccgacaccc tcggcgagcc gccggccgac tggcgagagg
     1861 ccctgcgcga atacgcgcgc ggcgtgcggc ggatcgtgca cgcgcacccg tggttcccgg
     1921 tggtgtccgc cgaagtccag gtccccggcc ccaacatgat gcgcgggctg gagtggctga
     1981 tgtccactgt ggacggtctg gggctggaca tcgacggcat gatggaagtc gcgttcaccg
     2041 tgcagatcct cgccatcggc ttcgcgcaga acgagatcgc cgaggcgcgg gcactggcgc
     2101 gcagcggcct gacgcgcgag cagtggcagg cccagcaggg gccctacgtc gaggccgtga
     2161 tcaacagcgg cgagttcccc tacttcacgc ggatcgtgca cgacgcgcgg atcccgcacg
     2221 aagtcgaggg cgaggtgttc gaccgcgccc tcgaccgcgt gctgaacggg atcgccgcca
     2281 cgctgccacg cggcacgagg cgctagcggc gcacccatca ccgggggttt gccgtcgttg
     2341 aaggcgctcc ggaccggggt ttggtggtct tgaagaccac caaaccccgg tgcacggtca
     2401 gctgtggtcc tccagcatct cggtgaccag ggcggcgatc ggtgagcgtt ccgagcgggt
     2461 gagcgtcacg tgcgcgaaca gcgggtgacc cttcaacttc tcgatcaccg ccgcgacgcc
     2521 gtcgtgccgg ccgacgcgca ggttgtcccg ctgcgcgacg tcgtgggtga gcaccacccg
     2581 cgagccggtg cccaaccggg acagcacggt cagcagcacg ttgcgctcca acgactgcgc
     2641 ctcgtccacg atcacgaacg actcgtgcag cgagcgtccc cggatgtggg tcagcgggag
     2701 cacttcgagc atgccgcggt cgtgcacctc gtcgatcacc gactggctga ccaggccgcc
     2761 gagcgtgtcg aacaccgcct gcgcccaggg ctgcatcttc tcgttctccg agccgggcag
     2821 gtacccgaga tcctggccgc cgaccgcgta caccggccgg aacaccacga ccttgcgatg
     2881 cagccggcgt tccatgaccg cctcgaggcc ggcgcacagt gccagcgccg acttgccggt
     2941 gccggcccgc ccaccgagtg acacgatgcc gacctcgttg tccagcagca ggtccagcgc
     3001 gatccgctgc tcggcggacc gcccgtgcag gccgaacgcc tcccggtcgc cgcgcaccag
     3061 ccgcacctgc ttgtcggcgg tcacccggcc gagtgcgctg gacgtgccgg ccatcagccg
     3121 cagaccggtg ttgcagggca gctcgccgac gtcctccacg tcgtgctcga tcaggtcgac
     3181 cgtgccgtcc gcgaacagcg cgtccacggc gtcctgggac acctgcacgt cggccatgcc
     3241 ggtccagccg gacggggtga cctcctgggc gcggtactcg tccgcgtcga ggccgaccgc
     3301 gcccgccttc acccgcagcg ggatgtcctt ggtgacgagg gtgacgtcgt gtttctcggc
     3361 gccgaggttg agcgcgcagg cgaggatccg cgcgtcgttg gagtcggtgc ggaacccggg
     3421 cgggagcacc gacggatcgg agtggttcag ctcgacgtgc agagtgccgc cggcgtcgcc
     3481 gatcggcacc ggcttgtcga gccggccgtg ccgcagccga aggtcgtcca gcatgcgcag
     3541 ggtctccctg gcgaaccagc cgagttcggg gtgatgccgt ttcccctcca gttcactgat
     3601 gacgaccagt gggagcacga cggagtgctc cgcgaagcgg gtgaccgccc acgggtcgga
     3661 gagcagcacc gacgtgtcga gcacgtaggt gcgacattgc ttggacgggg acgaggtggc
     3721 cgaagagccg gaggaacggc tggtggtgcg cctacgtgaa gcggtcacgg caactccctc
     3781 gcgaacgcgg caccacgtcc gctcctcggt gggccgggca cccaccctgg ctggtacggc
     3841 acgccaccac cggggtcacc ggtgggggca tcgcctccca cgagggccgg gtgccggccc
     3901 cctcgcaaca tccgccacga ccagggcctc ccggaacgag ccgcatcgtc cacgacccgt
     3961 ctacttcgga agctacccgg aatcggctca ccttcacagg cagccacaca ggtgatttcc
     4021 cgattcgtca ctcttcggac acacgccgcc cccaccggcc gcccgcgagc ggcgggaccc
     4081 taggggttac ctacgggtcg cgcaaaaccg caccactgaa ccgagtgatc tttcccggga
     4141 aatgtcccac gatcggctta ctaacggtgc gtatccggcc cggtacgcgt aagtttttcc
     4201 aatgagcgcg ccacgccaaa tcggccgctc ggcaattgcc tttcaacaaa ggagcgtaat
     4261 tcacatgctg aagaaggctg ccgttgtcgc cgctatcgca gcagggacca tcgctgtcgg
     4321 ctcgccggcg ctcgccgccg gcaagaccga ccacccgaag cccccgcacc agatcggtct
     4381 gatcaacgtc ggcggcgacg tgctgaacaa cctgtgcgtc gcgccgtggt actggaacgg
     4441 cccgatcacc ctgaacctgg gcactgtcac gtcctacacc gcctgcaacg gcaacgaggg
     4501 ctgagcgcag ccagactcgc tggtggcggg ggtgcacgcg aatcttcgcg atgcatcccc
     4561 gccgttggcg cgcactttgt atttaagaac cgaaacgtcg gtggcgtacc gcgtaatcgc
     4621 gaagcgcgcg caagaagtcg gtacgccgaa aatcgggcca gtacgcctcg gtgaaccaga
     4681 attccgagtg cgccgactgc catagcagga acccggacaa tcgctgttca ccggaggttc
     4741 gaatgacgag gtccggatcc ggctggccgg aggtgtagag atgttccgcg atgtggtcca
     4801 cgtcgaacgc ctcggccagt tcctcgatcg aggtccccgc ctcggcctgc tgctggagga
     4861 tcttacggac cgcgtccgcg atctcccgtc gccccccgta accaacggcg acgttgactt
     4921 ccatcccggt tcggccgtcc gtgcgcaacg ccgcggccga cagccgtgcg gcggtctccg
     4981 tgggtagcac gtccagcgcc ccgatgatgc gcagccgcca cggattctcc ggctcggcca
     5041 gctcgtccac gacaccgccg atgatctcca gcagcggccc cagctccgac tccggccggt
     5101 tgacgttgtc cgtcgacagc aaccacagcg tgacgacctg gaccttcgcc tcctggcacc
     5161 agccgagcag gtccgcgatg cgctgcgcgc ccacccgatg accgtcgttg acgtcggtga
     5221 accccgcttc ccgggcccac ctgcggttgc cgtccagcac cacgccgaca tgcctcggcc
     5281 ggtcgaggtc ggccaactgc ccgatcaact gtcgctcgta gaagcgatag accagttccc
     5341 tgacgcggac ccgaagactc acatctgcgc acggtacgcc gtcctccgta accccgtaat
     5401 cgtgcgggtc gactcagtca cgaggtagcc atgcaacgca gacagcccgc cgccacccgc
     5461 cgtctcgcac tggtcctcgg catcggcgtg atcgccatgc cctacctggt gaacagctgg
     5521 caggaggccg gcaccggtgc cgcgtcgccg gccgacgcgc accaccacga cgtcgtcccg
     5581 gcggccgcga tggaaccgtt cgcccgtccg ctgccgcgcg ccggatgggt ggtgagcgag
     5641 gacgccggcc ggtcgatcac cgtcgacatg cgccgcgtcc acccggtgtc ggggctgcgg
     5701 tacacgccgc gcgggaacgc gatcgaacgg tacgagatcc ggctgagccc cgacggcagg
     5761 acgtggagcg caccggtcgc caccggcacg ctcgcggacg acaccgagac caagaccctc
     5821 cagttcgcga cggcgcacgc caggatggtc cggctcaccg cgctgtcgac ggcccgcccc
     5881 gccgagccgg tcggcgcggc ccagatcgac gtcctcggct caccgccggc gtccaccgac
     5941 aaggccggga aagccgtcag agcaccggga gcgtgggacc ccgtcatcgg gttcccgatc
     6001 gtcccggcgg ccgccgccgt cctgcccaac ggcaagctgc tcacctggtc ggccgtcgga
     6061 tccgactact cggcgctgga cagcaaggcc acccagacgg ccgtcctgga cccgatcacg
     6121 cgcgtggtcg ggcgcaagca gatcgacgac accggccacg agatgttctg ccccggcgtg
     6181 tcccgcgacc ccgatggccg ggtggtggtg accggcggct ccgacgccaa caagaccagc
     6241 gtctacgacc cggggtccga tcgctggtcg gtcggcccgg cgatgaacgt gccacgcggc
     6301 tatcacgggc aggtcacgct gtccaacggg gacacgttcc tggtcggcgg ctcgtggcac
     6361 ggtggcctcg gcggcaagag cggcgaggtc ctctcgcgcg cggagaacac gtggcgcatg
     6421 ctccccgggg tgtcaccgga cccgttcctc acccgcgacc ccggcggcgt ctaccggcag
     6481 gacaaccacg cctggctgtt cgccgcctcg cgcggccggg tgttccacgc cgggccgagc
     6541 acacagctca actgggtcag caccgccggc gaggggtcgg tcacgctggc gggcattcgc
     6601 ggcgggatcg acgcggtcaa cggcaacgcg gtgatgtacg acatcgacaa gatcctcacc
     6661 gtcggcggcg ccaccgcgta cgagaacgcc gacgccacga cggacgcgta cgtgatggac
     6721 atcggcggtc cggctcccgt ggtgcaccgg accggcggcc tgaacgtgcc caggacgttc
     6781 atcaacagcg tcgtgctccc ggacggcaag gtgatcacgt tcggcggaat gcggtacgcg
     6841 gagctgttcg ccgaccggac ggccgtgctc gaaccggaga tgtgggaccc ggcgaccggc
     6901 gcgttcacca cgctggcgcc cgccgcggtg ccccgggcgt accacagcgt cgcggtgctg
     6961 ctgccggacg gcagggtgtt ctccggcggc ggcggcctgt gcgggcagtg cgccaccaac
     7021 cacccggacg gccagatctt caccccgccg aacctgctcg acgccgaggg ccggccgaag
     7081 ccgaggccgg tgatcaccga ggcgccgggg acggtggcgc caggcgatga gatcaccgtc
     7141 cgagccgacc ggccgatcgc cggactcgcg ctggtgcgcg cgggcggtgc gacccacacg
     7201 gtggacaacg accagcgcag ggtgccgctc gcggtggccg gagtgtcgga caaccagcgc
     7261 gtcgcggtgc ccggcgaccc cggcatcgtg ccacccgggt actacatgct gttcgcgttg
     7321 gacgagcagg gaacgccgag cgtctccgcg cccgtgttcg tgcggtaggc gcacactggg
     7381 accatgcatc gcaccgaggt cgatccgcgc tggcaggaca tcgaggtcat cgaacggctg
     7441 gcgcgcgagt cgcgcacgat cgcggtcgtc gggctgagcg acgatccgac gcggccgagc
     7501 caccgggtgg cgagctatct gcgcggcgcg ggcatgacga tcctgccggt caacccgaag
     7561 atcgagacct ggcaggggct gcgcgcgtac ccgtcactgg acgcgctcga gaagccggtg
     7621 gacatcgtgg acgtgttccg gcggcccgag cacgccgttg cgctggccga gcaggcggtc
     7681 gcgatcggtg ccggcgcgct gtggctgcag atgggcgtga tcaacgacga ggcggcgcgg
     7741 atcgcctcgg acggcgggct ggacgtggtg atggaccgct gcctgctggt cgagcaccgc
     7801 gaagtcgtcg gctggagcta gtgactcccc ctactagtgg atgacgcgag aacctacggt
     7861 gccgtagcct caaaggcgtg acagcagcga ccctcgagcg gccgcctggt ccgcacatca
     7921 agccccgcat gcgcgggaag atccacttct ggtccttctt cgtctcgatc gccaccggtg
     7981 ccacgctgat ctcgctcgcc gccgccacgg tgtcgggcaa ggcggcactg gccacctcgg
     8041 tgtacggcgc gacggtgctg ggcctgttcg gcgtgagcgc gctgtaccac cggcgatggt
     8101 gggccagcct gaccgtgcgc gcctggatga agcgcctcga ccactcgatg atcttcctgt
     8161 tcatcgccgg cacgtacacg ccgttctgcc tgctggccat gccggagtcg acggggtacg
     8221 tggtgctcgg cgtggtgtgg ggcggcgcgg tggccggcgt ggcgctgaag ttgctgtggc
     8281 cgcacgcgcc gaggtggatc ggcacgccga tctacatcgc gctcggctgg gtcgccgtgt
     8341 tcgtactgcc cgacctggcc caccacgccg gagtcgcggc gctggtgctg ctgctggtcg
     8401 gcggcgggtt ctacacgctc ggcgcggtct tctacgccac ccgctggccc gacccgtggc
     8461 cgcgcgtgtt cggccaccac gagttcttcc acgcggcgac cgtgctcgcc gcgatctgcc
     8521 actacatcgc gatctggctc gccatgtatc cctgagccgc cgtacagttg tctcccacca
     8581 gttattggtc cgggggggga tcatgacgcg cggagtgttg gacggggcgt tcgccctgct
     8641 cgaggcgttg gacgggcgcg aactgaggcc gtcggagttg gccaagtact gcgggctgcc
     8701 gaagaccacg acacaccgga tgctcgacca gctcgtcgcc ctcggggcgg tcgagcgggc
     8761 cggcgagcac taccggatcg gccacacgct gttccggctc ggcgcgacct ggaccccggc
     8821 cggccggctg agcgcggccg cgcgggctgc ggcacggggg ctggccgcca cgagatccga
     8881 ctgcaccgtc gggctggtcg ccttctccga ctcgcgcacg atcgtggtga acacgctgca
     8941 cggtgaacgg ttcccgggcg gctttccgtc ccccgggacg atcgtgccgg ccgggatgga
     9001 gccggacctg gtgcgcgccg cgttcgcgcc ggacaccgat ccgccggacg ggtacaccac
     9061 aaccgaatgg cgccgcctgg tgtgggccgt gcgggcccgc gacggcgtgg tgaccactgg
     9121 ccagtacttc ggtgacctcg gcttgtcggt ggccggcgct ccggtccgcg atcgctccgg
     9181 cacggccatc ggcgcgatcg gcatcgtcgt gcacgggcac accccggtgc acaagctgga
     9241 gccgctggtg ctccgggcgg cccggctcac cagcggcact ctcgctcgat ccgtcagccg
     9301 gtagcgacca ccgcccgctc ggtctccagg cgcaggtcga gcgccgcgta gtcgtcgtcg
     9361 gcgagcgcga tcgcgtcggg cagcggcatc acggtcggca ggtcgaaccg ctcgacgatc
     9421 gcggtgatcc gctcggcgaa gccaccgctc acgacgtgca ccgggatgtc cagctccgcg
     9481 agggtgacca gcagcatgtc gtcgatgatc tcccggaacc gctcgttcat cgggcggtgc
     9541 ccgtcgtcgg tgatcggcag ctcgtggcgg aggtgcacga acgcgtcgta ggtgcccttc
     9601 acgtgctgct tgaacgcgaa cccgaactgg tcgaccacct tcgcgaagaa ggccatctcg
     9661 tcctcggcca ccggcacctg gtcgcggtgc gcggtcgcgt tcgggttcat gccgtgccgg
     9721 acacgtgccg cgccgtacag ccattcctgc agcgacgagc cgtcggacag gaaatggtcg
     9781 ccgagcaatc cctcctgtac cgccctgccc gtgtggcgac gcagcatcaa ctgcaggaat
     9841 tcggccggcg tgacctccgc gagcttcttt cccggcacgg cgctcggtag gatctcccga
     9901 atcgccttgg ccagggtgcg cggaattccg gtgtagtgcg acagtgccat caccgttcgc
     9961 gtcttgccgg acgaataggt accggaaaca gccaacttca tcaccgatct cctgtcacgt
    10021 cgtaggcgta atccggcagt tcgtgcgcga acgacgaccg cagttcgacg ccgccgcact
    10081 tcgcctcgat atcgaccgag cgccacactc cgccgcgcaa cgggagcaac tgcttccgcg
    10141 tgatggccgc ttccgtggcg atttccccag accacggtcg ccgaggacca ctggattcca
    10201 gaacggtttt gagcatccac agcgtgttgc tgtcgctgcg cttgacggcg tccatttcgt
    10261 acatcatcac ctgcgccagt tgaagattgc cgacgaagca gtcgatcagc gaaacggacg
    10321 gctgatacgc gccgtcgata ccgtcggaca ctcgcccgtc ctgtgcgatc cgcagccgcg
    10381 ccgaggaccg ccggccgtcc aggtccacga cgacgtcgga gatccggtgc gaccgccggc
    10441 ggaacccgtc gccgtagaac cgcccgccgg cctcaccgac ggcctcctcg atcgaccgga
    10501 acgtgcccgc ggcaccctcg tccactcgcg ggtggacgat ctcgcagcgt gcccgcatcg
    10561 tgccgatcgc gcagtcgtac acggaaacgg cctcgtcgcg ggcagtgtgc cgctcgcgca
    10621 gggtggccgc gccgtgcagg ccgtcgagtt cctcctgcgg ccgggtgccc gcgcgcagcg
    10681 tgatcttcct gagccaggct cgccgccgcg cgtcggcgtc caggcccgcc gcggccaggt
    10741 gcacctcgca cagttggacg ccgagtacga gcatgtcgac cgtgcttagg tgcggccgca
    10801 ggtcgccggc cgccttgcgc gaccagtcca ccggatatcg gacaccgacc gtcgaccgaa
    10861 cccccgcgcc gtcgacggcg atgtcaccga cgtcgtattc ggcacggcgg tagccgtttc
    10921 cgaagaatcg ggtctccgcc ggcccgagat agtcgtcaac cgaattaaga cgcaatcgcg
    10981 tcgcctcgac ggtcgtcatg ccgacccccc gcgcgccgac tcgtacgccg cgacaaggtc
    11041 gtcgacggac cgtatatccg aaacggcgac ctcctcggaa gcgaacgggt cgacgccggt
    11101 ggccgcctcc agttgaatga gcaggcgggc gagcgccaac gagttgatcc ccagttcgta
    11161 caactcgtcc ccgccggaga attcggtgct ctcgtcgagc acgtccagca gaatggtgtt
    11221 gatctcggac agtacggtgg accgtacgtc ggtttgcgtc agcatgttat tcccccatcg
    11281 acaacaattg tctgccccgt gatgaacgag gcctcttcag aacacaggaa catcgcggcg
    11341 tccgccatct cgtcgatgcc ggccagcctt cccagtggcg tcctgcgctg aattctcttc
    11401 ctgttctcct cggtcacttc ggcggtcatc tcggtatcga agaaccccgg cacgaccgag
    11461 ttgacccgaa tgttgagcgg gccgagctcg cgggcgagac tgcggccgaa accgtccagc
    11521 cccgccttcg ccgccgagta gacggcgaca ccgcggaagc cgcggatcgc gttgatcgac
    11581 gacacgttca cgatcacgcc gccccgctgc cggcacatcg cgcgggcaca ggcgtgcgcc
    11641 agcgtgaccg gcgcgaccag gttcgccgtg atcagccgtt cgatcgcggc gggcggtgtg
    11701 gtcacgaaca actcctggtg cagcacaccc gcgttgttca ccagcaggtc gacccgcccg
    11761 aaccggccga gcacgtcggc cacgaacccg cgcagcgtgt ccggctgccc gaggtccgcc
    11821 gcctgccacc agaacgactc gccggcggcg gcctcggtcc gctcgacgaa ctcccccgcc
    11881 gaacgactga acgtggcgac ccgccacccc cgcttcagca gccgctcgac cagcacgctg
    11941 cccagccctc tgctcccccc gctgacgatc gccacgggag tgtcggccgg cgccgtcaca
    12001 ccgtgctccg gaccttcttg aaccggtcgg agtgctgcgc ccgggtcgtc acctcgatca
    12061 acgccgggac cttgaacggt tccagcctgc cggcgctgaa cgcgcggatc cgttcccgca
    12121 gcgacgattc cgcctcgtgc tcggccagcc ggacggtggc cttcacgacc attccggtca
    12181 ccgggctcgg atgcccggac accgtcgcct cgaccacgtt cgggatctcc agcagcaggt
    12241 tctccacctc ggccgggtac accttctcgc cgccgacgtt gatgatctcc gaccgccggc
    12301 cgagcaccct gatgtagtcg ccgtcggtct cgaccacgtc ctgggtgttg aagaatccct
    12361 cgtcgtcgaa tggcgccggc gcgttcaggt agccgagcat cgccatgtcc gacttgatcc
    12421 acagcacgtt gtccacgatc ttgtgccgga agccgtcgtc gccgagcgcg aaccacagct
    12481 cgccgtcgct cctggacctg gtgggcagga tccccaactc ggagagcccg taggtctgct
    12541 tgaaccggac attcggtagt gctgcggtca gctttcgcag cgtcagttcc ggcatcggct
    12601 ccgtgccata ggtgatgagc cgcaatgatt ccgtcgaatg gcgtccgagc gctcccgaga
    12661 tgagcaccat attgagaaat gtcggcgtcg tcgggagcac accgacccga tgcgccgcga
    12721 tcgtggcgaa tacttgatcc ggtgtccgtt cggccaccgt caccacggtc ccaccctggc
    12781 tcagggtgtg gaacagggtg ttgatcccgc cgatgtggtc gaggttgaga aacgaaagaa
    12841 tgcgcttgcc gcgcttctgg tcaccgtatt tggcgagcag cttgtcgaag tcgagaacgg
    12901 acgccttgct gcggcccgtg gtgccggagc tgaacagtac gaggccgggc cgggcctcgt
    12961 ccctgagccc gcggtacagc tcgtggccgg ccagcacgtg ccggtgttcg cagtgccgat
    13021 caccggtgtc gtccaccgtg atcaccacct cgacctcggc gatgtcgagg aactcggcgc
    13081 gtttggccgc cgcgggcgag ttgagcggca ccgcgatcgc ccgccggtcg accagcgcga
    13141 gcagcccggc acaggtgtgc ggtgacgatc gcccgtccag cgcgacgacc tgccccggcc
    13201 ggacgtcgtg ccggtcgaga taatcgcgcc aatcgtcgag cccgtccagc agttcggcgt
    13261 atccgtacgt tttcccgtcg aacacgacgg catcggaatt gccgaaacta ctcagcccgc
    13321 gcagaaacgc atgactcact gaatgcattt aactctcccc caagagtatt cccccacatg
    13381 ggcagcctcc gctgccacat ccgagaagaa cttaaagcct cgagcactgg caggcaatac
    13441 caggatgggg tacccgttca gctaccccac ctttcgaccg tgctcgaaat tcgcagctca
    13501 accgtcgagt acttccatca tcggccattc ccatgcaccc gaggccgatt gcggagacct
    13561 ccatgccctg gctgccgagc gttcgccggc gcatcagtgc tccttatctc gggcaaagcc
    13621 ctcgaccttg tggaccgacc tcagcgtggc gattcgtgga cactcccgtc agacagtgat
    13681 cgcggttccg tcgaatcggg tgaggctgaa cgcacagctc tcccggtagg tcgacttctt
    13741 ctcgcgcagc atccggatgg cgatctcctc gccgagccgg aacgcctcgg tgttgtccga
    13801 gcggtagtgc acgccgggca tcgcccggcc ggcgccgacg ttggacgcca gcttgttcag
    13861 ctcgccgccg acggtgaggc cgtccgagcc gaacccctga tacggaacga gcgttttgcc
    13921 atcggggctc ggcaccacgg gatcgggcag cggcgccgcc tcgttgaacc acgccttcag
    13981 cacggtgacg cacgcgccgg ccaccgtgga gtgcccgctc tggtacgacg ggctcatcgg
    14041 cgacccctcg gggaaaccct gcggcagcag gcaggatccg aacgtgccgc gcacgcggtc
    14101 gaggacctcg gagtccagca tcgccgggtg caggatcccg tcgtagcgcc cccggtcgtg
    14161 cgcgaggtgc acctcgatgc gcccgccgag cgcctccggc cgcagcctgc ggtgcacgaa
    14221 gaactgctgg tactcggtgt gcttgatcgc ccggttggcg acctccgcga gcatggtgac
    14281 caggtgcggg gtgccgaagg tgggaaagcc gacctggttc ggcgagtgca ggtacgggtt
    14341 gccgtgatcc tgcaacgcgg ccgggtagcc gggcatgccg agcaggacga ggcacgcgta
    14401 caggtacggc tggtagagca cgtcgaaatg tgtgtagtgc cccatgtccc tcggcgtctg
    14461 gatgtaccgc gtattcacga agtcgcgcgg cgtctgcgcc accatgccgc gctgcacggc
    14521 aagccattcg ccgaattcgg tggcgtagtc gacaccgggc tgaacggtgt cggacaattg
    14581 tggaatccgg tatgttccgt acggaacggt ctgcagcagg aattgcgaga tgaacgggcc
    14641 cgtccgatcg ccacgcgtgt cgccccggaa cagggtgcgc ggcgtgacga tgccgttctc
    14701 gcgcggccca cgataggccg cgtatctggt gaggtcggcc gccgccacgg cggccagcgg
    14761 cgactcctcg aactcggtga acggcacgtc gcgcagcagg gccatccagt acagctccgc
    14821 catctcggcc gcgaccagcc cggagtccac ccgcggcgcg ggcggcacca ccagcgcctg
    14881 tgggtccggc ccgagtaggt ccaaggccag cccgccctgc ggcccgagtt gcttgcgcgc
    14941 gttgccgatg ccctgcggga tccggtcgaa gtcggccgga tgtccggtgc gcagcgcgtg
    15001 cctcagcatc cggtacgcgg ccggctcgac ctcgcccaac tcgttgtgcg gcaagccttt
    15061 cgagtagacg gccaggaacg ggtagtcgct ctcctcgccg ttgtccgggt gctcgggcag
    15121 gtaggtcgga tagcccagtt cggcggcctg cgagcgcacc gctctgccgt gccgcacccg
    15181 ctgcgcgggg tccggcgccg gctgcgtcgg gccgatccac ctggccggtg cggcgggcca
    15241 ccaccgcgcc acaccgtcgt cgccgacacc atgtcgcggc cgattcctcg gtgcgtcgcc
    15301 gttcgcgtgc tcccctaata tcggagcgtc gatgacaccc cgttcagccg tagcgaattc
    15361 catttcatcc cccagatatg ttgaattgac gacccatgtg gaatcgtcac accggcgaag
    15421 ccccccgcct cgccgagatc gcacgcgcac cccacacgat gacgccggcg gcgggaaccg
    15481 cgaatgcgaa cacgctgaca cccacccacc cgaattcggg atagatcagc gaggaaagtc
    15541 cgctgcccag tgcgcccgcg acgaaataga acgtcatgta cgcggtgttg atccggcttc
    15601 tcgcctccgg ccgcagcgcg tagatgacgc tctggttgct gatgtgcacc ccctggcacc
    15661 ccatgtccat cacggccacc ccgacgacca gtgcggccag cgagtactcg cccagcgcga
    15721 tcagcccgaa cgagagggcc gtggcgatca ggaagatccc ggtaccccgg tgcaccttcc
    15781 tcttgtccgc cagccggccg gcgaatcggg cggacagcgc gccaactacg ccgaccagcg
    15841 cgaacaaccc gatcgcgctg gtgctccagc cgtagtccgg cccgccgagc aggaacgtcg
    15901 agccggtcca gaacgcgttg aacgcggcga aacacaagcc gccgtagagc atccgcagcc
    15961 gcagctgggg ctcctcgcgc acgatcgtga ccaccgatcc gagcagctcc cggtaccgca
    16021 tcgtggcgcg cggcgcgagc accggcagcc tccggtgcag cagcagcgcg accaccgcgg
    16081 tgatcagcgc gccgaaggcg aacacggcac gccagtcggc cgcgtcggcg atcagcccgg
    16141 acaccgtcct ggagatcagc acgcccacca gcaggccgct catgaccgtg ctcaccaccc
    16201 ggccacgctg gtccggcggc gccagctccg cggcgaacgg caccagtacc tggaccgcga
    16261 cggaggtcac cccgacgatc gcggccgcca cgacgaacac cgcgtacccc gatgccaccg
    16321 ccatcgtgac catgccggcg acgttgcaga tcagcatcgg catcagcagg ccgcgccgct
    16381 ccagcaggtc gccgagcggc accagggtgg ccaggccgat cgcgtagccg atctggatca
    16441 gcgagacggc gagcccgatg gcccggtccg acacgtgaaa cgcctccgcg agcgcgtgct
    16501 ccagcggcac cgcgtagtac agattcgcca cgacggtgcc caccgcgacc gtcaacaaga
    16561 tcagtgttgt gcgccgcaag gcaggtgtga tctgcgcagg cgcgattgcc agtgccattg
    16621 agtcccccaa ccacaacgtt ggggttgcac tttagccggg gcgattcgga acgtcaacga
    16681 tcacgttgga gttagactga ccgggtggcc tgggacaccg aacagacgcg caggaggctc
    16741 aaggaagcgg cgaccgagga gttcgccgcc aacggtctca acggcacgac ggtggagcgc
    16801 atcgcccgcc gggcctcggt gaacaaggag cggctctacc actacttcgg cgacaaggag
    16861 cagctctacg ccgcgatcct caacgacgaa ctggtccgga tcgccgaggc cgttcaactc
    16921 ccctcggccg aagacatgga cgtcggcgag ttcgccggcc gggtgttcga ctaccactcc
    16981 agccacccgc acctggcccg gctgctgcac tgggagggac tgtcctacgc gggcaagatc
    17041 ccgctccagg agaagcgcac gccgtactac acggccaagg tggacgccat caaggcggcc
    17101 cagcgcgccg gcgggatcac cgacgagctg gaccccgccg atctcgcctt catgctgatc
    17161 gcgctcgcgg cgtggtggtt cgccgtgccg caggtcgtgc agatgctgac cggacagacc
    17221 ggcgacgatc cggccgaccg cgccaaacag cgcgccgccg tggtcatcgc ggcccgccgg
    17281 ctcgcccacg acccaccccg gtaagccacc gagaagccgc tgtcccgcgc cagggctctg
    17341 ccgaccaacg ccgtgccacc cgaagcttga caaccgcgcc ggtgcccgtt cgcgtacttt
    17401 agcccgctaa agtacgtcag tcaccgagaa agcccaggtc agccgtgatc aacaggtgac
    17461 cgagaacgtg aaggtggtgc acgtagggcg gcgcgcggtg atggggccac cttcacgggt
    17521 cgctcagcgc gctttcagac gactccgtca cgcacggccc gtgcgacggc gagcgtgcgg
    17581 ttggggcagt cgagcttggc caggatgttc gcgaccaggc gtttcgcgcc gtgctcggag
    17641 atgcgcagcc gccgggcgat ctgcttgttg ctcaggcctt ccacgagcag cgccagcacc
    17701 tgacgctcgc gcggtgtcag gcgcggcgcg gcgctcgccg cggtcgcgcg ctgccgcagg
    17761 atcgccggca gccaccgggc cagccccgag ggcagcgacg acgcgccgtc cgtaccgcac
    17821 agcgcgttgt gcagggctcg ttcgtccagg tcgtcgaccc cgagatagcc gacaccgtcg
    17881 agcacccagc ccggttcgac cagttcgaga tcaccgtcgg cgaccagcag caggactctc
    17941 atcccggcgc gcacggccgc gcggagatcg gcgacggtcg cgccgtcgac ctcggccaat
    18001 ctggcgatca ggacactccg gccgcgcgcc gtgtcgagcc cgccgcgcag gtcacgccga
    18061 gaggcgacct cggtcatccc cagcgcgtcg agcatcttct ccagaccgcc gcgcaacagg
    18121 tcgttgcgca tcgcgacggt gatcggaaga gtgctcgatc tgatggccgc gcgcctgcca
    18181 ctgcaagtca tggtcttccc ccaaagccca gttccccaga gccgaggccg agcacggcgc
    18241 gcaagccggt gtcccccacg cacctctgtc gcgtccgcgt cggcctcgga tctccaactc
    18301 taccgttgga tggcgcgtga gaatacccga aaacgtcggt aattccgttt ctcggcgtgc
    18361 cgttacaact ccgggcctcg gctgcgcagg tcgtcgaccg tggacatcgc gtcacgcagt
    18421 tcgtccagcc aggactcggc gtgctcgccg accagccgca ccgcccaggc cagcgcctcg
    18481 gaacgagaac gcgcgacacc ggcgtccacc agcgtgtcca gcaccagccg ctcgggctga
    18541 cgcagccgcg tcatcaccgg tacggagatc gtggtgaaca gctcctcggt cgagccgagt
    18601 ttcgcgcccc acgcgacctt gcgctggtag cggtgctcgg cctggcgcgc gatctcgatc
    18661 cgctcgtccc gcgtctgctc gcgccagcgg ctgatccgcc cggactcggc ggccgaccgc
    18721 gcggcctcgt cgtcgaactc gccggacagt tccggcagct cgccgaccag gatgatctcc
    18781 tcccggtcga ccatcacgac cggcgcgccg gtgaaccact cgtccggcag ccggccctcg
    18841 aaccacgccg ccgcgtcgtc cgccgacggc agatcggcct gctgccatcc gcccttgccc
    18901 cggcctcgtc cgtgcccgtg ccatcctcgt cgcatcgcca tctcctcgat tacacgatta
    18961 catcgatacc gaagctacgc cgattctcgg tgactggcac gagtgttcgc tggcggtgga
    19021 caggtcagcg gcgcagcgcc tccgccagtt cgccggccgt cccgaccggg cggtcgcaca
    19081 cgtaaccccg gcacacgtac gccgccgggc catcgtccag cagcggccgg ccggccagca
    19141 acggcacacc gtccgcgtcc ggctccccgg cgagcacgac cgcgccgccg tgcgcccccg
    19201 ccaccgccga cgcgcgcagc tcggccgtgc gcgcgtcacc ggcgtccccg accacggcca
    19261 cctgcaccgg gccgagcgtc agcgcctcgg cgacgctgag ccagtgcccg gcgaaccggg
    19321 gcgcgcggga gatcagctgc cccgcccgcg cgacggccag ctcggccgcc tcgcggtacc
    19381 ggctcgcggc gtccggcccg gccagcaccg cgcccagcag cagcgcgctc gccaccgccg
    19441 acgcgccgga cgggctggcg ttgtcccccg gatcggacgg ccgccacacc agcgcctcgg
    19501 cgtccgccgc cgtgtcgtgg aacgcgccgg gcacctccgg gtcggcgaag gactccagcg
    19561 cggtgtccag cagcccgagg gcggcggcga gccagcgcgg cgagccggtc gcctggtgca
    19621 gcacgagcag gccctcggcg aggcacccgt agtcctcgag cacactggcc gcgtcgccga
    19681 cgacgccgtc cttggaggtg cgccgcagcc ggccgtccac gagctgggtg tccagtaccg
    19741 ccgccgcggc gcgcgcggcc gcgatggtcc actgtggacg gtcgaacgcg acgccggcct
    19801 cggccagcgc ggcgatcgcc agcccgttcc aggccgccac caccttgtcg tcgcgggccg
    19861 gctgcgggcg ggcgcggcgg gcgccgaaca gccgctcgcg cacccgcgcg tagcgcgtct
    19921 cgtcctccgg cgtggcgagc agccgcagtg tggaggagcc gtgctcgaag gtgccttcct
    19981 cggtcactcc gaacacctcg gccgcccagg cgccgtcgtc cgcgccgagc acctcgacca
    20041 gctgcgccgg cgtccacgcg taggtgagcc cctccacgcc gtcggtgtcc gcgtccagtg
    20101 acgccgcgaa cccgccgtcc acagtggaca gatcgcggag caggaactcc gcggtgccct
    20161 cggccaccga gcgcgccagc gccgaaccgt tgagccgcca cagatgtgtg tacacgcgca
    20221 gcagcaatcc gttgtcgtac aacatcttct cgaagtgcgg caccacccag gaggcgtcca
    20281 ccgagtaccg ggcgaacccg ccgccgagct ggtcgtagat tccgccgcgg gccatcgcct
    20341 cggccgaacc gtccaccatg gacagtgcgg agatcgagcc ggtgcgctcg tggtggcgca
    20401 gcaggaactc cagcaccatc gacggcggga acttcggcgc agcaccgaat ccgccgttgc
    20461 cgcgatcgta ctcgccgagc agcgagtcca ccacgccgtc cagcacctcg ttgtccacag
    20521 tggactcctg cagcggcttg gtctgctcgc gcaggtggcc gacgatcgcg gcggccgcct
    20581 cgtccagctc agaccggcgg ctggtccacg cgtcgtgcac cgcgtccatc aactggcgga
    20641 acgacggcat gccggggcgc gccgcgggcg gatagtaggt gccacagtgg aaaggctcgc
    20701 cgtcggcggt gaggaagcag gtcatcggcc agccgccgtg gccggtcatc gcctgcgtcg
    20761 cggtcatgta gacggcgtcg acgtccgggc gctcctcgcg gtccaccttg atgttcacga
    20821 accgcgcgtt catcacctcg gcggtggccg ggtcctcgaa cgactcgtgc gccatcacgt
    20881 ggcaccagtg gcaggccgcg tagccgaccg acagcagaac gggcacatca cgtcgccgcg
    20941 cctcggcgaa cgcctcctcg ccccacggcc accagtccac cgggttgtcc gcgtgctgc
//
