LOCUS       NZ_SGWQ01000001        22592 bp    DNA     linear   CON 10-APR-2024
DEFINITION  Herbihabitans rhizosphaerae strain DSM 101727 Ga0310478_101, whole
            genome shotgun sequence.
ACCESSION   NZ_SGWQ01000001
VERSION     NZ_SGWQ01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Herbihabitans rhizosphaerae
  ORGANISM  Herbihabitans rhizosphaerae
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Herbihabitans.
REFERENCE   1  (bases 1 to 1096878)
  AUTHORS   Goeker,M.
  TITLE     Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing
            the most valuable type-strain genomes for metagenomic binning,
            comparative biology and taxonomic classification
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1096878)
  AUTHORS   Goeker,M., Huntemann,M., Clum,A., Pillay,M., Palaniappan,K.,
            Varghese,N., Mikhailova,N., Stamatis,D., Reddy,T., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-FEB-2019) Prokaryotic Super Group, DOE Joint Genome
            Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.12.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 226.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004216555.1-RS_2024_04_10
            Annotation Date                   :: 04/10/2024 19:27:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,690
            CDSs (total)                      :: 6,628
            Genes (coding)                    :: 6,561
            CDSs (with protein)               :: 6,561
            Genes (RNA)                       :: 62
            rRNAs                             :: 3, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2 (5S)
            tRNAs                             :: 54
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 13 of 67
            Pseudo Genes (incomplete)         :: 59 of 67
            Pseudo Genes (internal stop)      :: 5 of 67
            Pseudo Genes (multiple problems)  :: 9 of 67
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:31:17
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 163022
            Orig. end                         :: 185614
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            SGWQ01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22592
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="1"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22592
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22592
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12592](+)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12592
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            566..1807
                     /locus_tag="EV193_RS00840"
                     /old_locus_tag="EV193_101169"
     CDS             566..1807
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EV193_RS00840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EV193_101169"
                     /product="DUF2029 domain-containing protein"
                     /protein_id="WP_130341995.1"
                     /transl_table=11
                     /translation="MSVWKKASVLTAIVMTAFAVRLIFFDYESADYTGFVRNWYEFIEQ
                     NGGFAAFEHQFANYNVPYLYLLAGATYLPIPPLVAVKLISIVFDGVLGWYAYRLLATRY
                     PNGWVAPGGAVVTVLLPTVVLNSSMWAQADSIYVAFSVGGLYYLVQRRPWLACVSFGLA
                     FSFKLQAVFLFPVLLLLAVRKWLPWRALLAIPGVYFMLGVPALLAGASPSALLSIYLEQ
                     ADSYGQLTMNAPNAYQFLTVDSSETLRIAGVLVTGVVVLALIVAARRVELTPTRIVLAA
                     TVSALLVPFLLPSMHERYFYTADVLTVIAAFWLPRELWYAPVLTQFASLFSYLPFLSMS
                     GGPGRVIMGGPPPGAGPGIVVTPQGGPGGLSPAVIDFRILAAAMLVALIGVLAVTWRHY
                     GSQRSQVGARTMVT"
     gene            1804..2310
                     /locus_tag="EV193_RS00845"
                     /old_locus_tag="EV193_101170"
     CDS             1804..2310
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016060.4"
                     /locus_tag="EV193_RS00845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_101170"
                     /product="GtrA family protein"
                     /protein_id="WP_130341996.1"
                     /transl_table=11
                     /translation="MTRTRLGAAPGQRLRMAFARFATASLGATAFSQLVLATLYWIGGT
                     NAVTASTVAFLAGAVPHFLVIRRWAWDRHGHLRWDAVVYTVVTLTAGALVILATTIAER
                     QFAPMIDGRGLRTIVVVAAYVASAVPVFVLKFLVLDKVFRQANDAASSTRVRAPKPEAP
                     GTTSS"
     gene            complement(2235..3746)
                     /locus_tag="EV193_RS00850"
                     /old_locus_tag="EV193_101171"
     CDS             complement(2235..3746)
                     /EC_number="3.4.11.1"
                     /GO_function="GO:0030145 - manganese ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005461745.1"
                     /locus_tag="EV193_RS00850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_101171"
                     /product="leucyl aminopeptidase"
                     /protein_id="WP_130341997.1"
                     /transl_table=11
                     /translation="MPRSPLPTLPTPLPTVEVAGDARRGVPHVVLGRPGEATDDEVTVA
                     LGPGGDALDQEWITSCGATGKAGETHAAPGRTPRWLLGVGDGGPKQWRTAGAALARAVN
                     GRAKSDSDAGRTAARSVQVRFEDGADAEEIAAFVLGVTLGGYGYTVTSEQALPTLRTVR
                     LIVAEDRIAEVTAIVANAVGMAEATAFTRDLANTPSNVKDPAWLASTAARVADGVPGLR
                     ATVRDENWLSDNGFGGVLAVGGGSSRPPRLIELSWRPRGATGPHLVFVGKGITFDTGGI
                     SIKPADGMHLMRTDMAGGAAVISALIAIARLRLPVRVTGLVPCAENHVSGSAYRPGDVV
                     RHYGGQTTEVTNTDAEGRMVLADAIEYARARLKPDHLVDVATLTGAMKVSLGVRTAGLF
                     ATDDALAERVAEAGGRVGEAWWRMPLLEEVADAVHSDIADVRQMPKGPGGIAAASFLRA
                     FVGETSWAHLDIAGPARAEKAYDEVVPGASGFGARTLVELAASFA"
     gene            complement(3834..4001)
                     /locus_tag="EV193_RS00855"
                     /old_locus_tag="EV193_101172"
     CDS             complement(3834..4001)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966491.1"
                     /locus_tag="EV193_RS00855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_101172"
                     /product="DUF3117 domain-containing protein"
                     /protein_id="WP_130341998.1"
                     /transl_table=11
                     /translation="MAAMKPRTGDGPLEVTKEGRGIVMRVPLEGGGRLVVEMSAEEASA
                     LGDALKTAAG"
     misc_feature    4053..4068
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.56"
                     /tool="antismash"
     misc_feature    4055..4069
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.32"
                     /tool="antismash"
     gene            4204..5016
                     /locus_tag="EV193_RS00860"
                     /old_locus_tag="EV193_101173"
     CDS             4204..5016
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012783411.1"
                     /locus_tag="EV193_RS00860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_101173"
                     /product="PaaX family transcriptional regulator C-terminal
                     domain-containing protein"
                     /protein_id="WP_130341999.1"
                     /transl_table=11
                     /translation="MRARSALFDVYGGYLRSRGGSAAIAALVRLLEPLGFGAPAIRTAV
                     SRMVRQGWLAPIRLDDGPGYTLTPRGQRRLDEAGARIYRTRPSTWDGRWHVVVLEDLPV
                     RHARDRLASSLRLLGYGPLGPATWVAPRPSPEIAEVLAGEEVLARVFHGELDGGVDGGD
                     TALATRAWDLDTLGRDYRAFVSEWDERMSEVDGDSPAEAFAASQRLLHAWRKFLFRDPG
                     LPDELLPADWPGHRAARFFDEHTARLAPAAKEFLDDCLNRGGRTRSSA"
     gene            5036..5827
                     /locus_tag="EV193_RS00865"
                     /old_locus_tag="EV193_101174"
     CDS             5036..5827
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: ECH (9-255). E-value: 6.8e-64. Score:
                     207.4. Matches aSDomain:
                     nrpspksdomains_EV193_RS00865_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009949795.1"
                     /locus_tag="EV193_RS00865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_101174"
                     /product="enoyl-CoA hydratase-related protein"
                     /protein_id="WP_130342000.1"
                     /transl_table=11
                     /translation="MSDQVLLTEDAGGVRTLTLNRPDSFNSMTTHLKEELLAALRAAAE
                     DESVRAVVLTGSGRAFCAGQDLKEHVAALTSGDDSPLRTVELHYNPIVETITGMGKPVI
                     AAVNGTAAGAGASFAYACDLRIAARGAKFMMAFAGIGLTADSGASWTLPRLIGYGRAME
                     IMLLGNPVTAEEALNIGMVNQVVDDDAVLSTAVALAGRLATGPTSAYAEIKSAMLTAAS
                     ADLSAALAHEGVGQNKLGATADHREAVDAFVNKRKPTFTGH"
     aSDomain        5063..5800
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EV193_RS00865_ECH.1"
                     /evalue="6.80E-64"
                     /label="EV193_RS00865_ECH.1"
                     /locus_tag="EV193_RS00865"
                     /protein_end="255"
                     /protein_start="9"
                     /score="207.4"
                     /tool="antismash"
                     /translation="DAGGVRTLTLNRPDSFNSMTTHLKEELLAALRAAAEDESVRAVVL
                     TGSGRAFCAGQDLKEHVAALTSGDDSPLRTVELHYNPIVETITGMGKPVIAAVNGTAAG
                     AGASFAYACDLRIAARGAKFMMAFAGIGLTADSGASWTLPRLIGYGRAMEIMLLGNPVT
                     AEEALNIGMVNQVVDDDAVLSTAVALAGRLATGPTSAYAEIKSAMLTAASADLSAALAH
                     EGVGQNKLGATADHREAVDAFVNK"
     gene            complement(5848..6576)
                     /locus_tag="EV193_RS00870"
                     /old_locus_tag="EV193_101175"
     CDS             complement(5848..6576)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013003.4"
                     /locus_tag="EV193_RS00870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_101175"
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="WP_130342001.1"
                     /transl_table=11
                     /translation="MAVRWAGRAPKTKLDRQAPDLAPRDRLSVENELRKTNLEIIGAVV
                     LIIGVAFTFLEWRATKDQLTVNQETQSSDRLVKTIGQISSSEQAEQVGGMYGLRNLAVD
                     AAAKGDDSYYRVLDQTLSAYIRQHVPCLASCPPKPGGADPRATYTVQVALSLLGDKEGR
                     LDRDKMNQARQKEMVDLRGVDLREMNLRGLYLGYVNFQGSNLSSSDLTDANVSNSDLRR
                     VVLNNVIGRESVIADGTRWP"
     gene            complement(6645..7532)
                     /locus_tag="EV193_RS00875"
                     /old_locus_tag="EV193_101176"
     CDS             complement(6645..7532)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013465.4"
                     /locus_tag="EV193_RS00875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_101176"
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="WP_165401162.1"
                     /transl_table=11
                     /translation="MVNVWALGWLVEQIGGELVGEVKVFESKPHEPPAQGDIDQMRTAD
                     SVLYIGNLSAEAATALGARAKADPERFQDISALDNIALLTAPPELGDDRLPGNRDPHVW
                     LDPAGRMVTVARKVARSLVKAVEQRPELADARARHTDGINQRLGQATTKLVEIRDRLKL
                     KAAGCRNKTIVPEHPAYAYLVEWLELKQLPVTRISSKTLPSAQAEERRALLRTLWQTEG
                     HRTLFLEHSKGPQGKNPDAERKEIDELADQFGAIFEYLSSLESPPEPKPGESERKYPEA
                     LEYVVDQVKKGLKC"
     misc_feature    7675..7690
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.66"
                     /tool="antismash"
     gene            complement(7769..8317)
                     /locus_tag="EV193_RS00880"
                     /old_locus_tag="EV193_101177"
     CDS             complement(7769..8317)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020660691.1"
                     /locus_tag="EV193_RS00880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_101177"
                     /product="GtrA family protein"
                     /protein_id="WP_242613074.1"
                     /transl_table=11
                     /translation="MHDTTGERRPITDRFSDFCAAVIRRLPFGLSRIVPPSLLGFAIIN
                     GFTFSVDIGLLSLMKVGLGWPSGIAFTIGYVIAFGLAYYLNRTFNFHSHAPVGPQALLY
                     AVAVLINYLAFILGVGAGLTSLGVHYLLARLLAGSCEAVYMYSVMRWVIFRDMLKQAEP
                     HHEGATQGAEGGTRAVSGR"
     misc_feature    8318..8332
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.83"
                     /tool="antismash"
     gene            complement(8451..9029)
                     /locus_tag="EV193_RS00885"
                     /old_locus_tag="EV193_101178"
     CDS             complement(8451..9029)
                     /EC_number="3.2.2.20"
                     /GO_function="GO:0008725 - DNA-3-methyladenine glycosylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003086568.1"
                     /locus_tag="EV193_RS00885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_101178"
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="WP_130342004.1"
                     /transl_table=11
                     /translation="MTDGSAVVGEDGRARCSWGGSTPDYAAYHDTEWGVPLHGDAALFE
                     RLCLEAFQSGLSWLTILRKRDGFRRAFADFDPAAVAKFGDDDVARLMADTAIVRNRRKI
                     DAAIGNARALLELDEPLDTLLWSFAPPAEGRTRPSSMDDVPAVTPESTAMAKELKRRGF
                     AFVGPTTCYALMQATGMVDDHIAGCWRAT"
     gene            complement(9026..9343)
                     /locus_tag="EV193_RS00890"
                     /old_locus_tag="EV193_101179"
     CDS             complement(9026..9343)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007025339.1"
                     /locus_tag="EV193_RS00890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_101179"
                     /product="DivIVA domain-containing protein"
                     /protein_id="WP_130342005.1"
                     /transl_table=11
                     /translation="MTTALIYLVVMILVAAVVFVLASVVFGRGEELPPLPPGASPTRLP
                     ASGVTGEDLRDLRFQLVVRGYKMSEVDWVLQRLGGELDSLRARVAELEEQVAETDHEAP
                     R"
     misc_feature    9498..9513
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.03"
                     /tool="antismash"
     gene            9526..9798
                     /locus_tag="EV193_RS00895"
                     /old_locus_tag="EV193_101180"
     CDS             9526..9798
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EV193_RS00895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EV193_101180"
                     /product="hypothetical protein"
                     /protein_id="WP_130342006.1"
                     /transl_table=11
                     /translation="MRNLTSRVAAVFLAVAATFSIGTTALATPATPPSALSPIPSDGDP
                     SECPPPPGGPVPQSLPQSAGDEPGQGEPGQGDPGEDDQCGAFAWG"
     misc_feature    9631..9633
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            10001..12592
                     /gene="lanKC"
                     /locus_tag="EV193_RS00900"
                     /old_locus_tag="EV193_101181"
     CDS             10001..12592
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF038151.1"
                     /locus_tag="EV193_RS00900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_101181"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_130342007.1"
                     /sec_met_domain="micKC (E-value: 3.9e-235, bitscore: 778.7,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 2.3e-12, bitscore: 42.9,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2.3e-05, bitscore:
                     19.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDQMLSLYCVADESFFDRPDRMDDGATRFAVADRPAPTNWGRGES
                     DLWVGLASPHGRPPAQGWKIHVSVTREDAERCLDIVWDYCAANDLDFKFLRSADAMLIL
                     NAKYARRGSSGKLVTLYPRDDAQLAHALTELDARLSGLSGPYVLGDLRIGKGPLYVRYG
                     AFDEMWCHDGGDDPALAIADPRGELIPDRREPVFTVPEWAAIPDVLRPHIEARTKASAA
                     DFPYRVTEALHFSNGGGVYVGEDSSGTKVVLREARPHAGLDRHGTDAVQRLRREHDTLA
                     RLSGLDCVPHVLDHRVVQDHHFLVEEFIEGTTLLRAIQTRSPSLAPGASSEEITGQIRD
                     YRDWAVDVLERISTALRAVHSRGVRFGDLHPANILIQPDGEVVFVDFEFAADLTDDVPP
                     GLGAPGFIAPPGLTGAEVDLYALNCLRVYLFTMLTPLTDLDRAKAVTLAAEACRDNAMP
                     TEFADRFVAATHPAGATPAPDRAADLFADPSWPTIRDSLVAGILDSATPDRTDRLFPGS
                     PQQFRTGGFDLAHGAAGVLLALHRVGAPVADEHVGWMVRAVQDAPTRPALGLYNGPHGV
                     AAVLDELGRRDEALDVLDVARAFDRLPASDTLYGGHAGRAVNLLHFARATGDQELRAAA
                     LELGHDVAARAASGTWPTGRGLLRGPSGVALLLLHLHEETGDARYLDLAWQGLRRDLDN
                     GETLPDGTFQLRAEHRAVPYLDGGGSGVALVLHEFTRHHRDAETDRIMAGIRRGCAVPF
                     VYLPGLFSGRAGFVATLARLGTDRDVLREHVHRFGSHALSRNGNLVFPGDQLLRLSLDL
                     ATGSAGILLALHAVFDGTRAVLPYLETRSPTPVRTREGGEQHDQHPRPAGP"
     gene            12750..13976
                     /locus_tag="EV193_RS00905"
                     /old_locus_tag="EV193_101183"
     CDS             12750..13976
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF017760.4"
                     /locus_tag="EV193_RS00905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_101183"
                     /product="MFS transporter"
                     /protein_id="WP_130342008.1"
                     /transl_table=11
                     /translation="MGETITAVPLRRNRDFHLIWVGGTLAGLGSRMAALALPLLVLQQT
                     GSTAKAGLVGSISAATLLIAIIPAGAVADAVERHRLMRYCELAGSLIAAALAATVLAGS
                     PAMPAVVITSVAVAILGSLYAPAAIGLLRAAVPADQLGLAMSRLQARNAATQIAGPLAG
                     GALFGVAPALPFAVQAGAMFVSFGCLLTIRTRSRPAPDATRLTPRQITAGFRFLWQQRY
                     LRTILIVYGAGMNATFSALMLVTITASAHADPSGRSSGLIVALASIGSLAGALAAPRLR
                     SADAPHTVLTLTSWCIGAATLLFVVVTQPLAQGLLLAVVLFLSGVANVAFETEQARLTP
                     TDLAGRVEAAAIFISMIAQPLGPLGGGLLAEAYGPATAFLVIGALIAIVAGFLTLSFRR
                     INSDTTGRQ"
     gene            13978..14268
                     /locus_tag="EV193_RS00910"
                     /old_locus_tag="EV193_101184"
     CDS             13978..14268
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EV193_RS00910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EV193_101184"
                     /product="hypothetical protein"
                     /protein_id="WP_130342009.1"
                     /transl_table=11
                     /translation="MGRTVRWLGAVAAAGTVALSGAGVAAATPAPAVSGYYTGFGSGSS
                     QQLALWSAQDQAYWKASIGGFRRFDCRVTYSNVTGGPYSYSAYVNLYCWRP"
     gene            complement(14273..15271)
                     /locus_tag="EV193_RS00915"
                     /old_locus_tag="EV193_101185"
     CDS             complement(14273..15271)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EV193_RS00915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EV193_101185"
                     /product="hypothetical protein"
                     /protein_id="WP_130342010.1"
                     /transl_table=11
                     /translation="MALTDLGFTKQQELAYRALVDDPTMSLADVAGLIGCGRNTAREIL
                     DGLVELGVAKVARDGDLGVALAHPVSALGDLIERREDELLRMHRRVGDTRAEVAELGMR
                     FAGRAGLVADPDSGIERVTDLEVLRERLEELAFFTRSTVYAVQPGGALSEEMLNASRPL
                     DLRALRRGVDMRIIYNTTFLADQYCRDYLRDIVAAGAAVRITDDSLDRMIIMDKRVVVV
                     PIDPDRSHLGGQIVRQPGLVMGFMRLFDQLWDAARPLPWADEEDERAFVPTDEDRQVLA
                     LLASGSTDETAARAAGISVRHLRRRVAKLMERLDAGSRFEAGVEATRRGWI"
     misc_feature    15377..15397
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 21.31"
                     /tool="antismash"
     gene            complement(15538..16251)
                     /locus_tag="EV193_RS00920"
                     /old_locus_tag="EV193_101186"
     CDS             complement(15538..16251)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF038403.1"
                     /locus_tag="EV193_RS00920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_101186"
                     /product="permease prefix domain 1-containing protein"
                     /protein_id="WP_130342011.1"
                     /transl_table=11
                     /translation="MAVPDISRGVNRGMTGHDIDDYLAELDGRLRGPASIKADLLTEAR
                     DGLVDAAEAYASSGKPEAEARRLAVADFGPVDQIAREYQAELGVAHSLRTLRTVLLVPL
                     AMNLFWELNRQLWLGSWSNMNWTAPDWFLVIARFNDVAVWMITGLALLGLIASRYMTRT
                     SVEPWRVGRHGGIIAMLAATVHLAALLAMVAGSAAFGFGVTVTPFPLLLASLTALVVAV
                     RLVLLARRSLSLCLV"
     gene            complement(16233..16571)
                     /locus_tag="EV193_RS00925"
                     /old_locus_tag="EV193_101187"
     CDS             complement(16233..16571)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009951435.1"
                     /locus_tag="EV193_RS00925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_101187"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_130342012.1"
                     /transl_table=11
                     /translation="MKADALRGHLDALLLATLDGGKLHGYAIIEALQLRSGGALDLPTG
                     TVYPALRRLERAGYVASEWSTVGGRKRRTYRLTATGERSLAKERTAWREFTTAIDGVLG
                     GGPWPSPT"
     misc_feature    16666..16682
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.65"
                     /tool="antismash"
     gene            16717..17988
                     /locus_tag="EV193_RS00930"
                     /old_locus_tag="EV193_101188"
     CDS             16717..17988
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_component="GO:0070069 - cytochrome complex [Evidence
                     IEA]"
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0019646 - aerobic electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016331436.1"
                     /locus_tag="EV193_RS00930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_101188"
                     /product="cytochrome ubiquinol oxidase subunit I"
                     /protein_id="WP_130342013.1"
                     /transl_table=11
                     /translation="MSDAVDLARIQFATTTSFHFLFVMLTLGLVTLVAITQTRYTLSGN
                     ENRRETLSRMTRFWGHLYVINYALGIATGIVMEFQFGMNWSGLATVVGDVFGAPLAIET
                     LVAFFLESTFLGLWIFGWGRLNKWLHLALIWLTALTAYASAFWIMVANAFMQNPVGYEV
                     IGDGGDATVRLTDFGALLSNPMFGDALLHVVAGALVTGGVFMAGISALHFLRRTTEVEF
                     FQRSLRLGLVTAAIAAPVLIGFGFAQFSTIDELQPGKVSEGGDAAAAAQAELVARYGPG
                     DYITPEWANGLFGQMIEFGFLLTLALFAMVLMLFRGWLFRRRLPLRLLVVMIPIPFVAA
                     ISGWLFREVGRQPWLVYGLLRTEDAASHVSVGSMWVSLVVFTALFAALAVADWVLIARV
                     ARRGPAPAEAALPPRPVTPEPVAL"
     misc_feature    complement(16730..16743)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.25"
                     /tool="antismash"
     misc_feature    17992..18007
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 18.61"
                     /tool="antismash"
     gene            18000..19004
                     /gene="cydB"
                     /locus_tag="EV193_RS00935"
                     /old_locus_tag="EV193_101189"
     CDS             18000..19004
                     /EC_number="7.1.1.-"
                     /GO_function="GO:0016682 - oxidoreductase activity, acting
                     on diphenols and related substances as donors, oxygen as
                     acceptor [Evidence IEA]"
                     /codon_start=1
                     /gene="cydB"
                     /inference="COORDINATES: protein motif:HMM:NF014386.4"
                     /locus_tag="EV193_RS00935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_101189"
                     /product="cytochrome d ubiquinol oxidase subunit II"
                     /protein_id="WP_130342014.1"
                     /transl_table=11
                     /translation="MDTLLLVVIAMLFAGYFALAGFDYGTGLLYRTLGTDEPERRRVLG
                     TVGPFFLGNEVWLVAAIGLMIGAFPRWEGELLSGAYPIVVAILVGLITFTAAFQLRSRR
                     DGARRRVWDTLVTGGAAVTVAGWGLLLGNLVRGLPLENGRPAGDVLDLFSPYAITWGVG
                     FVALFGLHGAAFIAMRTAGKLAERARRAGRACAGPAVLFVVAAGVGGMLSDEVGAAVTR
                     PWLAIGGAAVFAALLMTASSSLARYRPRIAFACTTTVCALLMPLLLAARYPNLLTSTVD
                     SKVLTVEQGVAGGATLDVLGWVALAVIPLVLLLQWTVWWGNRRKVDERTPLFW"
     misc_feature    complement(18016..18036)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.06"
                     /tool="antismash"
     gene            19011..20603
                     /gene="cydD"
                     /locus_tag="EV193_RS00940"
                     /old_locus_tag="EV193_101190"
     CDS             19011..20603
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0055051 - ATP-binding cassette (ABC)
                     transporter complex, integrated substrate binding [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0033230 - ABC-type cysteine transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0033228 - cysteine export across plasma
                     membrane [Evidence IEA]"
                     /codon_start=1
                     /gene="cydD"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009072876.1"
                     /locus_tag="EV193_RS00940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_101190"
                     /product="thiol reductant ABC exporter subunit CydD"
                     /protein_id="WP_130342015.1"
                     /transl_table=11
                     /translation="MIDKVLLHEFPRLRRYLGTLAIFASLTAVLVLAQAEVLARLLSGG
                     ASWTLFALAAAVLAVRAISLWWQGNLASRVAARVQADVRSRVLRSAAAPGGAPSGEVST
                     LVTRGVDAIEPYVAGYLPTVLVSVTVPLAVVARLFFVDWPSALIIALTLPLVPLFAALV
                     GAHTRRRTERQYALLSRLGGHFLDVARGLRTLMLHGRARAQSDTVRRMAGEHASATMGT
                     LRVAFLSALVLELVATLSVALVAVPVGLRLLTGGVTLLTALLVLLLAPEAYLPLRAAGA
                     RFHASAEGLAVLRRAIDLEPISVPHKGKRVDARTAVIRFEKVTVRYPSRPEPALNGVSL
                     TVRPGERVVLVGPSGAGKSTLIGLLLGLVEPDEGQVTVDGVDLRDIDLDWWRTQLSWVP
                     QRPWLFAGSLADNVRLSRPDATDDEVRAAAHAAGLDRVFAARGDSALDERGSGLSSGER
                     QRVALARALLRTDSPIALLDEPTARLDVRTEHAVLSGWRRLTAGRTSIAVAHRPALLAG
                     AHRVVRVHEGRTA"
     gene            20600..22177
                     /locus_tag="EV193_RS00945"
                     /old_locus_tag="EV193_101191"
     CDS             20600..22177
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020643547.1"
                     /locus_tag="EV193_RS00945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EV193_101191"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_130342016.1"
                     /transl_table=11
                     /translation="MSPLWTVFGARRAALLGAGLTSAAAELAGVTLTATAAWLIARAAE
                     MPPIGALTVAIVAVRTLAIGRGGLRYAERLAGHSAVLRCVGELRGRVYDTLLARRTAAR
                     DADLLTRVVSDVDATQDAVLRCAIPMAVGLTVTLTAGVAAAFADPLVAAVVLAGLVLTC
                     VVLPAGSLALARRTAAATAPGRARLAEQTADLVHGAAELTVFGAVPDRLRDADTTVRRL
                     ARSQRGTAAVTAVLGAGAVVVQAVTCLAVIMLGIARDLPGPVVAAIALGALAAIETTIP
                     LAGAAARWAEVSTSVRRLGELLTGPSAEPSTVEGVRLEVPPGARIGVVGPTGSGKSTLL
                     DGLARERVACGVLADAHLFHTSVRHNIAMAKPGATQQDLDRVAALVRLDEWIASLPDGW
                     DTVLGESGATVSGGQRQRLLLARALLAAPAVLLLDEPVEGLDHAMADAVLADVLAASDT
                     VVLVTHRLAPLAHGFDEIVVLDGGRIAQHGTHEELLARDGYYRQAWLAERMLESGCGTN
                     DPSRTLSA"
     misc_feature    22278..22291
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.43"
                     /tool="antismash"
ORIGIN
        1 acgcggtgga cccgcacgcc caggtggtgc tgtgcgcggg cgcgccggac accgaggaga
       61 tcgccacgtc gacgtcggcc gcggtgtccg agctggccgc cgcgcgggac ggcgtgttct
      121 gggtacggga gatgctgccg cccgaggatc tgcgccagat gctcagtgcc gcaacggttt
      181 tcgtgtgccc gtcggtgtac gagccgctgg gcatcgtgaa cctggaggcg atggcgtgcg
      241 gcaccgccgt ggtggcctcc gacgtcggcg ggatccccga ggtggtggac gacggggtga
      301 ccggggtgct ggtgccgttc gacgagcacg atcccgaggg tttcgccgcg gggctcgcct
      361 ccggggtgaa ctcggtgctg gccgatcggg cgctggcggc gcgcatgggc gaggcggggc
      421 ggtcgcgggc ggagcgggat ttcgcgtgga cgtcggtggc cgagcagacc gtgcgggtgt
      481 acgaatcggt gctgcgcggc tgacgcacag ctcgcaccca ggtgacacac agcgcgttcc
      541 gaattcgggc ggccacggtt gtcccgtgtc tgtgtggaag aaagcgagcg tcctgaccgc
      601 cattgtgatg accgcattcg ccgtgcggct gattttcttc gactacgagt cggcggatta
      661 cacgggattc gtgcgcaact ggtacgagtt catcgagcag aatggcggat tcgcggcatt
      721 cgagcaccag ttcgcgaact acaacgtgcc gtatctctat ctgctcgccg gcgcgacgta
      781 tctgccgatt ccgccactcg tggcggtcaa gctgatctcg atcgtgttcg acggcgtgct
      841 ggggtggtac gcgtaccgcc ttctcgcgac cagatacccg aacgggtggg tggcgccggg
      901 cggtgcggtg gtgaccgtgc tgctgccgac ggtggtgctg aacagctcga tgtgggcgca
      961 ggccgactcg atctacgtgg cgttctccgt cggcgggctg tactacctgg tacagcgccg
     1021 accgtggctg gcctgtgtgt ccttcggctt ggcgttctcg ttcaaactgc aggcggtgtt
     1081 tctttttccc gtgctgttgt tgctcgctgt acgcaaatgg ctgccgtggc gcgccttgct
     1141 ggcgattccg ggcgtctatt tcatgctcgg cgtacccgcg ctactggccg gcgcgagccc
     1201 gagcgcgctg ttgtcgatct atctcgaaca ggcggacagc tacggccagt tgaccatgaa
     1261 cgcgccgaac gcgtaccagt tcctcaccgt ggattcctcg gaaacactcc ggatcgccgg
     1321 cgtactggtg accggcgtgg tggtactcgc cctgatcgtc gccgcgcggc gggtcgaact
     1381 gaccccgacc aggatcgtgc tggcggccac cgtgtccgcg ctactggtgc cgttcctgct
     1441 gccgtcgatg cacgagcggt acttctacac ggccgacgtg ctgaccgtga tcgccgcgtt
     1501 ctggctgccg cgtgaactct ggtacgcgcc ggtgctcacc cagttcgcgt cgctgttctc
     1561 ctacctgccg ttcctgtcga tgtccggcgg gcccggccgg gtgatcatgg gcggtccgcc
     1621 gccgggtgcc ggtccgggaa tcgtcgtgac cccccagggt ggtcccggcg gcctgtcgcc
     1681 cgccgtcatc gacttccgga tcctggccgc cgccatgctc gtggcgctga tcggcgtgct
     1741 ggccgtgacc tggcgacact acggttctca gcgatctcag gttggcgcgc gcaccatggt
     1801 cacgtgacgc ggacgcgcct gggggcggcg cccgggcaga ggctgcggat ggccttcgcc
     1861 cggttcgcca ccgcgtccct cggcgcgacc gcgttcagcc aactcgtgct cgccacgctg
     1921 tactggatcg gcggcacgaa cgcggtcacc gcgagcacgg tcgcgttcct ggccggcgcg
     1981 gtgccgcact tcctggtgat ccggcgctgg gcctgggacc ggcacgggca cctgcgctgg
     2041 gacgccgtcg tctacacagt ggtcacgctc accgccggcg cgctggtgat cctcgcgacc
     2101 acgatcgccg aacggcagtt cgcgccgatg atcgacggcc gcggtctgcg cacgatcgtc
     2161 gtggtcgcgg cctacgtggc cagcgccgta cccgtgttcg tgctgaagtt cctcgtgctg
     2221 gacaaggtgt tccgtcaggc gaacgacgcg gccagctcca ccagggtgcg cgcaccgaaa
     2281 ccggaggcgc cgggaaccac ctcgtcgtag gccttctccg cgcgggcagg gccggcgatg
     2341 tccaggtgcg cccacgaggt ctcgcccacg aacgcgcgca ggaacgacgc ggcggcgatc
     2401 ccgccgggcc ccttcggcat ctggcgcacg tcggcgatgt cgctgtgcac cgcgtcggcg
     2461 acctcctcca gcagcggcat ccgccaccac gcctcgccga cccggccgcc cgcctcggcc
     2521 acccgctcgg ccagcgcgtc atccgtggcg aacaggccgg cggtgcgcac gccgagagac
     2581 accttcatcg cgccggtcag cgtcgcgacg tcgaccaggt ggtcgggctt gagccgggcg
     2641 cgggcgtatt cgatcgcgtc ggccagcacc atgcgcccct cggcgtcggt gttggtgacc
     2701 tcggtggtct ggccgccgta gtgccgcacc acgtcgcccg gccggtacgc cgacccggac
     2761 acgtggttct ccgcgcacgg caccagaccg gtcacccgca ccggcagtcg cagccgcgcg
     2821 atcgcgatca gcgcggagat caccgcggca ccgccggcca tatcggtgcg catcaggtgc
     2881 atgccgtcgg ccggcttgat cgagatgccg ccggtgtcga acgtgatccc cttgccgacg
     2941 aacaccaggt gcgggccggt cgcgccgcgc ggccgccagc tcagctcgat cagcctcggc
     3001 ggccgggagg agccgccgcc gaccgcgagc acgccgccga acccgttgtc ggacaaccag
     3061 ttctcgtcgc gcacggtggc gcgcagcccc ggcacgccgt cggcgacacg cgccgcggtg
     3121 gacgccagcc aggccgggtc cttcacattg gacggggtgt tcgccaggtc cctggtgaac
     3181 gccgtcgcct cggccatgcc gaccgcgttg gccacgatcg cggtgacctc ggcgatccgg
     3241 tcctcggcca cgatcagccg gaccgtgcgc agcgtcggca aggcctgctc ggaggtgacc
     3301 gtgtagccgt agccgcccag cgtcacgccg agcacgaacg ccgcgatctc ctccgcgtcg
     3361 gcaccgtcct cgaagcgcac ctggaccgat cgcgcggcgg tgcgcccggc gtcggagtcg
     3421 gacttggccc tgccgttgac cgcacgggcc agcgccgcgc ccgcggtgcg ccactgcttc
     3481 ggcccgccgt cgccgacccc gagcagccag cgcggcgtgc ggccgggcgc ggcgtgcgtc
     3541 tcgcccgcct tgccggtggc gccgcaggag gtgatccact cctggtcgag cgcgtcgccg
     3601 cccggtccca atgcgacagt cacctcgtcg tctgtcgcct cgccggggcg gccgagcacg
     3661 acgtgcggga caccgcggcg cgcgtcgccg gcgacctcga cggtcggcag cggggtgggc
     3721 agcgtcggca gcggggagcg tggcaaggta cctccggact tcgggacttc acgaaacgcc
     3781 gccccggctc cgagtcacgg agtcggggcg ttggtgtggg gacgggtcga gcgtcagcct
     3841 gcggcggtct tcagcgcgtc cccgagggcg ctggcttcct ccgccgacat ctcgacgaca
     3901 agtcgcccac ctccctcgag tgggacgcgc atcacgatgc cccgaccctc ctttgtcacc
     3961 tcgaggggac cgtcaccggt ccggggcttc atggccgcca tagcgtgctc cctccgtcat
     4021 gagcctgccg cccgatcggc aaccgccgat cgggtgagag tcattctccc ctatccactc
     4081 acggcggcga aatcgaaccg atcattcgtg tcgcacgatc actctgtgat cacaatgtca
     4141 tcacagagtc ggtcatgtgg gtgatgtggc gacaatgcgc ggcaacctgc cagactcgcg
     4201 atcgtgcgtg ccagatcagc gctgttcgac gtgtacggcg gatacctgcg ctctcggggc
     4261 gggtccgccg cgatcgccgc gctggttcgt ctgctcgaac cgctgggctt cggcgcgccc
     4321 gccattcgga ccgcggtgtc gcgcatggtg cgccagggct ggctcgcccc gatccgcctc
     4381 gacgacggcc ccggatacac gctgaccccg cgcgggcagc ggcggctgga cgaggccggc
     4441 gcgcggatct accgcacccg accgtccacc tgggacggcc gctggcacgt ggtggtgctg
     4501 gaggacctac cggtgcggca cgcgcgcgac cggctggcgt cctcgctgcg gttgctcggg
     4561 tacgggccgc tggggccggc cacctgggtg gcaccccgcc cgtcgccgga gatcgccgag
     4621 gtactggccg gcgaggaggt gctcgcccgg gtgttccacg gcgagctgga cggcggtgtc
     4681 gacggcgggg acaccgcgct cgccacccgc gcgtgggacc tggacacgct gggccgcgac
     4741 taccgggcgt tcgtgtccga atgggacgag cgaatgtccg aagtagacgg tgactcgccg
     4801 gccgaggcgt tcgccgcgtc gcagcggctg ctgcacgcgt ggcggaagtt cctgttccgc
     4861 gatccgggcc tgcccgacga gctgctgccg gccgactggc cgggacacag ggcggcccgg
     4921 ttcttcgacg agcacaccgc gcggctcgcg ccggcggcca aggagttcct ggacgactgc
     4981 ctcaaccggg gcggccggac caggtcgagt gcgtgacccg acacggaggt tgatcttgtc
     5041 tgaccaggtg ctgctgaccg aggacgccgg cggtgtgcgc acgctgacgc tgaaccgccc
     5101 ggattcgttc aactcgatga ccacgcacct caaggaggag ctgctcgccg cgctgcgggc
     5161 ggcggccgag gacgagtcgg tgcgcgcggt cgtgctcacc ggatccggcc gggcgttctg
     5221 tgccgggcag gacctcaagg agcacgtggc cgcgctgacc tcgggcgacg actctccact
     5281 tcggacggtc gagctgcact acaacccgat cgtggagacg atcaccggca tgggcaagcc
     5341 ggtgatcgcc gcggtgaacg gcaccgcggc cggcgccggc gcgtccttcg cgtacgcgtg
     5401 tgacctgcgg atcgccgcgc gcggcgcgaa gttcatgatg gccttcgccg ggatcgggct
     5461 gaccgcggac tccggcgcgt cctggacgtt gccgaggctg atcggctacg ggcgcgcgat
     5521 ggagatcatg ctgctgggca acccggtgac cgccgaggag gcgctgaaca tcgggatggt
     5581 caaccaggtc gtggacgacg acgcggtgct gtccacggcg gtggcgctgg ccggccggct
     5641 ggcgaccggt ccgacctcgg cgtacgcgga gatcaagtcg gcgatgctga ccgccgcgtc
     5701 ggccgatctg tccgccgcgc tggcgcacga gggtgtcgga cagaacaagc tcggcgccac
     5761 ggccgatcac cgggaggcgg tcgacgcctt cgtgaacaag cgcaagccca ccttcaccgg
     5821 ccactgaccg cggcggcacc cggcgggcta cggccaccgg gtgccgtccg cgatgacgct
     5881 ctcgcggccg atcacgttgt tcagcacgac tcgccgcagg tcggagttgc tcacattggc
     5941 gtcggtgaga tcggacgagc tgaggttgga tccctggaag ttcacgtatc ccaggtacag
     6001 gccgcgaagg ttcatctcgc ggaggtccac accacggagg tcgaccattt ccttctgccg
     6061 tgcctgattc atcttgtcgc ggtcgagccg tccttccttg tcacccaaca gcgacagcgc
     6121 gacctggaca gtgtaggtcg ctctcgggtc ggcgcctccc ggtttcggcg ggcaggacgc
     6181 gagacacggc acatgctgcc ggatgtaggc gctcagcgtt tggtcgagaa ctcggtaata
     6241 ggaatcgtcg cccttcgccg ccgcgtccac cgcgagattg cgaagcccgt acattccgcc
     6301 gacctgttcg gcctgctcac tcgaacttat ctgaccgatc gtcttcacca gccggtcact
     6361 gctctgcgtt tcctggttga ccgtcaactg gtctttcgtc gcgcgccatt ccaggaaggt
     6421 gaacgcgaca ccgataataa gcacgaccgc gccgattatc tcgaggttgg tcttccgcag
     6481 ttcgttctcg acgctcagcc ggtccctcgg cgccaggtcc ggggcctgcc ggtccagctt
     6541 cgtcttgggc gctcggccgg cccagcgaac ggccacgacg aggagcgcta cgccaatcag
     6601 gagaatgacg aggtcgaccg cactggcgtc acgaaacgga ccggtcagca cttcaacccc
     6661 ttcttcacct gatcgacgac gtattccagg gcttccggat attttcgctc actctcgccc
     6721 ggcttcggct ccggaggact ttccagcgag gaaagatatt cgaagatcgc accgaactgg
     6781 tcggcgagtt cgtcgatttc ctttcgttcc gcgtccgggt ttttcccctg cggccccttg
     6841 gagtgttcca ggaacagggt ccggtgacct tcggtctgcc acaatgtccg caacaacgca
     6901 cgccgctcct cggcctgggc cgacggcagc gtcttggacg aaattctggt caccgggagt
     6961 tgtttcaatt cgagccattc cacgagatag gcgtatgccg gatgctcggg gacgatcgtc
     7021 ttgttccggc aacccgccgc cttcagcttc aggcggtcac ggatctcgac cagcttggtg
     7081 gtggcctggc ccaggcgctg gttgatgccg tcggtgtgcc tggcgcgcgc gtcggccaac
     7141 tcgggccgct gctccaccgc tttcaccaga gaacgcgcca ccttgcgagc gacggtgacc
     7201 attcgcccgg ccggatccag ccatacgtgc gggtcccggt tgcccggaag ccgatcgtca
     7261 cccaactccg gcggcgcggt cagcagcgcg atgttgtcca gcgcgctgat gtcctggaat
     7321 cgctccggat cggccttggc ccgcgcaccg agggcagtcg cggcctcggc ggacaggttg
     7381 ccgatgtaga gcaccgaatc ggcggtccgc atctggtcga tgtcaccctg cgccggcggc
     7441 tcgtgcggct tgctctcgaa caccttgacc tcgccgacca gctccccgcc gatctgttcg
     7501 accagccagc ccagtgccca cacgttgacc atcacggtga gcttgggcgt tggcgtggcc
     7561 gacggggatg gctccggcgg cgtgctggac cagctacaac tggtgagcga taagactgcc
     7621 gcgagaatcg cgccgactgc gatcgatctg cgcatgaatt gcccccaggc aactactggt
     7681 gatggttatc accatcgtta agcccgagcg taccgccact gtgcgcgaaa caccacgatc
     7741 cggtcagagc cacgcaccga gagtcaactc atcgcccgct gaccgcgcga gtcccaccct
     7801 cggcaccctg agtcgcaccc tcgtggtgcg gctcggcctg cttgagcatg tcgcggaaga
     7861 tcacccagcg catgaccgag tacatgtaga ccgcctcgca ggagccggcc agcagccgcg
     7921 cgagcagata gtgcacgccg agtgaggtca gcccggcgcc gacgccgagg atgaacgcca
     7981 ggtagttgat caacacggcc accgcgtaca gcagggcctg cgggccgacc ggcgcgtgcg
     8041 agtggaagtt gaacgtgcgg ttgaggtagt acgccagccc gaacgcgatc acgtagccga
     8101 tcgtgaacgc gatgcccgac ggccagccga ggccgacctt catcaggctg agcaacccga
     8161 tgtccacgct gaaggtgaac ccgttgatga tcgcgaagcc gagcaggctc ggcgggacga
     8221 tgcggctcag tccgaacggc aggcggcgga tcaccgcagc gcagaagtcg gagaaccggt
     8281 cggtgatggg cctgcgttcc cccgtcgtgt cgtgcacgga atcagcgttc cagtccgagg
     8341 tgaaccagtg ctgaacggcg tgcagagcgc gggactcgcc gatgcggggc gcgggactcg
     8401 cgggtgcagg gcgcgggact cgccggtgca cagcgcggga ctcgcgaggg tcaggtggcg
     8461 cgccagcagc cggcgatgtg atcgtcgacc atgccggtgg cctgcatgag ggcatagcag
     8521 gtggtggggc cgacgaacgc gaaccctcgg cgcttgagct ccttggccat ggcggtcgac
     8581 tccggggtca ccgccggcac gtcgtccatc gaggacggcc gggtccgccc ctcggcgggt
     8641 ggcgcgaacg accagagcag cgtgtccaac ggctcgtcca gctccagcag ggcgcgcgcg
     8701 ttgccgatcg ccgcgtcgat cttgcgacgg ttgcgcacga tcgcggtgtc ggccatcagc
     8761 cgtgccacgt cgtcgtcgcc gaacttcgcc acggcggcgg gatcgaagtc ggcgaacgcc
     8821 cgccggaacc cgtcgcgctt gcgcaggatc gtcagccagg acagcccgga ctggaacgcc
     8881 tcgaggcaca accgctcgaa cagcgcggcg tcgccgtgca gcggcacacc ccactcggtg
     8941 tcgtggtacg cggcgtagtc cggcgtcgag ccgccccacg agcaccgtgc ccggccgtct
     9001 tccccgacga ccgccgaacc atctgtcacc gaggcgcctc gtggtcggtt tcggccacct
     9061 gctcctccag ctcggcgacc ctggcgcgca gtgagtccag ctcgccgccg agccgctgca
     9121 gcacccagtc cacctcggac atcttgtagc cgcgcaccac gagctggaag cgcaggtcgc
     9181 gcagatcctc gccggtgacg ccggacgcgg gcagcctggt cggcgacgcg ccgggtggca
     9241 gcggcggcag ctcctcgccc cggccgaaca ccaccgaggc gagcacgaac accacggccg
     9301 ccacgaggat catgacgacc aggtagatca gcgctgtggt cacgccacga tggtggcacg
     9361 acaccccgtg aaggtggcgt tcaccccgcc ttcacgcgtt acggtcacgt tcctgccatg
     9421 gtgtccgtcc tgttgctgac aacgccggtt cttccctacg tccgccggat tgcggaaagt
     9481 tatcccgccc ggtacgggcg ccaggagcga tcatttgggg agatcatgag aaacctgacc
     9541 agccgcgtcg ccgccgtctt cctcgccgtg gcggcgacgt tcagcatcgg aacgaccgca
     9601 ctcgccaccc cggcgactcc accgtcggcg ttatcgccga tcccgtcgga cggcgacccc
     9661 agcgagtgtc cgccgccccc gggaggcccg gtgccgcagt cactccccca gtcggccggc
     9721 gacgaaccgg gccagggcga gccaggccaa ggcgaccccg gcgaggacga ccaatgcgga
     9781 gcattcgcct ggggctgacc gcctgcgatt aagaccctga aagggtgctc gatcggtttc
     9841 gaaccgatcg agcacccttt ttctttgccc gatcccgtgt cacgttcctg ccatcgcgtc
     9901 cgtcctgttg ctgcccgaca aatccctttc cgcgagcccg ccgttcgccg agcattgttc
     9961 gcgacgggac aacgaccggt aagccaggga gtgatcgacc atggatcaaa tgctttccct
    10021 gtactgcgtc gcggacgaat cgttcttcga ccggcccgac cgaatggacg acggcgccac
    10081 caggttcgcc gtggccgatc gcccggctcc gaccaactgg ggccggggcg agtcggacct
    10141 ctgggtcggc ctcgcgtcgc cccacggccg cccaccggct cagggctgga agatccacgt
    10201 ctcggtgacc agggaagacg cggagcgctg cctggacatc gtgtgggact actgcgccgc
    10261 gaacgatctc gacttcaagt tcctgcgcag cgccgacgcg atgctgatcc tcaacgccaa
    10321 gtacgcgcgg cgcgggtcca gcggaaagct cgtcacgctg tatccccgtg acgacgccca
    10381 gctcgcacac gcgttgaccg aactcgacgc gcgactctcc ggcctttccg gcccttacgt
    10441 tctcggcgat ctgcgcatcg gaaagggacc gctctacgtc cgttacggcg ctttcgacga
    10501 aatgtggtgt cacgacggcg gagacgatcc ggcactggcc atcgccgacc cgcgcgggga
    10561 attgattccg gaccggcgcg agcccgtgtt caccgtcccg gaatgggcgg cgatcccgga
    10621 cgtactgcgt ccccatatcg aggcgcggac gaaagcgagc gcggcggatt tcccttaccg
    10681 cgtgaccgag gcgctgcact tctccaacgg cggcggcgtc tacgtcggcg aggactcgtc
    10741 cggcacgaag gtggtgctcc gggaggcccg gccgcacgcg ggcctggacc gtcacggcac
    10801 cgacgcggtc cagcggctgc gccgtgagca cgacacgctg gcccggctgt ccggcctgga
    10861 ctgtgttccc catgtgctcg accaccgggt ggtgcaggac caccacttcc tggtcgagga
    10921 gttcatcgag ggcaccacgc tgctgcgggc gatccagacg cgcagcccct cgctggcgcc
    10981 cggcgcgtcc agcgaggaga tcaccggaca gatccgcgac taccgcgact gggccgtgga
    11041 cgttctcgag cgaatctcga ccgcactgcg cgccgtccat tcgcgcggcg tccggttcgg
    11101 tgacctgcac cccgcgaaca tcctgatcca gcccgacggc gaggtcgtgt tcgtcgactt
    11161 cgagttcgcc gccgacctca ccgacgacgt cccgcccgga ctcggcgcgc cgggattcat
    11221 cgcaccacca gggctgaccg gcgccgaggt ggacctctac gcgctgaact gcctgcgggt
    11281 ctacctgttc acgatgttga cgccgctgac cgacctggac cgggccaagg cggtcacgct
    11341 ggccgccgag gcgtgccggg acaacgcgat gccgaccgag ttcgccgacc ggttcgtcgc
    11401 ggccacgcac ccggccggcg ccacgccggc acctgatcgc gccgccgacc tgttcgccga
    11461 cccgtcctgg ccgacgatca gggactcgct ggtcgccggc attctggaca gcgcgacgcc
    11521 ggaccggacc gatcggctgt tccccggcag cccgcagcag ttccgcaccg gcggcttcga
    11581 cctcgcccac ggtgccgccg gcgtgctgct cgcgctgcac cgcgtgggcg ccccggtggc
    11641 cgacgagcac gtcggctgga tggtgcgcgc cgtgcaggac gcaccgacgc gcccggcact
    11701 gggtctgtac aacgggccgc acggcgtggc cgcggtgctc gacgagctgg gccggcgcga
    11761 cgaggcgctc gatgtgctgg acgtggcgcg cgccttcgac cgtctgccgg cgtcggacac
    11821 gctctacggc gggcacgccg gccgggccgt caacctgctg cacttcgccc gcgccaccgg
    11881 tgaccaggag ttgcgggccg ccgcgctgga actcggccac gacgtcgccg cacgcgcggc
    11941 gagcgggacc tggccgaccg gtcgcggcct gctgcgcgga ccgtccggag tggcgctgct
    12001 gttgctgcac ctgcacgagg agaccggcga cgcccgctat ctcgatctcg cctggcaggg
    12061 cctgcggcgc gatctggaca acggcgagac gctccccgac gggaccttcc agttgcgcgc
    12121 cgagcaccgg gcggtgccgt atctcgacgg cggcggcagc ggtgtcgcgc tcgtactgca
    12181 cgagttcacc cggcaccacc gggacgccga aaccgaccgg atcatggccg gcatccgccg
    12241 agggtgcgcc gtgccgttcg tctacctgcc cgggttgttc tccgggcgcg ccggcttcgt
    12301 ggcgacgctg gcgcggctcg gcaccgaccg tgacgtgctg cgcgaacacg tgcaccgctt
    12361 cggctcacat gcgttgtcgc gcaacggaaa cctggtcttc ccaggtgatc agttgctgcg
    12421 gctgtccctg gatctggcga ccggctcggc gggcattctg ctcgccctgc acgcggtctt
    12481 cgacggtacg cgcgcggtgc tgccgtacct cgagacccgg tcgccgacgc ccgtccgcac
    12541 ccgtgaagga ggtgaacaac atgaccaaca tcctcgacct gcagggcctt gaggtggacg
    12601 gtctggcctt cggggccgag acctgcccga gcagcaagtc cgtcgtcatc atcgtcaccc
    12661 agcgctgacc gccttggtga cgcggtggtt cgccgccttc gcccgcggac gcggcgaacc
    12721 accgcacgat ccggattacg gagacaccca tgggcgagac gatcacggcg gttccgctgc
    12781 gccgcaatcg cgacttccac ctgatctggg tgggcggcac gctggccggc ctcggctcgc
    12841 ggatggccgc actcgccctg ccgctacttg tgttgcagca gaccggttcc acggccaagg
    12901 cgggtctggt cggctcgatc tcggccgcca cgttgttgat cgcgatcatc ccggccggcg
    12961 cggtggccga cgcggtcgaa cggcaccggc tcatgcggta ctgcgaactc gccgggtcgc
    13021 tgatcgcggc cgcgctcgcc gcgacggtgc tcgccgggtc gcccgccatg ccggcggtgg
    13081 tgatcaccag cgtcgccgtg gcgatcctcg gcagcctcta cgccccggcc gccatcgggt
    13141 tgctgcgtgc ggcggtgccg gccgaccaac tcggcctcgc gatgtcccgg ctgcaggcca
    13201 ggaacgccgc gacacagatc gccgggccgc tggccggcgg cgcgctgttc ggggtggcac
    13261 ccgcgctgcc gttcgccgtg caggcgggcg cgatgttcgt gtccttcggc tgcctgctca
    13321 cgatccgaac ccggtcgagg ccggcgccgg acgccacccg cctgactccg cgccagatca
    13381 ccgccggctt ccgattcctg tggcagcagc ggtatctgcg cacgatcctg atcgtctacg
    13441 gcgcggggat gaacgccacg ttcagcgcgc tcatgctggt cacgatcacg gccagcgcgc
    13501 acgccgaccc gagcggacgg tccagcggcc tgatcgtcgc cctcgcttcg atcggttcgt
    13561 tggccggcgc cctcgccgcg cctcggctgc gctcggccga cgcgccgcac acggtgctga
    13621 cgctgacctc gtggtgcatc ggggcggcca cgctgttgtt cgtcgtggtc acccagccgc
    13681 tcgcgcaggg cctgctgctc gccgtcgtgc tgtttctgtc cggcgtcgcg aacgtcgcgt
    13741 tcgagaccga gcaggccagg ctcacgccaa ccgacctcgc cggccgggtc gaggccgcgg
    13801 ccatcttcat ctcgatgatc gcccagcccc tcggtccact cggcggcggt ctcctcgccg
    13861 aggcgtacgg cccggcgacc gcattcctcg tcatcggcgc gctgatcgcg atcgtggcgg
    13921 gctttctcac cttgtcgttc aggcgaatca attccgacac aacaggaagg caatgaaatg
    13981 ggaagaacag ttcggtggct cggtgccgtg gccgcggccg gcacggtggc gctgtccgga
    14041 gcgggcgtgg ccgcggcgac gccggcaccc gcggtttccg gctactacac gggattcggc
    14101 tccggttcgt cacagcagct cgcactctgg tcggcgcagg atcaggcgta ctggaaggcc
    14161 agtattggcg ggtttcgccg gttcgactgc cgcgtgacct attcgaacgt caccggtggc
    14221 ccgtattcgt attcggcgta tgtgaacctc tactgctggc ggccgtgaat cgtcagatcc
    14281 aaccgcggcg agtggcctcg acgccggctt cgaatcggct gccggcgtcg aggcgctcca
    14341 tcagcttcgc cactcgccgc cgcaggtgcc gcaccgagat gcccgccgcc ctggccgccg
    14401 tctcgtcggt actcccggac gccagcagcg ccagcacctg gcggtcctcg tcggtcggga
    14461 cgaacgcccg ctcgtcctcc tcgtccgccc acggcaacgg ccgcgcggcg tcccacagtt
    14521 ggtcgaacag ccgcatgaaa cccatgacca ggcccggctg ccgcacgatc tggccgccga
    14581 ggtggctgcg atcgggatcg atcggcacca cgacgacccg cttgtccatg atgatcatcc
    14641 ggtccagcga gtcgtcggtg atccgcacgg ccgcaccggc ggccacgatg tcgcgcaggt
    14701 agtcgcggca gtactggtcg gcgaggaacg tcgtgttgta gatgatccgc atgtcgacgc
    14761 cgcgccgcag cgcccgcagg tccagcggcc tgctcgcgtt gagcatctcc tcgctgagcg
    14821 ccccgcccgg ctggaccgcg tacacggtcg acctggtgaa gaaggccagc tcctcgagcc
    14881 gctcccgcaa cacctcgagg tcggtgacgc gttcgatgcc gctgtccgga tcggcgacca
    14941 ggccggcccg tccggcgaac cgcatgccca gctcggcgac ctcggcccgg gtgtcgccga
    15001 cgcggcggtg catccgcagc agctcgtcct cacgccgctc gatcaggtcg ccgagcgcgg
    15061 acaccggatg tgccagcgcc acgccgaggt caccgtccct ggccaccttc gccacgccga
    15121 gttcgaccag gccgtccagg atctcgcgag ccgtgttccg accgcagccg atcaggccgg
    15181 cgacgtcggc cagcgacatc gtcggatcgt cgaccagcgc gcggtaggcc agctcctgct
    15241 gtttggtgaa ccccagatcc gtcagcgcca cggcatcacc cccaggctcc ggacaacccg
    15301 cacagcatgt ccggccgccg gggcgttgtc gagcgtcgcc gcgatcggcc ggccccgccc
    15361 cacgccccga tgtccgaaac ttagcgatcg ctccattcat gttcggcgta ctttagcccg
    15421 ctaaagtccc ttggccgcag caaaggcgca ggtcagccac aggtcgggcg acgcgaaata
    15481 cgtgaagggt gttgcgaata tgggcgcgtc catctcgccg agggcgacgt ccggtgatca
    15541 caccaggcac agtgacagcg agcgcctcgc cagcaggacc agccgcaccg cgacgaccag
    15601 tgcggtgagg ctcgccagca gcagtgggaa gggcgtcacc gtgacgccga acccgaacgc
    15661 ggccgagccg gcgaccatgg ccagcagcgc ggccaggtgc acggtcgcgg cgagcatggc
    15721 gatgatcccg ccgtgccggc ccactcgcca cggttcgacc gaggtgcgcg tcatgtaccg
    15781 ggacgcgatc agcccgagca gcgccagccc ggtgatcatc cacaccgcca cgtcgttgaa
    15841 ccgcgcgatc accaggaacc agtccggcgc cgtccagttc atgttggacc acgagccgag
    15901 ccagagctgg cggttcagct cccagaacag gttcatcgcg agcggcacca gcaacacggt
    15961 gcgcagcgtg cgcaggctgt gcgccacgcc cagctcggcc tggtactccc tggcgatctg
    16021 gtccaccggc ccgaagtcgg cgaccgcgag ccgccgcgcc tcggcctcgg gtttgccgga
    16081 ggaggcgtac gcctcggccg cgtcgaccag tccgtcgcgc gcctcggtga gcaggtcggc
    16141 cttgatcgac gccggcccgc gcagccgccc gtccaactcg gcgagatagt cgtcgatgtc
    16201 gtgcccggtc atgcccctgt tcacgcccct gcttatgtcg gggacggcca tggcccacct
    16261 ccgagaacgc cgtcgatcgc cgtggtgaac tcccgccacg cggtgcgttc cttggcgagc
    16321 gagcgctcac cggtcgcggt gagccggtag gtgcggcgct tgcggccgcc gaccgtgctc
    16381 cactcgctgg ccacgtatcc cgcgcgttcg agccggcgca gcgccgggta cacggtgccg
    16441 gtcggcaggt cgagcgcgcc gccgctgcgc agctgcagcg cctcgatgat cgcgtagccg
    16501 tgcagcttgc cgccgtccag cgtggcgagc aggagcgcgt cgagatggcc gcgcagcgca
    16561 tccgccttca tgagtagcca ccctacttgt cctggactcg cgagtcgtcc gtgacgcccc
    16621 tgatttccga tctcagggtt gtccctgatt gcgttccgcc gctacatgta ggttagctac
    16681 ctatcgccgt acaacgcatc aagcaaaggc cacaccatga gtgacgccgt tgatctcgcg
    16741 cgaatccagt tcgccacgac cacctcgttc cacttcctgt tcgtgatgct gacgctcgga
    16801 ctggtcaccc tggtcgcgat cacgcagacg cgatacacgt tgtccggcaa cgagaacagg
    16861 cgggaaactc tcagcaggat gacccgcttc tggggccacc tgtacgtgat caactacgcg
    16921 ctcggcatcg cgaccgggat cgtcatggag ttccagttcg gcatgaactg gagtgggctg
    16981 gccaccgtgg tcggcgacgt gttcggcgcg ccgctggcca tcgagacgct ggtggcgttc
    17041 ttcctcgagt cgacgttcct cgggctgtgg atcttcggct ggggccggct gaacaagtgg
    17101 ctgcacctgg cgctgatctg gctcaccgcg ctcaccgcgt acgcctccgc gttctggatc
    17161 atggtggcca acgcgttcat gcagaacccg gtcggctacg aagtcatcgg cgacggcggc
    17221 gacgccacag tgcggctgac cgacttcggc gcgctgctgt ccaacccgat gttcggcgac
    17281 gcgctgctgc acgtggtcgc cggcgcgctg gtgaccggtg gggtgttcat ggccggcatc
    17341 agcgcgctgc acttcctgcg gcgcaccacc gaagtcgagt tcttccagcg ctcactgcgc
    17401 ctcggtctgg tgaccgcggc gatcgccgcg ccggtgctga tcggcttcgg cttcgcgcag
    17461 ttctccacga tcgacgaact ccagcccggc aaggtgagcg agggcggcga tgccgcggcc
    17521 gccgcgcagg ccgaactggt cgcgaggtac ggccccggtg actacatcac gcccgagtgg
    17581 gcgaacgggc tgttcggcca gatgatcgag ttcggcttcc tgctcaccct ggccctgttc
    17641 gcgatggtgc tgatgctgtt ccggggatgg ctgttccgcc gccggctgcc gttgcggctg
    17701 ctggtggtca tgatcccgat cccgttcgtc gcggcgatct ccggctggtt gttccgcgag
    17761 gtcggccgcc agccgtggct ggtgtacggg ctgctgcgca ccgaggacgc ggcgagccac
    17821 gtctcggtcg ggtcgatgtg ggtgtccctc gtcgtgttca cggcgctgtt cgcggcgctc
    17881 gcggtcgccg actgggtgct gatcgcccgg gtcgcccgcc gggggcccgc gccggccgag
    17941 gcagcactgc caccacgtcc cgtcacacct gaacccgttg cgctgtaagg ggattgcaca
    18001 tggacacgct gttgctggtc gtcatcgcga tgctgttcgc cgggtacttc gcgctcgccg
    18061 gattcgacta cgggaccggg ttgctctacc gcacgctggg caccgacgag ccggagcggc
    18121 ggcgggtgct cggcacggtc ggcccgttct tcctcggcaa cgaggtgtgg ctggtcgccg
    18181 cgatcgggct gatgatcggc gcgttcccgc gctgggaggg cgaactgctc tccggcgcgt
    18241 acccgatcgt tgtggcgatc ctcgtcgggt tgatcacctt caccgccgcg ttccaactgc
    18301 gtagccgccg cgacggtgcg cggcgtcgcg tctgggacac gctggtgacc ggcggcgcgg
    18361 cggtgaccgt cgccggctgg gggctgctgc tgggcaacct ggtgcgcggc ctgccgctgg
    18421 agaacggccg gccggcgggt gacgtgttgg acctgttctc gccgtacgcg atcacctggg
    18481 gcgtcgggtt cgtggcgctg ttcgggctgc acggcgcggc cttcatcgcg atgcgcacgg
    18541 cgggcaagct ggccgaacga gcccgccgcg ccggccgcgc gtgcgccggg cccgcggtgc
    18601 tgttcgtggt ggccgccggg gtgggcggca tgctgtccga cgaggtcggc gctgccgtga
    18661 cgcggccgtg gctggcgatc ggcggcgccg ccgtgttcgc cgcgctgctg atgacggcga
    18721 gttcgtcact cgcccggtat cggccccgga tcgcgttcgc ctgcaccacg acggtgtgcg
    18781 cgctgctgat gccgctgctg ctggccgccc gctacccgaa cctgctgacg tccacagtgg
    18841 actcgaaggt gctcaccgtc gagcagggcg tggccggcgg ggcgacgctg gacgtgctcg
    18901 gctgggtcgc gctggcggtg atcccgctgg tgttgctgct gcagtggacg gtgtggtggg
    18961 gcaaccgccg caaggtcgat gagcgcacgc cgctgttctg gtaggccgcc gtgatcgaca
    19021 aggtgctgtt gcacgagttc ccgcggttgc ggcgctacct cggcacactc gcgatcttcg
    19081 cgagcctcac ggcggtgctg gtgctggcgc aggccgaggt gctggcccgg ctgctgtccg
    19141 gcggtgcttc ctggacgctg ttcgcgctcg ccgccgcggt gctcgccgtg cgcgcgatct
    19201 ccttgtggtg gcagggaaat ctcgcctcgc gggtggccgc cagggtgcag gcggacgtgc
    19261 gctcacgggt gctgcgatcg gccgcggctc cgggcggcgc gccgtccggc gaggtgtcca
    19321 cgctggtcac ccgaggtgtg gacgcgatcg agccgtacgt cgccggctac ctgccgaccg
    19381 tgctggtgtc ggtcaccgtg ccgctggcgg tcgtggcgcg gctgttcttc gtggactggc
    19441 cgtccgcgtt gatcatcgcc ctgacgctgc cgctggtgcc actgttcgcc gcgctggtcg
    19501 gcgcgcacac ccggcggcgc accgagcggc agtacgcgct gctgtcccgg ctgggcggtc
    19561 acttcctcga cgtggcacgg ggtttgcgca cgctgatgct gcacggccgg gcgcgggcac
    19621 agtcggacac ggtgcgccgg atggccggcg aacacgcctc ggcgaccatg ggcacgctgc
    19681 gggtggcgtt cctgtccgcg ctggtgctcg aactggtggc gacgctgtcg gtggcactgg
    19741 tggcggtgcc ggtcgggctg cggctgctga ccggcggcgt gacgctgctg acggcgctgt
    19801 tggtgctgct gctcgcgccg gaggcgtacc tgccgctgcg cgcggccggc gcccggttcc
    19861 acgcgagcgc cgaagggctg gccgtgctgc gccgcgcgat cgacctggag ccgatctcgg
    19921 tgccgcacaa gggaaagcgc gtcgacgccc gaacggcggt cattcgcttc gagaaggtga
    19981 ccgttcgcta cccctcgcgc cccgagcctg ccctgaacgg ggtgagcctg accgtgcgcc
    20041 ccggcgaacg cgtggtgctg gtcgggccga gcggcgccgg caagagcacg ctgatcggtc
    20101 tgctgctcgg gctggtcgaa ccggacgagg gtcaggtcac ggtggacggt gtcgacctgc
    20161 gcgacatcga cctggactgg tggcgcaccc aactgtcctg ggtgccgcag cggccgtggc
    20221 tgttcgccgg gtcgctggcc gacaacgtgc ggctgtcccg cccggacgcg accgacgacg
    20281 aggtgcgcgc cgccgcccac gcggccgggc tcgaccgcgt gttcgccgca cggggagaca
    20341 gcgcgctgga cgagcgcggc agcgggttgt ccagcgggga acgccagcgg gtggcactgg
    20401 ccagggcact gttgcggacc gactcgccga tcgcgctgct ggacgagccg accgccaggc
    20461 tggatgtgcg caccgagcac gcggtgctgt ccgggtggcg caggctcacc gccggccgga
    20521 cctcgatcgc cgtggcgcac cggccggccc tgctcgccgg ggcgcatcga gtggtgcggg
    20581 tgcacgaggg gcggaccgca tgagtccact gtggacagtg ttcggcgcgc gccgggccgc
    20641 gctgctgggc gccgggctca cctcggccgc cgccgaactt gccggcgtga cactcaccgc
    20701 gaccgccgcg tggctgatcg ccagggccgc cgagatgccg ccgatcggcg cgctgaccgt
    20761 ggcgatcgtg gcggtgcgca cgctggcgat cggccgcggc gggctgcgct acgccgagcg
    20821 gctcgccggg cactccgccg tgctgcgctg tgtcggcgag ctgcgcggac gggtgtacga
    20881 cacgctgctg gcccggcgga cggcggcgcg cgacgccgac ctgctcaccc gcgtggtgtc
    20941 cgatgtggac gcgacgcagg acgcggtgct gcggtgcgcg atcccgatgg cggtcgggct
    21001 caccgtgacg ctgacggcgg gtgtcgcggc cgccttcgcc gatccgctcg tcgcggccgt
    21061 cgtgctcgcc ggactggtgc tgacctgcgt cgtgctgccg gccggttcgc tcgcgctggc
    21121 ccggcggacg gcggcggcca ccgcaccggg acgggccagg ctggccgagc agaccgcgga
    21181 cctggtgcac ggcgcggccg agctgaccgt gttcggtgcg gtgccggatc ggctgcgcga
    21241 cgcggacacg acggtgcgcc ggctggcccg atcgcagcgc ggcacggcgg cggtcacggc
    21301 cgtgctcgga gcgggcgccg tcgtggtcca ggcggtgacc tgcctggccg tgatcatgct
    21361 cggcatcgct cgcgacctgc ccggaccggt ggtggcggcg atcgccctcg gcgcgctcgc
    21421 ggccatcgag accacgatcc cgctggccgg ggcggcggcg cgctgggcgg aggtgtcgac
    21481 cagcgtgcga cggctgggcg aactgctgac cgggccgtcc gctgaaccgt ccactgtgga
    21541 gggtgtacgg ctggaggtgc caccgggggc gcgcatcggg gtggtcggtc cgaccggctc
    21601 gggcaagtcc acgctgctcg acgggttggc gcgggagcgg gtcgcctgcg gtgtgctggc
    21661 cgacgcgcac ctgttccaca ccagcgtgcg gcacaacatc gcgatggcga aacccggtgc
    21721 cacacaacag gatctggacc gggtggcggc gctggtgcgg ctggacgagt ggatcgcgtc
    21781 gttgcccgac ggctgggaca cggtgctggg cgagtccggc gcgaccgtct ccggcggcca
    21841 gcggcagcgg ctgctactgg cccgcgcgct gctcgccgcg ccggccgtgc tgttgctgga
    21901 cgagcctgtc gaagggctgg atcacgccat ggccgacgcg gtcctggctg acgtgctcgc
    21961 cgcgagtgac acggtcgtgc tggtgacgca tcggctcgcc ccgctggcgc acgggttcga
    22021 cgagatcgtg gtgctcgacg gcgggcggat cgcgcagcat ggcacgcacg aggagttgct
    22081 cgcccgcgac gggtactacc ggcaggcgtg gctcgccgag cggatgctcg aatccggttg
    22141 cggcacaaac gatccgtcgc gcaccctgtc ggcgtgaaca tcgtcgcgat cactgaggac
    22201 gactgggccg cgctgcggga gatccggctg gccgcgctgg ccgacgcacc gcgcgccttc
    22261 gggtccactg tggacagaga acgcgcgttc ggtgaggagc gctggcgtga gtggacccgc
    22321 cgcgcccagg tgttcctcgg tgtcgtggac ggcgtgccga aggcgatcgc cgccggcatg
    22381 ctcgaggcgg gcgaggtgca gctgatctcc gtctgggcgg cgccgggcgc gcgtggcacc
    22441 gggctcgcat ccgccacgat cagcgcggtg atcgactggg cgtgcgccga gggtcacccg
    22501 cgcgtgcgca cctgggtggt cgaggacaac ccgacggccg cgcggctcta cgagcgcctc
    22561 ggcttccaga ccaccggcac ccgcatgccg ta
//
