LOCUS       NZ_RYEV01000007        10828 bp    DNA     linear   CON 10-DEC-2024
DEFINITION  Peristeroidobacter soli strain JW-3 Scaffold6_1, whole genome
            shotgun sequence.
ACCESSION   NZ_RYEV01000007
VERSION     NZ_RYEV01000007.1
KEYWORDS    WGS; RefSeq.
SOURCE      Peristeroidobacter soli
  ORGANISM  Peristeroidobacter soli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Steroidobacterales; Steroidobacteraceae; Peristeroidobacter.
REFERENCE   1  (bases 1 to 439371)
  AUTHORS   Huang,J.-W.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-DEC-2018) College of Life Sciences, Nanjing
            Agricultural University, No. 1, Weigang Road, Xuanwu District,
            Nanjing, Jiangsu 210095, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: SOAPdenovo v. 2.04 September-2018
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 174.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004138485.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 18:33:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,689
            CDSs (total)                      :: 7,636
            Genes (coding)                    :: 7,552
            CDSs (with protein)               :: 7,552
            Genes (RNA)                       :: 53
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 19 of 84
            Pseudo Genes (incomplete)         :: 74 of 84
            Pseudo Genes (internal stop)      :: 2 of 84
            Pseudo Genes (multiple problems)  :: 11 of 84
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:27:02
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 308786
            Orig. end                         :: 319614
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            RYEV01000007.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..10828
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..10828
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10828
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:5828](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5828
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     misc_feature    204..217
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: strong, score: 22.84"
                     /tool="antismash"
     gene            complement(1274..2218)
                     /locus_tag="EKO19_RS30690"
     CDS             complement(1274..2218)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKO19_RS30690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="caspase family protein"
                     /protein_id="WP_129781230.1"
                     /transl_table=11
                     /translation="MAAPIALGATVNEARFISALLATACALPASAATYTFVVAGLGGEP
                     AYEQKFREQAAAVAGAAETAAGSTNNVIALSGDAARADAVRREFKTLASRMNANDSVVI
                     VLIGHGSFDGENYRFNLPGPDLTDTDLARLFDELPARDQLIINATSASGAVIERWRKPK
                     RVVITATKSGGEKTATRFAQYWAEAVASDAADTNKDQIVTAAEAYAFANGKVEAAFKAE
                     TSMATEHARMEGDNSARFTIARLGTAALAPDNPEVAALLTQRGTIEQDLNRVKEQKASL
                     PDTQYYDQLEEVLVRLALLQREIDAKVGGGATP"
     gene            complement(2185..4461)
                     /locus_tag="EKO19_RS30695"
     CDS             complement(2185..4461)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKO19_RS30695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_129781231.1"
                     /transl_table=11
                     /translation="MPLRRRIHYYWTVFERLFTHPLWAYRTGTFAFASAWPIGLLITSI
                     LVAAALVAWSLWRRRALGWRMVVPVGVLQTLLLALILCLLWRPVLNVERVRDRENELAI
                     AVDASASMAYGDAGTSRLQEVAAALQNGTLQRLEKTFAVRLFGFAQSTTPLNNLEAMPP
                     PGRQTRIGDALHQVLQSAGSAPLAGVILFSDGAENGDTLSEERLAEIASYGVPVHTVGL
                     GPERVADDLELERVAVAGSAPAGSTIDAQIGIRHNGASQARLRVYDRDNLVAARDIKLR
                     PDAATTQLSLDLPAGQAGTHELRFVLDPLAGERNVINNSRTQVVNVPATRRGILYVEGE
                     PRWEYKFLRRAVDHDRALRVASIVRTTTNKHYRQGVNTPDELVDGFPSDPAELFGYDAV
                     IIGSYEAAGLRAEQHRLLKEFVDKRGGTVLMLAGRYGLAAGGWQNAALAQTLPIQLTGK
                     QPSQFVQRPGQAVLTLYGAESSIPRLDIDPRKNLERWKNLPPLADYQALGRLKPGAIVL
                     LEANGEQGRSPLLIWQHYGRGATYVLATASTMRWQMRMPSDDQSHEIFWRQLLHAISAT
                     APARVTLNGERTVYEDERTVRLEAEVHDERFEPISDATVELQVAPERDTPFKQLMQPSG
                     QNDGRYTTTLDAASTGLYRIEMSARSGDKEVGSAVTHVLRNDGVAEHFATYQHRALLER
                     IANVTGGRYWPLRDLAALSQAIPYSKAGIVERQTLDLWNLPIVFLVLLALKLGEWLLRL
                     RWGRL"
     misc_feature    complement(4483..4498)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.86"
                     /tool="antismash"
     gene            4579..5004
                     /locus_tag="EKO19_RS30700"
     CDS             4579..5004
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_function="GO:0004322 - ferroxidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012828934.1"
                     /locus_tag="EKO19_RS30700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="encapsulin-associated ferritin-like protein"
                     /protein_id="WP_129781232.1"
                     /transl_table=11
                     /translation="MSSESLHESAKALQPETIDRHRAVSSLMEELEAVDWYDQRIDAAT
                     DEELKRILAHNRDEEKEHAAMVLEWLRRKDPKLDEHLRTYLFTDKSVLDIEHEAEHGGA
                     DGGTDAGNGCLGIGSLRGEHQNPTREVAKLAGTGIKP"
     gene            5001..5828
                     /locus_tag="EKO19_RS30705"
     CDS             5001..5828
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Linocin_M18"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015257194.1"
                     /locus_tag="EKO19_RS30705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="family 1 encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_129781233.1"
                     /sec_met_domain="Linocin_M18 (E-value: 4.2e-83, bitscore:
                     272.9, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNELLREHAPISSEAWQEIDAEAKRTLKTLLAARRLVDFKGPLGW
                     SCASVSTGRTRTLSPSLQDGVVSKLRLSLPLIEIRIPFEVDREELDAIGRGDTNPDLDS
                     VRNAARAAAIAEDRAIFRGYEAGHIDGIFPAAGAHGLTIPTDYGAYPDVVAEATHRLRS
                     EGVSGPYGIALGPRCYTGLTRSTLRGYPIINHVRELVDGPIVWAPAVDGAVVMSLRGGD
                     FELIVGQDFSVGYLDHTSTSVLLYLQQSFTFRVLSPEAAVPLTYAAVDVTPAK"
     misc_feature    complement(5843..5860)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 17.06"
                     /tool="antismash"
     misc_feature    5994..6007
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.31"
                     /tool="antismash"
     gene            6021..6956
                     /locus_tag="EKO19_RS30710"
     CDS             6021..6956
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1031: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF015431.5"
                     /locus_tag="EKO19_RS30710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LysR substrate-binding domain-containing protein"
                     /protein_id="WP_129781234.1"
                     /transl_table=11
                     /translation="MTTFPVPELPLRRPATMRLPSLKFLKTFQVAAARLSFKAAAEELC
                     ITPSAVSHQIKGLEEQLGVALFERGPSSLTLTEAGESYLQHLETVFARLEAVTEQLRIR
                     YGRDVVRLHIPPFFATEMLLPRLPLFLEVRPDTDVHINTVSGPLQSHPPEADLSIVVGA
                     SPEEAHDHNCHKLFSQSFVPACSPNLLQRVPIDSVQDLNKHTLIIHEARRDGWQRWAQT
                     LGINLRPKSIVRFDSMNTAAEAAEHGVGVALVSTRLGNERFAQGTLVKLFDRELETGES
                     YFLILRKEDAARPNVKALTEWLIEEFSVAA"
     gene            7253..7603
                     /locus_tag="EKO19_RS30715"
     CDS             7253..7603
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKO19_RS30715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_129781235.1"
                     /transl_table=11
                     /translation="MNKLSTRLTKSISLAAATLALAAPFTTQAHNYDAAMDSCINAFVA
                     SSLPKEQPVKIKKEDAVNSPISIHSRAYKIVVSAKGLESGKNIARGTCIVDRSGAVIAL
                     NGKPITQKLAAR"
     misc_feature    7685..7694
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.27"
                     /tool="antismash"
     misc_feature    7685..7699
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.04"
                     /tool="antismash"
     misc_feature    complement(7689..7702)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 17.31"
                     /tool="antismash"
     gene            7834..8298
                     /locus_tag="EKO19_RS30720"
     CDS             7834..8298
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039183.4"
                     /locus_tag="EKO19_RS30720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF5658 family protein"
                     /protein_id="WP_129781236.1"
                     /transl_table=11
                     /translation="MERVPHERRSGVERREHNVAAYWRGALNPRRRAGRRATDRVYTII
                     DWHSPRVLALVLLILGMSSLDGVLTLMLMSQGASEVNPVMALFVPHNLGWFAAIKLTLT
                     SLGVAVLVICARMKLFRLFPGELLLYLVVAGYAVLMGYELHLLANPPLAL"
     gene            complement(8299..8703)
                     /locus_tag="EKO19_RS30725"
     CDS             complement(8299..8703)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKO19_RS30725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_129781237.1"
                     /transl_table=11
                     /translation="MQSRKLHALIAFALFLVAAVVYAALSGKPVDLWRVALWSMVGVGS
                     YTALSHVFGFDPHRTRIAQSSPAYMHYVDRWELRLGQATLSMLGGIVIAARLFDGAHFV
                     TAVVCGTLSAWTYFAFRWYVGGYRAGATSK"
     misc_feature    complement(8762..8777)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.91"
                     /tool="antismash"
     misc_feature    complement(10077..10090)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.21"
                     /tool="antismash"
     misc_feature    complement(10727..10740)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.61"
                     /tool="antismash"
ORIGIN
        1 gtgaacacgt gcgccatctc atgccacagc gtgctgcccc agtggaactc actcgtcgag
       61 cgactcgacg gactgtccat cgcaacgaca tagccgaagg tgacacccag cagcccgatg
      121 ccgggcaatg ccgccacacg cacggcaaag tcgtcatgat ccggatacag ctcgaccgtc
      181 accgtttcgc gcggcttgaa tccgtaacgc tgcgtgaagc tttgaatgct ccggccggtg
      241 agatccaaca catacggccg caggatttcg gactccttct tatgcaggcg cagccggact
      301 tgataagtat ccgggccgat gacgaccgga tcctcgctga tcgagaactc gtcgatgcga
      361 tccagcaggc gcaatgagtt caccgtcgtc gggctgtaag gatcgccgga gtaggcggcc
      421 tgcaaatgcg tacgcgcttc gtcgacgatc ccgagtctga gcagattcga acccagctcg
      481 gcatgcgcgg cccacagatc cggctgcacc tccaccgccc ggcgcaacag cacggtcgct
      541 tccttataac gacgccgcat gatctcgaag tgcgcgagct gctgatacac ggcgccatag
      601 cgcgggttgt agtcgagaat gcgcttgatc cattgatcgg gattgccacc gcgcgacatc
      661 tccaacgacg cgcgcagcgt gtagacctcg agcggcggca gcttgtcctt gttgaccact
      721 cgcatggcgc gatcgagcgc tttctcggcg tcgtcgagct ggccttcctc gagatccatc
      781 gaagcggtga gcagatggcc ttcgaccaga tcgctgtcct gcttcagcgc gtcctcgacc
      841 agcggccgcg cctgcccttc gaagcgctcg gcatagacgc tggccagacc gagcttggca
      901 tgcacgtcgt tgggaaagac cttcagcgct tcgttgaaca ggtcggcggc gtcggaatac
      961 tgatgcgtct gaagaaacaa tcgcgcccag cgcacgcggg gctgcacggc gcgctcattg
     1021 ctttgtacag cgtcacggaa aatctgattg gcacgctgaa tatcaccgag cgcccaggcg
     1081 gcttccgctt cgacgatggg cgtttgcgat tcgagcagct tcgtgtagca agtgcgggct
     1141 tgctcggtac gaccgcgata ccgatgttca tcacaggacc gcagctcgac ggcgcggcgg
     1201 gggtcgtagt cgatcgactg cgcgccagcc gtcgtgccga gtaacagcaa taccaaagtg
     1261 gcagtgcggg tcatcatggc gtcgcgcctc caccaacttt ggcatcgatc tcccgctgca
     1321 gcagcgccag gcgcaccagc acttcttcca gctggtcgta atactgtgta tccggcagcg
     1381 aggctttttg ttccttcacc cggttcaagt cctgctcgat ggtgcctcgt tgggtcagca
     1441 acgccgccac ttccgggttg tccggcgcca gcgcggcggt ccccagccgt gcaatcgtaa
     1501 agcgggcgga gttgtcgccc tccatacgtg cgtgctcggt cgccatcgat gtctccgcct
     1561 tgaaggcggc ttcgactttg ccgttcgcaa acgcatacgc ttcagcggcc gtgacgatct
     1621 gatccttgtt cgtgtccgct gcgtccgacg cgaccgcttc cgcccagtac tgagcaaagc
     1681 gggttgcggt cttttcaccg ccgctcttgg tcgccgtaat caccacgcgt ttcggtttcc
     1741 gccagcgctc gataacggcg ccgctggcgc tggtggcatt gatgatcagt tgatcgcgcg
     1801 cgggcagctc gtcgaacagg cgcgccagat cggtgtcggt gagatcggga ccgggcagat
     1861 tgaatcgata gttctcgccg tcgaagctgc cgtgaccgat gagcacgatc acgaccgagt
     1921 cgtttgcatt catgcgcgag gcgagcgtct tgaattcgcg ccggaccgcg tcggcccggg
     1981 ccgcatcgcc gctcaacgca atgacattgt tggtactgcc ggccgccgtc tcggccgcgc
     2041 cagcgaccgc cgccgcctgc tcgcgaaatt tctgttcgta cgccggctcg ccgcccagac
     2101 cggcaactac aaacgtgtag gtcgcggcgg acgccggcag tgcgcaggcc gtcgcgagca
     2161 aagcggagat gaagcgcgcc tcgttcacag tcgcccccag cgcaatcgga gcagccattc
     2221 acccagcttc agcgccagca acaccaggaa cacgatgggc aggttccaca gatccagcgt
     2281 ctgccgctcg acgatgccgg ccttggaata gggaatggct tgagacaacg cggctagatc
     2341 gcgcaagggc cagtaacgtc cgccggtgac attcgcaata cgttccagca gagcgcgatg
     2401 ctgataagtg gcgaagtgct cggccacgcc gtcgttacgc agcacgtgcg tcacggccga
     2461 cccgacctct ttgtctcctg aacgtgcgct catctcgatg cgatacaggc cggtggaagc
     2521 ggcatcgagg gtcgtggtgt aacggccatc gttctgcccg gagggttgca tgagctgctt
     2581 gaacggcgtg tcgcgttcag gcgccacctg taattcgacc gtggcatcgc tgatgggttc
     2641 gaagcgctcg tcatgcactt ccgcttccag ccgcaccgtg cgctcgtctt catacaccgt
     2701 gcgctcgccg ttcagggtga cgcgagcggg cgcggtcgct gagatggcgt gcaacagctg
     2761 ccgccagaat atttcatgac tctgatcgtc ggacggcatg cgcatctgcc agcgcatcgt
     2821 gctcgccgtc gccaacacat aagtagcgcc gcgcccgtaa tgctgccaga tcagcaaagg
     2881 tgaacggcct tgttcaccgt tcgcttcgag cagcacgatg gcaccgggct tcaagcgccc
     2941 cagcgcctgg taatcggcca gcggcggcag atttttccag cgttccagat tcttgcgcgg
     3001 atcgatgtcg agccggggta tcgacgactc ggcgccatac agggtcagca ccgcctgacc
     3061 cggacgctga acgaattgtg acggttgctt gcccgtgagc tgaatgggca gcgtctgcgc
     3121 caacgcggcg ttctgccagc cgccggccgc caatccatag cggcccgcca gcatcaacac
     3181 cgtgccgccg cgcttgtcga cgaactcttt caacagcctg tgttgctcgg cgcgcagccc
     3241 ggccgcttca taactgccga tgatgaccgc gtcgtaaccg aacaactcgg ccggatcgga
     3301 cggaaagccg tcgaccagct cgtccggcgt gttcacgccc tggcgataat gtttattggt
     3361 cgtggtgcgg acgatgctgg cgactcgcaa cgcgcgatcg tgatcgacgg cccggcgcag
     3421 gaacttatat tcccagcgcg gctcgccttc gacgtacagg atgccgcgtc gggtggcggg
     3481 gacattcacg acctgagtac gcgagttgtt gatcacgtta cgctcgcctg ccaatgggtc
     3541 gagcacgaag cgcagttcat gcgtgccggc ctggccggcg ggcaagtcca acgaaagctg
     3601 agtggtggcg gcgtcgggac gcaacttgat gtcgcgagcg gcgaccagat tgtcacgatc
     3661 gtaaacgcgc agccgggctt gtgacgcacc gttgtgacga atgccgatct gcgcgtcgat
     3721 ggtggaaccg gctggcgccg agcccgccac tgcgacgcgc tcgagctcca gatcgtcggc
     3781 cactcgctca gggccgagac ctacggtatg aacgggcacg ccataggacg cgatctcggc
     3841 gagacgctct tcgctcaagg tgtcgccatt ctccgcgccg tcgctgaaca agataacgcc
     3901 ggcgaggggc gcgctgcctg cactttgtaa cacttgatga agcgcgtcgc cgatgcgcgt
     3961 ctgccggccg ggcggcggca tcgcttcgag attgttcagc ggcgtggtgg actgcgcgaa
     4021 tccaaacagg cgcacggcga aagttttttc cagccgctgc aaggtgccgt tctgtaacgc
     4081 ggccgcgact tcctgaagcc gcgatgtacc ggcatcgccg tacgccatgc tggcggacgc
     4141 gtcgacggcg atggccagtt cgttctcacg atcgcgtacc cgttcgacgt tcaggaccgg
     4201 acgccacaac agacacagga tcagtgccag caacagcgtc tgcagaacac cgaccggcac
     4261 caccatgcgc cagccgagcg cgcgtcgccg ccacagcgac caggccacca gcgcggcggc
     4321 caccagaatc gaagtaatga gcagccctat cggccatgcg ctcgcaaagg cgaacgtgcc
     4381 ggttcgatac gcccaaaggg ggtgagtgaa cagccgctcg aacaccgtcc agtaatagtg
     4441 gatgcgccgc ctcaaaggca agccacaatc ctgctcaaaa tcgtgaagaa gcggtgaggg
     4501 gcagttttcc ttcaggaacc acggacgagt tcatgcgtac tggtttgacg tacccgaacc
     4561 cgagcgcgtt cagccaccat gtctagcgaa tccttgcacg agagcgccaa ggcgctgcag
     4621 cccgagacca tcgaccggca tcgcgccgtg tcctcgttga tggaggaatt ggaggcggtc
     4681 gactggtacg accagcgcat cgacgccgcc accgacgagg agctcaaacg catcctggcg
     4741 cacaaccgcg acgaggaaaa agagcacgcc gccatggtgt tggaatggct gcgtcggaaa
     4801 gatccgaagc tcgacgagca cctgcgcacc tacctgttca ccgacaagtc cgtgctcgat
     4861 atcgagcatg aagccgaaca tggcggcgcc gacggcggaa cggatgcagg caatggctgc
     4921 ctgggcatcg gcagtctgcg gggggaacac cagaatccga ctcgggaagt ggccaagctg
     4981 gcgggcacag gaatcaaacc atgaacgagc tgttgcgcga gcacgccccg atctcctccg
     5041 aggcgtggca agaaatcgac gccgaagcca agcgcaccct gaaaacgttg ttggccgcgc
     5101 gccgtctggt ggatttcaaa ggtccgctgg gctggagctg cgcctcggtc tcgaccggtc
     5161 gcacccggac gttgtcgccg tcgttgcagg atggcgtggt gtcgaagctg cggctgtcgc
     5221 tgccattgat cgaaatccgg attcctttcg aggtggatcg cgaagagctg gacgcgatcg
     5281 gccgcggcga caccaatccc gatctcgatt cagttcgcaa cgcggcccgg gccgcagcga
     5341 tcgccgaaga tcgcgccatc ttccgcggct atgaggccgg acacatcgac ggcatctttc
     5401 ccgccgccgg cgctcatggg ctgacgatcc ccaccgatta cggcgcgtat cccgacgtgg
     5461 tcgccgaagc cacccatcga ttgcgcagtg aaggtgtcag cggtccgtat ggaattgcac
     5521 tcggccctcg ctgttatacc ggcctgactc gcagtacctt gcgcggctat cccatcatca
     5581 atcatgtgcg cgagctggtg gatggcccga tcgtctgggc gccggctgtc gatggcgcgg
     5641 tcgtgatgag tctgcgcggc ggcgacttcg agctgatcgt cgggcaggat ttctcggtgg
     5701 gttatctgga tcacaccagc acctcagtgc tgctgtattt gcagcagagc ttcacgttcc
     5761 gagtactgtc acccgaagcc gccgtgccac tgacttacgc ggcggtggat gtcactcccg
     5821 cgaagtaaat gcgcggctga aattgacgaa ttattaacaa agcgtgacat aagcctttga
     5881 ccgcactgta tttgcgcgcg gtctgatcga gctgccagag cgtggggcgg ccgtcgcgct
     5941 ccacgccggc cgatcacggc cggagcccgc ggaaatcatg ggttctgcgg gacggcacgg
     6001 gacttgctct ccggaaaccc gtgaccacct ttcccgtgcc cgagttgccg cttcgacggc
     6061 ctgcgaccat gcgcctcccc tcgctgaagt tcctgaagac ctttcaagtc gctgccgcgc
     6121 gcctgagctt caaggctgcc gcggaggagc tgtgcattac gccgtccgcg gtcagccacc
     6181 agatcaaggg gctcgaggag caactcggcg tagcactgtt cgagcgcggc ccgagctcgc
     6241 tgacgctgac ggaagccggc gagagttatt tgcagcacct ggagacggtg ttcgcacgac
     6301 tcgaagcggt caccgagcag ttacgcattc gttacggccg cgatgtggtt cgtctgcaca
     6361 tcccgccgtt cttcgcgacc gaaatgttgt tgccacgcct gccgctgttt ctggaagtgc
     6421 gaccggatac ggacgtacat atcaatacgg tgtcggggcc gttgcagtcg catccccccg
     6481 aagcggatct atccatcgtc gtcggcgcct cgccggaaga ggcgcacgac cacaactgtc
     6541 acaaactgtt ctcgcaatcg tttgtaccgg cgtgctcgcc gaatttgtta cagcgcgtgc
     6601 cgatcgattc ggtgcaggat ctgaacaaac atacgttgat cattcacgaa gcgcgccgtg
     6661 acggctggca gcgctgggcg caaacgctcg gcatcaatct gcgaccgaag agcatcgtac
     6721 gtttcgactc catgaataca gcagcggaag ccgccgagca cggcgtcggc gtcgcgctgg
     6781 tttcgacgcg cctcggcaac gaacgcttcg cgcaaggcac tttggtgaag ctgttcgatc
     6841 gcgagctgga aaccggtgag agttattttc tgattctgcg caaggaagat gcggcacggc
     6901 ccaacgtcaa agcactgacg gagtggctga tcgaggaatt cagcgtcgcg gcctgatccc
     6961 gcgcacggct tcttagatgc acccatcggc cgcgccgcag gcgcaggccg atggaatatc
     7021 cagattccca ggggcgagta tttgtttcag ccgcgcttca gcggaggcgg gcgcgcgccc
     7081 atttgtttct attttgtttc cgagtcaggg aatgtctgca tgagcgcgtt tgttgccagc
     7141 atgaaatctt ctcgtttgtc ggcctgactc gcgggctcta gattggcccc attccataaa
     7201 gaaacgttcc aggggattgg agtttttctt ttaacccttt ggagtgatcg tcatgaacaa
     7261 gctcagcacc cgtctcacca agtcgatatc cctggccgcc gccacgctcg cgctcgccgc
     7321 gccgttcacc acccaggctc acaactacga tgccgcgatg gactcgtgca tcaacgcgtt
     7381 cgtcgcctcc agcctgccga aagaacagcc ggtgaagatc aagaaggaag acgccgtgaa
     7441 cagcccgatc agcattcact cgcgtgccta caagatcgtg gtcagcgcca agggcttgga
     7501 aagcggcaag aacattgccc gcggtacctg catcgtcgat cgcagcggcg cggtgatcgc
     7561 gctgaacggc aagcccatca cgcagaagct ggccgctcgt taatcacagc ctgatcactc
     7621 cgggaggcgt gcgcgtctga catccccctg cagtaacgcg ctcgcaagga cgctcctccc
     7681 ggagtgtttt ctgataattt tctcgacaac ctcccctggt cgcgactttc tttcgcgact
     7741 gattacggta acttcagccc atcgcattgc actcttcgcg cacactgacc gggccgaatt
     7801 gtcgagagtc gaggctcctg atccatgcac gcaatggaac gcgtccccca tgaacgtcgc
     7861 agcggtgtag aacgccgtga acacaacgtc gctgcttatt ggcgaggcgc gctgaatccg
     7921 cgtcgccgag cgggacgtcg tgcgaccgat cgcgtctata ccatcatcga ttggcactca
     7981 ccgcgcgtgc tggcgctggt gctgctgatc ctcggcatgt cgtcgctcga tggcgtgctg
     8041 acgttgatgc tgatgtcgca gggggcgagc gaagtgaacc cggtgatggc gctgttcgtg
     8101 cctcacaacc tgggctggtt cgcggcgatc aagctgacgc tcaccagtct aggcgtggcc
     8161 gtgctggtga tttgcgcgcg gatgaagctg ttcaggttgt tcccaggcga gctgttgctg
     8221 tacctggtcg tcgccggtta cgccgtactg atgggctacg agctgcactt gctcgcgaac
     8281 ccaccgctgg cactttgatt atttgctggt ggcgccggcc cgatagccgc cgacatacca
     8341 acggaaggcg aagtaggtcc acgccgagag cgtgccgcaa accaccgccg tcacgaagtg
     8401 cgcgccgtcg aacaggcgcg ccgcgatcac gattccaccg agcatcgaca aggtcgcctg
     8461 ccccaggcgc aactcccaac gatccacata gtgcatgtac gccggcgagg attgggcgat
     8521 acgggtgcga tggggatcga aaccaaacac atgagatagc gcggtatagc tgccgacgcc
     8581 gaccatgctc cacagcgcga cgcgccacag atccacgggc ttgccggaca gcgcggcata
     8641 aacgaccgcg gccaccagaa acaaagcaaa agcgatcagt gcgtgcagct tgcgcgattg
     8701 catgggatga aaccgattga gggaagtgcg gccagatata gcgccatcac tttgccattt
     8761 ctgtgagcgc ggtcaaagcg ccgcgccctg agtctgcggt tgcctctttc cgcaaggcgc
     8821 tcccggtgga ttacctacgt cgcgcatcca gttgcctaca gctatctcac aaccggcgcg
     8881 caaggcaaaa tagcggcctt tggccggacg agaacaacta atgcgattct tccggcgctc
     8941 gctgatcact ctgggggttg ccgcgacgct gcccacagta gtgttcgtcg cggtcggcgc
     9001 tttttatttt ttacgtgcgg agcgggctcg tgtcgaagcc gacacgctcg gccgcagcga
     9061 gatcgcgacc atgctggtcg acggtcgcct gcgccgtgat ctggcggcgc tcggcgtgct
     9121 caccagttcg gtggatctgg ccaagggcaa catgcgggaa ttctattttc gcgtgcagcg
     9181 agtacagacg gccaatcccg cgtggcgcac gatcgttctg atcgatgcac tcagcgggca
     9241 ggaattgttc gatctgcgcc gcccgttcgg cgagcccgcg ccactcagcg aagtgcacgc
     9301 gcaggcactg aaggacatgc gccagaccga aatgcccatg gccgggtcga tttcgccgcc
     9361 gcctgaaaag ctcgcctggg tgtacgcacc cgtcagcggc gaaggtgaat tgcgttacat
     9421 gctcggcgcg ggcatcgagc cgcaggcctt tcaggaactg ctgaaggcag tggccgtggc
     9481 cggcacgacc gcagctgtcg tcgatcggca cggtcagttc gtggcgcgaa ccctcaactt
     9541 cgagacccgc gtcggcacgc cagccaccga gttcgtgcgc aaggccatca aggaaggagc
     9601 cagcggcttc tatccaggca cgacctacga ggggctgaag aactacacgg cgtttcatac
     9661 ctcgccgtgg tcgcaatggt cggcgcacct ggcggtggcg tcgacggcca tcgatgcgcc
     9721 gaccacgtgg tcgttcgttg ccgccgccct ggccgcactg ggggcattga tcctcggcgg
     9781 cacgctggtt ctgctgatgg cgcgagacat ggccgagcgg cgccgtgccg aagaaacatt
     9841 gcgtcagtcc cagaaaatgg aggcggtggg ccagttgacg ggcggcatcg cccacgactt
     9901 caacaatctg ctcacggccg tgatcggcaa tctcgatctg attcgcaatc gggtgaagga
     9961 caacgaacgg ctcagcaggc tcgcggacaa cgcactcgaa gcctcccggc gtggcgccaa
    10021 actcgcatcg caattgctgg cgttctcccg cagccaacgg atggcggtcg gcccggtgga
    10081 tctgcagcaa ctcttcaatg gcatcagcgg cctgctggcg cagtcggtcg gtcccgcgat
    10141 cgaggtgcgc atggaactgg accccgatgc acgcgtggtg atgagcgatt ccaatcagct
    10201 cgagctggcg ctgctcaatc tcgcggtgaa tgcgcgcgac gcgatgcccg gcggcggcaa
    10261 gctgatcatc agcgctcgtc gcgccaacgt cgtcgatcga catctgccga agggcgacta
    10321 tgtgcagctg tcagtgactg acaccggcgt cggcatgact gaagaagtgc gagcacgcgc
    10381 catcgatcca tttttcacca ccaaggcggt gggccacggc accggcctgg gcctgtcgca
    10441 ggtttacgcg gtgactcgcg agtcgggcgg ctccctctac atcgacagcg aaattcacca
    10501 aggcaccacc gtttgtctgg tgctgccgct cgcaccgagc gatgccattg tcgtgccgac
    10561 ggcaataccg gatacagcag caccgtcgga agctgaaccg gagccatcga ccaagagcgc
    10621 tgccgtgctg gtggtcgacg acgacaagct ggtgcggcga ttcatgagcg agtcgttgcg
    10681 ttcgctgggc tacgaggtgc gggacacgga taatggcgtc gatgcgttga tcctgctcga
    10741 cgcccagcgc ttcgatctgc tgctggccga tttcgccatg cccggcatga acggcgcgga
    10801 tctgggcaaa gcggcgcaga tgaaacaa
//
