LOCUS       NZ_RYEV01000005        20834 bp    DNA     linear   CON 10-DEC-2024
DEFINITION  Peristeroidobacter soli strain JW-3 Scaffold4_1, whole genome
            shotgun sequence.
ACCESSION   NZ_RYEV01000005
VERSION     NZ_RYEV01000005.1
KEYWORDS    WGS; RefSeq.
SOURCE      Peristeroidobacter soli
  ORGANISM  Peristeroidobacter soli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Steroidobacterales; Steroidobacteraceae; Peristeroidobacter.
REFERENCE   1  (bases 1 to 1260999)
  AUTHORS   Huang,J.-W.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-DEC-2018) College of Life Sciences, Nanjing
            Agricultural University, No. 1, Weigang Road, Xuanwu District,
            Nanjing, Jiangsu 210095, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: SOAPdenovo v. 2.04 September-2018
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 174.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004138485.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 18:33:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,689
            CDSs (total)                      :: 7,636
            Genes (coding)                    :: 7,552
            CDSs (with protein)               :: 7,552
            Genes (RNA)                       :: 53
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 19 of 84
            Pseudo Genes (incomplete)         :: 74 of 84
            Pseudo Genes (internal stop)      :: 2 of 84
            Pseudo Genes (multiple problems)  :: 11 of 84
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:27:02
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 493885
            Orig. end                         :: 514719
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            RYEV01000005.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20834
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20834
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20834
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10834](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10834)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    29..44
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 21.75"
                     /tool="antismash"
     gene            complement(30..842)
                     /locus_tag="EKO19_RS23720"
     CDS             complement(30..842)
                     /EC_number="5.2.1.8"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024545.5"
                     /locus_tag="EKO19_RS23720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="peptidylprolyl isomerase"
                     /protein_id="WP_129779205.1"
                     /transl_table=11
                     /translation="MNRHLLVGLLLPLTLLAGCGNAAESQKAPAGPPVAVVNGKNISKS
                     EFDLYVENVGRQSKREISEAEKSQLLDQFISMQLAAEAASKAGIEKQPKVQDQLALARL
                     NVLVDSGLQEWLEKNPVTDAELRPEYDAQVAQMPKEYHARHILVDDQAKAEALTKELKG
                     GADFAKLAEKNSKDPSGKNGGDLGWFTLETMVKPFSDAVAALQPGQMTDQPVQSQFGWH
                     IIKLEESRTTQAPAFDEVKDRVKMLVQRKKLQNYLDELRKNAKIEKKT"
     misc_feature    complement(861..875)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 20.33"
                     /tool="antismash"
     gene            complement(881..1150)
                     /locus_tag="EKO19_RS23725"
     CDS             complement(881..1150)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017157809.1"
                     /locus_tag="EKO19_RS23725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="BolA family transcriptional regulator"
                     /protein_id="WP_129779207.1"
                     /transl_table=11
                     /translation="MTRAERIVGELRKALHTEQVELIDDSHLHAGHAGARDGRGHFRVR
                     VVSADFGGLRTLQRHQLVYRSLGDLMQTDIHALSITALTPDEAR"
     gene            complement(1147..1764)
                     /locus_tag="EKO19_RS23730"
     CDS             complement(1147..1764)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR00997.1"
                     /locus_tag="EKO19_RS23730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="septation protein A"
                     /protein_id="WP_407676662.1"
                     /transl_table=11
                     /translation="MIAALSNPPVDRQGPRPLMKLLFDFFPVIAFFLTYKITGNLFVAT
                     GVIIVAVIAQTAWQWFRHRKVSQMALISGVLVLIFGGLTLLIHDKVFIQWKVSVVNWLF
                     AAGFLASRFFGDKLLIERMMGENVQLDPPVWRTLNWAWIVFFTALGIINLYIVYNFSEE
                     VWVNFKLFGMLGLTVVFAIAQAIWLSSKMPPEDTSAPSEKPQ"
     gene            1771..2394
                     /locus_tag="EKO19_RS23735"
     CDS             1771..2394
                     /EC_number="2.7.7.87"
                     /GO_function="GO:0003725 - double-stranded RNA binding
                     [Evidence IEA]"
                     /GO_function="GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA]"
                     /GO_process="GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008171409.1"
                     /locus_tag="EKO19_RS23735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="WP_129779211.1"
                     /transl_table=11
                     /translation="MTSRYLEIHPRDPQLRLIRQAVEIIREGGVVVYPTDSCYALGCHL
                     GDKAAMERIARIRQTDRHHHFTLVCSDLSEIANYARVSNTQYRTLKAFTPGPYTFILQA
                     TKETPRRLQNEKRKTIGVRVPDHPVVTAILDELGEPIMSSTLILPGDEHPLTDPREIQE
                     RLFHFVDAVIDSGNCGLEPSSVIDLAGPAPVVVRRGKGDVSAFE"
     gene            2524..3741
                     /locus_tag="EKO19_RS23740"
     CDS             2524..3741
                     /EC_number="6.1.1.2"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008931657.1"
                     /locus_tag="EKO19_RS23740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tryptophan--tRNA ligase"
                     /protein_id="WP_129779213.1"
                     /transl_table=11
                     /translation="MSSTPATNRRVLSGMRPTGALHLGNYHGALKNWVELQYQYECYFF
                     VADIHALTTGYEDTSQLESNVWNVVIDWLAAGLNPASSTIFIQSRVPEHSELHLLLSMI
                     TPLGWLERVPTYKDQQEQLKDKDLATYGFLGYPLLQSADILLYKTAFVPVGEDQIAHVE
                     ITREVARRFNHVYGREPDFEAKVDKALKALGSRNGTRYNELRRLYQEKGDQEAIAKAHS
                     LLEGTARLTLADRERLIGYLEGTGRSYLVEPEVLLTATPKVPGLDGRKMSKSYGNTIGL
                     REDPDQVAKKLKGMMTDPARQRRTDPGDPDKCPVFDLHKIYSSTETQAWAAQGCRSAGI
                     GCLDCKKPVIDAIVTELRGMQARAKEFEENRDLVRGIIAEGNEKARDVARQTLDEVHQA
                     MGMNYR"
     gene            3837..>4598
                     /locus_tag="EKO19_RS39995"
                     /pseudo=""
     CDS             3837..>4598
                     /GO_process="GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /GO_process="GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018952816.1"
                     /locus_tag="EKO19_RS39995"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="segregation and condensation protein A"
                     /pseudo=""
                     /transl_table=11
                     /translation="MPFAVVEGEPMTQLPRDLYIPPDALQVFLTAFEGPLDLLLYLIRK
                     QNLDILNIPIAEITRQYMKYIEVMAELQLELAGEYLLMAAMLAEIKSRMLLPRPPSAEG
                     TDEDDPRAELVRRLQEYERFKKAAEDLDKLNRLERDNVLASAELEERQVVKLLPDVTLK
                     EMLDAFRDVLSRAEKFAHHHISRERLSQRERMTEILARLQTVAFFEFRQLFKPEEGRMG
                     VTVTFIAILELMKEGLIEIVQAEAYAPIHVRT"
     misc_feature    complement(4697..4711)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.39"
                     /tool="antismash"
     misc_feature    4821..4835
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.38"
                     /tool="antismash"
     misc_feature    complement(4967..4981)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.79"
                     /tool="antismash"
     misc_feature    5948..5963
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.15"
                     /tool="antismash"
     misc_feature    6065..6080
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.15"
                     /tool="antismash"
     gene            6554..7795
                     /gene="scpB"
                     /locus_tag="EKO19_RS23750"
     CDS             6554..7795
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /GO_process="GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="scpB"
                     /inference="COORDINATES: protein motif:HMM:TIGR00281.1"
                     /locus_tag="EKO19_RS23750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="WP_129779215.1"
                     /transl_table=11
                     /translation="MNEHDLKHIIEATLLAAGKPITTQQLMDLFEERERPTPEFFTTAI
                     GMLIADYENRGIELVEVASGWRIQVRPKAAEVVSRLWSERPAKYSRAFLETLALIAYRQ
                     PITRSEIEEIRGVSISSTIMRTLQERGWIRTVGHREVPGRPELLGTTREFLDYFGLKSL
                     DQLPTLAELKDIETIGVQLELQADQPQPIEGSAEGEVAASTEEGAATTEEAAASGEAAI
                     ESGGEIVASAEGAAAAVEAGAEADAEAGIDGETVAKADDSGRDADDEDAEDTDADADAE
                     EEEDEDDEDEDEDEEEEDEEEEDEEEEEEEEEEEDDDFGDDDDDDDAEDEDEDDDADFD
                     DDEDDDDDFDEDDDESEDKLSADAGDSDESNDADDELSADADEGDDESGTSSPMVASDH
                     DEEHTRVSEPPSEG"
     gene            7831..8673
                     /locus_tag="EKO19_RS23755"
     CDS             7831..8673
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1154: Pseudouridine synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013045.5"
                     /locus_tag="EKO19_RS23755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="S4 domain-containing protein"
                     /protein_id="WP_129779217.1"
                     /transl_table=11
                     /translation="MSERLHKLLAQHGLGSRREIEKWMLEGRVRLNNQPAQPGDRYNAG
                     DRVSIDGKDVTSRLSVFAAPKVILYHKPQGQPITPTAEDESGEVAGKSVMESLPSLRGS
                     RWLVVNTMQAGDSGLLLLTSDGRLADALRRRAETTPAAYVARVLVPFPEYDVDSIPRVV
                     QYDDETIEFENIEPAGGEGTNRWFRVESHRAHRRAAVRALFESRGLKVSRVIQVQFGEF
                     ELPRDLPRGKHRELSDSEVAELYASVELTLPTPPPKPEAPARPRRRPAPDRRKKPKRR"
     gene            complement(8705..9124)
                     /locus_tag="EKO19_RS23760"
     CDS             complement(8705..9124)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008528627.1"
                     /locus_tag="EKO19_RS23760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glyoxalase/bleomycin resistance/extradiol
                     dioxygenase family protein"
                     /protein_id="WP_129779219.1"
                     /transl_table=11
                     /translation="MSAAQSETPYPNPEVKGGLVAYLCVDGASKASDFYVKAFDAREVF
                     RYPVDDKGRTMHIHLYVNGSSLMLADGYPEHGHPCEQPQGFNLTLQVKNIDQWWQRAVD
                     AGAEIVLPLQDMFWGARYGQLKDPFGVLWSMNEPK"
     gene            complement(9214..9963)
                     /locus_tag="EKO19_RS23765"
     CDS             complement(9214..9963)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (17-157). E-value: 1.8e-07.
                     Score: 23.2. Matches aSDomain:
                     nrpspksdomains_EKO19_RS23765_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008735051.1"
                     /locus_tag="EKO19_RS23765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YciK family oxidoreductase"
                     /protein_id="WP_129779221.1"
                     /transl_table=11
                     /translation="MTDPRTYQPSKDALKDRVILITGASDGIGKAVAIAAATHGAQVVL
                     HGRNVRKLEAVYDEIVKGGHPRPSILPLDFEKAGPDEYEKLVTALDQEFGRLDGLLHNA
                     SMLGERAPIEHHDVAKWLRTMHVNVNAPFILTRTCLPLLKKSPDPVILFTSSGVVSNPR
                     PFWGSYLVSKWASDGLMSMLAQELEKQPAMRVNSINPGAVKTNMRLQAYPAEDRSKLRE
                     AHTIVAAYLYLLGPDSRGVQGQTLNAQ"
     aSDomain        complement(9493..9912)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EKO19_RS23765_PKS_KR.1"
                     /evalue="1.80E-07"
                     /label="EKO19_RS23765_PKS_KR.1"
                     /locus_tag="EKO19_RS23765"
                     /protein_end="157"
                     /protein_start="17"
                     /score="23.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VILITGASDGIGKAVAIAAATHGAQVVLHGRNVRKLEAVYDEIVK
                     GGHPRPSILPLDFEKAGPDEYEKLVTALDQEFGRLDGLLHNASMLGERAPIEHHDVAKW
                     LRTMHVNVNAPFILTRTCLPLLKKSPDPVILFTSSG"
     gene            complement(10001..10834)
                     /locus_tag="EKO19_RS23770"
     CDS             complement(10001..10834)
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012705.5"
                     /locus_tag="EKO19_RS23770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="squalene/phytoene synthase family protein"
                     /protein_id="WP_129779223.1"
                     /sec_met_domain="phytoene_synt (E-value: 1.3e-21, bitscore:
                     72.9, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 2.1e-24,
                     bitscore: 82.2, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSILENELVNRTAPPGSMRYFSLLYSPEDKRDAVLALYVIDTEIR
                     ESAKSASHDVAHTRLTWWRAETDRLVNGNPQHPATRVLNEHASGDRAIFSKLHEVLAAA
                     DMDLARMTFSNQQELRAYCSRSGGAIQELIAALLAQPGALDETTRAAANKLGVGIRMAE
                     IVRDLRQDAYDGNVYLPLDLLDRQELKTDHLRAREVDPKLKTALSSIRDSAAAELELPP
                     RGRQTESLRPAFVLAALHRKLLDHIAARHYDVASQRIELGPLQKPWTAWRAARRA"
     gene            complement(10839..12155)
                     /gene="rmuC"
                     /locus_tag="EKO19_RS23775"
     CDS             complement(10839..12155)
                     /codon_start=1
                     /gene="rmuC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018231581.1"
                     /locus_tag="EKO19_RS23775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DNA recombination protein RmuC"
                     /protein_id="WP_217705543.1"
                     /transl_table=11
                     /translation="MPELVGTSIGLMVLAALVGALVGALVASLRARQRSEGLHVELAVL
                     KAQVKGEEQLERERQAALERSMEKMKSQFDTLAGSSLRTNSELFLQLAREHLTQHQQYA
                     VSALTEREKAIETMLAPIREALGKTEQQIVRIEKERAETFGSLKTSLETVALGQQALQK
                     ETRTLVNALRRPEVRGQWGEMTLRRLAELAGMVEHCDFKEQVHVRIEDGNLRPDMIVHM
                     PDGRDLVVDVKTPLDAYLEAVDAATDEARAVAMRRHANAIAERVKQLGAKSYWAQFERS
                     PDFVILFIPGDQFLSAALAEQPNLLEDAIRQDVIIATPSSFVALLKAVAYGWRQMSLAQ
                     NAETIRTLAEDLYKRLAVFTTHLGKLGRNLSSSVDHFNAAVGSLERQVLPGARKFTELG
                     VRPDRELETLEPIDKMTREPAEKDQLPLPGTNDKAAQSK"
     gene            complement(12148..12858)
                     /gene="ubiG"
                     /locus_tag="EKO19_RS23780"
     CDS             complement(12148..12858)
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /GO_function="GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ubiG"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004203549.1"
                     /locus_tag="EKO19_RS23780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="bifunctional 2-polyprenyl-6-hydroxyphenol
                     methylase/3-demethylubiquinol 3-O-methyltransferase UbiG"
                     /protein_id="WP_129779225.1"
                     /transl_table=11
                     /translation="MNATASNHDPAEIARFDDIAQRWWDPKGEFRPLHVLNPVRLDYVD
                     EGASLRGKRVLDVGCGGGILSEAMAKRGARVTGIDLAPQTIEVAGLHALESQLTIRYMR
                     ESAETHAAHSPGAYDIVTCMEMLEHVPEPESVLRALHDLVKPGGDIFVSTLNRNLKAYL
                     LAVVGAEYVLNLLPRGTHSYERFIKPSEMSRWARSTGLNVVDIAGLAYDPLQHTARRTG
                     DVSVNYMMHLKRDA"
     gene            complement(12855..14141)
                     /locus_tag="EKO19_RS23785"
     CDS             complement(12855..14141)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012638098.1"
                     /locus_tag="EKO19_RS23785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="amidohydrolase family protein"
                     /protein_id="WP_129779227.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 1e-44, bitscore:
                     149.0, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEPIDTLLSARWIIPIEPAGVVLEAHSLAIHQGRILAVLPTAEAK
                     QRFSAQEELDRPAHVLLPGLVNAHTHAASSLLHGAVASSSFEHWAHTIRQLQRRWVDAE
                     YVRDGTELAIAAALSSGTTCFADQHLFPEVVAQTAAEARMRVCVGLPVQDTPSVWAGSA
                     SECLDKGFKLRDEYRDDPLITTALAPVEPAALSDDTLERLRRLADELELPIYMHVNESR
                     GSAPSLERLEQLGLLSPLLAAVHMVKLDSADVERVAAAGASVVHCPQSNLKLGSGLCPV
                     PLFKDRAVNVALGSGGVGNHDLLAELRTAALIANGMFPAATPVDAHDWLQTATLNGARA
                     LGLAESIGSLLPRKWADVCCIDLGQPNTQPTYDPAAQIVYAASREQVSDVWVAGRTLVR
                     DRQLTHIDTAALLNRAELWRVRIAAQVTE"
     gene            14236..16905
                     /gene="gyrA"
                     /locus_tag="EKO19_RS23790"
     CDS             14236..16905
                     /EC_number="5.6.2.2"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA]"
                     /GO_function="GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006259 - DNA metabolic process [Evidence
                     IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="gyrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011628672.1"
                     /locus_tag="EKO19_RS23790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DNA gyrase subunit A"
                     /protein_id="WP_129779229.1"
                     /transl_table=11
                     /translation="MAEIAREILHVNLEDEMRQSYLDYAMSVIVGRALPDVRDGLKPVH
                     RRILFAMHESNNVYSRPYVKCARVVGDVLGKYHPHGDTSAYDALVRMAQNFSMRYQLVD
                     GQGNFGSVDGDPPAAYRYTECRMTQLASELLADIDRETVDFVDNYDGKEKEPVVLPTRV
                     PNLLINGSAGIAVGMATNIPPHNLGEVVTACIALIDDPSITIATLMQIIPGPDFPTAGI
                     INGAAEIASAYLTGRGRVYVRAKTDIEEDDKGRQAIIITELPYQVNKARLLERIAELVR
                     EKVVEGIASDGLRDESDKDGMRVVIELKRGEVADVVLNKLFKHTPMETVFGMNMVALQD
                     GQPKLFNLKEMLEAFVRHRREVVTRRTVFDLRKARERAHILEGQAVALANIDEVIALIK
                     ASPTPPEAKVALMSRIWTSGAVPAMLERAGDIVSRPDGLSIEFGLVEGGYRLSDVQAQA
                     ILDMRLNRLTGLEQDKIIAEFQELLTQIADLSDILARPERLLQVIRTELEEVKAKYADP
                     RRTQINFDHSDLTIEDLIEQQDVVVTLSHGGYAKSQPVTDYQAQRRGGRGKSATAMKDE
                     DFVDKLFVANTHDTLLCFSSTGKLYWLKVYQLPQASRGSRGKPIVNLLPLQEGERINAV
                     LPIHEFEENKFVFMVTAAGTVKKTSLEAFSRPRQAGIIAIELEQGDRLVGVDITDGTKQ
                     IILCSSGGKAIRFDENDVRPMGRTAAGVRGIRLPEPTPAAEGAELPATAAEEVISLIIV
                     DEQGMVLTASENGYGKRTAIEDFPIHGRGGQGVIALQISERNGRMVGALLVKPEDEIML
                     ISSGGTLVRTQVNEISVQGRNTQGVRLIRVDEGDRLVGLERIVSEGAGEAGAEGAEGEG
                     GEGDAGGDDGGGAAPDSA"
     gene            16945..18027
                     /gene="serC"
                     /locus_tag="EKO19_RS23795"
     CDS             16945..18027
                     /EC_number="2.6.1.52"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0004648 -
                     O-phospho-L-serine:2-oxoglutarate aminotransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006564 - L-serine biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_5 (2-347). E-value: 1.3e-55.
                     Score: 180.7. Matches aSDomain:
                     nrpspksdomains_EKO19_RS23795_Aminotran_5.1"
                     /codon_start=1
                     /gene="serC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008932231.1"
                     /locus_tag="EKO19_RS23795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="3-phosphoserine/phosphohydroxythreonine
                     transaminase"
                     /protein_id="WP_129779231.1"
                     /sec_met_domain="Aminotran_5 (E-value: 4.7e-57, bitscore:
                     189.5, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVYNFSPGPAVLPQEVLEQAREEMLDWHGTGMSVMEMSHRGKAF
                     IAIAEQAEADLRELLSIPKNYKVLFLQGGAFGQFAGVPMNLSKPGDTVDYVNTGAWSKK
                     AISEAKAYAKVNVAADAGEPYTSIPLLSNWQVSENAAYLHYTPNETIGGVEFHFVPELK
                     SGTPLVVDMSSTLLSRPIDVSKFGLIYGGAQKNVGPAGLTLVIVREDLLGHARPGTPSF
                     MDYGAMAKEGSMLNTPPTYAWYLAGLVFQWLKRQGGLKAMGEINRRKAELLYSAIDTSS
                     FYKNPVAHDARSWMNVPFTLARPELDKTFTSEAKDAGLVTLEGHRSVGGMRASIYNAMP
                     LAGVEALVSFMKEFERKHAG"
     aSDomain        16951..17985
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EKO19_RS23795_Aminotran_5.1"
                     /evalue="1.30E-55"
                     /label="EKO19_RS23795_Aminotran_5.1"
                     /locus_tag="EKO19_RS23795"
                     /protein_end="347"
                     /protein_start="2"
                     /score="180.7"
                     /tool="antismash"
                     /translation="VYNFSPGPAVLPQEVLEQAREEMLDWHGTGMSVMEMSHRGKAFIA
                     IAEQAEADLRELLSIPKNYKVLFLQGGAFGQFAGVPMNLSKPGDTVDYVNTGAWSKKAI
                     SEAKAYAKVNVAADAGEPYTSIPLLSNWQVSENAAYLHYTPNETIGGVEFHFVPELKSG
                     TPLVVDMSSTLLSRPIDVSKFGLIYGGAQKNVGPAGLTLVIVREDLLGHARPGTPSFMD
                     YGAMAKEGSMLNTPPTYAWYLAGLVFQWLKRQGGLKAMGEINRRKAELLYSAIDTSSFY
                     KNPVAHDARSWMNVPFTLARPELDKTFTSEAKDAGLVTLEGHRSVGGMRASIYNAMPLA
                     GVEAL"
     gene            18050..19249
                     /locus_tag="EKO19_RS23800"
     CDS             18050..19249
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2-Hacid_dh_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1072: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013219258.1"
                     /locus_tag="EKO19_RS23800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="WP_129779233.1"
                     /sec_met_domain="2-Hacid_dh_C (E-value: 2e-36, bitscore:
                     120.9, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGQSVEGNDVAYRILMLNNISVRGLERLPRERYEIASALSNPDA
                     VLVRSADMHSIELPASVIAVGRAGAGTNNIPVSRLSARGIPVFNAPGANANAVKELVIA
                     GLFLAARNICQAWDYARNLKGSDEELEVAVEQGKKKYVGYELPSRTLGVIGLGAVGVEV
                     ANAAHLLGMRVLGFDPQITVQRAWQLSSGVQQALSLDDLFSRCDMVTVHVPLIEATRGF
                     VNAARIRLLRDNGVVLNFSRAGIVDEKAVVEALDSGKLGAYICDFPTNGVKHHPKIVAL
                     PHLGASTGEAEENCAIMVADTLKDFLENGNIRHSVNFPEAVLPRTASSTRLSISNENVP
                     NMVGQISTALAHARLNIADLLNKSRGELAYTLIDVDGQVPAGVLDQLRKIEGVLNVRAL
                     "
     gene            19313..20476
                     /gene="pheA"
                     /locus_tag="EKO19_RS23805"
     CDS             19313..20476
                     /EC_number="4.2.1.51"
                     /GO_function="GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="pheA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013535389.1"
                     /locus_tag="EKO19_RS23805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="prephenate dehydratase"
                     /protein_id="WP_129779235.1"
                     /transl_table=11
                     /translation="MKRTPKAGSRKAVSKKAAARKAPASVPAELSSIRQQIDAIDQHIH
                     ELLNERARFAQQVGESKRGEGMSTADFYKPEREAQVLRNAIERNKGPLRNDEIVRLFRE
                     IMSACLAQQEPLKIAFLGPEGTFSQQAVLKHFGHSVRALPLPAISEVFEEVQAGHADFG
                     VVPIENSTEGTVNHTLDMFLNSPLKICGEIELRIRQHLMGRMKGLQKISRVCSHPQSLA
                     QCRQWLDEHLPNIERVPVSSNAEAARRARDEDGTAAIAGEAAAEVYNLGVLVPEIEDTA
                     DNTTRFLVVGRKLFSASGQDKTTLLVSAGDTQSPGALHRLLGPLADNDITMTRIESRPS
                     RKRKWDYVFFIDVIGHAEQPPLSTALDELRKASTLFRVLGSYPAAVL"
ORIGIN
        1 gaagggctgg accacgctcg agtgagcgct caggtctttt tctcgatctt ggcgttcttg
       61 cgcagctcat ccagatagtt ctgcagcttc ttccgctgca ccagcatctt gacccggtcc
      121 ttgacctcgt cgaacgccgg cgcctgagtg gtgcgggact cttcgagctt gatgatgtgc
      181 cagccgaact ggctctgtac cggctgatcc gtcatctgcc ccggctgcag cgccgcgacc
      241 gcgtcggaga acggcttgac catggtctcg agcgtgaacc agccgagatc gccgccgttc
      301 ttgccggagg gatccttcga gttcttttcc gccagcttgg cgaaatccgc gccgcccttg
      361 agctccttgg tgagcgcctc ggccttggcc tggtcgtcca ccagaatgtg tcgtgcgtga
      421 tattccttag gcatctgcgc gacctgcgcg tcatattccg ggcgcagctc cgcgtccgtc
      481 accgggttct tctccagcca ctcctggagg ccggaatcga ccagcacgtt gaggcgggcg
      541 agggcgagct gatcctggac cttgggctgc ttttcgatgc ctgccttgga ggccgcttcg
      601 gccgccagct gcatgctgat gaactgatcc agcagctgcg acttttcggc ttcggagatc
      661 tcgcgcttgg actggcgccc gacgttctcg acgtacaggt cgaactccga cttgctgatg
      721 ttcttgccat tgaccaccgc gaccggcggg ccggcggggg ctttttggct ttcggcggca
      781 ttgccgcagc cggccagcag cgtcagaggc agcagcaggc cgacgaggag atgacgattc
      841 atgggagtcc ttgatgtgga agttatctga aagatattcg tcagcgcgct tcgtccggtg
      901 tcagcgcggt gatgctcaat gcgtggatgt cggtctgcat gagatcgccc agcgaccggt
      961 aaaccagctg gtgccgctgc agcgtgcgca ggccgccaaa gtcggcggac acgacgcgca
     1021 cgcgaaaatg ccctcggcca tctctcgcac ccgcatgacc ggcgtgcaga tggctgtcgt
     1081 cgatcaactc gacctgctcg gtgtgcaatg ccttgcgcag ctcaccgacg atgcgctcgg
     1141 cgcgggtcac tgcggcttct ccgacggggc cgaggtgtcc tcgggcggca tcttggacga
     1201 cagccagatc gcctgcgcga tcgcgaacac cacggtcagc ccgagcatgc cgaacagctt
     1261 gaagttgacc cagacctctt cggagaagtt gtagacgata tagaggttga tgatgccgag
     1321 cgcggtgaag aacacgatcc aggcccagtt cagcgtgcgc cataccggcg ggtccagctg
     1381 cacgttctcg cccatcatcc gttcgatcag cagtttgtcg ccaaaaaacc ggctggcgag
     1441 gaaaccggcc gcgaacagcc agttgaccac cgagaccttc cactggatga aaaccttgtc
     1501 atggatcagc agcgtcaaac cgccgaaaat caataccagc acgcccgaga tcagcgccat
     1561 ctggctgacc ttgcggtggc ggaaccattg ccaggccgtc tgcgctatca ccgcgacgat
     1621 gatcacgccg gtggcgacga acaggttgcc ggtgatcttg taggtgagaa agaacgcgat
     1681 gaccggaaag aagtcgaaca acaacttcat gagaggacgc ggaccttgcc ggtcgaccgg
     1741 cggatttgac agggccgcta tcataccggg atgaccagcc gctatttgga gattcacccc
     1801 agggacccgc agctccgcct gatccgtcag gcggtcgaga tcattcgtga gggcggggtg
     1861 gtcgtttatc cgaccgattc gtgctacgcg cttggctgcc acctcggcga caaggcggcc
     1921 atggagcgca ttgcccgcat tcgccagacc gaccgtcatc accacttcac attggtgtgc
     1981 agcgacctgt cggagatcgc caactacgcg cgcgtcagca acacgcagta ccgcacgctg
     2041 aaggcgttca cgccggggcc atacaccttc atcctgcagg ccaccaagga gacgccgcgg
     2101 cgcctgcaga acgagaagcg caagaccatc ggcgtgcgtg tgcccgacca tcccgtggtc
     2161 accgccatcc tcgacgagct gggcgaaccg atcatgagct cgacgctaat cctgccgggc
     2221 gacgagcatc cgctgaccga tccgcgcgag atccaggagc ggctgtttca cttcgtcgac
     2281 gcggtgatcg acagcggcaa ctgcgggctc gagccgagca gcgtgatcga cctggccggt
     2341 cccgcgccgg tcgtggtccg ccggggcaag ggcgacgtga gcgcgttcga ataatgcgac
     2401 tcatcggcag ctatcaagag tggctgtcaa gctgcgtata atgccgccag cttcacaagc
     2461 tgctgatttc ccgaattaac aagattcgct aacgccttga tttttaggtc gtaaggatag
     2521 gcattgagct cgactcccgc taccaaccga cgcgtcctgt ccggcatgcg cccgacaggt
     2581 gcactccatc ttggtaacta tcacggcgcg ctcaagaact gggtggagct gcagtaccag
     2641 tacgagtgct acttcttcgt cgcggacatt catgcgctga cgaccggtta cgaggacact
     2701 tcgcaactcg agagcaatgt ctggaacgtg gtgatcgact ggctggccgc cggtctgaac
     2761 ccggcgtcct cgaccatctt cattcagtcg cgcgtgcccg agcactccga gctgcatctg
     2821 ttgctgtcga tgatcacgcc gctcggctgg ctggagcgcg tgccgaccta caaggatcag
     2881 caggagcagc tcaaggacaa ggatctcgcg acctacggct ttctcggtta tccgttgctg
     2941 cagtcggccg acatcctgtt gtacaagacc gccttcgtac cggttggcga ggaccagatc
     3001 gcgcacgtgg agatcacgcg cgaagtggcg cgtcgcttca atcatgtcta tggccgcgag
     3061 cccgacttcg aggccaaggt ggataaggca ctcaaggcat tgggcagtcg caacggcact
     3121 cgatacaacg agttgcggcg tctttatcag gagaagggcg atcaggaagc catcgccaag
     3181 gcgcactcgc tgctggaagg cacggcgcgg ctgaccctgg ccgatcgcga gcgcctcatc
     3241 ggctatctgg aaggcacggg ccgcagctat ctggtcgagc ccgaagtgct gctgacggcg
     3301 acgccgaagg tgcccggcct cgacggtcgc aagatgtcca agtcctacgg caacaccatc
     3361 ggcctgcgcg aggatcccga tcaggtcgcg aagaagctga agggcatgat gaccgacccg
     3421 gcgcggcagc gtcgcaccga tccgggcgat ccggacaagt gcccggtgtt cgatctgcac
     3481 aagatctatt cgtcgaccga gacgcaggcg tgggccgcgc agggctgtcg ctccgccggc
     3541 atcggttgtc tggattgcaa gaagccggtc atcgatgcaa tcgtgaccga gctgcgcggc
     3601 atgcaggcac gtgccaagga attcgaagag aatcgcgacc tggtccgagg catcatcgcc
     3661 gagggcaacg agaaggcgcg cgacgtggcc cgccagacac tcgatgaggt gcaccaggcg
     3721 atggggatga actaccggtg agcaaggcca agcccgaact gaagctggtg gaagacaccg
     3781 gctcgcagct gcaggacgag gacctgagcg ccgaattgcc gccccagcag agcgagatgc
     3841 cgttcgccgt cgtcgaaggc gagccgatga cgcagctgcc gcgggatttg tatattccgc
     3901 cggatgcgtt gcaggtgttc ctgaccgcgt tcgaaggtcc gctcgatctg ctgctgtatc
     3961 tgatccgcaa gcagaacctc gacatcctga acattccgat cgccgagatc actcgtcagt
     4021 acatgaagta catcgaggtg atggcggagt tgcagctgga gctcgccggc gaatatttgc
     4081 tgatggccgc gatgctcgcg gagatcaagt cgcgcatgct gttgccgcgg ccgccgtcgg
     4141 ctgagggcac ggatgaagac gatccgcgcg ccgagctggt gcgtcgtctg caagagtacg
     4201 agcgcttcaa gaaagcggcg gaggatctcg acaagctgaa tcggctggag cgcgacaacg
     4261 tgctcgcgtc cgccgagctg gaagagcgcc aggtcgtcaa gctgctgccg gacgtgacgc
     4321 tgaaggaaat gctcgacgca tttcgcgacg tgttgtcccg cgccgagaag ttcgcgcatc
     4381 accacatctc gcgcgagcgc ttgtcgcagc gtgagcgcat gacggagatt ctggcgcgct
     4441 tgcagacggt cgcgttcttc gagttccgcc aattgttcaa gcccgaagaa gggcgcatgg
     4501 gcgtcactgt gacgttcatc gccattctgg aattgatgaa ggaaggcttg atcgaaatcg
     4561 tgcaagctga ggcttacgcc cccatccacg tacgcaccgc gcagcggcac ctgaaagtcg
     4621 ttcagggtgg cgtcgcggct tcggagacgg ccgacgcgga gaacgccgcg gcgctcgcgc
     4681 agccggagct ggcgggtgag aacgatattc cagatgacga cgacacgccg ccggccgatg
     4741 acgctgccat cgccgtgcag gaagctgttg ccgatgtggc tgcggcgtct tcgattgcgg
     4801 tcgacagcat cgagtcggat aacacgattg tcgatgcggg ctttgttgaa gccgcggtgt
     4861 cggaggcgat tgcgtcgacc gagaatgcgg tggagaccgt cgccgaagtc gctgcgactg
     4921 atgaggcggc cgttgccgcc gcggtggccg aagaggttgc tgctggatcg ccggtggtga
     4981 tcgatgaggc ggcgctcgag tcctccgagg gtcgagaggt cgcgatcgat gcagcggtga
     5041 tcgaagcggc cgccgccgat ctcgcggcag aagattcgtt gccggctgag ccgggggccg
     5101 tcgatgttgc gacggacggc tcgttgctga ttgagtcggc cggcgccgat atcgcgattg
     5161 aaggattgct gattgagccg gccacgcttc aggtcgtgac cgatgagttg tcggtgaact
     5221 cgcacgttta tgacgaggtc accctcgaag acgtgccgca tgattttggc gccgtggatt
     5281 ccgccctcgc cgacgaaaca gatccgctga cggcgcaggc cgtcgagcag gtcgctgagc
     5341 tcagcgtgtc gccggtgatg gatgtcctcg cggagggcga gttgacacag gccggcctca
     5401 tcgaaggcac ggtcgccgac gcgcctgaat cggttgaggc gctggtgtcg atttacacgc
     5461 cggagccggt ggagacgacc gaagcggtcg agccgaacga ggcagctggg ctggctgaga
     5521 cgaccgaagc ggtcgacgtg accgaggtcg tcgggctgac cgagaccact gaagccgtcg
     5581 agccgaacga ggttgtcggg ctgactgaga cgaccgaagc ggtcgagtcg accgaggtca
     5641 tcgggctgac cgagatgacc gaagcggtcg agccgaacga ggccgtcgcg gcgatcgaga
     5701 gtgttgacgt cgttcccggc gacgagcgca cggttgaaga acacgtcgtc gaggagcacg
     5761 aagtcgagga acacatcgtt cccgagcacg tggtcgaaga gcacgtcgtg cccacgccgg
     5821 tggtgatcga agagaacacg tcgcagacgg atgcagccgc gttcgtcgat gagtccgtcg
     5881 cccggtcgga agccgaggtt gttgtcgacc aggtcgaggc agctgacggc gtcgacggag
     5941 ttgtcgacca ggtcgagacc gctgaggtgc tcgacgaagt ggtcgatgag gtcgaggcag
     6001 ctgaagccgt cgacggagtg gtcgatgagg tcgaggcagc tgacggcgtc gacggagttg
     6061 tcgaccaggt cgagaccgct gaggtgctcg gcggagtggt cgatgaggtc gagacagctg
     6121 acgtcgtcga cgaggttgtg tctcgagccg agccggtgga gatcaccgac gaagtcgtcg
     6181 catcttccga cttcacgacg gccgaagtcg tggaagagga agtcgtggac gagcattcgc
     6241 agccggtcga gacgacggat gtcgtcatga ccgaggcagc gccagcggtc gaagcagttg
     6301 aagtcgctgc ggccgtcgag gatgcgccgg ctgatgaaac gatcgaagtc gccgccgggc
     6361 aagtaccggc tgaagaaacg accaacgtgg tgatcgagga tgcgccggcg ccggttacgg
     6421 ccgatgcggc cgggcatgac gaagcgacca ccgagcagac tgccgacctg tccgggcctg
     6481 atctgtctaa tgcaggcgac agcgtgaccg gagcctccga cgaggctgac aatacggacg
     6541 cggaaccaac gagatgaacg aacacgatct caagcacatc atcgaagcga cgctgctggc
     6601 ggcgggcaag ccgatcacca cgcagcagct gatggatctc ttcgaagagc gcgagcgccc
     6661 cacgcccgaa ttcttcacca ccgccatcgg catgctgatc gccgactacg agaaccgtgg
     6721 catcgagctg gtcgaagtcg cgagcggctg gcgcatccag gtgcggccga aggccgccga
     6781 agtcgtatcg cgtctgtggt cggaacgtcc ggcgaagtat tcgcgtgcgt ttctggaaac
     6841 attggcgctc atcgcctatc gccagcccat cacccgcagc gagatcgaag agatccgcgg
     6901 cgtgtcgatc agctcgacca tcatgcgcac gctccaagag cgcggctgga ttcgcaccgt
     6961 cggtcaccgc gaagtcccgg gccgtccgga actgctcggc acgacgcgtg agttcctgga
     7021 ttacttcggt ctgaagagcc tggatcagct gccgacgctc gccgagctga aggacatcga
     7081 gaccatcggt gtgcaactcg agctgcaggc cgatcagcct cagcccatcg aagggtcggc
     7141 tgaaggtgaa gttgcggcga gcaccgaaga gggcgcggcg acgacagaag aagctgcggc
     7201 gagcggcgag gccgctatcg agtccggtgg tgaaattgtg gcgagcgcgg aaggcgccgc
     7261 cgccgccgtc gaagcaggag cagaggctga cgcggaagcc ggcatcgacg gcgagacggt
     7321 cgccaaagcc gacgacagcg gccgtgatgc cgacgacgaa gacgccgaag acactgacgc
     7381 cgacgccgac gccgaagagg aagaggacga agacgacgag gacgaggacg aggacgaaga
     7441 ggaagaggac gaagaggaag aggacgaaga ggaagaggaa gaggaagagg aagaagaaga
     7501 cgacgacttc ggcgatgatg acgatgatga cgacgccgaa gacgaagacg aagacgacga
     7561 cgccgacttc gatgacgacg aagacgatga cgacgacttc gatgaggacg acgacgagag
     7621 cgaggacaag ctgtcggccg acgctggtga cagcgacgaa tcgaacgacg ccgacgatga
     7681 attgtccgcc gacgccgatg agggcgacga cgagtccggt acctcatcgc cgatggtcgc
     7741 atcggaccac gatgaagagc acactcgcgt cagcgagcca ccgagcgaag gctaacccac
     7801 cggcaccgct gcacccgcgg tgcccgaatc atgtccgaac gtctgcataa actcctggcc
     7861 cagcacggcc tcggctcgcg tcgcgagatc gagaagtgga tgctggaagg ccgtgtccgt
     7921 ctgaacaatc agccggcgca gcccggcgac cgttacaacg cgggcgatcg ggtcagcatc
     7981 gatggcaaag atgtcacatc gcggctgagc gtcttcgcgg cgccgaaagt gatcctgtat
     8041 cacaagccgc aaggccagcc gatcacgccc accgcggaag atgaaagcgg cgaggtggcg
     8101 ggtaaatccg tcatggaatc gctgccgtcg ttgcgcggct cgcgctggct ggtcgtgaac
     8161 accatgcaag cgggcgacag cggattgttg ttactgacga gcgatggtcg cctggccgac
     8221 gcgcttcgcc gccgcgctga aacgacgccg gcagcgtacg ttgcacgcgt gctcgtgccg
     8281 tttcccgaat acgacgtcga ctccattcct cgcgtcgttc aatacgacga cgagaccatc
     8341 gagttcgaaa acatcgagcc ggccggcggc gagggcacga atcgatggtt ccgcgtggaa
     8401 tcgcatcgtg cgcatcgtcg cgccgccgtg cgggcattgt ttgaaagtcg cgggttgaaa
     8461 gtcagccgcg tgattcaagt gcagttcggc gagttcgagc tgccgcgaga tctgcctcgc
     8521 ggtaagcatc gtgagctgtc ggacagcgag gtcgctgagt tgtatgcgag cgtcgagctc
     8581 acattgccga cgccgccgcc caagccggaa gcgccggccc gtccgcgccg ccggcccgcg
     8641 cctgatcgac gcaagaagcc gaagcggcgc tgacctcgga agtaacaatc gaaagtaaca
     8701 atcgttactt cggctcgttc atcgaccaca gcacgccgaa cgggtctttc aactggccgt
     8761 agcgggcgcc ccagaacata tcctgcagcg gcagcacgat ctccgcgccg gcatctaccg
     8821 cgcgctgcca ccactggtcg atgttcttca cctgcagcgt caggttgaaa ccctgcggct
     8881 gctcgcaggg gtggccgtgc tcgggatagc cgtcggccag catcagcgac gagccattga
     8941 cgtaaagatg gatgtgcatg gtgcggccct tgtcatccac cggataacga aacacttccc
     9001 tggcgtcgaa tgccttcacg tagaagtcgg acgccttgct ggcgccatcc acgcacagat
     9061 aggcgaccag gccgcctttg acttcgggat tcgggtaggg agtttcgctc tgcgccgcgc
     9121 tcattttctg ctcctgttgc gagtggaacc ggtcgttcga ggcaaggacg ccgccgccga
     9181 ccggttcccg acacaggcgg gcaaaaaagt cggctactgg gcgttgaggg tctggccctg
     9241 gacgccgcgg ctatcgggcc cgagcaagta aagatacgcc gccacgatgg tgtgagcttc
     9301 gcgcagcttg ctgcgatcct cggcggggta ggcctgcaat cgcatgttcg tcttcaccgc
     9361 gcccgggttg atgctgttca cgcgcatcgc cggctgcttc tccagttcct gcgccagcat
     9421 gctcatcaga ccgtcgctgg cccacttgga caccagatac gagccccaga acggacgcgg
     9481 attggagacg acgccgctgg aggtgaacaa gatcactgga tcgggcgact tcttcagcag
     9541 cggcagacag gtgcgcgtga gaatgaaggg cgcattgacg ttcacgtgca tggtgcgcag
     9601 ccatttcgcc acgtcgtgat gttcgatcgg cgcgcgttcg cccagcatcg aggcgttgtg
     9661 cagcaggccg tcgagtcggc cgaattcctg atcgagcgcg gtgaccagct tctcgtactc
     9721 atccgggccg gctttctcga aatccagcgg cagaatggat ggccgcggat ggccgccctt
     9781 cacgatctca tcgtaaaccg cttcgagctt gcgaacgttt cgaccatgca gcacgacctg
     9841 cgcgccgtgg gtcgcggccg caatcgccac cgctttaccg atgccgtcgc tcgcgccggt
     9901 gatgaggatg acgcgatctt tgagcgcgtc tttggagggt tggtaggtac gcgggtcagt
     9961 catattcttt gccagccata tgcttcgtcg gacgggcgga tcaagcacga cgcgcggcgc
    10021 gccacgcagt ccacggtttt tgcagcgggc cgagctcgat gcgctgggag gcgacatcgt
    10081 agtggcgggc cgcgatgtga tcgagcaatt tgcggtgcaa tgccgccagc acgaacgcag
    10141 gacgcagact ctccgtctgt cggccccgag gaggcagctc cagttcggcg gcggcactgt
    10201 cacggatgga gctcaatgcg gtcttgagct tcggatcgac ttcgcgggcg cgcagatgat
    10261 ccgttttcaa ttcctgccgg tcgagcaggt cgagcggcaa ataaacattg ccgtcgtacg
    10321 catcctgacg cagatcccga acgatctccg ccatgcgaat gccgacgccg agtttgttgg
    10381 ccgccgctcg cgttgtttca tcgagcgcgc ccggttgggc gagcagggca gcgatcaact
    10441 cctgaatcgc gccaccgcta cgagagcaat acgcacgcag ctcctgctga ttcgagaagg
    10501 tcatgcgggc gagatccatg tccgccgccg ccagcacttc gtgcaacttg ctgaaaatgg
    10561 cacgatcgcc ggacgcgtgt tcgttgagca cccgcgtcgc cggatgctgt ggattgccgt
    10621 tgaccagccg atcagtctcg gcgcgccacc aggtcagccg cgtatgagcg acgtcatgac
    10681 tggcgctctt ggcggattcg cgaatttcgg tgtcgatgac gtagagggcg aggacggcgt
    10741 cgcgcttgtc ttcgggcgag tacagcagcg agaaatagcg catcgagccc ggtggggccg
    10801 tgcgattgac cagttcgttc tccaggatcg acatggcgct acttggactg cgctgccttg
    10861 tcgttggtcc cgggcagcgg cagctggtct ttctccgccg gctcgcgcgt catcttgtcg
    10921 atgggctcca gcgtttccag ctcgcgatcc gggcgcaccc ccagctcggt gaacttgcgt
    10981 gcgccgggca gcacctggcg ttcgagcgaa ccgaccgcgg cgttgaaatg atcgacgctg
    11041 ctactcaggt tgcggcccag cttgcccaga tgtgtcgtga acaccgccag acgcttgtag
    11101 agatcttcgg cgagcgtgcg aatggtctcg gcattctgag cgagcgacat ctgccgccag
    11161 ccataggcga ctgctttcag cagcgcgacg aagctcgatg gggtcgcgat gatcacgtcc
    11221 tgacgaatcg cgtcttccag caggttcggt tgctcggcga gcgcggcgga caggaactga
    11281 tcgcccggga tgaacagaat cacgaagtcg gggctgcgtt cgaactgcgc ccagtagctc
    11341 ttcgcgccga gttgcttgac gcgctcggcg atggcgttgg cgtgacggcg catcgccact
    11401 gcgcgcgctt cgtcggtggc ggcatcgacg gcttcgagat aggcatcgag cggcgtcttc
    11461 acgtccacga ccagatcgcg gccgtcgggc atgtggacga tcatgtcggg acgcaggttg
    11521 ccgtcctcga tgcgtacgtg cacctgttcc ttgaagtcgc agtgctcgac catgccggcc
    11581 agctcggcca ggcgacgcag cgtcatttcg ccccactggc cgcgcacttc gggccggcgc
    11641 agcgcgttga ccagcgtgcg ggtttccttt tgcagcgctt gctggccgag cgcgacggtt
    11701 tcgagcgagg tcttcaggct gccgaaagtt tcggcgcgct ctttttcgat gcgcacgatc
    11761 tgctgctcgg tcttgcccag cgcctcgcga atcggcgcga gcatggtctc gatggctttc
    11821 tcacgttcgg tgagtgccga gaccgcgtat tgctgatgct gagtcaggtg ctcgcgcgcg
    11881 agttgcagga acagctcgct gttggtacgc agggacgagc cggccagcgt gtcgaactgc
    11941 gacttcatct tttccatcga acgttcgagc gcggcctggc gctcgcgttc gagctgctct
    12001 tcgcccttga cctgagcttt cagcaccgcg agctcgacgt gcagcccctc agaacgctga
    12061 cgcgcacgca gactcgcgac gagcgcgccg acgagcgcac ccaccagcgc ggccagaacc
    12121 atcaacccaa tcgaagtacc gaccaattca ggcatctctt ttcaagtgca tcatgtagtt
    12181 cacgctcacg tcgccggtgc gacgggcggt gtgttggagc gggtcatacg cgaggcccgc
    12241 gatgtccacg acattgagac cggtgctgcg ggcccagcgg ctcatctcgg aaggcttgat
    12301 gaagcgctca taactatgag tgccacgcgg cagcaggttg agcacgtact ccgcgccgac
    12361 caccgccaat agataagcct tgagattgcg attcaacgtc gagacgaaga tgtcaccgcc
    12421 gggcttcacc agatcgtgca gagcgcgcag cacgctttcc ggctcgggca cgtgttcgag
    12481 catttccatg caggtgacga tgtcgtaggc gcccggcgaa tgagccgcgt gggtctcggc
    12541 cgactcgcgc atgtaacgaa tcgtgagctg gctttcgagc gcatgcagcc cggcgacttc
    12601 gatggtctga ggcgcgaggt cgatgcccgt gactcgagcg ccgcgcttgg ccatcgcttc
    12661 gctgagaatg ccgccgccgc agcccacatc gagcacgcgc ttgccccgca acgaggcgcc
    12721 ctcatcgacg tagtcgagcc gcaccggatt caaaacgtgc agcggacgaa attcgccctt
    12781 cggatcccac cagcgctggg cgatgtcgtc gaagcgggcg atttcggccg ggtcgtgatt
    12841 ggaagcagtt gcgttcattc tgtcacctga gccgcgatac gaacgcgcca gagctcggcg
    12901 cgattcaaca gagccgcggt gtcgatatgc gtcagctggc gatcgcgcac cagcgtgcgg
    12961 ccggcgaccc agacatcgct gacttgctcg cgcgacgcgg catatacaat ctgcgcggcc
    13021 ggatcgtagg tgggctgagt attgggctgg cccaagtcga tacaacacac atcggcccat
    13081 ttcctcggca gcagcgagcc gatggactcg gccaggccga gcgcgcgtgc accgttcagc
    13141 gtcgccgttt ggagccagtc atgcgcatcg accggggtcg ccgcggggaa catgccattg
    13201 gcgatgaggg cggcggtgcg cagctcggcg agcagatcgt gattgccgac accgccgctg
    13261 cccaacgcca cgttcaccgc acgatccttg aataggggca cggggcacag gccgctgccg
    13321 agcttgaggt tggattgcgg gcaatggacg acactggcgc ccgcggcggc gacgcgttcg
    13381 acgtcggcgg aatccagttt gaccatgtga accgcggcga gcagtgggga cagcagcccc
    13441 agctgttcga gccgttcgag cgacggcgcg ctgcctcggc tctcgttgac gtgcatgtag
    13501 atgggtaatt ccagctcgtc ggcgaggcgc cgcaggcgtt ccagcgtgtc gtcgctgagt
    13561 gctgcgggtt ccaccggcgc gagcgcggtc gtgatcaaag gatcgtcgcg gtattcgtcc
    13621 cgcaatttga agcctttatc cagacactcg ctggccgaac cggcccagac cgacggcgtg
    13681 tcctgtacgg gtaggccgac gcagacacgc atgcgcgctt cggcggcggt ctgcgcgacc
    13741 acttctggaa aaagatgctg gtcggcaaaa catgtcgtgc cgctcgatag cgcggcggcg
    13801 atcgcaagct cggtaccgtc gcggacgtat tcagcatcga cccagcgccg ttgaagctgc
    13861 cggatggtgt gcgcccaatg ctcgaacgag ctgctggcga ctgctccgtg caacaggctg
    13921 ctggcggcat gcgtatgcgc gttcaccagc cccggcaaca gcacgtgcgc cggccggtcg
    13981 agctcttcct gcgcggaaaa acgctgtttc gcctcggccg tgggcaacac cgccaggatg
    14041 cggccctggt gaatcgccag cgaatgtgct tccagcacca cgcccgccgg ttcgatcgga
    14101 atgatccagc gggccgagag cagcgtgtcg ataggttcca tgggcgccgg agtatagctg
    14161 tgagaagtac caccggacgc cctgttttgg acgcgcgatg tgataagatt cgccacttcc
    14221 ttcgacgagt tccgcatggc cgaaatcgcg cgcgaaatcc tgcacgtcaa cctcgaagac
    14281 gagatgcgcc agtcgtatct cgactatgcg atgagcgtca tcgtcgggcg cgctctgccc
    14341 gacgtgcgcg acggcttgaa gccggtccat cgtcgcatcc tgttcgcgat gcatgagagc
    14401 aataacgtct attcccgccc gtatgtgaag tgcgcgcgcg tggtcggtga cgtgctcggc
    14461 aaatatcacc cgcacggcga cacgtcggct tacgacgcgc tggtgcgcat ggcgcagaac
    14521 ttctcgatgc gctaccagct ggtcgacggc cagggcaact tcggctcggt ggacggcgat
    14581 ccgccggcgg cctatcgcta caccgagtgc cgcatgacgc agcttgcgag cgagctgctc
    14641 gccgatatcg accgcgagac cgtcgatttc gtcgacaact acgacggcaa ggaaaaagag
    14701 ccggtcgtgc tgccgacgcg cgtgccgaac ctgctgatca acggctcggc cggtatcgcg
    14761 gtcggcatgg ccaccaacat tccgccgcac aacctgggcg aagtggtcac ggcctgtatc
    14821 gccctcatcg acgatccgag catcaccatc gcgaccttga tgcagatcat tccgggcccg
    14881 gactttccga ccgccggcat catcaacggc gccgccgaga tcgcctcggc ctatctgacc
    14941 ggccgtggcc gcgtatacgt gcgcgccaag accgacatcg aggaagacga caagggtcgt
    15001 caggccatca tcatcaccga gctgccgtat caggtgaaca aggcgcggct gctcgagcgg
    15061 atcgccgagc tggtgcgcga aaaagtggtc gagggcatcg cctccgatgg cttgcgcgac
    15121 gagtccgaca aggacggcat gcgcgtggtc atcgagctca agcgcggtga agtcgcggat
    15181 gtggtgctga acaaactgtt caagcacacg ccgatggaaa cggtgttcgg catgaacatg
    15241 gtggccttgc aggacggcca gccgaagctg ttcaacctga aggagatgct cgaagcgttc
    15301 gtgcggcacc ggcgcgaagt ggtcacccgc cgcaccgtgt tcgacctgcg caaggctcgc
    15361 gagcgcgccc acattctgga aggccaggcg gtcgcgctgg ccaacatcga tgaagtcatt
    15421 gccttgatca aggcgtcgcc gacgccgcct gaagccaagg tcgcgttgat gagccgcatc
    15481 tggacgtcgg gcgcggtgcc ggcgatgttg gagcgggccg gcgacatcgt ctcccggccg
    15541 gacggcttgt ccatcgagtt cggtctggtc gaaggcggct atcgcttgtc cgacgtccag
    15601 gcgcaagcca tcctggacat gcgcctgaac cggctgaccg gtctggagca ggacaagatc
    15661 atcgccgagt tccaggaact gctgacgcag atcgccgacc tgagcgacat cctggcgcgt
    15721 cccgagcgcc tgttgcaggt gattcgtacc gagctggaag aggtcaaggc caagtacgcc
    15781 gatccgcgtc gcacccagat caatttcgat cattcggatc tgaccatcga agatctgatc
    15841 gaacagcagg acgtggtggt cacgctgtcg catggcggct atgcgaagtc gcagccggtc
    15901 accgattatc aggcgcagcg tcgcggcggt cgcggcaagt ccgccaccgc gatgaaggac
    15961 gaagacttcg tcgacaagct gttcgtcgcc aatactcacg acacgctgtt gtgcttctcc
    16021 agcaccggca agctgtattg gctcaaggtg tatcagctgc cgcaggccag ccggggctcg
    16081 cgcggaaagc caattgtgaa tctgttgccg ctgcaggaag gcgagcgcat caacgcggtg
    16141 ctgcccatcc acgaattcga agaaaacaaa ttcgtgttca tggtcacggc ggcgggcacg
    16201 gtgaagaaga cgtcgctcga agcattctcg cggccgcgcc aggccggcat catcgccatc
    16261 gagctggagc agggcgaccg gctggtcggt gtcgacatca ccgacggcac caagcagatc
    16321 attctgtgct cgagcggcgg caaggccatt cgcttcgatg agaacgacgt gcgtccgatg
    16381 gggcgcacgg cagccggcgt gcgaggcatt cgcttgccgg aaccgacacc agcggctgaa
    16441 ggcgcggagc tgccggccac cgccgccgaa gaggtcatct cgctgatcat cgtcgatgag
    16501 cagggcatgg tgctcaccgc gtccgaaaat ggctacggca agcggaccgc gatcgaggac
    16561 ttcccgatcc atggtcgcgg cggtcagggc gtgatcgcgt tgcaaatcag cgagcgaaat
    16621 ggtcggatgg tcggcgcgct gctggtgaag ccggaagacg agatcatgct gatcagctcg
    16681 ggcggcacgt tggtgcgcac gcaggtcaac gaaatctcgg tgcaaggtcg caacactcag
    16741 ggcgtgcgcc tgatccgggt cgacgaaggc gatcgtctgg tcggtctgga gcgcatcgtc
    16801 agcgaaggtg ctggcgaagc cggcgcggaa ggcgccgagg gtgagggcgg cgaaggcgat
    16861 gccggtggcg acgatggcgg cggcgctgct ccggattctg cctgaccagt cattagtcag
    16921 tagtcattgg ttacttcggg tcttatgcgc gtctataact tcagtcccgg tccggcggtg
    16981 ttgccacagg aagtactcga gcaggcgcgc gaggaaatgc tcgactggca tggcaccggc
    17041 atgtcggtca tggaaatgag ccatcggggc aaggcgttca ttgccatcgc ggaacaggcg
    17101 gaagccgatc tgcgcgagct gctgtcgatc ccgaagaact acaaggtgct gttcctgcag
    17161 ggcggcgcct tcggccagtt cgccggcgtg ccgatgaatc tcagcaagcc cggcgacacg
    17221 gtcgactatg tgaacaccgg cgcctggtcc aagaaagcga tcagcgaggc aaaagcctac
    17281 gccaaggtga atgtggctgc cgatgccggc gagccgtaca cctcgattcc gttgttgtcg
    17341 aattggcagg tgagcgagaa cgccgcctat ctgcactaca cgccgaacga aactatcggt
    17401 ggcgtggagt ttcatttcgt ccccgagctg aagagcggca cgcccctggt cgtcgacatg
    17461 tcctcgacct tgctgtcgcg gcccatcgat gtttccaagt tcgggctgat ctacggtggt
    17521 gcacagaaga acgtcggccc cgccggcctc acgctggtga tagtgcgaga agacctgctc
    17581 ggtcacgccc gtccgggcac gccgtcgttc atggattacg gcgccatggc gaaggaaggc
    17641 tcgatgctga acacgccgcc gacctacgcc tggtatctgg cgggtctggt gttccagtgg
    17701 ttgaagcgcc agggcggcct gaaggccatg ggcgagatca accggcgcaa ggcggagctg
    17761 ctgtactcgg ccatcgatac ctcgtcgttc tataagaatc cggtggcgca cgatgcgcgc
    17821 tcctggatga atgtgccctt cacgctggcg cggccggagc tggacaagac gttcaccagc
    17881 gaggcgaagg acgccgggct ggtgacattg gaaggccatc gctcggtcgg tggcatgcgc
    17941 gccagcatct acaacgccat gccgctggcg ggcgtggaag cgctcgtgag cttcatgaag
    18001 gagttcgagc gcaagcacgc aggatgaagt gactggtgac tgctgaccaa tgactggtca
    18061 gagcgtcgag gggaacgatg tggcttatcg aatcctgatg ctgaacaata tttccgttcg
    18121 cggcctggag cggctgccac gggagagata tgagattgcg tcggcgttga gcaatcccga
    18181 cgccgtgctg gttcgctcgg cggacatgca ctcgatcgag cttcccgcca gcgtcattgc
    18241 cgtcggccgc gccggggcgg gcaccaacaa tattcctgtg tcgcgcctgt ccgcgcgcgg
    18301 cattccagtc ttcaacgcgc cgggcgccaa tgcgaacgcc gtgaaagaac tggtcatcgc
    18361 cggtttattt cttgcggccc gcaatatctg ccaggcctgg gactacgcac gcaatctcaa
    18421 aggctcggat gaagagctgg aggtcgcggt cgagcagggc aagaagaaat acgtcggcta
    18481 cgagctgccc agtcgcacgc tcggtgtcat cggcctcggt gcggttggcg tcgaggttgc
    18541 gaacgcggct catctgcttg gcatgcgagt gctcggtttc gatccgcaaa tcaccgtgca
    18601 acgcgcgtgg caattgtcgt cgggcgtgca gcaggcgttg tcgctggacg atctgttctc
    18661 acgttgcgac atggtcacgg tgcatgttcc cttgatcgaa gcgactcgcg gcttcgtgaa
    18721 cgccgcgcgc atccggctgc tcagagacaa cggcgtcgtg ctcaactttt cacgcgccgg
    18781 catcgtcgat gagaaggcgg tggtggaagc gctcgacagc ggcaagctcg gcgcctacat
    18841 ctgtgacttc ccgaccaacg gcgtgaagca tcatccgaag atcgtggcgc tgccgcatct
    18901 gggcgcgtcc accggcgagg ccgaggagaa ctgcgccatc atggtcgcgg acacgctcaa
    18961 ggacttcctc gagaacggca acatccgtca ctcggtcaat tttcccgagg cggtgctgcc
    19021 ccggaccgcg agctcgaccc ggctgtcgat ctccaacgag aacgtgccga acatggtcgg
    19081 acagatctcc accgccctgg cccacgcccg actcaacatc gccgatctgc tcaacaaatc
    19141 ccgcggcgag ctggcctata cgttgatcga tgtggacggt caggtgcccg ccggggtgct
    19201 ggaccagctg cgcaagatcg agggcgtatt gaacgtgcgt gcgttgtgac cgtcgaggct
    19261 ggcagaatga cgggctgaaa acccgttcag cctcgagcac gactgtctca caatgaagcg
    19321 cactcccaag gccggctctc gcaaggccgt ctccaaaaaa gcggcagcca gaaaggctcc
    19381 ggcgtcggta ccggccgagc tgagctcgat ccgccagcag atcgatgcga tcgatcagca
    19441 catccacgag ttgctgaacg agcgcgcccg ctttgcccag caggtgggcg agtccaagcg
    19501 cggtgagggc atgagcacgg cggactttta caagcccgag cgcgaagcgc aggtgctgcg
    19561 caatgccatc gagcgaaaca aaggcccgct gcgcaacgac gagatcgtgc ggctgttccg
    19621 cgagatcatg tccgcctgtc tggcccagca ggagccgctg aagatcgcgt tcctcggtcc
    19681 ggagggcacg ttctcccaac aggcggtgct gaaacatttc ggccattcgg tgcgggcgct
    19741 gccgctgccg gcgatcagcg aagtattcga ggaagtgcag gccggtcatg ccgacttcgg
    19801 cgtggtgccc atcgagaatt ccaccgaggg gacggtcaat cacacgctgg acatgtttct
    19861 gaattcgccg ctgaagatct gcggcgagat cgagctgcgc attcgtcagc atctgatggg
    19921 ccgcatgaaa gggctgcaga aaatctcgcg tgtctgctca catccgcagt cgctggcgca
    19981 gtgtcggcaa tggctggatg agcatcttcc aaacatcgag cgcgtgccgg tcagtagcaa
    20041 tgccgaggca gcccgccggg cccgcgatga ggacggcacg gcggcgattg ccggcgaggc
    20101 ggcggcggag gtttacaacc tcggcgtgct cgttccggaa atcgaggaca cggccgataa
    20161 caccacgcgc ttcctggtcg tcggtcgcaa gctgttcagc gccagcggcc aggacaaaac
    20221 caccttgcta gtctcggccg gcgacacgca gtcgcccggc gcgctgcatc ggttgctggg
    20281 gccgctggcg gacaacgaca tcaccatgac ccgcatcgaa tcccggccgt cgcgcaaacg
    20341 taaatgggat tatgtgttct tcatcgacgt gatcggccat gccgagcagc cgccgctgtc
    20401 cacggcgctg gatgagctgc gcaaagcgtc cactctgttt cgagtgctgg gctcgtaccc
    20461 ggccgcggtg ctgtaaggcc ggaatgaggg tagactgggc gccctgaggc tcggcgccgc
    20521 cgagccggtg accccgtaaa actagatgtc gcattacata gtcgagcccg tttctggcgt
    20581 ttccggcgcg gtccgcgtgc ccggcgataa gtccgtttca caccgttcgc tcatgctcgg
    20641 cagcatcgcc gatggcgtga ccgaggtgtc cggctttctg gaaagcgaag attgcctgtc
    20701 gaccatgaaa gcgatgcgcg cgctcggcgt gaaaatcgag cagatcggcc cgcaggccgt
    20761 gcgcgttcat ggggtcggca tgcgcggctt gaagccggcg aatcatgcgc tcgacatggg
    20821 caactccggc acgg
//
