LOCUS       NZ_RYEV01000004        22095 bp    DNA     linear   CON 10-DEC-2024
DEFINITION  Peristeroidobacter soli strain JW-3 Scaffold3_1, whole genome
            shotgun sequence.
ACCESSION   NZ_RYEV01000004
VERSION     NZ_RYEV01000004.1
KEYWORDS    WGS; RefSeq.
SOURCE      Peristeroidobacter soli
  ORGANISM  Peristeroidobacter soli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Steroidobacterales; Steroidobacteraceae; Peristeroidobacter.
REFERENCE   1  (bases 1 to 1523009)
  AUTHORS   Huang,J.-W.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-DEC-2018) College of Life Sciences, Nanjing
            Agricultural University, No. 1, Weigang Road, Xuanwu District,
            Nanjing, Jiangsu 210095, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: SOAPdenovo v. 2.04 September-2018
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 174.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004138485.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 18:33:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,689
            CDSs (total)                      :: 7,636
            Genes (coding)                    :: 7,552
            CDSs (with protein)               :: 7,552
            Genes (RNA)                       :: 53
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 19 of 84
            Pseudo Genes (incomplete)         :: 74 of 84
            Pseudo Genes (internal stop)      :: 2 of 84
            Pseudo Genes (multiple problems)  :: 11 of 84
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:27:02
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 475801
            Orig. end                         :: 497896
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            RYEV01000004.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22095
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="redox-cofactor"
                     /region_number="2"
                     /rules="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /tool="antismash"
     cand_cluster    1..22095
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(PF04055 and (TIGR04085 or SPASM))
                     and (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /kind="single"
                     /product="redox-cofactor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22095
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12095](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12095)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
     misc_feature    772..786
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 24.85"
                     /tool="antismash"
     misc_feature    complement(789..802)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 20.11"
                     /tool="antismash"
     misc_feature    complement(1168..1185)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 22.53"
                     /tool="antismash"
     misc_feature    complement(1583..1599)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 18.86"
                     /tool="antismash"
     gene            1652..4144
                     /locus_tag="EKO19_RS17815"
     CDS             1652..4144
                     /GO_component="GO:0009279 - cell outer membrane [Evidence
                     IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1051:
                     TonB-dependent siderophore receptor"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009549971.1"
                     /locus_tag="EKO19_RS17815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TonB-dependent receptor"
                     /protein_id="WP_129777806.1"
                     /transl_table=11
                     /translation="MRIATISTAALSALTLLSTARADEIIDTVTVIGVTPLIGSQIDRS
                     RIAAPVQTATSRQIERSHALDVTAYLNRQIGSVYVNDIQNNALQPDINYRGYTASPLLG
                     TPQGLSVYLDGMRLNQPFGDVVSWDLLPKEALSSMTLIPGSNPVFGSNTLGGALSLQTK
                     DGFSYPGYGVEVNYGSYDRRRIAATAASHGDSGLHWFVTGNDLRDDGWRDDSPTKARQF
                     FGKLGWRNETTDVSLSGSYADTDLTGNGLQDQQLLNQDYESVYTKPDQTKNESYLFNLV
                     LTHKVSDTIALSANAHYRHIETRTFNGDINDDSLGESLYQPNADEREALEEAGYTGFPT
                     SGETQANTPFPFWRCIANALTNEEPNETCNGLANRTRTRQHDAGVSLQAAFTASLGSHS
                     NQFILGMSGLKSNATFEQSSQFGYLLPDRSIQPVDGPGAFADGTQDSENTFDSRVDLDG
                     DTTAYGVYFTDTFELSRLMQLTLSGRYDRTTVDNVDGITDAGEPGSLTARHHFSRFNPA
                     LGVTFNPSEVLSGYIGYSEGSRAPSSIELGCADPENPCRLPNAMAGDPPLDQVVTRTVE
                     AGARGLLAKRLAWNIGVFRADNRDDILFVADDTSGFGYFKNFGKTRRQGVELGVNSQLG
                     PVYVGANYTYLDATYRSPEELLGEGNSSNEEGPGFEGTIEVEPGDRIPLVPRHIFKAFA
                     AWDVTEQISLSLDAINIGSSYARGNENNRHQAEAPYYLGSGEIGGYTVFNLGVEYRPLQ
                     ALTLFAQINNALDREYYTGAQLGSTGFNANGEFVARPFAGPVVDGERPLLGSTFLAPGA
                     PRMFWLGARFAFAGAAKR"
     gene            4370..5422
                     /locus_tag="EKO19_RS17820"
     CDS             4370..5422
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_function="GO:0042802 - identical protein binding
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1029: RND family
                     efflux transporter MFP subunit"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010234547.1"
                     /locus_tag="EKO19_RS17820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="WP_217705425.1"
                     /transl_table=11
                     /translation="MVTAKAQSIENITEVPGRVQAVRTAQVRARVDGIVERRLYEEGTD
                     VKANQTLFVIDPREYRSNVSAVGATLTRAQATAANARQDVERYKGLVKEQAISQQEFDA
                     AMARLRTAEADVAQTQAQLESAKLNLSYTTVSAPIAGRAGRAQVTEGALVSASSATLLT
                     TIEQLEPIYVNFSQSSAYLLAIRREISAGTLKVPELGKVAVTLKLEDGSTYPHAGHLNF
                     LDLSIDQATGTAAVRAEFPNPEQILLPGQFVRARIEAGIRPHGFAIPQRAIQLSSSGAA
                     VLTIAEGDTIAPRPVKLGDQRGDQWIVLDGLHDGDRVVVDGIQKVQPGAHVRVIDADEP
                     AASAAKPAER"
     gene            5426..8578
                     /locus_tag="EKO19_RS17825"
     CDS             5426..8578
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0042908 - xenobiotic transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) RND_efflux"
                     /gene_functions="transport (smcogs) SMCOG1049:
                     AcrB/AcrD/AcrF family protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019340987.1"
                     /locus_tag="EKO19_RS17825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="multidrug efflux RND transporter permease
                     subunit"
                     /protein_id="WP_129777808.1"
                     /transl_table=11
                     /translation="MSPRFFIDRPIFSWVIALGILLAGTLALRSLPIEQYPAIAPPSLT
                     IAVTYPGADAATLETNVTQVIEQELNGVEGFLYMASTSRSNGTASITVTFDSGTDIDVA
                     QMDVQNKLRAIEQRLPEEVRRQGILVNEASSSFLMIVALQSKTGATPSLELGNFAATRV
                     IDELRRVPGVGDIRSFSSEYAMRVWLDPDRLTTYSLSAAEVLAAVQEQNTQSPGGQLGD
                     RPLANRTELNAPILTQNRFTTPEQFASIILRANPDGSTVRVGDVGRVELGAQSYLSDME
                     LNGKPAAGMGIQLSTGANALATATGVKERLTQLQHSFPEDITWAVPYDTTPFISISIDE
                     VVKTLVEAMVLVFLVMFLFLQNWRATLIPTIVVPIALAGACLGLWVLGFSINVLTLFGM
                     VLAIGILVDDAIVVIENVERIMTEEGLPPHEATVKAMTQITSAIIGITLVLVAVFVPMA
                     FFPGSTGGIYRQFSLTLTLSIAFSALLALTLTPALCATLLKSEPLHCRADAERSTSRLG
                     RWSARFFGGFNDWFGRVTHRYQALVGGILARSLRFLAIFVLLVGIALLLFSRLPGSFLP
                     AEDQGAIITVVQAPPGATIDRTDEAIDQVRGFYRAQPQTRSIIFIRGFSFFGQGQSNAM
                     AFVSLTPWDERPGEQNNALTLVGKANALLSQVKQALIFTLNPPSIPSLGVAAGFTFKLQ
                     DRAGLGQQALVNARNQILMAASRSPVLTAVRPEGQADSPQLRVLIDRVKARALGLSIAD
                     VNATLAIAFGSAYANDFSREGRILRVLLQADAPYRMTPADVLALRVRNTQGEMVPFGAF
                     TTTEWTAGPPQTDRYNGYPAMTLSGSPAPGRSSGEAMNEMARLAGQLPEGFDFEWTGIS
                     FEEQQAGGQVGALLGLSLIVVFLLLAALYESWTVPLAVLLVVPLGVLGAVLFTMLRGLP
                     ADVYFNVGLIAIIGLAAKNAILIVEFALEEEAAGKSTFDATMNAVKLRLRPIIMTSLAF
                     ILGMVPLVLSAGAGAASRIAVGTGVMGGMIAATVLGIFFIPVLYLSVRRWLTRGKLKTA
                     HE"
     misc_feature    complement(5469..5484)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.5"
                     /tool="antismash"
     gene            8571..10004
                     /locus_tag="EKO19_RS17830"
     CDS             8571..10004
                     /GO_component="GO:0009279 - cell outer membrane [Evidence
                     IEA]"
                     /GO_function="GO:0015288 - porin activity [Evidence IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1076: RND efflux
                     system, outer membrane lipoprotein,"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010234553.1"
                     /locus_tag="EKO19_RS17830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="efflux transporter outer membrane subunit"
                     /protein_id="WP_217705426.1"
                     /transl_table=11
                     /translation="MSRLSNALRALSIGMFLSACSFAPRDERPALPTAQRYAEGYVDGP
                     AAGTRAVEFGWRDFFADPRLEVLIATALKNNRDLTIAVAQIEEARGLYRVQRSDLLPKI
                     NVNAEVTRNGVGPESAGLTGATPLGTSETFTQYFVGAGVAAFELDFWGRVRNLSRAARA
                     EYLATVEAARAFQLSLIRDVASAYFAALEARERLELAEATVDSRREGLRIAKKRLDAGV
                     TSALDFRQAETLLTQAETELASLRFTKAQNENLLATLVGSAIAEPLPEPLPLADQDRME
                     TLAAGMPSDLLVNRPDILAAEHRLRGARANIGAARAAFFPSITLTGSYGFASTELDSLV
                     GNDRRTWSYGPSISLPIFDFGARRANLTVAEARQNIAIADYERTIQTSFQEVSDALAGR
                     KFLAEQVSAQERGTKAQRQLAELAHRRYNEGVVSYLEVLDAERNLFSAEQALLQVRRAE
                     VSNLVSLYIALGGGQIETR"
     gene            complement(10001..11128)
                     /gene="pqqE"
                     /locus_tag="EKO19_RS17835"
     CDS             complement(10001..11128)
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_process="GO:0018149 - peptide cross-linking [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: SPASM"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018974288.1"
                     /locus_tag="EKO19_RS17835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqE"
                     /protein_id="WP_129777809.1"
                     /sec_met_domain="PF04055 (E-value: 7.7e-24, bitscore: 81.1,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 2.4e-10, bitscore: 36.9,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAAVTTSPSVGPPLWLLLELTYRCPLQCVFCYNPIDFAKVEDEL
                     TTGEWLRVLREARALGSVQLGLSGGEPLVRDDVEQIAAEAHRLGYYTNLITSGVGLSRE
                     RLSELKRVGLDHIQLSFQDSTREMNDFLSHTRTFELKKRCAEWIKSHGYPMVVNCVIHR
                     LNIDHLDTIIDMAVQMGADYLELANTQYYSWAHLNREHLLPSREQLQRAERTMLEWRER
                     MKGKMRILFVVPDYYEQRPKRCVNGWGTTLATIAPDGTALPCHTARMLPGLSFPNVRTK
                     GMREIWFQSEAFNKFRGFGWMKEPCASCEEREKDLGGCRCQAYLLAHDPAVADPVCSKS
                     PHHQVVLAALDRAQQPQVPEAPLIFRRRENSSRLA"
     gene            complement(11125..11397)
                     /gene="pqqD"
                     /locus_tag="EKO19_RS17840"
     CDS             complement(11125..11397)
                     /GO_function="GO:0048038 - quinone binding [Evidence IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009239165.1"
                     /locus_tag="EKO19_RS17840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pyrroloquinoline quinone biosynthesis peptide
                     chaperone PqqD"
                     /protein_id="WP_129777810.1"
                     /sec_met_domain="PqqD_RRE (E-value: 5.4e-28, bitscore:
                     92.8, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 9.7e-17, bitscore: 57.2,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQADRPSMRPGFRLQWEEVQKAYVLLYPEGMVKLNTSAAEILRR
                     CDGERSVDEIVADLESAFNRKGLQGDIEQFLQLARAQGWLSAAVS"
     aSDomain        complement(11140..11394)
                     /aSDomain="PqqD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing protein in a pyrroloquinoline
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_EKO19_RS17840_PqqD_RRE.1"
                     /evalue="1.30E-29"
                     /identifier="RREFam006.1"
                     /label="EKO19_RS17840"
                     /locus_tag="EKO19_RS17840"
                     /protein_end="86"
                     /protein_start="1"
                     /score="92.8"
                     /tool="antismash"
                     /translation="TQADRPSMRPGFRLQWEEVQKAYVLLYPEGMVKLNTSAAEILRRC
                     DGERSVDEIVADLESAFNRKGLQGDIEQFLQLARAQGWLS"
     gene            complement(11394..12095)
                     /gene="pqqC"
                     /locus_tag="EKO19_RS17845"
     CDS             complement(11394..12095)
                     /EC_number="1.3.3.11"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR02111"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008059649.1"
                     /locus_tag="EKO19_RS17845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pyrroloquinoline-quinone synthase PqqC"
                     /protein_id="WP_129777811.1"
                     /sec_met_domain="TIGR02111 (E-value: 3.2e-103, bitscore:
                     340.3, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGDVPWNEAEFELHLREQGQAYHIHHPFNVMLNTGKASRQQIQG
                     WVANRFYYQISIPRKDAAILANCPDREVRRRWVERILDHDGHGDDPGGIEAWLRLAEAV
                     GLERAEVEELQWLIPGVRFAVDAYVNFARQAPWQEAVCSSLTELFAPAIHRQRLSSWPE
                     HYPWIEQDGLQYFRSRVSLAQRDVNHGLAVTLACFKTREQQQRALQVLKFKLDILWAMN
                     DAMAQHYGVQS"
     gene            complement(12092..12997)
                     /gene="pqqB"
                     /locus_tag="EKO19_RS17850"
     CDS             complement(12092..12997)
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008059648.1"
                     /locus_tag="EKO19_RS17850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqB"
                     /protein_id="WP_129777812.1"
                     /transl_table=11
                     /translation="MHIRILGAAAGGGFPQWNCNCPNCGGVRREELDARPRTQSSIAIR
                     GADETAWTLVNASPDILAQLQANPQLQPGRAYRDTGIRNIVLTDSQIDHTTGLLMLREA
                     TRPWPLWCTDNAFADLTISNPILQVLQRYCGIDRQRIVTGEWFTVEGSDDLRWQAIALP
                     GRPPPYSTRAPALGDVIGLIVEDVRTEARLCYAPGVANIDSWLFELMSSAQCVLVDGTF
                     WTDDELVRLGVSHKRAADMGHLSQTGGMITWLDRLPATTRRVLIHINNTNPILVEDSPE
                     RALLSERRIEVAYDGMEIVL"
     gene            complement(13050..13124)
                     /gene="pqqA"
                     /locus_tag="EKO19_RS39895"
     CDS             complement(13050..13124)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqA"
                     /inference="COORDINATES: protein motif:HMM:TIGR02107.1"
                     /locus_tag="EKO19_RS39895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pyrroloquinoline quinone precursor peptide PqqA"
                     /protein_id="WP_129778511.1"
                     /transl_table=11
                     /translation="MTWETPVAIDLRLGMEITMYAEHR"
     misc_feature    complement(13193..13207)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.38"
                     /tool="antismash"
     gene            13279..14625
                     /locus_tag="EKO19_RS17860"
     CDS             13279..14625
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.5"
                     /locus_tag="EKO19_RS17860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /protein_id="WP_129777813.1"
                     /transl_table=11
                     /translation="MKLRTHVNLIVASLSAAFVILAAWLQFDGTRRAVREEIAGANVVA
                     TQLLSRILIGYDQRDDEQLLTFLQHLGRVRAHEITVRDANRQIIYESPPSPYKAGREAP
                     AWYASFILPTTPVHIFPLANGSEVRIEANASRAILDGWDDFKHLMMVGGIAFAILNAAV
                     FWLVGRAVAPWPIIVEGLTRIEQGDLRHRLPKLKGYEANMIGSTFNRMAVSLEEKLLSD
                     RKAVEAEQRLQQRRELDQLIEQRLDEERRVIARELHDEFAQSVTAIRSFAVVIANQHPV
                     DSQTAEVARLISSEAAQLYDAMHGLIPRLAPLTLDTLGLAETLEGFIKQWQGRHPAIRF
                     SLHHELPTELGTSATIAVYRVVQEAVINAVRHARPTQVEVSVVHSDSHIRVRVTDNGIG
                     LPEDWSRPGHFGLRGLQERMAMLGGTLTLKNREPGGVALTAEIPLGEHA"
     gene            14622..15251
                     /locus_tag="EKO19_RS17865"
     CDS             14622..15251
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012345279.1"
                     /locus_tag="EKO19_RS17865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_129777814.1"
                     /transl_table=11
                     /translation="MIRVLLVDDHTVVRTGFRLLLETVSDVRVIAEADSGETACVRFDE
                     DKPDVVVLDLSMPGMGGLETLRRLRARDKEVKTLALSAHDDAIHARRALKQGALGFLSK
                     RTAPETLLEAVRMVAAGQRYIDPKLAQEIALAEVGGATLVDALSEREFEVFLRLANGAA
                     VPKIAAELNLSTSTVGTHLYNIKQKLHAGNQAELTLIALRAGLIER"
     misc_feature    15257..15271
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.38"
                     /tool="antismash"
     gene            15462..>16097
                     /locus_tag="EKO19_RS39530"
                     /pseudo=""
     CDS             15462..>16097
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019335.5"
                     /locus_tag="EKO19_RS39530"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="TonB-dependent receptor plug domain-containing
                     protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MCGITITVPADLARNRLSEPLKGERCGEVALQRLLQGSGLSYKKA
                     PDGGIAIVAIAPSLRTAAAVTPAPRRLAAAAAPAPAPQTKADDAPILEEVTVTAGKRGE
                     ERLQDVPVSITALTQETIVQAGMDNFLDYARSVPGVGFKITSPAGGRDDLRGGRRVNIR
                     GIESGFDSVPTTAFYLDEAPVPVMDPKLFDVERIEVLRGPQGTLYGANS"
     misc_feature    16140..16153
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 16.24"
                     /tool="antismash"
     gene            16325..16924
                     /locus_tag="EKO19_RS39200"
     CDS             16325..16924
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012801.5"
                     /locus_tag="EKO19_RS39200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TonB-dependent receptor"
                     /protein_id="WP_246038932.1"
                     /transl_table=11
                     /translation="MADRRVRLNTSAYFIDWKDVQKTVQMFNCGFSFIGNIGAAESKGA
                     EIELAATPINGLDIGASAGYTDAQYTKSSVEAGVMAGDPFPIVPQWTASASVQYRFPII
                     GGRSAHVRADAQYVDKSISDFFSHDGLPVVQPSYELVNMRFGMDLTERLAVTVSVDNVF
                     DERPVLDTVDYGPPYGFITSTSRPRTFGLTFRYSGR"
     gene            17022..18317
                     /locus_tag="EKO19_RS17880"
     CDS             17022..18317
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009770693.1"
                     /locus_tag="EKO19_RS17880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF3300 domain-containing protein"
                     /protein_id="WP_129777817.1"
                     /transl_table=11
                     /translation="MNRSLRLCSSLLASLLALVQPAAHSQQTPPQPTTPSAEDQAKAQP
                     FKPEELEQIVAPIALYPDALLAQVLMASTYPLEIVLAARWSADHPDVKGDAVAKAVENE
                     TWDASVKSMVAFPDVLKMMNEKLDWTQKLGDAVLAQRKDVMDAVQRLRVKAKDAGNLKS
                     GKEQTVKTEAAPAGSTAPQVIIIESPSPEVVYVPTYNPTVVYGAWPYPAYPPYYYYPPG
                     YAAGAAFFTFSAGVIVGGALWGGFNWGHSDIDINVNRYNNFNRTNINNVNRTNVSNRWE
                     HNSAHRQGVGYRDSATQQRYGRGSSPQALQARENYRGRDLNNGQLGTGGQQNRDLGANE
                     SRDLGGRTNENRNLGGGGENRDLGNRGNEYRDLGGGAENRDLGSASRDFDRGGGGSSDA
                     FRGVDSGASTRAHSSRGAASRGGMSRGGGRRR"
     gene            18314..19339
                     /locus_tag="EKO19_RS17885"
     CDS             18314..19339
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009798069.1"
                     /locus_tag="EKO19_RS17885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF2950 domain-containing protein"
                     /protein_id="WP_129777818.1"
                     /transl_table=11
                     /translation="MKQQISSTLRIFMLLLMMAAAACNRGTQRDFASIDDAVGALVAAA
                     RSDDTRALVKVLGAEAEPAISSGDPIQDRNARERFVRAYETEHTLSRGAAGEATLLVGT
                     DQWPFPFPLVQSNGRWHFDSDAGTDEIVNRRVGANELATIQSCLAFVDAQREYYMRNPQ
                     GAALLQFSQRLVSSKGQKDGLYWPTTGNEPPSPLGEGFARAQGEGYFQNGPSKNEPLRG
                     YIYRLLTAQGPNARGGAYSYLVDGKMIGGFALITIPAEYGRSGVMTFIVNHDGVVYSKD
                     LGPDTPTAARAIQTFDPDSSWQPEVATGQPMAAQIAPAVVQFLGEAGFDHERDILMGIL
                     R"
     gene            19398..19724
                     /locus_tag="EKO19_RS17890"
     CDS             19398..19724
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKO19_RS17890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_129777819.1"
                     /transl_table=11
                     /translation="MPAVSPAPAPLQSGYIVARYGDIRIHSFCVGWAYPTLFLTVNGND
                     SIMSTERPNNVIALAPYRFAHQASQRRSRPYVTWYPNVGFVAPTPNTLAPIRQLRTARG
                     PESM"
     gene            complement(19810..20388)
                     /locus_tag="EKO19_RS17895"
     CDS             complement(19810..20388)
                     /EC_number="1.11.1.24"
                     /GO_function="GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1196: alkyl hydroperoxide reductase/ Thiol specific"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020481380.1"
                     /locus_tag="EKO19_RS17895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="peroxiredoxin"
                     /protein_id="WP_129777820.1"
                     /transl_table=11
                     /translation="MKTQGLLLTGLLGLTALPALAALQEGAPAPEFTAQASLAGKPFTY
                     SLKDALKKGPVVVYFYPSAYTGGCNVQARTFAVNKDKFAAAGASIIGVSLDSIERLNDF
                     SKDPEYCAGKFPTASDVDGKIAKSYELQVREAGTGKKDTRGQDIDHGFAERTTFIVTPD
                     GKVAATVGGLNPVENVNKSLEIVQKLKGG"
     gene            complement(20513..21628)
                     /locus_tag="EKO19_RS17900"
     CDS             complement(20513..21628)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018748336.1"
                     /locus_tag="EKO19_RS17900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_217705428.1"
                     /transl_table=11
                     /translation="MLLPTAFTATEAMMRLAKTVAAAVLLLATALSAIAAVPPSYPRSY
                     ANRIADANEDGRLSIYSTTDAREVAQLLQDFRSLYPRIRVEYFDINSTELYNRFIAEVA
                     AKEASADLLWSSAMDLQIKLVNDGYAQAYASPEKPNLPAWAIWKNEAYGTTAEPVVLVY
                     NKRLVPAAEVPHTRADLERLLTDNPSYVGKVAMMDPERSGAGFLYMTQDLRVTRDNWRL
                     VHAMGRAKVQFYSSTGAMLERVASGEHLLAYNTIGPYALERAARDPAIGVILPSDYTLV
                     ASRIALIPADARHPDAAKLFLDYLLSRRGQAFLAQKHMTPVRSDVDAPPGTHIDAPNMR
                     AIRVGPELLANLDQIKRLRFLKDWRNAVNQD"
     misc_feature    21759..21772
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.81"
                     /tool="antismash"
ORIGIN
        1 gcaggcctga tggtgggcgc ggattggagc gagcgcgaag aaggcaccaa cggcatcggc
       61 acctgcatcg ccgagaatcg cccggtgatc gtgtatcgcg aagaacactt tcgcgcgtgt
      121 cacatcggtc tgtcgtgctc gggcgcgccg attcgcgatc cctccggccg actgctcgcc
      181 gttctcgatg catccacatt gaacgcacgc gacacgcgcg cgagcctggc gcacaccatg
      241 gcgctggtga gcctgtcggc gcagctgatc gagaaatgtc tgttcctgca acagttccag
      301 accgagaacg tgttccgctt ccacgcgcgt ccggagttcg tgaatcttca gcacagcggc
      361 gtgatcgcgg tctcgcatgc cggcaaagtg gtcgcggtcg atgaaacggc gctgtggctg
      421 ctgcgcgcga ggagtcgcga cacgctggtg ggtcgcggca tcgatgaaat cttcgaggtg
      481 aatgcgtcgg agctgatcga accggccttc cgcacccagc tgtcgttacg cccggtgcgc
      541 gacctgctgt tcggccgcca cttctttctc agtctggatc aggatgcggg cacgacgact
      601 cgctcgctgg ccggcccagc gccgtcgcgg gagattctgc agctgtcgtc caccatcacc
      661 cgcaagcccg tgctctcgct cgaagatctg gccggtgacg atccgcagat ggcacgcaat
      721 ataaggagtg cccggcgcat cgcgaactca cgcgtgccgg tcatgattca agggccgacc
      781 ggcgccggca aagagatgtt tgcacgcgct ttgcatgctg cgagtgatcg agccgcgcgc
      841 gccttcgtgg ccctgaactg cgccgccatt cccgagacgc tcatcgagag cgaattgttc
      901 gggtacgcgg ccggcgcatt caccggggcc cgcaagggag gcatgaaggg caagatcctg
      961 cagtcctccg gaggcacgct gttcctcgac gagatcggcg acatgcagct gagcttgcag
     1021 acccgcctgt tgcgcgttct ggaggaacaa gaggtcatgc cgttgggaac ggagacgccg
     1081 atcaaagtcg acctgcgcgt gatgtgcgct tcgcatcaga acctgcgggc catgatcgcg
     1141 cgcggcgcct ttcgcgagga tctctactat cggctcaacg gcatcaccat cgagctccca
     1201 cccctcgcgc agcgtaccga taaggaacga ttgatccgcg agttcttcgc caccgaaagc
     1261 ggtgatggcc ggccggtcgc gatcgagctg gatgcgttcc agcggctgct cgattacagc
     1321 tggcccggca acgtgcgcga gctgcgtaac gtgatccgga ccattctcgc gatctgtgac
     1381 agcgacgtga tccgcatggt cgacctgccc agcgaggtac ggctgtgtca gagccgctgc
     1441 gacgacgcga gcgaggttgc accgtccatc gaacgcgagg aactcgttca atgcatccgt
     1501 gactgcgacg gcaacatgtc gcgggcggcc gaaaagctcg gtgtgagcag aaacacgctg
     1561 taccgccgct gcaagcgtct ggatgttcca ttacagcact cgcgcggaat catctaaacc
     1621 aacaatacca gggacggcaa ggagtccggg gatgcgtatc gccacgatca gcacggccgc
     1681 gctgtctgcg ctcacgctat tgagcacggc gcgtgcggac gagatcatcg atacagtaac
     1741 ggtcatcggc gtcaccccgc tgatcggctc gcaaattgac cgcagccgga tcgcagcgcc
     1801 cgttcaaacc gcgacctctc gccagatcga gcgctcgcac gcgctggatg tcaccgccta
     1861 tctgaaccgg cagatcggca gtgtctacgt caacgatatc cagaacaacg cgctgcagcc
     1921 ggatatcaac tatcgcggtt acaccgcctc gccgttgctc ggcacgccgc agggactctc
     1981 tgtttatctc gacggcatgc gactcaacca gccgttcggc gatgtggtga gctgggacct
     2041 gctgcccaag gaggcgctgt cgtcgatgac cctgattccc ggatccaatc cggtgttcgg
     2101 ctccaacacg ctgggcggcg cgctgtcgct gcagaccaag gacggcttca gctatccggg
     2161 ctatggcgtc gaggtcaatt acggctcgta tgatcgccgc cggatcgcgg cgaccgccgc
     2221 atctcacggc gacagcggcc tgcattggtt cgtcaccggc aacgacctcc gcgacgacgg
     2281 ctggcgcgac gattcgccga ccaaagcacg ccaattcttc ggcaagctcg gctggcgcaa
     2341 cgaaaccacc gatgtttcgc tgagcggctc gtatgcggat accgacctga ccggcaatgg
     2401 cctgcaggac cagcagttgc tgaatcagga ctacgagagc gtctacacca aacccgacca
     2461 gaccaagaac gagtcgtacc tgttcaatct ggtgctgact cacaaagtca gcgacacgat
     2521 cgcgctgtcc gccaacgcgc actaccgaca catcgaaacc cgcaccttca acggcgacat
     2581 caacgacgac tcgctgggcg aatcgttgta tcaaccgaac gccgacgagc gggaggcgct
     2641 cgaggaagcg ggctacaccg gcttcccgac cagcggcgag acccaggcaa acacgccctt
     2701 cccgttctgg cgctgtatcg ccaacgcgct caccaacgag gagccgaacg agacgtgcaa
     2761 tggcctcgcc aaccggactc gcacccggca gcatgacgcc ggcgtgtcgc tgcaagcggc
     2821 cttcacggcc tccctcggat ctcacagcaa tcagttcatc ctcggcatgt ccgggttgaa
     2881 gagcaacgcg acgttcgaac aatcttcgca gttcggctat ctgctgcctg accggagcat
     2941 tcaacccgtg gacggccccg gcgcctttgc cgatggcacc caggattccg agaatacctt
     3001 cgactcccgc gtcgatctcg atggcgacac gaccgcctac ggcgtgtact tcaccgatac
     3061 attcgagctg tcgcgcctga tgcaactcac gctgtcgggc cgctacgacc gcaccaccgt
     3121 cgacaatgtc gatggcatca ccgacgccgg cgagcccggc tcgctcaccg ccagacatca
     3181 cttcagccgc ttcaatccgg cgctcggagt gacgttcaat cccagtgaag tgctgtcggg
     3241 ttacatcggc tatagcgaag gcagtcgcgc cccctcctcg atcgagctgg gctgcgccga
     3301 tcctgagaat ccctgccgct tgcccaacgc gatggcgggc gacccgccgc tcgatcaagt
     3361 cgtcacccgt accgtcgaag ccggcgcgcg cggtctgctg gccaagcggc tcgcctggaa
     3421 catcggtgtg ttccgcgccg acaaccgcga cgacattctc ttcgtcgccg acgacacctc
     3481 cggctttggc tacttcaaga acttcggcaa aacccgccgc cagggcgtcg agctcggcgt
     3541 caacagccag ctcgggccgg tgtatgtggg cgccaactac acttatctgg atgcgaccta
     3601 tcgcagcccc gaggaactgc tcggtgaggg caacagcagt aacgaagaag gtcccggctt
     3661 cgaaggcacc atcgaggtcg aacccggcga tcgcattccc ctggtcccac gacacatctt
     3721 caaagcattc gccgcctggg atgtgacgga gcagatctca ctcagtctcg atgccatcaa
     3781 catcggcagc tcctatgcgc gtggcaacga gaacaaccgg caccaggccg aggcgcccta
     3841 ttatctcggg tccggagaga ttggtggcta tacggttttc aacctgggcg tggaatatcg
     3901 ccccctgcag gcgctgacgc tgtttgcaca gatcaacaat gcgttggacc gggagtacta
     3961 cacgggcgcg caactcggct cgaccggatt caacgcgaac ggagaatttg tagctcgacc
     4021 cttcgcaggc ccggtcgtcg atggcgaacg accgctattg ggctcgacgt tccttgcgcc
     4081 cggcgcgccg cgcatgttct ggctgggcgc gcgattcgcg ttcgctggcg ctgcgaaacg
     4141 ctgaacgaca gcgaccctgc acttgttact taccatcttc catattgtgt ttctttgttg
     4201 ctggcgctat acgaacccgg tcacaaacaa tctcgcggca gggaggccat ggcgttgagt
     4261 aacaaatctc atgctgcagc tggccagagg cggcggcgcc ctttgcttgg tgttgctgtg
     4321 ttcttgcact agcaaggcgc cccccgcgcc gccaccgccc gaagtgcggg tggtcaccgc
     4381 gaaagcgcaa tccatcgaaa acatcaccga agttcctggc cgcgtgcagg ccgttcgcac
     4441 cgcgcaggtg cgcgcccgcg tggacggcat cgtcgagcgc cggctttatg aggaaggcac
     4501 cgacgtcaaa gcgaatcaga cgttgttcgt aatcgaccct cgtgagtatc gatccaacgt
     4561 gagcgccgtc ggcgccacgc tgacgcgcgc tcaggccacc gcggctaatg ctcgacagga
     4621 tgtcgagcgt tacaaaggcc tggtcaagga acaagcgatc agtcagcagg aattcgacgc
     4681 ggcgatggca cgcttgcgca ccgctgaagc ggacgtggcg caaacgcaag cacaactcga
     4741 aagcgcgaag ctcaacctga gctacacgac cgtgagcgcg ccgatcgccg gtcgcgccgg
     4801 acgcgctcag gtcaccgaag gcgctctggt cagcgcctcc tcggcgaccc tgctcaccac
     4861 catcgaacag ctcgaaccga tctatgtgaa tttctcgcag tcgagcgctt atctgctggc
     4921 cataagacgt gaaatctcag ccggcacgct caaggtgccc gagttgggca aagtcgcggt
     4981 cacgctgaag ctcgaggacg gcagcactta tccgcatgcc ggtcatctga actttctgga
     5041 tctgtccatc gatcaggcga ccggcaccgc ggcggtccgc gcagagtttc cgaatccgga
     5101 gcagatattg ctgccagggc agttcgtgcg cgcacgcatc gaggccggca tccggccgca
     5161 tggatttgcg attcctcagc gtgccattca actgagctcg tcgggagccg cggtattgac
     5221 catcgccgag ggcgacacga tcgcgccccg gcccgtgaag ctcggcgatc agcgcggcga
     5281 tcaatggatc gtgctggacg ggctccacga tggagatcgt gtggtcgtgg atggcattca
     5341 gaaagttcag cccggcgcgc acgttcgcgt gatcgacgcg gacgagcccg ctgcaagcgc
     5401 cgccaaaccc gcggagcgct gaggcgtgtc gccgcgcttc ttcatcgatc gcccgatttt
     5461 ctcctgggtg atcgcgctcg gcattctgct cgccggcacg ctggccttgc ggtcactgcc
     5521 gatcgagcag tatcccgcca tcgccccacc ctccttgacc atcgcggtca cctatcccgg
     5581 cgcggatgcc gcgacgctcg aaaccaacgt cacgcaggtc atcgagcagg aattgaacgg
     5641 cgtcgaaggc tttttatata tggcctcgac cagccgctcg aacggcaccg cgtcgatcac
     5701 cgtgaccttc gactcgggca cggacatcga tgtcgcgcaa atggacgtgc agaacaaact
     5761 gcgtgccatc gagcagcggc tgcccgaaga ggtgcgccgt caaggcatcc tggtgaacga
     5821 ggcgtcgtcg agctttttga tgatcgtggc gctgcagtcg aaaacggggg cgacgccttc
     5881 gctcgagctc ggcaacttcg cggccacccg cgtgatcgac gagctgcgcc gcgtgcccgg
     5941 cgtcggcgac attcgttcgt tctcttccga gtacgcgatg cgcgtgtggc tcgatccgga
     6001 ccgcctcacg acctacagcc tgtcggccgc cgaagtgctg gcggcggtcc aggaacagaa
     6061 cacgcagtcc cccggtggcc agctcggcga ccggccgctc gccaaccgga ccgagctgaa
     6121 cgcccccatc ctcacccaga accggttcac gacgcccgag caatttgcat cgatcatcct
     6181 gcgcgccaac cccgacggct cgaccgtgcg agtgggcgat gtgggtcgag tcgagctggg
     6241 agcgcaaagc tatctttccg acatggagct gaacggcaag ccggccgcag gcatgggcat
     6301 ccagctttcg accggcgcca atgcgctcgc gaccgcgacc ggcgtcaagg agcgcctgac
     6361 acaactccag cactcctttc cggaggacat cacctgggcc gtgccatacg acaccacccc
     6421 cttcatcagc atctcgatcg atgaggtggt gaagacgctc gtcgaagcca tggtgctggt
     6481 gttcctggtg atgtttctgt ttctacagaa ctggcgcgcc accctgattc ccaccatcgt
     6541 cgtgccgatc gcgctggccg gcgcctgtct gggattgtgg gtgctcggct tctccatcaa
     6601 cgtgctgacc ttgttcggca tggtgctcgc catcggcatt ctggtcgacg atgccatcgt
     6661 ggtgatcgag aacgtcgagc gcatcatgac ggaggaaggt ctgccgccgc atgaggcgac
     6721 cgtgaaggcg atgacgcaga tcacctccgc aatcatcggc atcacgctgg tgctggtcgc
     6781 ggtgttcgtg ccgatggcgt tttttccggg ctcgacgggc ggtatctacc ggcaattctc
     6841 actgacgctc accttgtcga ttgcgttctc cgcgttgctc gcgctcacgc tgacccctgc
     6901 actgtgtgcg accctgctca agtccgagcc cctgcattgc cgtgcggatg ccgagcgatc
     6961 caccagccgg ctgggccgct ggtccgcgcg cttcttcggc ggcttcaacg actggttcgg
     7021 tcgggtgacg catcgctatc aggcgctggt cggcggcatc ctcgccagat cgctgcgctt
     7081 cctcgccatc ttcgtattgc tggtgggcat cgcgctgctg ctgttctcac gcctgcccgg
     7141 cagctttctg ccggccgaag atcagggcgc gatcatcacc gtcgtgcaag caccgccggg
     7201 cgccacgatc gatcgcaccg acgaggccat cgaccaggtc cgaggtttct atcgcgccca
     7261 accacaaacc cgaagcatca tcttcatccg aggcttcagt ttcttcggcc agggtcagtc
     7321 gaacgccatg gcctttgttt cgctcacccc ctgggatgag cgtcccggcg aacagaacaa
     7381 cgcgctaacc ctcgtcggca aggccaacgc cctgctctcg caagtgaaac aggcgctgat
     7441 atttacgctc aacccgccat cgattccgtc gctcggcgtc gccgcgggct tcacgttcaa
     7501 gctgcaggat cgcgccggtc tcggacagca ggcgctggtc aacgcgcgca atcaaatcct
     7561 gatggccgcg agtcgaagcc cggtgctcac ggcggttcga ccggagggtc aggcggactc
     7621 gccgcagctg cgcgtgctca tcgatcgggt caaggcccga gccttgggac tgtcgatcgc
     7681 cgacgtgaac gcgacactcg ccatcgcctt tggcagtgcg tacgccaacg acttcagtcg
     7741 cgaggggcgc atcctgcgcg tgctgttaca agccgacgct ccgtatcgaa tgacacccgc
     7801 ggacgtgctc gcgctcagag taaggaacac gcaaggagag atggtgccat tcggggcgtt
     7861 cacgaccacc gagtggactg ccggtccgcc acaaacggat cgctacaacg gctatccggc
     7921 gatgaccctc tcaggctcgc ccgcccccgg tcgctccagc ggcgaggcga tgaacgaaat
     7981 ggcacgactc gcggggcagc tgccggaagg gttcgatttc gaatggaccg gcatttcttt
     8041 cgaggagcaa caggccggcg gccaggtggg cgccttgctg ggcctgtcgc tgatcgtcgt
     8101 gttcctgttg ctcgccgcct tgtatgaaag ctggacggtg ccgctcgcgg tgttgctggt
     8161 cgtgccgctc ggcgtgctgg gcgcggtgct gtttacgatg ctccgggggt tgcccgcgga
     8221 tgtctatttc aacgtcgggt tgatcgcgat catcggcctc gccgccaaga acgccattct
     8281 gatcgtggag ttcgcgctgg aagaagaagc ggcaggtaaa tccaccttcg atgccaccat
     8341 gaacgcggtg aaactgcgcc tgcgccccat catcatgacc tcgctcgcgt tcatcctggg
     8401 catggtgcct ctggtactgt cggccggcgc gggcgcggcc agtcgtatcg cggtgggcac
     8461 gggcgtcatg ggcggcatga tcgccgcaac cgtgctgggc atcttcttca tcccggtgct
     8521 ttacctgtcc gtgcgacgct ggttgacgcg cggaaagttg aagacagccc atgagtaggc
     8581 tctccaacgc actgcgcgcc ctcagcatcg gaatgtttct ttccgcgtgc tcgttcgcac
     8641 ctcgcgacga gcgccctgcg ctaccgactg cgcagcgata tgcggaaggc tacgtcgacg
     8701 gtcccgcagc cggcacacga gccgtcgaat tcggatggcg agatttcttt gccgacccac
     8761 ggctggaagt cttgatcgcg acggcgctga aaaacaatcg cgacctgacg atcgcggtcg
     8821 cgcagatcga agaagcgcgc ggcctgtatc gcgtccaacg atccgatctg ctaccgaaga
     8881 tcaacgtcaa cgcagaagtc acgcgcaacg gcgtcggtcc ggagagcgcc gggctcacgg
     8941 gggcgacacc gctgggcacc agcgagacgt tcacccagta cttcgtgggc gcgggtgtcg
     9001 ccgccttcga gctggatttc tggggtcgcg ttcgcaatct atctcgggcc gcgcgcgccg
     9061 agtatctcgc gaccgtcgag gcggcccggg cgtttcaact ttcgctgatt cgggacgtcg
     9121 cctccgcata tttcgcagcg ctcgaagccc gcgagcgcct ggaattggcg gaagccaccg
     9181 tcgacagtcg tcgcgaaggc ctgcgtatcg caaagaagcg cctggatgcc ggtgtcacgt
     9241 ccgctctgga tttccgccag gctgaaacgc tgctgacgca ggcagaaacc gagcttgcat
     9301 cattacgctt caccaaggca cagaacgaga acctgctcgc gaccctcgtc ggcagcgcca
     9361 tcgccgaacc gctgcccgag ccattgccgc tcgcggacca ggaccgaatg gaaacattgg
     9421 ccgcggggat gccatcggat ttgttggtaa accgacccga cattctggcc gctgagcatc
     9481 ggctgcgtgg cgctcgcgcg aacatcggcg cggcgcgcgc ggcattcttt ccttcgatca
     9541 ccctgaccgg cagctacggc ttcgcgtcga cggagctgga ctcgctggtc ggcaacgatc
     9601 gacgcacctg gtcctacggg ccgtcgatct cgctgccgat cttcgacttt ggcgcccgcc
     9661 gcgccaacct gaccgtcgcc gaggcgcgcc agaacatcgc gatcgccgac tacgagcgca
     9721 ccattcaaac cagctttcag gaagtctcgg acgcgctcgc cggtcgcaag tttcttgccg
     9781 agcaagtgag tgcccaggag cggggaacga aggcacaacg acaactcgcg gagctcgcgc
     9841 atcgccgtta taacgaaggc gtcgtcagct acctcgaggt gctggatgcg gagcgcaatc
     9901 tgttctcagc ggagcaggca ctgctgcagg tccgtcgcgc cgaggtgtcc aatctcgtgt
     9961 ctctgtatat cgcgctgggt ggcggacaga tcgagacgcg ctaggcgaga cgactggaat
    10021 tctcgcgacg cctgaagatc aacggcgcct cgggcacctg cggctgctgc gcccggtcga
    10081 gcgccgccag gaccacctga tgatgcggac tcttggagca caccggatcc gccaccgccg
    10141 ggtcatgggc cagcaaatac gcctgacacc gacacccgcc cagatccttc tcccgctcct
    10201 cacaactcgc gcacggctct ttcatccagc caaagccgcg aaacttgttg aacgcctcgg
    10261 actgaaacca gatctcccgc atgcccttcg tgcgaacatt cggaaagctc aaccccggca
    10321 gcatcctcgc cgtgtgacac ggcagcgccg tcccgtccgg cgcgatggtc gcaagcgtcg
    10381 tgccccagcc attcacacat cgcttcgggc gctgctcgta gtaatccggc accacgaaca
    10441 gaatccgcat cttgcctttc atccgctcgc gccactcgag catcgtccgc tcggctctct
    10501 gcaactgctc tcgcgacggc agcaggtgct cccgattcag atgggcccac gagtaatact
    10561 gcgtgttcgc cagctccaga tagtccgcgc ccatttgcac cgccatgtcg atgatggtgt
    10621 cgagatgatc gatgttgagc cgatggatca cgcagttgac caccatcgga tagccgtgcg
    10681 acttgatcca ctccgcgcag cgcttcttca gctcgaacgt tctggtgtgc gacaggaaat
    10741 cattcatctc ccgggtcgag tcctgaaacg acagctggat gtgatccagc cccacccgtt
    10801 tcaactcact caagcgctcg cgcgacaaac cgacgcccga tgtaatcaga ttcgtgtagt
    10861 accccaaccg atgcgcctcg gccgcgatct gctcgacgtc atcccgcacc aacggctcgc
    10921 cacccgacaa tcccaattgc accgacccga gcgcccgcgc ctcgcgcagc actcgcagcc
    10981 attccccggt cgtcaactca tcctcgacct tggcgaagtc gatcgggttg taacagaaca
    11041 cacattgcaa cggacatcga tacgtcagct cgagcagcag ccacaagggc ggcccgacag
    11101 acggcgatgt tgtcactgcc gctttcatga caccgccgca ctgagccagc cttgcgctct
    11161 ggccagctgc aggaattgtt cgatgtcgcc ttgcagcccc ttgcgattga acgccgactc
    11221 caggtccgcc acgatctcat cgacactgcg ctcgccatcg caccgacgca gaatctccgc
    11281 ggcactggtg ttcaacttca ccatgccctc cggatacagc agcacatatg ccttctgcac
    11341 ttcctcccac tgcagccgga agccagggcg catgctcggc cggtcggcct gggtcatgac
    11401 tgaactccgt aatgctgtgc catggcgtcg ttcatcgccc acaggatgtc gagcttgaac
    11461 ttcagcacct gcaacgcccg ctgctgttgc tcgcgagtct tgaaacaggc gagcgtcacg
    11521 gccagcccgt gattcacgtc gcgttgggcg agcgaaacgc ggctgcgaaa gtactgcagt
    11581 ccgtcctgct cgatccacgg atagtgctcc ggccacgacg acaaccgttg gcgatgaatg
    11641 gcgggcgcaa acaactccgt cagcgatgag cacaccgctt cctgccacgg cgcctgtcgg
    11701 gcgaaattca cataggcgtc gaccgcgaaa cgcacgccgg gaatcaacca ctgcaattcc
    11761 tccacctcgg cgcgttccaa accgaccgct tcggccaatc gcagccaggc ctcgatgccg
    11821 ccgggatcgt cgccatggcc gtcgtgatcc aggatgcgtt cgacccagcg ccgtcgcacc
    11881 tcccgatccg ggcagttcgc cagaatcgcc gcgtccttgc gcgggatgct gatctgataa
    11941 tagaagcgat tcgccaccca gccctggatc tgttggcggc tcgccttgcc ggtattcagc
    12001 atcacgttga acggatgatg gatgtgatac gcctgcccct gctcccgcaa gtgcagctcg
    12061 aactccgcct cattccaggg aacgtcgccg ctcacagcac gatctccata ccgtcgtacg
    12121 caacctcgat gcggcgttcg ctcaacagcg cgcgctcggg cgagtcctcg accaggatcg
    12181 ggttggtatt gttgatgtga atcagcacgc gccgcgtggt cgccggcagc cggtcgagcc
    12241 aggtgatcat gccgccggtc tgcgatagat gccccatgtc ggccgcgcgc ttgtgagata
    12301 cgccgagccg cacgagctcg tcatcggtcc agaacgtgcc atcgaccagc acgcactgag
    12361 cactgctcat caactcgaac aaccacgaat cgatgttggc gacgccgggc gcgtagcaca
    12421 gccgcgcctc ggttctcaca tcctcgacga tcagtccgat gacatcgccc agcgccgggg
    12481 cacgcgtgga atacggcggc ggccggccgg gcaacgcgat cgcctgccag cgcagatcgt
    12541 cgctgccttc gaccgtgaac cactcgcccg tcacgatgcg ctgccggtcg atgccacagt
    12601 accgctgcag gacctgcaga atggggttcg agatcgtgag atcggcgaag gcattgtccg
    12661 tacaccacag cggccacggc cgcgtcgcct cgcgtagcat caacaggccg gtggtgtgat
    12721 cgatctgcga gtcggtcagg acgatattgc ggataccggt gtcgcgataa gcccggcccg
    12781 gctgcagttg aggattggcc tgcagttgcg ccaggatgtc gggcgacgcg ttgaccagcg
    12841 tccaggcggt ttcatccgcg ccgcggatcg cgatggacga ctgggtgcgc gggcgggcgt
    12901 caagctcctc ccgtcgcacg ccgccgcagt tggggcagtt gcaattccac tgaggaaagc
    12961 caccgccagc ggcagcgcct agaattcgta tgtgcatggg caaggcgagg ctccgggaca
    13021 ctcccggcag ccccgccctc tttcaacgat caacggtgct cggcatacat ggtgatttcc
    13081 atgcccagac gcagatcgat ggccacaggg gtttcccaag tcatggtgga ctccttgtag
    13141 ggaccaaccg cggtcccgac accaccatga cgccatccca ccgccccggc tactcgacaa
    13201 tcatgattcg cgactcatga ttttcatgag cgcggcctgc ctcatacttc gcgccccgcc
    13261 gccggcaagg aaggaccgtt gaaacttcgc acccacgtca acctgatcgt cgccagcctg
    13321 agcgcggcct tcgtgatcct ggcggcgtgg ctgcaattcg acggcacccg gcgtgcagtg
    13381 cgcgaggaga tcgccggggc caacgtcgtg gccacccagc tgctgagccg gattctgatc
    13441 ggttacgacc agcgcgacga tgagcagctg ctgaccttcc tgcagcacct cggccgggtg
    13501 cgcgcccacg agatcacggt gcgcgatgca aaccggcaga tcatctatga atccccgcct
    13561 tcgccctaca aggccggccg cgaagcaccc gcctggtatg catccttcat tctgcccacg
    13621 accccggtgc acatctttcc gctcgcgaac ggctcggagg tgcggatcga agcgaatgcc
    13681 tcgcgcgcca ttctcgatgg ctgggacgat ttcaaacatc tgatgatggt cggtggcatt
    13741 gcgttcgcga tactcaacgc cgcggtgttc tggctggtcg gtcgcgcggt ggcgccctgg
    13801 cccatcatcg tcgaggggct cactcgcatc gagcaaggcg atctgcgcca ccgcctgccg
    13861 aaactgaaag gttacgaagc caacatgatc ggctcgacct tcaaccgcat ggcagtgtcg
    13921 ctcgaagaga aattgctcag cgatcgcaaa gccgtcgaag ccgaacagcg tctgcagcag
    13981 cgccgtgagc tcgaccagct catcgagcag cgactggatg aggaacgacg cgtcatcgcg
    14041 cgcgagctgc acgatgagtt cgcgcaatcg gtgaccgcga ttcgcagctt cgcggtcgtg
    14101 atcgcgaacc aacacccggt cgactcgcag acggccgaag tggctcggct catttcaagc
    14161 gaagcggccc agctttacga cgccatgcac gggttgattc cccgcctcgc gcccctgacg
    14221 ctcgataccc tgggactggc ggaaacactg gagggcttca tcaagcaatg gcaaggccgt
    14281 catcccgcga tccgcttctc gctgcatcac gagttgccca ccgagctcgg gaccagcgcc
    14341 accatcgcgg tgtatcgtgt cgttcaggaa gcggtgatca atgccgtgcg ccatgcgcgt
    14401 cccacgcagg tcgaggtcag tgtcgtgcat tccgactcgc acattcgagt acgcgtcacc
    14461 gacaacggca tcggcctgcc cgaggactgg tcgcggccgg gacatttcgg actgcgcggc
    14521 ttgcaggagc gcatggcgat gttggggggc acacttactt tgaagaaccg cgagccgggc
    14581 ggcgtggcgc tgacggccga gattccgctg ggagagcacg catgatcaga gtgctgctcg
    14641 tcgacgatca cacggtggtg cgcaccggct ttcggctgct gctggaaacc gtgagcgacg
    14701 tgcgcgtaat tgccgaagcc gacagcggtg aaacggcctg cgtgcgtttc gatgaagata
    14761 aacccgacgt ggttgtgctc gatctttcca tgcccggcat gggcggcctg gaaaccctgc
    14821 gccgcctgcg agctcgcgac aaggaggtga aaaccctggc cctgtccgcg cacgacgacg
    14881 ccatccatgc ccggcgtgca ctgaaacaag gcgccttggg cttcctttcc aaacgcaccg
    14941 ccccggaaac attgctcgaa gcggtgcgga tggtcgcggc cggtcaacgt tacatcgatc
    15001 ccaagctcgc ccaggagatc gccctggccg aggtcggcgg cgcgacgctg gtcgatgccc
    15061 tgtctgaacg ggagttcgaa gtgttcctgc gcctggccaa cggcgccgcc gtgccgaaaa
    15121 tcgccgccga gctgaacctg tccacttcca cggtcggcac ccatctctat aacatcaaac
    15181 aaaagctgca cgccggcaat caggccgagc tgaccctgat cgcgctgcgc gccgggctga
    15241 tcgagcgctg aggcccgtca aaagtgtcga ttgcatcggc cccttcgtca tagcagcagg
    15301 gagaccaatg agagagacgg ccgatgcgac aactgcgcga tacgatctcg accgtgctgt
    15361 gcggggccct gctggcggcc accgcccaga ccagcctcgc cgccgacacc atcgatctgg
    15421 cagcggcacc gctgaaccat gccttgatga atttcgccac gatgtgcgga attaccatca
    15481 ccgtcccggc cgatctggct cgcaatcgcc tgtccgaacc tctgaagggc gaacgttgtg
    15541 gcgaagtcgc gctccagcgt ctgctgcaag ggtcgggtct ttcctataag aaggcaccgg
    15601 acggcggcat cgccatcgtc gccatcgcgc cgtccttgcg gaccgccgcc gcagtgacgc
    15661 ccgcaccgcg ccgactcgca gctgccgcag ctcccgcccc ggctccgcag accaaagccg
    15721 acgacgcacc catcctggaa gaggtgaccg tcactgccgg caagcgcggt gaggaacggt
    15781 tgcaggatgt gcccgtcagc atcacggcgc tcactcagga aacgatcgtg caggccggca
    15841 tggacaactt cctcgactac gctcgcagcg tgccgggcgt gggcttcaaa atcacttctc
    15901 ctgccggcgg acgtgacgac ctgcgcggtg gacgtcgcgt gaacattcga ggtatcgaat
    15961 ccggcttcga cagcgtaccg acgacggcct tctatctcga tgaagcgcca gtgcccgtga
    16021 tggatccgaa gctgttcgac gtcgagcgca tcgaagtcct gcgcggcccg cagggcacgt
    16081 tgtatggcgc gaactcgatg ggcggcacgg tgcgcgtggt gctgaacaag ccgcgcctgg
    16141 atgattattt ctacgacgcc gaggtcaccg cctccgccac cgcacacggc gatgaaggct
    16201 atcgcgtcaa ctcgatggtc aatgcgccgc tgatcgaaga caaaggtcgc tcggactcac
    16261 ccgcgcgccg tcggatttcg acgcggacga gctcaccagc tatgaggtcg gctggaaagc
    16321 ggaactggcc gatcgtcgcg tgcgcctcaa cacctcggcg tacttcatcg attggaagga
    16381 cgtgcagaag acggtgcaga tgttcaattg cggcttcagc ttcatcggca acatcggcgc
    16441 ggcggaaagc aaaggcgccg agatcgagct cgccgcgacg ccgatcaacg gcctcgacat
    16501 cggcgcgagc gccggctaca ccgatgcgca atacaccaag agcagcgtcg aagccggcgt
    16561 gatggcgggc gatccctttc ccatcgtgcc gcaatggacg gcatcggcct ccgtgcaata
    16621 ccgcttcccc atcatcgggg ggcgttcggc gcacgtgcgt gccgatgctc agtatgtcga
    16681 caaatccatt tcggatttct tctcgcacga cggcctgccg gtcgtgcagc cttcctacga
    16741 gctggtcaac atgcgcttcg gcatggattt gaccgagcga ctcgcggtga cggtctcggt
    16801 cgacaacgta ttcgacgagc ggcccgtgct cgacaccgtc gattacggcc cgccgtatgg
    16861 attcatcacc tcgacatcgc gcccgcgcac gttcggcctg acgtttcgtt acagcggacg
    16921 ctgatcgggc gcgggaagaa tgcggacctg cgtgaggagg cgctgcgagc cgcccgcgcc
    16981 gcgtactgat cgatccgacg ccgccgcgca tgatgcgcgg aatgaaccgg tcgcttcgtc
    17041 tttgctcgtc gctgctagcg agcttgctgg ctctggtcca gccggcggcc cactctcaac
    17101 aaaccccacc gcagccgacg acgccctccg ccgaagatca agcaaaggcc cagcccttca
    17161 agcctgaaga actggagcag atcgtcgcgc ccatcgcgct ctatccggac gcgctgctgg
    17221 cgcaggtgct catggcatcg acctatccgc tcgagatcgt gctcgcggcg cgctggtcgg
    17281 cggaccatcc cgacgtcaag ggcgacgccg ttgcaaaggc ggtggagaac gagacctggg
    17341 atgcgagcgt caaatccatg gtcgcgtttc cagacgtgct caagatgatg aacgagaagc
    17401 tcgactggac ccagaagctc ggcgacgccg tgctcgcgca acgcaaggac gtgatggacg
    17461 ccgtccagcg attgcgggtc aaggcgaaag acgccggcaa tctgaagagc ggcaaggaac
    17521 aaacggtcaa gaccgaagcc gcgccggcgg gctcgaccgc gcctcaggtc atcatcatcg
    17581 agtcgcccag tcccgaagtc gtctacgttc cgacctacaa cccgaccgtg gtctacgggg
    17641 cctggccgta ccctgcttat ccaccctatt actactaccc gcccggctat gcggccggcg
    17701 cggcgttctt cactttcagc gcgggcgtga tcgtcggcgg cgcgctgtgg ggtggcttca
    17761 attggggcca cagcgacatc gacatcaacg tcaatcgtta caacaatttc aaccgcacca
    17821 acatcaacaa cgtcaaccgc acgaatgtca gcaatcgctg ggagcacaac tcggcgcatc
    17881 gtcagggcgt gggctatcga gactccgcga ctcaacaacg atatggccgt ggcagcagcc
    17941 cgcaagcgct gcaggcccgc gagaactatc gcggccgcga tctcaacaac ggccaactcg
    18001 gcacaggcgg tcaacagaac cgcgatctgg gcgccaatga gtcgcgggat cttggcggtc
    18061 gcacgaacga aaatcgcaac ctcggtggcg gcggtgaaaa ccgcgatctc ggcaatcgcg
    18121 gcaatgaata tcgagacctc gggggtggcg ccgagaaccg ggatctgggc agtgcgtctc
    18181 gcgacttcga tcgcggtggc ggcggatcgt cggacgcgtt tcgcggtgtc gacagtggag
    18241 cgagcacgcg agcccacagc agtcgtggcg cggcgagtcg cggtggcatg tcacgcggtg
    18301 gcggacggcg cagatgaaac agcaaatctc atccaccttg cgaatattca tgctcctgct
    18361 gatgatggca gcggctgcgt gcaatcgcgg cactcagagg gatttcgcat cgatcgatga
    18421 cgccgtgggt gcactggtcg cagcggcccg ctcggacgac acgagggcac tggtgaaagt
    18481 gctcggcgcc gaagccgagc ccgccatctc atccggcgat cccatccaag accgaaatgc
    18541 ccgcgagcga ttcgtacgtg cctacgaaac cgaacataca ttgagtcgtg gcgccgccgg
    18601 tgaagccacg ctgctggtcg gcaccgatca atggccattt ccgtttccgc tggttcaaag
    18661 caatgggcgc tggcacttcg acagcgacgc cggcaccgac gaaatcgtca atcgccgcgt
    18721 cggcgccaac gaactggcca ccatccagtc ctgcctcgcc ttcgtcgatg cccagcgcga
    18781 gtactacatg cgcaacccgc aaggagctgc gctgctgcag ttttcacaga ggctggtgag
    18841 ctcaaaggga cagaaggacg gcctgtattg gccaacgacc ggcaatgagc cgccgagccc
    18901 gctcggcgaa ggcttcgccc gcgcgcaagg cgaaggctat ttccagaatg gtccgtcgaa
    18961 gaatgagccg ctgcgcggtt acatctatcg gctgctgacg gcacaaggcc ccaatgcgcg
    19021 aggcggcgcg tatagctatt tggtcgatgg caagatgatc gggggcttcg cgctgatcac
    19081 cattcccgcc gagtacgggc gcagcggtgt aatgaccttc atcgtgaatc acgacggcgt
    19141 cgtttactca aaggatctcg gtcccgatac gcccaccgcc gcgcgggcca tccagacgtt
    19201 cgatccagat tcgagctggc agcccgaagt cgcaaccgga cagccaatgg ccgcgcagat
    19261 cgcccccgcc gtggttcagt ttctcggtga agccggcttc gaccacgaac gagacatcct
    19321 gatgggaatc ctgcgctgac gccggtcgag tgatacgcca gtcacatccc ctgcgccggc
    19381 gctgacgagc cgagtcggtg ccagcagtca gccctgctcc ggcgccgtta cagagcggtt
    19441 atatcgttgc ccgttatggc gacattcgga ttcattcctt ctgcgtcggc tgggcatacc
    19501 ctacgctgtt cctcactgtg aacggcaacg actccatcat gtccaccgaa cggcccaaca
    19561 acgtgatcgc tctggcgccc tatcgtttcg cgcaccaggc cagccagcgc cgctcgcgtc
    19621 cctacgtgac gtggtatccc aacgtgggct tcgtcgcccc gacgccgaac acactcgcgc
    19681 cgatccgtca gctgcgcacc gctcgcggtc cggagtcgat gtgatttgtg gtcgactcca
    19741 gcgcgccgcc tccgctcctg gatagcggac gaacggccgt gcggacggcc gtccgggccg
    19801 gaagagcgct cagccgccct tcagtttctg cacgatttcc agcgacttgt tgacgttctc
    19861 caccgggttg aggccgccga ccgtggccgc gaccttgccg tccggggtca cgatgaacgt
    19921 ggtgcgctcg gcgaagccat ggtcgatatc ctggccccgc gtgtccttct tgccggtgcc
    19981 agcttcacgc acctgcagtt cataggactt cgcaatcttc ccgtccacgt ccgaggccgt
    20041 cgggaacttg cccgcgcaat attcggggtc cttggagaag tcgttgagcc gctcgatgct
    20101 gtcgagcgaa acgccgatga tgctggcgcc ggcggcggcg aacttatcct tgttgacggc
    20161 gaacgtacga gcttgcacgt tgcagccgcc ggtgtacgcg gacggataga aatagaccac
    20221 gaccgggccc ttcttcagcg catccttgag cgaatatgta aacggtttgc ctgccagcga
    20281 cgcctgcgcc gtgaactcgg gcgccggcgc cccctcctgt aacgcggcca gtgccggcag
    20341 cgcggtcaat cccaacagac cggtcaagag caaaccctgc gttttcatga ggactccagc
    20401 agcagtggac ggaacgcatg catcgtagcc ctccggcggc cgggcgtcat ccgacacggt
    20461 gcgggccggt cgatatcttc caaaaacccg cccggccgcg catgactgca gttcagtcct
    20521 ggttcacagc gttgcgccag tctttcaaaa agcgcaggcg tttgatttga tcgagattgg
    20581 ccagcagttc cggcccgacc cggatcgcgc gcatgttggg cgcgtcgatg tgagttccgg
    20641 gcggcgcgtc gacatcgctg cgcaccggcg tcatgtgctt ttgagcgagg aacgcctggc
    20701 cgcgcctgga caggagataa tccagaaaca gcttggccgc gtccggatga cgcgcatcgg
    20761 cgggaatcaa ggcgatgcgg gacgccacca acgtgtagtc gctcggcagg atgaccccga
    20821 tggcaggatc gcgcgccgca cgctccagcg catacggtcc gatggtgttg taggcgagca
    20881 gatgttcgcc cgacgccacg cgctcgagca tcgcgcccgt cgacgaatag aattgcacct
    20941 tggctcgccc catggcatgc accagacgcc agttgtcgcg agtgacgcga agatcctgcg
    21001 tcatatagag gaacccggcg ccggagcgct cgggatccat catcgcaacc ttgccgacgt
    21061 agctgggatt gtcggtcagc aagcgctcca ggtcggcgcg ggtgtgcgga acctcggccg
    21121 ccggcaccag ccgtttgtta taaaccagca ccaccggctc ggccgtggtg ccgtacgcct
    21181 cgttcttcca gatcgcccag gcgggcagat tcggcttttc cggcgacgcg tacgcttgcg
    21241 catacccgtc gttcaccagt ttgatctgca gatccatcgc cgagctccac agcagatccg
    21301 cgctcgcttc cttggccgcg acctcggcga tgaaacggtt gtacagctcg gtcgaattga
    21361 tatcgaagta ctcgacgcgg atccgcggat agagcgaacg aaagtcctgc agcagttggg
    21421 cgacttcgcg cgcgtcggtg gtcgaataga tgctgagcct gccatcctcg ttcgcatccg
    21481 cgattcgatt cgcgtacgaa cgcggatagc tcggcggcac ggcggcgatc gccgacagcg
    21541 ccgtggcaag caagagcacc gcggcggcca ctgttttcgc cagacgcatc atcgcttcgg
    21601 tcgctgtaaa tgctgtgggc aatagcatgc agcctatccc ccttggctcg ctacgttagg
    21661 cattgatact gtcgccaacc tgtcatgcaa ttcgaggcgt tcgcttggcc cgcatcctgc
    21721 tcgtcgagga cgatcctgcg ctacgccgtg gcctcgtggc aacgctgcgt gccgccggct
    21781 atgccgtgga caccgcgggc gatggcactt ccggcctcga gatcgcccgc aaggagccgt
    21841 acgcgctcat cattctggat gtcggcctgc ccggcatttc cggtttcgag gtgctcagac
    21901 ggctgcgcaa agggggcacg aaaacgccca ttctgatcct caccgcacgc gatacggtgc
    21961 aggaccgggt caccggactg gacctgggcg cggacgacta tctgctcaag ccgttcgagc
    22021 cgaacgagct ggaagcgcgc attcgcgccc tgctccgccg ctcgcaaggc gatccctcgc
    22081 cggtcgtgac catcg
//
