LOCUS       NZ_CP035501            20894 bp    DNA     circular CON 23-AUG-2024
DEFINITION  Sphingosinicella sp. BN140058 chromosome, complete genome.
ACCESSION   NZ_CP035501
VERSION     NZ_CP035501.1
KEYWORDS    RefSeq.
SOURCE      Sphingosinicella sp. BN140058
  ORGANISM  Sphingosinicella sp. BN140058
            Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
            Sphingosinicellaceae; Sphingosinicella.
REFERENCE   1  (bases 1 to 5729595)
  AUTHORS   Jin,C.
  TITLE     Sphingosinicella pituitosa sp. nov., polysaccharide producing
            bacteria, isolated from soil
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5729595)
  AUTHORS   Jin,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2019) Industrial Bio-Material Research Center,
            Korea Research Institute of Biotechnology Bioscience, Gwahak-Ro,
            Daejeon 305-806, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 204.0x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004135585.1-RS_2024_08_23
            Annotation Date                   :: 08/23/2024 20:22:59
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,668
            CDSs (total)                      :: 5,600
            Genes (coding)                    :: 5,564
            CDSs (with protein)               :: 5,564
            Genes (RNA)                       :: 68
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 36
            CDSs (without protein)            :: 36
            Pseudo Genes (ambiguous residues) :: 0 of 36
            Pseudo Genes (frameshifted)       :: 7 of 36
            Pseudo Genes (incomplete)         :: 29 of 36
            Pseudo Genes (internal stop)      :: 6 of 36
            Pseudo Genes (multiple problems)  :: 6 of 36
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:34:38
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1054991
            Orig. end                         :: 1075885
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP035501.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20894
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="2"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20894
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20894
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10894](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10894)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(1528..2994)
                     /locus_tag="ETR14_RS04735"
                     /old_locus_tag="ETR14_04735"
     CDS             complement(1528..2994)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014893.5"
                     /locus_tag="ETR14_RS04735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETR14_04735"
                     /product="Gfo/Idh/MocA family protein"
                     /protein_id="WP_129383598.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 2.4e-19, bitscore:
                     68.5, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 1.3e-14,
                     bitscore: 52.5, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEEADDLGLGRREVMAGMAGGAAIASIPSAPARAATGGRRFVQV
                     GCGSRARMFQEAIWGPHKTTSSLVAICDTNPGRLAYAARRAAAAGAPAPQTYLAADFTR
                     MLKEHRPDAVIVTVPDAYHVDYIVGALDAGIDVITEKPMTTDAAKAQAILDAVKRSGRH
                     VRVTFNYRYAPFRTQVKELLMAGEIGDVLSVDFTWLLNTVHGADYFRRWHSNKAISGGL
                     MVHKATHHFDLVNWWLSDVPATVNATGKRQFYTPEMARRMGLDGPHQRCRTCPEKAECN
                     FYLDIAADPGLKALYVDNERYDGYFRDQCVWRPEISIEDTMNVIVGYEGGATLSYSLNA
                     FNAWEGYHVAFNGTKGRLEHNVVEKAYVAGATMTQGESDEDAVTTRIVPLRGAPRTIKP
                     RTGEGGHGGGDAVMLTDLFDPAAPADPLLRAADERGGACSILIGIAANQCFKTGKEVKI
                     AELVSGLRRPDLPAMPSHGQPVPMPPRVVR"
     gene            3179..5845
                     /locus_tag="ETR14_RS04740"
                     /old_locus_tag="ETR14_04740"
     CDS             3179..5845
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010163440.1"
                     /locus_tag="ETR14_RS04740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETR14_04740"
                     /product="glycoside hydrolase family 3 protein"
                     /protein_id="WP_243455766.1"
                     /transl_table=11
                     /translation="MSRKLLIAIALLATAARPAAAIAQSTAAPAAAPANLPFRNPALRV
                     EQRAADIVSRMTLEEKARQLGHTAPAIPRLGVPEYNWWNEGLHGVARAGVATVFPQAIG
                     MAASWDAPLMQSVGDVISTEFRAKYAERVHPDGGTDWYRGLTVWSPNINIFRDPRWGRG
                     QETYGEDPYLTSRIGIAFIRGLQGDDPNLFKTIATSKHFAVHSGPESNRHREDVHPSPH
                     DLEDTYLPAFRATVTEGQVYSVMCAYNAVGGVPACASQDLLDTRLRRDWGFKGFVVSDC
                     GAAANIFREDSLRYTKTPEEGVAAGFKAGMDLICGDYRNNMSTEPEHIVAAVRSGQLPE
                     AVVDQALRRLFEARIRLGLFDPPASRPFANIGPEQNDTPEHRAMALKMAQASMVLLKND
                     GLLPLKQAPKRIAVIGPNADNVDALVGNYNGTPSAPVTVLAGLRARFPDARIDFVEGTG
                     LVGPASPPVPDAIFCTDAGCGTRGLKAEVFRGVNLEGAPTETRTDPNAVFEWRGDRESS
                     IRWTGTITPTESGEHRFRVASDNGYRVFIGDTAVVDEWGVGDAPSIADGTIRLEAGKSY
                     PIRVEAFQRGVRGRQRLLWSPPSENGDKAIAAARNADLVVFAGGLTARVEGEEMKIAAA
                     GFAGGDRTSIDLPAPQQKLLERVQAVGKPVVLVLMNGSALGVNWADKNVPAIVEAWYPG
                     GEGGHAVAGLLAGDFSPAGRLPVTFYRSVDQLPAFADYRMAGRTYRYFAGEPLYPFGHG
                     LSYTRFRYANLRTSAASVAAGTPLTVTADVTNDGAVDGDEVVQLYVSRAGQAGTPIRAL
                     QGFQRVPIKRGETRTISFTLDDRALSVVDDKGVRKVTPGDVELWVGGGQPVSRPGLPAV
                     AGTKARVRVTGTRTLPR"
     gene            5891..6703
                     /locus_tag="ETR14_RS04745"
                     /old_locus_tag="ETR14_04745"
     CDS             5891..6703
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010127030.1"
                     /locus_tag="ETR14_RS04745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETR14_04745"
                     /product="SirB1 family protein"
                     /protein_id="WP_129383600.1"
                     /transl_table=11
                     /translation="MNFEIAHLGLVDEELIAPEIAALELAALDHPGVELDPYFDILSEI
                     AEELADVGAGAASAPEQALALAEVIGASYEFDGDREKYDDRQNVDMIRVIDRRRGMPIS
                     LSILYVGLARRIGWPADALNTPGHVLVRIGPDTAPLLIDPFNGGTIVNADRLTTLLSHV
                     LGADVSPSAEHLAPMSNRSMLVRLLMNEATRAEAAGDPERALVLFERMTVVAPANSHAW
                     WEKARLELVGNDASAARGSLSALLEMTRDPNMRGHISAMLDSLARPST"
     gene            complement(6720..6962)
                     /locus_tag="ETR14_RS04750"
                     /old_locus_tag="ETR14_04750"
     CDS             complement(6720..6962)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008994732.1"
                     /locus_tag="ETR14_RS04750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETR14_04750"
                     /product="DUF6582 domain-containing protein"
                     /protein_id="WP_129383601.1"
                     /transl_table=11
                     /translation="MSKLSADERDHLGKGAFAFPETRKEPLENASHVRNAIARFNQVKG
                     VSDADRDAAWKRIRTAAAKFGVEVSETDWREIGRK"
     misc_feature    complement(6986..7000)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 20.56"
                     /tool="antismash"
     gene            complement(6998..7546)
                     /locus_tag="ETR14_RS04755"
                     /old_locus_tag="ETR14_04755"
                     /pseudo=""
     CDS             complement(6998..7546)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017181474.1"
                     /locus_tag="ETR14_RS04755"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="ETR14_04755"
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MPDISDARILIIATNGFEDSELMDPLNTLKQKGAAVTLASLSRDE
                     IEGDKGARIAPDVEIGDVDGGAFDALLLPGGTKNPDKLRTEQAVISMVRQFVEAGKPVA
                     AICHGP"
     gene            complement(7628..8653)
                     /gene="queA"
                     /locus_tag="ETR14_RS04760"
                     /old_locus_tag="ETR14_04760"
     CDS             complement(7628..8653)
                     /EC_number="2.4.99.17"
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="queA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007710028.1"
                     /locus_tag="ETR14_RS04760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETR14_04760"
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="WP_129383602.1"
                     /transl_table=11
                     /translation="MRVDLFDFELPPERIALRPAEPRDSARLLLVRPDGLADHSVADLP
                     QLLRPGDVLVFNDTRVIPAQLEGRRGDARIGATLHKREGLRDWRAFVRNAKRVRDGDRI
                     DFGAGVTALAGEKAEDGSILLSFDGEEPVELLLERAGRMPLPPYIAARREADARDVEDY
                     QTMFAREKGAVAAPTAALHFTPALIDALGRRGIAHETLTLHVGAGTFLPVKADDTDDHR
                     MHSEWGRIDAAAAERLNAARAEGGRIIAVGTTSLRLLESATGEDGIVRPFEGDTAIFIT
                     PGYRFRAIGGLLTNFHLPRSTLFMLVSALMGRETMQAAYAHAIKGGYRFYSYGDASLLL
                     P"
     misc_feature    8649..8665
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 22.03"
                     /tool="antismash"
     gene            complement(8655..9386)
                     /locus_tag="ETR14_RS04765"
                     /old_locus_tag="ETR14_04765"
     CDS             complement(8655..9386)
                     /EC_number="5.2.1.8"
                     /GO_function="GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /GO_process="GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017979932.1"
                     /locus_tag="ETR14_RS04765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETR14_04765"
                     /product="peptidylprolyl isomerase"
                     /protein_id="WP_129383603.1"
                     /transl_table=11
                     /translation="MRIKALIALLMGFFFASALAAQQPAATPFVPPPLDPENTLVLDLS
                     TGGRVTIQLRPDVAPGHVERYKTLVRRGFYNGLAFHRVIDGFMAQGGDPKGDGSGGSDL
                     PDLKAEFNALPHVRGAVSAARTDAPDTANSQFFIMFAPRFSLDNKYTVFGRVVSGMNYV
                     DAIERGEPPMNPSRIIKASIGADNVAPPTPAEVAAVMAAHQPAAPAGPTLLPIQGGAAA
                     PAPAPATEAQPAPAQGTPKQQ"
     misc_feature    complement(9376..9389)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.57"
                     /tool="antismash"
     misc_feature    9384..9399
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.76"
                     /tool="antismash"
     misc_feature    9386..9400
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 23.68"
                     /tool="antismash"
     gene            complement(9439..9939)
                     /gene="coaD"
                     /locus_tag="ETR14_RS04770"
                     /old_locus_tag="ETR14_04770"
     CDS             complement(9439..9939)
                     /EC_number="2.7.7.3"
                     /GO_function="GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="coaD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011950876.1"
                     /locus_tag="ETR14_RS04770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETR14_04770"
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="WP_129383604.1"
                     /sec_met_domain="CTP_transf_like (E-value: 3.3e-20,
                     bitscore: 71.0, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIGVYPGTFDPITLGHIDIIRRGAKLVDRLVIGVTTNPSKSPMF
                     TVEERIAMVRRELADMDGAISVVSFDSLLMDFAERQGASMIVRGLRAVADFEYEYQMAG
                     MNQQLNADIETVFLMADVSLQPIASRLVKEIALYGGDIGKFVTACVAVDVAARVEKLGR
                     KGS"
     gene            complement(10001..10894)
                     /locus_tag="ETR14_RS04775"
                     /old_locus_tag="ETR14_04775"
     CDS             complement(10001..10894)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013833550.1"
                     /locus_tag="ETR14_RS04775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETR14_04775"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_129383605.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 5e-53, bitscore:
                     178.3, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADSLLAPAFDRIRSEIDTLFDALLAVPPDPRARLFEAMRYAAMG
                     AGKRLRPLLVTASAGLFHVDRQRALRVGAAVEAIHVYSLIHDDLPCMDDDDIRRGKPTL
                     HKAYDEATAVLAGDSLHALAFEILGDEATHEDPFVRSELIGELARAAGPSGMAGGQMMD
                     MVAAESALDLSAVTRLQQLKTGALIGFCLEAGAIMGRVPPEGRTKLRGYARDVGLAFQI
                     ADDLLDEEGEEEKIGKKVGKDRDQGKETFVTLLGRDRARQQAKLLVSQGIEYLASYGAE
                     ADLLRAIARFAVERDH"
     misc_feature    10863..10878
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.44"
                     /tool="antismash"
     misc_feature    10879..10893
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.35"
                     /tool="antismash"
     gene            complement(10905..11153)
                     /locus_tag="ETR14_RS04780"
                     /old_locus_tag="ETR14_04780"
     CDS             complement(10905..11153)
                     /EC_number="3.1.11.6"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008066003.1"
                     /locus_tag="ETR14_RS04780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETR14_04780"
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_206185968.1"
                     /transl_table=11
                     /translation="MSDQNDAISELSFEAALKRLEEIVRRLESGDASLDESIQLYGEGD
                     RLRQQCEARLQAAQARIEKIQIGRDGQPAGTAPFDPA"
     gene            11271..11681
                     /locus_tag="ETR14_RS04785"
                     /old_locus_tag="ETR14_04785"
     CDS             11271..11681
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ETR14_RS04785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ETR14_04785"
                     /product="hypothetical protein"
                     /protein_id="WP_129383606.1"
                     /transl_table=11
                     /translation="MAHDPDPAMMAAPEALARFLETRNEAMLWSVFSDSDDVTILENFP
                     PHLFRGRAGVSRWRELMAEHVGKLEQLRHAFGPAQDYGETEDQAFFTLPTAWTGLRDGM
                     PFTEHGGWSFLMAREEQGWRIRAYAWAVTSFT"
     gene            complement(11706..14747)
                     /locus_tag="ETR14_RS04790"
                     /old_locus_tag="ETR14_04790"
     CDS             complement(11706..14747)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019830897.1"
                     /locus_tag="ETR14_RS04790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETR14_04790"
                     /product="glycosyl hydrolase family 28-related protein"
                     /protein_id="WP_243455767.1"
                     /transl_table=11
                     /translation="MTPRLIAALLLAGAALPALAAPPSSFTAIPADPRAVTVNAVGDGK
                     ADDGAAIQAAINAAEAKGGGGIVFLPSGRYRIGRTIFVWPGVRVFGTGKTRPTILLGAA
                     TPGFQQGVGSMLFFTGNRPGGAAPGPGGVVAPARVPVPPPTSVPFNPEIADANSGTFYS
                     ALSNVDFEIGEGNPAATAVRFHTAQHAFLSHIDFRLGSALAGIYQAGNVGQDLRFFGGR
                     YGILTEKPSAAWQYTLLDSEFDGQRDAAIREHEAGLTLVNTRFRNVPVGIEIDEGYGDW
                     LWGKDVRFENVARAGVIISNEGNAYTQVGFDNAVASGTPVFARFRDSGRTVAGPAARYR
                     VKEFTYGLTVPAIGQTGRFETRMDAAPLRALPARRAPAIRALPGTASWANVRDLGIKGD
                     GSSDDTAALQRAIDTHRVLYFPAGFYRVSDRLTLRPDSVLIGLHPSLTRITLADDSPAY
                     RGIGSPRALLESAKGGTAIVSGLGLDTGGINPRATALLWRAGETSLVDDVRFLGGHGTN
                     AADGSRIDPYNANHTADPDPRKRWDGQYSSLWVTDGGGGTFNNLWTPNTFAQSGMFVSN
                     TSTPGFVYEMSAEHHARAEIVLDGVRNWEFLAPQTEEEAGESRNAVSLEVRNSRDILFA
                     NYHGYRVTRSLQPAPAAVRLYNSTDIRFRNVHVNAESGFATCDANGCGTYLRASKYPYE
                     NAIQDMTSGLEVREREFARLDVAAAPPPPATPSLVPVRKLGGGFASLGGGAVDGAGKLY
                     FIDRPFQRIHGWSEDQGLSIVADAPLDPVNLAVDRSGDLLVLSSDGPEASVYSIDPDRP
                     DKVTVIAPTPVSPKAERQIALPASFWNNGEFRDQYDPARDRFTTLAEMFARDAATPKPR
                     EYVSPDGSVALPAFRVWQQGPSNFLGWRFSDTLDTYGFVGGKVGDRVFVSNSSEDRTYS
                     ALLGAGGALTDLKPFASRGGESVATGANGRVYVANGQIFVFTADGREAGRIDVPERPLQ
                     LLFGGAGGRTLFILTHHGLYAAEP"
     misc_feature    14743..14758
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 18.42"
                     /tool="antismash"
     gene            14923..15450
                     /locus_tag="ETR14_RS04795"
                     /old_locus_tag="ETR14_04795"
     CDS             14923..15450
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0046316 - gluconokinase activity [Evidence
                     IEA]"
                     /GO_process="GO:0046177 - D-gluconate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010216114.1"
                     /locus_tag="ETR14_RS04795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETR14_04795"
                     /product="gluconokinase"
                     /protein_id="WP_371416746.1"
                     /transl_table=11
                     /translation="MPPLAIVVMGVSGCGKSTLGARLAAEFDCPFLEGDSYHLPESVAK
                     MRAGQPLGDDDRWPWLDRLGAAAGDALRADGMSVVACSALKRVYRERLACAARAPMRFV
                     LLEAEPAELIRRLGQRPEHYMPASLLDSQFAILERPGADEAALTLDAALPPERLAERVT
                     AWARTEIAAHSL"
     gene            complement(15447..16124)
                     /locus_tag="ETR14_RS04800"
                     /old_locus_tag="ETR14_04800"
     CDS             complement(15447..16124)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004211036.1"
                     /locus_tag="ETR14_RS04800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETR14_04800"
                     /product="FadR/GntR family transcriptional regulator"
                     /protein_id="WP_129391346.1"
                     /transl_table=11
                     /translation="MNEGRLADRAYTGIVQIINDDNLAAGDRLPSESRLAEMFGMSRTI
                     VREALVRLASDGITEARRGAGSYVKRRPSERLGAHMPMAELAATLGTYEVRFVLEAEAA
                     RLAAQRRSSEQLACIEGHLADLRAALLSSAPAHEEDWLLHRAIAEATANTAFVSIFDHL
                     HDEVEKILKAGVDISRARPPEVIAAMMGEHDAIVDAIRAQDGDGAALAMRWHLSQGRKR
                     LMP"
     gene            complement(16165..17508)
                     /locus_tag="ETR14_RS04805"
                     /old_locus_tag="ETR14_04805"
     CDS             complement(16165..17508)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015128 - gluconate transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0035429 - gluconate transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010402331.1"
                     /locus_tag="ETR14_RS04805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETR14_04805"
                     /product="gluconate:H+ symporter"
                     /protein_id="WP_129383607.1"
                     /transl_table=11
                     /translation="MSADDFRLVGAALCGIFLAVLLIVRGRLHPFVGLLCGAFTVGLVA
                     GVPMADTAKAVQKGVGDILGGTGLVVALGLSLGAMLQLSGAAAALATTGLRLTGPRAAP
                     WASLGIAIVIGLPLFFETGLVLLLPIVAAAAAALPDGEGKDRARLGLMLPALAGLSVVH
                     ALVPPHPGPLLAVEAIGADLGMTMLYGILIAIPTAAIAGPALALVTARGVRLTPPAIEG
                     PAMVGTPPRRDLALLIVLLPVVLIAAGALGPLVPALAGSAWLAAASNPVMALLITNLVA
                     LPILFGRRLRDATIQDAIWSETMAAAGTTLLAIGAGGALKQVLVTAGLSDLLARLASLQ
                     AISPLLLGWLVAVGIRLATGSATVATITAVGVMPGVVAASGASPELVVLAIGAGSVFFS
                     HVNDPGFWLVKGYLGTSTPDTFRTWSMLETAISVVGLAMVMAASYFVG"
     gene            17768..18016
                     /locus_tag="ETR14_RS04810"
                     /old_locus_tag="ETR14_04810"
     CDS             17768..18016
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010544516.1"
                     /locus_tag="ETR14_RS04810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETR14_04810"
                     /product="response regulator transcription factor"
                     /protein_id="WP_129383608.1"
                     /transl_table=11
                     /translation="MQGFSESGPAPQGNVAAIATLTPTQLKVLHGVHSGLLNKQIAYDL
                     GIAEATVKAHMTALMRKLNVRNRTQVALAAHALTASN"
ORIGIN
        1 cagctggacg cgaccgccgt ccagtgcctc tgccccgatc gcaagtgaga cctggccccg
       61 gctggtgaac ttgacagcat tgccgagcag attgatcagc acctggcgaa ggcgcttctg
      121 gtccccggtc acgatgtgag gcaccccgtc gtcgatcgcg cagacgaagc ccaatccttt
      181 ctcttcggcg cggatccgca tcatgttggc gatgccggcg agacaggcgt ggagatcgaa
      241 gcgtcccggc accagttcga gcctgcccgc ttcgatcttg gacagatcga ggatgtcgtt
      301 gatcagggtg agcagatggg ttccgctctg gtgaatggtc tgggccgcga cagtctgccg
      361 cgcgtccagc gtctcgcgct cgagcaattg ggcgtagccg aggatggcgt tgagcggcgt
      421 gcgcagctcg tggctcatgt tggcgagaaa ggcggatttg gcggcgctgg cgctttccgc
      481 catcgccttg gctgccgcaa gctcgcggct ctcctgaacc tggcgctggt gtcgggtctc
      541 gaaaccccgc cgcacctgga agaagcgatg gatcaggaac gcgccgatca gcaggatcca
      601 caggccgagc agcaccagat aatattgcgc ctgcgaaatc tgccggccct ggagcttgat
      661 gctctcgacc tcgaattcat ggtggccgac cctagcatcc gatccgggct gaacttcgat
      721 cgcagtgacg ttgtcgatct tcggttcggc caattccttg gacagcttgt ttgccgccgc
      781 ccaccattcg gcgacgaaga tctcgccgag atcgagcgtc accgtctgct gtccctggcg
      841 gactgcgaac tccatctggt tcggcttgct cccggcactg ctatgccgcg gatcggaatt
      901 gatgaaggcg atccgcatct tggctgccgg gccggaatag cggaagctga gcgagatctt
      961 ctgatatctc gagaagtcga gcccttcgcc gcgccccgtc ttgtcgaaca gcagaccgta
     1021 gccgcaaaat ggatattggt agccggaccg gagctcgcac gaccagcgca tggccctggt
     1081 cttgtccaac gtgatcgtcg atgtgccctg gcttggcgca tcggtgtagg aataagccgc
     1141 ataggccgcg ggattgtccg gcgtgtacga caggtgcttc gcggtgaaga gttcctggaa
     1201 ctggatggcc gcgaacgtga tcagcatcag tgcgagcacc gcggcttcga gcttgagcct
     1261 ggagatcaga cgcaccgggt cctcggccga cgcaggcgca ctgccgccgc gtccgtcatg
     1321 gaacgaaggt acatccgcat cccgtgcggc aaccgtcgcc ggcagctctg aatcccgctt
     1381 cgtcatccca cccctaccca acaaaaagac ggtagggatc aggccttaag tcccgctcta
     1441 tgccggacta gggaaattgc cttagggccg cgccggaagc tgttaacctt ctctaccgat
     1501 gttccatggg cgtctccgcg cttggtctca gcggaccacc cgcggcggca tcggcaccgg
     1561 ctgaccgtgg ctcggcatcg ccggcagatc gggccggcga aggccgctca ccagctcggc
     1621 gatcttcacc tccttgccgg tcttgaaaca ttggttggcg gcgattccga tcaggatcga
     1681 gcaggcgccg ccgcgctcgt cggcggcgcg cagcaagggg tcggcgggcg ccgcaggatc
     1741 aaacaggtcg gtaagcatca ccgcgtcgcc gccgccatgg ccgccttcgc cggtgcgcgg
     1801 cttgatcgtg cgcggcgcgc cgcgaagcgg cacgatccgg gtggtgaccg catcctcgtc
     1861 gctctcgccc tgagtcatcg tcgcgccggc gacataggcc ttctcgacga cattgtgctc
     1921 gagccgcccc ttggtgccgt tgaaggcgac atgatagccc tcccaggcgt tgaaggcgtt
     1981 gaggctgtag gacaaggtcg cgccgccttc gtagccgacg atcacgttca tcgtgtcctc
     2041 gatactgatc tcgggccgcc agacgcactg atcccggaag tagccgtcat agcgctcgtt
     2101 atcgacatag agcgccttca gcccgggatc cgcggcgata tcgaggtaga agttgcattc
     2161 ggccttttcc gggcaggtgc gacagcgctg atgcggcccg tcgaggccca tccgccgcgc
     2221 catctcgggc gtgtagaatt gccttttgcc ggtcgcgttc accgtcgccg gaacgtcgga
     2281 cagccaccaa ttgacgagat caaaatggtg ggtcgccttg tgcaccatca ggccgcccga
     2341 aatcgccttg ttgctgtgcc agcggcgaaa ataatcggcg ccatggacgg tgttgagcag
     2401 ccaggtgaaa tcgacagaca gcacgtcgcc gatctcgccc gccatcagca attccttcac
     2461 ctgcgtgcgg aacggcgcat agcggtaatt gaacgttacc cgcacatggc ggccgctccg
     2521 cttcaccgcg tccaagattg cctgcgcttt ggcggcgtcc gtggtcatcg gcttttcggt
     2581 gatcacgtcg atgccggcgt cgagcgcgcc gacgatataa tcgacgtgat aggcgtccgg
     2641 cacggtgacg atcaccgcgt ccgggcggtg ctccttgagc atcctggtga aatcggcggc
     2701 cagataggtt tgcggcgccg gcgctccggc ggcggcggcg cggcgggcgg cataagcgag
     2761 tcggcccgga ttggtgtcgc agattgcgac caggctgctg gtcgtcttgt gcggtcccca
     2821 gatcgcctcc tggaacatgc gggcgcggct gccgcagccg acctgcacga agcgccggcc
     2881 gcctgtcgcc gcccgtgccg gcgcagacgg gatcgaggcg atcgccgccc cgccggccat
     2941 gccggccatc acctcacgcc ggccgaggcc gagatcgtct gcttcctcag tcatgtcgca
     3001 tccctctccg aggccggtca ttcacgcaac cgccattcca tttcacaaag tgaccgacaa
     3061 tcccaccatg tgcaacatgg catgacgcat gaacgcgcaa tgtgcagccc tccgcggatc
     3121 tggtaacgct aacatttctg acttatgctc ctcaaaaata gacagaggga ggatgtccgt
     3181 gagtcgcaag cttctgatcg caattgccct gctcgccacc gcagcccggc cggcggcggc
     3241 gattgcgcaa tccaccgccg ccccagccgc cgcgccggcg aacctgccct tccgcaaccc
     3301 tgcgctccgc gtggagcaac gtgcggccga catcgtctcg cgcatgacgc tggaggagaa
     3361 agcacgccag ctcggtcata ccgcccctgc catcccgagg ctcggcgtac cggaatataa
     3421 ttggtggaac gaggggttgc acggcgtcgc ccgtgccggc gtcgccaccg tattcccgca
     3481 ggcgatcggt atggcggcct cctgggatgc gccgctgatg caatcggtcg gcgacgtgat
     3541 cagcaccgaa tttcgtgcca aatatgcgga acgcgttcat cccgacggcg gcaccgactg
     3601 gtatcgcggc ctcaccgtct ggtctccgaa catcaacatc ttccgcgatc cgcgctgggg
     3661 gcgcggtcag gaaacctatg gcgaggatcc gtacctgacc tcgcgcatcg gcatcgcctt
     3721 catccggggt ctccagggcg acgatcccaa tctcttcaag acgatcgcca cctccaaaca
     3781 ctttgcagtg cacagcggcc ccgaatcgaa ccgtcaccgc gaggatgtcc acccctcccc
     3841 gcacgatctt gaggacacct atctgcccgc tttccgcgcg accgtcaccg aagggcaggt
     3901 ctattcggtg atgtgcgcct acaatgccgt cggcggtgtt ccggcctgcg ccagccagga
     3961 tctgctcgac accaggttgc gaagggactg gggcttcaag ggcttcgtcg tttccgattg
     4021 cggagccgcc gccaacatct tccgcgaaga cagccttcgt tacacaaaaa cgcccgagga
     4081 aggcgtcgcg gccggcttca aggcgggcat ggaccttatc tgcggcgact atcgcaacaa
     4141 catgagcacc gagcccgagc atatcgtcgc cgccgtccgc tccggccagt tgcccgaagc
     4201 ggtggtcgat caggcgctgc ggcgactgtt cgaagcgcgg atccggcttg gcctcttcga
     4261 cccgccggca tcccgcccgt tcgcgaacat cggtcccgag cagaacgaca cgcccgagca
     4321 tcgcgcgatg gcgctgaaga tggcgcaagc ctcgatggtg ctgctcaaga atgacggcct
     4381 gctgccgttg aagcaggcgc ccaagcggat cgccgtgatc ggacccaatg ccgacaatgt
     4441 cgacgcattg gtcggcaatt acaacggcac cccttcggcc cccgtcacgg tgctggccgg
     4501 cctccgcgcc cgcttcccgg acgcgcggat cgacttcgtc gagggcacgg gcctcgtcgg
     4561 cccggcctca ccgccggttc ccgacgccat cttctgcacc gatgcaggct gcggcacccg
     4621 cggcttgaag gccgaggtct tccgcggcgt caatctggag ggcgcgccga ccgagacccg
     4681 caccgatccc aatgccgtgt tcgaatggcg cggcgatcgc gaaagctcga tccgctggac
     4741 cggaaccatc acgccgaccg agagcggcga gcatcgcttc cgcgtcgcca gcgacaatgg
     4801 ctatcgggtg ttcatcgggg ataccgccgt ggtcgacgag tggggggtcg gcgacgcgcc
     4861 ttcgatcgcc gatggcacca tccgtctcga ggccggcaag agctatccga tacgggtcga
     4921 ggctttccag cgcggcgtgc gcggccgcca gagattgctg tggagcccgc cgagcgagaa
     4981 tggcgacaag gctatagccg cggcgcgcaa tgccgatctc gtcgtattcg ccggcggtct
     5041 aaccgcgcgg gtggaaggcg aggagatgaa gatcgccgca gcgggtttcg ccggtggcga
     5101 ccggaccagc atcgatctcc ccgcacctca gcagaaattg cttgagcggg ttcaggcggt
     5161 tggcaaaccg gtcgtattgg tgctgatgaa cggcagcgcg ctcggcgtga actgggccga
     5221 caagaatgtg cccgccatcg tcgaggcctg gtatccgggc ggcgaaggtg gccatgccgt
     5281 cgccggattg ctcgccggcg atttcagccc cgccggccgc ctgccggtga ccttctacag
     5341 atcggtcgac cagcttccgg ccttcgccga ctatcgcatg gcgggacgga cctatcgcta
     5401 tttcgccggc gagccgcttt acccgttcgg ccacgggctc agctacacgc gctttcgtta
     5461 cgccaatctc aggaccagcg ccgcgtccgt cgctgcgggc acgccgttga cggtgaccgc
     5521 ggacgtcacc aatgacggcg cggtcgatgg cgacgaggtc gttcagctct acgtctcgcg
     5581 ggcgggtcag gccgggacgc cgatccgcgc ccttcagggc tttcagcgcg tgccgatcaa
     5641 gcgaggcgag acccgcacga taagcttcac cctcgacgat cgggcgctca gcgtcgtcga
     5701 cgacaagggc gtgcgcaagg tgacaccggg cgatgtcgaa ctttgggtgg gcggcggcca
     5761 gccggtttcg cgaccgggcc tgcctgcggt ggcgggaacg aaggcgcggg tgcgggtgac
     5821 cggaacccgc acactgccgc gctgaaagcg gccgctcgga acccctccgg gttccgggcg
     5881 tccaacccgc atgaacttcg aaatcgcgca tctcgggctc gtcgatgaag agctgatcgc
     5941 gcccgagatc gccgcgctgg agcttgccgc tctcgatcat cccggagtcg agctcgatcc
     6001 ctatttcgac atcctttccg aaattgccga agagctcgcg gacgtcgggg ccggcgcggc
     6061 gagcgcgccc gaacaggcgc tggcgctcgc cgaagtgatc ggcgccagct acgaattcga
     6121 cggcgatcgc gagaagtatg acgatcgcca gaatgtcgac atgatccggg tcatcgaccg
     6181 ccgtcgcgga atgcccatca gcctctcgat cctctatgtc ggccttgcga ggcggatcgg
     6241 ctggcccgcc gacgccctca acacgcccgg ccatgtgttg gttcggatcg gccccgatac
     6301 cgcccccctg ctgatcgacc cgttcaatgg cggcaccatc gtcaacgccg accgcctcac
     6361 cacccttctc tcgcacgtgc tcggcgccga cgtgagcccg tccgccgagc atctcgcgcc
     6421 gatgtcgaac cggtcgatgc tggttcgcct gctgatgaac gaggcgacgc gcgccgaagc
     6481 cgccggcgat ccggagcgtg ccctcgtcct gttcgagcga atgaccgtag tcgcgcccgc
     6541 caacagccat gcctggtggg agaaggcccg gctcgaactg gtcggcaacg acgcctcggc
     6601 cgcccgggga agcctcagtg ccctcctcga aatgactcgc gacccgaaca tgcgcggcca
     6661 catcagcgcg atgctcgatt cgctggcacg gccgagcacc tgagccgcga caccggcgat
     6721 tacttgcgtc cgatctcgcg ccagtccgtc tcgcttacct cgactccgaa cttcgccgct
     6781 gccgtcctga tccttttcca ggccgcatca cggtccgcat cgctgacgcc cttcacctgg
     6841 ttgaaccgag cgatcgcatt gcgcacgtgg ctggcatttt ccagcggttc cttgcgcgtc
     6901 tcgggaaagg cgaaagcgcc cttcccgagg tggtcccgtt cgtccgcgct gagcttcgac
     6961 atggtctgct ctgtccgacg tgtggaggaa atgagagtca ggccgtcgcg agcggcgcgt
     7021 cggcagcttc gaccaggttg atgaattccc gggtgaaagc ggggatgtca tccggcttgc
     7081 ggctggtgac gagattgccg tcgcgggcga cttcctggtc gacgacgttc gcgccggcgt
     7141 tcctgaggtc ggttcgaatc gaaggccagc tggtcagcgt gcgcccgcgg atcacgtcgg
     7201 cctcggccag aagtcacggg ccgtgacata tggcagcgac cggcttcccc gcctcgacga
     7261 attgccgcac catcgagatg acggcctgct cggtgcgcaa tttgtcgggg ttcttggttc
     7321 ctccgggcag gagcagggcg tcgaacgcgc caccgtcgac atcgccgatc tccacgtccg
     7381 gcgcgatccg cgcacccttg tcgccctcga tctcgtcgcg ggacagcgaa gcaagcgtca
     7441 ccgccgcacc tttctgcttc agcgtgttca atgggtccat aagctccgaa tcctcgaagc
     7501 cgttggtggc gatgatcagt atcctggcgt cggaaatgtc gggcatggcg cttcgtcctc
     7561 gaacagggtc gggcgcttca accggcgagc gtgcctcccg ttccgaggag gagatggagc
     7621 gatgcgctca cggcaggaga agcgacgcat ccccgtacga gtagaagcgg tatcctccct
     7681 tgattgcatg cgcataagcg gcttgcatcg tctcccgccc catcaaagcc gaaaccagca
     7741 tgaacagcgt cgatcgcggc agatggaagt tggtgagcag gccgccgatc gcgcggaagc
     7801 ggtagcccgg cgtgatgaag atcgcggtat cgccctcgaa cgggcggacg atgccgtcct
     7861 cgccggtggc gctttcgagc aggcggagcg acgtcgtccc caccgcgatg atccgcccgc
     7921 cttcggcccg cgcggcgttg agccgctcgg cggcggcggc gtcgatccgg ccccattcgc
     7981 tgtgcatgcg atgatcgtcg gtgtcgtcgg ccttgaccgg caggaaagtg ccggcgccga
     8041 cgtgcagggt gagcgtttcg tgggcgatgc cgcgccggcc gagcgcgtcg atcagcgcgg
     8101 gcgtgaagtg gagtgcggcc gtcggcgcgg cgactgcccc tttctcgcgc gcgaacatcg
     8161 tctggtaatc ttcgacgtcg cgggcgtcgg cctcgcgcct ggcggcgatg tacggcggca
     8221 gcggcatccg gcccgcccgt tcgagcagga gctcgaccgg ctcttcgccg tcgaaggaga
     8281 gcaggatcga tccgtcttcg gccttttccc ccgcaagcgc ggtgactccc gcgccgaaat
     8341 cgatccggtc gccgtcgcgc acccgttttg cgttgcggac gaaggcccgc cagtcgcgca
     8401 gcccttcccg cttgtggagc gtcgcgccga tccgggcatc gccgcgccgc ccttcgagct
     8461 gggcgggaat caccctggtg tcgttgaaga ccagaacgtc gccgggccgc agtagctgcg
     8521 gcaggtccgc gacactatgg tcggcgaggc catcgggacg gaccagcaga agccgcgcgc
     8581 tgtcgcgcgg ttccgccggc cttagtgcaa tccgctcggg cggaagctcg aaatcgaaga
     8641 gatcgacgcg cacattattg ctgcttgggg gtgccttgtg caggcgccgg ctgcgcctcg
     8701 gtcgccggtg cgggcgcggg cgccgcggca ccgccctgaa tcggcagcaa ggtcggcccg
     8761 gcgggcgccg ccggctggtg cgccgccatc accgcggcga cctcggccgg cgtcggcggc
     8821 gcgacattgt cggcgccgat cgacgccttg atgatccgcg acgggttcat cggcggctcg
     8881 ccgcgctcga tcgcatcgac atagttcata cccgatacca cccggccgaa caccgtatat
     8941 ttgttgtcga ggctgaagcg cggcgcgaac atgatgaaga actggctgtt ggcggtgtcc
     9001 ggcgcgtcgg tgcgggcggc ggaaaccgcg ccccggacgt gcggcagcgc gttgaactcg
     9061 gccttgagat ccggaagatc ggaaccgccg ctgccgtcgc ccttggggtc gccgccctgc
     9121 gccatgaagc cgtcgatgac gcggtgaaaa gccaggccgt tatagaagcc ccggcggacg
     9181 agcgtcttgt accgctcgac atggccgggc gcgacgtccg gccgcagctg aatggtaaca
     9241 cggcccccgg tcgacagatc gagcaccaga gtgttttccg gatcgagcgg cggcggcacg
     9301 aacggcgttg ccgccggttg ctgcgcggcc agcgcgctcg caaagaaaaa gcccatcaac
     9361 agggcgataa gtgccttgat acgcatgaat ttcattttcc ccgggtgtct cgcattgtgc
     9421 cgctgggggc ggcgaggatc aagagccttt gcggccgagc ttctcgaccc gcgcggcgac
     9481 gtccaccgca acgcacgcag tcacgaactt gccgatgtcc ccaccataga gcgcgatctc
     9541 cttaaccagc cgtgacgcga tcggctgcag cgacacgtcc gccatcagaa acacggtctc
     9601 gatgtccgcg ttcagctgct ggttcatacc cgccatctga tactcatact cgaagtcggc
     9661 gacggcgcgc aggccgcgaa cgatcatcga ggcgccctgc cgctcggcga aatccatcag
     9721 cagggagtcg aacgagacca ccgagatggc gccatccatg tcggcaagct cgcgccgcac
     9781 catcgcgatc cgctcctcca ccgtgaacat cggcgacttg gacggattgg tggtcactcc
     9841 gatgaccagg cgatcgacga gtttcgcgcc gcggcggatg atatcgatat ggccgagcgt
     9901 gatcggatcg aacgtgcccg gatagacgcc tattctcatg gttcctcccg ctgcaccgcg
     9961 gtgatctagc cggatctgcg cgatttgtcg aaggccggcg tcagtgatcg cgttcgaccg
    10021 cgaagcgggc gatcgcccgc agcaggtccg cctcggcgcc gtagctcgcc agatattcga
    10081 tcccttgcga gaccagcagc ttcgcctgct gacgggcgcg gtcgcgtccg agcagggtga
    10141 cgaacgtttc cttgccctgg tcgcgatcct tgccgacctt cttgccgatc ttctcctcct
    10201 cgccttcctc gtcgagcaga tcgtcggcga tctggaaggc gagcccgaca tcgcgggcat
    10261 agccgcgcag cttggtgcgg ccttccggcg gcacccggcc catgatcgcc cctgcttcga
    10321 gacagaagcc gatcaacgcg ccggtcttca gctgttggag acgggtgacg gcgctgagat
    10381 cgagcgcgct ctcggcggcg accatgtcca tcatctgccc gccggccatg cccgacggcc
    10441 ccgcggcacg ggcgagttcg ccgatcagct cggagcggac aaacgggtct tcgtgggtcg
    10501 cctcgtcgcc caggatctcg aaagcgagcg catgcaggct gtcgccggcg agcaccgcgg
    10561 tcgcctcgtc ataggccttg tgcagggtcg gcttgccgcg gcggatgtcg tcgtcgtcca
    10621 tgcacggcag atcgtcgtgg atcagcgagt agacgtggat cgcctcgacc gcggcgccga
    10681 cccgcagcgc ccgctgccgg tcgacatgga acaggcctgc cgatgcggtg acgagcaggg
    10741 gccgcagcct cttgccagcg cccattgccg catagcgcat cgcctcgaac aagcgcgcac
    10801 gcggatcggg cggcaccgcc agcagagcat cgaacagggt gtcgatctcc gaccggatcc
    10861 ggtcgaatgc cggcgcgagg aggctgtcgg ccatggcggg agtctcaggc cggatcgaac
    10921 ggcgcggtgc ccgccggctg accgtcgcgg ccgatctgga tcttctcgat ccgggcctgc
    10981 gccgcctgca gccgtgcctc gcattgctgc cggagccgat cgccctcgcc ataaagctgg
    11041 atcgactcgt cgagcgaggc gtcgccgctc tccaggcggc gtacgatctc ctcgagccgc
    11101 ttcagcgcgg cttcgaagga gagttcggaa atggcgtcat tctggtcgga catggcgcag
    11161 agcattggcg gcggcatttc ctccggtcaa cccggcgccg cttgacgcgc gcggtccttc
    11221 gccggagcat ccggtctcgg ccttctcggc gcacagaaga cggagtgaag atggcgcacg
    11281 atccggatcc ggcgatgatg gcggcgcccg aagcgctcgc gcgtttcctc gagacccgaa
    11341 atgaagcgat gctgtggagc gtgttttccg acagcgacga cgtgaccatc ctcgaaaact
    11401 tcccgccgca tctgtttcga ggacgcgcgg gcgtaagccg ctggcgcgag ttgatggccg
    11461 aacatgtcgg caaactggag cagctccgcc atgccttcgg tccggcgcag gattatggcg
    11521 agacggagga ccaggccttc ttcaccctgc cgacagcctg gaccggcctg cgcgacggca
    11581 tgccgttcac cgagcatggc ggctggtcgt tcctaatggc gcgtgaggag caaggctggc
    11641 ggatccgcgc ttatgcctgg gcggtgacca gcttcacctg atcgccgtcg ccgccagccc
    11701 tccgctcatg gttctgccgc gtacaaaccg tggtgtgtga ggatgaacaa tgtgcgtccg
    11761 ccagcgccac cgaacagcag ttgcagcggc cgttcgggca cgtcgatccg gcccgcctcg
    11821 cggccgtcgg cagtgaagac gaagatctgg ccgttggcga catagacccg cccgttcgcg
    11881 ccggtggcga cgctctcgcc gccccggctg gcgaagggct tgagatcggt cagcgcgccc
    11941 ccggcgccga gcagggcact ataggtgcga tcctccgagc tgttgctgac gaacacgcgg
    12001 tcgcccacct tgccgccgac gaagccatag gtgtcgagcg tgtccgagaa gcgccagccg
    12061 aggaaattgc tcggcccctg ctgccagact cggaacgcgg gcagagcgac gctgccgtcg
    12121 ggcgacacat attcgcgggg cttgggcgtc gccgcatcgc gggcgaacat ctcggcgagg
    12181 gtggtgaagc gatcgcgggc cggatcatat tgatcgcgga actcgccatt gttccagaag
    12241 ctggcgggca gcgcgatctg ccgctcggcc ttgggcgaga ccggcgtcgg cgcgattacc
    12301 gtcaccttat ccggcctgtc gggatcgatg ctgtagacgc tcgcctccgg cccgtcggaa
    12361 gacaggacca gcagatcgcc ggaacggtcg acggcgagat taaccggatc gagaggggcg
    12421 tcggcgacga tcgacagccc ttgatcctcc gaccagccgt ggatgcgctg gaacgggcga
    12481 tcgatgaaat agagcttgcc cgcgccgtcc accgcgccgc cgccgaggga ggcgaagccg
    12541 ccaccgagct tgcgcaccgg caccaggcta ggtgtcgcag gcggcggcgg cgccgcggcg
    12601 acgtcgagac gcgcgaattc gcgctcgcgc acctccaggc cgctggtcat gtcctggatc
    12661 gcattctcgt acggatattt gctcgcccgc aaataggtgc cgcagccatt tgcgtcacag
    12721 gtggcgaagc cgctctccgc attgacgtgg acattgcgga agcggatgtc ggtcgaattg
    12781 tagagccgca ccgcggccgg tgccggctgc agcgatcgtg tgactcggta gccgtgataa
    12841 ttggcgaaca ggatgtcgcg cgaattgcgc acttccagcg acaccgcgtt gcggctctcc
    12901 cccgcttctt cctcggtctg cggcgccagg aattcccaat tgcgaacgcc gtcgagcacg
    12961 atctcggcgc gggcatggtg ctcggccgac atctcgtaga cgaagccggg cgtgctggtg
    13021 ttcgacacga acatgcccga ttgggcgaag gtgttgggcg tccacagatt gttgaaggtg
    13081 ccgccgccgc cgtcggtcac ccacaagctg ctatattgcc cgtcccagcg cttgcgcgga
    13141 tcgggatcgg cggtgtgatt ggcgttgtac ggatcgatgc ggctgccgtc ggcggcgttg
    13201 gtgccgtgcc cgccgaggaa gcggacgtcg tcgaccagcg acgtttcgcc ggcccgccac
    13261 agcagcgcgg tcgcgcgcgg gttgatcccg ccggtgtcga ggccgagccc ggagacgatc
    13321 gccgtgccgc ctttggcgct ctcgagcagc gcccgtgggc tgccgatgcc gcgataggcc
    13381 gggctgtcgt cggcaagcgt gatccgggtg aggctcgggt gcaggccgat cagcacgctg
    13441 tcgggacgca gggtcagccg gtcgctgacc cgataaaaac cggccgggaa atagagcacc
    13501 cggtgggtgt cgatcgcgcg ctggagggcc gcagtgtcgt cgctgctgcc gtcccccttg
    13561 atgccgagat cgcggacgtt cgcccatgaa gccgtccccg gcaatgcgcg gatcgcaggg
    13621 gcgcggcggg cgggcagcgc gcgcagcggc gcagcgtcca tccgggtctc gaagcggccg
    13681 gtctggccga tcgccggcac cgtcaggcca taggtgaatt ccttgacgcg gtagcgggcc
    13741 gccggccccg ccaccgtcct gccgctgtca cggaagcgcg cgaacaccgg cgtgccgctc
    13801 gccaccgcat tgtcgaagcc gacctgggtg taggcgttgc cctcgttgct gatgatcacg
    13861 ccggcgcggg cgacattctc gaagcggacg tccttgcccc acagccagtc gccatagcct
    13921 tcgtcgattt cgatgccgac ggggacgttg cggaaccgtg tgttgacgag ggtgagcccg
    13981 gcttcgtgct cgcggatcgc ggcatcgcgc tggccgtcga actcggaatc gagcaacgta
    14041 tattgccagg ccgccgaggg cttctcggtg aggatcccat agcggccgcc gaagaagcga
    14101 agatcctgcc cgacattgcc ggcctggtag atgccggcga gcgcagatcc caggcggaag
    14161 tcgatgtggc tgaggaaggc gtgctgggcg gtgtggaagc gcaccgccgt cgccgccgga
    14221 ttgccttcgc cgatctcgaa atcgacgttg gacagggccg agtagaaggt gccgctattg
    14281 gcgtcggcga tttcggggtt gaacggcacg ctggtcggcg gcggcaccgg cacccgcgcc
    14341 ggcgcgacca cgccccccgg cccgggcgcg gcgccgcccg ggcgattgcc ggtgaagaac
    14401 agcatcgatc cgacgccctg ctggaaaccg ggcgtggccg ccccgagcag gatggtaggc
    14461 cgagtcttgc cggtgccgaa cacgcgcacg cccggccaga cgaagatcgt cctgccgatc
    14521 cggtatcggc ccgacggcag gaagacgatg ccgccgccgc ctttcgcttc ggccgcgttg
    14581 atcgccgcct ggatcgccgc gccgtcgtcc gccttgccgt cgccgacggc attgacggtc
    14641 accgcgcgcg gatcggcggg aatggcggtg aagctcgagg gcggtgcggc aagcgctggc
    14701 aacgcggcgc ccgcgagcag caaggcggcg atcagtctgg gagtcacgaa ccggttactc
    14761 tgcgctgttg atgggacggg aataggactt gcggcgtcga ccggccactc cgaccatggt
    14821 cgtaatggcc agatcggccg ccgggccgat agggacgaac cgggctgcga aggctcggac
    14881 gatctggggg attgggtgca gccaccgcac ggaagaagag atttgccgcc gctcgccatc
    14941 gtcgtcatgg gcgtcagcgg ctgcggcaag tcgacgctgg gcgcacgcct tgccgcagaa
    15001 ttcgattgcc cgttcctcga aggcgacagc taccaccttc ccgaaagcgt cgcgaagatg
    15061 cgggccggcc agccgctcgg cgacgatgat cgctggccgt ggctcgaccg cctcggcgct
    15121 gccgccggag acgccttgcg cgcggacggg atgagcgtgg tcgcctgctc ggcgctgaag
    15181 cgtgtctacc gggagcggct cgcctgcgcc gccagggcgc cgatgcgctt cgtgctgctc
    15241 gaagccgaac ccgccgaact catccgacgc ctcgggcagc gccccgaaca ttatatgccg
    15301 gccagtctgc tcgacagcca gttcgcgatc ctcgaacgcc ccggcgccga cgaagccgcc
    15361 ttgaccctcg acgccgcgct gccgcccgaa cgcctcgccg agcgggtgac tgcctgggcc
    15421 cggaccgaga tcgccgcgca ctcgctttag ggcatcagtc gcttgcggcc ctgcgacagg
    15481 tgccagcgca tcgccagggc ggcgccgtcg ccgtcctggg cgcggatcgc atcgacgatc
    15541 gcgtcatgct cgcccatcat cgccgcgatc acctccggcg gccgcgcccg cgaaatgtcg
    15601 actccggcct tgaggatctt ctcgacctcg tcatgcagat ggtcgaagat cgagacgaag
    15661 gcggtgttgg cggtggcttc ggcgatcgcg cggtggagaa gccaatcctc ctcgtgcgcg
    15721 ggcgcgctgg acagcaaggc ggcgcgcaga tcggcgagat ggccctcgat gcaggccagc
    15781 tgctcgctcg accggcgctg cgccgccagc cgcgccgcct ccgcctccag cacgaaacgc
    15841 acttcatagg tgccgagagt cgcggcgagc tccgccatcg gcatgtgcgc gccgagccgc
    15901 tccgacggcc gccgcttgac gtaggagcca gcgccacggc gcgcctccgt gatgccgtcc
    15961 gaggcgagcc gcaccagcgc ctcgcgcacg atcgtccgcg acatcccgaa catttcggcg
    16021 agccgcgatt ccgacggcag ccggtcgccg gcggcaagat tgtcgtcgtt gatgatctgg
    16081 acgatgcctg tataggcgcg gtccgccagc ctgccctcgt tcatcggcag catgcgcgtc
    16141 gcggcgtgtt cgaagacctg accatcaccc gacaaaatag ctcgctgcca tcaccatggc
    16201 gagcccgacc acggagatgg cggtttcgag catcgaccag gtgcggaacg tgtcgggcgt
    16261 gctggtgccg agatagccct tgaccagcca gaagccggga tcgttgacgt ggctgaagaa
    16321 gaccgatccg gcgccgatcg cgagcaccac cagctcgggc gaggcgccgc tcgcggccac
    16381 cacgccgggc atcacgccga cggcggtgat cgtcgccact gtcgccgatc cggtggcgag
    16441 ccggatcccg accgcgacca gccagccgag cagcaagggc gagattgcct gcagcgacgc
    16501 aaggcgggcg agcagatccg agagccctgc ggtcaccagc acctgcttca acgcaccgcc
    16561 ggcaccgatc gcgagcaggg tcgtgcccgc cgccgccatc gtctcggacc agatcgcgtc
    16621 ctggatcgtc gcatcgcgca gccgccgtcc gaacaggatc ggcagcgcga ccaggttggt
    16681 tatcagcaga gccatcaccg gattgctcgc ggccgcgagc caggcggagc ccgcaagcgc
    16741 cggcaccagc gggccgagcg cccccgcggc gatcagcacc acaggcagca gcacgatcag
    16801 cagcgcgaga tcgcgccgcg gcggggttcc gaccatcgcc ggtccctcga tcgcgggcgg
    16861 cgtcagccga acgccgcgtg cggtcaccag ggcgagcgcc gggccggcaa tagccgcggt
    16921 ggggatcgcg atcaggatgc catagagcat cgtcatgccc agatcggcgc cgatcgcctc
    16981 cactgccagc agcggaccgg gatgcggcgg gaccagggca tggaccaccg aaagaccggc
    17041 cagcgccggc agcatcagcc ccagtcgcgc ccggtccttg ccctcgccat ccggcagcgc
    17101 cgccgccgcc gccgcgacga tcggcagcag cagcaccagc ccggtttcga agaacagcgg
    17161 cagcccgatg acgatggcga tgccgaggct ggcccacggc gccgcccgcg gcccggtcag
    17221 ccgcaggccc gtggttgcga gcgccgctgc ggcgcccgac agctggagca tcgcacccag
    17281 cgacaggccg agcgcaacca ccagcccggt tccgccgagg atgtcgccga cccctttctg
    17341 taccgccttg gcggtgtcgg ccatcggcac gccggcgacc aggccgaccg tgaaggcgcc
    17401 gcagagcagg ccgacgaacg ggtggagccg gccgcgcacg atcagcagca cggcaagaaa
    17461 gatgccgcac agggcggccc cgaccagccg gaaatcgtcc gcgctcaccg gcgtatttct
    17521 ccttgcttca aggctttgct atgcggcacg accaatttcc tgagttccgc gaaacctgta
    17581 cgacaggttc gtagggtctc acaacaaaaa tgggcttgat tcaccctcga gggagggatc
    17641 atagtgctta cctgtccaac tgattccggg aaaagcggaa cgattggacc gacaatggac
    17701 cgccgggcgg catgttcgct cgtgcctggc ggtgcacccc ggctacggcc ggaggaggga
    17761 ggatgacatg caagggtttt ccgagtccgg tcccgctccg cagggcaatg tcgcggccat
    17821 cgccacgctc accccgaccc agttgaaggt gctgcacggc gttcattcgg gcctgctcaa
    17881 caagcagatc gcttatgatc tcggcatcgc cgaggcgacg gtgaaagcgc acatgacggc
    17941 gctgatgcgc aagctcaacg tccgcaaccg cacccaggtg gcgctcgccg cgcacgcgct
    18001 cacggcaagc aactgaggct cgcggcgacc gccctcacag ggcgatcgcg tacaaggcat
    18061 ggtggctgag gatgaacagg gttcgtccgt cggtcccgcc caccaccaat tgcaggggcc
    18121 gttccggcgt atcgatccgc cggatcaggc tgccgtccgg cgcgtagacg aagacctggc
    18181 cgttcgcgac atagacgttg cctgctgcgt ctcgcgcgac gctctcgccg ccccgctccg
    18241 caaacacctt gaggtcggtg aggctgccac cgtcgccgat gaggccgcta taggtcttgt
    18301 tctccgaacc gttggtaacg aacacccgct cgccggcctt cgccggcacg aggccgtagg
    18361 cgtcgagcgt gtccgaccag cgccagccga gatgatcgag cggcccctga ttccacacgc
    18421 ggaacgcggg cagcaccagc gagccgtcgg gcgagacata ttcctgcgtc ttgggacggc
    18481 cgatgtcgcg cgcgaacatc tcggccagag tggtgaattc gtaagttttg ggatcgagct
    18541 ggtcgcggaa ttcgccattg ttccagatgt tgaccggcag cagggtcgcg gcgtcgcggc
    18601 gcgctctcgt cggcgttggc gcgatcgcct tcacctccgc cggcaagtcg ggatcgatgc
    18661 tgtagacgct ggcgtcgggc ccggccgacg ccaggacgag caggtcgccg gagcgggcga
    18721 ccgccaggtt gatcgggtcg agcggcgcgt cggcgacgat ctccaagccc ttctcgcgcg
    18781 accagcggtg gatgcgctgg aagaagcgat cgatgaaata gagccggccc ttgtcgtccg
    18841 tcgccccgcc ggcgatcgaa tagaagccgt ccgccagctt ctcgacgccc ggcgtgatcg
    18901 ggatcgccgg tgcggtcgcc gcctgcgccg gcgccgccgg tacgtcgagc caggcgaatt
    18961 cgcgctcccg cacctcctgc tgacgggtca tgtccttgat cgcattctcg aacggatatt
    19021 tgctggcacg cgtgtaggtg ccgcagccct tggcatcgca gctggcaaag ccgctctccg
    19081 cattgacatg gacgttgcgg aaacggatcg cgcccgaatt gtagagtttc accgccgcat
    19141 ccatcggctt gatcgagcgg gtgacccggt agccgtgata attggcgaac aggatgttgc
    19201 gggaattgcg aatctcggtc gagatcgcgt cgacgccgtc gcgcacctcc tgctcggtct
    19261 gcggcgcgag gaactcccaa ttctcgactc catcgagcac gatctcggcc cggtaatgat
    19321 gctctgccga gagctggtag acgtaccctg gggtcttggt gtcggtgacg tggaagcccg
    19381 attgcgcgag cgtgttcggc gaccagatgg cggtgaaggt gccgccgcca ccgtcggtca
    19441 cccagatgct cggatgctgg ccgtcgaaat gggcgcgcgg atcgccatag ccgatcgggc
    19501 tgcccggccc gagcacggtg ccgccgccgc cctggatctt gacgtcgttg acctccgatt
    19561 tctcgccggc ccgccacagc aaggcggtgg cgcgggtatt gatgccgccg gtccacaggc
    19621 cgatgccgga gaccagggca ttgccgcctt tcgcactctc gatgagcgcc ttgggtccgc
    19681 cgactcccat ataggccggg gtctcgtcag gcaggtagat gtgagtgagg ctcggatgga
    19741 gcgagaccag caccgtgtcg ggtcgcagtt tcagcgtatc ggtcacccga tagcggccca
    19801 tcgggagata gatgactcgg tgggtgtcga tcgcgcgctg caacgccttg gtgtcgtccg
    19861 tggcgtcgtc gcccttggcg ccgagatcgc ggacattggc ccattgcgcc accggcggca
    19921 gcgtccggat cgcgggcgcg cgccgcgccg gcagcttgcc aaggggcgcc gcctgaaact
    19981 cggtcgcgta atcgccgacg gtgccgagcg cgggcagctt caggccatag ctgaagttcg
    20041 acacgcggta gctggcgccc ggcccagcca gagccttgcc gctgtcgcgg aagcgggcga
    20101 aggtcggcgt gccgcgtgcc agtgcattgt cgaagccgac ctgggtgaac acgctgccct
    20161 cgttgctgat caccaccccg gcgcgcgaca cgttctcgaa ccgcacgtcc ttgccccaca
    20221 gcgagtcgct gtaaccacgg tcgatctcga tcccgaccgg cacgttcttg atcgcgacgt
    20281 tgacgagggt gaggtcgacc tcatgctcac ggatcgcggc gtcgcgctgg ccgtcgaact
    20341 cggaatcaat cagagtgaac tgccaggccg gcgaggtctt ttcggagacg atgccgtagc
    20401 gaccgccgta gaagcgcaga ttctcgaatt cgttgccggc ctgatagacg ccggcgaagc
    20461 ccgagccgat gtggaaatcg atgtgcctga gatagccgtg ctgggcgacc cggaaacgca
    20521 ccgccgtggc gccggcattg ccgtcgccga tctcgaaatc gacgttggaa agcgccgaat
    20581 agaaagtgct cgatgttgcg tcgtagacgt tgggatcgaa cggcacgctg gtcggcggcg
    20641 gcaccgcgac cttgccgacc cgatactggt cctcgccggt gaagctcacc atggtcgcca
    20701 cacccgatcc gaagccgggc gtgttgtcgc cgagcaggat cacgggtcgg gtcttgccga
    20761 cgccgaagat ccgcaccgcc ggccgaacga agattgtccg cgatatccgg taacggccgg
    20821 agggcaggaa gacgatgccg ccatggccgc cctcggcggc gcggtcgatc gcccgctgca
    20881 gcgccgcact gtcg
//
