LOCUS       NZ_CP096889            21612 bp    DNA     circular CON 18-MAY-2024
DEFINITION  Bacillus cabrialesii strain TE3 chromosome, complete genome.
ACCESSION   NZ_CP096889
VERSION     NZ_CP096889.1
KEYWORDS    RefSeq.
SOURCE      Bacillus cabrialesii
  ORGANISM  Bacillus cabrialesii
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 4125766)
  AUTHORS   de Los Santos Villalobos,S., Robles,R.I., Parra Cota,F.I.,
            Larsen,J., Lozano,P. and Tiedje,J.M.
  TITLE     Bacillus cabrialesii sp. nov., an endophytic plant growth promoting
            bacterium isolated from wheat (Triticum turgidum subsp. durum) in
            the Yaqui Valley, Mexico
  JOURNAL   Int J Syst Evol Microbiol 69 (12), 3939-3945 (2019)
   PUBMED   31526457
REFERENCE   2  (bases 1 to 4125766)
  AUTHORS   Valenzuela Ruiz,V. and de los Santos Villalobos,S.
  TITLE     Whole genome sequence of Bacillus cabrialesii strain TE3(T) and
            endophytic biological control agent and plant growth promoting
            bacterium from wheat (Triticum turgidum subsp. durum) rhizosphere in
            the Yaqui Valley, Mexico
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 4125766)
  AUTHORS   de los Santos Villalobos,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-APR-2022) Microbiology, Instituto Tecnologico de
            Sonora, Calle 5 de Febrero 818, Urb. No. 1, Obregon, Sonora 85000,
            Mexico
REFERENCE   4  (bases 1 to 4125766)
  AUTHORS   de Los Santos Villalobos,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2018) Departamento de Ciencias del Agua y Medio
            Ambiente, Instituto Tecnologico de Sonora, 5 de Febrero 818 Sur,
            Obregon, Sonora 85000, Mexico
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 02-DEC-2021
            Assembly Method                   :: Unicycler v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology :: Illumina MiSeq; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004124315.2-RS_2024_05_18
            Annotation Date                   :: 05/18/2024 04:23:33
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,221
            CDSs (total)                      :: 4,100
            Genes (coding)                    :: 3,993
            CDSs (with protein)               :: 3,993
            Genes (RNA)                       :: 121
            rRNAs                             :: 10, 10, 10 (5S, 16S, 23S)
            complete rRNAs                    :: 10, 10, 10 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 107
            CDSs (without protein)            :: 107
            Pseudo Genes (ambiguous residues) :: 0 of 107
            Pseudo Genes (frameshifted)       :: 76 of 107
            Pseudo Genes (incomplete)         :: 46 of 107
            Pseudo Genes (internal stop)      :: 32 of 107
            Pseudo Genes (multiple problems)  :: 41 of 107
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:49:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3752263
            Orig. end                         :: 3773875
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP096889.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21612
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="sactipeptide"
                     /region_number="9"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     cand_cluster    1..21612
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21612
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11612](+)"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11612
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     misc_feature    complement(90..104)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 20.21"
                     /tool="antismash"
     gene            complement(182..3868)
                     /locus_tag="EFK13_RS19190"
                     /old_locus_tag="EFK13_19190"
     CDS             complement(182..3868)
                     /GO_component="GO:0009325 - nitrate reductase complex
                     [Evidence IEA]"
                     /GO_function="GO:0008940 - nitrate reductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009061 - anaerobic respiration [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1134: flavodoxin"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391609.2"
                     /locus_tag="EFK13_RS19190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EFK13_19190"
                     /product="nitrate reductase subunit alpha"
                     /protein_id="WP_129507296.1"
                     /transl_table=11
                     /translation="MKKKKMSPLFRRLNYFSPIEHHSNKHSQTTREDRDWENVYRNRWQ
                     YDKVVRSTHGVNCTGSCSWNIYVKNGIVTWEGQNLNYPSTGPDMPDFEPRGCPRGASFS
                     WYIYSPLRVKYPYVRGVLINLWREALQAHQNPLEAWKSIVENPEKAKSYKQARGKGGFV
                     RAEWPEVLKLISASLLYTVMKYGPDRNVGFSPIPAMSMISHASGSRFMSLIGGPMLSFY
                     DWYADLPPASPQIWGDQTDVPESSDWYNSGYIITWGSNVPLTRTPDAHFLAEARYKGAK
                     VISISPDFAESSKFADDWLSIRQGTDGALAMAMGHVILQEFYVNQETERFTEYAKQYTD
                     FPFLVTLSKENGVYTAGRFLHAKDIGRQTKNDQWKPAVWDEQTGAFAIPQGTMGSRWDG
                     QQKWNLHMIDEETGEPIEPRLSVLGIEDEIGTVRIPYFSNDGNKVLERDLPIKKLDLNG
                     EEVCVTTVFDLILANYGVNRGIGEQSAVSYDDPEPFTPGWQEQMTGIKKEAVIQIAREF
                     AQNAIDTDGRSMIIVGAGINHWFNSDTIYRAVLNLVLLVGAQGVNGGGWAHYVGQEKLR
                     PAEGWQTIANAKDWEGVPKLQNGTSFFYFATDQWRYEDQPISDLASPIAASSRYKHHAD
                     YNVLAARLGWLPSYPTFNKNGIDLYKEAERAGAATPKDVGAYVASQLQEKKLSFAIEDP
                     DNEANFPRNLFVWRANLISSSGKGHEYFLKHLLGTTNGLMNDDSDSIRPEEIKWREQAP
                     EGKLDLLINLDFRMAGTALYSDIVLPAATWYEKHDLSSTDMHPFIHPFAPAISAPWESK
                     SDWDIFKALSKAVSDLAEEVDMEPVKEVVATPLLHDTMQELAQPFGKINDWSKGECEAI
                     PGKTMPNIQVVERDYKHIFHKMTALGPYAGLKPSGTKGMSWSIADEYESLKKRLGEITS
                     DSVAKGCPNISEAKQAAEAILTLSSTSNGKVAVKAWESLENITNLKLKDLAEEREEECF
                     TFDQITAQPKTVITSPAFTGSEKGGRRYSPFTTNVEKLIPWRTLTGRQSYYVDHELMME
                     FGETMATFKPILQHRPFLSKRPDQEGKEIVLNYLTPHNKWSVHSMYFDSLPMLTLFRGG
                     PTVWMNKDDAEDTDIKDNDWIECFNRNGVVVARAVLSHRIPKGMAFMHHAQDRHINVPG
                     TKLTNNRGGTHNSPTRIHVKPTQMIGGYAQLSYGFNYYGPTGNQRDLNVVIRKLKEVDW
                     LED"
     misc_feature    complement(3934..3949)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     misc_feature    complement(3958..3971)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.07"
                     /tool="antismash"
     misc_feature    3958..3972
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.64"
                     /tool="antismash"
     gene            complement(4085..4561)
                     /gene="arfM"
                     /locus_tag="EFK13_RS19195"
                     /old_locus_tag="EFK13_19195"
     CDS             complement(4085..4561)
                     /codon_start=1
                     /gene="arfM"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391610.1"
                     /locus_tag="EFK13_RS19195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EFK13_19195"
                     /product="Crp/Fnr family transcriptional regulator ArfM"
                     /protein_id="WP_129507295.1"
                     /transl_table=11
                     /translation="MKQCDYLLFLKQLPMFNEVPLDIVETLLKNGIFIRGSSDQSPSFL
                     HSQSVYIVLKGSVRFMDSRLPEGSRTVALWEKGDVFPIDEKGGMYLSPFISVNATSDIL
                     ILNIPYYIFKKMMSYNPQLQMNFLAMLQQNVFCSYQLFLRYLHTSQDKNAEPGS"
     misc_feature    complement(4619..4634)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     gene            4705..5424
                     /locus_tag="EFK13_RS19200"
                     /old_locus_tag="EFK13_19200"
     CDS             4705..5424
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391611.1"
                     /locus_tag="EFK13_RS19200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EFK13_19200"
                     /product="YwiC-like family protein"
                     /protein_id="WP_129507294.1"
                     /transl_table=11
                     /translation="MKALIPKQHGAWAMLLIPFLLGMVKGGPVLWHIPLFLGWLFLYLA
                     VYPVTLALKKKQLNPYQKWICYYGFPACCFLVISVFHKPPLIWAGVSLLPLFLIHMYFA
                     RQKNERALVNDIAGVLFFCSGGLASCWLGTGTLDGWAWFIFSQSALFFIGSSFYVKSVI
                     RERKNRGFAYWSWGYHLLLPFLSALFGAGWAFLAFIPSSLRAWFFHGRDWPVKTIGILE
                     IVNACFFFAVMCMFITR"
     gene            complement(5456..6172)
                     /gene="fnr"
                     /locus_tag="EFK13_RS19205"
                     /old_locus_tag="EFK13_19205"
     CDS             complement(5456..6172)
                     /codon_start=1
                     /gene="fnr"
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391612.1"
                     /locus_tag="EFK13_RS19205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EFK13_19205"
                     /product="fumarate/nitrate reduction transcriptional
                     regulator Fnr"
                     /protein_id="WP_075748519.1"
                     /transl_table=11
                     /translation="MNFLSVRPSDSDFLSSGLYELLESISTKRKMEKHTYLFREGMDAE
                     ELYLIQSGLIEIGKLTSDGKDLTLRICQKNDIVGELTLFTEEPRYMLSAKVLEDGEVLV
                     INKNKLEKELIQNGALTFEFMKWMSTHLRKIQSKIRDLLLHGKKGALYSTLIRLSNSYG
                     VERSDGILINIVLTNQDLAKFCAAARESVNRMLGDLRKQGVISIDESGKIILHKRDYLR
                     CEIECENCPLEICNID"
     gene            complement(6272..7459)
                     /gene="narK"
                     /locus_tag="EFK13_RS19210"
                     /old_locus_tag="EFK13_19210"
     CDS             complement(6272..7459)
                     /codon_start=1
                     /gene="narK"
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391613.2"
                     /locus_tag="EFK13_RS19210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EFK13_19210"
                     /product="nitrate transporter NarK"
                     /protein_id="WP_129507293.1"
                     /transl_table=11
                     /translation="MFNRQHIQLSLQSLSLVAGFMVWVLISSLISQITLDIHLSKGEIS
                     LVTAIPVILGSLLRIPLGYLTNRFGARLMFMISFILLLFPVFWISIADSLFDLIAGGFF
                     LGIGGAVFSIGVTSLPKYYPKEKHGVVNGIYGAGNIGTAITTFAAPVIAQAAGWKATVQ
                     MYLVLLAVFALLHVLFGDRHEKKVNVSVKTQIKAVYRNHVLWFLSLFYFITFGAFVAFT
                     IYLPNFLVEHFGLNPADAGLRTAGFIAVSTLLRPAGGFLADKMSPLRILMFVFAGLTLS
                     GIILSFSPTIGLYTFGTLTVAVCSGIGNGTVFKLVPFYFSKQAGIANGIVSAMGGLGGF
                     FPPLILASVFQTTGQYAIGFMALSEVALASFVLVIWMYWQERMKTHTERNSQSVN"
     misc_feature    complement(7523..7538)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     gene            complement(7592..9262)
                     /gene="argS"
                     /locus_tag="EFK13_RS19215"
                     /old_locus_tag="EFK13_19215"
     CDS             complement(7592..9262)
                     /EC_number="6.1.1.19"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="argS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391614.1"
                     /locus_tag="EFK13_RS19215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EFK13_19215"
                     /product="arginine--tRNA ligase"
                     /protein_id="WP_129507292.1"
                     /transl_table=11
                     /translation="MNIAEQMKDVLKEEIKAAVLKAGLAEESQIPHVVLETPKDKTHGD
                     YSTNMAMQLARIAKKAPRQIAEEIVASFDKGKASIEKLDIAGPGFINFYMNNQYLTKLI
                     PTVLEAGDAYGETNIGNGERVQVEFVSANPTGDLHLGHARGAAVGDSLCNVLSKAGYDV
                     SREYYINDAGNQINNLALSVEVRYFEALGLEKPMPEDGYRGEDIIAIGKRLAEEYGDRF
                     VNEEESERLAFFREYGLKYELEKLRKDLENFRVPFDVWYSETSLYQNGKIDTALEALRE
                     KGHVYEEDGATWFRSTTFGDDKDRVLIKKDGTYTYLLPDIAYHKDKLDRGFDKLVNVWG
                     ADHHGYIPRMKAAIEALGYEKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIEE
                     VGLDAVRYFFAMRSADTHMDFDLDLAVSTSNENPVYYAQYAHARICSMLRQGEEQGLKP
                     AADFDFSHIQSEKEYDLLKTIGGFPEAVAEAAEKRIPHRVTNYIYDLASALHSFYNAEK
                     VIDPENKEKSRARLALMKATQITLNNALQLIGVSAPEKM"
     gene            complement(9259..9687)
                     /locus_tag="EFK13_RS19220"
                     /old_locus_tag="EFK13_19220"
     CDS             complement(9259..9687)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391615.1"
                     /locus_tag="EFK13_RS19220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EFK13_19220"
                     /product="DUF1934 domain-containing protein"
                     /protein_id="WP_129507291.1"
                     /transl_table=11
                     /translation="MKQETPITLHVKSVIEDDGNQEVIEFRTTGFYYVKQNKVYLSYYE
                     EHDLGKVKTIVKVSEGEVLVMRSGAVKMNQRFVTGASTIAKYIMSFGELELKTSTKSIQ
                     SDLDEEKGRISIAYDMHVGDEQQHLHNMTITYEGGTHA"
     misc_feature    9867..9881
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.54"
                     /tool="antismash"
     misc_feature    9893..9908
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.53"
                     /tool="antismash"
     gene            10001..10132
                     /gene="sboA"
                     /locus_tag="EFK13_RS19225"
                     /old_locus_tag="EFK13_19225"
     CDS             10001..10132
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="sboA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: Subtilosin_A"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391616.1"
                     /locus_tag="EFK13_RS19225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EFK13_19225"
                     /product="subtilosin A"
                     /protein_id="WP_003222002.1"
                     /sec_met_domain="Subtilosin_A (E-value: 8.9e-29, bitscore:
                     97.4, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKAVIVENKGCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
     CDS_motif       10001..10030
                     /prepeptide="leader"
                     /note="peptide class: sactipeptide"
                     /note="predicted sequence: MKKAVIVENK"
                     /locus_tag="EFK13_RS19225_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       10031..10132
                     /prepeptide="core"
                     /locus_tag="EFK13_RS19225_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="33.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKAVIVENK"
                     /leader_location="[10000:10030](+)"
     misc_feature    10169..10183
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 20.93"
                     /tool="antismash"
     misc_feature    complement(10171..10187)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 24.97"
                     /tool="antismash"
     misc_feature    10187..10200
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.7"
                     /tool="antismash"
     gene            10266..11612
                     /gene="albA"
                     /locus_tag="EFK13_RS19235"
                     /old_locus_tag="EFK13_19235"
     CDS             10266..11612
                     /codon_start=1
                     /gene="albA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Subtilosin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391617.1"
                     /locus_tag="EFK13_RS19235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EFK13_19235"
                     /product="subtilosin maturase AlbA"
                     /protein_id="WP_129507289.1"
                     /sec_met_domain="subtilosin (E-value: 0.0, bitscore:
                     1075.8, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="Subtilosin_rSAM_RRE (E-value: 2.2e-29,
                     bitscore: 99.6, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 9.7e-07, bitscore: 26.9,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 1.9e-44, bitscore:
                     150.0, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 4.1e-06, bitscore: 24.3,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.3e-21, bitscore: 75.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 5.1e-10, bitscore:
                     37.5, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.6e-09, bitscore: 36.0,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFIEQMFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLN
                     KTAYELCMRMDGQKTAAQILAEQCAVYDESPEDHKDWYYDMLNMLLNKQVIQLGNQAGR
                     HTITTSGSNEFPMPLHATFELTHRCNLKCAHCYLESSPEALGTVSIEQFKKTADMLFDN
                     GVLTCEITGGEIFVHPNANEILDYVCKRFKKVAVLTNGTLMRKESLELLKTYKQKIIVG
                     ISLDSVNSEVHDSFRGRKGSFAQTCKTIKLLSDHGIFVRVAMSVFEKNMWEIHDMAQKV
                     RDLGAKAFSYNWVDDFGRGRDIVHPTKDAEQHRKFMEYEQNVIDEFSDLIPIIPYERKR
                     AANCGAGWKSIVISPFGEVRPCALFPKEFSLGNIFHDSYESIFNSPLVHKLWQAQAPRF
                     SEHCMKDKCPFSGYCGGCYLKGLNSNKYHRKNICSWAKNEQLEDVVQLI"
     aSDomain        10281..10556
                     /aSDomain="Subtilosin_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a subtilosin
                     sactipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_EFK13_RS19235_Subtilosin_rSAM_RRE.1"
                     /evalue="1.50E-31"
                     /identifier="RREFam018.1"
                     /label="EFK13_RS19235"
                     /locus_tag="EFK13_RS19235"
                     /protein_end="97"
                     /protein_start="5"
                     /score="99.6"
                     /tool="antismash"
                     /translation="MFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLNKTAYE
                     LCMRMDGQKTAAQILAEQCAVYDESPEDHKDWYYDMLNMLLNKQVIQ"
     gene            11625..11786
                     /gene="albB"
                     /locus_tag="EFK13_RS19240"
                     /old_locus_tag="EFK13_19240"
     CDS             11625..11786
                     /codon_start=1
                     /gene="albB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391618.1"
                     /locus_tag="EFK13_RS19240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EFK13_19240"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbB"
                     /protein_id="WP_003222006.1"
                     /transl_table=11
                     /translation="MSPAQRRILLYILSFIFVIGAVVYFVKSDYLFTLIFIAIAILFGM
                     RARKADSR"
     gene            11783..12502
                     /locus_tag="EFK13_RS19245"
                     /old_locus_tag="EFK13_19245"
     CDS             11783..12502
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391619.1"
                     /locus_tag="EFK13_RS19245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EFK13_19245"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_129507288.1"
                     /transl_table=11
                     /translation="MSILDIHDVSVWYERDNVILEHVDLHLEKGAVYGLLGVNGAGKTT
                     LINTLTGVNRNFSGRFTLCGIEANAGMTQKTSDQLKIQRYFAADYPLLFTEITAKDYVS
                     FVHSLYQKDFSEQQFASLAEAFHFSKYINRRISELSLGNRQKVVLMTGLLLRAPLFILD
                     EPLVGLDVESIEVFYEKMREYCEEGGTILFSSHLLDVVQRFCDYAAILHNKQIQKVIPI
                     GEETDLRREFFEVIGHE"
     gene            12495..13805
                     /gene="albD"
                     /locus_tag="EFK13_RS19250"
                     /old_locus_tag="EFK13_19250"
     CDS             12495..13805
                     /codon_start=1
                     /gene="albD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391620.1"
                     /locus_tag="EFK13_RS19250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EFK13_19250"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbD"
                     /protein_id="WP_129507287.1"
                     /transl_table=11
                     /translation="MNNLFPIMSLLFKQLYSRQGKKDAIRIAAGLVILAVFEIGLIRQA
                     GIDESVLGKTYIILALLLMNTYMVFLSVTSQWKESYMKLSCLLPISSRSFWLAQSVVLF
                     VDTCLRRTLFFFILPLFLFGNGTLSGAQTLYWLGRFSFFTIYSIMFGVVLSNHFVKKKN
                     WMFLLHAAVFACVCLSAAFAPAITIPLCAVHMIWAVMIDFPVFLQAPPQQSKMHSFLRR
                     SAFSFYKREWNRFITSKAMLLNYAVMAAFSGFFSFQMMNTGIFNQQVIYIVISALLLIC
                     SPIALLYSIEKNDRMLLITLPIKRRTMFWAKYRFYSGLLAGGFLLVAVIVGFISGRPIS
                     ALTFVQCMELLLAGAFIRLTADEKRPSFSWQTEQQLWSGFSKYRSYLFCLPLFLATLAG
                     TAVSLAVIPIAGLIIVYYLQKQDGGFFDTSKRERLGS"
     gene            13795..14955
                     /locus_tag="EFK13_RS19255"
                     /old_locus_tag="EFK13_19255"
     CDS             13795..14955
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391621.1"
                     /locus_tag="EFK13_RS19255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EFK13_19255"
                     /product="insulinase family protein"
                     /protein_id="WP_129507367.1"
                     /sec_met_domain="Peptidase_M16_C (E-value: 2.2e-05,
                     bitscore: 22.5, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVNLLKTDQFSTISIAASFLKPIECAAEPEEETIYFYGAAAHLK
                     QQIIDAFGYAAGSRFMYSANLFFDRHLKTCGTRLIHPSCNKNLHVDALMKTFADMSFPP
                     SLSADAVEKAKDELLLKIEKKLADPFSYSAARLAEEAFGNPMYGTAMFGRKDRIQAIHP
                     QRFLDAADFIVDLLSQHKQLNILGQIQACDIPGQASQASTVTAGRILVNRHVFVTETRS
                     AAGPSVLTLGFDCGQMKDASDYIKIQLIDGLLGKYGHSALFKHFREKDLAVYHVITRYD
                     VMNNLLLVSICTDQLHEKEVPPRVLEAVSHFQTNERELEQAKQFLRNEMLLQFDSPEGL
                     LAYMGILRCFSCTKEDLLDGISAVTCRDVLEFIATISYIGAHVVRG"
     gene            14960..16243
                     /locus_tag="EFK13_RS19260"
                     /old_locus_tag="EFK13_19260"
     CDS             14960..16243
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391622.1"
                     /locus_tag="EFK13_RS19260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EFK13_19260"
                     /product="pitrilysin family protein"
                     /protein_id="WP_129507286.1"
                     /sec_met_domain="Peptidase_M16 (E-value: 9.6e-14, bitscore:
                     49.5, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKKAFFQHLDEQTDIKYTDSGLKIFRLKFPRAHLRLCNVKIDFG
                     SRDVCLQAESGDTLLPYGTAHFLEHLLFWHNGRNLYSDFFAHGALLNAFTTYTDTNFMF
                     TSLPDRLRQTIPILLDALWNHSFDKKMITQEKAVITSEIQTAHLNHQLSYHYQLINMLS
                     PASPAAVFPAGRTKDIEALDIRALQKAYKAAYQPQRMTLFLIGGSEDTETLLPSHQRLE
                     KHPVHKTTERKIISACPPIASPKKVLGEEERMEDTWTGLQIGALPGQNDLLTVKLYWDI
                     ASRILFQLDSPFFQEIQQTYRLEIDRLSAEAHIYEDGGFLILHSQGTHSSAYIDVASYY
                     VTQQKKQIADWLQYGKDSLTDAIIYDSDYVRKCFEWAAECDRCNCSFLDIYGIIHEMNS
                     QDFLSLIDALASSNKAVIHVSQKEAIVQ"
     gene            16240..16941
                     /locus_tag="EFK13_RS19265"
                     /old_locus_tag="EFK13_19265"
     CDS             16240..16941
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015250988.1"
                     /locus_tag="EFK13_RS19265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EFK13_19265"
                     /product="bacteriocin biosynthesis protein AlbG"
                     /protein_id="WP_129507285.1"
                     /transl_table=11
                     /translation="MRKSTMFTLLLLLAGMAAYSFGWVQAVAKAAAQYVQIIDNDVARL
                     GLLACIASVLMLPAFLYLRYVTQSVKNMTAAFQKLTQSHQSCCDFQQHRLCSRYAEDVK
                     SLRDSYKNVRQTYVMTAVLCQVIIFGCMFEIVKAVPFRLHTPPAVSMGLAVLLILYLLF
                     YMRTYLLQLFQHGTLFRKVLVGALTGAGIWWMLSFTISELLFLIIVATIQQIGSSIYKH
                     ISDRRPASFEL"
     gene            complement(17079..18434)
                     /locus_tag="EFK13_RS19270"
                     /old_locus_tag="EFK13_19270"
     CDS             complement(17079..18434)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391625.1"
                     /locus_tag="EFK13_RS19270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EFK13_19270"
                     /product="YncE family protein"
                     /protein_id="WP_129507284.1"
                     /transl_table=11
                     /translation="MRKNKLSFKEKAKAAQEECLCFCEEEASREAMFQAPIELPEGFVV
                     DPAEAVANVAWNADSLSCVIERCLIETGPEPDAIDVQFAVRLQGTVTLLVSVSPVRNQY
                     GQGNGAVSVIHSAEIDQVVYYSDEPDDCPDFSDITIENLVVVPPFYGSPLSVTGTIVLV
                     PEPEPVYAFTANPNDQSVSVIDTNTHTVVTTIALPYRPTGIEITPDGSAVFVLHFNNNM
                     ISVIDYDTLTVTATIILDQPPQSIKFIPNHEFAYVLGDTVIYVIGIDTLVVDRSIPVEG
                     FDFAIDPNGLFAYVLNFGLVQKVDLFTGEVTGTIERELIVSSIETDSPERYAYVLEQEF
                     LFNYLTVIDLNTFTISDTQELEPDGQYRMFTSGTDVYLHDSFTGNLYFVSPNGAGVIGN
                     VPQSARDFAFTPNGEFLYATHFLEQNITVYNTDDYSVETVISLGVSPGAITI"
     misc_feature    18614..18630
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 22.81"
                     /tool="antismash"
     gene            18663..19808
                     /locus_tag="EFK13_RS19275"
                     /old_locus_tag="EFK13_19275"
     CDS             18663..19808
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391626.1"
                     /locus_tag="EFK13_RS19275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EFK13_19275"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_129507283.1"
                     /transl_table=11
                     /translation="MTGVISSSSVGEKINEWYMYIRRFSIPDAEYLRREIKQELDQMEE
                     DQDLHLYYSLMEFRHNLMLEYLEPLEKMRIEEQPRLSDLLLEIDKKQARLTGVLDYYFN
                     FFRGMYELDRREYVLAIQFFKKAESKLIFVKDKIDKAEFFFKMSEVYYYMKQTYVSMDY
                     ARQAFEIYSEQTTYDIRMIQCQSLFGANFLDLKQYEKAIAHFQKAFTLAEAEQQPQLMG
                     RTLYNIALCKQNQNSFESAIEYVKKSIRVFERSKMLPSLPQAFFLITQIYFKLGKMDNA
                     CEYHKKGKEYSAAAGDTVYLTEFEFLESLYLSGPDEERIEKCFVFLESKMMYADIEDFA
                     LDVAKYYHQQENYKKASHYFLKVEEARQHIQGGVNLYEMEV"
     gene            19792..19911
                     /locus_tag="EFK13_RS19280"
                     /old_locus_tag="EFK13_19280"
     CDS             19792..19911
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003326489.1"
                     /locus_tag="EFK13_RS19280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EFK13_19280"
                     /product="PhrC/PhrF family phosphatase-inhibitory
                     pheromone"
                     /protein_id="WP_129507282.1"
                     /transl_table=11
                     /translation="MKWKYKLLLACLAVSAVFITIEVSNSSTEHFDVAQRAMI"
     gene            19991..20398
                     /locus_tag="EFK13_RS19285"
                     /old_locus_tag="EFK13_19285"
                     /pseudo=""
     CDS             19991..20398
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003227547.1"
                     /locus_tag="EFK13_RS19285"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="EFK13_19285"
                     /product="YbaK/EbsC family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSLGRVKTHFEQWNREQDAMAFETSCATVEQAAETIGVTPARLLR
                     RCPSEEKEIRRF"
     misc_feature    complement(20806..20822)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 22.61"
                     /tool="antismash"
     misc_feature    20880..20896
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 21.78"
                     /tool="antismash"
ORIGIN
        1 gcctttatat ttgtcctggt cctcccattg cttggggtag ccgatgcccg gctttgtttc
       61 tacattatta aagtacatat attccgcacc ggaacggttt gtccacgtat ttttgcaggt
      121 aacgctgcac gtgtggcagc cgatgcattt atccaagttc atgaccatac cgatttgcgc
      181 tttaatcttc aagccaatcg acctccttca gcttgcggat gacgacattc aggtcgcgct
      241 gattccctgt tggaccgtaa tagttaaagc cgtagctgag ctgggcatag cccccgatca
      301 tctgtgtcgg cttgacgtga atccttgtcg ggctgttgtg ggtgcctccg cggttattcg
      361 tcagttttgt gccgggcacg ttgatgtggc ggtcctgggc atggtgcata aacgccattc
      421 ctttaggaat ccggtgggac aaaaccgctc tcgcgacgac aacaccgttt cggttgaagc
      481 attcaatcca atcgttgtct ttgatatccg tgtcctctgc gtcatcttta ttcatccaca
      541 cggtcggtcc gccgcggaac agcgtcagca tcggcaggga atcaaaatac atgctgtgga
      601 cggaccattt attgtgcggc gtcaaataat taaggacgat ttctttgccc tcttgatcag
      661 gccgcttgct taggaacgga cgatgctgga ggatcggttt aaatgtcgcc atcgtttcac
      721 cgaattccat catcagttca tgatcgacat aataagattg tctgccggtc agtgttcgcc
      781 acgggattaa tttttctacg ttcgtcgtaa acggcgagta cctgcgccct cctttttccg
      841 agccggtaaa tgccggagac gtgatgaccg ttttcggctg agctgtaatt tggtcgaacg
      901 taaagcattc ttcctcccgt tcttccgcca ggtctttcag cttcaggttt gtgatgtttt
      961 caagcgattc ccaagctttc acggcgactt ttccatttga agtggacgat agggttaaaa
     1021 tcgcttctgc cgcctgcttc gcttcactta tattcggaca tccctttgcg acgctgtccg
     1081 aggtgatttc tcccaatctc tttttgagtg attcatattc atcggctatc gaccagctca
     1141 ttccttttgt tccgctcggt tttaaaccgg cgtaaggccc gagcgcggtc attttatgaa
     1201 agatatgctt gtaatcccgt tcaacgactt ggatgttcgg catcgttttt cccggaatgg
     1261 cttcacattc gcctttgctc cagtcattga ttttgccgaa cggctgggcc aactcctgca
     1321 tcgtgtcgtg gaggagcggc gtcgcgacca cttctttcac cggctccata tcgacttctt
     1381 ccgccagatc ggaaacggct ttagacagag ccttgaaaat atcccagtct gacttcgatt
     1441 cccacggagc cgaaatagcc ggagcaaaag gatgaatgaa cgggtgcata tccgtgctgc
     1501 tgagatcgtg tttttcatac catgtcgccg ccggcagcac gatatcggaa tacagcgccg
     1561 tacccgccat tcgaaaatca agattgatta ataagtcgag cttcccttcc ggcgcctgct
     1621 cccgccattt gatttcttca gggcggatgc tgtcgctgtc gtcattcatc aaaccgttcg
     1681 tcgtccccaa aagatgctta agaaaatatt catgcccttt tcctgagctg gagatcagat
     1741 ttgcccgcca tacgaagaga ttccttggaa aattggcttc attgtcggga tcttcaatcg
     1801 cgaatgacag ttttttctct tgaagctgtg aggccacgta cgcaccgacg tctttcggtg
     1861 ttgccgcccc cgctctttca gcttccttgt atagatcaat gccgttttta ttgaatgtcg
     1921 ggtaggacgg cagccaccct aaccgcgccg ccagcacatt gtaatcggcg tgatgcttgt
     1981 agcgggagga cgctgcgatc ggtgaagcca agtcactgat cggctggtct tcgtaacgcc
     2041 actggtctgt cgcaaagtag aaaaacgagg tgccgttttg cagcttgggc acaccctccc
     2101 aatcctttgc attggcaatc gtctgccatc cttcagcagg acggagcttt tcctgcccca
     2161 cgtaatgagc ccagcctccg ccgtttacgc cttgggcgcc taccagcaaa acaagattta
     2221 acaccgcgcg gtagattgtg tcggagttga accagtggtt gatccccgcc cctacgataa
     2281 tcatggaccg gccgtctgta tcgatcgcat tttgagcgaa ctctctggca atctgaataa
     2341 cggcttcttt tttgattcct gtcatctgtt cctgccagcc aggcgtaaac ggctcagggt
     2401 catcataaga gacagcggat tgttcaccga taccccggtt cactccgtag ttggccagta
     2461 tcaagtcaaa cacggttgtg acacatactt cttcaccgtt caggtccagt tttttaatag
     2521 gaagatcccg ctcaagcact ttatttccgt catttgaaaa atacggaatg cgcaccgtac
     2581 cgatttcgtc ctctattccg agcacagaga gacggggttc aatcggctct ccggtttctt
     2641 catcaatcat atgcaggttc catttctgct gcccgtccca gcgggagccc attgtccctt
     2701 gcggtatggc aaacgcgcct gtctgttcat cccagaccgc aggcttccat tgatcatttt
     2761 ttgtctgccg cccgatgtcc tttgcatgca gaaaccgccc tgctgtgtat acgccatttt
     2821 cttttgacag agtgacgagg aatggaaaat cggtgtattg cttcgcgtac tcagtgaaac
     2881 gttccgtctc ttgattcacg taaaactcct gcaaaatgac gtgacccatt gccatcgcaa
     2941 gcgctccgtc agtcccttgg cggatactca gccagtcatc cgcgaacttt gaggattccg
     3001 caaaatccgg actgatcgaa atgaccttag cccctttata gcgggcctcc gccaaaaagt
     3061 gcgcgtcagg ggttctcgtt aacggaacgt tggagcccca tgtgatgata tagcctgaat
     3121 tgtaccaatc actgctttcc ggtacgtccg tctggtcacc ccaaatttgc ggggacgccg
     3181 gcggaagatc cgcataccag tcataaaaac tgagcatagg gccgccgatt aacgacataa
     3241 accgtgagcc tgatgcgtgg ctgatcatgg acatggccgg aataggagaa aagccgacat
     3301 tccggtcagg cccgtatttc atgactgtat acagcagaga ggctgaaatc agcttcagca
     3361 cctccggcca ttcagcgcgg acaaaaccgc ctttccctct tgcctgttta taggacttcg
     3421 ctttttcagg gttttcaacg attgatttcc aggcttcgag cggattttga tgagcctgca
     3481 atgcttcccg ccacaaattg atcagcacac cgcgcacgta tgggtatttc acacgaagcg
     3541 gactgtagat ataccatgaa aaactggccc cccgcggaca gcctctcggt tcgaaatcag
     3601 gcatatccgg gcctgttgat gggtaattca agttttgtcc ttcccacgtg acaattccgt
     3661 ttttcacata aatattccag ctgcaagacc ctgtgcagtt gacgccgtgg gtggagcgaa
     3721 cgactttgtc gtactgccat ctgtttctgt atacattctc ccaatcgcga tcttcgcggg
     3781 tggtttggct gtgtttatta gaatggtgtt ctataggaga gaaatagttc aatctcctaa
     3841 acaacggact cattttcttt ttcttcataa gagttcactc cttccgagtc aggtgatgct
     3901 aaattcacta taaacagaga cagcgcgttc ccttgtgaac tatgtcacac actctgcttt
     3961 tttcacaaaa tgttcacaaa aaggagaagg aaggattttc acaggatgtg atgaaggggc
     4021 attcaggcag gacgcctgag tcattagccg ccttccattc aaagatcaaa aaaaccggct
     4081 ctatttaaga gccgggctcg gcgtttttat cctgtgatgt atgcaggtac cgcaaaaata
     4141 attgatagga acaaaagaca ttttgctgaa gcatggccaa aaagttcatt tgcagctgcg
     4201 gattgtaaga catcattttt ttaaatatgt aataagggat attgagaatc agaatgtctg
     4261 aagtggcatt gactgagata aaaggcgata aatacatccc gcctttttca tcaatcggaa
     4321 acacatcgcc tttttcccac agcgcaacgg ttctcgaccc ttcagggagc ctgctgtcca
     4381 taaaacggac actacctttt aatacaatat aaacggattg agaatgaaga aaggatggag
     4441 actgatcaga tgaaccgcgg ataaatattc cgtttttcag caaggtttcg acaatgtcta
     4501 gaggcacttc attaaacata ggaagttgtt tcagaaataa taaatagtca cattgtttca
     4561 taggaaagcc tcctgtgcta aggatagctt tagtgtagct cgattgagcc tgtacagcag
     4621 tgatgtattt cacagcttgt atgatgaatg tcacttaccg gaagaatggc tacatttata
     4681 atgaaataaa aaaggaggat ttcgatgaag gcgctgattc cgaagcagca cggcgcatgg
     4741 gcaatgctgc tgattccatt tttactcggg atggtcaagg gcggtcccgt tctctggcat
     4801 attccgctct tccttggctg gcttttccta tacttggcgg tttatcccgt tacgctcgcc
     4861 ttgaaaaaga aacaactcaa cccctatcaa aagtggatat gttattacgg ttttccggcc
     4921 tgctgctttt tggtcatttc tgtttttcat aagccgccgc tcatctgggc tggcgtttct
     4981 ttattgccgc tgtttctcat tcatatgtat tttgcccgcc aaaaaaacga acgggcccta
     5041 gtgaatgata tcgcgggagt cttgttcttt tgttcgggcg ggcttgcgag ctgctggctg
     5101 gggacgggaa cccttgacgg ctgggcttgg tttatttttt cccaatccgc tttatttttt
     5161 attgggagtt ccttttatgt gaagtcggtg atccgggaga gaaaaaacag agggtttgca
     5221 tactggtcat ggggatatca cctgctgctc ccctttttat ccgctctttt cggagcagga
     5281 tgggcgtttc tcgcttttat cccgagcagc ttgcgggcat ggttttttca tggaagggat
     5341 tggcccgtaa aaacgatcgg tattctagaa atcgtgaatg cctgcttctt ttttgccgtc
     5401 atgtgcatgt ttatcacaag ataaaaaaca aggacatcgc tgtccttgtt ttttttcagt
     5461 caatattgca aatctccagc gggcaatttt cacactcgat ctcacatcgt aaatagtccc
     5521 gcttgtgcaa aataattttt ccggattcgt ctatcgaaat aaccccttgt ttgcggagat
     5581 ctcctaacat acggttgacg ctttcccttg ccgccgcgca aaactttgcc aagtcctgat
     5641 ttgtcagcac aatattaatc agaatgccgt cgcttcgttc caccccgtag ctgtttgata
     5701 agcggataag ggtcgagtag agcgctccct ttttgccatg aagcagcaga tccctgattt
     5761 tggactggat tttccggagg tgggtgctca tccatttcat aaattcaaat gtcaaagcac
     5821 cgttttggat taattccttt tccagcttgt ttttattaat gacgagcacc tcgccatcct
     5881 ccagcacttt tgcactgagc atatatcttg gctcttcagt gaaaagtgtt aattccccga
     5941 caatatcgtt tttttggcag attctaagcg tcaggtcttt tccgtcagac gtcagcttgc
     6001 cgatttcaat gagtcctgat tgaatcagat aaagctcttc cgcatccatt ccttcccgaa
     6061 acaaatacgt gtgtttttcc atttttcttt tcgtgctgat tgattccagc aattcataca
     6121 gaccactgga aagaaagtca ctatcagatg gtcgaacaga gagaaaattc atgagctcac
     6181 ctcgaagaaa gtcacgttgc gtatgtttat tgtaacgtga attaatttgt acccatcgag
     6241 aaaaaactaa caatcttgtg aatgcccgtt gtcagttgac gctctgactg tttctctccg
     6301 tgtgcgtttt cattctttcc tgccaataca tccatatgac aaggacaaag ctggctaatg
     6361 caacttccga aagtgccata aaaccgatcg cgtattggcc cgttgtctga aagacactcg
     6421 ccaaaatcag cggagggaaa aatccgccta atccgcccat ggcagacaca ataccatttg
     6481 caatccccgc ttgcttcgaa aagtagaaag gcaccaattt aaaaacagtc ccgtttccta
     6541 tacctgagca gaccgccacc gttaatgtcc cgaacgtata aaggccgatc gtcggcgaga
     6601 acgacaagat tatgcctgat aatgtaagtc ccgcaaatac aaacatcaag atgcgaagcg
     6661 gactcatttt atcagccagg aatccgcccg ctggcctgag cagcgtggag acggcaataa
     6721 agccagccgt ccgcaaaccg gcgtccgcgg gattcagccc aaagtgctcc accagaaagt
     6781 tcggcagata gatggtgaag gcgacaaagg cgccaaatgt aataaaataa aacaggctca
     6841 gaaaccatag cacatgattt cgataaacgg ctttgatttg agtttttacg gaaacattca
     6901 ctttcttctc atgccggtcg ccgaacaata cgtgcagcaa tgcgaaaact gccagcaata
     6961 ctaaatacat ctgtacagtt gctttccatc ccgcagcttg agcgataacc ggcgccgcaa
     7021 atgtggtaat ggcggttccg atgtttccgg ccccgtaaat tccattgacg acaccgtgct
     7081 tttctttcgg ataatatttc ggaagggatg tcaccccgat ggagaatacc gctcctccga
     7141 tccctaagaa aaaaccgcct gcgattaaat caaacagaga atccgcaata ctgatccaaa
     7201 acacaggaaa taaaagcaga atgaagctga tcataaacat cagccttgct ccaaacctgt
     7261 tcgttaaata ccctaaagga atgcggagaa gcgacccgag gatcacggga atcgccgtca
     7321 ccaaagaaat ctcgcccttg cttaaatgaa tatctaatgt gatttgggaa atgagtgatg
     7381 aaatcagcac ccacaccata aaccctgcca ccaagcttaa tgactgtaac gataattgaa
     7441 tgtgttgacg gttgaacatt cggcttgccc ctttcaatga ttcaatatca gtcttatcat
     7501 acaaaaactc agcaaacagg attgtgaaat acatcacacg ttttacccat aaaaaaagag
     7561 caaagcccga agactttgcc cttcattatc attacatttt ttccggagcc gatacgccga
     7621 tcagctgaag cgcattgttc agcgtaattt gcgttgcttt cattaaagca agacgcgcgc
     7681 ggctcttctc tttattttct ggatcgatga ctttctccgc attgtagaag ctgtgcagag
     7741 cagaagccag atcataaata tagtttgtga cacggtgagg aattcgtttt tccgccgctt
     7801 ccgccaccgc ctccgggaat ccgccaatcg ttttcagcag gtcatattct ttttctgatt
     7861 gaatatgact gaaatcaaaa tccgccgccg gcttcagccc ctgctcttcc ccttggcgaa
     7921 gcatgctgca aatacgggca tgggcgtatt gtgcataata cacagggttt tcgttagatg
     7981 ttgatacagc aagatctaag tcaaaatcca tatgcgtgtc agcactgcgc atcgcgaaga
     8041 agtaacgcac ggcatccaag ccgacttctt caatcaggtc gcgcatcgtt accgctttac
     8101 ccgtccgttt gctcattttc attttctcgc cgtttttgta aaggtgtacg agctgaatga
     8161 tttctacttc aagtgttcct ttttcatagc caagcgcttc gatcgccgct ttcatgcgcg
     8221 ggatgtagcc gtggtgatcg gcgccccaaa cgttgaccag cttatcaaag ccgcggtcaa
     8281 gcttgtcctt atgatacgcg atatcaggaa gcaggtacgt gtacgtgccg tccttcttga
     8341 tcaatacgcg gtctttatca tcgccgaatg tcgtggagcg gaaccaagtc gcgccgtctt
     8401 cttcatagac atggcctttt tcgcggagcg cttcaagcgc cgtgtcaatt ttgccgtttt
     8461 ggtacagtga cgtttcggaa taccacacat caaacggcac acggaagttt tccaagtcct
     8521 tgcgcagctt ttccagctcg tatttcaggc cgtattcacg gaaaaatgcg aggcgttcgc
     8581 tttcctcttc gttgacgaaa cggtcgccgt attcctcagc gaggcgcttt ccgatcgcaa
     8641 tgatatcctc gccgcggtag ccatcctccg gcattggttt ttccaagccg agcgcttcaa
     8701 agtaacggac ctccacagaa agcgccagat tgttgatttg atttccggca tcgttaatgt
     8761 aatattcgcg gctcacatcg taaccggctt ttgaaagcac attacataag gaatcaccga
     8821 cagcagcacc gcgcgcatgc ccgaggtgaa ggtctcccgt tggattcgct gatacgaatt
     8881 cgacctgaac tcgttcgccg tttccgatgt tcgtttcccc gtatgcatct cccgcttcta
     8941 atacagtcgg gatcagcttc gttaaatatt gattgttcat atagaaattg ataaaacccg
     9001 ggccggcgat atcgagcttt tcaattgaag cctttccttt atcaaaagaa gcgacaatct
     9061 cctcagcgat ttggcgcggc gctttttttg cgattctagc tagctgcatc gccatatttg
     9121 ttgaataatc gccgtgtgtt ttatctttcg gtgtttctaa aacgacatgg ggaatttggc
     9181 tttcttcagc cagtcccgct ttcagaacgg ctgctttgat ttcttctttc agcacgtcct
     9241 tcatttgttc cgcaatgttc atgcgtgagt tcctccctca tacgtgatcg tcatattatg
     9301 taaatgctgc tgctcgtctc cgacatgcat gtcatatgcg atgctgattc ggcccttttc
     9361 ttcatcgaga tccgattgaa tcgattttgt gcttgttttc agctcaagct caccaaatga
     9421 cattatatat ttcgcaattg tggaagctcc cgttacgaaa cgctgattca ttttgacggc
     9481 gcctgacctc atgaccagca cttcgccttc gcttactttc acaatcgttt ttactttgcc
     9541 taagtcgtgt tcttcataat aagatagata cactttattt tgttttacat agtaaaatcc
     9601 ggtggtgcgg aattcgatga cttcctggtt tccgtcatcc tcgatcacag acttcacatg
     9661 gagtgttatc ggtgtctctt gcttcatttt gacacgtcct tttcatcatt ccactttgac
     9721 ttgaatagta taatcattca gtttgtaaac ttcaactgct tctatcttac catcattgct
     9781 catcagattt gaagataaac ctcataaaaa gcatttcctt aatagaagag aaaatcatat
     9841 cactaattgc ctttagggaa tgttacattt ttctgaaatc tatcttttca aattcacatt
     9901 ttcttcaaaa tatatgtatt gaaatggtaa tttgatagtt ttatgataaa agcacaacat
     9961 agatctgcta gaaaaaacaa aataaaggga ggattcaatt atgaaaaaag ctgtcattgt
    10021 agaaaacaaa ggttgtgcaa catgctcgat cggagccgct tgtctagtgg acggtcctat
    10081 ccctgatttt gaaattgccg gtgcaacagg tctattcggt ctatggggat aaggtctcca
    10141 aaaagggcat agtttttcta ctatgtcctt ttttaagtaa attacaattt ttaactaaat
    10201 tctacctctt ggttatacat acacaatcgt ttttcatttg aatcatatgt ataggggatg
    10261 gtattttgtt tatagagcag atgtttccat ttattaatga aagtgtaaga gttcaccagc
    10321 ttcctgaggg cggcgtgtta gaaatcgact acttgcgcga taatgtttcc atttctgact
    10381 ttgagtattt ggatcttaac aaaacggctt acgagctttg catgcgaatg gatgggcaaa
    10441 aaacggctgc acagatttta gccgagcaat gcgcagtgta tgatgaatca ccagaagacc
    10501 ataaggactg gtattatgac atgctcaaca tgctcctgaa caagcaggtc atccagcttg
    10561 gaaatcaggc tggccgccac acaatcacca cgagcggaag caatgaattt ccgatgccgc
    10621 tgcacgccac ctttgagctg acacaccgct gcaatttgaa atgcgcacac tgttatttgg
    10681 aaagctcgcc ggaagcgctc ggcaccgtgt cgattgagca atttaagaaa acggctgata
    10741 tgctgtttga caacggtgta ttgacatgcg aaatcacggg cggagaaatc tttgtccatc
    10801 cgaatgccaa tgagattctt gactatgtgt gcaaaaggtt caaaaaggtc gctgtcttaa
    10861 caaatggaac actcatgcga aaagagagcc tggagctatt gaaaacttat aagcaaaaaa
    10921 tcatcgtcgg catttctctc gatagtgtga attccgaggt ccatgactcc tttagaggga
    10981 gaaaaggctc ttttgcccaa acttgtaaaa cgataaaatt gttgagtgac cacggtatat
    11041 ttgtcagagt cgctatgtcc gttttcgaaa aaaacatgtg ggaaatccac gacatggccc
    11101 aaaaggttcg ggatctcggg gcgaaggcgt tctcttacaa ttgggttgat gatttcggaa
    11161 gaggcagaga tatcgtccac cccacaaaag atgccgagca gcaccgcaaa tttatggaat
    11221 acgagcaaaa tgtcattgat gagtttagcg atctgatccc gattattcct tatgagagaa
    11281 aacgcgcggc aaattgcggc gctggctgga agtccatcgt aatcagcccg ttcggtgaag
    11341 tccgtccgtg cgcgctcttt ccgaaggaat tttcattggg aaatattttt cacgattcat
    11401 atgaaagcat ctttaactcc cctctcgtcc ataaactgtg gcaagcgcag gcgccgcgct
    11461 tcagcgagca ttgcatgaaa gacaaatgtc cgttcagcgg ctattgcgga ggctgttact
    11521 taaaagggct gaactctaac aaatatcacc ggaaaaacat ttgctcttgg gcgaaaaatg
    11581 aacaattaga agacgtggtc cagcttattt aggagggaaa cgatttgtca ccagcacaaa
    11641 gaagaatttt actgtatatc ctttcattta tctttgtcat cggcgcagtc gtctattttg
    11701 tcaaaagcga ttatctgttt acgctgattt ttattgccat tgccattctt ttcgggatgc
    11761 gcgcgcggaa ggctgactcg cgatgagcat tttggatata cacgatgtat ccgtttggta
    11821 tgaacgggac aacgtcatct tagaacacgt ggatttacat ttagaaaaag gcgctgttta
    11881 cggattgctt ggggtaaacg gcgccggaaa aacaacattg attaatacgc tgacaggggt
    11941 caaccgcaat ttcagtgggc gctttacact gtgcggcatt gaagccaatg ccggcatgac
    12001 gcagaaaaca tcagatcagc tgaagattca acgttacttc gccgccgatt atccgctgct
    12061 gtttacagaa attacagcaa aggactatgt gtctttcgtc cattcgcttt atcaaaagga
    12121 tttttcagaa cagcagtttg ccagtttggc cgaggccttt catttttcca aatacatcaa
    12181 caggagaatt tcggagctgt ccttggggaa caggcaaaag gttgtgttga tgacaggctt
    12241 attgctgcgg gctcccctgt ttattttaga tgagccgctc gttggcttgg atgtggaatc
    12301 catcgaggtc ttttatgaga aaatgcgcga gtactgtgag gaaggcggaa ccattttatt
    12361 ttcttcccat ctgctcgatg tcgtgcaaag attttgtgat tatgcggcca ttcttcacaa
    12421 taaacagatc caaaaggtca ttccgattgg agaggagacc gatctgcggc gggaattttt
    12481 cgaggtgatc ggccatgaat aacctattcc ccatcatgtc tttgctgttc aagcagcttt
    12541 acagccggca agggaaaaag gacgccatcc gcattgccgc aggtcttgtg attctcgccg
    12601 tgtttgaaat cgggctgatc cgccaggccg gcattgacga atcagtgctg ggaaaaacgt
    12661 atatcatact tgcgcttctt ttgatgaaca catatatggt gtttctttcc gtgacatcac
    12721 aatggaagga atcctatatg aagctgagct gcctgctgcc gatttcttca cggagctttt
    12781 ggctcgccca gagtgtcgtt ctgtttgtcg acacgtgttt gagaagaacg ttattctttt
    12841 ttattttacc gttgttcttg tttggaaacg gaacactgtc aggggcgcaa acattgtatt
    12901 ggctcggcag attttcgttt tttactattt actcaattat gtttggagtt gtgctaagca
    12961 accatttcgt caaaaagaag aactggatgt ttctgctgca tgcggctgta ttcgcctgtg
    13021 tatgcctcag cgccgctttt gcgccagcca tcacgattcc gctatgcgcg gttcacatga
    13081 tatgggcagt gatgattgac tttcctgtct ttctgcaggc gcctccgcag cagagcaaga
    13141 tgcattcttt tttgcggaga tctgcgtttt cgttttataa aagagaatgg aaccgattta
    13201 ttacctctaa agcgatgctg ttaaattacg cggtaatggc ggcgttcagc ggcttctttt
    13261 cgttccagat gatgaacacc ggcatcttca atcagcaagt gatatatata gtcatttccg
    13321 cccttttgct gatctgctcg ccgatcgccc ttttgtactc gattgaaaaa aacgaccgga
    13381 tgctgctcat cacccttccg attaaacgga gaacgatgtt ttgggcgaaa tatcgctttt
    13441 attcaggcct attggcaggc ggatttctcc ttgtcgctgt cattgtgggc tttatcagcg
    13501 gccgcccgat ttcagccctc acttttgtgc agtgcatgga attgctgctg gcgggagcgt
    13561 ttatcaggtt aaccgcggat gaaaaaaggc cctctttcag ctggcagacg gagcagcagc
    13621 tatggagcgg tttctcaaaa taccggtctt acctattttg tcttcccctt ttcttagcca
    13681 cattagccgg caccgctgtc tccttggcgg ttattccgat tgccgggctg atcatagtct
    13741 attacctgca aaaacaggat ggtggtttct ttgatacaag caaaagagaa cggcttggaa
    13801 gttaacctgc tgaagacgga tcaattttca acaatctcaa tcgccgcgag ctttctgaag
    13861 ccaatcgaat gcgcggcgga gcctgaagaa gaaacaatct atttttacgg cgcggccgca
    13921 catctgaagc agcaaatcat cgacgctttc ggttatgcgg ccggcagccg cttcatgtat
    13981 tctgcgaatc tcttttttga ccggcacctg aaaacctgcg gaacccgttt aattcatccg
    14041 tcatgcaaca agaatcttca tgttgatgcc ctcatgaaga catttgcaga tatgtccttc
    14101 cctccttctc tttcagccga tgctgttgaa aaggcaaagg atgaactgct gctcaaaatc
    14161 gaaaagaaac ttgccgaccc gttctcctac tcggcagcac gcttggcgga agaggccttc
    14221 ggaaacccga tgtatggcac tgccatgttt ggccgaaaag acaggataca agcaatccac
    14281 cctcaacggt ttctagacgc agcggacttc atcgttgatt tattgtccca gcataaacag
    14341 ctgaacatat tgggacagat acaagcatgt gatattccgg gacaggcctc gcaagcatcc
    14401 accgtgacgg ccggtagaat acttgtgaac cggcatgttt ttgtaacaga gacacgcagc
    14461 gcagcaggcc cttccgtctt gacactcgga tttgactgcg ggcagatgaa agatgccagc
    14521 gattatatca aaatccagct gatagacggg ctgctcggaa agtacgggca ttccgcttta
    14581 ttcaagcatt tccgcgagaa ggatctggca gtctatcatg tcatcacccg ttatgacgtt
    14641 atgaacaatc tgctgcttgt ttcaatatgt acggatcagc ttcatgagaa ggaagttccc
    14701 ccgcgcgttt tggaagctgt ctcacatttt caaaccaatg agcgggaact ggaacaggca
    14761 aagcaatttt tacggaatga aatgctgctg caatttgatt ctcccgaggg gctcttggcc
    14821 tatatgggaa ttctgcgctg cttctcctgc acgaaagaag acttgctgga tgggatctcg
    14881 gcggttacat gccgggatgt attggaattc atagcgacta tcagttatat cggagctcat
    14941 gtagtaaggg gatgaagaga tggaaaagaa agcttttttt cagcatctgg atgaacaaac
    15001 cgatatcaaa tacacagaca gcgggctgaa aatattcaga ttgaaatttc cccgcgccca
    15061 tctgcggctg tgcaatgtga aaatcgattt cggaagccgt gatgtctgct tacaggcaga
    15121 atccggcgac acgctgctcc cgtatggcac agcgcatttt ttagagcacc ttctcttctg
    15181 gcataatggc cgcaatctgt acagtgattt ttttgcgcat ggcgcgcttt taaatgcgtt
    15241 caccacctac accgatacca atttcatgtt tacctcattg ccggatcggc tcagacagac
    15301 gatccccatc ctgcttgatg cgttatggaa ccactcattt gacaagaaaa tgatcactca
    15361 ggaaaaagct gtgattacaa gcgaaattca aacagcacac ctcaatcatc agctctctta
    15421 ccattatcag ctgatcaaca tgctttctcc cgcctcgcct gctgccgtct tccccgcggg
    15481 cagaaccaag gacattgagg cgctggacat ccgtgcttta caaaaagcct acaaggccgc
    15541 ctatcagccc cagcggatga cgctgttctt gatcggaggc tcagaagaca cggaaaccct
    15601 tttgccttct caccagcggc tggaaaaaca tccagttcat aaaacaacag aaagaaaaat
    15661 catttccgca tgtcctccaa tcgcctcacc aaaaaaggtg ctgggtgagg aggagcggat
    15721 ggaagacacg tggaccggac tgcagatcgg cgcacttccc gggcaaaatg atctgttgac
    15781 agtaaagctt tattgggaca tcgcgtctcg tattctattt caattagatt caccgttttt
    15841 tcaagagatt cagcaaacat accgtctgga aatcgatcga ttgtcagccg aggctcatat
    15901 ttatgaggat ggcggttttc tgatccttca cagccaaggg acgcattctt cggcttatat
    15961 cgatgtcgct tcctactatg tcacacagca gaaaaaacag attgcggact ggcttcaata
    16021 cggcaaggat tctttgacgg acgcaatcat ttatgacagc gattatgtgc gtaaatgctt
    16081 cgaatgggcg gccgagtgtg accggtgcaa ttgctcgttt ctcgacatat acggcatcat
    16141 tcacgaaatg aatagccagg atttcttgtc cctcattgac gcactggcat cttccaacaa
    16201 agcggttatt cacgtttctc agaaagaggc gattgtacaa tgagaaaaag cactatgttt
    16261 actttgttat tgctgctggc gggaatggcg gcttattcct tcggctgggt tcaggccgtc
    16321 gccaaagccg ctgcgcaata tgtacagatt attgacaatg atgttgcacg gctcggactg
    16381 ctggcttgta tcgcttccgt cctgatgctg cccgcttttc tctatcttcg ctatgtcacc
    16441 caatccgtga aaaacatgac agcagctttt cagaaactca cacagtctca tcaaagctgc
    16501 tgtgacttcc agcaacacag attgtgcagc cgctatgccg aagatgtcaa atcgctgcgt
    16561 gacagctata aaaacgtccg ccaaacatac gtgatgactg ctgtattatg ccaagtcatc
    16621 atattcggct gcatgttcga aatcgtcaaa gccgtccctt tccgccttca cacgccccct
    16681 gccgtttcaa tgggacttgc ggtgttgctg attttgtatt tactgtttta catgcgaacc
    16741 tacttgctgc agcttttcca gcacggcacc ctgttcagaa aagtgcttgt gggagccctc
    16801 acaggagccg gaatatggtg gatgctcagc tttaccataa gtgaactgct gtttctgatc
    16861 atcgtagcga cgatccagca gatcggatca tcaatctata agcacatctc tgatcgccgc
    16921 cccgcttctt ttgaactata aagcttctac atcgcaatcg cagacggacc tgtgccaacc
    16981 ggaatcatca ttacggctgg ataatcactc gtgcggtaca cggtcacggt attgtcgcca
    17041 cgctgtgccg catacatatc ctgattgtcc ggagttggtt aaatcgtaat ggcgcccggt
    17101 gaaaccccaa gagatatcac agtttccaca gaataatcat ccgtgttgta aacagtaatg
    17161 ttctgctcta aaaaatgagt tgcatacaga aattcgccat tcggagtaaa cgcaaagtct
    17221 cttgccgatt gtggaacatt tcctataacg cctgcaccat tcggacttac aaaatacaaa
    17281 ttgccagtga agctgtcatg taaatataca tctgttccgc tcgtaaacat tctatattgg
    17341 ccgtcaggct ccagttcttg ggtatcgctg atcgtaaacg tatttaagtc aataaccgtc
    17401 aaataattga ataagaattc ttgttctaag acatacgcat accgctccgg agaatctgtt
    17461 tctatggatg atacgataag ctctcgttca atcgttcctg tgacttcacc ggtgaatagg
    17521 tccacttttt gcactaaacc aaaattaaga acataggcga ataacccatt gggatcaatt
    17581 gcaaaatcaa acccttccac aggaatcgac ctatccacaa ctaacgtatc aattccaatc
    17641 acataaatca cagtatcgcc gagaacataa gcaaattcat gattagggat aaatttgatc
    17701 gattgtggcg gctgatcgag tataatggtt gctgttaccg ttaatgtgtc ataatcgatg
    17761 acagaaatca tattattgtt aaaatgcaag acaaacacag cgcttccatc cggagttatt
    17821 tcaatacctg tcggccggta cggaagagca atcgttgtca caacagtatg ggtgtttgta
    17881 tcaataacag aaactgattg atcatttgga ttcgctgtaa acgcataaac gggctccggc
    17941 tccggtacaa gcacaatcgt ccccgtcacc gataaaggac tgccgtaaaa cggcggaaca
    18001 acaacaaggt tctcaatcgt gatatcactg aaatccgggc aatcatccgg ttcatcagaa
    18061 taataaacaa cttgatcgat ctctgcactg tgaatgacag aaacagcccc gttcccttgt
    18121 ccatattgat ttcgcacagg tgagacgctg acaagaagcg taacggttcc ctgcaggcgt
    18181 actgcgaatt gaacatcgat tgcatcgggc tcaggccccg tctcaattaa gcagcgttca
    18241 atgacacaag aaaggctgtc tgcattccaa gccacgtttg caacagcttc agccggatca
    18301 acgacaaacc cctcaggcaa ttcaatcggc gcttgaaaca ttgcttcacg gctggcttct
    18361 tcctcgcaaa aacataaaca ttcttcttgt gcggcttttg ctttttcttt aaaggaaagc
    18421 ttattttttc tcataccttc acttcctttt cagaaataca ctgctcacgc agatacaaca
    18481 gaatatggaa ggtgaatctg tttgcttgta caaattgccg agggtaaaag cgggttttga
    18541 aaaaatcccc tccgatatgc ggtgtaacga aagaaaacat tgcggttttt ttgcgcttct
    18601 cacaagaatg atgatgataa aatatgacat atatagaata atgaagggag ggatttgcaa
    18661 acgtgacagg tgtcatatct tcttcttccg tcggagaaaa gattaacgaa tggtatatgt
    18721 acatacgccg attcagcata cccgatgcag aatatttgcg aagagaaatc aaacaagagc
    18781 tggatcaaat ggaagaagac caagatcttc atttgtacta ttcactgatg gaatttcggc
    18841 acaacctgat gcttgagtat cttgaaccgc tggaaaaaat gcggatcgag gaacagccga
    18901 gattgtctga tttactgctt gagattgata aaaaacaggc tcgtttaact ggagtccttg
    18961 attattactt taatttcttc aggggcatgt atgagctgga tcgccgtgaa tatgtattag
    19021 ccattcaatt ttttaagaaa gcagagagca aactgatttt tgtaaaagac aaaattgata
    19081 aagctgaatt ctttttcaaa atgtcagaag tctattacta tatgaaacaa acttatgtct
    19141 cgatggacta tgcacggcaa gcattcgaaa tatacagtga acagactaca tatgatatta
    19201 gaatgattca atgccagtcc ttattcggag ccaacttttt ggatttaaaa caatatgaga
    19261 aagcaattgc tcattttcaa aaagccttta cacttgccga ggcagagcag cagccgcaat
    19321 taatgggaag gacgctttat aacatagcgc tctgcaaaca aaaccaaaac agttttgaat
    19381 cagcgataga gtatgtaaaa aaatctattc gagtatttga aagatctaaa atgctccctt
    19441 ctctgccaca agcttttttc ctaattacac aaatttattt taaattaggt aagatggata
    19501 acgcttgtga atatcataaa aaaggaaaag aatattcagc agctgcggga gatactgtgt
    19561 acttaacaga gtttgaattt ttggaatctt tatacttgtc tggaccggat gaggaacgaa
    19621 tagaaaaatg ttttgttttc cttgaaagta aaatgatgta tgctgatatt gaagacttcg
    19681 cacttgatgt agctaaatat tatcatcaac aggaaaatta caaaaaagca tctcattact
    19741 ttttaaaggt tgaagaagca agacagcaca ttcaaggggg ggtgaattta tatgaaatgg
    19801 aagtataaat tattactcgc ttgtttagct gtgagtgctg tatttatcac aatcgaagta
    19861 tcaaattcat caacagaaca ttttgatgtt gcacaacgcg ccatgatcta aaaccgccga
    19921 ctttcggcgg tttttttctc ccctcttgcc agtcttccat gccttgtcgt gggagaggat
    19981 ggccagtatt atgtctctgg gtcgtgtgaa aacccacttt gaacagtgga atcgggaaca
    20041 ggatgccatg gcgtttgaaa catcatgcgc gacagttgaa caggccgctg agacgatcgg
    20101 cgtgactccg gcgaggttgc taagacgctg tccttcagaa gagaaggaga tcaggcgatt
    20161 ctgattgtgg ccgccggcga tgccaagatt gacaacaaat agttttgact ttaaagcaag
    20221 aatgctctct cctgactagg tgctgaagca tacaggtctt gaaactggag gcgtatgccc
    20281 gtttggattg gctcatgatc tggaaatttg tcttgatgta tcggtgaagc ggtttgaaac
    20341 tgtttttccg ggcacgtgca gcagaaactc tgctattgaa ctgacattga aaaaatgagt
    20401 tgatgttcgg aaaggctggg aataaaaaac atccagacaa cgggactgac cccataagat
    20461 gagacaaata aaaacacctt caagtttgaa aacggatgat tgttatccga aattagactt
    20521 gggggtgttt tttctatggg gacaagagtg agttatccgg ttgaagtgaa acagaaggct
    20581 gtagaaatga gattggcagg cgtacctatg aaagagatca tgcaggagtt gaatattaag
    20641 aataagacac agattcagac atgggttaga tggtacaagg ctggtgatac acatcgattc
    20701 gaacagcctg ttggaaagca atacacttac ggaaaaggtc cagagtattc ttccgaatta
    20761 gagaaactgc aggcagagaa ccgttacctg agacaacaga atgaagtgtt aaaaaagtac
    20821 aacgaattgg aaaggaagtt gatagcgaaa cgtcagtcga acttgtagaa gtattgtgca
    20881 gcacaatgac cgtgcaggat atctgtattc atttaggtat ctctcgagcg tcttattatc
    20941 gttggaagaa gaatcggatg aaggatcatc ccaagcgaca tttggaaaaa caaatcggta
    21001 cgttgtgccg agagcacaag tatcgatatg gatatcggaa aatcacagcc attttaaaaa
    21061 agggaatgcg tatcaaccat aaaacggttc aacgtattat gcagaaaaat cagtggcagt
    21121 gccgggttaa ggtgaaaaag cgtaagaaga atgggcagcc atatgccgta gtcgataata
    21181 tattggatcg gaactttcag tctgatcgcc ctcttgaaaa actagtaacg gacatcacat
    21241 atttgcctta tggacagaaa caattgtacc tttccagtat attagattta tacaatggag
    21301 aagtgattgc ttatacgatt ggcgataagc aggacacaga ctttgtctta gacacacttg
    21361 agcagctgcc aacattgcct gagaactgcg tgttacatag cgaccaaggt tctgtgtata
    21421 catcctacga gtatcaaaaa gctgttaaca caaaaggcat tatcatgagc atgtcccgca
    21481 aagggacgcc cgctgataat gcctccatcg aatcgtttca ttccttacta aagtctgaaa
    21541 cgttctatct taacagcatt gatcgaacta cgaccgccat cgtagaacgc actgtcacag
    21601 aatacattca tt
//
