LOCUS       NZ_CP096889            20409 bp    DNA     circular CON 18-MAY-2024
DEFINITION  Bacillus cabrialesii strain TE3 chromosome, complete genome.
ACCESSION   NZ_CP096889
VERSION     NZ_CP096889.1
KEYWORDS    RefSeq.
SOURCE      Bacillus cabrialesii
  ORGANISM  Bacillus cabrialesii
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 4125766)
  AUTHORS   de Los Santos Villalobos,S., Robles,R.I., Parra Cota,F.I.,
            Larsen,J., Lozano,P. and Tiedje,J.M.
  TITLE     Bacillus cabrialesii sp. nov., an endophytic plant growth promoting
            bacterium isolated from wheat (Triticum turgidum subsp. durum) in
            the Yaqui Valley, Mexico
  JOURNAL   Int J Syst Evol Microbiol 69 (12), 3939-3945 (2019)
   PUBMED   31526457
REFERENCE   2  (bases 1 to 4125766)
  AUTHORS   Valenzuela Ruiz,V. and de los Santos Villalobos,S.
  TITLE     Whole genome sequence of Bacillus cabrialesii strain TE3(T) and
            endophytic biological control agent and plant growth promoting
            bacterium from wheat (Triticum turgidum subsp. durum) rhizosphere in
            the Yaqui Valley, Mexico
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 4125766)
  AUTHORS   de los Santos Villalobos,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-APR-2022) Microbiology, Instituto Tecnologico de
            Sonora, Calle 5 de Febrero 818, Urb. No. 1, Obregon, Sonora 85000,
            Mexico
REFERENCE   4  (bases 1 to 4125766)
  AUTHORS   de Los Santos Villalobos,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2018) Departamento de Ciencias del Agua y Medio
            Ambiente, Instituto Tecnologico de Sonora, 5 de Febrero 818 Sur,
            Obregon, Sonora 85000, Mexico
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 02-DEC-2021
            Assembly Method                   :: Unicycler v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology :: Illumina MiSeq; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004124315.2-RS_2024_05_18
            Annotation Date                   :: 05/18/2024 04:23:33
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,221
            CDSs (total)                      :: 4,100
            Genes (coding)                    :: 3,993
            CDSs (with protein)               :: 3,993
            Genes (RNA)                       :: 121
            rRNAs                             :: 10, 10, 10 (5S, 16S, 23S)
            complete rRNAs                    :: 10, 10, 10 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 107
            CDSs (without protein)            :: 107
            Pseudo Genes (ambiguous residues) :: 0 of 107
            Pseudo Genes (frameshifted)       :: 76 of 107
            Pseudo Genes (incomplete)         :: 46 of 107
            Pseudo Genes (internal stop)      :: 32 of 107
            Pseudo Genes (multiple problems)  :: 41 of 107
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:49:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 222676
            Orig. end                         :: 243085
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP096889.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20409
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     cand_cluster    1..20409
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20409
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:15409](+)"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..15409
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     gene            complement(168..998)
                     /locus_tag="EFK13_RS01270"
                     /old_locus_tag="EFK13_01270"
     CDS             complement(168..998)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010331462.1"
                     /locus_tag="EFK13_RS01270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EFK13_01270"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_129506889.1"
                     /transl_table=11
                     /translation="MLSIGEFSKICKVSTKTLRYYDEIGLIHPEDINPENGYRYYSIRQ
                     LKEMLLINRLKSYRFSLEEIKTILDTDEDQAEEKLIFGLERKRQEVQAKIHAYEYTLTQ
                     MNQDMQRAEKGKSMMSWFDDIEVMLAETQPMNILYIRQMLSSDDYALGYEKYFSRLYER
                     IAVDKLTLLGTPMTIYHSPEYNPAGNDTEFAIPIEETVTGTRDLRAGLCAKSVLKGPYA
                     ELTAVYAKLREWVEDKGYELAQSPYEVYVTDHQQADVPENIVTEVYFPIKKKER"
     gene            1134..2111
                     /locus_tag="EFK13_RS01275"
                     /old_locus_tag="EFK13_01275"
     CDS             1134..2111
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388081.2"
                     /locus_tag="EFK13_RS01275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EFK13_01275"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_129506888.1"
                     /sec_met_domain="PF00561 (E-value: 1.5e-06, bitscore: 26.0,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTLWKVLKIVFGGLAALVLLVSVSVFIYHHYQLNKEAALLKGKG
                     TVVDVDGKKMNVYEEGSGKDTFVFMSGSGIAAPAYEMKGLYSKFSKENKIAVVDRAGYG
                     YSDVSNDDRDIDTVLEQTRKALMKSGNKPPYILMPHSISGIEAIYWAQKYPKEIKAIIA
                     MDIGLPQQYVTYKLSGIDRLKVRGFHLLTSIGFHRFMSSAVYNPEVIRQSFLTDKEKEV
                     YKAINFKQFFNADMEHELLQSYQNGRKSVNLPAPKETPVLILDAVSDQNRNSKYAIQNR
                     KDYEAFAAQFNTADIKELRGTHSIYLYQPDQIYKLSMEFMRKVR"
     gene            2113..2784
                     /gene="ybdJ"
                     /locus_tag="EFK13_RS01280"
                     /old_locus_tag="EFK13_01280"
     CDS             2113..2784
                     /codon_start=1
                     /gene="ybdJ"
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388082.1"
                     /locus_tag="EFK13_RS01280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EFK13_01280"
                     /product="two-component system response regulator YbdJ"
                     /protein_id="WP_129506887.1"
                     /transl_table=11
                     /translation="MKGYQILIVEDDVMIGDLLQKILQREGYHVIWKTDGADVLSVIQK
                     VDLVIMDVMLPGEDGYQISAKIKKLGLRIPVIFLSARNDMDSKLQGLQIGEDYMVKPFD
                     PRELLLRMQNMLEHHYGTFTQIKHLYIDAETKKVFNESLHDEVLFTAIERKIFFYLYEN
                     RDSTLTKDHFFEYLWQLEDRNPNIVNVHIKKIRAKINDQAGEIIENIYGEGYRLNTVVK
                     K"
     gene            2781..3767
                     /locus_tag="EFK13_RS01285"
                     /old_locus_tag="EFK13_01285"
     CDS             2781..3767
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017150458.1"
                     /locus_tag="EFK13_RS01285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EFK13_01285"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_129506886.1"
                     /transl_table=11
                     /translation="MKLKTKYMLLLFTAVISVPVLLLAVSILMSVIYDSMFKSMNHGMP
                     FHRSFAYPAMLVVFLLSLLLLAFLFSKSIHSLLHKINLLHHTIRHLASDQKVPDKIEVK
                     RADEIGELIKSVNLLIERTTYRELELKQQEEIKKELLQKLRHDINTPLTALRLQLFYLE
                     GQCHDQAVFESLYQQIEYISKLTNEFNLYSAETLESSYIVNEEVRLNELLETAVKKWDY
                     LYSMNGIELHFKPADQDVIWMSNVLWMQRLFDNIFQNTLKHSKAEKMEVTIEDGTVSIR
                     DDGIGFDQNENSEGLGLKIIEDICRLLHINYHLKADKTGTCFNFKKR"
     gene            complement(3958..4845)
                     /locus_tag="EFK13_RS01290"
                     /old_locus_tag="EFK13_01290"
     CDS             complement(3958..4845)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003223677.1"
                     /locus_tag="EFK13_RS01290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EFK13_01290"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_129506885.1"
                     /transl_table=11
                     /translation="MNLHALRLFYTVAEEGNVTCAAKKLNISQPAVTSQIKKLEKEIGL
                     TLLSPNGRGILLTQTGLQLAKQAKRLFSLQNEIESFLEHLKEGSVGKLHIVATSLPANF
                     LLPKWISRFKGDYPDVDVEMTTVNSTEAINQLVNYKADLGIIGGNRTFNKHISSTLLLE
                     DEMLFISNNKHKYAEQTIKLEDIVNEPFVFREEGSFSRELLFSLCNLFNVNKPCTGLQM
                     NGLNETINTVIEGYGVTFVSSLEVNSYISRGDVKRINVEHVDVTNPISLCWRNDDVIST
                     SAFNFIELIRKEKM"
     gene            5001..6302
                     /gene="thrC"
                     /locus_tag="EFK13_RS01295"
                     /old_locus_tag="EFK13_01295"
     CDS             5001..6302
                     /EC_number="4.2.3.1"
                     /GO_function="GO:0004795 - threonine synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thrC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PALP"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003223678.1"
                     /locus_tag="EFK13_RS01295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EFK13_01295"
                     /product="threonine synthase"
                     /protein_id="WP_129506884.1"
                     /sec_met_domain="PALP (E-value: 3.8e-53, bitscore: 178.7,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKFVCIDCGREMSSDDFNYQCSCSGLVDIVHDFSHYDTDFLKHVF
                     HERLSERMSVFASGVWRYKELIYPDLPVESVVTKYEGNTGLYSSEMLSNYTGLRKVYLK
                     AQSENPSGSFKDNGMTVAVSHGKHLGYEKYACTSTGNTSSSLGMYASIANAASYVFVPD
                     KEISINKVLQTAAYGGNVFSIPGTYDDGIRFLEKYNGDFGFYICNSINPFRIEGQKSII
                     FEIAQYLDWELPDWIIVPGGALSNATALGKGLRDLYALNFIDKMPRVAIIQAEGASPFH
                     QMVSENKGTLEPEPFPYTRASALNIGNPPSWKKARKVLEDTNGITVSVTDEDILDAKAI
                     IDRTGVGCEPASASTVAGLRQLRSQQVIDKDESVLCILTGNILKDTGALHDYHFGKDLN
                     GKFKNNIKSTELSLAEIKSAMETISDLNGLLKSH"
     gene            6350..7561
                     /locus_tag="EFK13_RS01300"
                     /old_locus_tag="EFK13_01300"
     CDS             6350..7561
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013307900.1"
                     /locus_tag="EFK13_RS01300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EFK13_01300"
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="WP_240034930.1"
                     /sec_met_domain="RimK (E-value: 4.3e-05, bitscore: 21.1,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp_3 (E-value: 1.2e-05, bitscore:
                     23.3, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 1.3e-06, bitscore:
                     26.1, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTSYSKSPYDLWLKDLEEPVVMLTSTERMNECQNYDQIESFDE
                     YPVNGCIEIRALKLHETYRFNTIIAMSEYDLLRAGKLRTHLGLRGQSYESALLFRDKVL
                     MKQCLEEAGIPVPHYRKIESPVDLYLFVQQFGFPVVVKPIDGSGSVDTKVLKNESDMME
                     YLSKGLDRNVEVETFVDGDMYHIDGLKIDGHIILNWPSRYINGCLAFQEEQFLASYQLG
                     ADNPLTSRLIDIVEKALKVLSSPETTTFHAEVFHTPDDKLVFCEIASRTGGGLIREAIQ
                     QSFGFDLNEICVKKQCGLPHEIPGYPQLKMGPKPLSGWILIPPKYGRLVKIPSIPFENW
                     VTKQKVSAKEGEVFQGASSSVDVVSSYLIKGDTEDVLINRIHQVATWCTENMVWEDQST
                     WSLK"
     gene            7507..8769
                     /locus_tag="EFK13_RS01305"
                     /old_locus_tag="EFK13_01305"
     CDS             7507..8769
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003223682.1"
                     /locus_tag="EFK13_RS01305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EFK13_01305"
                     /product="MFS transporter"
                     /protein_id="WP_248894263.1"
                     /transl_table=11
                     /translation="MVYREYGLGRSINVVSQIKEFFGLHPVIKFLLLGTLVTKAAKSMT
                     TPFLAIYLHQETGEGFGVIGLVIGLGYFATTIGGIIGGTLSDRIGRKSVMLCSIFIWSV
                     VFFLFGIVHTILWFSLLNILSGLCHSFFEPVSKALMVELAGSKKRLSIFSLRYLAINVG
                     GALGPLLGTYLGLVSSGTPFIITGSVYLCYALLLFFMMNKMVLQNKSNSKKEFHLPFIF
                     KTLKKDVALRFYIAGGIFLLFSYSQMESTLLQYLNLDFVNGVKIFSTLITINAVTVIIL
                     QLPLTGLFERYNTMITICTGSVCCIIGNIGFALSNGWLTFCISMFILTVGEILCFPSMN
                     VLMDELAPDNMRGTYYGAQNFYNVGEFIGPWLGGIVLSLFGGRTIFLVAALSICFALAA
                     YRVGNRKHRFVQPYETEVMNK"
     gene            8805..9308
                     /locus_tag="EFK13_RS01310"
                     /old_locus_tag="EFK13_01310"
     CDS             8805..9308
                     /GO_function="GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003223684.1"
                     /locus_tag="EFK13_RS01310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EFK13_01310"
                     /product="thiamine pyrophosphate-binding protein"
                     /protein_id="WP_129506881.1"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.7e-07, bitscore:
                     28.9, seeds: 75, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSTAERMLNTLTENKYTHFTGVPCSLLKGFFRLLESKEATEKQN
                     ITFVPSIREDSALGVASGMYLGGKKCVMLMQNSGLGYCLNVLTSFNFIYDIPILLLISW
                     RGAYGNDAVEHDIIGEKLTDLLHSVDIPYKELDYENSEGTILDALFLIEKTNRPVAILI
                     KDEI"
     gene            9322..9882
                     /locus_tag="EFK13_RS01315"
                     /old_locus_tag="EFK13_01315"
     CDS             9322..9882
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003223687.1"
                     /locus_tag="EFK13_RS01315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EFK13_01315"
                     /product="thiamine pyrophosphate-dependent enzyme"
                     /protein_id="WP_129506880.1"
                     /sec_met_domain="TPP_enzyme_C (E-value: 8.3e-14, bitscore:
                     49.6, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKHDAIQLVLGQFPSAYLVSTCGHISRDLYNIHDRARNFYMVGS
                     MGMAAPVGLGLSAVYPDVPLVVLDGDGSFLMNMGIITMIGHQKPKNLIHVVLDNGMHES
                     TGGQKTVPLVNVTDIALQAGYEYAIEINSVQETFDLPKKGPGLIHIKVEPRSEKIGNRV
                     HWTPQEIVQRFTNELKSENEVSV"
     gene            9879..10892
                     /locus_tag="EFK13_RS01320"
                     /old_locus_tag="EFK13_01320"
     CDS             9879..10892
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003223689.1"
                     /locus_tag="EFK13_RS01320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EFK13_01320"
                     /product="aldolase"
                     /protein_id="WP_129506879.1"
                     /sec_met_domain="HMGL-like (E-value: 8.9e-36, bitscore:
                     121.7, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKMQLIDCTLRDGGNFNNWFFSDEDINQIILHLDKANVNIIEIGY
                     IGGSGSNKEKSVGSLANCTPELLDQLPKTIHSRLAAMVVPSVCELHLLDNLKPQLIPWI
                     RVASYPHNAEDALPYIEYLKNRGFHVSFNVMAASYIEEKDMAELARKSYILGADVFYMA
                     DSFGNLTPDGVRKRVAAACDQSNCPVGFHGHNNLGLAFTNALEAMDAGATFIDTSLCGM
                     ARGAGNLPTEQFVSALHHWDKFDNIPYNLHPILTAAEYVLSTILSSPMKISTPEIISGL
                     SNIHYYFYDLVISKCQEVNLDPLQVSKLLGQSLPKRVDMSYIESVIDQKFRQESVK"
     gene            10889..11779
                     /gene="aepX"
                     /locus_tag="EFK13_RS01325"
                     /old_locus_tag="EFK13_01325"
     CDS             10889..11779
                     /EC_number="5.4.2.9"
                     /GO_function="GO:0050188 - phosphoenolpyruvate mutase
                     activity [Evidence IEA]"
                     /GO_process="GO:0019634 - organic phosphonate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="aepX"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) phosphonates-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231: carboxyvinyl-carboxyphosphonate"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003223692.1"
                     /locus_tag="EFK13_RS01325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EFK13_01325"
                     /product="phosphoenolpyruvate mutase"
                     /protein_id="WP_129506878.1"
                     /sec_met_domain="phosphonates (E-value: 5.1e-132, bitscore:
                     437.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates-like (E-value: 1.2e-141,
                     bitscore: 468.5, seeds: 13, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 1.6e-69, bitscore:
                     232.0, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAKKLRELLYSNQVVRVMGAHNGLSAKLAEQAGFHAIWASGLEI
                     SASYAVPDANILTMTENLQAAIVMNESTSIPIICDCDSGYGSVNNVIRLVKEYERNGIA
                     GICIEDKQFPKLNSFVKGSQKLASIDEFSNKIRAAKDVQKNPDFVVIARIEALIAGQGM
                     EEALNRAYAYEAAGADAILIHSKESQPDEIKNFVKQFTGAIPIVIVPTTYPHITVKEME
                     LMGINMVIYANHGLRSSIKAMQETFSQILLDGNTVGIEDNIVSMNTVFELQGMYEMRKQ
                     EDMYNSAASVISTIK"
     gene            11801..12889
                     /locus_tag="EFK13_RS01330"
                     /old_locus_tag="EFK13_01330"
     CDS             11801..12889
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003223694.1"
                     /locus_tag="EFK13_RS01330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EFK13_01330"
                     /product="hypothetical protein"
                     /protein_id="WP_129506877.1"
                     /transl_table=11
                     /translation="MISNQYDIVSLAYLHSKINFFIEPSLSLDHVFDFFSTHFFINRGR
                     HEEDRLADVYITRNKEEFQTVDFNSGDDIYIRKSASEYFTIPCKRVTVNGIEYVKCTKT
                     DTIFSFDRENKKIIISTQLHNAEQDKLVLIEFVRDLVLKNEENHGVAVLHATSALKDAK
                     ATLIIGSKGKGKSTLLLELVSKQGYKLISGDKTFLWIEDGKLRASGWPDYPHLGLGTLS
                     KYPEFVEHFGLSNKIESIKENLWSTEHKMAIDPVFFKKVIPFAEPGQSFMVECMIYPDL
                     FPSTECRINQVSNHGELIVPHIERIFTKENTMWNHFICPVHQNELERKINQCIELAGKF
                     SAFEVSGSGILEGSVFSERYAL"
     gene            12927..13325
                     /locus_tag="EFK13_RS01335"
                     /old_locus_tag="EFK13_01335"
     CDS             12927..13325
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003223695.1"
                     /locus_tag="EFK13_RS01335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EFK13_01335"
                     /product="YjbQ family protein"
                     /protein_id="WP_129506876.1"
                     /transl_table=11
                     /translation="MVEITIQSKGFNHSYDITEQVTDALSQLEPSSGLVKVCVTGSTVG
                     LTVMRYEPGTVQDLLQCLESIASKNKQYEHFNTTGDSNGFSHVWSTIIGTSVMVPYKNH
                     KLACSDSHRVVLFDFDLREAERKIYVDH"
     gene            13342..14496
                     /locus_tag="EFK13_RS01340"
                     /old_locus_tag="EFK13_01340"
     CDS             13342..14496
                     /NRPS_PKS="Domain: Aminotran_5 (8-324). E-value: 1.1e-42.
                     Score: 138.3. Matches aSDomain:
                     nrpspksdomains_EFK13_RS01340_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139: aminotransferase class V"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003223698.1"
                     /locus_tag="EFK13_RS01340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EFK13_01340"
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="WP_240034929.1"
                     /sec_met_domain="Aminotran_5 (E-value: 6.9e-30, bitscore:
                     102.1, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKLRMATPGPTQVPQEILLAGAQEMIHHRSRQMEDIINEINHEL
                     PDLFLTKQDIYILLSSGTGAMEAAVSNSFSRGDKVLVVTNGYFGERFTDICTIFGLEVI
                     TVSSPWGTSVNIEEVERAYKQHPDIKGVLVVYSETSTGAVNDVEAIGALFRDTEVLVIV
                     DAISGLISHELSMDDWGLDIVLAASHKGFMMPPGLAFVAISPKAWEVINKIQPSTYYFS
                     FKRFKKFYPMAPSSPGVSLLLALKKSLDLLKEEGLSNATRRHARIAMATQRGLEALGFH
                     LFVQSPHVRSHTVTAALAPSGIDAALLLKILNKEYGLTITGGQGEFKGKMIRIGHIGAV
                     DEIDLFGIFGILEQVLAEMGYQVHSGASTTALSDALGGGVIYHA"
     aSDomain        13366..14313
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EFK13_RS01340_Aminotran_5.1"
                     /evalue="1.10E-42"
                     /label="EFK13_RS01340_Aminotran_5.1"
                     /locus_tag="EFK13_RS01340"
                     /protein_end="324"
                     /protein_start="8"
                     /score="138.3"
                     /tool="antismash"
                     /translation="PGPTQVPQEILLAGAQEMIHHRSRQMEDIINEINHELPDLFLTKQ
                     DIYILLSSGTGAMEAAVSNSFSRGDKVLVVTNGYFGERFTDICTIFGLEVITVSSPWGT
                     SVNIEEVERAYKQHPDIKGVLVVYSETSTGAVNDVEAIGALFRDTEVLVIVDAISGLIS
                     HELSMDDWGLDIVLAASHKGFMMPPGLAFVAISPKAWEVINKIQPSTYYFSFKRFKKFY
                     PMAPSSPGVSLLLALKKSLDLLKEEGLSNATRRHARIAMATQRGLEALGFHLFVQSPHV
                     RSHTVTAALAPSGIDAALLLKILNKEYGLTITGGQ"
     gene            14489..14746
                     /locus_tag="EFK13_RS01345"
                     /old_locus_tag="EFK13_01345"
     CDS             14489..14746
                     /GO_function="GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GST_N_3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003223700.1"
                     /locus_tag="EFK13_RS01345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EFK13_01345"
                     /product="glutaredoxin domain-containing protein"
                     /protein_id="WP_129506875.1"
                     /sec_met_domain="GST_N_3 (E-value: 7.2e-08, bitscore: 30.7,
                     seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKLYQRETCPYCKPVREKLTELNITYINVNLPKDRALRTELIEK
                     TGVPYIPALIDEEDNVIISGRLEYNQHVLDYIEKKFGQNR"
     gene            14762..15409
                     /locus_tag="EFK13_RS01350"
                     /old_locus_tag="EFK13_01350"
     CDS             14762..15409
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Metallophos_2"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003223702.1"
                     /locus_tag="EFK13_RS01350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EFK13_01350"
                     /product="metallophosphoesterase family protein"
                     /protein_id="WP_129506874.1"
                     /sec_met_domain="Metallophos_2 (E-value: 1.9e-11, bitscore:
                     42.2, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRYAFITDIHGKRDNLEKVLEHIQTFSSIHEIICLGDVFEVKVPK
                     KDLKDFQFQCMEQVLDLDWKLMNLLKDIRVIKGNQEERILSLIPEKELPIDFYNFLIHM
                     PLEIHLTPMVRLTHGHNFDWTEEEEDYWRPGNVHWNSPWIFYGHNHQNVLFEVKSKENN
                     PYYERKSIINGKPITLDSESRYLINIGDMKYDHPSWMLLDTLENQITYNILY"
     gene            15426..16667
                     /locus_tag="EFK13_RS01355"
                     /old_locus_tag="EFK13_01355"
     CDS             15426..16667
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003223704.1"
                     /locus_tag="EFK13_RS01355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EFK13_01355"
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="WP_129506873.1"
                     /transl_table=11
                     /translation="MLRILLINSDKPEPIHFFRKDKETNDTVNISVITRSCYASLYSHW
                     ADHVYIVDDVTDLTVMKSLMLEILKVGPIDHIVTTTEKSILTGGFLRSYFGIAGPGFET
                     ALYMTNKLAMKTKLKMEGIPVADFLCLSQVKDIPAAGEKLGWPIIVKPALGSGALNTFM
                     IHSLDHFEDLYSASGGLGELKKNNSLMIAEKCIEMEEFHCDTLYADGEILFVSISKYTV
                     PLLKGMAKIQGSFILSQNDPVYLEILELQRSVARAFRFTDGPGHLEIYRTRSGELIVGE
                     IAMRIGGGGISRMIQKKFNISLWESSLNVSINRDLNLMVNPIEGTVGYFSLPCRNGTIK
                     DFTPTEDWEKLAGILEVELLYQEGDVVDEKQSSSFDLARLYFCLENENEVQNLLALVKQ
                     TYYLHLTEDQMMNQ"
     gene            16765..17027
                     /locus_tag="EFK13_RS01360"
                     /old_locus_tag="EFK13_01360"
                     /pseudo=""
     CDS             16765..17027
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_003097672.1"
                     /locus_tag="EFK13_RS01360"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="EFK13_01360"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MISICLKKSSKRSSTSQAALVTDIADTDITAAAGADITAATAAAQ
                     AKEDTTTVMAGVIVTNAGATAAVNPKKFLFRFWDKGFFM"
     gene            complement(17012..17782)
                     /locus_tag="EFK13_RS01365"
                     /old_locus_tag="EFK13_01365"
     CDS             complement(17012..17782)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388085.1"
                     /locus_tag="EFK13_RS01365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EFK13_01365"
                     /product="protein kinase"
                     /protein_id="WP_129506871.1"
                     /sec_met_domain="Pkinase (E-value: 3.8e-32, bitscore:
                     109.6, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALKQLKKLLFDRPLRDGVILNNQYKIEECLGMGGYGLVYSCTDV
                     HTQTAYVLKQLRPTKAKKEKERVRFQQEMKLLKSIHHPQIPAFIENFIIDGQAYYVMQL
                     IEGENIEELLFFRKQPFTELMALQLLSQLLGIVEYLHDRFIFHSDIRTPNIIINDGRLC
                     LIDFGLAKQLTPEETEEIKVRKQDDFFDLGETLLFLLYSQYKGKKKKNGTWLEELTLTN
                     EVTLLLKKLLGIDEEYQHTASIREDVNRAIQSVT"
     gene            complement(17868..18725)
                     /locus_tag="EFK13_RS01370"
                     /old_locus_tag="EFK13_01370"
     CDS             complement(17868..18725)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388086.1"
                     /locus_tag="EFK13_RS01370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EFK13_01370"
                     /product="hypothetical protein"
                     /protein_id="WP_129506870.1"
                     /transl_table=11
                     /translation="MMKKWLIPFAIMLSVLFTFTYSASAAGVTAITGNNSFDTAMPIGY
                     WKYKNIDTTILEAGKDEAYFTFTANKGEKVYVKSTYQSAYTGMKIEIYDKNRAPVSQGT
                     EVISPTTFSSFIYANADAQNTTDTFYVKVSRGSYTGNMYFTISIENRIKSGSGTFQFNG
                     VAENKGNTALSPSGSDSSVIKADLTNQSGIPHDAIVTRVQTTATQTPSQGNTRHFIMTS
                     ENNEWRRALVNSSTSGSYDISLSDQLSVAKVWSFKYNTLATARSTMSNVKAKIDYEYDV
                     TKQF"
     gene            18858..20042
                     /locus_tag="EFK13_RS01375"
                     /old_locus_tag="EFK13_01375"
     CDS             18858..20042
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388087.1"
                     /locus_tag="EFK13_RS01375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EFK13_01375"
                     /product="DUF4885 domain-containing protein"
                     /protein_id="WP_129506869.1"
                     /transl_table=11
                     /translation="MRLNRQFIRTQMLAENILKKDAAVKREKTPGNTAAALDKAYGRLE
                     SRSANEGINQFNYSKTSVAGNSGTFSKVYQAANVRTVTDTGAETVIESTNPYESESDIR
                     IKILDEKYSRINAINKTKPDPLGYIKDKYQNSKSPYFRSDLSAAERQAAYDNETEWLFK
                     GKAQNYNLQDAAFRNVTFNGEVEAENAKVYQRSQVNQQLQVLLNRNHIHIPEGTALTFT
                     ITPIDYKVRVSGTDDEDLIKQIEQVLQSGDNSKELFLHIMKSQSSDSTQFSEEAYKKYQ
                     AAREMYEVTGYHLKDLEVIDGRYVTPDGRDLLDVYKEELEKDPVQKATALYAVSHYRSE
                     LSKIAEAGYDAIPDFILSIDYSNGSLRDVGQSKSYGAGDTEWLDTLKRQTGVNY"
ORIGIN
        1 gctatgataa tagcgctcaa aagcgacgta tccatttttt acaaccacca taccgtttat
       61 attgctgtat tcggacttga ttttaaggtc aagctcagac agtttttcgg cgttcatgcc
      121 tagggctgcc gggcctgcag ttggccagtc gtttctttgc atgaccgtta cctctctttt
      181 ttctttattg gaaaatacac ttcagtcaca atattctctg ggacatcagc ttgctggtga
      241 tcggttacat acacttcata gggtgattgc gccaattcat agcccttatc ttcgacccat
      301 tcccttagct tagcgtatac cgctgtcaat tctgcatagg ggccctttaa tacagacttt
      361 gcgcaaaggc ctgcgcgcaa atctcttgtt ccagtaacag tctcctctat tggaatcgca
      421 aactctgtat cattgccggc agggttgtat tcagggctgt gataaattgt catgggcgta
      481 ccgagcaagg taagtttatc aacggcaatt ctttcatata gtctgctaaa atacttctca
      541 tatcctaagg cgtagtcatc actgctcagc atttggcgta tataaagaat gttcattggc
      601 tgggtttcgg caagcattac ttctatatcg tcaaaccatg acatcattga tttgcccttc
      661 tctgcacgtt gcatatcttg gttcatttgt gtaagagtat attcataagc atggatcttt
      721 gcctgtactt cttgtctttt tcgctcaagg ccgaaaatta gcttttcttc tgcctgatcc
      781 tcatctgtat cgagaatggt tttgatttct tccagtgaaa agcgatacga ctttaaacgg
      841 ttaatcaaga gcatttcttt cagctgcctg atagaataat atcgatatcc attttcaggg
      901 ttaatgtcct cagggtggat taatccaatt tcatcatagt atcgcagtgt ttttgttgat
      961 actttgcata tctttgaaaa ttcaccgatc gatagcaagc gatcacctcc atgctccaaa
     1021 tgtacacctt tccgtaaggg caaagtcaaa tgtcaaaata aaatctttcc aaaattaatc
     1081 agaaatttat tttcatatcg tatcctttcc ttatcacgtg aaaggagcaa catatgaaaa
     1141 cattatggaa agtcctaaag atcgtttttg gcggcctggc tgctttggtt ttgctagttt
     1201 ccgtctccgt ttttatttat caccattacc agctaaataa ggaggcggca ctgttaaaag
     1261 gcaaaggcac agtagtcgat gttgatggga aaaagatgaa tgtgtacgaa gagggaagcg
     1321 ggaaggacac gtttgtgttt atgtccggct cggggattgc tgcgcctgct tatgagatga
     1381 aaggtttgta cagcaaattt tcaaaagaaa ataagattgc tgttgtagat cgggcaggtt
     1441 atggatacag tgatgtgtct aacgatgaca gagatattga tacggtactg gaacagacaa
     1501 ggaaagcgct tatgaaaagc gggaataagc ctccttatat tttaatgcct cattccatat
     1561 caggcatcga ggcgatttat tgggcgcaga aatatcctaa ggaaatcaag gccattattg
     1621 cgatggatat tggcttgcct cagcagtatg tcacgtataa gttgagcggg attgacagac
     1681 tgaaagtgag aggattccat ctgttaacgt cgattggctt tcatcggttt atgtcttccg
     1741 ctgtatataa tcccgaggtg attcgccagt cgtttttaac cgataaagaa aaagaagtct
     1801 ataaagccat taactttaag caatttttta atgctgatat ggagcatgag cttttacagt
     1861 cttaccaaaa cggcaggaaa tctgtaaatc tgccggcgcc aaaagaaact cccgtcttga
     1921 ttttagatgc ggtctctgac caaaatagaa actcaaaata tgccatacaa aacagaaaag
     1981 attatgaagc gtttgcggct caattcaata cagccgatat aaaggaactg aggggtacac
     2041 acagtattta tttatatcag cctgatcaaa tatataaact ttccatggag tttatgagaa
     2101 aggttcgcta ggatgaaggg ttatcagatt ttaatcgtgg aagacgatgt aatgattggc
     2161 gatctgctgc aaaagatttt gcagcgtgag ggctatcatg tgatatggaa gaccgatgga
     2221 gcggatgtgc tttcggtcat acagaaggtg gatttggtca ttatggatgt gatgctgccg
     2281 ggtgaagacg gctatcaaat atctgcaaaa atcaaaaagc tggggctgcg cattccggtc
     2341 atttttctat cggctcgcaa tgacatggac agcaagctcc aaggtttgca gatcggcgag
     2401 gattatatgg tgaagccctt tgatccgaga gaactgctgt taagaatgca gaatatgctt
     2461 gagcatcatt atggaacctt tacgcaaatc aagcacttgt atattgatgc ggaaaccaaa
     2521 aaagtgttca atgaaagcct gcatgatgag gtgttgttta ctgccattga gcggaaaatt
     2581 ttcttttatt tatatgaaaa tagggacagc accctgacaa aggatcattt ctttgaatat
     2641 ctgtggcagc tcgaagacag aaacccgaat attgtcaatg tacacattaa aaaaatcaga
     2701 gccaaaatca atgatcaagc gggtgagatt attgaaaata tatatggaga agggtatcgg
     2761 ctgaataccg ttgtgaagaa atgaagttaa agacaaaata tatgttgtta ttatttacgg
     2821 ctgtcattag tgtgccggtg ctattgctgg cagttagtat tttgatgtct gtcatttatg
     2881 acagcatgtt taaatcaatg aatcacggca tgccttttca taggtctttt gcgtatccgg
     2941 caatgctcgt tgtatttttg ttatcactct tattgttggc ttttttattt tcgaagtcga
     3001 ttcattctct gctgcataaa atcaatctat tacatcatac cattcggcat ctggcgagtg
     3061 atcaaaaggt gccggataaa atagaagtga aacgcgctga tgaaatcgga gagctgatca
     3121 agtcggtcaa tttgttgatt gaacggacga catatcgtga actggaattg aaacagcagg
     3181 aggaaatcaa aaaggagctt ttgcaaaaac tgcgtcatga cattaacaca cctttaacag
     3241 ctctcaggct gcagttgttt tatttggaag gccaatgtca tgatcaggcc gtattcgaat
     3301 cgttgtatca gcaaattgaa tatatctcga aattaaccaa tgaattcaat ctatattccg
     3361 ccgagacgct agaaagttct tatatcgtaa atgaagaagt gcgtcttaac gagctgttag
     3421 aaacagcggt gaaaaagtgg gattatttat atagtatgaa tgggattgaa ttgcacttta
     3481 agccggcaga tcaagatgtg atatggatga gcaacgtgtt atggatgcaa aggctgtttg
     3541 ataatatttt tcaaaatacg ttaaagcatt caaaagctga aaagatggaa gtcacgatcg
     3601 aagatggcac tgtttctatt cgtgatgatg gtattggatt tgatcagaat gagaatagtg
     3661 aggggcttgg gttaaagatt attgaggata tatgcaggct gcttcatatt aattatcatt
     3721 taaaagcaga taaaacagga acttgtttca attttaaaaa aagataaatt gtaaacccct
     3781 tagtaagtat atgcaagggg ttttttaaac tgttcaatat ataaaaaatt aatagaatgc
     3841 aagtggtatg ttaaggatga agagttaaaa aaggtgttta aatcactttt ggaaactttt
     3901 gcaagagttc agttcatgaa gaataatatg cgcttatata ataaagtgtt aagattatta
     3961 cattttttct tttcttatca gttcaataaa attaaatgcc gatgtcgaga tgacatcatc
     4021 atttctccag cataacgaaa taggattagt aacatccaca tgttccacat taattctttt
     4081 aacgtctcct cttgatatat agctattgac ttcaagcgaa gaaacaaatg ttacaccata
     4141 cccttctatg acagtgttaa tggtttcatt taacccgttc atttgtaatc ctgtacatgg
     4201 cttatttaca ttgaaaagat tgcataaaga gaacaataac tctctagaaa aactcccttc
     4261 ctcacgaaaa acaaacggtt cgtttacaat gtcctctaat tttatagttt gttctgcata
     4321 tttatgttta ttattggaga taaataacat ttcatcctcc aataataatg tactgctaat
     4381 gtgtttatta aacgtcctgt ttcccccaat aataccgagg tcagccttat aatttactaa
     4441 ttgatttatg gcttctgttg aattgactgt ggtcatttcc acatcaacat cagggtaatc
     4501 tcctttaaaa cggctgatcc actttgggag caaaaaatta gctggtaaac tagttgccac
     4561 gatgtgcagc tttcctacag agccttcttt tagatgttcc aagaaggatt caatctcatt
     4621 ttgaagcgag aataatctct ttgcttgttt agcaagctgg agtcctgttt gtgttaaaag
     4681 aattcctctt ccattagggc taagcaaagt cagtccaatt tctttctcaa gttttttaat
     4741 ctgagatgtc acggcaggct gacttatatt tagttttttg gcggcacatg tgacatttcc
     4801 ttcctcagct acggtgtaga acagtctcaa tgcatgaaga ttcatcgttc atctctccat
     4861 tcataaaaaa taattatgat tacaaaaaat atatatatta gaattttcca taaatacata
     4921 ttattataaa ttcataatat aacaacttca ataaattact attttaggtg gtgagaggac
     4981 agcttgatgt ctagcgaaat atgaaatttg tatgtatcga ctgtggccgg gaaatgtctt
     5041 ctgatgattt taattatcaa tgttcttgta gtggacttgt agatattgtt catgattttt
     5101 ctcattacga taccgacttt ttaaagcatg tatttcatga acgcctatct gaacgtatgt
     5161 ctgtttttgc aagcggagta tggagatata aagaacttat atatccagat ttgccagttg
     5221 aaagtgtcgt tacaaaatat gaagggaaca cagggttata cagctctgag atgctatcaa
     5281 attataccgg gttgagaaag gtatatctaa aggcgcaaag tgaaaacccc agcggttctt
     5341 ttaaggataa cggcatgact gttgctgttt cacatggcaa acatttaggt tatgaaaaat
     5401 acgcttgtac ttctaccgga aatacttctt catcattggg aatgtatgcc tctattgcaa
     5461 atgctgcgtc ctacgttttt gtaccggata aagaaatttc aattaataag gtattgcaaa
     5521 cagcagctta cggtggaaat gtatttagta ttccgggtac ttatgatgac ggtatcaggt
     5581 ttttggaaaa gtataatggt gactttggtt tttatatatg caattctatt aatccattca
     5641 gaattgaagg gcaaaagagc attatttttg agatagctca atatctagac tgggaattgc
     5701 ctgattggat tattgttcct ggcggtgctc ttagtaatgc aacagcttta gggaaaggac
     5761 tccgcgattt atatgcttta aacttcattg acaagatgcc tcgggtcgct atcatacaag
     5821 cggaaggcgc tagcccattt catcagatgg ttagtgaaaa taaaggaacc cttgaaccgg
     5881 aaccatttcc gtacactaga gcttctgcat tgaatatagg aaatcctcct agctggaaaa
     5941 aagcaagaaa ggttttagaa gatacaaatg gaatcactgt atctgttact gatgaagaca
     6001 ttcttgatgc aaaagcaata atcgacagaa caggagtggg ctgtgagcct gcctctgcct
     6061 ctactgtagc aggactccgt caattgaggt cacagcaggt aatagacaaa gatgaatctg
     6121 ttttatgtat tttaacaggc aatatattaa aagatactgg agctcttcac gattatcact
     6181 ttggaaaaga cttaaacggc aagtttaaaa acaatattaa atctaccgag ctatctttgg
     6241 ctgagataaa atcagcgatg gagacgatta gtgatttgaa tggtttatta aagagtcatt
     6301 aattaaaaaa cagtacaaga gaggaggaaa agcaatcagt actttaatat tgaataaaac
     6361 gtcatattct aaatctccgt atgatttatg gctaaaggat ttagaagaac ctgttgtaat
     6421 gctaacttca actgaacgaa tgaacgaatg ccaaaactat gatcagatcg agtcatttga
     6481 tgagtatccg gttaatggat gtattgaaat aagagcgttg aaattacatg aaacatatag
     6541 atttaacaca ataattgcaa tgtctgagta tgacctttta agagcaggca aacttcgtac
     6601 tcatttagga ttgcgcgggc agtcttacga gagtgcatta ttgtttcggg acaaagtttt
     6661 aatgaaacaa tgtttagaag aagctgggat acctgttcct cattaccgga aaattgaatc
     6721 tcctgttgac ctgtaccttt ttgtacagca gtttggtttt ccggtagtcg ttaagccaat
     6781 agatgggtcg ggatctgtcg atacaaaggt gctgaaaaat gaatcagata tgatggaata
     6841 cctatctaag ggtcttgata gaaatgttga agtggaaacg tttgtagatg gtgatatgta
     6901 ccacattgat gggcttaaga tagacgggca tatcatatta aattggccct ctcggtatat
     6961 aaacggatgt ttggctttcc aggaggaaca atttttagcc agttatcagc ttggcgccga
     7021 caaccctttg acctcgagat taattgatat tgttgaaaaa gcactaaagg tgctgtcatc
     7081 cccagaaaca actacttttc acgcggaagt gtttcatact ccggatgata agctagtgtt
     7141 ttgtgaaata gctagccgaa ctggaggggg gttgatacgt gaggctattc agcaaagctt
     7201 tggttttgac ttgaatgaaa tttgtgtaaa aaaacagtgc ggcctacccc atgagattcc
     7261 aggttatcca cagcttaaaa tggggccaaa acccttaagc gggtggatat tgatccctcc
     7321 taaatacggg cggttggtca aaattccttc aattcctttt gagaattggg taacgaagca
     7381 aaaagtatct gctaaagaag gggaggtttt tcaaggtgct tcttctagtg tagatgttgt
     7441 atcgagttac ttaattaaag gggataccga agatgtactg attaatagaa ttcatcaagt
     7501 tgcgacatgg tgtaccgaga atatggtttg ggaagatcaa tcaacgtggt ctctcaaata
     7561 aaggagtttt tcggattaca cccggtcatt aagtttttgc ttttgggaac acttgtcaca
     7621 aaagcagcaa aatcaatgac aacaccgttt ttggctattt atcttcatca agaaacagga
     7681 gagggttttg gtgtaattgg tttggttatt ggcttggggt attttgcaac tacgattgga
     7741 ggaatcattg gaggaaccct ttccgacaga atcggcagaa aaagtgttat gctatgttcc
     7801 attttcattt ggagtgtagt tttctttctt tttggcatcg ttcatacaat attatggttc
     7861 agtttgttaa atattttaag tggtctgtgt cattcctttt tcgaaccagt ttcaaaggct
     7921 ttaatggttg aattagcagg cagcaagaag aggctcagta ttttttcttt gcggtatctg
     7981 gccattaatg ttggcggtgc tctaggtcct cttttaggaa catatctggg actggtgagc
     8041 agcggaaccc cttttattat tactggctct gtatatcttt gttatgctct attattattt
     8101 tttatgatga ataaaatggt tctgcaaaat aaaagcaatt caaaaaaaga atttcatttg
     8161 ccatttattt ttaagacact gaaaaaggat gttgctcttc gtttttatat agcaggcggt
     8221 atattcttat tatttagcta ttcacagatg gagagtacat tgcttcagta cctgaacctt
     8281 gatttcgtga atggcgtgaa gatattctca actttaataa ccataaatgc tgtaactgta
     8341 attatattgc agttgccatt aacaggcctt tttgagagat ataatacaat gataacgatt
     8401 tgtacgggaa gcgtgtgttg tatcatcggg aatattggtt ttgctttatc aaacggttgg
     8461 ctcacgttct gtatttctat gtttatttta actgtgggtg aaatcttatg tttcccatca
     8521 atgaatgtat taatggatga gttggcccct gataatatga ggggaactta ttatggagca
     8581 cagaattttt ataatgtagg ggagtttata ggcccatggc ttggagggat tgtccttagc
     8641 ctttttgggg gcagaaccat tttcttagtt gcggctttgt ctatctgttt tgctttagca
     8701 gcatatcgtg tcggcaatag aaagcataga tttgttcaac cttatgaaac tgaggttatg
     8761 aataaataat tattaggtta tttcttataa ggggagaact tgaattgaac tcaactgcag
     8821 aaagaatgct gaatacactt acagaaaaca agtatacaca ttttaccgga gtgccatgtt
     8881 cattgttaaa aggttttttt aggttactgg aatcaaaaga ggctacagaa aaacaaaata
     8941 ttacatttgt cccctccatt agagaagatt ctgctttagg tgttgcatcc ggtatgtatc
     9001 taggcgggaa aaaatgcgtg atgctgatgc aaaattcagg cttagggtac tgcttaaatg
     9061 ttcttacatc ctttaatttt atttatgata ttcctatttt attactaatc agctggagag
     9121 gggcatacgg taatgatgca gttgaacatg acataatcgg tgaaaaactc actgatttac
     9181 ttcattcagt ggatatccct tacaaagagc tcgattatga aaattctgaa gggaccatat
     9241 tagatgcgct ttttttaatc gagaagacaa accgccctgt tgcgatatta attaaagatg
     9301 aaatatagga ggtgtatttg tttgaataaa catgatgcaa ttcagcttgt tttaggccag
     9361 tttccatcag catatttggt tagtacatgc ggtcatataa gccgtgattt gtacaacata
     9421 catgacagag ccagaaattt ttatatggtt gggtccatgg gaatggctgc tcctgtcgga
     9481 ttaggtttgt ctgccgtata tcctgatgtt cctctggttg tgctagatgg agatggatcg
     9541 tttttaatga atatgggaat tatcacgatg atcggtcatc aaaaacctaa aaatcttata
     9601 catgttgttt tggataacgg tatgcatgaa agtacgggcg gacagaaaac agttcctcta
     9661 gtgaatgtaa cagatatagc tttacaagcg gggtatgagt atgccattga aatcaattca
     9721 gtacaggaaa cgtttgattt gcctaaaaag ggtccgggac ttatccacat taaagttgaa
     9781 ccaagaagtg aaaaaattgg caatagggtg cattggacac cgcaagaaat agtccagcgt
     9841 tttacaaatg aattaaagtc agaaaatgag gtttcagtat gaaaatgcaa ttaatagatt
     9901 gtacactccg ggacggcggt aatttcaata actggttttt ttctgatgaa gacatcaatc
     9961 aaatcatcct gcatctagat aaagccaatg tgaatataat agaaatcggt tatataggag
    10021 gatcaggcag caataaagaa aaatctgtcg ggagtttagc aaactgtaca cctgaacttt
    10081 tagaccagct gccgaagacg atccattcac gtttagcggc gatggttgtc ccatcagttt
    10141 gtgagcttca tctattggac aatttgaagc cgcagctgat tccatggatt cgtgttgctt
    10201 cgtatcctca taatgccgaa gatgctttac cgtatattga atacctaaaa aatcggggct
    10261 ttcacgttag ttttaatgta atggcagcca gttatattga agagaaagac atggctgagc
    10321 tagcgagaaa atcgtatatt ttaggtgcgg atgtgtttta tatggctgat tctttcggga
    10381 atttaacgcc tgatggtgtt agaaaaaggg tagcagctgc atgtgatcag tcgaattgcc
    10441 cagttggttt tcacggacat aacaaccttg gattagcctt tacaaatgcc cttgaagcaa
    10501 tggacgcggg agcaaccttc atagatactt cattatgtgg aatggctcga ggggcaggaa
    10561 accttccaac agaacaattt gtaagtgcat tacatcattg ggacaagttc gataacatcc
    10621 catacaacct acatccaatt ttaaccgcag ctgaatatgt actatctacc attctatctt
    10681 caccaatgaa aatttctact ccagagatta taagcggact cagcaacatc cattactatt
    10741 tctatgattt agtcatttca aaatgccaag aagtaaatct tgatccctta caagtatcaa
    10801 aattacttgg acaaagttta cctaaaagag ttgatatgtc ttacattgaa tcagttattg
    10861 atcaaaaatt tagacaggag agtgtaaaat gaaagctaaa aaattacgtg agttgctata
    10921 ttcaaatcag gtcgtgcgag taatgggggc tcataatggt ttaagcgcta aacttgctga
    10981 acaagccggt ttccatgcaa tatgggccag tggattggaa atttcggctt cttatgctgt
    11041 tcctgatgct aatattttga ctatgacaga aaatctgcaa gccgcaattg tgatgaatga
    11101 atctacatcc atcccaatca tttgtgattg cgattctggt tatggaagtg tgaacaatgt
    11161 gatacgtcta gtaaaagaat atgagagaaa cggaattgct ggtatttgta tagaagataa
    11221 gcaatttcct aaattaaaca gttttgtgaa aggatcgcaa aaattggcgt ctattgatga
    11281 attctcaaat aaaatcagag cggcaaaaga cgttcaaaaa aatcctgatt ttgttgttat
    11341 tgctagaatt gaagctttaa ttgcgggtca aggaatggaa gaagcattaa acagagccta
    11401 tgcttatgag gcagcaggag ctgatgccat tttgatccat tcaaaagaaa gtcagccaga
    11461 cgagattaag aatttcgtaa aacagttcac tggagcgata cctattgtga ttgtacctac
    11521 gacataccca catataaccg tgaaagaaat ggagttaatg ggcatcaata tggtcattta
    11581 cgccaatcat ggtcttagaa gctctattaa ggcaatgcaa gagacattct cccaaattct
    11641 ccttgatgga aatactgtag gtatagaaga taacattgtg tctatgaata ctgttttcga
    11701 gcttcaaggt atgtatgaaa tgagaaaaca agaagatatg tataactccg ccgcttctgt
    11761 catcagtact atcaaataaa taagatagga gtaaattaga atgatttcta atcaatatga
    11821 tattgtttca ctagcatatt tacattcgaa aattaatttt tttattgaac cgtcgttatc
    11881 attggaccat gtttttgatt ttttcagtac gcactttttt attaacaggg gaaggcatga
    11941 agaagatcgc ttggctgatg tgtatatcac tcgtaataaa gaagaattcc aaacggtaga
    12001 ctttaatagc ggtgatgata tttacatcag aaaaagtgct tctgaatatt tcaccattcc
    12061 ttgtaaacga gtaactgtta atggaattga atatgttaaa tgtacaaaaa cagatacgat
    12121 cttctcattt gatagagaaa acaagaagat aatcatttct acacagcttc ataatgcaga
    12181 gcaggataaa ctggttttaa ttgagttcgt tagagattta gtattgaaaa atgaagagaa
    12241 ccatggtgta gcggtgctgc acgctaccag tgcgttaaaa gatgccaagg ccactctcat
    12301 tattggctca aaagggaaag gcaagtcaac tctattgctg gaattagtga gtaaacaggg
    12361 gtacaaactc ataagcggtg ataagacttt tctttggata gaagatggga aattacgggc
    12421 ctcagggtgg ccggattatc ctcatttagg actcggcaca ctttctaaat atccagaatt
    12481 cgtcgaacat ttcgggctct ctaataaaat tgaatctatt aaagaaaatc tttggtcaac
    12541 tgaacataaa atggccattg acccggtttt ttttaagaag gtcattcctt ttgcagaacc
    12601 aggtcaatca tttatggtcg aatgtatgat ttaccctgat ctattccctt ctacagaatg
    12661 cagaatcaat caggtaagta atcatggtga attgattgtt ccgcatatag aaaggatttt
    12721 tacaaaagag aacacgatgt ggaaccattt tatttgtcct gtacatcaga atgaactgga
    12781 gagaaaaata aatcagtgta ttgagcttgc cggaaagttt tctgcttttg aagtgagtgg
    12841 atcaggcatt ttggaaggtt cagtgtttag cgagagatac gctctgtaat acctttaaaa
    12901 aacggtaaat aaaggagaaa aataaagtgg ttgaaatcac gattcaatca aaaggcttta
    12961 atcatagtta tgatattaca gaacaagtaa cagacgcatt atctcaatta gagccatctt
    13021 caggtttggt aaaggtctgt gtaaccggaa gtacggttgg tctcactgtc atgcgttatg
    13081 aaccaggcac cgtacaagac ttgctccaat gcttagagtc cattgcttca aagaataaac
    13141 agtacgaaca ctttaacact accggtgatt caaatggttt ttcacatgtg tggtctacaa
    13201 taattgggac aagtgtgatg gttccataca aaaatcataa gctggcctgt tcggacagcc
    13261 atagggtcgt attatttgat tttgatctaa gggaagcaga acgaaaaatc tatgtagatc
    13321 attaatgagg agttgtttga gatgaggaag ttacggatgg ctactccggg acctacgcaa
    13381 gttccgcagg aaattttatt ggcgggagca caggaaatga ttcatcaccg atcccggcaa
    13441 atggaggata ttattaacga aattaatcat gaactcccag atctattttt gacaaaacaa
    13501 gatatttata ttttgttatc ttcaggtacg ggtgccatgg aggcagctgt atcaaactcc
    13561 tttagtaggg gagataaagt tttagtcgta actaacggtt actttggaga gcgttttact
    13621 gatatctgta caatcttcgg tttagaggtg ataaccgtaa gctctccttg gggaacatct
    13681 gttaatattg aagaagttga aagagcgtat aagcagcatc cggatataaa gggagtgctc
    13741 gttgtttata gtgaaacttc aacgggtgct gtaaatgatg tagaggccat tggggcattg
    13801 ttcagagata cagaggtact ggtgatcgtt gatgctataa gcggccttat ttctcatgag
    13861 ctgtcaatgg atgattgggg attagacata gtgttagcag cctctcataa agggtttatg
    13921 atgccgccgg gcttagcgtt tgttgctatt tcaccgaaag cttgggaagt gattaataaa
    13981 attcaacctt caacttacta tttttcattt aaaagattta aaaagtttta tcctatggcg
    14041 ccttcaagtc cgggagtatc tttgctttta gctttgaaaa aatccttaga tttattgaag
    14101 gaagaaggcc tttcgaatgc taccagacga catgcccgta tcgctatggc gacacaaaga
    14161 ggattggagg ctttaggttt tcaccttttt gtacaatctc ctcatgttag aagtcataca
    14221 gtgacagcag cgttagcccc atcagggatt gatgcagctt tattattaaa aatactaaat
    14281 aaagaatatg ggcttacgat aactgggggg caaggtgagt ttaaagggaa gatgatcagg
    14341 attgggcata ttggagctgt tgatgaaatt gatttattcg gtatatttgg aatattggaa
    14401 caggtgttag cggaaatggg ttatcaggtt cattctgggg ccagcacgac tgctttgagt
    14461 gatgcattag gagggggagt catataccat gcttaaatta tatcaaaggg aaacctgtcc
    14521 ttattgcaaa ccggtaagag agaaattaac tgagctgaat ataacgtata tcaatgtgaa
    14581 tcttccgaag gatcgcgctt tacgaacaga attaatagaa aaaacaggcg ttccttatat
    14641 ccctgcttta attgatgaag aagataacgt tattatttca ggtagactgg aatacaacca
    14701 gcatgtctta gattatatag aaaaaaagtt tggccaaaat cgttaagggg gattcttctt
    14761 cttgcgctat gccttcataa cagatataca tgggaaacgt gataatcttg aaaaggtttt
    14821 ggagcatatc caaacctttt cttctataca tgagatcatt tgtttaggag atgtttttga
    14881 agttaaggtt cctaaaaagg atttaaaaga ttttcagttt cagtgtatgg aacaagtttt
    14941 agatttggat tggaaattaa tgaatttgct aaaagatatt cgagtgataa aaggcaatca
    15001 agaggagagg atattaagtc tgatccctga aaaagaactt ccgatagact tttacaactt
    15061 tttgattcac atgcctttag agattcattt aactccaatg gtcaggttaa cacatggcca
    15121 taattttgac tggacggaag aagaagagga ttattggagg cctggcaatg ttcattggaa
    15181 cagcccgtgg atcttttatg gtcataacca ccaaaatgta ctgtttgaag ttaagagtaa
    15241 agagaataac ccttattatg aacgaaaaag cattataaac ggtaagccga tcacattaga
    15301 ctctgaatct cgttatttaa tcaatatagg tgatatgaaa tatgatcatc ctagttggat
    15361 gcttttggat acattggaaa atcagattac ttacaatata ttgtattgaa aaggagttta
    15421 ttctgatgct tcgtatttta ctcattaatt ccgataaacc agagcctatt catttttttc
    15481 gaaaagataa ggaaacaaat gatactgtca atatatctgt cattacgaga tcgtgttatg
    15541 cctctcttta ttcacattgg gcagatcatg tatatatcgt tgatgatgta acagatttaa
    15601 cggttatgaa gagtttgatg ctggagatat taaaagtggg tccaattgat catattgtta
    15661 caacaaccga aaaaagtata ttaacaggtg ggtttcttcg ttcttatttt gggattgccg
    15721 gacctggatt tgaaacagct ctttatatga caaataaatt ggcgatgaag actaaactta
    15781 aaatggaagg gattcctgtt gcagactttt tgtgtttaag tcaagtaaaa gatatcccgg
    15841 cagcaggtga gaaactaggc tggcctatta ttgtaaagcc ggctcttggt tcaggtgcct
    15901 taaatacttt catgatccat tcattagatc attttgaaga cctgtattca gcttcgggtg
    15961 gtttaggcga attaaagaag aataactcac tgatgatcgc tgaaaaatgt atagaaatgg
    16021 aagagtttca ttgtgatact ttatacgctg acggagagat tctttttgta tcaatatcaa
    16081 aatatacagt gcctttgcta aaaggaatgg ctaaaatcca aggatcattt atattgagtc
    16141 aaaatgaccc ggtttatctt gaaatattag aacttcagag gtctgttgct cgagcatttc
    16201 gttttacgga cggccctggg catcttgaaa tttacagaac acgttcaggt gaattgatcg
    16261 tcggtgagat tgcaatgcgt atcgggggcg gtgggatcag ccgcatgata caaaaaaaat
    16321 tcaatatatc tttgtgggaa agttctctta acgtttctat aaatagagat ctaaacctca
    16381 tggtgaatcc aatagaggga actgtcggat actttagctt gccttgccga aacggaacaa
    16441 taaaagattt tacgcccact gaagactggg aaaagcttgc tggcatattg gaggttgaat
    16501 tgttatacca agaaggtgat gttgttgatg aaaagcaaag ttcaagtttt gatctggcca
    16561 gactttactt ttgtttagaa aatgagaatg aggtacaaaa cttattagca ttagtcaaac
    16621 aaacatatta tcttcatcta acagaggatc aaatgatgaa ccaataatct tcatttattt
    16681 agggcttcaa ttgaataagc tgttgtcgga agtgatgttt ttctttctcc cataaactat
    16741 atataatagg aagaaagaaa tggggtgatc agcatatgtt taaaaaaatc atcaaaacga
    16801 tcaagtacct ctcaggcagc tctagtgacc gatatcgcag acaccgacat tacagcagca
    16861 gccggcgcag acattaccgc agctacagca gcagctcagg caaaagaaga cactacgacc
    16921 gttatggcgg gagtcatcgt tacaaacgcc ggagctacag cagcagttaa tccaaaaaag
    16981 ttcttgttcc gcttttggga caagggtttt tttatgtgac cgattgaatg gcccgattta
    17041 catcttcgcg aatggaagcg gtgtgctgat actcttcatc aatgcccaat aattttttca
    17101 gcagcagggt tacttcgttt gtcagcgtta attcctccag ccaggtgccg tttttcttct
    17161 ttttcccttt atattgggag tacagcagga acaacagcgt ttctcccaga tcgaagaaat
    17221 catcctgttt tctcaccttt atttcctccg tttcttcagg agtcaattgc tttgcaaggc
    17281 cgaaatcgat gaggcagagc ctgccgtcat tgatgatgat attaggcgtt ctgatgtcgc
    17341 tgtgaaatat gaagcgatca tgcaggtatt ctacaattcc gagcagctgt gaaagcagct
    17401 gtaacgccat aagctctgta aacggctgtt ttcgaaaaaa caataattct tctatattct
    17461 ctccctcaat gagctgcatg acataataag cctgtccgtc tatgatgaaa ttttctatga
    17521 aggccgggat ttgcgggtgg tgaatgcttt tgagcagttt catttcctgc tggaaccgga
    17581 ctctttcttt ttcctttttc gcttttgtcg gccgcagctg ttttaagaca taagctgttt
    17641 gagtatggac atccgtgcaa gaatagacca agccatagcc gcccatgccg aggcattctt
    17701 cgattttgta ttgattattt aggataacgc cgtcccttag agggcggtca aaaagtagtt
    17761 tttttagctg ttttaatgcc atgtttgcac ttcccttggt tgtactgact atagtttacc
    17821 ttctaggcta agaataaaaa agagccggat aaccggctcg gtataagtta aaactgcttt
    17881 gtgacatcgt attcataatc tatttttgct tttacattac tcatcgtcga tctggcagtc
    17941 gctaatgtat tatatttaaa actccatacc tttgcgacac tgagttgatc tgacaatgat
    18001 atatcataag accctgaagt cgagctattt acaagtgcac gccgccattc attgttttcg
    18061 cttgtcatga tgaagtggcg cgtatttcct tggcttggtg tttgagtggc ggttgtttgg
    18121 actctggtta ctatggcgtc gtgcggtatt ccggattggt ttgttaaatc cgccttgatt
    18181 acgctggagt cagaacctga ggggctaagg gcggtatttc ctttattttc agcaacgccg
    18241 ttgaattgga acgttccgct gccggatttg atccgatttt caattgaaat tgtaaaatac
    18301 atgttcccgg tataggagcc gcgtgaaact ttcacataga aggtatccgt cgtgttttgg
    18361 gcgtcagcat tggcataaat aaaagaagaa aaagtggtgg ggctgatgac ttctgtgcct
    18421 tgtgaaacag gcgctctgtt cttatcgtaa atttcgattt tcatccccgt atacgcgctc
    18481 tggtatgtgc ttttcacgta tactttttct cccttattag ctgtaaaagt gaaataggct
    18541 tcatcctttc ctgcttccag tatcgttgta tcgatattct tatatttcca ataaccgatc
    18601 ggcattgcgg tatcaaatga attgtttcct gtgatagcag tgactccggc agctgatgcc
    18661 gaatacgtaa aggtgaataa gacagacagc ataatagcaa atggaataag ccattttttc
    18721 atcatgcaaa caacctcctt ttatttccat cttacataat aacgttttgt gtgtaaataa
    18781 atgttttttc aggttaatat atacattgtt actgccgata aaaaagagta agagagaatt
    18841 gttcaggagg gaatccaatg cgtctgaatc ggcaatttat ccgcacgcag atgttggcag
    18901 agaacatatt gaaaaaggat gcggctgtta aacgcgagaa aacgcctggg aatacagcgg
    18961 cggcgctaga caaggcatac ggcaggcttg agtcgcgatc tgcaaatgag ggaatcaatc
    19021 agttcaatta ttctaaaacc agcgtggcgg gaaacagcgg gactttcagc aaagtgtatc
    19081 aagcagcgaa tgttcgaaca gtgacagaca caggggcaga aacagtgatc gaatccacta
    19141 atccctatga atctgagagt gatatcagaa tcaaaatact agatgaaaaa tacagcagga
    19201 tcaatgcgat taacaaaaca aagcctgatc cattaggcta tattaaggat aagtaccaaa
    19261 attcaaagtc gccttatttt agaagtgatc tgtcagccgc agaaagacag gctgcttacg
    19321 ataatgaaac agagtggcta ttcaaaggga aggcgcaaaa ctataacttg caggatgccg
    19381 catttcgcaa tgttacgttt aatggagaag tggaggcaga gaatgctaag gtgtatcagc
    19441 ggagccaggt gaaccagcag ctgcaagtgc tgttgaaccg aaatcatatt catattccgg
    19501 aggggacagc gctgacgttt acgattacgc cgattgacta taaagtgcgg gtgagcggga
    19561 cagacgatga ggacctgatc aagcaaattg agcaagtgct gcaatctgga gacaacagca
    19621 aagaactatt tttacatatt atgaaaagcc aaagcagtga ttcaacacaa ttttccgaag
    19681 aggcttataa aaagtatcag gcggctcgtg agatgtacga agtcacaggc taccatttga
    19741 aggatttaga agtgattgac gggcggtatg taacgcctga tggacgtgac ttattagacg
    19801 tctataaaga agagcttgaa aaagatcctg tgcaaaaagc gacggccttg tatgcagttt
    19861 ctcactatcg ttcagagctc agtaaaattg cggaagcggg atatgatgcc attccggatt
    19921 tcattttatc aattgattac agcaatggat ctctgagaga tgtggggcag agcaagagct
    19981 atggcgccgg agataccgag tggcttgaca cattaaagcg tcaaaccggc gtgaattatt
    20041 agtaagctgt tcattgtgaa cagcttattt ttttatgaga atctaaaggg aaatatattt
    20101 taatatttaa ataatttaat tatatctata taaaagaatt taatcgaagt tttaataaaa
    20161 aactctgaac atatgtgttt acctgaaaaa aacaattgta ttttccagag aaatttatta
    20221 tgatgaaata agtaattttg gagattatat aacaatttta agttagaatt ttctgattgt
    20281 tataactgat tgatgagaag gcaagctggc ctgctgtttt ctcattttcg agtatttggt
    20341 taagaggagg aagaggagtg gcaaataaag aattaaagag gggcctgggc gcgcgtcata
    20401 ttcagatga
//
