LOCUS       NZ_CP033336            41176 bp    DNA     circular CON 03-APR-2024
DEFINITION  Streptococcus pyogenes strain TSPY165 chromosome, complete genome.
ACCESSION   NZ_CP033336
VERSION     NZ_CP033336.1
KEYWORDS    RefSeq.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1812036)
  AUTHORS   Macias,O.R., Shah,B.J., Hanson,B., Sanson,M.A. and Flores,A.R.
  TITLE     Complete genome sequences of group A Streptococcus emm types
            frequently associated with antibiotic resistance
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1812036)
  AUTHORS   Macias,O.R., Shah,B.J., Hanson,B., Sanson,M.A. and Flores,A.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2018) Pediatrics, UTHSC/McGovern Medical School,
            6431 Fannin St., MSB 3.130, Houston, TX 77030, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 10-JAN-2018
            Assembly Method :: Unicycler v. 0.4.6; Canu v. 1.7.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 263.0x
            Sequencing Technology :: Illumina MiSeq; Oxford Nanopore GridION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004124135.1-RS_2024_04_03
            Annotation Date                   :: 04/03/2024 02:58:46
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,798
            CDSs (total)                      :: 1,709
            Genes (coding)                    :: 1,656
            CDSs (with protein)               :: 1,656
            Genes (RNA)                       :: 89
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 31 of 53
            Pseudo Genes (incomplete)         :: 23 of 53
            Pseudo Genes (internal stop)      :: 18 of 53
            Pseudo Genes (multiple problems)  :: 17 of 53
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:19:50
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1095063
            Orig. end                         :: 1136239
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP033336.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Anthony R. Flores, MD, MPH,
            PhD.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..41176
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="T3PKS"
                     /region_number="3"
                     /rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /tool="antismash"
     cand_cluster    1..41176
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /kind="single"
                     /product="T3PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..41176
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:21176](+)"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..21176
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
     gene            complement(705..1355)
                     /locus_tag="EB817_RS05695"
                     /old_locus_tag="EB817_05705"
     CDS             complement(705..1355)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057640.1"
                     /locus_tag="EB817_RS05695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_05705"
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_003061805.1"
                     /transl_table=11
                     /translation="MINIPLMKDSLGFVLSGLPYTLGISLLSFFTGLFLGLGLALLGRS
                     RQPLIHYLVRAYISIMRGVPMIVVLFVLYFGLPYYGLELPALLCAYLGFSMVSAAYISE
                     VFRSSIEAIDKGQWEAAKALGLPYALMVKKIILPQAFRIAVPPLGNVIIDMVKSSSLAA
                     MITVPDIFQNAKIIGGREWDYMSMYILVAFIYWLIAFLLERYQEFLENKLALV"
     gene            complement(1384..2247)
                     /locus_tag="EB817_RS05700"
                     /old_locus_tag="EB817_05710"
     CDS             complement(1384..2247)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061079.1"
                     /locus_tag="EB817_RS05700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_05710"
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="WP_012560627.1"
                     /transl_table=11
                     /translation="MKKSVTLLSIGLASLLLAACAPHKSQKSSWDTIKEKGVLKVATPG
                     TYQPTSFYNDNNELVGYEVDMVKEIGKRLNIKVKFVETGFDQAFTSVDSGRVDISLNNF
                     DITPKRQKKYNISTPYKYGVGGMIVRADGSSNMVKKDLSDWKGKKAAGASGTEYMKVAQ
                     KQGAELVTYDNVTGDVYLNDVANGRTDFIPNDYPAQKLFVDYMLSQNPNLNVKMSDVQY
                     NPTEQGIVMNKKDDSLKKKIDAVIKDMIKDGSLKKISETYYAGQDLTKPFGKDKKIPVI
                     DTKDVN"
     gene            complement(2365..3819)
                     /locus_tag="EB817_RS05705"
                     /old_locus_tag="EB817_05715"
     CDS             complement(2365..3819)
                     /EC_number="3.5.1.4"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1105: amidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407508.1"
                     /locus_tag="EB817_RS05705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_05715"
                     /product="amidase"
                     /protein_id="WP_129304796.1"
                     /transl_table=11
                     /translation="MTYQDATAMAIAVQTGQTTPLELVTQAIYKAKKLNPTLNAITSER
                     FEAALEEAKQRDFSGLPFAGVPLFLKDLGQELKGHSSTSGSRLFKEYQATKTDLFVKRL
                     EALGFIILGRSNTPEFGFKNISDSSLHGPVNLPKDNTRNAGGSSGGAAALVSSGISALA
                     TASDGGGSIRIPASFNGLIGLKPSRGRMPVGPGSYRSWQGASVHFALTKSVRDTRNLLY
                     YLQMEQMESPFPLATLTKDSIYQSLQRPLTIAFYQRLSDGSPVSLDTAKALRQAVTWLR
                     EQGHQLVELEEFPVNMTEVIRHYYIMNSVETAAMFADIEDTFGRPMTKDDMETMTWAIY
                     QSGKDIPAWRYSQVLQKWDTYSATMASFHETYDLLLTFTTNTPAPKHGELVPDSKLMAN
                     LAQAEIFSSDEQFNLVETMFGKSLAINPYTALPNLTGQPAISLPTYETKEGLPMGIQLI
                     AAKGREDLLLGIAEQFEAAGLLKIPQ"
     gene            complement(4016..4645)
                     /gene="pyrE"
                     /locus_tag="EB817_RS05710"
                     /old_locus_tag="EB817_05720"
     CDS             complement(4016..4645)
                     /EC_number="2.4.2.10"
                     /GO_function="GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pyrE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922180.1"
                     /locus_tag="EB817_RS05710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_05720"
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="WP_002984920.1"
                     /transl_table=11
                     /translation="MTLASQIATQLLDIKAVYLKPEDPFTWASGIKSPIYTDNRVTLSY
                     PKTRDLIENGFVETIRAHFPEVEVIAGTATAGIPHGAIIADKMTLPFAYIRSKPKDHGA
                     GNQIEGRVLKGQKMVIIEDLISTGGSVLDAAAAASREGADVLGVVAIFTYELPKASQNF
                     KEAGIKLITLSNYTELIAVAKLQGYITNDGLHLLKKFKEDQVNWQQ"
     gene            complement(4703..5395)
                     /gene="pyrF"
                     /locus_tag="EB817_RS05715"
                     /old_locus_tag="EB817_05725"
     CDS             complement(4703..5395)
                     /EC_number="4.1.1.23"
                     /GO_function="GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA]"
                     /GO_process="GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="pyrF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984921.1"
                     /locus_tag="EB817_RS05715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_05725"
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="WP_002990139.1"
                     /transl_table=11
                     /translation="MKEERPIIALDFSSFEETKAFLDLFPAEEKLYVKIGMELYYAQGP
                     DIVRSIKSLGHNVFLDLKLHDIPNTVRAAMAVLKELDIDMATVHAAGGVEMLKAAREGL
                     GQGPTLIAVTQLTSTSEDQMRGDQNIQTSLLESVLHYSKGAAKAQLDGVVCSAQEVEAI
                     KAVTPTGFTCLTPGIRPKGSNIGDQKRVMTPNQARRIGSDYIVVGRPITQAKDPVAAYQ
                     AIKAEWAG"
     gene            complement(5672..6208)
                     /locus_tag="EB817_RS05720"
                     /old_locus_tag="EB817_05730"
     CDS             complement(5672..6208)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990141.1"
                     /locus_tag="EB817_RS05720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_05730"
                     /product="hypothetical protein"
                     /protein_id="WP_002984923.1"
                     /transl_table=11
                     /translation="MNVTEQNSHQILIQKLLVSIHYLTLFRDELKLVERTPSILGGEFP
                     AHLVQSELGDIVAAIDTLDMQQRLIESTFWYEESAFKLMNKTLDIVDNWIKGVDHLIDL
                     CQSKEVFQIIIGDKRIRVFGVLSDVFSSLKVSALSLKEAPIPDVLYEHIQRVNLEEEAF
                     IKYYQSPKVPTGEFE"
     gene            6430..7335
                     /locus_tag="EB817_RS05725"
                     /old_locus_tag="EB817_05735"
     CDS             6430..7335
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284709.1"
                     /locus_tag="EB817_RS05725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_05735"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_032462952.1"
                     /transl_table=11
                     /translation="MRIQQLHYIIKIVECGSMNEAAKQLFITQPSLSNAVKDLEMEMGI
                     TIFNRNPKGITLTKDGVEFLSYARQIIEQTSLLEDRYKNHNTGRELFSVSSQHYAFVVN
                     AFVSLLKRTDMTRYELFLRETRTWEIIDDVKNFRSEIGVLFINDYNRDVLTKLFDDNHL
                     TASPLFKAQPHIFVSKSNPLATKSLLSMDDLRDFPYLSYDQGIHNSFYFSEEMMSQMPH
                     NKSIVVSDRATLFNLMIGLDGYTVASGILNSNLNGDQIVAIPLDVPDEIDIIFIKHEKA
                     NLSKMGERFIEYLLEEVTFD"
     gene            complement(7415..8203)
                     /locus_tag="EB817_RS05730"
                     /old_locus_tag="EB817_05740"
     CDS             complement(7415..8203)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984926.1"
                     /locus_tag="EB817_RS05730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_05740"
                     /product="LytR family transcriptional regulator"
                     /protein_id="WP_129304798.1"
                     /transl_table=11
                     /translation="MTNNQTLDILLDVYAYNHAFRIAKALPNIPKTALYLLEMLKERRE
                     LNLAFLAEHAAENRTIEDQYHCSLWLNQSLEDEQIANYILDLEVKVKNGAIIDFVRSVS
                     PILYRLFLRLITSEIPNFKAYIFDTKNDQYDTWHFQAMLESDHEVFKAYLSQKQSRNVT
                     TKSLADMLTLTSLPQEIKDLGFLLRHFEKAVRNPLAHLIKPFDEEELHRTTHFSSQAFL
                     ENIITLATFSGVIYRREPFYFDDMNAIIKKELSLWRQSIV"
     gene            complement(8196..8909)
                     /gene="deoD"
                     /locus_tag="EB817_RS05735"
                     /old_locus_tag="EB817_05745"
     CDS             complement(8196..8909)
                     /EC_number="2.4.2.1"
                     /GO_function="GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0043096 - purine nucleobase salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="deoD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984928.1"
                     /locus_tag="EB817_RS05735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_05745"
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="WP_129304800.1"
                     /transl_table=11
                     /translation="MSIHISAKKGDIADKILLPGDPLRAKFIAENFLKDAVCFNEVRNM
                     FGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKTLIRVGTAGAIDPEVHVRELV
                     LAQAAATNSNIIRNDFPEFDFPQIADFGLLDKAYHIAREMGVTTHVGNVLSSDVFYTNM
                     PERNMALGKLGVKAIEMEAAALYYLAAQHHVKALGIMTISDNLNDPTEDTTAEERQTTF
                     TDMMKVGLETLIAND"
     misc_feature    9359..9372
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.2"
                     /tool="antismash"
     gene            complement(9572..10381)
                     /locus_tag="EB817_RS05740"
                     /old_locus_tag="EB817_05750"
     CDS             complement(9572..10381)
                     /EC_number="2.4.2.1"
                     /GO_function="GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647060.1"
                     /locus_tag="EB817_RS05740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_05750"
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="WP_115368170.1"
                     /transl_table=11
                     /translation="MSLMTKINETKDFLVTKGIETPEFGLILGSGLGELAEEVENAIVI
                     DYADIPNWGKSTVVGHAGKLVYGDLAGRKVLALQGRFHFYEGNPLEVVTFSVRVMKALG
                     CEGVLVTNAAGGIGYGPGTLMAITDHINMTGNNPLIGENLDEFGPRFPDMSDAYTKVYR
                     NKAHEVAEKMNIKLEDGVYMGLTGPTYETPAEIRAFKVLGADAVGMSTVPEVIVAAHSG
                     LKVLGISAITNFAAGFQSELNHEEVVEVTQHIKEDFKGLVKAILAEL"
     gene            complement(10365..10805)
                     /gene="arsC"
                     /locus_tag="EB817_RS05745"
                     /old_locus_tag="EB817_05755"
     CDS             complement(10365..10805)
                     /EC_number="1.20.4.1"
                     /GO_function="GO:0008794 - arsenate reductase
                     (glutaredoxin) activity [Evidence IEA]"
                     /GO_process="GO:0046685 - response to arsenic-containing
                     substance [Evidence IEA]"
                     /codon_start=1
                     /gene="arsC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922177.1"
                     /locus_tag="EB817_RS05745"
                     /note="This arsenate reductase requires both glutathione
                     and glutaredoxin to convert arsenate to arsenite, after
                     which the efflux transporter formed by ArsA and ArsB can
                     extrude the arsenite from the cell, providing resistance.;
                     This arsenate reductase requires both glutathione and
                     glutaredoxin to convert arsenate to arsenite, after which
                     the efflux transporter formed by ArsA and ArsB can extrude
                     the arsenite from the cell, providing resistance; Derived
                     by automated computational analysis using gene prediction
                     method: Protein Homology."
                     /old_locus_tag="EB817_05755"
                     /product="arsenate reductase (glutaredoxin)"
                     /protein_id="WP_010922177.1"
                     /transl_table=11
                     /translation="MEEITIYHNPNCGTSRNVLAMIRHAGIEPTIIEYLQTPPNRETLI
                     ELLQSMGISARELLRTNVPEFEAYGLANQAVAEKDIINAMLADPILINRPIVVTRKGVK
                     LCRPSETLLDILPVPLPSPYIKEDGESVNPIEVKGEKDVIDD"
     gene            complement(10821..12032)
                     /locus_tag="EB817_RS05750"
                     /old_locus_tag="EB817_05760"
     CDS             complement(10821..12032)
                     /EC_number="5.4.2.7"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008973 - phosphopentomutase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009117 - nucleotide metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184417.1"
                     /locus_tag="EB817_RS05750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_05760"
                     /product="phosphopentomutase"
                     /protein_id="WP_020905095.1"
                     /transl_table=11
                     /translation="MSKFNRIHLVVLDSVGIGAAPDADKFFNAGVADTDSDTLGHISET
                     AGLSVPNMAKIGLGNISRPIPLKTVPTEDNPTGYVTKLEEVSLGKDTMTGHWEIMGLNI
                     TEPFDTFWNGFPEEILTKIEEFSGRKIIREANKPYSGTAVIDDFGPRQMETGELIVYTS
                     ADPVLQIAAHEDIIPVEELYKICEYARSITLERPALLGRIIARPYVGEPGNFTRTANRH
                     DYAVSPFQDTVLNKLADAGVPTYAVGKINDIFNGSGITNDMGHNKSNSHGIDTLIKTLQ
                     LPEFTKGFSFTNLVDFDANFGHRRDPEGYRDCLHEFDNRLPEIIANMKEDDLLLITADH
                     GNDPTYAGTDHTREYIPLLAYSASFTGNGLIPQGHFADISATVAENFGVDTAMIGESFL
                     GHLK"
     gene            complement(12109..12792)
                     /gene="rpiA"
                     /locus_tag="EB817_RS05755"
                     /old_locus_tag="EB817_05765"
     CDS             complement(12109..12792)
                     /EC_number="5.3.1.6"
                     /GO_function="GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /gene="rpiA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881270.1"
                     /locus_tag="EB817_RS05755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_05765"
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="WP_115368169.1"
                     /transl_table=11
                     /translation="MEALKKIAGVTAAQYVTDGMTIGLGTGSTAYYFVEEIGRRVKQEG
                     LQVVGVTTSSVTSKQAEGLGIPLKSIDDIDSIDLTVDGADEVDKDFNGIKGGGAALLME
                     KIVATPTKEYIWVVDASKMVEHLGAFKLPVEVVQYGADRLFRVFEKAGYKPSFRMKGDS
                     RLVTDMQNYIIDLDLGCIKDPVAFGYLLDGTVGVVEHGLFNGMVDKVIVASKDGVTVLE
                     APTAG"
     misc_feature    complement(13026..13039)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 22.77"
                     /tool="antismash"
     gene            13170..15269
                     /locus_tag="EB817_RS05760"
                     /old_locus_tag="EB817_05770"
     CDS             13170..15269
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1223: ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922175.1"
                     /locus_tag="EB817_RS05760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_05770"
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="WP_129304802.1"
                     /transl_table=11
                     /translation="MTHFSGKDPFVNMDDIFNQLMANMGGYRSENPRYLVNGREITPEE
                     FQHYRQTGQLPVATTKATNSQMLTPKADSVLTQLGTNLTQEARQGHLDPVIGRNKEIQD
                     TAEILARRTKNNPVLVGDAGVGKTAVIEGLAQAIVNGDVPAAIKNKEIVSIDISSLEAG
                     TQYRGSFEETIQNLIQEVKEAGNIILFFDEIHQIVGAGATSSDSGSKGLADILKPALSR
                     GELTLIGATTQDEYRNTILKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQHHHIT
                     LPDNVLKAAVDYSIQYIPQRSLPDKAIDLLDMTAAHLAAQHPVTDLKTLETEIAKQKES
                     QEKAVAKEDFEKALAAKTRIETLQKQIEQHNQSQNVTATVNDIAESVERLTGIPVSNMG
                     TNDLERLKGISSRLKSHVIGQDEAVAAVARAIRRNRAGFDDGNRPIGSFLFVGPTGVGK
                     TELAKQLALDLFGSKDAIIRLDMSEYNDRTAVSKLIGTTAGYVGYDDNNNTLTERVRRN
                     PYAIVLLDEIEKADPQIITLLLQVLDDGRLTDGQGNTINFKNTVIIATSNAGFGQQDTE
                     TSESNIMDRIAPYFRPEFLNRFNSIIKFNHLQKESLEEIVDLMLAEVNQTTAKKGISLT
                     IADDAKAHLIDLGYNHAMGARPLRRIIEQEIRDRITDYYLDHPDVKKLQAILKEGQLVI
                     RQKDQ"
     gene            complement(15327..16070)
                     /locus_tag="EB817_RS05765"
                     /old_locus_tag="EB817_05775"
     CDS             complement(15327..16070)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984942.1"
                     /locus_tag="EB817_RS05765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_05775"
                     /product="hypothetical protein"
                     /protein_id="WP_002984942.1"
                     /transl_table=11
                     /translation="MTQVAQGRSKGKSLLCHQCNALFVFIIFLILLAVLFGVRYRNSSI
                     EGIWRTTSIDQKLGDDFAKRLTGLHQSPLIDDSLLTSSQMILTVKNNNVDLSFSVQVER
                     DIFVKRLAAYHQNELLKTLKENHLVVGDLSSKERQIIENSMPASHELEMILDQAFEKLA
                     SQIGGKYNQKTGHLSAVVLKGKVNRILHTIDIKEEVAAGHTSFSKGLLTPNGYFDYTRF
                     GKKLELLGDEKIIFKKALKKSPSSV"
     gene            complement(16218..16817)
                     /gene="yihA"
                     /locus_tag="EB817_RS05770"
                     /old_locus_tag="EB817_05780"
     CDS             complement(16218..16817)
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0043022 - ribosome binding [Evidence IEA]"
                     /GO_process="GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="yihA"
                     /gene_functions="other (smcogs) SMCOG1227: ribosome
                     biogenesis GTP-binding protein YsxC"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054379.1"
                     /locus_tag="EB817_RS05770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_05780"
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="WP_011184414.1"
                     /transl_table=11
                     /translation="MAEEQVLNTHNASILLSAANKSHYPQDDLPEIALAGRSNVGKSSF
                     INTILGRKNLARTSSKPGKTQLLNFFNIDNKLRFVDVPGYGYAKVSKSERAKWGKMIEE
                     YLTSRDNLRAVVSLVDLRHAPSKEDIQMYDFLKYYDIPVIVVATKADKIPRGKWNKHES
                     VVKKALNFDKSDTFIVFSSVERIGIDDSWDAILEQV"
     gene            complement(16827..18056)
                     /gene="clpX"
                     /locus_tag="EB817_RS05775"
                     /old_locus_tag="EB817_05785"
     CDS             complement(16827..18056)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="clpX"
                     /gene_functions="other (smcogs) SMCOG1223: ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984948.1"
                     /locus_tag="EB817_RS05775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_05785"
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="WP_002984948.1"
                     /transl_table=11
                     /translation="MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEI
                     IKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDRAKRALSVAVYNHYKRVSFTESRDD
                     DDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENILLK
                     LIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVP
                     PQGGRKHPNQEMIQIDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASY
                     MQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIQILTEPRNALVKQYQALLSYDG
                     VELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVE
                     GKSKPVLETA"
     gene            complement(18186..18356)
                     /locus_tag="EB817_RS05780"
                     /old_locus_tag="EB817_05790"
     CDS             complement(18186..18356)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302775.1"
                     /locus_tag="EB817_RS05780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_05790"
                     /product="hypothetical protein"
                     /protein_id="WP_002990165.1"
                     /transl_table=11
                     /translation="MQRSIFGVFTAFLCVICVLCAIPAFKKNRYGLGSLFLLNAFTNLV
                     NSIHAFYGTLF"
     gene            complement(18376..18873)
                     /locus_tag="EB817_RS05785"
                     /old_locus_tag="EB817_05795"
     CDS             complement(18376..18873)
                     /EC_number="1.5.1.3"
                     /GO_function="GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005542 - folic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984955.1"
                     /locus_tag="EB817_RS05785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_05795"
                     /product="dihydrofolate reductase"
                     /protein_id="WP_002984955.1"
                     /transl_table=11
                     /translation="MTKEIIAIWAEDEAGLIGVAGKLPWYLPKELEHFKKTTLHQAILM
                     GRVTFEGMNCKRLPQRQTLVMTRNRDYQVDEVLTMTSIEKVLEWYHAQDKTLYIIGGNK
                     VLEAFNGYFDRIIKTVIHHRFKGDTYRPNLDFSHFTQESQTFYARDAKNPYDFTVTALK
                     HK"
     gene            complement(18953..19792)
                     /locus_tag="EB817_RS05790"
                     /old_locus_tag="EB817_05800"
     CDS             complement(18953..19792)
                     /EC_number="2.1.1.45"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /locus_tag="EB817_RS05790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_05800"
                     /product="thymidylate synthase"
                     /protein_id="WP_011017679.1"
                     /transl_table=11
                     /translation="MTKADQIFKANIQKIINEGSLSEQARPKYKDGRTAHSKYITGAFA
                     EYDLAKGEFPITTLRPIPIKSAIKELFWIYQDQSNSLDVLEAKYNVHYWNEWEVDQTRT
                     IGQRYGAVVKKHDIISKILKQLAENPWNRRNVISLWDYEAFEETKGLLPCAFQIMFDVR
                     RVGEDLYLDASLTQRSNDILVAHHINAMQYVALQMMIAKHFGWKIGKFFYFVNNLHIYD
                     NQFDQAQELLKRQPVASQPKLVLNVPDGTNFFDIKPDDFELQNYDPVKPQLHFDLAI"
     misc_feature    complement(19748..19762)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 23.77"
                     /tool="antismash"
     gene            20001..21176
                     /locus_tag="EB817_RS05795"
                     /old_locus_tag="EB817_05805"
     CDS             20001..21176
                     /EC_number="2.3.3.10"
                     /GO_function="GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043: hydroxymethylglutaryl-CoA synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993959.1"
                     /locus_tag="EB817_RS05795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_05805"
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="WP_014407506.1"
                     /sec_met_domain="Chal_sti_synt_N (E-value: 8.6e-07,
                     bitscore: 25.3, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIGIDKIGFATSQYVLKLEDLALARQVDPAKFSQGLLIESFSVA
                     PITEDIITLAASAADQILTDEDRAKIDMVILATESSTDQSKASAIYVHHLVGIQPFARS
                     FEVKQACYSATAALDYAKLHVASKPDSRVLVIASDIARYGVGSPGESTQGSGSIALLVT
                     ANPRILALNKDNVAQTRDIMDFWRPNYSFTPYVDGIYSTKQYLNCLETTWQAYQKRENL
                     QLSDFAAVCFHIPFPKLALKGLNNIMDNTVPPEHREKLIEAFQASITYSKQIGNIYTGS
                     LYLGLLSLLENSKVLQSGDKIGFFSYGSGAVSEFYSGQLVAGYDKMLMTNRQALLDQRT
                     RLSVSKYEDLFYEQVQLDDNGNANFDIYLTGKFALTAIKEHRRIYHTNDKN"
     gene            21163..22440
                     /locus_tag="EB817_RS05800"
                     /old_locus_tag="EB817_05810"
     CDS             21163..22440
                     /EC_number="1.1.1.88"
                     /GO_function="GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA]"
                     /GO_process="GO:0016054 - organic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1187: hydroxymethylglutaryl-CoA reductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880299.1"
                     /locus_tag="EB817_RS05800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_05810"
                     /product="hydroxymethylglutaryl-CoA reductase, degradative"
                     /protein_id="WP_010922170.1"
                     /transl_table=11
                     /translation="MTKTNLNWSGFSKKTFEERLQLIEKFKLLNAENLNQLKTDVLLPI
                     QTANQMTENVLGRLALPFSIAPDFLVNGSTYQMPFVTEEPSVVAAASFAAKLIKRSGGF
                     KAQTLNRQMIGQIVLYDIDQIDNAKAAILHKTKKLIALANKAYPSIVKRGGGARTIHLE
                     EKGEFLIFYLTVDTQEAMGANMVNTMMEALVPDLTRLSKGHCLMAILSNYATESLVTTS
                     CEIPVRLLDHDKTKSLQLAQKIELASRLAQVDPYRATTHNKGIFNGIDAVVIATGNDWR
                     AIEAGAHAYASRNGSYQGLSQWHFDQDKQVLLGQMTLPMPIASKGGSIGLNPTVSIAHD
                     LLNQPDAKTLAQLIASVGLAQNFAALKALTSSGIQAGHMKLHAKSLALLAGATQDEIAP
                     LVNALLADKPINLEKAHFYLSQLRQS"
     gene            complement(22670..23659)
                     /gene="fni"
                     /locus_tag="EB817_RS05805"
                     /old_locus_tag="EB817_05815"
     CDS             complement(22670..23659)
                     /EC_number="5.3.3.2"
                     /GO_function="GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="fni"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984966.1"
                     /locus_tag="EB817_RS05805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_05815"
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="WP_010922169.1"
                     /transl_table=11
                     /translation="MTNRKDDHIKYALKYQSPYNAFDDIELIHHSLPSYDLSDIDLSTH
                     FAGQDFDFPFYINAMTGGSQKGKAVNEKLAKVAAATGIVMVTGSYSAALKNPNDDSYRL
                     HEVADNLKLATNIGLDKPVALGQQTVQEMQPLFLQVHVNVMQELLMPEGERVFHTWKKH
                     LAEYASQIPVPVILKEVGFGMDVNSIKLAHDLGIQTFDISGRGGTSFAYIENQRGGDRS
                     YLNDWGQTTVQCLLNAQGLMDQVEILASGGVRHPLDMIKCFVLGARAVGLSRTVLELVE
                     KYPTERVIAIVNGWKEELKIIMCALDCKTIKELKGVDYLLYGRLQQVN"
     gene            complement(23646..24659)
                     /locus_tag="EB817_RS05810"
                     /old_locus_tag="EB817_05820"
     CDS             complement(23646..24659)
                     /EC_number="2.7.4.2"
                     /GO_function="GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016126 - sterol biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635411.1"
                     /locus_tag="EB817_RS05810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_05820"
                     /product="phosphomevalonate kinase"
                     /protein_id="WP_014407504.1"
                     /transl_table=11
                     /translation="MSNYCVQTGGKLYLTGEYAILTPGQKALIHFIPLMMTAEISPAAH
                     IQLASDMFAHKAGMTPDASYALIQATVKTFADYLGQSIDQLEPFSLIITGKMERDGKKF
                     GIGSSGSVTLLTLKALSAYYQITLTPELLFKLAAYTLLKQGDNGSMGDIACIAYQTLVA
                     YTSFDREQVSNWLQTMPLKKLLVKDWGYHIQVIQPALPCDFLVGWTKIPAISRQMIQQV
                     TASITPAFLRTSYQLTQSAMVALQEGHKEELKKSLAGASHLLKELHSAIYHPKLVTLVA
                     ACQKQDAVAKSSGSGGGDCGIALAFNQNARDTLISKWQEADIALLYQERWGENDQP"
     gene            complement(24652..25596)
                     /gene="mvaD"
                     /locus_tag="EB817_RS05815"
                     /old_locus_tag="EB817_05825"
     CDS             complement(24652..25596)
                     /EC_number="4.1.1.33"
                     /GO_function="GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA]"
                     /GO_process="GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /gene="mvaD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888980.1"
                     /locus_tag="EB817_RS05815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_05825"
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="WP_014407503.1"
                     /transl_table=11
                     /translation="MDPNVITVTSYANIAIIKYWGKENQAKMIPSTSSISLTLENMFTT
                     TSVSFLPDTATSDQFYINGVLQNDEEHTKISAIIDQFRQPGQAFVKMETQNNMPTAAGL
                     SSSSSGLSALVKACDQLFDTQLDQKALAQKAKFASGSSSRSFFGPVAAWDKDSGAIYKV
                     ETDLKMAMIMLVLNAAKKPISSREGMKLCRDTSTTFDQWVEQSAIDYQHMLTYLKTNNF
                     EKVGQLTEANALAMHATTKTANPPFSYLTKESYQAMEAVKELRQEGFACYFTMDAGPNV
                     KVLCLEKDLAQLAERLGKNYRIIVSKTKDLPDV"
     gene            complement(25578..26456)
                     /gene="mvk"
                     /locus_tag="EB817_RS05820"
                     /old_locus_tag="EB817_05830"
     CDS             complement(25578..26456)
                     /EC_number="2.7.1.36"
                     /GO_function="GO:0004496 - mevalonate kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016126 - sterol biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /gene="mvk"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054375.1"
                     /locus_tag="EB817_RS05820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_05830"
                     /product="mevalonate kinase"
                     /protein_id="WP_002984974.1"
                     /transl_table=11
                     /translation="MNENIGYGKAHSKIILIGEHAVVYGYPAIALPLTDIEVVCHIFPA
                     DKPLVFDFYDTLSTAIYAALDYLQRLQEPIAYEIVSQVPQKRGMGSSAAVSIAAIRAVF
                     SYCQEPLSDDLLEILVNKAEIIAHTNPSGLDAKTCLSDHAIKFIRNIGFETIEIALNGY
                     LIIADTGIHGHTREAVNKVAQFEETNLPYLAKLGALTQALERAINQKNKVAIGQLMTQA
                     HSALKAIGVSISKADQLVEAALRAGALGAKMTGGGLGGCMIALADTKDMAEKISHRLKE
                     EGAVNTWIQML"
     gene            complement(26750..27982)
                     /locus_tag="EB817_RS05825"
                     /old_locus_tag="EB817_05835"
     CDS             complement(26750..27982)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888981.1"
                     /locus_tag="EB817_RS05825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_05835"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_002990181.1"
                     /transl_table=11
                     /translation="MFNRIRIRFIMIASIAIFIILSSIVGIINTARCYQSQQEINRILH
                     LISSNKGKLPGTTESSKRLGTKLSEDSLSQFRYYSVIFNANGHLLSSNTANISALDREE
                     AQYFARLFAKSGEEKGSYRHQDSVYSYLITQLPNEEKLVVILDTTFYFRSVGDLLAVSM
                     MLAFGGFIFFVVLVSLFSGMVIKPFVQNYEKQRRFITNAGHELKTPLAIISANNELVEL
                     MTGESEWTKSTSDQVKRLTGLINQMITLARLEEQPDVVLHMVDFSAIAQDAAEDFKSLV
                     LKDGKRFDLTIQPNIMIKAEEKSLFELVTILVDNANKYCDPKGLVKVSLTTIGRRRKRA
                     KLEVSNTYLEGKSIDYSRFFERFYREDESHNSKEKGYGIGLSMAESMVKLFKGTITVNY
                     KNDAIVFTVVI"
     gene            complement(27991..28659)
                     /locus_tag="EB817_RS05830"
                     /old_locus_tag="EB817_05840"
     CDS             complement(27991..28659)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984985.1"
                     /locus_tag="EB817_RS05830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_05840"
                     /product="response regulator transcription factor"
                     /protein_id="WP_002984985.1"
                     /transl_table=11
                     /translation="MKILLAEDEWQMSNVLTTAMTHQGYDVDVVFNGQEAIDKAKDNAY
                     DIMILDIMMPIKSGIEALKEIRASGNCSHIIMLTAMAEINDRVTGLDAGADDYLTKPFS
                     LKELLARLRSMERRVESFTPQVLQFAGVTLNINEQELSAGNAIRLASKEGKLMAFLMLN
                     QGKYLDTKTLYQHVWSDQEDYDTSIVWVYISYLRQKLLAIQANVIIAGDKDTSYCLLEK
                     "
     gene            complement(28662..29312)
                     /locus_tag="EB817_RS05835"
                     /old_locus_tag="EB817_05845"
     CDS             complement(28662..29312)
                     /GO_process="GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984988.1"
                     /locus_tag="EB817_RS05835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_05845"
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="WP_002984988.1"
                     /transl_table=11
                     /translation="MKERLEHYSTSSIYSGFEVYLPLVLQTITDVIIAENIKSKKETGF
                     KLYEHFTSRIKSEASMIEKCQRKQLPLTSKSALKIIKDSIGIRIICGFIDDIYRMVDLL
                     KSIPGMSVNTEKDYILNAKPNGYRSYHLILELETHFPDILGEKKGCYFIEVQLRTIAQD
                     SWASLEHQMKYKHQVANAEMITRELKRCADELASCDVTMQTIRQLIQETTEEE"
     misc_feature    29448..29461
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.6"
                     /tool="antismash"
     misc_feature    29527..29540
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.3"
                     /tool="antismash"
     misc_feature    complement(29528..29541)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.93"
                     /tool="antismash"
     gene            29532..31544
                     /locus_tag="EB817_RS05840"
                     /old_locus_tag="EB817_05850"
     CDS             29532..31544
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1283: 2`,3`-cyclic-nucleotide 2`-phosphodiesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888982.1"
                     /locus_tag="EB817_RS05840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_05850"
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="WP_129304804.1"
                     /transl_table=11
                     /translation="MKKYFILKSSVLSILTSFTLLVTDVQADQVDVQFLGVNDFHGALD
                     NTGTAYTPSGKIPNAGTAAQLGAYMDDAEIDFKQANQDGTSIRVQAGDMVGASPANSAL
                     LQDEPTVKVFNKMKFEYGTLGNHEFDEGLDEFNRIMTGQAPDPESTINDITKQYEHEAS
                     HQTIVIANVIDKKTNDIPYGWKPYAIKDIAINDKIVKIGFIGVVTTEIPNLVLKQNYEH
                     YQFLDVAETIAKYAKELQEQHVHAIVVLAHIPATSKDGVVDHEMATVMEKVNQIYPEHS
                     IDIIFAGHNHQYTNGTIGKTRIVQALSQGKAYADVRGTLDTDTNDFIKTPSANVVAVAP
                     GIKTENSDIKAIINHANDIVKTVTERKIGTATNSSTISKTENIDKESPVGNLVTTAQLT
                     IAKKTFPTVDFAMTNNGGIRSDLVVKNDRTITWGAAQAVQPFGNILQVIQMTGQHIYDV
                     LNQQYDENQTYFLQMSGLTYTYTDNDPKNSDTPFKIVKVYKDNGEEINLTTTYTVVVND
                     FLYGGGDGFSAFKKAKLVGAINTDTEAFITYITNLQASGKTVNATIKGVKNYVTSNLES
                     STKINSAGKHSIISKVFRNRDGNIVSSEVISDLLTSTENTNNSLGKKETTINKNTISSS
                     TLPITGENYKMSPIMTILALISLGGLNAFIKKRKS"
     misc_feature    complement(29543..29556)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.33"
                     /tool="antismash"
     gene            complement(31626..32036)
                     /locus_tag="EB817_RS05845"
                     /old_locus_tag="EB817_05855"
     CDS             complement(31626..32036)
                     /EC_number="3.5.1.88"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017671.1"
                     /locus_tag="EB817_RS05845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_05855"
                     /product="peptide deformylase"
                     /protein_id="WP_129284083.1"
                     /transl_table=11
                     /translation="MIREIITDHFLLQQKAQVAKKEDLWIGQDLQDTLAFYRQECLGMA
                     ANMIGEQKRIVIVSMGFIDLVMFNPVMVSKKGIYQTKESCLSLYGYRKTQRYDKITVEY
                     LDHNWRPKRLSLTGLTAQICQHELDHLEGILI"
     gene            complement(32292..32510)
                     /locus_tag="EB817_RS09475"
                     /old_locus_tag="EB817_05860"
     CDS             complement(32292..32510)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995561.1"
                     /locus_tag="EB817_RS09475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_05860"
                     /product="hypothetical protein"
                     /protein_id="WP_011285486.1"
                     /transl_table=11
                     /translation="MALLFYYYVRKNQVKKLSQLKNLTEIFRKFIILTINNISAIKAFQ
                     TAGVLFGPIKAANARESSIWFENLTKQ"
     gene            complement(32927..34804)
                     /locus_tag="EB817_RS05860"
                     /old_locus_tag="EB817_05870"
     CDS             complement(32927..34804)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922163.1"
                     /locus_tag="EB817_RS05860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_05870"
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="WP_129304806.1"
                     /transl_table=11
                     /translation="MSHFLVEKLTKTVGDKTVFQDISFIIHDFDRIGIIGVNGTGKTTL
                     LDVLSGRLGFDGDHSPFSKANDYKIAYLTQDPEFNDAASVLDTVLSADVKAIQLIRQYE
                     LLMANYTEDKQESLESLMSEMDRLDAWSIESDVKTVLSKLGITDLEQKVGDLSGGMRRR
                     VQLAQVLLGAADLLLLDEPTNHLDIDTIAWLTTYLKTAKKTVLFITHDRYFLDHVATRI
                     FELDKAGLTEYQGNYQDYVRLKAEQDERDATNLHKKKQLYKQELAWMRTQPQARATKQQ
                     ARINRFTDLKKEVHQDSSADKLEMAFETSRIGKKVIHFEDLSFAYGDRQLIKDFNLIIQ
                     NKDRIGIVGDNGVGKSTLLNIINGDLKPTSGKLDIGDTIRVGYFSQQLKDMDETKRVIN
                     YLQEVADEVKTSVGTTSISELLEQFLFPRSSHGTLIAKLSGGEKKRLYLLKLLIEKPNV
                     LLLDEPTNDLDIATLTVLENFLANFAGPVITVSHDRYFLDKVATKILAFEEGDIRIFYG
                     NYSDYLDEKAFEKETVEADLAKAIVTEEVPLPPKEEKKRMSYLEKQEWAQIEDKIATIE
                     ANIEEIENQMLTVVSDYGQLAQLQKELDQRNNDLLLAYERFEYLSGLDI"
     gene            complement(34801..36009)
                     /locus_tag="EB817_RS05865"
                     /old_locus_tag="EB817_05875"
     CDS             complement(34801..36009)
                     /EC_number="2.7.7.72"
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880307.1"
                     /locus_tag="EB817_RS05865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_05875"
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="WP_164976432.1"
                     /transl_table=11
                     /translation="MKLMTMPSEFQKALPILTKIKEAGYEAYFVGGSVRDILLGRPIHD
                     VDIATSSYPEETKAIFNRTVDVGIEHGTVLVLENGGEYEITTFRTEDVYVDYRRPSQVS
                     FVRSLEEDLKRRDFTVNALALDENGQVIDKFRGLIDLKQKRLRAVGKAEERFEEDALRI
                     MRGFRFAASLDFDIEATTFEAMRSHSPLLEKISVERSFTEFDKLLMAPHWRKGISAMIA
                     CQAYDYLPGLKQQEAGLNHLIVSLKDNFTFSDHHQAWAYVMISLAIEDPKSFLKAWKTS
                     NDFQRYVTKLIALYRIRQERSFEKLDIYQYGKKMASLVEDLRKAQSLSVDMDHINTLDQ
                     ALVIHDKHDIVLNGSHLIKDFGMKPGPQLGLMLEKVELAIVEGRLDNDFTTIEAFVREE
                     LAT"
     gene            complement(36134..36982)
                     /locus_tag="EB817_RS05870"
                     /old_locus_tag="EB817_05880"
     CDS             complement(36134..36982)
                     /GO_function="GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985007.1"
                     /locus_tag="EB817_RS05870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_05880"
                     /product="DegV family protein"
                     /protein_id="WP_002990194.1"
                     /transl_table=11
                     /translation="MKLAVITDSTATLPTDLKQDKAIFSLDIPVIIDDETYFEGRNLSI
                     DDFYQKMADSQNLPKTSQPSLSELDNLLGLLSSKGYTHVIGLFLAGGISGFWQNIQFLA
                     EEHPEIEMAFPDSKITSAPLGSMVKNVLDWSRQGMTFQAILNKLQEQIDGTTAFIMVDD
                     LNHLVKGGRLSNGSALLGNLLSIKPILRFDEEGKIVVYEKVRTEKKAMKRLVEILNDLI
                     ADGQYNVSIIHSKAQDKADYLKRLLQDSGYQYDIEEVHFGAVIATHLGEGAIAFGVTPR
                     L"
     gene            complement(36982..37362)
                     /locus_tag="EB817_RS05875"
                     /old_locus_tag="EB817_05885"
     CDS             complement(36982..37362)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985011.1"
                     /locus_tag="EB817_RS05875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_05885"
                     /product="DUF1149 family protein"
                     /protein_id="WP_002985011.1"
                     /transl_table=11
                     /translation="MQLVREKEFVNQYHYDARNLEWEKENGTPETNFEVTFQLIDKDEQ
                     QKETVIVSVLQFVIVKEEFVISGVISQMVRILDRLVDKPSEFTQEEVESLAAPLLDMVK
                     RLTYEVTEIALDRPGIHLEFKN"
     misc_feature    complement(38189..38202)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.36"
                     /tool="antismash"
     misc_feature    38233..38246
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.62"
                     /tool="antismash"
     gene            38269..39294
                     /locus_tag="EB817_RS05885"
                     /old_locus_tag="EB817_05895"
     CDS             38269..39294
                     /EC_number="3.4.22.-"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922160.1"
                     /locus_tag="EB817_RS05885"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases.; This family includes IgM or IgG-cleaving
                     cysteine proteases.; This family includes IgM or
                     IgG-cleaving cysteine proteases; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="EB817_05895"
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="WP_129304808.1"
                     /transl_table=11
                     /translation="MRKRCYSTSAAVLAAVTLFALSVDRGVIADSFSANQEIRYSEVTP
                     YHVTSVWTKGVTPPAKFTQGEDVFHAPYVANQGWYDITKTFNGKDDLLCGAATAGNMLH
                     WWFDQNNEKIEAYLKKHPDKQKIMFGDQELLDVRKVINTKGDQTNSELFNYFRDKAFPG
                     LSARRIGVMPDLVLDMFINGYYLNVYKTQTTDVNRTYQEKDRRGGIFDAVFTRGDQSKL
                     LTSRHDFKEKNLKEISDLIKKELTEGKALGLSHTYANVRINHVINLWGADFDSNGNLKA
                     IYVTDSDSNASIGMKKYFVGVNSAGKVAISAKEIKEDNIGAQVLGLFTLSTGQDSWNQT
                     N"
     gene            39413..39679
                     /locus_tag="EB817_RS05890"
                     /old_locus_tag="EB817_05900"
     CDS             39413..39679
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014875.4"
                     /locus_tag="EB817_RS05890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_05900"
                     /product="exotoxin beta-grasp domain-containing protein"
                     /protein_id="WP_269458357.1"
                     /transl_table=11
                     /translation="MDKDIVTIQEFDFKIRKFLMESKEIHLTKSPYIRGSLEIHSKNRK
                     HEKINLYDAKPNSTRSDVFKKYKDNKTINMKDFSHFDIYLWTK"
     gene            <39877..40194
                     /locus_tag="EB817_RS05895"
                     /old_locus_tag="EB817_05905"
                     /pseudo=""
     CDS             <39877..40194
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /locus_tag="EB817_RS05895"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="EB817_05905"
                     /product="IS3 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="KCYDGTI"
     gene            complement(40251..40958)
                     /locus_tag="EB817_RS05900"
                     /old_locus_tag="EB817_05910"
     CDS             complement(40251..40958)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990206.1"
                     /locus_tag="EB817_RS05900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_05910"
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="WP_002990206.1"
                     /transl_table=11
                     /translation="MTKKKGKLVLISLFVLAACLGAYSAMRQSHKTSNVSAETIASSST
                     RHFIDEIGPTASTIGQERDLYASVMIAQAILESSNGKSSLSQAPYYNFFGIKGAYNGSS
                     VTMSTWEDDGNGNTYTIDQAFRAYPSIADSLNDYADLLSSSTYIGARKSNTLSYQDATA
                     ALTGLYATDTSYNLKLNNIIATYGLTAYDVANSSAQETGLATSGYVWNEYRRNYTDAET
                     LAVDEAWAKRMTY"
ORIGIN
        1 ccacgataag atgacaaagg gcttggatga gggctctcga tgatgtggtg ctttggatta
       61 gtaatgaagg cttttttctt ccttgcataa gctccccaca aaatgaaaac tacagggatg
      121 tctttctcat tcagcacttt aataacagcg tctgtaaatg gctcccatat taagcctgca
      181 tgcccattag cctggcctgc tggcactgtt aagcaagcat tcaaaagcag aaccccttga
      241 ctagcccaag tgcttaaatc atgatggtca cgaggaccaa tgtcatcagc taattctttt
      301 aaaatattaa taagggatgg cggagcagaa atctcttctg gaactgaaaa tgataagccc
      361 tgggcctgtt tggggccatg ataagggtct tgtcctaaaa tcaacacttt ggtttcttcc
      421 aaaggagtga cttgtaaagc tttaaagaca ttttctcgtg gaggatagac aagaccggaa
      481 gcataggctt catctaaaaa gtgattgatg cgaccgtagt aatgctccgg caaaaatgat
      541 ttgattttct catgccaaat tgaatgagcc ataagattcc tttctaatca cgtcagtttc
      601 taagttaaat acgatgtcct tttctatcta gtttaccaca ttttaaatag aaagaccctg
      661 aaaatatgat atttccaggg ttaatattcg ttttttacag gatattaaac aagtgctagc
      721 ttattttcta agaattcttg gtaacgttct aacaaaaaag caataagcca atagataaag
      781 gctactaaaa tatacatgga catgtaatcc cactctctac cgccaataat tttggcattt
      841 tgaaaaatat ctggtacggt aatcatggca gctagcgacg aacttttaac catatcaata
      901 atgacattgc ctagaggagg aactgcaatt cgaaaagctt gaggaagaat aattttctta
      961 accataagag catatggcaa ccctaaagcc ttagctgctt cccactgtcc cttgtcaata
     1021 gcttctatag aagagcgaaa aacttcagaa atataggcag cgctaaccat agaaaaacca
     1081 agataagcgc aaagtaaagc tggcaattct aaaccataat aaggcaaccc gaaataaaga
     1141 acaaagagca ccacgatcat cggcacacct cgcataatag agatgtacgc tctaacaaga
     1201 taatgaatca acggctgacg tgaccttccc agaagggcta ggcctaaacc taaaaacaga
     1261 cccgtaaaaa aactgagcaa cgaaatacca agggtataag gtaatcccga taacacaaat
     1321 cctaaactat ctttcattaa tgggatatta atcatgtggt taggactcct ttaacatcaa
     1381 gtattagtta acgtctttcg tatcaatgac gggaattttt ttgtctttgc caaaaggttt
     1441 tgtcagatct tgaccagcat agtaggtttc agagattttc ttcaagctac catcttttat
     1501 catgtcttta ataacagcat ctattttttt cttgaggcta tcgtcttttt tgttcataac
     1561 aattccttgt tcggttgggt tgtactgaac atcgctcatt ttgacattta gatttggatt
     1621 ttgagataac atgtaatcca caaataattt ttgagctggg taatcatttg gaatgaaatc
     1681 tgttcgaccg ttagccacat cgtttagata aacatctcct gtaacattat cgtaggtcac
     1741 cagttcagct ccctgttttt gcgctacttt catgtattct gttccagaag caccagctgc
     1801 tttttttcct ttccagtcgc taagatcttt tttaaccatg tttgagctgc catcagcacg
     1861 gacaatcatg cctcctaccc cgtatttata aggcgtagag atattgtatt ttttctgacg
     1921 ttttggggta atgtcaaagt tgttcaaaga aatatccact cgaccactat caactgaggt
     1981 aaacgcttgg tcaaatcctg tttcaacaaa cttgacttta atgttaagtc gtttaccgat
     2041 ttctttgacc atatctactt cgtaacctac taactcatta ttatcgttgt aaaaagaagt
     2101 tggctgatag gttcctgggg tagctacttt taacacccct ttttctttga tagtgtccca
     2161 acttgatttt tgagatttat gtggcgcaca tgctgccaat aaaaggctgg caagtccgat
     2221 agacagtaaa gtaactgatt tcttcatagt aactccttta ttaagataag aatagtataa
     2281 cattttgatt aagttgtgtt atcagtgagc gctcaatctc tttaaaaagt taatctataa
     2341 tagttaaact gttttataag attattattg aggaatcttc aataatcctg ctgcctcaaa
     2401 ctgctctgca attcctaata ataggtcctc tctacctttg gctgcaatta gttgaatgcc
     2461 cattgggagc ccttccttag tttcgtaagt aggtaaacta atagctggct ggccagttag
     2521 attaggcaga gctgtgtaag gattaatagc cagactctta ccaaacatgg tttcgaccaa
     2581 attgaattgc tcgtcactgc tgaaaatttc agcttgagcc aagttagcca tgagtttcga
     2641 atctgggaca agttctccgt gcttaggagc tggtgtgttg gttgtgaacg tcaacaacag
     2701 gtcataagtc tcatgaaaac tagccatggt tgcactgtac gtatcccatt tttgaaggac
     2761 ctgtgagtaa cgccaagctg ggatgtcttt acctgattgg taaatagccc aggtcatggt
     2821 ttccatatcg tctttggtca tcggacgtcc aaaagtgtct tcaatatcag caaacatagc
     2881 agccgtttcc acactattca taatataata atgacgaatc acttctgtca tatttacagg
     2941 aaactcttcc aattcaacta gctgatgccc ttgttctctt agccaagtta ctgcttgtct
     3001 taaagctttt gcagtatcta aagatactgg gctaccgtca cttaaccgtt gataaaaagc
     3061 aattgtcaag ggacgttgta gcgattgata aatactatct tttgttaagg tggctagggg
     3121 gaaggggctt tccatttgtt ccatctgtaa atagtagagt agatttctag tatctctaac
     3181 ggatttggtc aaggcaaaat gaactgaggc tccttgccag cttcgataag aaccaggtcc
     3241 gacaggcatg cgcccacggc taggtttgag tccaattaag ccattaaacg aggctggaat
     3301 tcgaatagaa ccaccaccat cactagcagt tgctagtgca ctaattcctg atgacactag
     3361 agcagcagct cccccagatg agccaccagc atttcgtgta ttatcctttg gtaaattcac
     3421 tggtccgtgc aaactgctat cgctaatatt tttaaagcca aattcaggcg tgttggagcg
     3481 ccctaaaata ataaagccta aagcttctaa tcttttcaca aataaatccg ttttagttgc
     3541 ttgatactct ttaaacaatc tggaacctga ggttgatgag tgacctttta attcttgtcc
     3601 caaatctttt aaaaaaagag gcacaccagc aaaaggcaga cctgaaaaat ccctttgttt
     3661 ggcttcttct agggctgctt caaagcgttc tgaggtaata gcatttaagg tagggttcaa
     3721 ctttttagcc ttataaatag cctgggttac taattctagt ggtgtggtct gaccagtctg
     3781 aacagcaata gccatagccg tcgcatcttg ataagtcata gctactcttc ctttctaaga
     3841 tatgaatcct aaaacattct tttttattaa aacacaaata aaagaaaacc accattaaaa
     3901 ggttagaaat tagaatgtga tgtgtaagga atgtagacaa aacaatcaaa acataacatt
     3961 ttgaattggg gttaaagaga ttttttcatt aaaaataaac ctggctgata gttccttatt
     4021 gttgccagtt tacctggtct tctttaaatt ttttaagtaa atgtaaacca tcattagtaa
     4081 tatagccttg caactttgca actgcaatta actcagtata attagaaagc gtaatcaact
     4141 tgataccagc ttctttaaaa ttctgactag cttttggtaa ctcataagtg aaaatcgcaa
     4201 caactcccag aacgtcagct ccctcacgac tggctgctgc ggctgcatct agtaccgaac
     4261 cacctgttga aatcaaatct tcaatgataa ccattttttg gcctttaagc acacgcccct
     4321 caatctggtt gcctgctcca tgatcttttg gcttactgcg aatataagca aaaggaagag
     4381 tcattttatc tgctataatg gcaccgtgag gaatacctgc tgtagctgta ccagcgatga
     4441 cctcaacttc tgggaaatga gccctgatag tttccacaaa cccattctca attaaatcac
     4501 gagtcttagg ataagaaagg gtgacacgat tatcagtgta aataggtgat ttaatgccag
     4561 atgcccacgt aaaagggtct tcaggcttta aataaacagc tttaatatca agtaattgag
     4621 ttgcaatttg gcttgctagt gtcatttctt attctccttt ttcttcttta acagacaagt
     4681 gttggtttcc taatcttatc tgttagcctg cccactcagc ttttatggct tggtaagcag
     4741 ccactgggtc ttttgcctgg gtaattggtc gccctaccac aatataatca cttccaatac
     4801 gtcttgcttg gtttggagtc atcactcgtt tttgatcgcc aatattactg cctttaggac
     4861 gaatgccagg agttaagcaa gtaaatcccg taggcgtcac cgccttgata gcttctactt
     4921 cttgtgccga acaaaccacc ccatctagct gagctttagc tgcccccttg ctgtaatgca
     4981 aaacagactc taaaagactc gtttgaatat tttgatcacc acgcatttgg tcttcactgg
     5041 ttgaagttag ctgcgttacc gcaattaagg tagggccttg acctagtcct tctcgagctg
     5101 cttttagcat ctctacacca ccagctgcat gaacagttgc catatcaata tctaattctt
     5161 taagaactgc catagcagca cgaacagtat ttggaatatc atgtaatttt aaatccaaaa
     5221 atacattatg ccctaacgat ttgatagacc gaacaatatc tggtccttgc gcataatata
     5281 attccatacc aattttcacg tatagttttt cttctgctgg aaataagtct aaaaatgctt
     5341 tagtctcctc aaatgatgaa aagtctaaag caataattgg gcgttcttct ttcataactt
     5401 atcctttcta taatgtgtca atatctcatt aagcaccaaa aagcctcgct accaaagaag
     5461 cgaggctaca gcaaactaaa agggaattcc ctttttttat cttgtatacc ttgtttgcct
     5521 ctctggactc acttaaaggt gtctaaattt aaactattat agctttttta aaacaagatg
     5581 tcaaaacttt ttgttatttg aacacatttt tcctactata tctttttttg tatacttacg
     5641 tcaactcatt ttatcatttt tacccaatca tttattcaaa ctcacctgtg ggtaccttag
     5701 ggctttggta atattttata aaagcttctt cttcaagatt aaccctctgg atatgttcat
     5761 agagcacatc cggaatagga gcttccttaa gtgacaaagc actcactttt aaagatgaaa
     5821 aaacatcact taagacccca aaaactcgaa tgcgtttatc tccaataata atttgaaaga
     5881 cttctttgga ctggcataaa tctatcagat gatccactcc tttaatccaa ttatcgacaa
     5941 tatccaaagt tttgttcatc aacttaaaag ctgattcttc ataccaaaag gtagactcaa
     6001 tcaagcgttg ctgcatatcc aaggtatcaa tggccgcaac aatatctccc aactcagact
     6061 gtactaaatg agctggaaat tcccctccaa gtatagaagg agttcgttct acaagcttca
     6121 gttcatctcg aaaaagagtc aaatagtgga tactgaccaa taacttttgg attaagattt
     6181 gatgactatt ttgttcagta acattcacac gaccaccacc ctttgattag aaaaatacct
     6241 atttgttaat actattaata taacacaaga aaaataaaag ggcaatgaaa ttgatagatt
     6301 caactctcaa aattgaatca tatttatcct aggtcatatt gagaaaagac tccagcgctt
     6361 tttcaaagtt ctaaacccat gatgacgttt gtgcttgcgt ctttattttt tttgagctag
     6421 actgtactta tgagaattca acaactgcat tatattatca aaattgttga gtgcggctct
     6481 atgaatgaag ctgctaagca attatttatc acacaaccaa gtctatccaa tgcggtcaag
     6541 gatttggaaa tggagatggg cattaccatt ttcaaccgaa atcctaaagg gatcaccttg
     6601 acaaaagatg gggtggaatt tttatcttat gctcgccaaa ttatagagca aacatcactg
     6661 ttagaagacc gctataaaaa ccacaatact ggccgagagc tctttagcgt ttcatctcaa
     6721 cattatgcct tcgtagtcaa tgcatttgtc tcactcctca agcggaccga catgactcgg
     6781 tatgaactct ttttgcgcga gacaagaact tgggaaatca ttgatgatgt caaaaacttt
     6841 cgatctgaaa ttggtgttct ctttatcaac gactataacc gagatgtctt gaccaaatta
     6901 tttgatgaca atcatttgac tgcctctcca ttatttaagg cacagcctca tatttttgtc
     6961 agcaaatcaa atcctctagc aactaaaagc ctattaagca tggacgactt gagagatttt
     7021 ccttacctga gctatgacca agggattcac aactcctttt atttttcaga agagatgatg
     7081 tcccagatgc cccacaataa atcaattgtg gtcagtgacc gtgccaccct ctttaactta
     7141 atgattggtt tagatggcta caccgttgcc agtggtattc taaatagcaa tctaaatggt
     7201 gaccagattg tggctatccc gctagatgtc cctgacgaaa ttgacattat ttttatcaag
     7261 catgaaaaag ccaacttgtc caaaatgggg gagcgtttta tcgaatacct tctcgaagaa
     7321 gtaacctttg attaatttct ttttcaatcg tcatactaaa aaaacacggt agtaagacct
     7381 gtatcggtca agttatcgtg ttttttgata aatatcagac aatagattgt ctccaaaggc
     7441 tcaactcctt tttaataatg gcattcatgt catcaaagta aaaaggctca cgtcggtaga
     7501 ttacaccaga aaaagtcgcc aaggtgataa tgttttccaa aaaagcctga gaagaaaaat
     7561 gagtggtgcg atgcagttcc tcttcatcaa aaggcttaat caaatgagcc agaggattac
     7621 ggacagcctt ttcaaaatgt cgtaacaaaa aacccaagtc cttgatttcc tgaggtaagg
     7681 aggtcaacgt caacatgtct gctaagcttt tggtcgtcac attgcgagac tgcttttgag
     7741 acaggtaagc cttgaaaacc tcgtgatcag attccaacat ggcctgaaaa tgccaggtat
     7801 catattggtc attctttgta tcaaaaatat aagccttgaa gtttggaatt tctgacgtga
     7861 ttagtctgag aaaaagtcgg taaagaatag gcgacactga cctgacgaaa tcaataatag
     7921 caccgttttt tactttaact tctaaatcca aaatgtaatt ggcaatctgc tcatcttcaa
     7981 gcgattggtt aagccataat gaacagtggt actggtcttc aatggtccga ttctctgctg
     8041 catgttccgc cagaaaggca aggttcaatt ctctgcgctc ttttaacatc tctagtaaat
     8101 agagggcagt tttagggata tttggcaagg ctttagcaat tctaaaggcg tgattataag
     8161 catagacatc caaaaggatg tctagtgttt gattattagt cattggcaat taaagtttcc
     8221 aaaccaactt tcatcatatc agtgaaagtg gtttgacgct cttcagctgt agtatcttcg
     8281 gttggatcat tcaagttatc tgagatcgtc atgattccaa gggctttgac atggtgctga
     8341 gcagctaaat agtaaagagc tgctgcttcc atttcgatgg ctttaacacc caatttacca
     8401 agagccatat tacgctcagg catgttagtg taaaagacat cagaagaaag cacattccca
     8461 acgtgagttg ttactcccat ttctctggcg atatggtaag ccttgtcaag taaaccaaaa
     8521 tcagcaattt gtgggaaatc aaattctggg aagtcattac ggataatgtt tgagttggtt
     8581 gctgctgctt gggcaagcac caattcacgc acatgaactt ctgggtcaat cgcacccgca
     8641 gtaccaacac ggatcaatgt tttgacaccg taatcaacga ttaattcacg agcatagata
     8701 gagatcgaag gcatccccat accagttccc atgacagaaa cgcggtgccc tttgtaagtt
     8761 cctgtgtagc caaacatgtt acgcacttcg ttaaaacaca ctgcatcttt taggaaattt
     8821 tcagcgataa atttcgcgcg caaagggtct ccaggtagaa gaattttatc agcaatatca
     8881 ccttttttgg cagaaatatg gatagacata aattatgata ctgagggcgt taaaagaacg
     8941 atggcaaaat aggaagttgg cagaaaatcc tgattttcta gacaacttat ctttttgacc
     9001 aagtccttag cccgaattca aattaatgaa ctcagccctc acctttctta tttttttatt
     9061 ttttataagg aagaaaaaca gttctccgcc cgtattcaat tcaatgaata cagttagccc
     9121 tacctttcct tttattttgt agaaggtcag agggcggaca gaaagcgact gaaatttagg
     9181 gaactaacgc catgtgtgag ctcaaaagtt agtttatcta gtttccgagc tttccgcccg
     9241 tattcaattg aatacaaccc cattcctttc ataattgata ttgaatagaa gagagctaaa
     9301 aatcgagttc aaataagaaa ggactaactc tctttccttt attatttaaa aattaatacg
     9361 aagaaatgtt cgagtccata ctcaatttaa accgaatacg tctctttccc ttcgttggtt
     9421 atgttagtta gaaaagctag aatctgagtt caacattcat ggaactcaca ctccgtgatt
     9481 attttttgat ttttttattg cgaacagatg tgccaaactg acgacataaa ataacattcc
     9541 tgtaataatg ctccagttga ttttgttcgt cctacaactc cgctaaaata gctttaacaa
     9601 gacctttgaa atcttctttg atatgttggg tcacttccac aacttcttca tggttcaatt
     9661 ctgattgaaa accagctgca aagtttgtaa tagctgaaat accaagtact ttaagtccag
     9721 aatgagcagc cacaataact tctggtacag ttgacatgcc aacagcatct gctcctaata
     9781 ctttgaaagc acggatttct gctggtgttt cataagttgg accagtcaag cccatataaa
     9841 caccatcttc tagtttgatg ttcatttttt cagccacttc atgtgcctta ttgcgataaa
     9901 ccttagtata ggcatcagac atatcaggga agcgcggacc aaactcgtcc aagttttcac
     9961 cgattagtgg gttatttccg gtcatattga tatggtctgt gattgccatc aaggtacctg
    10021 ggccgtagcc gataccacca gctgcatttg tgacaagaac accttcacat ccaagagctt
    10081 tcatgacacg aacagagaaa gtcaccactt caagcggatt tccttcgtaa aaatggaaac
    10141 gtccttgtaa ggcgagcact ttacggccag ctaaatctcc gtaaactaac tttccagcat
    10201 ggccaacaac cgttgacttg ccccagtttg gaatatctgc ataatcaata acaatagcat
    10261 tttctacttc ttcagcaagt tcaccaaggc ctgaacccag aattaatcca aattcgggag
    10321 tttcaattcc tttagtaact aaaaagtctt ttgtttcgtt aattttagtc atcaatgaca
    10381 tctttttctc cttttacctc aatagggttc acactctcgc catcctcttt aatataagga
    10441 ctaggcaggg gaacaggaag aatatccagt aaggtctcag aaggacggca aagttttact
    10501 cctttgcgag tcacaacaat aggacgattg atcaaaattg gatccgccaa catggcatta
    10561 ataatatctt tctcagctac tgcttgattt gctaatccat aagcctcaaa ttcaggaaca
    10621 ttggttcgca agagttctct tgcagagatt cccatcgatt gtaagagctc aattaaagtc
    10681 tcccgattag gtggcgtctg caaatactca ataatagtag gctcaatacc tgcatggcga
    10741 atcatggcaa gaacattacg tgaagtgcca cagtttggat tatgataaat cgtgatttct
    10801 tccattatca actaattttc ttattttaag tgaccaagga atgactcccc aatcatggct
    10861 gtatcaactc caaaattttc tgcaacagtt gctgaaatat ccgcaaaatg cccctgtgga
    10921 ataagaccat ttccagtaaa ggatgcagag taggcaagca atggaatgta ttcacgagtg
    10981 tggtcggtgc ctgcataggt tgggtcatta ccatggtcag cagtgatgag aagcaaatcg
    11041 tcttctttca tatttgcgat gatttcaggt aggcgattgt caaattcatg caagcagtcg
    11101 cgataaccct ctgggtcacg acgatgacca aagttggcat caaaatcaac gaggttagta
    11161 aaggagaatc ccttagtaaa ctcaggtaat tgaagagtct taataagcgt gtcaatacca
    11221 tggctgttcg acttattgtg tcccatgtcg tttgtaatac ctgaaccatt aaagatgtca
    11281 ttaatcttgc caacggcata agttgggacg cctgcgtcag ccagtttgtt caaaacggta
    11341 tcttggaaag gagacactgc atagtcatga cggttagccg tacgtgtaaa gtttcctggt
    11401 tcgcctacat aaggacgcgc aataatacgg cctaaaaggg cagggcgttc aagcgtgatg
    11461 gagcgagcat attcacaaat cttgtaaagc tcttccacag gaataatgtc ttcatgggct
    11521 gcaatttgaa gcactgggtc tgctgaggtg taaacaatca actcacctgt ttccatttga
    11581 cgcggaccaa aatcatcaat aaccgcagtt ccagaatagg gtttattagc ttcacgaata
    11641 attttgcgac ctgagaattc ttcaatctta gttaaaatct cttctgggaa accattccag
    11701 aaagtgtcaa aaggttccgt aatgttcaag cccataattt cccaatggcc tgtcatggta
    11761 tcttttccaa gagatacttc ttccaattta gtcacgtaac cagtaggatt gtcttctgtt
    11821 ggaacagttt ttagtggtat tggacgagaa atgtttccaa gtccaatttt tgccatattt
    11881 ggaaccgata agcctgctgt ttctgaaata tgaccgaggg tgtcagaatc tgtatcagct
    11941 acaccagcat taaagaattt gtcagcatct ggtgctgcac caataccgac agagtctaaa
    12001 acaaccaagt gaatacgatt aaattttgac ataagtctcc aatctagggg aggttacggt
    12061 tgactcccca atacctataa aatatattaa cgctgttata tgctaagact agcctgctgt
    12121 aggcgcttct aaaacagtaa cgccgtcttt actagcaaca atcaccttat caaccatacc
    12181 attaaagaga ccgtgttcca caacaccaac tgttccatct agcaggtaac caaaagcaac
    12241 aggatcttta atacaaccca aatcaagatc aataatatag ttttgcatgt ctgtcaccaa
    12301 acgactatca cctttcatac gaaaagacgg tttgtaacca gctttttcaa agacacggaa
    12361 caaacgatca gcaccatatt gaacgacttc gactggtaat ttaaaggcac ccagatgctc
    12421 taccatttta gaagcatcaa caacccagat gtattctttt gttggtgttg caacaatttt
    12481 ttccattagt aaggctgcgc caccaccctt gattccattg aaatccttat ccacttcatc
    12541 agcaccatct acggtgaggt caatgctatc aatatcatct atcgatttta aaggaatgcc
    12601 taagccttct gcttgcttgc tagtcacact tgacgtggtc acaccaacca cttgcagtcc
    12661 ttcttgcttt acgcgacggc caatttcctc aacaaaatag taagccgttg acccagttcc
    12721 aagcccaatg gtcatgccat cagtcacata ttgcgcagcg gtaacaccgg caattttttt
    12781 gagtgcttcc atgattcccc cttataatag aattgcgtct tagcacttta ttataccatg
    12841 aaagcgccaa cttgttaatg aaaacatttg tttttctctc attgatagtc taagtgctat
    12901 agaataggat gatcttttta aaacttatga tttattctaa agtcatcata taagcactta
    12961 cttttcgtgt ttatttagct ttttgaaaat caagtgtttt tgtttgacct ttactgacct
    13021 tttgattata ataatactat aagatgagta aaaataatgt ctgaatcatt ttattagcaa
    13081 agggtttcct atcatgtgaa atcctaacaa cgattctgcg actgcttaca aacatcttat
    13141 agtctatttt ttattgcgag gtaactgata tgacacattt ttctggtaaa gatccttttg
    13201 taaatatgga tgatattttc aaccaattaa tggcaaacat gggtggttat cgtagcgaaa
    13261 atccccgcta tctcgttaac ggtcgcgaaa taactcccga agaattccaa cactatcgtc
    13321 aaacaggaca actccctgta gcgacaacca aagcaacaaa ttctcaaatg ttaacaccta
    13381 aagctgatag tgtattgact caactcggaa ctaacttaac acaagaagct cgtcaagggc
    13441 atcttgaccc cgtcattggt cgtaacaaag aaattcaaga taccgctgaa atcttggcac
    13501 gacgaactaa aaataatcct gtccttgtcg gagatgctgg tgtcggtaaa actgcagtca
    13561 ttgaaggttt agctcaagcc attgttaatg gagatgtccc agctgctatt aaaaacaagg
    13621 aaatcgtatc aattgatatt tctagtcttg aagctggtac acagtatcgt ggttcctttg
    13681 aagagaccat tcaaaacttg attcaagaag taaaagaagc tgggaatatc atcttatttt
    13741 ttgatgaaat tcatcaaata gttggtgctg gtgccacaag cagtgattca ggctcaaagg
    13801 gacttgcaga tattcttaaa ccagccttgt cacgaggaga attaacactg attggtgcta
    13861 ctactcaaga cgaataccgc aatactattt taaaaaatgc tgctcttgct cgtcgcttta
    13921 atgaagttaa agtgaatgca ccatcagctg aagatacttt tcacatttta atgggtattc
    13981 gtaatcttta tgaacaacac caccatatta cccttcctga taatgttcta aaagctgctg
    14041 ttgattattc tattcaatac atcccacagc gtagcctgcc agataaagca attgacttac
    14101 tggatatgac agctgctcat ttagctgcgc aacacccggt cactgactta aaaacactcg
    14161 aaactgaaat agctaaacaa aaagagagtc aagaaaaagc tgtcgccaaa gaagactttg
    14221 aaaaagcttt agcagcaaaa acacggattg aaacattaca aaagcaaatt gagcaacata
    14281 accaaagcca aaatgtcact gctacagtca atgatatcgc agagtctgta gagcgcttaa
    14341 ctggtattcc tgtctctaac atggggacta atgatttaga aaggctcaaa ggaattagca
    14401 gccgcttaaa aagccatgtc atcggacaag atgaggctgt cgcagcagta gcacgtgcta
    14461 ttcgacgaaa tcgggcaggt tttgatgatg gtaaccgtcc aataggttct ttcctttttg
    14521 tgggtccaac tggtgttggt aaaacagagt tagctaaaca attagcactt gatttatttg
    14581 gctccaaaga tgctattatt cgacttgata tgtccgaata taacgatcgc actgctgtgt
    14641 caaaattgat tgggacaacg gctggttatg ttggctacga tgataataat aataccctaa
    14701 ctgagcgtgt tcgtcgtaac ccttatgcta ttgtcttact agatgaaatt gaaaaagctg
    14761 atcctcaaat tattacactt cttctacaag tgttagatga tggacgattg acagatggac
    14821 aaggaaatac tattaacttt aaaaataccg ttattattgc tacatcaaat gccggttttg
    14881 gccaacaaga tacggaaact tctgagtcta acattatgga tcgcattgca ccttatttca
    14941 gaccagagtt tttgaaccgt tttaatagta tcattaaatt taatcatctg caaaaagaaa
    15001 gtttagaaga aattgttgat ttaatgctag ctgaagtaaa tcaaaccacc gcaaaaaaag
    15061 gtattagttt aacgattgct gatgacgcta aagctcattt gatagattta gggtacaatc
    15121 acgctatggg agctcgtcca ttacgacgta ttatcgaaca ggaaattcgt gaccgtataa
    15181 ctgattatta tcttgaccat ccagatgtca aaaaacttca ggcaatccta aaagaaggac
    15241 aactagtgat taggcaaaaa gatcagtaat aaacttcttc aattgaataa ttttcaaaac
    15301 atgaaaaaat ccgtcttgtg actacgttat acacttgacg gacttttttt tagcgctttt
    15361 ttaaaaataa ttttttcatc gcctaataac tcaagtttct ttccaaatct ggtgtaatca
    15421 aaataaccat taggtgtgag caatcctttt gaaaaagaag tatgtcccgc tgctacttct
    15481 tctttgatat caatggtgtg caaaatacga ttaacttttc ctttgagaac aacagcagat
    15541 aaatgtcctg ttttttgatt atatttgcct ccgatctgag aagctaattt ctcaaaagct
    15601 tgatctaaaa tcatttctaa ttcatggcta gctggcatac tattctcaat aatttggcgt
    15661 tctttactac tcaagtcacc aacaactaaa tgattttcct ttaatgtctt taataattca
    15721 ttttggtgat aagcagctaa acgtttgaca aaaatgtctc gttcaacttg aacactaaaa
    15781 ctcaagtcaa cgttgttatt tttaactgtt agtatcatct gagatgacgt taataaacta
    15841 tcatcaataa gagggctctg atgcaaacca gtaagacgtt tagcaaaatc atcgcctaac
    15901 ttctgatcaa tgcttgttgt tcgccagata ccttcaatag agctattacg atatcgaaca
    15961 ccaaaaagta cagcaagcaa gataagaaaa ataataaata caaaaagggc attgcattga
    16021 tggcataaca atgactttcc tttagagcgc ccttgggcta cttgtgtcat gactcatctc
    16081 cttaatataa aatactagca tgtcatcatt aaggcgtcaa gtaaaatcgg taaacctaac
    16141 tatgattttt tatgttttcg ataagaaaaa caccctctac tgagaatgtt ttagcataga
    16201 taaatcaaca cctatcgcta gacctgctct aaaatagcat cccaagaatc atcgatacca
    16261 atacgttcta ccgaagaaaa tactataaaa gtatcagatt tgtcaaaatt caaagctttc
    16321 ttgaccacag actcatgttt gttccatttg ccacgaggaa tcttatctgc tttggttgcc
    16381 acaacaataa caggaatgtc atagtacttc aaaaagtcat acatctgaat atcttctttt
    16441 gaaggggcat gacgtaaatc aaccaaactc acgactgcac gcagattgtc tctgctggtt
    16501 aagtattctt cgatcatctt tccccatttg gcccgttcac ttttagaaac cttggcatag
    16561 ccataaccag ggacatccac aaatctaagc ttgttatcaa tattgaaaaa atttaatagt
    16621 tgggtttttc ctggcttgct tgaggttctt gccaaatttt tgcgccccaa tatggtatta
    16681 ataaaacttg atttaccaac atttgaacgt ccagcaaggg caatttctgg caaatcatct
    16741 tgggggtaat gagatttatt ggcagcgctc aataaaattg aggcgttatg ggtatttaag
    16801 acttgttctt cagccattat ttctccttaa gctgtctcta aaacgggttt tgacttgcct
    16861 tcgacagcag ccttggtgat acgcactttt gtgacatctt cttggcttgg aatttcaaac
    16921 ataatgtcta acatcgtttc ttcaataata gaacgaagac cacgtgctcc tgttttacgt
    16981 tcaatggctt tattggcaat ggcttctaag gcttccttat caaatgccaa ttcgacgcca
    17041 tcgtaagaaa gaagggcctg atattgcttg accagggcat ttcttggttc tgtcaaaatt
    17101 tgaatcaaat ctgatgtgtt tagttgttca agggctgcca caactggtaa gcggccaata
    17161 aattctggaa taagcccaaa cttttgaata tcttctgaaa taatttcttg catataagaa
    17221 gcattgtcat caattttacg gctgttttga ccaaaaccaa taactttttc acctaaacgt
    17281 tgtttaacaa tctcctcgat gccatcaaaa gccccaccaa caataaacaa gatatttttt
    17341 gtatcaattt ggatcatttc ttgattaggg tgcttccgcc caccttgtgg gggaacactt
    17401 gctaccgtac cttcaataat tttaagaagg gcttgctgta caccttcacc agatacatca
    17461 cgtgtgatag atacgttctc acctttttta gcaatcttat ctatttcatc aacataaata
    17521 ataccacgct ctgctcgttc gacattatag tcagcagcct gaatcagttt gagtaaaata
    17581 ttttccacat cttctccaac ataccctgct tcagtcaaag aagttgcatc tgcaatagca
    17641 aatggtacat tgaggctttt agccagagtt tgtgctaaga aggtttttcc tgaacctgtt
    17701 ggtccaatca tcaaaatgtt ggacttttgt aaatccacat catcgtcatc acgactttct
    17761 gtaaacgaga cacgcttata atgattgtac acagcaactg ataaagcacg tttagcacga
    17821 tcttgaccaa ccacatattg atttaaaaca tcaaggagct cttttggttt tggaacttct
    17881 gtcaaatcgg caaggacttc ttcagccaat tcttctttta taatttcttg tgataaagct
    17941 acgcattcat tgcagatgaa aacattattt cctgcgataa tttttttaac gtcatcctgg
    18001 cttttaccac aaaatgaaca gtatacttta atatcgttag ttctacttcc tgccatttct
    18061 tataattctc ttactttctc ttatctttta ctgaatttta atattagtca atgtgttgta
    18121 ttggtttttg gtgattcttg cttgatagct aaatcttcac cagtgctgtc tttgcaagtc
    18181 acatctcaaa acaatgtacc atagaaggcg tgaatactat taaccagatt agtaaacgca
    18241 tttaataaga acagacttcc taagccataa cgattctttt taaaagctgg gatggcacaa
    18301 agaacacaaa tcacgcacaa aaaagccgta aatactccaa aaatactacg ttgcatcgct
    18361 tatcatctcc tcagactatt tgtgttttaa agcagtaacg gtaaaatcat aaggattttt
    18421 agcgtctcga gcatagaacg tttggctttc ttgcgtaaaa tgactaaaat ctagattggg
    18481 tcggtaggta tctcctttaa aacgatgatg gataactgtt tttatgatac gatcgaaata
    18541 accattaaac gcttctaaaa ccttattccc accaatgata taaagtgttt tatcctgcgc
    18601 atggtaccac tccaagactt tttcaatact agtcattgtc aacacctcat ctacttgata
    18661 atctctattt cttgtcatga caagggtttg acgttgagga agtcttttgc aattcattcc
    18721 ttcaaaagtc acacggccca ttaagattgc ttgatgtagc gttgtctttt taaaatgttc
    18781 taactctttt ggtaaatacc atggtaactt acccgcaaca ccaataagcc ctgcttcatc
    18841 ctctgcccaa atagcaataa tttcctttgt cattaattat ttccttcatt ttaaactcta
    18901 tttattttac caaatttatg aacaaaatgc tcacaaaaaa tctaaataaa gtttaaatag
    18961 caaggtcaaa gtgcaactga ggcttcactg gatcataatt ttgtaattca aaatcatctg
    19021 gtttaatatc aaagaaatta gtcccatctg gaacatttaa aacaagctta ggctgactgg
    19081 caactggctg tcgttttagt aattcttgag cctgatcaaa ttggttgtca taaatatgta
    19141 aattgttaac aaaataaaag aacttaccta ttttccatcc aaaatgttta gcaatcatca
    19201 tctgcaaggc aacgtattgc atggcattga tgtgatgagc aactaatatg tcattagaac
    19261 gttgcgtcaa actagcatct aaataaagat cttcccctac acgtctaaca tcaaacatga
    19321 tttgaaaggc acatggcaac aacccttttg tctcctcaaa tgcttcatag tcccagagag
    19381 aaatgacatt acgacgattc caaggatttt ctgctaattg ctttagtatt tttgagatga
    19441 tatcatgttt tttgactaca gcaccataac gttgtccaat agtacgtgtc tggtcaactt
    19501 cccattcatt ccaataatga acattatatt tagcttctag cacatctaaa ctgttagact
    19561 gatcttgata tatccaaaat aattccttta tagcagattt aattggaatg ggtcgtaaag
    19621 ttgtgatggg aaactctcct ttagctaaat catattcagc aaacgcccca gtaatatact
    19681 tagaatgagc tgttcgacca tctttatatt taggacgtgc ttgctcactc aatgatcctt
    19741 cgtttataat tttttgaata ttagctttaa aaatctggtc agcttttgtc atctctaata
    19801 acctttctgt aagcatactt catactattc taactaattt taccgaaaaa taccagaata
    19861 aataaacatt cgaaaaactt catgtggtca tgaacatttt aactattaaa ggataaaaca
    19921 aataacttta tcagtctaat tttgcagtaa aatgtgatag aatgggtaag actataaaaa
    19981 taactaaaag aaggacaaat atgacaattg gaattgataa gattggtttt gcaaccagtc
    20041 aatatgtctt gaaattggaa gatttagcgc ttgcacgcca agtggatcca gcaaaattta
    20101 gtcaagggct actcattgag tcttttagtg tggcaccaat cactgaagac attattactt
    20161 tagctgcttc tgcagcagat caaatcttaa ccgacgaaga tcgagctaag attgatatgg
    20221 ttattttggc aactgaatcg agtactgatc agtcaaaggc atcagctatc tatgtacatc
    20281 acttagttgg tatccagcct tttgcacgtt cctttgaagt aaaacaagcc tgctatagcg
    20341 caactgctgc tctagactat gctaaactgc atgtggcttc taagccagat tctcgtgtcc
    20401 ttgttattgc tagtgatatt gctagatacg gtgtaggatc tcctggcgaa tcaactcaag
    20461 gctctggtag tattgctctt ttggtaactg ctaaccctcg tattcttgct ctaaataaag
    20521 ataatgtggc tcaaactagg gatattatgg acttttggag gcctaactat agtttcacac
    20581 cttatgttga tggtatttac tctaccaagc aatatctcaa ttgcttagaa accacgtggc
    20641 aagcttatca gaaaagagaa aaccttcagt tatctgattt tgctgcagtt tgtttccata
    20701 ttccatttcc caagttagcc ctaaaaggtc taaataacat tatggataac acagtacctc
    20761 ctgaacacag ggaaaaacta atagaagcct ttcaagcttc tattacttat agcaaacaaa
    20821 ttggaaatat ttatactggc tcactttatc taggattgtt atctttactt gaaaatagta
    20881 aagtattaca atctggagat aaaattggtt tttttagcta tggttccggt gccgtaagtg
    20941 aattttattc cggtcagtta gttgctgggt acgataaaat gttaatgact aatcgacaag
    21001 ctttactaga tcaacgaaca cgtctttccg tttctaaata cgaagacctt ttctacgaac
    21061 aagtccaatt agatgataat ggtaatgcca attttgacat ttacttaact ggaaaatttg
    21121 ctctaacagc catcaaggag catcgaagga tctatcatac caatgacaaa aactaatctt
    21181 aactggagcg gtttttcaaa gaaaacattc gaagaacgcc tccaacttat cgaaaaattt
    21241 aaactactta atgctgaaaa cttaaatcaa ctcaaaacag acgttctttt gcctatccaa
    21301 acagctaatc aaatgactga aaatgtctta ggacgattgg ctttgccctt tagcatagct
    21361 cctgattttc ttgtcaacgg ttcaacttat cagatgcctt ttgtcacgga agaaccttct
    21421 gttgttgctg cagcatcttt cgcagcaaaa ctaatcaaac gctcaggcgg ttttaaagct
    21481 caaaccctaa accgacaaat gattggtcaa attgttcttt acgatatcga ccaaatagat
    21541 aacgctaaag ccgccatcct tcataaaaca aaaaagctaa ttgcattggc aaataaagct
    21601 tatccttcca ttgttaaaag aggtggaggc gctagaacca ttcatttgga agaaaaagga
    21661 gagtttttga ttttctatct gactgttgat acccaagaag ctatgggagc aaatatggtc
    21721 aatactatga tggaagctct tgttcctgat ttaacaagac tgtctaaggg gcattgtcta
    21781 atggcgattt tatctaatta cgcaacagag tcgcttgtta ctactagttg tgagattccc
    21841 gtgcgccttt tagatcacga taaaacaaaa tccctacagt tagctcaaaa aatagagcta
    21901 gccagccgac tagctcaagt agatccttac cgggctacta ctcataataa aggtattttt
    21961 aatggcattg atgcagtggt aatagccaca ggaaatgact ggcgtgctat tgaagcaggg
    22021 gcccatgctt atgcctcaag aaatggtagc tatcaaggac ttagtcagtg gcattttgac
    22081 caagataaac aagttctgct tggccaaatg accctcccta tgcctattgc tagtaagggg
    22141 ggatctatcg ggcttaaccc tactgtttct atcgcacatg atcttcttaa tcaacctgat
    22201 gccaaaacat tagcccaatt gattgcatct gtggggttag ctcaaaactt tgctgcacta
    22261 aaagctctga cctcatctgg catacaagct ggtcacatga aactacatgc gaaatcatta
    22321 gctcttttgg cgggggcaac ccaagacgaa attgctcctt tagttaatgc tttactagct
    22381 gataaaccaa taaatctaga aaaagcacat ttttacttat cccagctaag acagtcttag
    22441 atttaaacaa ctaatataag gcaaacaccc atgtaaacaa ttggtttaca tgggtgttta
    22501 atctttgttt ctatacatac aagtcttaga aatagtctcc ataacatact ctatttactc
    22561 atctactcta ttctgagttt gatgaggtat ttataaatat tttatattat gttctaaaaa
    22621 agctctatca tctttgtagt aggtggcact attgtagagg tgatgaagcc taattgacct
    22681 gctgcaagcg tccatatagt aagtagtcga ctccctttaa ttctttaata gttttacagt
    22741 caagagcaca cataatgatt tttaattctt ctttccagcc gttaacgata gcaatcacac
    22801 gctcggttgg gtatttttcg accaattcta aaacggtgcg tgagagtccc actgcacgtg
    22861 ctcctaggac gaaacattta atcatgtcca aggggtgtct gacaccaccc gaagctaaga
    22921 tttccacttg gtccatcagt ccttgtgcat ttagcaagca ctgaacggtg gtttgtcccc
    22981 aatcgtttaa gtaagagcgg tctcctcctc tttgattttc aatataggca aatgaggtcc
    23041 ctcctcttcc tgaaatatca aaggtttgaa tgcctaggtc atgtgctagc ttgatactat
    23101 tgacatccat gccaaaacca acttctttga gaatgacagg aactggtatt tgactagcgt
    23161 attcagcgag gtgttttttc caggtatgaa agacgcgctc accctctggc atcagcaact
    23221 cttgcatcac attcacatga acctgtaaaa agaggggctg catttcttga accgtttgtt
    23281 gtcctagcgc cacaggttta tctagaccaa tattcgtggc tagtttcaag ttatctgcca
    23341 cctcatgtaa acgataggaa tcgtcgttag gattttttaa agcagcgcta taagaccctg
    23401 tcaccatgac aatccctgtt gctgctgcta ctttggccaa tttttcattg acagctttgc
    23461 ctttttgact tcctcctgtc atggcattga tgtaaaaggg aaagtcgaag tcttgcccgg
    23521 caaaatgagt actgagatca atatcagaca aatcatagct aggtaaggaa tgatgtatga
    23581 gttctatgtc atcaaaagca ttataaggcg attggtactt gagggcatat ttgatgtgat
    23641 catctttacg gttggtcatt ctctccccac ctttcttgat aaagtaatgc gatatcagct
    23701 tcttgccatt tggaaataag ggtatctctg gcattctgat taaaggcaag cgcgatgcca
    23761 caatctccac caccagaacc tgaagattta gcaacagcat cttgcttctg acaagcagct
    23821 accaaggtta ctagcttagg atggtagata gctgaatgaa gctcttttag gagatgactt
    23881 gctcctgcta aacttttctt gagttcttcc ttatgacctt cttgcaaagc taccatagct
    23941 gattgcgtta gctggtaact tgttcttaag aaagctgggg taatgctcgc tgtcacttgt
    24001 tgaatcatct gccttgaaat agcaggtatt ttagtccagc caaccaaaaa gtcacaaggc
    24061 agggctggtt gaatgacttg gatatggtaa ccccaatctt tgacgagaag tttttttaag
    24121 ggcatggtct gcagccagtt actgacctgt tctcggtcaa aggaggtata ggcgactaaa
    24181 gtctggtaag cgatacaggc aatatccccc atagacccat tatctccttg cttaagcaag
    24241 gtataagccg ctagtttaaa gagtaactct ggggttaaag tgatctgata ataggccgat
    24301 aaggccttta aggttaagag ggtgacgcta ccacttgaac caattccaaa ttttttgcca
    24361 tcgcgctcca tttttcccgt tatgattagg gaaaatggct ccagttggtc aattgactgt
    24421 cctagataat cagcaaaggt tttaaccgtt gcttgaatca gtgcataaga ggcatcgggt
    24481 gtcatgcccg ctttatgggc aaacatatct gaagctaatt gaatatgggc tgctgggcta
    24541 atttctgctg tcatcatcag tggaataaag tgaattaagg ctttttgtcc tggtgttaag
    24601 atagcatatt cgcctgtgag gtatagtttc ccacctgttt gcacacaata attagacatc
    24661 tggtaaatcc tttgtttttg aaacgataat acggtagttc ttgccaagtc gttctgctag
    24721 ttgagccaag tctttttcta aacataggac cttcacattt ggacctgcgt ccatggtaaa
    24781 ataacaagca aaaccttctt gacgcagttc tttcacagcc tccatagcct ggtaagactc
    24841 ttttgttagg taagaaaagg gaggattggc tgtctttgtc gtggcatgca tggccaaggc
    24901 attagcttct gttaactgac caactttctc aaaattatta gttttgagat aggtaagcat
    24961 atgttggtaa tcgattgccg attgttctac ccattgatca aatgtagttg aggtatcgcg
    25021 gcataacttc atgccctctc ggctagaaat tggctttttc gcagcattta agaccagcat
    25081 aatcatggcc attttcaagt cagtctcaac cttgtaaata gcaccactat ctttgtccca
    25141 agcagcgact gggccaaaaa aagaacgaga agatgatcct gaggcgaact tagccttttg
    25201 agctaaagct ttctgatcta gctgggtgtc aaataattga tcacaggctt taaccaaggc
    25261 tgataagcca ctggaacttg atgataaacc tgcagctgtt ggcatattat tttgagtttc
    25321 catctttaca aaagcctgac caggttggcg aaattggtca atgatagcag aaattttggt
    25381 atgttcttcg tcattttgta agacaccgtt aatgtaaaac tgatcactgg ttgcagtatc
    25441 tggtaagaag gaaacgctgg ttgtggtgaa catgttttcc aaagtcaaag aaatgctaga
    25501 ggtcgaagga atcatcttag cttgattctc ttttccccaa tatttgataa tagcaatgtt
    25561 agcataggat gttacggtta taacatttgg atccacgtgt ttacggctcc ttcttctttt
    25621 aatctgtgac tgattttttc ggccatgtct ttggtatctg ctagggcaat catacagcca
    25681 cccaagccac cgcctgtcat cttagcgcct aaagcacctg ctcttagggc agcctccaca
    25741 agttggtcag ctttactgat gctaacgcca atggccttta aagcagagtg cgcttgtgtc
    25801 atgagctgac cgatagccac cttatttttt tggttaatcg ctctttcaag ggcttgtgtc
    25861 aaagctccta gtttagccag atagggcaaa ttcgtttcct caaactgtgc taccttattg
    25921 acggcctcac gtgtatgacc gtgaatccct gtatctgcaa tgataagata accatttaag
    25981 gcgatttcga tagtttcaaa gccaatgttt cggataaact taatggcatg gtcactaagg
    26041 catgtcttgg catctaaacc actaggattg gtgtgggcaa taatttctgc cttgttgact
    26101 aaaatttcca acaaatcatc cgagaggggt tcttgacaat aagaaaaaac ggctctaata
    26161 gctgcaatag aaacggctgc cgaagacccc ataccacgct tttgtggcac ttgtgaaaca
    26221 atctcataag caattggttc ttgtagtcgc tgcaaataat ccaaggcagc ataaatggct
    26281 gttgatagag tatcataaaa atcaaagacc aatggcttat cagctggaaa aatatgacaa
    26341 accacctcaa tatctgttaa aggcaaagca atagctgggt agccatacac aacagcatgc
    26401 tcacctatca aaatgatctt actgtgtgcc ttaccatatc caatgttttc gttcattttt
    26461 tatcttttca ttactaattc ttctaaactt ttaccttact attttacact aaatgattag
    26521 aaaatgcgat gatatatctt tttaaaatca tttcttcact gaaattaaca ataaagacta
    26581 tctactcttt ttaggatcat aacaaaaatt ttcttatttc aaactacctt ctttaatcac
    26641 tcttctacta aattaaacgt taaaaaccag cctcatgggc tggttaagca tcgtttatta
    26701 cctttaccta gacattatta ctagctaaag gtactgaaaa atgtttaagt caaatcacca
    26761 ctgtaaaaac aatagcatcg tttttataat ttacagttat cgttccttta aataacttaa
    26821 ccatactttc tgccatagat aaaccaattc cataaccttt ttctttgcta ttatgggatt
    26881 cgtcttcgcg ataaaagcgt tcaaaaaagc ggctgtaatc aatggatttt ccttccaaat
    26941 aggtattaga aacttctaat ttcgctcgtt ttcgtcttct tccaatagtg gttaaagata
    27001 ccttgaccaa gcctttagga tcacaatatt tattggcatt atcaactaaa attgtcacaa
    27061 gttcaaataa tgacttttcc tccgctttaa tcataatatt cggctgaatc gtcaaatcaa
    27121 aacgtttacc atctttcaaa accagactct taaaatcttc agctgcatct tgagcaatag
    27181 ctgaaaagtc taccatatgt aataccacat ctggctgttc ctccaaacga gccaaagtaa
    27241 tcatttgatt aatcaagcct gtcaatcgct tcacctgatc acttgtactc ttggtccatt
    27301 ctgattctcc agtcattaat tcgaccaatt cattattggc tgagataatg gctagtggtg
    27361 tttttaactc gtggcctgca ttagtaataa agcgacgctg cttctcataa ttttggacaa
    27421 aaggtttgat gaccatacca gaaaaaagac tcactaaaac aacaaaaaag ataaatcctc
    27481 caaaggccaa catcattgaa acagctaata aatctcctac actacgaaaa taaaaggtag
    27541 tatctaaaat aacaaccagt ttttcttcat ttggcagctg agtaatcaag tacgaataaa
    27601 cactatcttg gtgacggtaa ctgccttttt cttccccaga cttagcaaaa agtctagcaa
    27661 aatattgggc ttcttctcta tctaaagctg aaatattagc agtattagaa gaaagtagat
    27721 gtccattagc attaaaaatg acactataat accgaaactg gcttaggcta tcttcagaca
    27781 gtttcgttcc aagtcgttta gagctttccg tagtgccagg taatttacct ttatttgagg
    27841 aaattaaatg taaaatacgg ttaatttctt gttgactttg gtaacagcgt gccgtgttaa
    27901 taataccaac aattgaactt aaaataataa aaatggcaat agaagcaatc atgataaaac
    27961 gaatacggat acgattaaac atgtcacctc ctatttttct aataaacaat agctagtatc
    28021 tttatcacct gcaataatga catttgcttg aatagctaat aatttttgac gaagataaga
    28081 aatataaacc caaacaatag aagtatcata atcttcttgg tctgaccaaa catgttggta
    28141 aagcgtttta gtatccaagt actttccttg atttaacatt aaaaaggcca ttaatttacc
    28201 ttctttagaa gctaatcgta tagcattacc ggcactcaat tcttgctcat taatatttaa
    28261 tgtgacacca gcaaattgta atacctgagg agtaaaactt tctactcgtc tttccatcga
    28321 ccttaatcta gctaaaagtt cttttaatga gaaaggttta gtcagataat catcagctcc
    28381 cgcatctagt ccggtaacac ggtcattaat ttctgccata gccgtcagca taataatatg
    28441 tgagcaattt cctgaagcgc gaatctcctt taaagcctca atgccagact taatcggcat
    28501 catgatatct aaaatcataa tatcatatgc attgtctttg gctttatcaa ttgcctcttg
    28561 accgttaaaa accacatcaa cgtcataacc ttgatgagtc atggcagttg tcaaaacatt
    28621 agacatctgc cattcgtctt cagctaacaa aattttcatg gttactcttc ctccgtcgtt
    28681 tcttgaatca attgacgaat ggtttgcatg gtaacatcac aagatgccaa ctcgtctgca
    28741 caacgcttta actctcttgt aatcatttct gcattagcaa cttgatgttt gtacttcatt
    28801 tgatgttcca agctagccca agagtcttga gcaatggttc gcaactgcac ttctataaaa
    28861 taacatcctt ttttttcccc taaaatatct ggaaaatgtg tttctaattc caaaatgaga
    28921 tgatatgatc tatagccatt aggcttggca tttaaaatat aatctttttc agtgttaact
    28981 gacataccag gaatgctttt gagcaagtct accatccgat aaatatcatc aataaaacca
    29041 caaataatgc gaataccgat actatcttta atgattttta atgcagattt gcttgttaga
    29101 ggaagttgtt tgcgttgaca tttttcaatc atcgaagctt ccgatttaat acgggatgta
    29161 aagtgttcgt atagtttaaa ccctgtttct tttttgcttt tgatattctc agcaataatc
    29221 acatctgtta ttgtctgtag taccaacggc aagtacactt caaatccgct atatatagag
    29281 ctggtagaat aatgttctag tctttctttc atacgcttat tataacaaat tttctcaaca
    29341 aatgcttaaa tctctacaat gatcggttat ctttatttct aactatataa ctgtaaatga
    29401 tctttatcgt ttgtttttaa atcgctttca tatatttttt gtacgttatt ttttaaaaat
    29461 accattgaat tacaaacaaa aacatagtaa acttgatcta taacgattac gttaacttat
    29521 taggagattt tatgaaaaaa tattttattt taaaaagtag tgtattgagt atcctgacta
    29581 gttttactct attagttaca gacgttcaag cagatcaagt tgatgtgcaa ttccttggcg
    29641 tcaatgattt tcacggcgct cttgataata ccggaacagc ttacacacca agtggtaaaa
    29701 taccaaatgc tgggacggct gctcaattag gtgcttatat ggatgacgct gagatagatt
    29761 tcaagcaagc aaatcaagac ggaacaagta tacgtgttca agctggagat atggtcggag
    29821 ccagtcctgc taactctgca cttttacaag atgagcctac tgtgaaagtc tttaacaaaa
    29881 tgaaatttga atatggcact cttggtaatc atgaatttga cgaaggacta gatgaattta
    29941 accgtatcat gacaggtcaa gcgcctgatc ctgaatcaac aattaatgat atcaccaaac
    30001 aatatgagca cgaagcttcg catcaaacca tcgtcattgc taatgtcatt gataaaaaaa
    30061 ccaatgatat cccctatggt tggaaacctt atgctataaa agacatagcc attaatgaca
    30121 aaatcgttaa gattggcttc attggtgttg tgactacaga gattccaaat ctcgttttaa
    30181 agcaaaacta tgaacactat caatttttag atgtagctga aaccattgcc aaatatgcta
    30241 aagaactgca agaacaacat gttcatgcta ttgtggtttt agctcatatt cctgcaacaa
    30301 gtaaagatgg tgttgttgat catgaaatgg ctacggttat ggaaaaagtg aaccaaatct
    30361 atcccgaaca tagtattgat attatttttg caggacataa tcatcaatac actaatggaa
    30421 ctatcggtaa aacacgtatc gttcaagccc tctctcaagg aaaagcttat gcagatgtcc
    30481 gtggtacgct agatactgat accaatgatt ttattaaaac tccatcagca aatgttgttg
    30541 ctgtagcacc aggtatcaaa acagaaaatt cagatatcaa agctataata aatcatgcta
    30601 atgatattgt taaaacagtt actgaacgaa aaatcggaac tgcaactaat tcttcaacta
    30661 tttctaaaac agaaaatatt gataaagaat cccctgtcgg taacttagta acaacggctc
    30721 agcttactat tgctaagaaa acttttccaa ctgttgactt tgctatgacc aataatggtg
    30781 gtattcgaag tgacctagtt gtcaaaaatg accggaccat cacctgggga gctgcacagg
    30841 ctgtacaacc atttggtaat atccttcaag tcattcaaat gactggtcaa cacatttacg
    30901 atgtcctaaa tcagcaatac gatgaaaacc agacctattt tcttcaaatg tcaggtttaa
    30961 catacactta tacagataat gatcctaaga actctgatac ccccttcaag atagttaagg
    31021 tttataaaga caatggtgaa gaaattaact taacaactac ttacaccgtt gttgtcaacg
    31081 actttcttta tggtggcggt gatggctttt cagcatttaa aaaagctaaa ttagtcggag
    31141 ctattaacac agatactgaa gctttcatca catatatcac aaatttacaa gcatcaggta
    31201 aaactgttaa tgctactatc aaaggggtta aaaattatgt aacttcaaac cttgaaagct
    31261 caacaaaaat taatagtgct ggtaaacaca gtatcattag taaggttttt agaaatcgtg
    31321 atggcaatat agtgtctagt gaagtcattt cagacctttt gacttctact gaaaacacta
    31381 ataacagcct tggcaaaaaa gaaacaacga taaacaaaaa tactatctct agttccactc
    31441 ttccaataac aggggaaaat tataaaatgt ctcctattat gacaatcctt gccttgataa
    31501 gcttaggtgg actaaacgct tttattaaaa aaaggaaatc ctagcgttta ctagtaatcg
    31561 atcaccctta tataatcagg catctttgcc aaaaaaacct aaagcgtcct actctaggtt
    31621 ttttgttaaa ttaaaatacc ttctagatga tctaattcgt gctggcatat ttgagcagtt
    31681 aagcctgtta agcttaatcg ctttggtcgc caattatggt ccaaatactc aacagtaatc
    31741 ttatcatacc gctgtgtttt gcgatagcca tataacgaca aacaagattc tttagtttgg
    31801 taaattccct ttttagaaac catcacagga ttaaacatca ccaaatcaat aaatcccata
    31861 ctcacaataa caatgcgctt ttgttcacca atcatattgg cagccatccc aagacattcc
    31921 tgtctataaa aggctaaggt atcttgtaaa tcttggccaa tccatagatc ttctttcttg
    31981 gcgacttgcg ctttttgctg taataaaaaa tgatctgtta tgatttctct aatcattctt
    32041 atctccttaa accttctttt taattcataa actacatgtt caatggacta ttatcaccat
    32101 aggatagact tagtatcatc tgtttaaaac atcaggtgat tccttatttc aagatatctt
    32161 gggcaacttt atgaaattct gcaatatgag tactaaataa aaattgacct gcatcagcag
    32221 attgttggta aattctcatc acaatattat cgaatttact gtctgcttct tcaaatgtct
    32281 aagagagatc gttattgctt tgtgagattt tcaaaccaga tactgctttc tcttgcattt
    32341 gcagccttga taggtccaaa caaaacacct gctgtttgaa atgctttaat agctgatatg
    32401 ttgttaatag ttagtattat aaattttctg aatatttctg tcaagttttt cagttgactt
    32461 aactttttta cttgattttt cctcacgtaa taatagaaaa gaagcgccat aatgtaaact
    32521 acaccccaaa cgttagataa aaaaatctaa cgtttggggt atttttgtat gacattaagc
    32581 tatgaagata agctagacat ttagcgctta aaaactgagg gaactccgtt tgaaagaagc
    32641 atctctgcaa agaagaagac aaaaaaccat tataaagaat ggacaaagac gagttctgat
    32701 tagattttct tttaagaacg gctaaagtga ctcgttctac ctactattat catcgattat
    32761 tgcaacaata aacgtatcaa aataaaacga aaaggactta gtcctctaca atacagaact
    32821 aaatccttta cttcaaatag agtagccaac ttttggggct cagtgcaaga gcacttcttt
    32881 tctattatca cttgtttatt ataaacataa cattaccata gtatacttat atgtctagtc
    32941 cactcaaata ctcaaaccgt tcatacgcca ataataaatc attattgcgc tgatcgagtt
    33001 ccttttgtaa ttgagctaac tggccataat cactaactac agttaacatt tggttttcaa
    33061 tttcttcaat attagcctca atagttgcta ttttatcttc tatctgagcc cattcttgtt
    33121 tttcaaggta ggacatgcgc tttttctcct ctttcggagg aagtggcact tcttcagtga
    33181 ctattgcttt agctaagtca gcctcaactg tttctttttc aaaagctttt tcatcaaggt
    33241 aatcactgta attcccataa aaaatacgaa tatcgccttc ttcaaaggct aaaatcttag
    33301 tggctacttt gtctaggaaa taacgatcgt gactaaccgt aatgactggt cctgcaaagt
    33361 tagctaaaaa gttttctaag accgtcaagg tggcaatgtc taaatcattt gttggctcat
    33421 caaggagaag aacatttggc ttttcaatga gcagttttag caagtagagc cgttttttct
    33481 ccccaccaga taatttagca atcagcgtgc catgacttga tctcggaaaa agaaattgct
    33541 ctaaaagctc actgatactc gttgttccca cgcttgtttt aacctcatca gccacttctt
    33601 gaaggtaatt aatgacccgt ttggtctcat ccatatcttt gagctgctga gagaaataac
    33661 ctacacgaat agtatctcca atatcaagct tcccagaagt tggtttgaga tcaccgttga
    33721 tgatatttaa cagggtagat tttccgacgc cgttatctcc aacaattcca atacgatctt
    33781 tattttgaat aatcaagtta aaatccttaa tcaactgtcg gtcgccataa gcaaaagaaa
    33841 ggtcttcaaa gtgaatcacc ttcttcccaa ttcggctcgt ttcgaaagcc atctccaatt
    33901 tatctgcaga actgtcttgg tgaacttctt ttttcaagtc agtgaaacga ttgattctag
    33961 cctgctgttt ggttgcacgc gcctgtggct gcgtcctcat ccaagctaat tcttgtttat
    34021 agagttgctt cttcttgtgt aaattagtag catctcgttc gtcttgttct gcttttaagc
    34081 gcacatagtc ttggtaattg ccttgatatt ctgtcagtcc cgctttatcc aattcaaaaa
    34141 tacgggtagc cacatgatca aggaaataac ggtcatgggt aataaaaagg acggtttttt
    34201 tagctgtctt gagataggtt gttaaccaag cgatggtgtc aatatcgaga tggttggtcg
    34261 gctcatccaa caagagtaag tcagcagctc ctagcaatac ttgagctaac tggacacgtc
    34321 ttctcatacc acctgatagg tctcccactt tttgttccaa atccgtgatg cctaattttg
    34381 ataggactgt tttgacatca ctttcaatag accaagcatc taagcgatcc atttcagaca
    34441 tgagggactc taagctttct tgtttatcct cagtataatt cgccatcaat agttcgtact
    34501 gacgaatcag ttgaatagct ttaacatcag ctgataatac cgtatctaaa acagaagctg
    34561 catcgttaaa ttcagggtct tgtgttaagt aagcgatttt gtaatcattg gctttagaaa
    34621 atggtgaatg gtctccgtca aaaccaagcc ttcccgacaa gacatctaaa agagttgttt
    34681 ttcctgttcc attaacccca ataatcccaa tacggtcaaa gtcatgaata ataaaggaaa
    34741 tatcttgaaa gacggtctta tctcccaccg tttttgttaa tttctccacc aaaaaatggc
    34801 tcatgttgct aattcctctc taacaaatgc ttcaattgta gtgaaatcat tatctaggcg
    34861 cccctctaca atcgctaatt caactttctc aagcataagc cctagctgag gacctggttt
    34921 catcccaaaa tccttaatca ggtgagaacc attaaggacg atatcgtgtt tgtcatgaat
    34981 aaccagtgcc tgatctaaag tattaatatg atccatgtca acggataagc tttgagcttt
    35041 tcggaggtct tccactagac tcgccatttt cttgccgtac tggtaaatat ccaatttttc
    35101 aaaagatctt tcctgacgaa ttctataaag agcaatcaac tttgtgacat aacgctgaaa
    35161 atcatttgaa gtcttccatg cttttaggaa gcttttagga tcctcaatgg ctaaactaat
    35221 catcacataa gcccaagctt ggtgatgatc actaaaggta aagttatctt tcaaagaaac
    35281 tatcagatga ttcaagcctg cttcctgctg cttcaagcct ggtaaatagt cataagcctg
    35341 acaagcaatc atggcagaaa tcccttttcg ccagtgcggt gccatcaata atttatcaaa
    35401 ttcagtaaaa gaacgttcca cagaaatctt ttccaataga ggtgaatggc tcctcatagc
    35461 ttcaaaagtt gtagcttcaa tgtcaaaatc cagactcgcc gcaaatcgaa agcctctcat
    35521 aatgcgtagt gcatcttctt caaaacgttc ctctgcttta cccactgctc gtaaccgttt
    35581 ttgctttaaa tcaatgagtc ctctaaattt atcaataact tgaccatttt catccaaggc
    35641 caaggcattg acggtaaagt ctcttcgttt taagtcttcc tctaaagagc gcacaaaaga
    35701 aacctgacta ggacggcgat aatcaacata gacatcttct gtcctaaagg ttgtgatttc
    35761 atactcaccg ccattttcaa gcacgagcac tgtaccatgt tcaatgccaa catcgacagt
    35821 tctgttaaaa atcgctttag tctcttcagg ataggaacta gttgcaatat ctacatcatg
    35881 aatgggacgc ccgagtaaaa tatctctgac gcttcctccc acaaagtagg cttcataacc
    35941 agcttctttt attttagtca atatgggtaa agccttctga aactcagaag gcattgtcat
    36001 taatttcata cgttgttttc taacctatca tccaactagc ccaatctaaa gtgtgattag
    36061 gctacttggg ttctatcaca ttttgttatt gttttagtga ttcttgcaat taactatttt
    36121 ttctaatcga caattaaagc ctcggtgtta cgccaaatgc aatggctcct tctcctaaat
    36181 gagtagcaat caccgctcca aaatgaacct cttcaatgtc atattgataa ccactgtctt
    36241 gtaagagtcg tttcaaataa tcagctttgt cttgtgcttt tgagtggata atagacacat
    36301 tatactgacc gtctgctatc aagtcattta aaatctcaac caagcgtttc atggctttct
    36361 tttctgttct cactttttca taaacaacga tttttccctc ttcatcaaag cgtaaaatag
    36421 gtttaatact caaaagattt ccaagaagag cagacccatt tgacaggcgt ccgcctttaa
    36481 ccagatgatt aaggtcatca accataataa aggctgtcgt cccatcaatc tgttcttgca
    36541 gcttgtttaa aatagcttga aatgtcattc cttgacgtga ccaatctagc acatttttta
    36601 ccatactacc taaaggagca gatgtgatct tactgtctgg aaatgccatt tcaatctcag
    36661 gatgttcttc agctaaaaat tgaatatttt gccaaaagcc tgagattcct ccagctaaga
    36721 acaagccaat aacatgtgta taacccttag aagacaaaag tcctaaaaga ttatctagtt
    36781 cagataaact tggctgactt gtcttgggaa gattttggga gtcagccatc ttttgataaa
    36841 aatcatctat actcaaattt cgaccttcaa aataggtctc atcgtcaatg ataactggta
    36901 tatcaaggct aaaaatagct ttatcttgtt tcagatctgt tggtagtgtt gctgtactgt
    36961 cagtaattac tgctaatttc attaattttt aaactccaaa tgaatacctg gacgatccaa
    37021 ggcaatttct gtgacttcat aagtcaatcg cttaaccatg tctagcaaag gagcagctaa
    37081 ggattcaact tcctcttgcg taaattcgct tggtttatcc actaaacgat ctaaaatacg
    37141 aaccatttgt gagatgaccc cactaataac aaattcttct ttgacaataa caaattgcaa
    37201 tacagataca attactgttt ctttttgctg ctcatcttta tcaatcaact gaaaagtcac
    37261 ttcaaaattg gtctctggtg ttccgttttc tttttcccac tctaaatttc tagcatcata
    37321 atggtactgg ttgacaaatt ctttttcacg aactaattgc attttttatt ctccttggta
    37381 tcaatatgat ccattatagc atagatttga aaattattaa agtagcccct aaactactat
    37441 tttcgcataa cgttttaaac agtgctatct ctcgaacaga tatctatttt ttcacctatt
    37501 tatatttagt cgtccttata ctgacattat accaaaaaaa cacccgttag tggtcttgta
    37561 ctgcacctca attaaaacag aaccattggt caggtaagtt ttaagtccag gataaaaagg
    37621 tttatcacca aggcctcatc atgcttagcc aagtatttcg aactagcttg tcttagctct
    37681 agtcgctcaa acgtaaaccc taggcgttca atccgccgca aaacctctcc aactaaccca
    37741 tacttaaacc catagggctt aatcatcgct cctcccttct tctcctttta tccattataa
    37801 aataaaaacg ttttaacaga caaaaaatag gaaagtaaca gactattgga tttatttttt
    37861 tatctcaaac tccattaacg atgttgagtt aaaggcattc aaaacaacat agctcgtaaa
    37921 ctaacaagat tttttatcaa ttgaacctat cgtccccagt tataccacga cctcttctgg
    37981 atgaggtctt tttttatttg tctaatttca tcaacgcttc ttcccttctt tcttctatca
    38041 cagctctcct attgctcact tcctcatgca gcaacatatc atcaaaaagc cgtccatttt
    38101 taagcacaac cactactgta tctcttgtga tatctccatt gccaatcgct tgtttacgtt
    38161 tattaaaaat tatttaaaaa attaaatatt attttaaaaa attgcaacaa aagatgtcta
    38221 tatgttataa tctttttata ataaaattat atagaaaaag gtattcttat gagaaaaaga
    38281 tgctattcaa cttcagctgc agtattggca gcagtgactt tatttgctct atcggtagat
    38341 cgtggtgtta tagcagatag tttttctgct aatcaagaga ttagatattc ggaagtaaca
    38401 ccttatcatg ttacttccgt ttggaccaaa ggagttactc ctccagcaaa attcactcaa
    38461 ggcgaagatg tttttcacgc tccttatgtt gctaaccaag gatggtatga tattaccaaa
    38521 acattcaatg gaaaagacga ccttctttgc ggggctgcca cagcagggaa tatgcttcac
    38581 tggtggttcg atcaaaacaa cgaaaaaatt gaagcatatc taaaaaaaca cccagataaa
    38641 caaaaaatca tgtttggtga tcaagaatta ttggatgtaa gaaaagttat taatactaaa
    38701 ggtgaccaaa caaatagcga gctttttaat tatttccgag ataaagcttt ccccggtttg
    38761 tcagcacgcc gaattggagt tatgcctgat cttgttttag atatgtttat caatggttat
    38821 tacttaaatg tttataagac acagactact gatgtcaata gaacctatca agagaaagat
    38881 cgccgaggtg gtatttttga cgccgtattt acaagaggtg atcaaagtaa gctattgaca
    38941 agtcgtcatg attttaaaga aaaaaatctc aaagaaatca gtgatctcat taagaaagag
    39001 ttaaccgaag gcaaggctct aggcctatca cacacctacg ctaacgtacg catcaaccat
    39061 gttataaacc tgtggggagc tgactttgat tctaacggga accttaaagc tatttatgta
    39121 acagactctg atagtaatgc atctattggt atgaagaaat actttgttgg tgttaattcc
    39181 gctggaaaag tagctatttc tgctaaagaa ataaaagaag ataatattgg tgctcaagta
    39241 ctagggttat ttacactttc aacagggcaa gatagttgga atcagaccaa ttaaagcgta
    39301 tcaataagaa agattacatt caacagatga tggtattcta aggactaata ctattgcagg
    39361 gaattttttt atagatgggc aacagcaaaa aacattaata aatcctataa aaatcgataa
    39421 ggatattgtt acgattcaag agttcgattt taaaataaga aaatttttga tggaatcaaa
    39481 agaaattcat ttgactaagt ctccttatat aagggggagt ttagaaattc acagtaaaaa
    39541 taggaaacat gaaaaaatca atttatatga cgcaaaaccc aatagcacca gatctgatgt
    39601 ctttaaaaaa tataaagaca ataagactat aaacatgaaa gatttcagcc attttgatat
    39661 ttatctttgg actaaataag ctaaaagctt tggataaata tgatcaattg acctataata
    39721 acattgatac caaatctaaa actgctcaga ttgaattgcg ccccaaaagt tagacaaaaa
    39781 atctaataat tggggtgttt ttgtctggca ttaagtttag ctaataacct tgcttaaatc
    39841 acattaaacc aataatggaa aaagacatct ccaaataaat gctatgatgg aactatatga
    39901 tagagtgatc aaggttggca atatcaacac aactattatc atcatttcct aaactctaaa
    39961 ggaattcgtc cgtctatgtc acgtaaaaga aacagtccta acaatagcat gatggaatct
    40021 ttctttggca tcttaaagtc agaaatgttc tatggttatg agaataacta taaatcacta
    40081 gaagacttag aacaagcgat tacaaatgac attgattatt acaacgataa acatatcaaa
    40141 gtaaaactaa aaggatttag ttctgtacaa tacagaacta aatcctttac ttaaaataga
    40201 gtatccagct tttttggggt cagtgcaagc agattgttgt tagtgttaca ttaataagtc
    40261 atgcgtttag cccaagcctc atcaactgct agggtctccg catcagtgta attacgacga
    40321 tactcattcc aaacataacc cgaagttgct agaccagttt cttgagctga gctattagca
    40381 acatcataag ccgtcaaacc ataggttgca ataatattat ttagttttaa gttataactg
    40441 gtgtctgtag cgtataagcc agttagagct gctgtagcat cttgatacga tagcgtgttt
    40501 gattttctag cacctatata agtgctagaa cttagcaagt ctgcatagtc attaagggag
    40561 tctgcaatac ttggataagc tctaaaggct tgatcaatcg tataggtatt gccattacca
    40621 tcatcttccc aagttgacat cgtcacagaa gaaccgttat aggcaccctt aataccgaaa
    40681 aaattataat aaggtgcttg acttagactt gatttaccat tacttgattc taaaatcgct
    40741 tgtgctatca taacagacgc ataaagatca cgttcttgac caatagtact agcagttgga
    40801 ccaatttcat caataaaatg tcgggttgaa gaactggcga tagtctcagc tgacacgttt
    40861 gaagttttat gagattgtct cattgcacta taagctccta aacaagctgc tagaacaaaa
    40921 agactgataa gtacaagctt acctttcttt tttgtcatta ttcacatatc cttttttata
    40981 cattttctat gtttctatta tagcacacga acgtttaaat taacttttcc acagataatt
    41041 taatgagatt gataactttt gtcttgaaat cgacatattt cttctgattt tttttaaaat
    41101 tgtggataac tatttcatta gaccatcaaa attagtgagt tgataccatt caatcaattc
    41161 atttaatttg gtatgg
//
